Motif ID: MIXL1_GSX1_BSX_MEOX2_LHX4

Z-value: 0.668


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
LHX4hg19_v2_chr1_+_180199393_1801994260.511.1e-02Click!
MEOX2hg19_v2_chr7_-_15726296_157264370.272.0e-01Click!
MIXL1hg19_v2_chr1_+_226411319_2264113660.213.2e-01Click!
GSX1hg19_v2_chr13_+_28366780_28366780-0.048.6e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of MIXL1_GSX1_BSX_MEOX2_LHX4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_152386732 4.792 ENST00000271835.3
CRNN
cornulin
chr4_+_69313145 3.402 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr17_-_38859996 1.820 ENST00000264651.2
KRT24
keratin 24
chr4_-_69111401 1.755 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr10_+_17270214 1.570 ENST00000544301.1
VIM
vimentin
chr12_+_107712173 1.449 ENST00000280758.5
ENST00000420571.2
BTBD11

BTB (POZ) domain containing 11

chr16_-_30122717 1.335 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr2_+_158114051 1.210 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr11_+_33061543 1.196 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1


t-complex 11, testis-specific-like 1


chr1_+_62439037 1.154 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr18_+_29027696 1.114 ENST00000257189.4
DSG3
desmoglein 3
chr3_-_108248169 1.100 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr12_-_30887948 1.070 ENST00000433722.2
CAPRIN2
caprin family member 2
chr2_-_208031943 1.039 ENST00000421199.1
ENST00000457962.1
KLF7

Kruppel-like factor 7 (ubiquitous)

chr7_-_28220354 1.016 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr6_-_66417107 0.967 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS



eyes shut homolog (Drosophila)



chr12_-_10978957 0.960 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr2_-_216003127 0.948 ENST00000412081.1
ENST00000272895.7
ABCA12

ATP-binding cassette, sub-family A (ABC1), member 12

chr9_+_12693336 0.902 ENST00000381137.2
ENST00000388918.5
TYRP1

tyrosinase-related protein 1

chr6_-_32157947 0.859 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr12_-_89746173 0.851 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr17_-_39150385 0.849 ENST00000391586.1
KRTAP3-3
keratin associated protein 3-3
chr12_-_25055177 0.849 ENST00000538118.1
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chrX_-_18690210 0.831 ENST00000379984.3
RS1
retinoschisin 1
chr17_-_64225508 0.829 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr2_-_40680578 0.808 ENST00000455476.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr17_-_57229155 0.808 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr5_+_31193847 0.794 ENST00000514738.1
ENST00000265071.2
CDH6

cadherin 6, type 2, K-cadherin (fetal kidney)

chr19_-_36001113 0.785 ENST00000434389.1
DMKN
dermokine
chr4_+_40198527 0.783 ENST00000381799.5
RHOH
ras homolog family member H
chr7_+_77428066 0.781 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2


putative homeodomain transcription factor 2


chr6_+_47666275 0.765 ENST00000327753.3
ENST00000283303.2
GPR115

G protein-coupled receptor 115

chr4_+_169418255 0.759 ENST00000505667.1
ENST00000511948.1
PALLD

palladin, cytoskeletal associated protein

chr11_-_121986923 0.718 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr3_+_121774202 0.711 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86



CD86 molecule



chr11_-_55703876 0.705 ENST00000301532.3
OR5I1
olfactory receptor, family 5, subfamily I, member 1
chr1_-_152131703 0.703 ENST00000316073.3
RPTN
repetin
chr6_+_34204642 0.702 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1




chr12_+_82347498 0.691 ENST00000550506.1
RP11-362A1.1
RP11-362A1.1
chr9_-_95166884 0.691 ENST00000375561.5
OGN
osteoglycin
chr3_+_186353756 0.690 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
FETUB


fetuin B


chr9_-_123639304 0.673 ENST00000436309.1
PHF19
PHD finger protein 19
chr3_-_33686925 0.663 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2


cytoplasmic linker associated protein 2


chr17_+_39261584 0.659 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr21_-_31864275 0.650 ENST00000334063.4
KRTAP19-3
keratin associated protein 19-3
chr7_+_77428149 0.649 ENST00000415251.2
ENST00000275575.7
PHTF2

putative homeodomain transcription factor 2

chr7_-_87342564 0.645 ENST00000265724.3
ENST00000416177.1
ABCB1

ATP-binding cassette, sub-family B (MDR/TAP), member 1

chr11_+_55578854 0.641 ENST00000333973.2
OR5L1
olfactory receptor, family 5, subfamily L, member 1
chr19_-_51522955 0.633 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr11_-_107729887 0.627 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr14_+_32798547 0.625 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6


A kinase (PRKA) anchor protein 6


chr2_-_158300556 0.625 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr5_-_39219641 0.609 ENST00000509072.1
ENST00000504542.1
ENST00000505428.1
ENST00000506557.1
FYB



FYN binding protein



chr9_-_95166841 0.607 ENST00000262551.4
OGN
osteoglycin
chr4_-_89951028 0.606 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr17_-_39211463 0.595 ENST00000542910.1
ENST00000398477.1
KRTAP2-2

keratin associated protein 2-2

chr2_+_68961934 0.590 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr1_+_84630645 0.582 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_+_26348246 0.574 ENST00000422622.2
SSPN
sarcospan
chr17_-_39254391 0.572 ENST00000333822.4
KRTAP4-8
keratin associated protein 4-8
chr8_+_22424551 0.572 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr12_+_81110684 0.569 ENST00000228644.3
MYF5
myogenic factor 5
chr6_+_151646800 0.568 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr3_-_149095652 0.567 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr2_+_68961905 0.561 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr14_+_32798462 0.555 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr11_-_111794446 0.555 ENST00000527950.1
CRYAB
crystallin, alpha B
chr2_-_166930131 0.553 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A



sodium channel, voltage-gated, type I, alpha subunit



chr2_+_210444142 0.547 ENST00000360351.4
ENST00000361559.4
MAP2

microtubule-associated protein 2

chr12_+_122688090 0.544 ENST00000324189.4
ENST00000546192.1
B3GNT4

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4

chr1_-_47407097 0.535 ENST00000457840.2
CYP4A11
cytochrome P450, family 4, subfamily A, polypeptide 11
chr4_-_57524061 0.534 ENST00000508121.1
HOPX
HOP homeobox
chr4_-_57547454 0.532 ENST00000556376.2
HOPX
HOP homeobox
chr4_-_143227088 0.527 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr4_-_57547870 0.525 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOPX



HOP homeobox



chr1_+_84609944 0.519 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_152974218 0.518 ENST00000331860.3
ENST00000443178.1
ENST00000295367.4
SPRR3


small proline-rich protein 3


chr3_+_148447887 0.517 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1


angiotensin II receptor, type 1


chr10_+_32873190 0.516 ENST00000375025.4
C10orf68
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr4_-_39979576 0.514 ENST00000303538.8
ENST00000503396.1
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr14_+_67291158 0.509 ENST00000555456.1
GPHN
gephyrin
chr9_+_125133315 0.507 ENST00000223423.4
ENST00000362012.2
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr21_-_42219065 0.505 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr17_-_9694614 0.502 ENST00000330255.5
ENST00000571134.1
DHRS7C

dehydrogenase/reductase (SDR family) member 7C

chr4_-_109541539 0.501 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1


RPL34 antisense RNA 1 (head to head)


chr12_-_48164812 0.501 ENST00000549151.1
ENST00000548919.1
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr1_-_28384598 0.501 ENST00000373864.1
EYA3
eyes absent homolog 3 (Drosophila)
chr2_-_70780770 0.501 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
TGFA


transforming growth factor, alpha


chr9_-_123639445 0.500 ENST00000312189.6
PHF19
PHD finger protein 19
chr19_-_51523412 0.493 ENST00000391805.1
ENST00000599077.1
KLK10

kallikrein-related peptidase 10

chr12_+_4385230 0.486 ENST00000536537.1
CCND2
cyclin D2
chr7_-_107443652 0.482 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3


solute carrier family 26 (anion exchanger), member 3


chr3_+_111393501 0.479 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr10_+_118187379 0.475 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chr10_+_18549645 0.473 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr10_-_14372870 0.470 ENST00000357447.2
FRMD4A
FERM domain containing 4A
chr4_+_66536248 0.462 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1

RP11-807H7.1

chr7_+_129984630 0.461 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
CPA5








carboxypeptidase A5








chr17_-_39274606 0.460 ENST00000391413.2
KRTAP4-11
keratin associated protein 4-11
chr2_+_90273679 0.452 ENST00000423080.2
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr1_-_205391178 0.450 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1



LEM domain containing 1



chr12_-_91398796 0.446 ENST00000261172.3
ENST00000551767.1
EPYC

epiphycan

chr15_+_63188009 0.446 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr17_-_39203519 0.445 ENST00000542137.1
ENST00000391419.3
KRTAP2-1

keratin associated protein 2-1

chr9_-_123639600 0.442 ENST00000373896.3
PHF19
PHD finger protein 19
chr14_-_64194745 0.435 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chr4_+_144354644 0.435 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr18_+_61445007 0.435 ENST00000447428.1
ENST00000546027.1
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr17_+_42785976 0.433 ENST00000393547.2
ENST00000398338.3
DBF4B

DBF4 homolog B (S. cerevisiae)

chr4_+_150999418 0.432 ENST00000296550.7
DCLK2
doublecortin-like kinase 2
chr16_-_20364030 0.430 ENST00000396134.2
ENST00000573567.1
ENST00000570757.1
ENST00000424589.1
ENST00000302509.4
ENST00000571174.1
ENST00000576688.1
UMOD






uromodulin






chr6_+_105404899 0.429 ENST00000345080.4
LIN28B
lin-28 homolog B (C. elegans)
chr13_-_36050819 0.428 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr11_-_7818520 0.425 ENST00000329434.2
OR5P2
olfactory receptor, family 5, subfamily P, member 2
chr2_-_89327228 0.422 ENST00000483158.1
IGKV3-11
immunoglobulin kappa variable 3-11
chr18_+_61554932 0.418 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2


serpin peptidase inhibitor, clade B (ovalbumin), member 2


chr4_-_20985632 0.416 ENST00000359001.5
KCNIP4
Kv channel interacting protein 4
chr15_-_64673630 0.416 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101


KIAA0101


chr2_-_55647057 0.413 ENST00000436346.1
CCDC88A
coiled-coil domain containing 88A
chr17_+_17082842 0.412 ENST00000579361.1
MPRIP
myosin phosphatase Rho interacting protein
chr5_+_115177178 0.411 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr19_-_51523275 0.410 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr2_-_68052694 0.409 ENST00000457448.1
AC010987.6
AC010987.6
chr17_+_59489112 0.408 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr5_+_53751445 0.405 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr14_-_72458326 0.403 ENST00000542853.1
AC005477.1
AC005477.1
chr4_+_70796784 0.400 ENST00000246891.4
ENST00000444405.3
CSN1S1

casein alpha s1

chr6_-_109777128 0.399 ENST00000358807.3
ENST00000358577.3
MICAL1

microtubule associated monooxygenase, calponin and LIM domain containing 1

chr6_-_31107127 0.397 ENST00000259845.4
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr12_+_8666126 0.396 ENST00000299665.2
CLEC4D
C-type lectin domain family 4, member D
chr10_+_6779326 0.395 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr19_+_7030589 0.394 ENST00000329753.5
MBD3L5
methyl-CpG binding domain protein 3-like 5
chr1_-_24469602 0.394 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr7_-_14029283 0.394 ENST00000433547.1
ENST00000405192.2
ETV1

ets variant 1

chr8_-_49833978 0.394 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr14_-_81425828 0.393 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
CEP128


centrosomal protein 128kDa


chr10_+_18629628 0.393 ENST00000377329.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr1_+_152881014 0.388 ENST00000368764.3
ENST00000392667.2
IVL

involucrin

chr8_+_7738726 0.386 ENST00000314357.3
DEFB103A
defensin, beta 103A
chr19_-_7040190 0.384 ENST00000381394.4
MBD3L4
methyl-CpG binding domain protein 3-like 4
chr13_+_109248500 0.382 ENST00000356711.2
MYO16
myosin XVI
chr3_+_130569429 0.378 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1



ATPase, Ca++ transporting, type 2C, member 1



chr9_+_470288 0.378 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr7_+_50348268 0.375 ENST00000438033.1
ENST00000439701.1
IKZF1

IKAROS family zinc finger 1 (Ikaros)

chr11_-_82708519 0.370 ENST00000534301.1
RAB30
RAB30, member RAS oncogene family
chr16_+_57279004 0.369 ENST00000219204.3
ARL2BP
ADP-ribosylation factor-like 2 binding protein
chr12_-_95510743 0.368 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr7_+_142378566 0.365 ENST00000390398.3
TRBV25-1
T cell receptor beta variable 25-1
chr2_+_90211643 0.364 ENST00000390277.2
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr4_-_139163491 0.363 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr2_-_70780572 0.362 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr2_+_169926047 0.362 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9


dehydrogenase/reductase (SDR family) member 9


chr3_+_98482175 0.360 ENST00000485391.1
ENST00000492254.1
ST3GAL6

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

chr17_+_7905912 0.356 ENST00000254854.4
GUCY2D
guanylate cyclase 2D, membrane (retina-specific)
chr8_-_101661887 0.352 ENST00000311812.2
SNX31
sorting nexin 31
chr1_-_67266939 0.350 ENST00000304526.2
INSL5
insulin-like 5
chr9_+_136501478 0.349 ENST00000393056.2
ENST00000263611.2
DBH

dopamine beta-hydroxylase (dopamine beta-monooxygenase)

chr15_+_75080883 0.349 ENST00000567571.1
CSK
c-src tyrosine kinase
chr15_-_31393910 0.348 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
TRPM1


transient receptor potential cation channel, subfamily M, member 1


chr20_+_30697298 0.346 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr4_-_76928641 0.344 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9
chr11_-_2323089 0.342 ENST00000456145.2
C11orf21
chromosome 11 open reading frame 21
chr2_+_90248739 0.342 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chrX_+_99839799 0.341 ENST00000373031.4
TNMD
tenomodulin
chr8_-_131399110 0.337 ENST00000521426.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr13_-_99667960 0.336 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr16_+_24741013 0.335 ENST00000315183.7
ENST00000395799.3
TNRC6A

trinucleotide repeat containing 6A

chr8_-_7287870 0.335 ENST00000318124.3
DEFB103B
defensin, beta 103B
chr11_-_13517565 0.334 ENST00000282091.1
ENST00000529816.1
PTH

parathyroid hormone

chr6_+_29429217 0.334 ENST00000396792.2
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr4_+_169013666 0.331 ENST00000359299.3
ANXA10
annexin A10
chr5_-_147162078 0.331 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2
chr12_+_18414446 0.326 ENST00000433979.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chr7_-_99277610 0.325 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5



cytochrome P450, family 3, subfamily A, polypeptide 5



chr2_-_214016314 0.325 ENST00000434687.1
ENST00000374319.4
IKZF2

IKAROS family zinc finger 2 (Helios)

chr13_+_32313658 0.324 ENST00000380314.1
ENST00000298386.2
RXFP2

relaxin/insulin-like family peptide receptor 2

chrX_-_106243451 0.321 ENST00000355610.4
ENST00000535534.1
MORC4

MORC family CW-type zinc finger 4

chr9_-_21351377 0.319 ENST00000380210.1
IFNA6
interferon, alpha 6
chr2_-_89442621 0.317 ENST00000492167.1
IGKV3-20
immunoglobulin kappa variable 3-20
chr21_-_31859755 0.317 ENST00000334055.3
KRTAP19-2
keratin associated protein 19-2
chr15_-_55562479 0.317 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr4_-_143226979 0.316 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr20_-_13971255 0.313 ENST00000284951.5
ENST00000378072.5
SEL1L2

sel-1 suppressor of lin-12-like 2 (C. elegans)

chr12_+_15699286 0.310 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO



protein tyrosine phosphatase, receptor type, O



chrX_+_13671225 0.310 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
TCEANC


transcription elongation factor A (SII) N-terminal and central domain containing


chr17_+_62223320 0.309 ENST00000580828.1
ENST00000582965.1
SNORA76

small nucleolar RNA, H/ACA box 76

chr10_+_69865866 0.309 ENST00000354393.2
MYPN
myopalladin
chr5_-_139726181 0.308 ENST00000507104.1
ENST00000230990.6
HBEGF

heparin-binding EGF-like growth factor

chr12_-_91546926 0.307 ENST00000550758.1
DCN
decorin
chr15_+_58430567 0.304 ENST00000536493.1
AQP9
aquaporin 9
chr1_+_156254070 0.304 ENST00000405535.2
ENST00000456810.1
TMEM79

transmembrane protein 79

chrX_-_153599578 0.303 ENST00000360319.4
ENST00000344736.4
FLNA

filamin A, alpha

chr5_+_147691979 0.303 ENST00000274565.4
SPINK7
serine peptidase inhibitor, Kazal type 7 (putative)
chr2_+_171034646 0.302 ENST00000409044.3
ENST00000408978.4
MYO3B

myosin IIIB

chr4_-_152149033 0.302 ENST00000514152.1
SH3D19
SH3 domain containing 19
chr3_+_130650738 0.302 ENST00000504612.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr21_+_17792672 0.302 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr12_+_26348429 0.302 ENST00000242729.2
SSPN
sarcospan
chr11_-_7847519 0.301 ENST00000328375.1
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chrX_+_70798261 0.301 ENST00000373696.3
ACRC
acidic repeat containing

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 0.7 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.2 0.9 GO:0035627 ceramide transport(GO:0035627)
0.2 0.6 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 1.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2 0.7 GO:0003095 pressure natriuresis(GO:0003095)
0.2 0.5 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.2 1.1 GO:0097338 response to clozapine(GO:0097338)
0.1 0.9 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.8 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.7 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 0.8 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.5 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.4 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.8 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 1.6 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 0.5 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.4 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.4 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.4 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 1.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.5 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.6 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 0.4 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 0.4 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 0.2 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.1 0.3 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.1 0.5 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.4 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.3 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.6 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.5 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1 0.4 GO:0002584 negative regulation of antigen processing and presentation of peptide antigen(GO:0002584)
0.1 1.0 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1 0.3 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.6 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.1 0.3 GO:0009822 alkaloid catabolic process(GO:0009822)
0.1 0.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.2 GO:0006710 androgen catabolic process(GO:0006710)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.3 GO:1904647 response to rotenone(GO:1904647)
0.1 0.2 GO:1904580 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.1 0.5 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.4 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 1.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.3 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.8 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.2 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.1 GO:1904956 Wnt signaling pathway involved in somitogenesis(GO:0090244) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 0.3 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 0.1 GO:0030805 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121)
0.1 0.8 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.3 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.2 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.3 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.3 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.4 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.1 0.1 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.1 0.3 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.3 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.2 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.1 0.3 GO:0042335 cuticle development(GO:0042335)
0.1 0.6 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.3 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.1 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.6 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 9.4 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.2 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.2 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.8 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.0 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0 0.6 GO:0019532 oxalate transport(GO:0019532)
0.0 0.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.2 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.5 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0048880 sensory system development(GO:0048880)
0.0 1.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.8 GO:0009642 response to light intensity(GO:0009642)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 1.1 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.6 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.4 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 1.0 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 1.1 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.4 GO:1904417 regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.0 0.2 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.9 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.6 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.5 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.1 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.8 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.3 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.5 GO:0046548 retinal rod cell development(GO:0046548)
0.0 1.0 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 3.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.1 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.1 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.0 0.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.5 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.2 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.1 GO:1903285 negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 1.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.3 GO:0002863 positive regulation of inflammatory response to antigenic stimulus(GO:0002863)
0.0 0.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0001878 response to yeast(GO:0001878) negative regulation by host of viral process(GO:0044793)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.1 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.0 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.0 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.1 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.1 GO:2000230 regulation of cholesterol transporter activity(GO:0060694) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) sensory perception of bitter taste(GO:0050913)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.2 GO:0098543 detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.0 0.0 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.2 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.4 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 4.5 GO:0009408 response to heat(GO:0009408)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 1.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636) negative regulation of hair follicle development(GO:0051799)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.3 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.2 GO:0071476 cellular hypotonic response(GO:0071476)
0.0 0.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.2 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.3 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.0 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354) thorax and anterior abdomen determination(GO:0007356)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.0 GO:1902523 regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.0 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.0 GO:0021764 amygdala development(GO:0021764)
0.0 0.1 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.4 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.8 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0001823 ureteric bud development(GO:0001657) mesonephros development(GO:0001823) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.0 0.0 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0046718 entry into host cell(GO:0030260) entry into host(GO:0044409) viral entry into host cell(GO:0046718) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.0 GO:1900003 regulation of serine-type endopeptidase activity(GO:1900003) regulation of serine-type peptidase activity(GO:1902571)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.2 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.1 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.0 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.1 GO:0042436 tryptophan catabolic process(GO:0006569) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.3 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0055091 negative regulation of phospholipase activity(GO:0010519) negative regulation of lipoprotein lipase activity(GO:0051005) phospholipid homeostasis(GO:0055091)
0.0 0.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.0 GO:0097106 postsynaptic density organization(GO:0097106)
0.0 0.0 GO:1903781 positive regulation of cardiac conduction(GO:1903781)
0.0 0.4 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.6 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.0 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.4 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.0 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.4 GO:0042339 keratan sulfate biosynthetic process(GO:0018146) keratan sulfate metabolic process(GO:0042339)
0.0 0.0 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.2 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.4 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.1 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.2 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.3 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0021942 regulation of definitive erythrocyte differentiation(GO:0010724) radial glia guided migration of Purkinje cell(GO:0021942)
0.0 1.1 GO:0006023 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.2 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.2 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.0 GO:0044179 cytolysis by symbiont of host cells(GO:0001897) hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) cytolysis in other organism involved in symbiotic interaction(GO:0051801) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.2 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.0 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.2 GO:0007625 grooming behavior(GO:0007625)
0.0 0.0 GO:1901078 regulation of relaxation of muscle(GO:1901077) negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.6 GO:0035094 response to nicotine(GO:0035094)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.0 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.3 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 0.5 GO:0031523 Myb complex(GO:0031523)
0.1 0.9 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.3 GO:0035841 new growing cell tip(GO:0035841)
0.1 0.3 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.1 1.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.3 GO:0005607 laminin-2 complex(GO:0005607)
0.1 0.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.2 GO:0043296 apical junction complex(GO:0043296)
0.1 0.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.8 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.2 GO:1990357 terminal web(GO:1990357)
0.1 2.9 GO:0001533 cornified envelope(GO:0001533)
0.1 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0005602 complement component C1 complex(GO:0005602)
0.0 1.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 8.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.9 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.7 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 1.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.1 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 0.6 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.8 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 1.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 1.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0031904 endosome lumen(GO:0031904)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.8 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0090543 ESCRT III complex(GO:0000815) Flemming body(GO:0090543)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.0 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.0 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.3 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.0 GO:0005776 autophagosome(GO:0005776)
0.0 0.7 GO:0016235 aggresome(GO:0016235)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:1990254 keratin filament binding(GO:1990254)
0.2 0.9 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.2 0.5 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.2 0.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 0.7 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.2 0.5 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.8 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.6 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.8 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.5 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 2.0 GO:0005549 odorant binding(GO:0005549)
0.1 0.6 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 0.8 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.8 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.9 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.3 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 1.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.4 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.1 0.3 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.2 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 0.2 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 0.4 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 1.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.2 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 0.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.2 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.3 GO:0008431 vitamin E binding(GO:0008431)
0.1 1.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.5 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.3 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.2 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.9 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.2 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.7 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.8 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0004802 transketolase activity(GO:0004802)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 1.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0005503 all-trans retinal binding(GO:0005503)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.5 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.2 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 1.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 2.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.0 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 6.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.0 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.5 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.0 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.1 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.4 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0071949 FAD binding(GO:0071949)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.3 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.0 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.0 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.5 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.3 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.3 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.9 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 1.2 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.1 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 2.5 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.2 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.4 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 1.2 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.5 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 0.6 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 0.3 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.0 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 6.4 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID_MYC_PATHWAY C-MYC pathway
0.0 0.5 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.3 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.7 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.7 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.8 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.5 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.1 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.5 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.3 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.0 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 1.0 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.6 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.9 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.0 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.6 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.9 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.9 REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 1.1 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 3.2 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.8 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.8 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.8 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.5 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME_OPSINS Genes involved in Opsins
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.8 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.1 REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.3 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 0.4 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.4 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.6 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 1.0 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.0 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.3 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.7 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.9 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.1 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 2.2 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE