Motif ID: NR0B1

Z-value: 0.596


Transcription factors associated with NR0B1:

Gene SymbolEntrez IDGene Name
NR0B1 ENSG00000169297.6 NR0B1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR0B1hg19_v2_chrX_-_30327495_30327509,
hg19_v2_chrX_-_30326445_30326605
-0.424.2e-02Click!


Activity profile for motif NR0B1.

activity profile for motif NR0B1


Sorted Z-values histogram for motif NR0B1

Sorted Z-values for motif NR0B1



Network of associatons between targets according to the STRING database.



First level regulatory network of NR0B1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_29595779 0.726 ENST00000355973.3
ENST00000377012.4
GABBR1

gamma-aminobutyric acid (GABA) B receptor, 1

chr12_+_50355647 0.684 ENST00000293599.6
AQP5
aquaporin 5
chrX_+_130192318 0.512 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chrX_+_130192216 0.449 ENST00000276211.5
ARHGAP36
Rho GTPase activating protein 36
chr1_-_46598371 0.420 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
PIK3R3




phosphoinositide-3-kinase, regulatory subunit 3 (gamma)




chr1_-_46598284 0.394 ENST00000423209.1
ENST00000262741.5
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr2_+_234545148 0.370 ENST00000373445.1
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr8_-_100025238 0.362 ENST00000521696.1
RP11-410L14.2
RP11-410L14.2
chr1_+_26146397 0.355 ENST00000374303.2
ENST00000533762.1
ENST00000529116.1
ENST00000474295.1
ENST00000488327.2
ENST00000472643.1
ENST00000526894.1
ENST00000524618.1
ENST00000374307.5
MTFR1L








mitochondrial fission regulator 1-like








chrX_-_128788914 0.325 ENST00000429967.1
ENST00000307484.6
APLN

apelin

chr3_-_183979251 0.313 ENST00000296238.3
CAMK2N2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr1_-_40098672 0.313 ENST00000535435.1
HEYL
hes-related family bHLH transcription factor with YRPW motif-like
chr1_+_26146674 0.308 ENST00000525713.1
ENST00000374301.3
MTFR1L

mitochondrial fission regulator 1-like

chr20_-_3996165 0.302 ENST00000545616.2
ENST00000358395.6
RNF24

ring finger protein 24

chr1_-_223537401 0.299 ENST00000343846.3
ENST00000454695.2
ENST00000484758.2
SUSD4


sushi domain containing 4


chr7_+_89841024 0.292 ENST00000394626.1
STEAP2
STEAP family member 2, metalloreductase
chr5_+_110559603 0.288 ENST00000512453.1
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr7_+_89841144 0.287 ENST00000394622.2
ENST00000394632.1
ENST00000426158.1
ENST00000394621.2
ENST00000402625.2
STEAP2




STEAP family member 2, metalloreductase




chr19_-_49576198 0.281 ENST00000221444.1
KCNA7
potassium voltage-gated channel, shaker-related subfamily, member 7
chr14_-_61190754 0.279 ENST00000216513.4
SIX4
SIX homeobox 4
chr4_-_151936865 0.267 ENST00000535741.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr7_-_8302298 0.264 ENST00000446305.1
ICA1
islet cell autoantigen 1, 69kDa
chr1_-_223536679 0.249 ENST00000608996.1
SUSD4
sushi domain containing 4
chr5_+_159343688 0.248 ENST00000306675.3
ADRA1B
adrenoceptor alpha 1B
chr10_-_13570533 0.247 ENST00000396900.2
ENST00000396898.2
BEND7

BEN domain containing 7

chr12_+_56661461 0.227 ENST00000546544.1
ENST00000553234.1
COQ10A

coenzyme Q10 homolog A (S. cerevisiae)

chr5_-_42811986 0.227 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1


selenoprotein P, plasma, 1


chr10_-_123687431 0.223 ENST00000423243.1
ATE1
arginyltransferase 1
chr7_+_94139105 0.222 ENST00000297273.4
CASD1
CAS1 domain containing 1
chr3_-_45957088 0.219 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr7_-_100487280 0.217 ENST00000388761.2
UFSP1
UFM1-specific peptidase 1 (non-functional)
chr3_+_88108381 0.216 ENST00000473136.1
RP11-159G9.5
Uncharacterized protein
chr14_+_59104741 0.213 ENST00000395153.3
ENST00000335867.4
DACT1

dishevelled-binding antagonist of beta-catenin 1

chr9_+_71320557 0.212 ENST00000541509.1
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr15_-_82338460 0.211 ENST00000558133.1
ENST00000329713.4
MEX3B

mex-3 RNA binding family member B

chr1_-_23810664 0.210 ENST00000336689.3
ENST00000437606.2
ASAP3

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

chr1_+_180601139 0.210 ENST00000367590.4
ENST00000367589.3
XPR1

xenotropic and polytropic retrovirus receptor 1

chr17_-_42277203 0.207 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr2_+_170683942 0.207 ENST00000272793.5
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr15_+_74422585 0.207 ENST00000561740.1
ENST00000435464.1
ENST00000453268.2
ISLR2


immunoglobulin superfamily containing leucine-rich repeat 2


chr2_+_234545092 0.206 ENST00000344644.5
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr2_+_170683979 0.205 ENST00000418381.1
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chrX_-_112084043 0.204 ENST00000304758.1
AMOT
angiomotin
chr20_-_35807970 0.200 ENST00000400440.2
ENST00000421643.1
MROH8

maestro heat-like repeat family member 8

chr18_-_5396271 0.197 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr12_+_41086297 0.195 ENST00000551295.2
CNTN1
contactin 1
chr3_+_128720424 0.191 ENST00000480450.1
ENST00000436022.2
EFCC1

EF-hand and coiled-coil domain containing 1

chr12_+_12764773 0.189 ENST00000228865.2
CREBL2
cAMP responsive element binding protein-like 2
chr16_+_4845379 0.188 ENST00000588606.1
ENST00000586005.1
SMIM22

small integral membrane protein 22

chr17_-_7155274 0.185 ENST00000318988.6
ENST00000575783.1
ENST00000573600.1
CTDNEP1


CTD nuclear envelope phosphatase 1


chr9_+_71320596 0.184 ENST00000265382.3
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr13_+_33590553 0.180 ENST00000380099.3
KL
klotho
chr17_+_62075703 0.179 ENST00000577953.1
ENST00000582540.1
ENST00000579184.1
ENST00000425164.3
ENST00000412177.1
ENST00000539996.1
ENST00000583891.1
ENST00000580752.1
C17orf72







chromosome 17 open reading frame 72







chr5_+_169780485 0.173 ENST00000377360.4
KCNIP1
Kv channel interacting protein 1
chr5_-_137368708 0.170 ENST00000033079.3
FAM13B
family with sequence similarity 13, member B
chr14_+_57046530 0.166 ENST00000536419.1
ENST00000538838.1
TMEM260

transmembrane protein 260

chr2_+_209131059 0.161 ENST00000422495.1
ENST00000452564.1
PIKFYVE

phosphoinositide kinase, FYVE finger containing

chr1_+_153700518 0.158 ENST00000318967.2
ENST00000456435.1
ENST00000435409.2
INTS3


integrator complex subunit 3


chr22_-_36903101 0.158 ENST00000397224.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr5_+_111496631 0.157 ENST00000508590.1
EPB41L4A-AS1
EPB41L4A antisense RNA 1
chr13_-_52027134 0.153 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6




integrator complex subunit 6




chr12_-_80084333 0.152 ENST00000552637.1
PAWR
PRKC, apoptosis, WT1, regulator
chr5_+_112312416 0.151 ENST00000389063.2
DCP2
decapping mRNA 2
chr10_-_61666267 0.148 ENST00000263102.6
CCDC6
coiled-coil domain containing 6
chr3_+_181429704 0.148 ENST00000431565.2
ENST00000325404.1
SOX2

SRY (sex determining region Y)-box 2

chr2_-_152955537 0.147 ENST00000201943.5
ENST00000539935.1
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr12_+_56661033 0.145 ENST00000433805.2
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr1_+_21835858 0.144 ENST00000539907.1
ENST00000540617.1
ENST00000374840.3
ALPL


alkaline phosphatase, liver/bone/kidney


chr19_+_49661037 0.139 ENST00000427978.2
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr11_+_61447845 0.139 ENST00000257215.5
DAGLA
diacylglycerol lipase, alpha
chr8_-_142011036 0.139 ENST00000520892.1
PTK2
protein tyrosine kinase 2
chr8_-_102217796 0.136 ENST00000519744.1
ENST00000311212.4
ENST00000521272.1
ENST00000519882.1
ZNF706



zinc finger protein 706



chr6_+_43149903 0.136 ENST00000252050.4
ENST00000354495.3
ENST00000372647.2
CUL9


cullin 9


chr19_-_36523709 0.134 ENST00000592017.1
ENST00000360535.4
CLIP3

CAP-GLY domain containing linker protein 3

chr16_-_28937027 0.134 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr22_-_39639021 0.131 ENST00000455790.1
PDGFB
platelet-derived growth factor beta polypeptide
chr6_+_56954867 0.128 ENST00000370708.4
ENST00000370702.1
ZNF451

zinc finger protein 451

chr5_+_38258511 0.127 ENST00000354891.3
ENST00000322350.5
EGFLAM

EGF-like, fibronectin type III and laminin G domains

chr14_+_57046500 0.126 ENST00000261556.6
TMEM260
transmembrane protein 260
chr10_-_128077024 0.126 ENST00000368679.4
ENST00000368676.4
ENST00000448723.1
ADAM12


ADAM metallopeptidase domain 12


chr10_+_38299546 0.126 ENST00000374618.3
ENST00000432900.2
ENST00000458705.2
ENST00000469037.2
ZNF33A



zinc finger protein 33A



chr2_+_30454390 0.125 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
LBH


limb bud and heart development


chr6_+_137243373 0.121 ENST00000331858.4
SLC35D3
solute carrier family 35, member D3
chr4_-_168155417 0.121 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3


sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3


chr2_+_27301435 0.120 ENST00000380320.4
EMILIN1
elastin microfibril interfacer 1
chr1_-_19229014 0.120 ENST00000538839.1
ENST00000290597.5
ALDH4A1

aldehyde dehydrogenase 4 family, member A1

chr14_+_96968707 0.120 ENST00000216277.8
ENST00000557320.1
ENST00000557471.1
PAPOLA


poly(A) polymerase alpha


chr10_-_79397316 0.113 ENST00000372421.5
ENST00000457953.1
KCNMA1

potassium large conductance calcium-activated channel, subfamily M, alpha member 1

chr1_-_159915386 0.112 ENST00000361509.3
ENST00000368094.1
IGSF9

immunoglobulin superfamily, member 9

chr12_+_65672702 0.111 ENST00000538045.1
ENST00000535239.1
MSRB3

methionine sulfoxide reductase B3

chr10_+_5726764 0.111 ENST00000328090.5
ENST00000496681.1
FAM208B

family with sequence similarity 208, member B

chr1_-_16302565 0.109 ENST00000537142.1
ENST00000448462.2
ZBTB17

zinc finger and BTB domain containing 17

chr5_+_175792459 0.109 ENST00000310389.5
ARL10
ADP-ribosylation factor-like 10
chr4_-_175750364 0.108 ENST00000340217.5
ENST00000274093.3
GLRA3

glycine receptor, alpha 3

chr17_+_36858694 0.108 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr15_-_65067773 0.106 ENST00000300069.4
RBPMS2
RNA binding protein with multiple splicing 2
chr18_+_29672573 0.105 ENST00000578107.1
ENST00000257190.5
ENST00000580499.1
RNF138


ring finger protein 138, E3 ubiquitin protein ligase


chr10_+_112404132 0.105 ENST00000369519.3
RBM20
RNA binding motif protein 20
chr1_-_32801825 0.104 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr5_+_67511524 0.103 ENST00000521381.1
ENST00000521657.1
PIK3R1

phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

chr2_+_54342574 0.102 ENST00000303536.4
ENST00000394666.3
ACYP2

acylphosphatase 2, muscle type

chr14_-_23822061 0.102 ENST00000397260.3
SLC22A17
solute carrier family 22, member 17
chr11_+_77300669 0.101 ENST00000313578.3
AQP11
aquaporin 11
chr12_-_112037136 0.100 ENST00000608853.1
ATXN2
ataxin 2
chr12_+_56473628 0.099 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3


v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3


chr16_-_279405 0.099 ENST00000430864.1
ENST00000293872.8
ENST00000337351.4
ENST00000397783.1
LUC7L



LUC7-like (S. cerevisiae)



chr7_-_48068699 0.098 ENST00000412142.1
ENST00000395572.2
SUN3

Sad1 and UNC84 domain containing 3

chr6_-_26108355 0.098 ENST00000338379.4
HIST1H1T
histone cluster 1, H1t
chr19_+_49660997 0.098 ENST00000598691.1
ENST00000252826.5
TRPM4

transient receptor potential cation channel, subfamily M, member 4

chr1_-_16302608 0.097 ENST00000375743.4
ENST00000375733.2
ZBTB17

zinc finger and BTB domain containing 17

chr5_+_112312399 0.097 ENST00000515408.1
ENST00000513585.1
DCP2

decapping mRNA 2

chr1_+_211433275 0.097 ENST00000367005.4
RCOR3
REST corepressor 3
chr3_-_88108192 0.097 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr5_-_107717058 0.097 ENST00000359660.5
FBXL17
F-box and leucine-rich repeat protein 17
chr20_-_62284766 0.096 ENST00000370053.1
STMN3
stathmin-like 3
chr7_-_48068671 0.094 ENST00000297325.4
SUN3
Sad1 and UNC84 domain containing 3
chr5_+_111496554 0.094 ENST00000442823.2
EPB41L4A-AS1
EPB41L4A antisense RNA 1
chr3_+_140770183 0.094 ENST00000310546.2
SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr16_+_15528332 0.093 ENST00000566490.1
C16orf45
chromosome 16 open reading frame 45
chr15_-_72490114 0.093 ENST00000309731.7
GRAMD2
GRAM domain containing 2
chr12_+_7342441 0.092 ENST00000412720.2
ENST00000396637.3
PEX5

peroxisomal biogenesis factor 5

chr7_-_48068643 0.092 ENST00000453192.2
SUN3
Sad1 and UNC84 domain containing 3
chr5_-_81046922 0.092 ENST00000514493.1
ENST00000320672.4
SSBP2

single-stranded DNA binding protein 2

chr22_-_38794490 0.092 ENST00000400206.2
CSNK1E
casein kinase 1, epsilon
chr4_+_38665810 0.091 ENST00000261438.5
ENST00000514033.1
KLF3

Kruppel-like factor 3 (basic)

chr12_+_7342271 0.090 ENST00000434354.2
ENST00000544456.1
ENST00000545574.1
ENST00000420616.2
PEX5



peroxisomal biogenesis factor 5



chr2_+_97203082 0.090 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr14_-_23822080 0.089 ENST00000397267.1
ENST00000354772.3
SLC22A17

solute carrier family 22, member 17

chr12_+_58005204 0.089 ENST00000286494.4
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr2_+_54342533 0.088 ENST00000406041.1
ACYP2
acylphosphatase 2, muscle type
chr7_-_155604967 0.088 ENST00000297261.2
SHH
sonic hedgehog
chr8_+_22132847 0.088 ENST00000521356.1
PIWIL2
piwi-like RNA-mediated gene silencing 2
chr12_+_69864129 0.086 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
FRS2









fibroblast growth factor receptor substrate 2









chr2_-_74405929 0.083 ENST00000396049.4
MOB1A
MOB kinase activator 1A
chr7_+_99156314 0.082 ENST00000425063.1
ENST00000493277.1
ZNF655

zinc finger protein 655

chr2_+_54198210 0.081 ENST00000607452.1
ENST00000422521.2
ACYP2

acylphosphatase 2, muscle type

chr19_-_36523529 0.081 ENST00000593074.1
CLIP3
CAP-GLY domain containing linker protein 3
chr7_+_26438187 0.081 ENST00000439120.1
ENST00000430548.1
ENST00000421862.1
ENST00000449537.1
ENST00000420774.1
ENST00000418758.2
AC004540.5





AC004540.5





chr17_+_29421900 0.081 ENST00000358273.4
ENST00000356175.3
NF1

neurofibromin 1

chr17_-_77770830 0.080 ENST00000269385.4
CBX8
chromobox homolog 8
chr2_+_191513789 0.080 ENST00000409581.1
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr9_+_131451480 0.079 ENST00000322030.8
SET
SET nuclear oncogene
chr14_+_29236269 0.079 ENST00000313071.4
FOXG1
forkhead box G1
chr12_+_56473939 0.079 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr6_+_33387830 0.078 ENST00000293748.5
SYNGAP1
synaptic Ras GTPase activating protein 1
chr10_-_21463116 0.078 ENST00000417816.2
NEBL
nebulette
chr12_-_45270077 0.077 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2


NEL-like 2 (chicken)


chr4_-_151936416 0.077 ENST00000510413.1
ENST00000507224.1
LRBA

LPS-responsive vesicle trafficking, beach and anchor containing

chr14_-_89021077 0.076 ENST00000556564.1
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr22_+_29279552 0.076 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chr2_-_43823093 0.074 ENST00000405006.4
THADA
thyroid adenoma associated
chrX_+_106163626 0.073 ENST00000336803.1
CLDN2
claudin 2
chr20_+_44657845 0.072 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr2_+_234580525 0.072 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr6_+_33388013 0.072 ENST00000449372.2
SYNGAP1
synaptic Ras GTPase activating protein 1
chr19_-_40854417 0.070 ENST00000582006.1
ENST00000582783.1
C19orf47

chromosome 19 open reading frame 47

chr11_+_35684288 0.070 ENST00000299413.5
TRIM44
tripartite motif containing 44
chr10_-_123687497 0.070 ENST00000369040.3
ENST00000224652.6
ENST00000369043.3
ATE1


arginyltransferase 1


chr8_-_101734308 0.070 ENST00000519004.1
ENST00000519363.1
ENST00000520142.1
PABPC1


poly(A) binding protein, cytoplasmic 1


chr11_-_64512273 0.069 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RASGRP2


RAS guanyl releasing protein 2 (calcium and DAG-regulated)


chr11_-_123185475 0.069 ENST00000527774.1
ENST00000527533.1
RP11-109E10.1

RP11-109E10.1

chr1_+_197170592 0.069 ENST00000535699.1
CRB1
crumbs homolog 1 (Drosophila)
chr2_-_43823119 0.069 ENST00000403856.1
ENST00000404790.1
ENST00000405975.2
ENST00000415080.2
THADA



thyroid adenoma associated



chr15_-_51914810 0.069 ENST00000543779.2
ENST00000449909.3
DMXL2

Dmx-like 2

chr2_-_44223138 0.069 ENST00000260665.7
LRPPRC
leucine-rich pentatricopeptide repeat containing
chr1_+_226250379 0.069 ENST00000366815.3
ENST00000366814.3
H3F3A

H3 histone, family 3A

chr1_-_156390128 0.068 ENST00000368242.3
C1orf61
chromosome 1 open reading frame 61
chr17_-_65241281 0.068 ENST00000358691.5
ENST00000580168.1
HELZ

helicase with zinc finger

chr19_+_48673949 0.068 ENST00000328759.7
C19orf68
chromosome 19 open reading frame 68
chr11_+_64794875 0.067 ENST00000377244.3
ENST00000534637.1
ENST00000524831.1
SNX15


sorting nexin 15


chr2_+_234580499 0.067 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr17_+_46018872 0.067 ENST00000583599.1
ENST00000434554.2
ENST00000225573.4
ENST00000544840.1
ENST00000534893.1
PNPO




pyridoxamine 5'-phosphate oxidase




chr3_-_113415441 0.067 ENST00000491165.1
ENST00000316407.4
KIAA2018

KIAA2018

chr12_-_58240470 0.067 ENST00000548823.1
ENST00000398073.2
CTDSP2

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2

chr20_+_48429233 0.067 ENST00000417961.1
SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr6_-_100912785 0.066 ENST00000369208.3
SIM1
single-minded family bHLH transcription factor 1
chr11_-_118023490 0.066 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr8_+_22132810 0.066 ENST00000356766.6
PIWIL2
piwi-like RNA-mediated gene silencing 2
chr20_+_48429356 0.066 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
SLC9A8


solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8


chr12_-_45270151 0.064 ENST00000429094.2
NELL2
NEL-like 2 (chicken)
chr8_+_42396936 0.064 ENST00000416469.2
SMIM19
small integral membrane protein 19
chr11_-_64512469 0.064 ENST00000377485.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr2_-_32390801 0.064 ENST00000608489.1
RP11-563N4.1
RP11-563N4.1
chr1_-_6052463 0.064 ENST00000378156.4
NPHP4
nephronophthisis 4
chr1_+_235491714 0.063 ENST00000471812.1
ENST00000358966.2
ENST00000282841.5
ENST00000391855.2
GGPS1



geranylgeranyl diphosphate synthase 1



chr20_+_57466629 0.062 ENST00000371081.1
ENST00000338783.6
GNAS

GNAS complex locus

chr2_+_232573208 0.062 ENST00000409115.3
PTMA
prothymosin, alpha
chr12_+_56473910 0.062 ENST00000411731.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr2_-_60780607 0.061 ENST00000537768.1
ENST00000335712.6
ENST00000356842.4
BCL11A


B-cell CLL/lymphoma 11A (zinc finger protein)


chr6_+_42123141 0.061 ENST00000418175.1
ENST00000541991.1
ENST00000053469.4
ENST00000394237.1
ENST00000372963.1
GUCA1A



RP1-139D8.6
guanylate cyclase activator 1A (retina)



RP1-139D8.6
chr14_+_73525144 0.061 ENST00000261973.7
ENST00000540173.1
RBM25

RNA binding motif protein 25

chr1_+_43148059 0.060 ENST00000321358.7
ENST00000332220.6
YBX1

Y box binding protein 1

chr5_+_138609782 0.060 ENST00000361059.2
ENST00000514694.1
ENST00000504203.1
ENST00000502929.1
ENST00000394800.2
ENST00000509644.1
ENST00000505016.1
MATR3






matrin 3






chr18_+_56338750 0.060 ENST00000345724.3
MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr1_-_236030216 0.060 ENST00000389794.3
ENST00000389793.2
LYST

lysosomal trafficking regulator

chr9_+_96338647 0.060 ENST00000359246.4
PHF2
PHD finger protein 2
chr19_+_41036371 0.060 ENST00000392023.1
SPTBN4
spectrin, beta, non-erythrocytic 4
chr16_+_14280564 0.060 ENST00000572567.1
MKL2
MKL/myocardin-like 2
chr6_+_44238203 0.059 ENST00000451188.2
TMEM151B
transmembrane protein 151B
chr11_+_111957497 0.058 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
SDHD





succinate dehydrogenase complex, subunit D, integral membrane protein






Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.3 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.3 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.1 0.3 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.4 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.3 GO:0016598 protein arginylation(GO:0016598)
0.1 0.2 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.6 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.7 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.2 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 0.2 GO:1904199 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.1 0.2 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.2 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.2 GO:1901090 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.1 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0 0.2 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.1 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.0 0.1 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.1 GO:0060516 positive regulation of immature T cell proliferation in thymus(GO:0033092) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.9 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.3 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.1 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.1 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.2 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.0 GO:0060214 endocardium formation(GO:0060214)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.1 GO:1904978 regulation of endosome organization(GO:1904978)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.1 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.0 0.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.0 0.0 GO:0072069 DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
0.0 0.0 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.0 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.2 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.2 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.0 GO:0002086 diaphragm contraction(GO:0002086)
0.0 0.7 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0030091 protein repair(GO:0030091)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.1 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.0 0.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.0 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.3 GO:0034706 sodium channel complex(GO:0034706)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.4 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 0.3 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.6 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.3 GO:0004057 arginyltransferase activity(GO:0004057)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.2 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.7 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0097001 ceramide binding(GO:0097001)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.0 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.5 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.9 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo