Motif ID: MESP1

Z-value: 1.109


Transcription factors associated with MESP1:

Gene SymbolEntrez IDGene Name
MESP1 ENSG00000166823.5 MESP1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MESP1hg19_v2_chr15_-_90294523_90294541-0.183.9e-01Click!


Activity profile for motif MESP1.

activity profile for motif MESP1


Sorted Z-values histogram for motif MESP1

Sorted Z-values for motif MESP1



Network of associatons between targets according to the STRING database.



First level regulatory network of MESP1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_167098059 4.995 ENST00000392764.1
ENST00000474464.1
ENST00000392766.2
ENST00000485651.1
ZBBX



zinc finger, B-box domain containing



chr4_-_16085340 4.983 ENST00000508167.1
PROM1
prominin 1
chr4_-_16085314 4.964 ENST00000510224.1
PROM1
prominin 1
chr11_+_73358594 4.254 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1


pleckstrin homology domain containing, family B (evectins) member 1


chr3_+_63638339 3.906 ENST00000343837.3
ENST00000469440.1
SNTN

sentan, cilia apical structure protein

chr20_+_56725952 2.978 ENST00000371168.3
C20orf85
chromosome 20 open reading frame 85
chr1_-_46089718 2.957 ENST00000421127.2
ENST00000343901.2
ENST00000528266.1
CCDC17


coiled-coil domain containing 17


chr16_-_776431 2.886 ENST00000293889.6
CCDC78
coiled-coil domain containing 78
chr3_-_50383096 2.790 ENST00000442887.1
ENST00000360165.3
ZMYND10

zinc finger, MYND-type containing 10

chr10_+_22634384 2.777 ENST00000376624.3
ENST00000376603.2
ENST00000376601.1
ENST00000538630.1
ENST00000456231.2
ENST00000313311.6
ENST00000435326.1
SPAG6






sperm associated antigen 6






chr17_+_4981535 2.745 ENST00000318833.3
ZFP3
ZFP3 zinc finger protein
chr19_-_7990991 2.547 ENST00000318978.4
CTXN1
cortexin 1
chr1_-_46089639 2.453 ENST00000445048.2
CCDC17
coiled-coil domain containing 17
chr1_-_75139397 2.335 ENST00000326665.5
C1orf173
chromosome 1 open reading frame 173
chr5_+_156693159 2.260 ENST00000347377.6
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr22_-_50970506 2.251 ENST00000428989.2
ENST00000403326.1
ODF3B

outer dense fiber of sperm tails 3B

chr4_-_177116772 2.225 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr16_-_21289627 2.212 ENST00000396023.2
ENST00000415987.2
CRYM

crystallin, mu

chr2_-_230579185 2.160 ENST00000341772.4
DNER
delta/notch-like EGF repeat containing
chr14_+_96949319 2.141 ENST00000554706.1
AK7
adenylate kinase 7
chr7_-_73184588 2.054 ENST00000395145.2
CLDN3
claudin 3
chr6_+_17281573 2.006 ENST00000379052.5
RBM24
RNA binding motif protein 24
chr15_+_82555125 1.996 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B



family with sequence similarity 154, member B



chr5_+_156693091 1.958 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
CYFIP2



cytoplasmic FMR1 interacting protein 2



chr11_+_827553 1.945 ENST00000528542.2
ENST00000450448.1
EFCAB4A

EF-hand calcium binding domain 4A

chr9_-_80263220 1.910 ENST00000341700.6
GNA14
guanine nucleotide binding protein (G protein), alpha 14
chr20_-_39317868 1.882 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr1_+_151682909 1.842 ENST00000326413.3
ENST00000442233.2
RIIAD1
AL589765.1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
Uncharacterized protein; cDNA FLJ36032 fis, clone TESTI2017069
chr16_-_1968231 1.779 ENST00000443547.1
ENST00000293937.3
ENST00000454677.2
HS3ST6


heparan sulfate (glucosamine) 3-O-sulfotransferase 6


chr1_-_183622442 1.730 ENST00000308641.4
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr10_-_61513146 1.671 ENST00000430431.1
LINC00948
long intergenic non-protein coding RNA 948
chr1_+_60280458 1.650 ENST00000455990.1
ENST00000371208.3
HOOK1

hook microtubule-tethering protein 1

chr10_+_103348031 1.619 ENST00000370151.4
ENST00000370147.1
ENST00000370148.2
DPCD


deleted in primary ciliary dyskinesia homolog (mouse)


chr15_-_56757329 1.597 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr7_-_120497178 1.591 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12


tetraspanin 12


chr4_-_149363662 1.590 ENST00000355292.3
ENST00000358102.3
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr1_+_54359854 1.574 ENST00000361921.3
ENST00000322679.6
ENST00000532493.1
ENST00000525202.1
ENST00000524406.1
ENST00000388876.3
DIO1





deiodinase, iodothyronine, type I





chr1_-_57285038 1.563 ENST00000343433.6
C1orf168
chromosome 1 open reading frame 168
chr17_-_3867585 1.439 ENST00000359983.3
ENST00000352011.3
ENST00000397043.3
ENST00000397041.3
ENST00000397035.3
ENST00000397039.1
ENST00000309890.7
ATP2A3






ATPase, Ca++ transporting, ubiquitous






chr5_+_35617940 1.423 ENST00000282469.6
ENST00000509059.1
ENST00000356031.3
ENST00000510777.1
SPEF2



sperm flagellar 2



chr8_+_99076750 1.409 ENST00000545282.1
C8orf47
chromosome 8 open reading frame 47
chr8_+_99076509 1.406 ENST00000318528.3
C8orf47
chromosome 8 open reading frame 47
chr6_+_109169591 1.405 ENST00000368972.3
ENST00000392644.4
ARMC2

armadillo repeat containing 2

chr1_+_61542922 1.404 ENST00000407417.3
NFIA
nuclear factor I/A
chr10_-_61513201 1.399 ENST00000414264.1
ENST00000594536.1
LINC00948

long intergenic non-protein coding RNA 948

chr1_-_207119738 1.380 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr19_-_41388657 1.373 ENST00000301146.4
ENST00000291764.3
CYP2A7

cytochrome P450, family 2, subfamily A, polypeptide 7

chr2_-_154335300 1.360 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr17_+_39405939 1.354 ENST00000334109.2
KRTAP9-4
keratin associated protein 9-4
chr10_+_82116529 1.330 ENST00000411538.1
ENST00000256039.2
DYDC2

DPY30 domain containing 2

chr16_+_616995 1.329 ENST00000293874.2
ENST00000409527.2
ENST00000424439.2
ENST00000540585.1
PIGQ

NHLRC4

phosphatidylinositol glycan anchor biosynthesis, class Q

NHL repeat containing 4

chr12_-_68726052 1.329 ENST00000540418.1
ENST00000411698.2
ENST00000393543.3
ENST00000303145.7
MDM1



Mdm1 nuclear protein homolog (mouse)



chr15_-_42186248 1.297 ENST00000320955.6
SPTBN5
spectrin, beta, non-erythrocytic 5
chr2_-_239148599 1.264 ENST00000409182.1
ENST00000409002.3
ENST00000450098.1
ENST00000409356.1
ENST00000409160.3
ENST00000409574.1
ENST00000272937.5
HES6






hes family bHLH transcription factor 6






chr11_+_27062272 1.262 ENST00000529202.1
ENST00000533566.1
BBOX1

butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1

chr22_-_50970566 1.261 ENST00000405135.1
ENST00000401779.1
ODF3B

outer dense fiber of sperm tails 3B

chr1_-_60539405 1.237 ENST00000450089.2
C1orf87
chromosome 1 open reading frame 87
chr7_-_149194756 1.226 ENST00000461958.2
ZNF746
zinc finger protein 746
chr1_-_60539422 1.221 ENST00000371201.3
C1orf87
chromosome 1 open reading frame 87
chr20_-_33460621 1.210 ENST00000427420.1
ENST00000336431.5
GGT7

gamma-glutamyltransferase 7

chr7_+_29603394 1.209 ENST00000319694.2
PRR15
proline rich 15
chr17_-_39316983 1.186 ENST00000390661.3
KRTAP4-4
keratin associated protein 4-4
chr16_+_333152 1.183 ENST00000219406.6
ENST00000404312.1
ENST00000456379.1
PDIA2


protein disulfide isomerase family A, member 2


chr10_-_49459800 1.181 ENST00000305531.3
FRMPD2
FERM and PDZ domain containing 2
chr2_-_241500447 1.149 ENST00000536462.1
ENST00000405002.1
ENST00000441168.1
ENST00000403283.1
ANKMY1



ankyrin repeat and MYND domain containing 1



chr11_+_27062502 1.140 ENST00000263182.3
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr12_-_63328817 1.136 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr1_-_27339317 1.124 ENST00000289166.5
FAM46B
family with sequence similarity 46, member B
chr6_-_130031358 1.119 ENST00000368149.2
ARHGAP18
Rho GTPase activating protein 18
chr14_-_106642049 1.115 ENST00000390605.2
IGHV1-18
immunoglobulin heavy variable 1-18
chr8_-_103136481 1.104 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
NCALD






neurocalcin delta






chr11_+_27062860 1.074 ENST00000528583.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr17_-_39324424 1.064 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr10_+_94608245 1.062 ENST00000443748.2
ENST00000260762.6
EXOC6

exocyst complex component 6

chr16_+_4845379 1.062 ENST00000588606.1
ENST00000586005.1
SMIM22

small integral membrane protein 22

chr1_+_6615241 1.059 ENST00000333172.6
ENST00000328191.4
ENST00000351136.3
TAS1R1


taste receptor, type 1, member 1


chr2_-_238499303 1.013 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr14_+_75536280 1.001 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr9_-_126030817 0.989 ENST00000348403.5
ENST00000447404.2
ENST00000360998.3
STRBP


spermatid perinuclear RNA binding protein


chr2_-_68384603 0.985 ENST00000406245.2
ENST00000409164.1
ENST00000295121.6
WDR92


WD repeat domain 92


chr7_+_70597109 0.975 ENST00000333538.5
WBSCR17
Williams-Beuren syndrome chromosome region 17
chr11_+_1942580 0.967 ENST00000381558.1
TNNT3
troponin T type 3 (skeletal, fast)
chr15_+_27112948 0.962 ENST00000555060.1
GABRA5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr11_-_108464465 0.935 ENST00000525344.1
EXPH5
exophilin 5
chr2_-_238499337 0.933 ENST00000411462.1
ENST00000409822.1
RAB17

RAB17, member RAS oncogene family

chr19_+_17982747 0.929 ENST00000222248.3
SLC5A5
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr2_-_86564776 0.927 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1


receptor accessory protein 1


chr6_+_159290917 0.917 ENST00000367072.1
C6orf99
chromosome 6 open reading frame 99
chr3_+_111393659 0.916 ENST00000477665.1
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr14_+_77564440 0.910 ENST00000361786.2
ENST00000555437.1
ENST00000555611.1
ENST00000554658.1
KIAA1737



CLOCK-interacting pacemaker



chr15_-_65503801 0.889 ENST00000261883.4
CILP
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr21_+_42688657 0.884 ENST00000357985.2
FAM3B
family with sequence similarity 3, member B
chr13_+_113633620 0.876 ENST00000421756.1
ENST00000375601.3
MCF2L

MCF.2 cell line derived transforming sequence-like

chr11_-_108464321 0.874 ENST00000265843.4
EXPH5
exophilin 5
chr3_-_49459878 0.864 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
AMT


aminomethyltransferase


chr2_-_238499725 0.863 ENST00000264601.3
RAB17
RAB17, member RAS oncogene family
chr20_-_55841398 0.859 ENST00000395864.3
BMP7
bone morphogenetic protein 7
chr6_+_138483058 0.841 ENST00000251691.4
KIAA1244
KIAA1244
chr12_+_56661461 0.819 ENST00000546544.1
ENST00000553234.1
COQ10A

coenzyme Q10 homolog A (S. cerevisiae)

chr19_-_9092018 0.807 ENST00000397910.4
MUC16
mucin 16, cell surface associated
chr19_+_16771936 0.805 ENST00000187762.2
ENST00000599479.1
TMEM38A

transmembrane protein 38A

chr17_-_46035187 0.801 ENST00000300557.2
PRR15L
proline rich 15-like
chr3_-_49459865 0.800 ENST00000427987.1
AMT
aminomethyltransferase
chr5_+_176873446 0.798 ENST00000507881.1
PRR7
proline rich 7 (synaptic)
chr7_+_73624327 0.793 ENST00000361082.3
ENST00000275635.7
ENST00000470709.1
LAT2


linker for activation of T cells family, member 2


chrX_+_130192318 0.791 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr4_-_141348789 0.774 ENST00000414773.1
CLGN
calmegin
chr1_+_18807424 0.772 ENST00000400664.1
KLHDC7A
kelch domain containing 7A
chr18_-_45663666 0.768 ENST00000535628.2
ZBTB7C
zinc finger and BTB domain containing 7C
chr7_-_150675372 0.764 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr6_+_159291090 0.745 ENST00000367073.4
ENST00000608817.1
C6orf99

chromosome 6 open reading frame 99

chr4_+_6202448 0.743 ENST00000508601.1
RP11-586D19.1
RP11-586D19.1
chr8_-_110656995 0.742 ENST00000276646.9
ENST00000533065.1
SYBU

syntabulin (syntaxin-interacting)

chr2_-_238499131 0.741 ENST00000538644.1
RAB17
RAB17, member RAS oncogene family
chr17_-_6947225 0.739 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
SLC16A11


solute carrier family 16, member 11


chr4_+_184826418 0.726 ENST00000308497.4
ENST00000438269.1
STOX2

storkhead box 2

chr17_-_4545170 0.725 ENST00000576394.1
ENST00000574640.1
ALOX15

arachidonate 15-lipoxygenase

chr16_+_335680 0.722 ENST00000435833.1
PDIA2
protein disulfide isomerase family A, member 2
chr2_+_241631262 0.716 ENST00000337801.4
ENST00000429564.1
AQP12A

aquaporin 12A

chr11_+_86511549 0.713 ENST00000533902.2
PRSS23
protease, serine, 23
chr8_-_144691718 0.707 ENST00000377579.3
ENST00000433751.1
ENST00000220966.6
PYCRL


pyrroline-5-carboxylate reductase-like


chr17_-_72968809 0.705 ENST00000530857.1
ENST00000425042.2
HID1

HID1 domain containing

chr16_+_66400533 0.705 ENST00000341529.3
CDH5
cadherin 5, type 2 (vascular endothelium)
chr1_-_167906020 0.703 ENST00000458574.1
MPC2
mitochondrial pyruvate carrier 2
chr20_-_4982132 0.701 ENST00000338244.1
ENST00000424750.2
SLC23A2

solute carrier family 23 (ascorbic acid transporter), member 2

chr11_-_119252359 0.698 ENST00000455332.2
USP2
ubiquitin specific peptidase 2
chr14_-_67982146 0.697 ENST00000557779.1
ENST00000557006.1
TMEM229B

transmembrane protein 229B

chr5_+_35618058 0.689 ENST00000440995.2
SPEF2
sperm flagellar 2
chr2_+_191273052 0.684 ENST00000417958.1
ENST00000432036.1
ENST00000392328.1
MFSD6


major facilitator superfamily domain containing 6


chr16_+_83932684 0.680 ENST00000262430.4
MLYCD
malonyl-CoA decarboxylase
chr14_+_50999744 0.673 ENST00000441560.2
ATL1
atlastin GTPase 1
chr5_-_13944652 0.672 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr16_+_30205754 0.671 ENST00000354723.6
ENST00000355544.5
SULT1A3

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3

chr17_-_19265982 0.670 ENST00000268841.6
ENST00000261499.4
ENST00000575478.1
B9D1


B9 protein domain 1


chr5_+_169532896 0.669 ENST00000306268.6
ENST00000449804.2
FOXI1

forkhead box I1

chr14_-_67981916 0.667 ENST00000357461.2
TMEM229B
transmembrane protein 229B
chr15_+_50474385 0.666 ENST00000267842.5
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
chr14_+_105331596 0.664 ENST00000556508.1
ENST00000414716.3
ENST00000453495.1
ENST00000418279.1
CEP170B



centrosomal protein 170B



chr5_-_19988339 0.654 ENST00000382275.1
CDH18
cadherin 18, type 2
chr12_-_68726131 0.654 ENST00000430606.2
MDM1
Mdm1 nuclear protein homolog (mouse)
chr1_+_150254936 0.652 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51


chromosome 1 open reading frame 51


chr16_+_25228242 0.652 ENST00000219660.5
AQP8
aquaporin 8
chr11_+_67776012 0.650 ENST00000539229.1
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr17_+_73521763 0.646 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
LLGL2




lethal giant larvae homolog 2 (Drosophila)




chr11_+_27076764 0.645 ENST00000525090.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr8_-_17270809 0.644 ENST00000180173.5
ENST00000521857.1
MTMR7

myotubularin related protein 7

chr14_+_62584197 0.641 ENST00000334389.4
LINC00643
long intergenic non-protein coding RNA 643
chr21_-_46330545 0.640 ENST00000320216.6
ENST00000397852.1
ITGB2

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

chr11_-_33913708 0.639 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr10_+_12391481 0.633 ENST00000378847.3
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr15_+_50474412 0.632 ENST00000380902.4
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
chr15_+_74610894 0.632 ENST00000558821.1
ENST00000268082.4
CCDC33

coiled-coil domain containing 33

chr14_+_67999999 0.631 ENST00000329153.5
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr1_+_3614591 0.631 ENST00000378290.4
TP73
tumor protein p73
chr14_-_67981870 0.631 ENST00000555994.1
TMEM229B
transmembrane protein 229B
chr11_-_34533257 0.621 ENST00000312319.2
ELF5
E74-like factor 5 (ets domain transcription factor)
chr7_-_92855762 0.621 ENST00000453812.2
ENST00000394468.2
HEPACAM2

HEPACAM family member 2

chr16_+_691792 0.616 ENST00000307650.4
FAM195A
family with sequence similarity 195, member A
chr5_-_137071756 0.616 ENST00000394937.3
ENST00000309755.4
KLHL3

kelch-like family member 3

chr5_+_76114758 0.616 ENST00000514165.1
ENST00000296677.4
F2RL1

coagulation factor II (thrombin) receptor-like 1

chr2_-_241622278 0.612 ENST00000407834.3
AQP12B
aquaporin 12B
chr6_-_3227877 0.608 ENST00000259818.7
TUBB2B
tubulin, beta 2B class IIb
chr6_+_39760783 0.605 ENST00000398904.2
ENST00000538976.1
DAAM2

dishevelled associated activator of morphogenesis 2

chr19_-_18717627 0.601 ENST00000392386.3
CRLF1
cytokine receptor-like factor 1
chr17_-_8702667 0.598 ENST00000329805.4
MFSD6L
major facilitator superfamily domain containing 6-like
chr11_+_118868830 0.593 ENST00000334418.1
CCDC84
coiled-coil domain containing 84
chr13_+_33590553 0.591 ENST00000380099.3
KL
klotho
chr19_-_55686399 0.578 ENST00000587067.1
SYT5
synaptotagmin V
chr3_-_49851313 0.578 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr2_-_133427767 0.571 ENST00000397463.2
LYPD1
LY6/PLAUR domain containing 1
chr16_-_18468926 0.564 ENST00000545114.1
RP11-1212A22.4
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr2_-_31030277 0.564 ENST00000534090.2
ENST00000295055.8
CAPN13

calpain 13

chr12_+_108908962 0.562 ENST00000552695.1
ENST00000552758.1
ENST00000361549.2
FICD


FIC domain containing


chr15_-_83316254 0.561 ENST00000567678.1
ENST00000450751.2
CPEB1

cytoplasmic polyadenylation element binding protein 1

chr1_+_1115056 0.560 ENST00000379288.3
TTLL10
tubulin tyrosine ligase-like family, member 10
chr22_-_18923655 0.553 ENST00000438924.1
ENST00000457083.1
ENST00000420436.1
ENST00000334029.2
ENST00000357068.6
PRODH




proline dehydrogenase (oxidase) 1




chr16_+_19079311 0.547 ENST00000569127.1
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr16_-_3086927 0.547 ENST00000572449.1
CCDC64B
coiled-coil domain containing 64B
chr13_+_113656022 0.546 ENST00000423482.2
MCF2L
MCF.2 cell line derived transforming sequence-like
chr15_+_75639296 0.542 ENST00000564500.1
ENST00000355059.4
ENST00000566752.1
NEIL1


nei endonuclease VIII-like 1 (E. coli)


chr12_-_49488573 0.537 ENST00000266991.2
DHH
desert hedgehog
chr12_+_122667658 0.537 ENST00000339777.4
ENST00000425921.1
LRRC43

leucine rich repeat containing 43

chr1_+_16062820 0.536 ENST00000294454.5
SLC25A34
solute carrier family 25, member 34
chr7_+_30960915 0.535 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
AQP1


aquaporin 1 (Colton blood group)


chr18_-_47721447 0.534 ENST00000285039.7
MYO5B
myosin VB
chr22_+_41777927 0.534 ENST00000266304.4
TEF
thyrotrophic embryonic factor
chr10_+_12391685 0.534 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chrX_+_130192216 0.533 ENST00000276211.5
ARHGAP36
Rho GTPase activating protein 36
chr15_+_67547163 0.532 ENST00000335894.4
IQCH
IQ motif containing H
chr18_-_71959159 0.530 ENST00000494131.2
ENST00000397914.4
ENST00000340533.4
CYB5A


cytochrome b5 type A (microsomal)


chr4_+_129732467 0.529 ENST00000413543.2
PHF17
jade family PHD finger 1
chr17_-_4544960 0.525 ENST00000293761.3
ALOX15
arachidonate 15-lipoxygenase
chr1_-_85930823 0.522 ENST00000284031.8
ENST00000539042.1
DDAH1

dimethylarginine dimethylaminohydrolase 1

chr4_-_2420335 0.519 ENST00000503000.1
ZFYVE28
zinc finger, FYVE domain containing 28
chr13_-_70682590 0.518 ENST00000377844.4
KLHL1
kelch-like family member 1
chr20_-_55841662 0.518 ENST00000395863.3
ENST00000450594.2
BMP7

bone morphogenetic protein 7

chr2_-_71454185 0.516 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr17_-_56605341 0.511 ENST00000583114.1
SEPT4
septin 4
chr3_+_49059038 0.508 ENST00000451378.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr17_-_39306054 0.507 ENST00000343246.4
KRTAP4-5
keratin associated protein 4-5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 9.9 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
1.0 4.9 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.6 1.9 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.6 0.6 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.4 1.3 GO:2001301 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.4 2.9 GO:0098535 de novo centriole assembly(GO:0098535)
0.4 4.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.4 3.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.3 1.4 GO:0072134 nephrogenic mesenchyme morphogenesis(GO:0072134) allantois development(GO:1905069)
0.3 1.7 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.3 1.3 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.3 1.2 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.3 0.8 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.2 0.7 GO:0015993 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.2 0.9 GO:2000721 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.2 1.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.2 0.8 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.2 0.2 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.2 2.7 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.2 0.6 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.2 1.0 GO:0035377 transepithelial water transport(GO:0035377)
0.2 2.8 GO:0036159 inner dynein arm assembly(GO:0036159)
0.2 0.8 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.2 0.8 GO:0018032 protein amidation(GO:0018032)
0.2 2.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 0.7 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.2 1.2 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.2 0.5 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.2 0.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 2.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 0.2 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.2 0.6 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.4 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.1 1.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.5 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 0.7 GO:2001293 fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.1 0.4 GO:1900369 transcription, RNA-templated(GO:0001172) negative regulation of RNA interference(GO:1900369)
0.1 1.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 1.1 GO:0015705 iodide transport(GO:0015705)
0.1 1.0 GO:0021678 third ventricle development(GO:0021678)
0.1 1.5 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.2 GO:2000974 negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.1 0.3 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 1.6 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.2 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 0.1 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.1 0.6 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.7 GO:0001705 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.1 0.3 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.1 0.5 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.8 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 2.2 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.7 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.7 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.5 GO:0002877 acute inflammatory response to non-antigenic stimulus(GO:0002525) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.1 0.6 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.7 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.2 GO:0007497 posterior midgut development(GO:0007497)
0.1 0.8 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.1 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.1 0.4 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.6 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 1.5 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.5 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.3 GO:0036292 DNA rewinding(GO:0036292)
0.1 1.5 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.6 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.2 GO:0061325 cell proliferation involved in outflow tract morphogenesis(GO:0061325)
0.1 1.8 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.4 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.3 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.1 GO:0035106 operant conditioning(GO:0035106)
0.1 0.4 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 0.3 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 1.1 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.2 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.1 1.2 GO:0006527 arginine catabolic process(GO:0006527)
0.1 1.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.5 GO:0032439 endosome localization(GO:0032439)
0.1 0.2 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.2 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 1.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.3 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 1.4 GO:0072189 ureter development(GO:0072189)
0.1 0.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.2 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.1 0.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.5 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 1.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 0.2 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.3 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.3 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.2 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.3 GO:0060023 soft palate development(GO:0060023)
0.1 0.7 GO:0043297 apical junction assembly(GO:0043297)
0.1 0.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.7 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.4 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 1.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.7 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.3 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.0 0.2 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.7 GO:0045475 locomotor rhythm(GO:0045475)
0.0 1.0 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.5 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.5 GO:1901374 acetate ester transport(GO:1901374)
0.0 0.4 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.4 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.2 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.7 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.6 GO:0030238 male sex determination(GO:0030238)
0.0 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.4 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 3.3 GO:0007602 phototransduction(GO:0007602)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 1.0 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.4 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.0 1.2 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.2 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.3 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.1 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.1 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.3 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.9 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 2.1 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.0 0.5 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0090294 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.4 GO:0060539 diaphragm development(GO:0060539)
0.0 0.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.4 GO:0032310 prostaglandin secretion(GO:0032310)
0.0 0.5 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0070884 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016) regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.4 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.3 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.5 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.3 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.3 GO:0006477 protein sulfation(GO:0006477)
0.0 0.6 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.4 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 1.3 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.3 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.6 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.6 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.6 GO:0034332 adherens junction organization(GO:0034332)
0.0 0.7 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.2 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 1.6 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.3 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.0 GO:0034331 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217) zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 1.2 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.0 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.2 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.2 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.2 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.5 GO:0007628 adult walking behavior(GO:0007628)
0.0 0.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.8 GO:0051693 actin filament capping(GO:0051693)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.2 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 1.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 0.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.2 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.9 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0 0.0 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.5 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.1 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
0.0 0.2 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.0 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.0 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0001553 luteinization(GO:0001553)
0.0 0.0 GO:1904529 regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617)
0.0 0.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.1 GO:0045945 urea cycle(GO:0000050) urea metabolic process(GO:0019627) positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.8 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0019827 stem cell population maintenance(GO:0019827)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.4 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.0 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.3 GO:0006833 water transport(GO:0006833)
0.0 0.0 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0007567 parturition(GO:0007567)
0.0 0.4 GO:0033198 response to ATP(GO:0033198)
0.0 0.0 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.0 GO:0090191 negative regulation of mesonephros development(GO:0061218) negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.0 0.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.0 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.3 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.1 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.0 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.1 GO:0061025 membrane fusion(GO:0061025)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.0 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.2 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0098536 deuterosome(GO:0098536)
0.6 10.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 1.6 GO:0070695 FHF complex(GO:0070695)
0.2 0.6 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.2 0.8 GO:0060187 cell pole(GO:0060187)
0.2 0.6 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 0.9 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.2 0.8 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.7 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.4 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.1 0.6 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.3 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 1.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.5 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 1.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.7 GO:0035579 specific granule membrane(GO:0035579)
0.1 2.6 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 0.9 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.2 GO:0005608 laminin-3 complex(GO:0005608)
0.1 0.6 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.1 GO:0008091 spectrin(GO:0008091)
0.1 0.2 GO:0043159 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.1 1.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.7 GO:0036157 outer dynein arm(GO:0036157)
0.1 3.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.7 GO:0097433 dense body(GO:0097433)
0.1 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.3 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1 0.4 GO:1990393 3M complex(GO:1990393)
0.1 1.2 GO:0043235 receptor complex(GO:0043235)
0.1 0.5 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 1.3 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 3.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.5 GO:0097227 sperm annulus(GO:0097227)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 1.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.7 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 3.9 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.1 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.8 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.0 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.9 GO:0042629 mast cell granule(GO:0042629)
0.0 1.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.0 1.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.3 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.0 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.4 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 1.3 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 2.5 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.8 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 2.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.6 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.0 GO:1990745 EARP complex(GO:1990745)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.6 2.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.4 1.3 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.4 1.7 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.3 1.5 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.3 2.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.2 1.0 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.2 0.7 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.2 0.9 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 1.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 0.8 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.2 0.6 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 0.9 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 0.5 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.2 0.7 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.2 1.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 0.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.2 1.4 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.2 1.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.2 0.5 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 0.4 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.1 0.4 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.1 0.6 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 10.3 GO:0042805 actinin binding(GO:0042805)
0.1 1.9 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.4 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.6 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.4 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.1 0.5 GO:0008513 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.7 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.9 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 1.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.3 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.8 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 0.6 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.7 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.6 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.1 0.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.3 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 0.8 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.4 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.8 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.8 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.5 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.1 0.3 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.4 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.1 1.6 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 1.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.2 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 1.3 GO:0034452 dynactin binding(GO:0034452)
0.1 1.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.8 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.7 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 2.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 1.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 1.7 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.2 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.6 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 1.7 GO:0005112 Notch binding(GO:0005112)
0.1 0.4 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 1.3 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 1.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 2.0 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.2 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.1 0.3 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.3 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.7 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 3.5 GO:0019003 GDP binding(GO:0019003)
0.0 1.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0015250 water channel activity(GO:0015250)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 1.1 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 0.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 1.0 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.2 GO:0035473 lipase binding(GO:0035473) lipoprotein lipase activator activity(GO:0060230)
0.0 1.7 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.2 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.2 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0042007 interleukin-18 binding(GO:0042007)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 2.0 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.6 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.5 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 1.0 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.0 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 1.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.3 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.6 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.1 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.0 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.0 0.0 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 1.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.6 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 1.8 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.1 0.2 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 0.5 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.1 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 3.0 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.7 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.7 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.1 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 1.0 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 2.4 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.0 1.3 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.2 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 0.1 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 0.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.2 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.6 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.1 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 1.2 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.1 PID_ENDOTHELIN_PATHWAY Endothelins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.4 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.1 1.9 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 1.5 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.1 0.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.3 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.0 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.5 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 1.7 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.3 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.6 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.4 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.5 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.9 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.9 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.8 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.8 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.9 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME_AQUAPORIN_MEDIATED_TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.7 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.1 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.8 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.6 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.4 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 3.7 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.2 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.1 REACTOME_PROSTANOID_LIGAND_RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins