Motif ID: NR4A3

Z-value: 0.786


Transcription factors associated with NR4A3:

Gene SymbolEntrez IDGene Name
NR4A3 ENSG00000119508.13 NR4A3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR4A3hg19_v2_chr9_+_102584128_1025841440.116.2e-01Click!


Activity profile for motif NR4A3.

activity profile for motif NR4A3


Sorted Z-values histogram for motif NR4A3

Sorted Z-values for motif NR4A3



Network of associatons between targets according to the STRING database.



First level regulatory network of NR4A3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_31518938 0.877 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chr8_+_99956759 0.846 ENST00000522510.1
ENST00000457907.2
OSR2

odd-skipped related transciption factor 2

chr9_-_130637244 0.828 ENST00000373156.1
AK1
adenylate kinase 1
chr14_+_22984601 0.795 ENST00000390509.1
TRAJ28
T cell receptor alpha joining 28
chr20_+_58179582 0.779 ENST00000371015.1
ENST00000395639.4
PHACTR3

phosphatase and actin regulator 3

chr7_+_13141097 0.776 ENST00000411542.1
AC011288.2
AC011288.2
chr2_-_31030277 0.742 ENST00000534090.2
ENST00000295055.8
CAPN13

calpain 13

chr1_+_150480576 0.707 ENST00000346569.6
ECM1
extracellular matrix protein 1
chr8_+_86376081 0.661 ENST00000285379.5
CA2
carbonic anhydrase II
chr4_-_681114 0.636 ENST00000503156.1
MFSD7
major facilitator superfamily domain containing 7
chr1_+_162351503 0.625 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr22_+_24891210 0.625 ENST00000382760.2
UPB1
ureidopropionase, beta
chr14_-_107283278 0.611 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr10_-_105845674 0.587 ENST00000353479.5
ENST00000369733.3
COL17A1

collagen, type XVII, alpha 1

chr16_+_2880296 0.578 ENST00000571723.1
ZG16B
zymogen granule protein 16B
chr8_+_99956662 0.572 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
OSR2


odd-skipped related transciption factor 2


chr19_-_1513188 0.567 ENST00000330475.4
ADAMTSL5
ADAMTS-like 5
chr7_-_45128472 0.560 ENST00000490531.2
NACAD
NAC alpha domain containing
chr1_+_200842083 0.552 ENST00000304244.2
GPR25
G protein-coupled receptor 25
chr6_+_19837592 0.550 ENST00000378700.3
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr12_-_123215306 0.513 ENST00000356987.2
ENST00000436083.2
HCAR1

hydroxycarboxylic acid receptor 1

chr11_-_66496430 0.511 ENST00000533211.1
SPTBN2
spectrin, beta, non-erythrocytic 2
chr11_+_66624527 0.505 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr22_-_24384240 0.500 ENST00000439996.2
ENST00000417870.1
GSTT1

glutathione S-transferase theta 1

chr4_+_41614720 0.496 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chrX_-_15619076 0.486 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chrX_+_44732757 0.483 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
KDM6A



lysine (K)-specific demethylase 6A



chr22_-_24384260 0.475 ENST00000248935.5
GSTT1
glutathione S-transferase theta 1
chr15_+_90728145 0.469 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
SEMA4B


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B


chr12_-_92536433 0.464 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79


chromosome 12 open reading frame 79


chr11_+_66059339 0.449 ENST00000327259.4
TMEM151A
transmembrane protein 151A
chr12_-_31158902 0.448 ENST00000544329.1
ENST00000418254.2
ENST00000222396.5
RP11-551L14.4


RP11-551L14.4


chr1_+_152957707 0.448 ENST00000368762.1
SPRR1A
small proline-rich protein 1A
chr7_-_95025661 0.440 ENST00000542556.1
ENST00000265627.5
ENST00000427422.1
ENST00000451904.1
PON1
PON3


paraoxonase 1
paraoxonase 3


chr20_+_61287711 0.434 ENST00000370507.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr16_+_29823552 0.433 ENST00000300797.6
PRRT2
proline-rich transmembrane protein 2
chrX_-_43741594 0.428 ENST00000536181.1
ENST00000378069.4
MAOB

monoamine oxidase B

chr5_-_66492562 0.427 ENST00000256447.4
CD180
CD180 molecule
chr5_-_42811986 0.427 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1


selenoprotein P, plasma, 1


chr9_-_35749162 0.424 ENST00000378094.4
ENST00000378103.3
GBA2

glucosidase, beta (bile acid) 2

chr5_+_218356 0.423 ENST00000264932.6
ENST00000504309.1
ENST00000510361.1
SDHA


succinate dehydrogenase complex, subunit A, flavoprotein (Fp)


chr4_-_48136217 0.421 ENST00000264316.4
TXK
TXK tyrosine kinase
chr16_+_29823427 0.410 ENST00000358758.7
ENST00000567659.1
ENST00000572820.1
PRRT2


proline-rich transmembrane protein 2


chr19_+_14138960 0.394 ENST00000431365.2
ENST00000585987.1
RLN3

relaxin 3

chr17_+_7211656 0.386 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr6_+_36973406 0.381 ENST00000274963.8
FGD2
FYVE, RhoGEF and PH domain containing 2
chr3_-_58652523 0.381 ENST00000489857.1
ENST00000358781.2
FAM3D

family with sequence similarity 3, member D

chr4_-_48014931 0.380 ENST00000420489.2
ENST00000504722.1
CNGA1

cyclic nucleotide gated channel alpha 1

chr19_-_49339080 0.377 ENST00000595764.1
HSD17B14
hydroxysteroid (17-beta) dehydrogenase 14
chr4_+_154622652 0.376 ENST00000260010.6
TLR2
toll-like receptor 2
chr14_-_81408063 0.376 ENST00000557411.1
CEP128
centrosomal protein 128kDa
chr1_-_47655686 0.375 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr9_+_124103625 0.372 ENST00000594963.1
AL161784.1
Uncharacterized protein
chr19_+_42301079 0.371 ENST00000596544.1
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr16_+_2880369 0.367 ENST00000572863.1
ZG16B
zymogen granule protein 16B
chr4_-_70080449 0.347 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr7_-_102158157 0.343 ENST00000541662.1
ENST00000306682.6
ENST00000465829.1
RASA4B


RAS p21 protein activator 4B


chr20_-_46415297 0.343 ENST00000467815.1
ENST00000359930.4
SULF2

sulfatase 2

chr14_-_21492251 0.342 ENST00000554398.1
NDRG2
NDRG family member 2
chr17_-_39928106 0.342 ENST00000540235.1
JUP
junction plakoglobin
chr4_-_74847800 0.341 ENST00000296029.3
PF4
platelet factor 4
chr20_-_46415341 0.340 ENST00000484875.1
ENST00000361612.4
SULF2

sulfatase 2

chr19_+_7011509 0.339 ENST00000377296.3
AC025278.1
Uncharacterized protein
chr1_-_144994909 0.333 ENST00000369347.4
ENST00000369354.3
PDE4DIP

phosphodiesterase 4D interacting protein

chr4_+_41614909 0.330 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1


LIM and calponin homology domains 1


chr22_+_30792980 0.330 ENST00000403484.1
ENST00000405717.3
ENST00000402592.3
SEC14L2


SEC14-like 2 (S. cerevisiae)


chr10_+_81272287 0.329 ENST00000520547.2
EIF5AL1
eukaryotic translation initiation factor 5A-like 1
chr20_-_23860373 0.327 ENST00000304710.4
CST5
cystatin D
chr20_+_1875942 0.327 ENST00000358771.4
SIRPA
signal-regulatory protein alpha
chr10_-_79397202 0.326 ENST00000372437.1
ENST00000372408.2
ENST00000372403.4
KCNMA1


potassium large conductance calcium-activated channel, subfamily M, alpha member 1


chr14_-_21492113 0.325 ENST00000554094.1
NDRG2
NDRG family member 2
chr10_-_8095412 0.321 ENST00000355358.1
ENST00000458727.1
GATA3-AS1
RP11-379F12.3
GATA3 antisense RNA 1
RP11-379F12.3
chr16_+_2880254 0.317 ENST00000570670.1
ZG16B
zymogen granule protein 16B
chr19_-_54876558 0.314 ENST00000391742.2
ENST00000434277.2
LAIR1

leukocyte-associated immunoglobulin-like receptor 1

chr15_-_52821020 0.313 ENST00000553916.1
MYO5A
myosin VA (heavy chain 12, myoxin)
chr19_-_4535233 0.313 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5


perilipin 5


chr8_-_145018905 0.311 ENST00000398774.2
PLEC
plectin
chr19_+_41117770 0.311 ENST00000601032.1
LTBP4
latent transforming growth factor beta binding protein 4
chr11_+_35198243 0.309 ENST00000528455.1
CD44
CD44 molecule (Indian blood group)
chr14_+_77648167 0.307 ENST00000554346.1
ENST00000298351.4
TMEM63C

transmembrane protein 63C

chr11_+_35198118 0.299 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44



CD44 molecule (Indian blood group)



chr1_-_17304771 0.298 ENST00000375534.3
MFAP2
microfibrillar-associated protein 2
chr12_-_7848364 0.293 ENST00000329913.3
GDF3
growth differentiation factor 3
chr20_+_30102231 0.292 ENST00000335574.5
ENST00000340852.5
ENST00000398174.3
ENST00000376127.3
ENST00000344042.5
HM13




histocompatibility (minor) 13




chr19_+_49713991 0.292 ENST00000597316.1
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr16_-_58328923 0.292 ENST00000567164.1
ENST00000219301.4
ENST00000569727.1
PRSS54


protease, serine, 54


chr20_-_48532019 0.292 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr16_+_2880157 0.291 ENST00000382280.3
ZG16B
zymogen granule protein 16B
chr19_+_39616410 0.289 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4






p21 protein (Cdc42/Rac)-activated kinase 4






chr18_-_31802282 0.288 ENST00000535475.1
NOL4
nucleolar protein 4
chr19_-_43702231 0.287 ENST00000597374.1
ENST00000599371.1
PSG4

pregnancy specific beta-1-glycoprotein 4

chr16_-_20709066 0.285 ENST00000520010.1
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr7_-_27169801 0.285 ENST00000511914.1
HOXA4
homeobox A4
chr14_-_106845789 0.284 ENST00000390617.2
IGHV3-35
immunoglobulin heavy variable 3-35 (non-functional)
chr5_-_42812143 0.284 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr17_-_79995553 0.284 ENST00000581584.1
ENST00000577712.1
ENST00000582900.1
ENST00000579155.1
ENST00000306869.2
DCXR




dicarbonyl/L-xylulose reductase




chr22_-_24110063 0.282 ENST00000520222.1
ENST00000401675.3
CHCHD10

coiled-coil-helix-coiled-coil-helix domain containing 10

chr17_-_39274606 0.282 ENST00000391413.2
KRTAP4-11
keratin associated protein 4-11
chr6_-_134861089 0.282 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr1_-_198990166 0.281 ENST00000427439.1
RP11-16L9.3
RP11-16L9.3
chr5_+_149569520 0.281 ENST00000230671.2
ENST00000524041.1
SLC6A7

solute carrier family 6 (neurotransmitter transporter), member 7

chr20_+_1246908 0.273 ENST00000381873.3
ENST00000381867.1
SNPH

syntaphilin

chr20_+_36946029 0.272 ENST00000417318.1
BPI
bactericidal/permeability-increasing protein
chr10_-_50970322 0.272 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr7_-_139763521 0.271 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr9_-_140095186 0.269 ENST00000409012.4
TPRN
taperin
chr19_-_7293942 0.269 ENST00000341500.5
ENST00000302850.5
INSR

insulin receptor

chr12_+_119616447 0.268 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr7_-_74489609 0.267 ENST00000329959.4
ENST00000503250.2
ENST00000543840.1
WBSCR16


Williams-Beuren syndrome chromosome region 16


chr11_-_117698765 0.267 ENST00000532119.1
FXYD2
FXYD domain containing ion transport regulator 2
chr11_-_117699413 0.266 ENST00000528014.1
FXYD2
FXYD domain containing ion transport regulator 2
chr10_-_50970382 0.265 ENST00000419399.1
ENST00000432695.1
OGDHL

oxoglutarate dehydrogenase-like

chr16_-_2827128 0.264 ENST00000494946.2
ENST00000409477.1
ENST00000572954.1
ENST00000262306.7
ENST00000409906.4
TCEB2




transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)




chr14_-_101295407 0.261 ENST00000596284.1
AL117190.2
AL117190.2
chr7_-_111202511 0.256 ENST00000452895.1
ENST00000452753.1
ENST00000331762.3
IMMP2L


IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)


chr1_+_92495528 0.253 ENST00000370383.4
EPHX4
epoxide hydrolase 4
chr3_-_58613323 0.252 ENST00000474531.1
ENST00000465970.1
FAM107A

family with sequence similarity 107, member A

chr16_-_58328870 0.251 ENST00000543437.1
PRSS54
protease, serine, 54
chr19_-_45826125 0.251 ENST00000221476.3
CKM
creatine kinase, muscle
chr7_+_100547156 0.249 ENST00000379458.4
MUC3A
Protein LOC100131514
chr20_-_30458491 0.245 ENST00000339738.5
DUSP15
dual specificity phosphatase 15
chr3_-_38691119 0.239 ENST00000333535.4
ENST00000413689.1
ENST00000443581.1
ENST00000425664.1
ENST00000451551.2
SCN5A




sodium channel, voltage-gated, type V, alpha subunit




chr19_+_11546440 0.239 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
PRKCSH





protein kinase C substrate 80K-H





chr15_-_78423567 0.236 ENST00000561190.1
ENST00000559645.1
ENST00000560618.1
ENST00000559054.1
CIB2



calcium and integrin binding family member 2



chr4_-_47983519 0.234 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1


cyclic nucleotide gated channel alpha 1


chr19_-_54876414 0.232 ENST00000474878.1
ENST00000348231.4
LAIR1

leukocyte-associated immunoglobulin-like receptor 1

chr10_-_100206642 0.231 ENST00000361490.4
ENST00000338546.5
ENST00000325103.6
HPS1


Hermansky-Pudlak syndrome 1


chr3_-_49314640 0.230 ENST00000436325.1
C3orf62
chromosome 3 open reading frame 62
chrX_+_117957741 0.230 ENST00000310164.2
ZCCHC12
zinc finger, CCHC domain containing 12
chr19_+_11546153 0.228 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH


protein kinase C substrate 80K-H


chr11_-_117698787 0.227 ENST00000260287.2
FXYD2
FXYD domain containing ion transport regulator 2
chr17_+_71161140 0.226 ENST00000357585.2
SSTR2
somatostatin receptor 2
chr1_-_205325850 0.226 ENST00000537168.1
KLHDC8A
kelch domain containing 8A
chr19_-_4540486 0.220 ENST00000306390.6
LRG1
leucine-rich alpha-2-glycoprotein 1
chr15_-_83621435 0.220 ENST00000450735.2
ENST00000426485.1
ENST00000399166.2
ENST00000304231.8
HOMER2



homer homolog 2 (Drosophila)



chr17_-_2996290 0.219 ENST00000331459.1
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr17_-_41132410 0.219 ENST00000409399.1
ENST00000421990.2
ENST00000409446.3
ENST00000453594.1
PTGES3L-AARSD1

PTGES3L

PTGES3L-AARSD1 readthrough

prostaglandin E synthase 3 (cytosolic)-like

chr11_+_67798114 0.218 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NDUFS8



NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)



chr11_-_110583912 0.218 ENST00000533353.1
ENST00000527598.1
ARHGAP20

Rho GTPase activating protein 20

chr18_+_55816546 0.217 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase


chr16_+_27413483 0.216 ENST00000337929.3
ENST00000564089.1
IL21R

interleukin 21 receptor

chr4_-_25032501 0.215 ENST00000382114.4
LGI2
leucine-rich repeat LGI family, member 2
chr22_+_50354104 0.213 ENST00000360612.4
PIM3
pim-3 oncogene
chr7_-_81399355 0.212 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr19_+_17416609 0.211 ENST00000602206.1
MRPL34
mitochondrial ribosomal protein L34
chr11_+_64073699 0.211 ENST00000405666.1
ENST00000468670.1
ESRRA

estrogen-related receptor alpha

chr7_-_142120321 0.209 ENST00000390377.1
TRBV7-7
T cell receptor beta variable 7-7
chr3_-_52860850 0.207 ENST00000441637.2
ITIH4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr11_+_10472223 0.204 ENST00000396554.3
ENST00000524866.1
AMPD3

adenosine monophosphate deaminase 3

chr7_-_20256965 0.203 ENST00000400331.5
ENST00000332878.4
MACC1

metastasis associated in colon cancer 1

chr4_-_4543700 0.202 ENST00000505286.1
ENST00000306200.2
STX18

syntaxin 18

chr10_-_28571015 0.201 ENST00000375719.3
ENST00000375732.1
MPP7

membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)

chr14_-_92198403 0.201 ENST00000553329.1
ENST00000256343.3
CATSPERB

catsper channel auxiliary subunit beta

chr19_+_42082506 0.200 ENST00000187608.9
ENST00000401445.2
CEACAM21

carcinoembryonic antigen-related cell adhesion molecule 21

chr11_+_67798363 0.200 ENST00000525628.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr20_+_31755934 0.199 ENST00000354932.5
BPIFA2
BPI fold containing family A, member 2
chr14_+_22309368 0.199 ENST00000390433.1
TRAV12-1
T cell receptor alpha variable 12-1
chr4_-_140527848 0.198 ENST00000608795.1
ENST00000608958.1
SETD7

SET domain containing (lysine methyltransferase) 7

chr4_+_154073469 0.197 ENST00000441616.1
TRIM2
tripartite motif containing 2
chr19_+_19639670 0.196 ENST00000436027.5
YJEFN3
YjeF N-terminal domain containing 3
chr7_-_6048650 0.194 ENST00000382321.4
ENST00000406569.3
PMS2

PMS2 postmeiotic segregation increased 2 (S. cerevisiae)

chr18_+_18822185 0.193 ENST00000424526.1
ENST00000400483.4
ENST00000431264.1
GREB1L


growth regulation by estrogen in breast cancer-like


chrX_+_65384182 0.191 ENST00000441993.2
ENST00000419594.1
HEPH

hephaestin

chr14_-_106622419 0.190 ENST00000390604.2
IGHV3-16
immunoglobulin heavy variable 3-16 (non-functional)
chr19_+_11546093 0.188 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr7_-_99774945 0.188 ENST00000292377.2
GPC2
glypican 2
chr11_+_60995849 0.188 ENST00000537932.1
PGA4
pepsinogen 4, group I (pepsinogen A)
chr2_+_37458776 0.184 ENST00000002125.4
ENST00000336237.6
ENST00000431821.1
NDUFAF7


NADH dehydrogenase (ubiquinone) complex I, assembly factor 7


chr19_+_45394477 0.184 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40




translocase of outer mitochondrial membrane 40 homolog (yeast)




chr20_-_35807970 0.183 ENST00000400440.2
ENST00000421643.1
MROH8

maestro heat-like repeat family member 8

chr8_-_110986918 0.183 ENST00000297404.1
KCNV1
potassium channel, subfamily V, member 1
chr18_+_18822216 0.182 ENST00000269218.6
GREB1L
growth regulation by estrogen in breast cancer-like
chr3_+_196439275 0.182 ENST00000296333.5
PIGX
phosphatidylinositol glycan anchor biosynthesis, class X
chr16_+_72090053 0.181 ENST00000576168.2
ENST00000567185.3
ENST00000567612.2
HP


haptoglobin


chr7_-_6048702 0.181 ENST00000265849.7
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr7_-_142176790 0.180 ENST00000390369.2
TRBV7-4
T cell receptor beta variable 7-4 (gene/pseudogene)
chr5_-_95158644 0.179 ENST00000237858.6
GLRX
glutaredoxin (thioltransferase)
chr13_-_52585547 0.179 ENST00000448424.2
ENST00000400370.3
ENST00000418097.2
ENST00000242839.4
ENST00000400366.3
ENST00000344297.5
ATP7B





ATPase, Cu++ transporting, beta polypeptide





chrX_+_65384052 0.179 ENST00000336279.5
ENST00000458621.1
HEPH

hephaestin

chr22_+_21128167 0.179 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr3_+_186435137 0.176 ENST00000447445.1
KNG1
kininogen 1
chr12_-_52761262 0.175 ENST00000257901.3
KRT85
keratin 85
chr4_-_1723040 0.175 ENST00000382936.3
ENST00000536901.1
ENST00000303277.2
TMEM129


transmembrane protein 129


chr17_-_72358001 0.175 ENST00000375366.3
BTBD17
BTB (POZ) domain containing 17
chr16_+_81272287 0.175 ENST00000425577.2
ENST00000564552.1
BCMO1

beta-carotene 15,15'-monooxygenase 1

chr11_-_130786333 0.175 ENST00000533214.1
ENST00000528555.1
ENST00000530356.1
ENST00000539184.1
SNX19



sorting nexin 19



chr1_+_24645807 0.174 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr4_-_159094194 0.174 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B


family with sequence similarity 198, member B


chr19_+_51273721 0.173 ENST00000270590.4
GPR32
G protein-coupled receptor 32
chr2_-_47403642 0.173 ENST00000456319.1
ENST00000409563.1
ENST00000272298.7
CALM2


calmodulin 2 (phosphorylase kinase, delta)


chr20_-_32308028 0.173 ENST00000409299.3
ENST00000217398.3
ENST00000344022.3
PXMP4


peroxisomal membrane protein 4, 24kDa


chr11_-_45939374 0.172 ENST00000533151.1
ENST00000241041.3
PEX16

peroxisomal biogenesis factor 16

chr1_+_25071848 0.172 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr16_+_11038403 0.171 ENST00000409552.3
CLEC16A
C-type lectin domain family 16, member A
chr3_-_139195350 0.171 ENST00000232217.2
RBP2
retinol binding protein 2, cellular
chr1_-_144994840 0.170 ENST00000369351.3
ENST00000369349.3
PDE4DIP

phosphodiesterase 4D interacting protein

chr14_-_102976135 0.168 ENST00000560748.1
ANKRD9
ankyrin repeat domain 9
chr18_+_55888767 0.167 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase


chr2_-_228497888 0.167 ENST00000264387.4
ENST00000409066.1
C2orf83

chromosome 2 open reading frame 83

chr10_-_79397391 0.166 ENST00000286628.8
ENST00000406533.3
ENST00000354353.5
ENST00000404857.1
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.2 0.7 GO:0042938 dipeptide transport(GO:0042938)
0.2 0.7 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 0.5 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.4 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.6 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.4 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) phenylpropanoid catabolic process(GO:0046271)
0.1 0.3 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.5 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.3 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.3 GO:0042732 D-xylose metabolic process(GO:0042732)
0.1 0.7 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.3 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.6 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.5 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047) membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.4 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 0.4 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.4 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.1 0.4 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.3 GO:0002159 desmosome assembly(GO:0002159) endothelial cell-cell adhesion(GO:0071603)
0.1 0.3 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 0.3 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 0.3 GO:1990535 transformation of host cell by virus(GO:0019087) neuron projection maintenance(GO:1990535)
0.1 0.4 GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) secretory granule localization(GO:0032252) endoplasmic reticulum localization(GO:0051643)
0.1 0.5 GO:0010044 response to aluminum ion(GO:0010044)
0.1 0.2 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.1 0.2 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1 0.2 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.3 GO:0042335 cuticle development(GO:0042335)
0.1 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.2 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.0 0.5 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.8 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.9 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.2 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:1902910 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.0 0.2 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.0 GO:0030817 regulation of cAMP biosynthetic process(GO:0030817)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.9 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.0 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.3 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.3 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.2 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.3 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 1.2 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.1 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.5 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.4 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.4 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.7 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 1.8 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.2 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.2 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 1.1 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.0 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.6 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.6 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.0 GO:0035623 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.0 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.2 GO:0015014 protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.0 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.6 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.0 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0044211 CTP salvage(GO:0044211)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.1 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.9 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.1 GO:0002034 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
0.1 0.5 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.3 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.6 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.4 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 1.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 1.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.4 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.9 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.4 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.5 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.5 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 0.5 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.4 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1 0.7 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.5 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.3 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.9 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 0.4 GO:0008422 glucosylceramidase activity(GO:0004348) beta-glucosidase activity(GO:0008422)
0.1 0.2 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.5 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.2 GO:0052856 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.1 0.4 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 0.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.4 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.1 0.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.3 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.2 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.6 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.2 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0042007 interleukin-18 binding(GO:0042007)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 1.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.0 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.0 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.0 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.8 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.9 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.0 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.3 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.8 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.7 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.7 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.1 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 0.9 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.3 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.3 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.1 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.8 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins