Motif ID: NFATC1

Z-value: 1.112


Transcription factors associated with NFATC1:

Gene SymbolEntrez IDGene Name
NFATC1 ENSG00000131196.13 NFATC1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NFATC1hg19_v2_chr18_+_77155856_771559390.592.2e-03Click!


Activity profile for motif NFATC1.

activity profile for motif NFATC1


Sorted Z-values histogram for motif NFATC1

Sorted Z-values for motif NFATC1



Network of associatons between targets according to the STRING database.



First level regulatory network of NFATC1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_16085340 8.239 ENST00000508167.1
PROM1
prominin 1
chr4_-_16085314 8.219 ENST00000510224.1
PROM1
prominin 1
chr6_+_32407619 7.444 ENST00000395388.2
ENST00000374982.5
HLA-DRA

major histocompatibility complex, class II, DR alpha

chr4_-_100356291 5.970 ENST00000476959.1
ENST00000482593.1
ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

chr14_-_92413727 4.783 ENST00000267620.10
FBLN5
fibulin 5
chr1_-_161337662 4.419 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr6_-_32920794 4.121 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
HLA-DMA


XXbac-BPG181M17.5
major histocompatibility complex, class II, DM alpha


Uncharacterized protein
chr5_-_54468974 3.882 ENST00000381375.2
ENST00000296733.1
ENST00000322374.6
ENST00000334206.5
ENST00000331730.3
CDC20B




cell division cycle 20B




chr1_-_36906474 3.473 ENST00000433045.2
OSCP1
organic solute carrier partner 1
chr14_-_92413353 3.435 ENST00000556154.1
FBLN5
fibulin 5
chr4_-_38806404 3.398 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
TLR1


toll-like receptor 1


chr9_+_124922171 3.162 ENST00000373764.3
ENST00000536616.1
MORN5

MORN repeat containing 5

chr1_+_151682909 3.004 ENST00000326413.3
ENST00000442233.2
RIIAD1
AL589765.1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
Uncharacterized protein; cDNA FLJ36032 fis, clone TESTI2017069
chr1_+_36549676 2.969 ENST00000207457.3
TEKT2
tektin 2 (testicular)
chr5_+_140261703 2.921 ENST00000409494.1
ENST00000289272.2
PCDHA13

protocadherin alpha 13

chr10_+_94590910 2.864 ENST00000371547.4
EXOC6
exocyst complex component 6
chrX_-_99665262 2.851 ENST00000373034.4
ENST00000255531.7
PCDH19

protocadherin 19

chr10_+_115511213 2.817 ENST00000361048.1
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr7_+_6793740 2.782 ENST00000403107.1
ENST00000404077.1
ENST00000435395.1
ENST00000418406.1
RSPH10B2



radial spoke head 10 homolog B2 (Chlamydomonas)



chr7_-_6010263 2.746 ENST00000455618.2
ENST00000405415.1
ENST00000404406.1
ENST00000542644.1
RSPH10B



radial spoke head 10 homolog B (Chlamydomonas)



chr1_+_79115503 2.706 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44


interferon-induced protein 44


chr5_+_140207536 2.617 ENST00000529310.1
ENST00000527624.1
PCDHA6

protocadherin alpha 6

chr2_-_159237472 2.521 ENST00000409187.1
CCDC148
coiled-coil domain containing 148
chr1_+_61548374 2.482 ENST00000485903.2
ENST00000371185.2
ENST00000371184.2
NFIA


nuclear factor I/A


chr4_-_70518941 2.311 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1

UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus

UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr3_+_14444063 2.083 ENST00000454876.2
ENST00000360861.3
ENST00000416216.2
SLC6A6


solute carrier family 6 (neurotransmitter transporter), member 6


chr4_+_159443090 2.022 ENST00000343542.5
ENST00000470033.1
RXFP1

relaxin/insulin-like family peptide receptor 1

chr1_+_61547405 1.937 ENST00000371189.4
NFIA
nuclear factor I/A
chr4_+_41614909 1.869 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1


LIM and calponin homology domains 1


chr8_+_81397876 1.805 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr1_+_61548225 1.760 ENST00000371187.3
NFIA
nuclear factor I/A
chr1_+_46640750 1.756 ENST00000372003.1
TSPAN1
tetraspanin 1
chr9_+_27109392 1.698 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr4_-_168155417 1.599 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3


sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3


chr9_-_20622478 1.595 ENST00000355930.6
ENST00000380338.4
MLLT3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr11_+_36616044 1.578 ENST00000334307.5
ENST00000531554.1
ENST00000347206.4
ENST00000534635.1
ENST00000446510.2
ENST00000530697.1
ENST00000527108.1
C11orf74






chromosome 11 open reading frame 74






chr18_-_53177984 1.573 ENST00000543082.1
TCF4
transcription factor 4
chr11_-_102401469 1.529 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr12_-_91573132 1.506 ENST00000550563.1
ENST00000546370.1
DCN

decorin

chr14_-_89883412 1.503 ENST00000557258.1
FOXN3
forkhead box N3
chr1_-_151798546 1.496 ENST00000356728.6
RORC
RAR-related orphan receptor C
chrX_+_36254051 1.490 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr3_+_140981456 1.441 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr6_-_134495992 1.424 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
SGK1


serum/glucocorticoid regulated kinase 1


chr1_+_244214577 1.410 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chrX_+_9431324 1.403 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X





transducin (beta)-like 1X-linked





chr4_-_168155300 1.391 ENST00000541637.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr12_+_93771659 1.386 ENST00000337179.5
ENST00000415493.2
NUDT4

nudix (nucleoside diphosphate linked moiety X)-type motif 4

chr1_+_167298281 1.360 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr18_+_61575200 1.346 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr3_-_57530051 1.298 ENST00000311202.6
ENST00000351747.2
ENST00000495027.1
ENST00000389536.4
DNAH12



dynein, axonemal, heavy chain 12



chrY_+_15017624 1.297 ENST00000440554.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr4_-_168155169 1.280 ENST00000534949.1
ENST00000535728.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr3_+_69812877 1.246 ENST00000457080.1
ENST00000328528.6
MITF

microphthalmia-associated transcription factor

chr3_-_36986534 1.239 ENST00000429976.2
ENST00000301807.6
TRANK1

tetratricopeptide repeat and ankyrin repeat containing 1

chr8_-_72268968 1.202 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr11_-_75062829 1.168 ENST00000393505.4
ARRB1
arrestin, beta 1
chr4_-_168155577 1.163 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3





sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3





chr13_+_96085847 1.152 ENST00000376873.3
CLDN10
claudin 10
chr1_+_22351977 1.094 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
LINC00339


long intergenic non-protein coding RNA 339


chr13_-_62001982 1.092 ENST00000409186.1
PCDH20
protocadherin 20
chr2_-_157198860 1.048 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr6_-_119670919 1.033 ENST00000368468.3
MAN1A1
mannosidase, alpha, class 1A, member 1
chr18_+_77155856 1.025 ENST00000253506.5
ENST00000591814.1
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr18_-_53257027 1.022 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
TCF4


transcription factor 4


chr3_+_132316081 1.014 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr18_-_52989525 1.004 ENST00000457482.3
TCF4
transcription factor 4
chr8_-_140715294 0.999 ENST00000303015.1
ENST00000520439.1
KCNK9

potassium channel, subfamily K, member 9

chr1_+_235491714 0.988 ENST00000471812.1
ENST00000358966.2
ENST00000282841.5
ENST00000391855.2
GGPS1



geranylgeranyl diphosphate synthase 1



chr10_-_1246317 0.976 ENST00000381305.1
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr18_-_53089723 0.958 ENST00000561992.1
ENST00000562512.2
TCF4

transcription factor 4

chr10_-_1246300 0.951 ENST00000381310.3
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr1_+_180601139 0.943 ENST00000367590.4
ENST00000367589.3
XPR1

xenotropic and polytropic retrovirus receptor 1

chr9_-_215744 0.933 ENST00000382387.2
C9orf66
chromosome 9 open reading frame 66
chr9_-_73483958 0.861 ENST00000377101.1
ENST00000377106.1
ENST00000360823.2
ENST00000377105.1
TRPM3



transient receptor potential cation channel, subfamily M, member 3



chr20_+_43990576 0.856 ENST00000372727.1
ENST00000414310.1
SYS1

SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr11_-_75062730 0.856 ENST00000420843.2
ENST00000360025.3
ARRB1

arrestin, beta 1

chr5_-_111093759 0.847 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP



neuronal regeneration related protein



chr8_-_17555164 0.840 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr19_+_16059818 0.810 ENST00000322107.1
OR10H4
olfactory receptor, family 10, subfamily H, member 4
chr12_+_122181529 0.810 ENST00000541467.1
TMEM120B
transmembrane protein 120B
chrX_-_13835461 0.800 ENST00000316715.4
ENST00000356942.5
GPM6B

glycoprotein M6B

chr5_-_73937244 0.795 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1


ectodermal-neural cortex 1 (with BTB domain)


chr10_+_22610124 0.782 ENST00000376663.3
BMI1
BMI1 polycomb ring finger oncogene
chr6_-_39082922 0.777 ENST00000229903.4
SAYSD1
SAYSVFN motif domain containing 1
chr12_-_59314246 0.775 ENST00000320743.3
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr16_+_30968615 0.774 ENST00000262519.8
SETD1A
SET domain containing 1A
chr1_-_111743285 0.773 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chrX_-_84634737 0.760 ENST00000262753.4
POF1B
premature ovarian failure, 1B
chr18_-_52989217 0.718 ENST00000570287.2
TCF4
transcription factor 4
chrX_-_84634708 0.717 ENST00000373145.3
POF1B
premature ovarian failure, 1B
chrX_-_13835147 0.714 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr4_-_104021009 0.711 ENST00000509245.1
ENST00000296424.4
BDH2

3-hydroxybutyrate dehydrogenase, type 2

chr14_+_81421710 0.694 ENST00000342443.6
TSHR
thyroid stimulating hormone receptor
chr2_+_46926326 0.685 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr11_-_122930121 0.673 ENST00000524552.1
HSPA8
heat shock 70kDa protein 8
chr12_-_51422017 0.670 ENST00000394904.3
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chrX_-_10544942 0.654 ENST00000380779.1
MID1
midline 1 (Opitz/BBB syndrome)
chr14_+_93897272 0.652 ENST00000393151.2
UNC79
unc-79 homolog (C. elegans)
chrX_+_133941218 0.641 ENST00000370784.4
ENST00000370785.3
FAM122C

family with sequence similarity 122C

chr6_+_52051171 0.615 ENST00000340057.1
IL17A
interleukin 17A
chr14_+_81421921 0.615 ENST00000554263.1
ENST00000554435.1
TSHR

thyroid stimulating hormone receptor

chr12_+_109915179 0.610 ENST00000434735.2
UBE3B
ubiquitin protein ligase E3B
chr15_+_59730348 0.602 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A



family with sequence similarity 81, member A



chrX_-_46759138 0.599 ENST00000377879.3
CXorf31
chromosome X open reading frame 31
chr17_+_32582293 0.599 ENST00000580907.1
ENST00000225831.4
CCL2

chemokine (C-C motif) ligand 2

chr6_-_15663198 0.598 ENST00000338950.5
ENST00000511762.2
ENST00000355917.3
ENST00000344537.5
DTNBP1



dystrobrevin binding protein 1



chrX_+_105412290 0.585 ENST00000357175.2
ENST00000337685.2
MUM1L1

melanoma associated antigen (mutated) 1-like 1

chr2_-_97535708 0.582 ENST00000305476.5
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr17_-_35969409 0.580 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
SYNRG







synergin, gamma







chr3_-_65583561 0.572 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr19_+_35939154 0.569 ENST00000599180.2
FFAR2
free fatty acid receptor 2
chr8_-_124553437 0.568 ENST00000517956.1
ENST00000443022.2
FBXO32

F-box protein 32

chr7_-_25702669 0.567 ENST00000446840.1
AC003090.1
AC003090.1
chrX_+_133941250 0.559 ENST00000445123.1
FAM122C
family with sequence similarity 122C
chr8_+_86121448 0.557 ENST00000520225.1
E2F5
E2F transcription factor 5, p130-binding
chr10_-_72141330 0.556 ENST00000395011.1
ENST00000395010.1
LRRC20

leucine rich repeat containing 20

chr12_+_11802753 0.554 ENST00000396373.4
ETV6
ets variant 6
chr1_-_77685084 0.550 ENST00000370812.3
ENST00000359130.1
ENST00000445065.1
ENST00000370813.5
PIGK



phosphatidylinositol glycan anchor biosynthesis, class K



chr14_+_21538517 0.548 ENST00000298693.3
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr11_-_122929699 0.548 ENST00000526686.1
HSPA8
heat shock 70kDa protein 8
chr11_-_2182388 0.543 ENST00000397270.1
ENST00000421783.1
ENST00000397262.1
ENST00000250971.3
ENST00000381330.4
INS-IGF2
INS



INS-IGF2 readthrough
insulin



chr13_+_73629107 0.510 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chr9_+_35161998 0.498 ENST00000396787.1
ENST00000378495.3
ENST00000378496.4
UNC13B


unc-13 homolog B (C. elegans)


chr15_-_43785303 0.498 ENST00000382039.3
ENST00000450115.2
ENST00000382044.4
TP53BP1


tumor protein p53 binding protein 1


chr1_+_150254936 0.496 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51


chromosome 1 open reading frame 51


chr5_+_49962772 0.491 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8




poly (ADP-ribose) polymerase family, member 8




chr11_+_34642656 0.484 ENST00000257831.3
ENST00000450654.2
EHF

ets homologous factor

chr10_+_96698406 0.484 ENST00000260682.6
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr12_-_114843889 0.483 ENST00000405440.2
TBX5
T-box 5
chr16_+_15528332 0.477 ENST00000566490.1
C16orf45
chromosome 16 open reading frame 45
chr12_-_123921256 0.474 ENST00000280571.8
RILPL2
Rab interacting lysosomal protein-like 2
chr10_+_104535994 0.472 ENST00000369889.4
WBP1L
WW domain binding protein 1-like
chr13_-_67804445 0.471 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
PCDH9


protocadherin 9


chr2_+_86668464 0.470 ENST00000409064.1
KDM3A
lysine (K)-specific demethylase 3A
chr11_-_72492903 0.468 ENST00000537947.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr22_-_19512893 0.465 ENST00000403084.1
ENST00000413119.2
CLDN5

claudin 5

chr9_+_22446814 0.458 ENST00000325870.2
DMRTA1
DMRT-like family A1
chr16_-_21436459 0.457 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
NPIPB3


nuclear pore complex interacting protein family, member B3


chr8_+_38831683 0.449 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr7_-_105319536 0.447 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr2_-_46769694 0.444 ENST00000522587.1
ATP6V1E2
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chrX_+_76709648 0.443 ENST00000439435.1
FGF16
fibroblast growth factor 16
chr1_+_174846570 0.442 ENST00000392064.2
RABGAP1L
RAB GTPase activating protein 1-like
chr19_+_56459198 0.442 ENST00000291971.3
ENST00000590542.1
NLRP8

NLR family, pyrin domain containing 8

chr12_+_1929783 0.439 ENST00000535041.1
LRTM2
leucine-rich repeats and transmembrane domains 2
chr5_+_140787600 0.435 ENST00000520790.1
PCDHGB6
protocadherin gamma subfamily B, 6
chr16_-_55909255 0.432 ENST00000290567.9
CES5A
carboxylesterase 5A
chr1_+_158323755 0.432 ENST00000368157.1
ENST00000368156.1
ENST00000368155.3
ENST00000368154.1
ENST00000368160.3
ENST00000368161.3
CD1E





CD1e molecule





chr16_-_55909272 0.431 ENST00000319165.9
CES5A
carboxylesterase 5A
chr12_-_70093065 0.428 ENST00000553096.1
BEST3
bestrophin 3
chr3_-_182817367 0.427 ENST00000265594.4
MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr18_+_77155942 0.425 ENST00000397790.2
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr2_+_178977143 0.422 ENST00000286070.5
RBM45
RNA binding motif protein 45
chr12_+_1929421 0.420 ENST00000543818.1
LRTM2
leucine-rich repeats and transmembrane domains 2
chr4_+_146403912 0.415 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1


SMAD family member 1


chr1_-_91487013 0.414 ENST00000347275.5
ENST00000370440.1
ZNF644

zinc finger protein 644

chr2_-_145278475 0.412 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr3_-_79068594 0.410 ENST00000436010.2
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr1_+_44870866 0.406 ENST00000355387.2
ENST00000361799.2
RNF220

ring finger protein 220

chr5_-_88179302 0.406 ENST00000504921.2
MEF2C
myocyte enhancer factor 2C
chr8_+_145294015 0.406 ENST00000544576.1
MROH1
maestro heat-like repeat family member 1
chr19_+_10197463 0.405 ENST00000590378.1
ENST00000397881.3
C19orf66

chromosome 19 open reading frame 66

chr17_-_7120498 0.404 ENST00000485100.1
DLG4
discs, large homolog 4 (Drosophila)
chr9_-_35815013 0.403 ENST00000259667.5
HINT2
histidine triad nucleotide binding protein 2
chr14_-_23479331 0.402 ENST00000397377.1
ENST00000397379.3
ENST00000406429.2
ENST00000341470.4
ENST00000555998.1
ENST00000397376.2
ENST00000553675.1
ENST00000553931.1
ENST00000555575.1
ENST00000553958.1
ENST00000555098.1
ENST00000556419.1
ENST00000553606.1
ENST00000299088.6
ENST00000554179.1
ENST00000397382.4
C14orf93















chromosome 14 open reading frame 93















chr5_+_7869217 0.402 ENST00000264668.2
ENST00000514220.1
ENST00000341013.6
ENST00000440940.2
ENST00000502550.1
ENST00000506877.1
MTRR





5-methyltetrahydrofolate-homocysteine methyltransferase reductase





chr12_+_1929644 0.401 ENST00000299194.1
LRTM2
leucine-rich repeats and transmembrane domains 2
chr7_-_156803329 0.400 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chr14_-_35591433 0.399 ENST00000261475.5
ENST00000555644.1
PPP2R3C

protein phosphatase 2, regulatory subunit B'', gamma

chr16_-_55909211 0.398 ENST00000520435.1
CES5A
carboxylesterase 5A
chr10_-_92681033 0.396 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr11_-_129062093 0.395 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr3_-_185270383 0.391 ENST00000296252.4
LIPH
lipase, member H
chr7_-_100493744 0.385 ENST00000428317.1
ENST00000441605.1
ACHE

acetylcholinesterase (Yt blood group)

chr1_+_158323634 0.383 ENST00000452291.2
ENST00000368165.3
ENST00000368166.3
ENST00000368163.3
ENST00000368164.3
CD1E




CD1e molecule




chrX_-_24690771 0.380 ENST00000379145.1
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr1_+_174769006 0.377 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr16_-_30457048 0.377 ENST00000500504.2
ENST00000542752.1
SEPHS2

selenophosphate synthetase 2

chr16_-_4323015 0.374 ENST00000204517.6
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr6_+_10528560 0.370 ENST00000379597.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr5_-_7869108 0.368 ENST00000264669.5
ENST00000507572.1
ENST00000504695.1
FASTKD3


FAST kinase domains 3


chr8_+_7353368 0.364 ENST00000355602.2
DEFB107B
defensin, beta 107B
chr1_+_235492300 0.360 ENST00000476121.1
ENST00000497327.1
GGPS1

geranylgeranyl diphosphate synthase 1

chr3_+_98072698 0.360 ENST00000354924.2
OR5K4
olfactory receptor, family 5, subfamily K, member 4
chr5_+_140729649 0.360 ENST00000523390.1
PCDHGB1
protocadherin gamma subfamily B, 1
chr11_+_65190245 0.358 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1


nuclear paraspeckle assembly transcript 1 (non-protein coding)


chr11_-_68780824 0.357 ENST00000441623.1
ENST00000309099.6
MRGPRF

MAS-related GPR, member F

chr2_+_46926048 0.357 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr14_-_35873856 0.355 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA


nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha


chr17_-_39334460 0.351 ENST00000377726.2
KRTAP4-2
keratin associated protein 4-2
chr8_-_7673238 0.349 ENST00000335021.2
DEFB107A
defensin, beta 107A
chr15_+_100347228 0.349 ENST00000559714.1
ENST00000560059.1
CTD-2054N24.2

Uncharacterized protein

chr20_-_43589109 0.345 ENST00000372813.3
TOMM34
translocase of outer mitochondrial membrane 34
chr12_+_20968608 0.344 ENST00000553473.1
ENST00000554957.1
ENST00000381541.3
ENST00000540229.1
SLCO1B3
SLCO1B7
LST3

solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein

chr10_-_65028938 0.344 ENST00000402544.1
JMJD1C
jumonji domain containing 1C
chr14_+_51026743 0.342 ENST00000358385.6
ENST00000357032.3
ENST00000354525.4
ATL1


atlastin GTPase 1


chr4_+_86749045 0.342 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chr11_+_60970852 0.339 ENST00000325558.6
PGA3
pepsinogen 3, group I (pepsinogen A)
chr14_+_58894706 0.338 ENST00000261244.5
KIAA0586
KIAA0586

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 16.5 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
2.9 11.6 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
2.0 6.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.1 3.4 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.6 8.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 1.3 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.3 1.0 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3 7.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 1.2 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.2 0.9 GO:1904588 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.2 1.4 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2 3.0 GO:0036159 inner dynein arm assembly(GO:0036159)
0.2 0.6 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.2 0.6 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.2 1.7 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 1.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 0.5 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.2 2.0 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.2 1.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 0.8 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 0.3 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.2 3.9 GO:0072189 ureter development(GO:0072189)
0.1 1.0 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.4 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.1 0.7 GO:0015692 lead ion transport(GO:0015692)
0.1 2.4 GO:0007379 segment specification(GO:0007379)
0.1 0.4 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.4 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.6 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.5 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.6 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.5 GO:1900920 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 0.4 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.3 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) negative regulation of alkaline phosphatase activity(GO:0010693) uterine wall breakdown(GO:0042704) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.5 GO:2000302 regulation of synaptic vesicle priming(GO:0010807) positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1 0.3 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.1 2.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.5 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 0.9 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.5 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 1.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.6 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.7 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 0.5 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.8 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.8 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.4 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.2 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.1 0.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 1.5 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.2 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 0.1 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 0.5 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 0.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.5 GO:2000795 lung ciliated cell differentiation(GO:0061141) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.4 GO:0043418 homocysteine catabolic process(GO:0043418)
0.1 0.5 GO:0060179 male mating behavior(GO:0060179)
0.1 0.7 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.4 GO:2000546 positive regulation of fat cell proliferation(GO:0070346) positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.6 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 1.5 GO:0036315 cellular response to sterol(GO:0036315)
0.1 0.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.2 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.1 0.4 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.5 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.2 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 0.2 GO:2000566 positive regulation of thymocyte migration(GO:2000412) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.1 1.2 GO:0044849 estrous cycle(GO:0044849)
0.1 0.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.2 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 1.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.7 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.7 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 2.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 8.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.6 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.5 GO:0032782 bile acid secretion(GO:0032782)
0.0 1.1 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.2 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 1.5 GO:0072348 sulfur compound transport(GO:0072348)
0.0 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0071106 coenzyme A transport(GO:0015880) FAD transport(GO:0015883) coenzyme A transmembrane transport(GO:0035349) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.0 0.2 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.6 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.0 0.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.2 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.3 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.9 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:1902567 negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
0.0 1.8 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.0 1.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.7 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 3.3 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.8 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.4 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.8 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 4.8 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 1.5 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 1.4 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.0 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) regulation of telomere maintenance via semi-conservative replication(GO:0032213) negative regulation of telomere maintenance via semi-conservative replication(GO:0032214) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.2 GO:0006702 androgen biosynthetic process(GO:0006702)
0.0 1.6 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.3 GO:0036344 platelet morphogenesis(GO:0036344)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 1.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.0 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.6 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 0.3 GO:0009952 anterior/posterior pattern specification(GO:0009952)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.9 16.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.8 8.2 GO:0071953 elastic fiber(GO:0071953)
0.6 11.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.2 0.8 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1 0.7 GO:0070826 paraferritin complex(GO:0070826)
0.1 1.7 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.5 GO:0044305 calyx of Held(GO:0044305)
0.1 0.6 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 4.8 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.9 GO:0000145 exocyst(GO:0000145)
0.1 2.0 GO:0031143 pseudopodium(GO:0031143)
0.1 1.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.6 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 5.9 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 3.0 GO:0036126 sperm flagellum(GO:0036126)
0.0 3.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.4 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 1.1 GO:0030286 dynein complex(GO:0030286)
0.0 2.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.0 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.8 3.4 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.7 2.0 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.5 3.9 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.4 12.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.4 5.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 1.3 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2 0.7 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 17.0 GO:0042805 actinin binding(GO:0042805)
0.2 0.7 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 0.9 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 1.4 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.2 5.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 0.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 1.5 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.4 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.2 0.8 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.2 0.8 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.7 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.9 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.1 0.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.4 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 1.9 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 1.1 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1 0.5 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.2 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 0.5 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 0.4 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.6 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 2.1 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 1.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 2.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.0 1.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.8 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 1.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) FAD transmembrane transporter activity(GO:0015230) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 11.0 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 1.1 GO:0019956 chemokine binding(GO:0019956)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.4 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 1.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 1.4 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 2.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.3 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.7 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 3.4 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 6.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 8.1 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 2.0 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 5.9 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 3.7 PID_INSULIN_PATHWAY Insulin Pathway
0.0 1.1 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 2.0 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 1.7 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.8 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 1.2 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.9 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.8 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.3 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.3 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.7 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.2 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.4 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID_ATM_PATHWAY ATM pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.0 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.1 4.2 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.1 3.4 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 5.1 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 2.2 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.1 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.2 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.8 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 1.0 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.9 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 0.5 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.4 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 1.6 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.3 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.5 REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.8 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.9 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.0 0.4 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.3 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 2.9 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.5 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.6 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.4 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.6 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.6 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.2 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.6 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis