Motif ID: NKX1-2_RAX

Z-value: 0.551

Transcription factors associated with NKX1-2_RAX:

Gene SymbolEntrez IDGene Name
NKX1-2 ENSG00000229544.6 NKX1-2
RAX ENSG00000134438.9 RAX

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RAXhg19_v2_chr18_-_56940611_56940660-0.184.0e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of NKX1-2_RAX

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_35938674 5.596 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL



calcyphosine-like



chr12_+_7013897 3.589 ENST00000007969.8
ENST00000323702.5
LRRC23

leucine rich repeat containing 23

chr12_+_7014064 3.577 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr12_+_7014126 2.809 ENST00000415834.1
ENST00000436789.1
LRRC23

leucine rich repeat containing 23

chr12_-_25348007 2.173 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1






cancer susceptibility candidate 1






chr13_+_36050881 2.053 ENST00000537702.1
NBEA
neurobeachin
chr5_-_20575959 1.339 ENST00000507958.1
CDH18
cadherin 18, type 2
chr11_+_71900703 1.179 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr11_+_71900572 1.155 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr4_-_25865159 1.129 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr4_+_77356248 1.121 ENST00000296043.6
SHROOM3
shroom family member 3
chr11_-_63376013 0.826 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr4_-_141348789 0.783 ENST00000414773.1
CLGN
calmegin
chr2_+_217524323 0.745 ENST00000456764.1
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr16_-_28608364 0.740 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr1_+_201979645 0.672 ENST00000367284.5
ENST00000367283.3
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr16_-_28608424 0.653 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr14_+_74034310 0.609 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr6_+_26402465 0.601 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1





butyrophilin, subfamily 3, member A1





chr6_+_26440700 0.589 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3









butyrophilin, subfamily 3, member A3









chr4_-_74486109 0.506 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr7_+_70597109 0.495 ENST00000333538.5
WBSCR17
Williams-Beuren syndrome chromosome region 17
chrX_+_77166172 0.452 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A


ATPase, Cu++ transporting, alpha polypeptide


chr13_+_78315295 0.425 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr4_-_74486347 0.421 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr1_+_160370344 0.383 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr8_-_102803163 0.369 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD






neurocalcin delta






chr11_-_62521614 0.364 ENST00000527994.1
ENST00000394807.3
ZBTB3

zinc finger and BTB domain containing 3

chr3_-_105587879 0.364 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
CBLB


Cbl proto-oncogene B, E3 ubiquitin protein ligase


chr3_+_186560462 0.361 ENST00000412955.2
ADIPOQ
adiponectin, C1Q and collagen domain containing
chr3_+_186560476 0.360 ENST00000320741.2
ENST00000444204.2
ADIPOQ

adiponectin, C1Q and collagen domain containing

chr5_-_102898465 0.349 ENST00000507423.1
ENST00000230792.2
NUDT12

nudix (nucleoside diphosphate linked moiety X)-type motif 12

chr3_+_195447738 0.343 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20


mucin 20, cell surface associated


chr3_-_114790179 0.342 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr8_-_101571933 0.338 ENST00000520311.1
ANKRD46
ankyrin repeat domain 46
chr1_+_100818156 0.335 ENST00000336454.3
CDC14A
cell division cycle 14A
chr2_+_24714729 0.315 ENST00000406961.1
ENST00000405141.1
NCOA1

nuclear receptor coactivator 1

chr8_-_101571964 0.301 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
ANKRD46





ankyrin repeat domain 46





chr17_+_57232690 0.295 ENST00000262293.4
PRR11
proline rich 11
chr1_+_28261492 0.291 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chrX_+_77154935 0.281 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr1_-_190446759 0.278 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr3_-_11685345 0.270 ENST00000430365.2
VGLL4
vestigial like 4 (Drosophila)
chr16_-_28937027 0.262 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr20_+_43990576 0.243 ENST00000372727.1
ENST00000414310.1
SYS1

SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr7_+_138145076 0.238 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr20_-_29978286 0.237 ENST00000376315.2
DEFB119
defensin, beta 119
chr6_-_167040731 0.236 ENST00000265678.4
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr9_-_5339873 0.235 ENST00000223862.1
ENST00000223858.4
RLN1

relaxin 1

chr6_+_52442083 0.235 ENST00000606714.1
TRAM2-AS1
TRAM2 antisense RNA 1 (head to head)
chr4_-_66536196 0.234 ENST00000511294.1
EPHA5
EPH receptor A5
chr7_+_99717230 0.229 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr6_+_26402517 0.229 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr6_+_26365443 0.227 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2





butyrophilin, subfamily 3, member A2





chrX_-_13835147 0.220 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr6_+_26501449 0.208 ENST00000244513.6
BTN1A1
butyrophilin, subfamily 1, member A1
chr8_-_135522425 0.203 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr7_-_87856280 0.191 ENST00000490437.1
ENST00000431660.1
SRI

sorcin

chr4_-_74486217 0.190 ENST00000335049.5
ENST00000307439.5
RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chr7_-_87856303 0.184 ENST00000394641.3
SRI
sorcin
chr16_+_53133070 0.183 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr3_+_140396881 0.179 ENST00000286349.3
TRIM42
tripartite motif containing 42
chr1_+_100818009 0.177 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
CDC14A


cell division cycle 14A


chr2_-_239197201 0.176 ENST00000254658.3
PER2
period circadian clock 2
chr5_+_63802109 0.175 ENST00000334025.2
RGS7BP
regulator of G-protein signaling 7 binding protein
chr11_-_124981475 0.174 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
TMEM218











transmembrane protein 218











chr11_-_59383617 0.170 ENST00000263847.1
OSBP
oxysterol binding protein
chr7_-_86849883 0.165 ENST00000433078.1
TMEM243
transmembrane protein 243, mitochondrial
chr12_-_23737534 0.164 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chr2_-_239197238 0.158 ENST00000254657.3
PER2
period circadian clock 2
chr5_-_82969405 0.147 ENST00000510978.1
HAPLN1
hyaluronan and proteoglycan link protein 1
chr8_+_107738240 0.147 ENST00000449762.2
ENST00000297447.6
OXR1

oxidation resistance 1

chrX_+_130192318 0.140 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr9_-_3469181 0.135 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr17_-_41466555 0.135 ENST00000586231.1
LINC00910
long intergenic non-protein coding RNA 910
chr8_+_105235572 0.133 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr7_-_99717463 0.130 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr4_-_66536057 0.114 ENST00000273854.3
EPHA5
EPH receptor A5
chr1_-_151804314 0.109 ENST00000318247.6
RORC
RAR-related orphan receptor C
chr5_-_159546396 0.109 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP2A


PWWP domain containing 2A


chrX_-_8139308 0.105 ENST00000317103.4
VCX2
variable charge, X-linked 2
chr4_-_103748880 0.105 ENST00000453744.2
ENST00000349311.8
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr3_+_23851928 0.103 ENST00000467766.1
ENST00000424381.1
UBE2E1

ubiquitin-conjugating enzyme E2E 1

chrX_-_6453159 0.101 ENST00000381089.3
ENST00000398729.1
VCX3A

variable charge, X-linked 3A

chr12_-_74686314 0.097 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2


RP11-81H3.2


chr11_+_22689648 0.090 ENST00000278187.3
GAS2
growth arrest-specific 2
chr14_+_55493920 0.086 ENST00000395472.2
ENST00000555846.1
SOCS4

suppressor of cytokine signaling 4

chr14_+_55494323 0.086 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4
chr14_+_22670455 0.084 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr10_+_24755416 0.080 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217


KIAA1217


chr3_+_158519654 0.079 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1


major facilitator superfamily domain containing 1


chrM_+_9207 0.078 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr11_+_112047087 0.075 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
BCO2


beta-carotene oxygenase 2


chr8_+_107738343 0.073 ENST00000521592.1
OXR1
oxidation resistance 1
chr14_+_22465771 0.072 ENST00000390445.2
TRAV17
T cell receptor alpha variable 17
chr11_-_102651343 0.072 ENST00000279441.4
ENST00000539681.1
MMP10

matrix metallopeptidase 10 (stromelysin 2)

chr17_-_4938712 0.071 ENST00000254853.5
ENST00000424747.1
SLC52A1

solute carrier family 52 (riboflavin transporter), member 1

chr1_+_153747746 0.062 ENST00000368661.3
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr9_+_34646651 0.059 ENST00000378842.3
GALT
galactose-1-phosphate uridylyltransferase
chr11_-_13011081 0.059 ENST00000532541.1
ENST00000526388.1
ENST00000534477.1
ENST00000531402.1
ENST00000527945.1
ENST00000504230.2
LINC00958





long intergenic non-protein coding RNA 958





chr3_-_191000172 0.058 ENST00000427544.2
UTS2B
urotensin 2B
chr12_+_112279782 0.056 ENST00000550735.2
MAPKAPK5
mitogen-activated protein kinase-activated protein kinase 5
chr2_-_220264703 0.053 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP



aspartyl aminopeptidase



chr19_-_46285736 0.050 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK


dystrophia myotonica-protein kinase


chr12_-_112279694 0.050 ENST00000443596.1
ENST00000442119.1
MAPKAPK5-AS1

MAPKAPK5 antisense RNA 1

chrX_+_19362011 0.047 ENST00000379806.5
ENST00000545074.1
ENST00000540249.1
ENST00000423505.1
ENST00000417819.1
ENST00000422285.2
ENST00000355808.5
ENST00000379805.3
PDHA1







pyruvate dehydrogenase (lipoamide) alpha 1







chr7_-_7575477 0.045 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr4_+_110736659 0.045 ENST00000394631.3
ENST00000226796.6
GAR1

GAR1 ribonucleoprotein

chrX_-_21676442 0.041 ENST00000379499.2
KLHL34
kelch-like family member 34
chr17_-_10372875 0.040 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle
chr11_+_5710919 0.040 ENST00000379965.3
ENST00000425490.1
TRIM22

tripartite motif containing 22

chr7_-_99716952 0.036 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6










TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa










chr2_-_198540719 0.036 ENST00000295049.4
RFTN2
raftlin family member 2
chr2_-_89597542 0.035 ENST00000465170.1
IGKV1-37
immunoglobulin kappa variable 1-37 (non-functional)
chr9_+_34646624 0.034 ENST00000450095.2
ENST00000556278.1
GALT
GALT
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr6_+_154360357 0.028 ENST00000330432.7
ENST00000360422.4
OPRM1

opioid receptor, mu 1

chr10_-_92681033 0.027 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr1_-_92952433 0.026 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr1_+_43148059 0.025 ENST00000321358.7
ENST00000332220.6
YBX1

Y box binding protein 1

chr19_+_54641444 0.022 ENST00000221232.5
ENST00000358389.3
CNOT3

CCR4-NOT transcription complex, subunit 3

chr17_-_38821373 0.018 ENST00000394052.3
KRT222
keratin 222
chr10_-_114206649 0.017 ENST00000369404.3
ENST00000369405.3
ZDHHC6

zinc finger, DHHC-type containing 6

chr1_+_153746683 0.015 ENST00000271857.2
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr7_+_21582638 0.014 ENST00000409508.3
ENST00000328843.6
DNAH11

dynein, axonemal, heavy chain 11

chr8_+_9413410 0.012 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS


tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase


chr12_+_16500571 0.011 ENST00000543076.1
ENST00000396210.3
MGST1

microsomal glutathione S-transferase 1

chr17_-_39341594 0.009 ENST00000398472.1
KRTAP4-1
keratin associated protein 4-1
chr5_+_66300446 0.006 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr1_-_17766198 0.002 ENST00000375436.4
RCC2
regulator of chromosome condensation 2
chr2_-_86422095 0.000 ENST00000254636.5
IMMT
inner membrane protein, mitochondrial

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.2 0.7 GO:2000583 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.2 0.5 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.4 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.3 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.3 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 1.1 GO:0045176 apical protein localization(GO:0045176)
0.1 0.8 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.3 GO:1900920 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 1.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.7 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.4 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 1.1 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.5 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.0 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.7 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.6 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.1 0.4 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.5 GO:0060091 kinocilium(GO:0060091)
0.0 0.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0061714 folic acid receptor activity(GO:0061714)
0.2 1.4 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.2 0.8 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 0.5 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.7 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.8 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 1.3 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA