Motif ID: NR5A2

Z-value: 1.378


Transcription factors associated with NR5A2:

Gene SymbolEntrez IDGene Name
NR5A2 ENSG00000116833.9 NR5A2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR5A2hg19_v2_chr1_+_199996702_199996732-0.077.4e-01Click!


Activity profile for motif NR5A2.

activity profile for motif NR5A2


Sorted Z-values histogram for motif NR5A2

Sorted Z-values for motif NR5A2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR5A2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_58152524 3.399 ENST00000359926.3
PHACTR3
phosphatase and actin regulator 3
chr10_+_118187379 2.821 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chr20_+_58179582 2.262 ENST00000371015.1
ENST00000395639.4
PHACTR3

phosphatase and actin regulator 3

chr3_-_122102065 1.743 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
CCDC58


coiled-coil domain containing 58


chr11_+_66059339 1.623 ENST00000327259.4
TMEM151A
transmembrane protein 151A
chr2_+_135011731 1.493 ENST00000281923.2
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr4_-_74864386 1.459 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr1_+_152881014 1.416 ENST00000368764.3
ENST00000392667.2
IVL

involucrin

chr8_-_110704014 1.383 ENST00000529190.1
ENST00000422135.1
ENST00000419099.1
SYBU


syntabulin (syntaxin-interacting)


chr1_-_146696901 1.348 ENST00000369272.3
ENST00000441068.2
FMO5

flavin containing monooxygenase 5

chr5_-_134914673 1.347 ENST00000512158.1
CXCL14
chemokine (C-X-C motif) ligand 14
chr20_+_42086525 1.263 ENST00000244020.3
SRSF6
serine/arginine-rich splicing factor 6
chr5_-_54281407 1.222 ENST00000381403.4
ESM1
endothelial cell-specific molecule 1
chr9_-_130637244 1.219 ENST00000373156.1
AK1
adenylate kinase 1
chr22_+_31518938 1.211 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chr3_-_58652523 1.205 ENST00000489857.1
ENST00000358781.2
FAM3D

family with sequence similarity 3, member D

chr1_-_146697185 1.153 ENST00000533174.1
ENST00000254090.4
FMO5

flavin containing monooxygenase 5

chr6_-_97345689 1.103 ENST00000316149.7
NDUFAF4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
chr10_+_102891048 1.096 ENST00000467928.2
TLX1
T-cell leukemia homeobox 1
chr10_+_81107271 1.071 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chr14_-_21491477 1.051 ENST00000298684.5
ENST00000557169.1
ENST00000553563.1
NDRG2


NDRG family member 2


chr17_-_56084578 1.019 ENST00000582730.2
ENST00000584773.1
ENST00000585096.1
ENST00000258962.4
SRSF1



serine/arginine-rich splicing factor 1



chr7_-_95225768 1.000 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr21_+_41029235 0.988 ENST00000380618.1
B3GALT5
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
chr4_-_681114 0.988 ENST00000503156.1
MFSD7
major facilitator superfamily domain containing 7
chr8_+_144295067 0.904 ENST00000330824.2
GPIHBP1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr2_-_238499303 0.903 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr17_+_46970134 0.901 ENST00000503641.1
ENST00000514808.1
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr1_+_161195781 0.900 ENST00000367988.3
TOMM40L
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr14_-_21492251 0.892 ENST00000554398.1
NDRG2
NDRG family member 2
chr11_+_126139005 0.876 ENST00000263578.5
ENST00000442061.2
ENST00000532125.1
FOXRED1


FAD-dependent oxidoreductase domain containing 1


chr14_-_21492113 0.867 ENST00000554094.1
NDRG2
NDRG family member 2
chr17_+_46970178 0.862 ENST00000393366.2
ENST00000506855.1
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr22_-_24110063 0.858 ENST00000520222.1
ENST00000401675.3
CHCHD10

coiled-coil-helix-coiled-coil-helix domain containing 10

chr7_+_89841000 0.845 ENST00000287908.3
STEAP2
STEAP family member 2, metalloreductase
chr14_-_24806588 0.845 ENST00000554569.1
ENST00000555591.1
RIPK3
RP11-934B9.3
receptor-interacting serine-threonine kinase 3
Uncharacterized protein
chr19_+_15052301 0.844 ENST00000248072.3
OR7C2
olfactory receptor, family 7, subfamily C, member 2
chr1_-_149858227 0.842 ENST00000369155.2
HIST2H2BE
histone cluster 2, H2be
chr7_-_25164868 0.831 ENST00000409409.1
ENST00000409764.1
ENST00000413447.1
CYCS


cytochrome c, somatic


chr14_-_106054659 0.829 ENST00000390539.2
IGHA2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr19_-_4535233 0.821 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5


perilipin 5


chr17_+_46970127 0.815 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr7_+_89841024 0.815 ENST00000394626.1
STEAP2
STEAP family member 2, metalloreductase
chr9_-_130639997 0.792 ENST00000373176.1
AK1
adenylate kinase 1
chr3_+_186358148 0.761 ENST00000382134.3
ENST00000265029.3
FETUB

fetuin B

chr19_+_2249308 0.760 ENST00000592877.1
ENST00000221496.4
AMH

anti-Mullerian hormone

chr5_+_175085033 0.752 ENST00000377291.2
HRH2
histamine receptor H2
chr2_+_120189422 0.751 ENST00000306406.4
TMEM37
transmembrane protein 37
chr3_+_51705222 0.742 ENST00000457573.1
ENST00000341333.5
ENST00000412249.1
ENST00000425781.1
ENST00000415259.1
ENST00000395057.1
ENST00000416589.1
TEX264






testis expressed 264






chr5_+_218356 0.738 ENST00000264932.6
ENST00000504309.1
ENST00000510361.1
SDHA


succinate dehydrogenase complex, subunit A, flavoprotein (Fp)


chr19_+_17416609 0.737 ENST00000602206.1
MRPL34
mitochondrial ribosomal protein L34
chr3_+_186358200 0.727 ENST00000382136.3
FETUB
fetuin B
chr16_-_20709066 0.725 ENST00000520010.1
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr19_+_17416457 0.723 ENST00000252602.1
MRPL34
mitochondrial ribosomal protein L34
chr4_-_170947522 0.722 ENST00000361618.3
MFAP3L
microfibrillar-associated protein 3-like
chr11_-_34937858 0.712 ENST00000278359.5
APIP
APAF1 interacting protein
chr22_+_39348723 0.712 ENST00000402255.1
APOBEC3A
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
chr21_+_42694732 0.708 ENST00000398646.3
FAM3B
family with sequence similarity 3, member B
chr19_+_46850320 0.706 ENST00000391919.1
PPP5C
protein phosphatase 5, catalytic subunit
chr1_+_29138654 0.702 ENST00000234961.2
OPRD1
opioid receptor, delta 1
chr10_-_50970382 0.696 ENST00000419399.1
ENST00000432695.1
OGDHL

oxoglutarate dehydrogenase-like

chr1_-_207119738 0.696 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr1_-_203155868 0.696 ENST00000255409.3
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr10_-_50970322 0.695 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr1_+_228337553 0.691 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr3_+_133465228 0.682 ENST00000482271.1
ENST00000264998.3
TF

transferrin

chr19_+_46850251 0.671 ENST00000012443.4
PPP5C
protein phosphatase 5, catalytic subunit
chr17_+_900342 0.661 ENST00000327158.4
TIMM22
translocase of inner mitochondrial membrane 22 homolog (yeast)
chr8_-_110703819 0.648 ENST00000532779.1
ENST00000534578.1
SYBU

syntabulin (syntaxin-interacting)

chr17_-_9683238 0.639 ENST00000571771.1
DHRS7C
dehydrogenase/reductase (SDR family) member 7C
chr18_-_12377283 0.631 ENST00000269143.3
AFG3L2
AFG3-like AAA ATPase 2
chr11_+_57480046 0.626 ENST00000378312.4
ENST00000278422.4
TMX2

thioredoxin-related transmembrane protein 2

chr2_-_238499725 0.617 ENST00000264601.3
RAB17
RAB17, member RAS oncogene family
chr9_-_130679257 0.614 ENST00000361444.3
ENST00000335791.5
ENST00000343609.2
ST6GALNAC4


ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4


chr16_-_4588469 0.608 ENST00000588381.1
ENST00000563332.2
CDIP1

cell death-inducing p53 target 1

chr19_+_42212526 0.604 ENST00000221992.6
ENST00000405816.1
ENST00000598976.1
ENST00000435837.2
CEACAM5

CEA

carcinoembryonic antigen-related cell adhesion molecule 5

Uncharacterized protein

chr20_-_48532019 0.604 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr15_-_81616446 0.603 ENST00000302824.6
STARD5
StAR-related lipid transfer (START) domain containing 5
chr19_-_7293942 0.599 ENST00000341500.5
ENST00000302850.5
INSR

insulin receptor

chr11_+_66624527 0.596 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr2_-_238499131 0.596 ENST00000538644.1
RAB17
RAB17, member RAS oncogene family
chr6_+_107349392 0.594 ENST00000443043.1
ENST00000405204.2
ENST00000311381.5
C6orf203


chromosome 6 open reading frame 203


chr17_-_39928106 0.587 ENST00000540235.1
JUP
junction plakoglobin
chr4_-_69111401 0.585 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr2_-_31361543 0.580 ENST00000349752.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr2_-_7005785 0.575 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2


cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial


chr1_+_26146397 0.571 ENST00000374303.2
ENST00000533762.1
ENST00000529116.1
ENST00000474295.1
ENST00000488327.2
ENST00000472643.1
ENST00000526894.1
ENST00000524618.1
ENST00000374307.5
MTFR1L








mitochondrial fission regulator 1-like








chr13_+_47127322 0.569 ENST00000389798.3
LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr10_+_105156364 0.568 ENST00000369797.3
PDCD11
programmed cell death 11
chr22_-_42486747 0.566 ENST00000602404.1
NDUFA6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
chr16_-_58328870 0.553 ENST00000543437.1
PRSS54
protease, serine, 54
chr14_-_23624511 0.548 ENST00000529705.2
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr16_+_11038403 0.547 ENST00000409552.3
CLEC16A
C-type lectin domain family 16, member A
chr7_-_99569468 0.546 ENST00000419575.1
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr1_-_20126365 0.543 ENST00000294543.6
ENST00000375122.2
TMCO4

transmembrane and coiled-coil domains 4

chr16_-_58328923 0.542 ENST00000567164.1
ENST00000219301.4
ENST00000569727.1
PRSS54


protease, serine, 54


chr20_-_36889127 0.542 ENST00000279024.4
KIAA1755
KIAA1755
chr17_-_72855989 0.533 ENST00000293190.5
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr14_+_93897272 0.526 ENST00000393151.2
UNC79
unc-79 homolog (C. elegans)
chr17_+_7211656 0.520 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr1_+_26147319 0.514 ENST00000374300.3
MTFR1L
mitochondrial fission regulator 1-like
chr14_+_93897199 0.513 ENST00000553484.1
UNC79
unc-79 homolog (C. elegans)
chr16_-_12897642 0.512 ENST00000433677.2
ENST00000261660.4
ENST00000381774.4
CPPED1


calcineurin-like phosphoesterase domain containing 1


chr1_+_207226574 0.507 ENST00000367080.3
ENST00000367079.2
PFKFB2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

chr4_-_74904398 0.506 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chrX_+_153455547 0.505 ENST00000430054.1
OPN1MW
opsin 1 (cone pigments), medium-wave-sensitive
chr3_-_38691119 0.503 ENST00000333535.4
ENST00000413689.1
ENST00000443581.1
ENST00000425664.1
ENST00000451551.2
SCN5A




sodium channel, voltage-gated, type V, alpha subunit




chr19_+_55851221 0.502 ENST00000255613.3
ENST00000539076.1
SUV420H2
AC020922.1
suppressor of variegation 4-20 homolog 2 (Drosophila)
Uncharacterized protein
chr1_-_1711508 0.501 ENST00000378625.1
NADK
NAD kinase
chr5_+_140430979 0.496 ENST00000306549.3
PCDHB1
protocadherin beta 1
chr20_+_49126881 0.494 ENST00000371621.3
ENST00000541713.1
PTPN1

protein tyrosine phosphatase, non-receptor type 1

chr3_-_183735651 0.483 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ABCC5



ATP-binding cassette, sub-family C (CFTR/MRP), member 5



chr14_-_96180435 0.483 ENST00000556450.1
ENST00000555202.1
ENST00000554012.1
ENST00000402399.1
TCL1A



T-cell leukemia/lymphoma 1A



chr19_-_39826639 0.480 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG






glia maturation factor, gamma






chr3_-_195808952 0.478 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
TFRC



transferrin receptor



chr7_+_100318423 0.477 ENST00000252723.2
EPO
erythropoietin
chr11_+_77899920 0.475 ENST00000528910.1
ENST00000529308.1
USP35

ubiquitin specific peptidase 35

chr19_-_4517613 0.472 ENST00000301286.3
PLIN4
perilipin 4
chr3_+_9745510 0.472 ENST00000383831.3
CPNE9
copine family member IX
chr15_+_78441663 0.471 ENST00000299518.2
ENST00000558554.1
ENST00000557826.1
ENST00000561279.1
ENST00000559186.1
ENST00000560770.1
ENST00000559881.1
ENST00000559205.1
ENST00000441490.2
IDH3A








isocitrate dehydrogenase 3 (NAD+) alpha








chr22_+_23412479 0.471 ENST00000248996.4
GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr11_+_63304273 0.470 ENST00000439013.2
ENST00000255688.3
RARRES3

retinoic acid receptor responder (tazarotene induced) 3

chr9_+_33240157 0.468 ENST00000379721.3
SPINK4
serine peptidase inhibitor, Kazal type 4
chr14_-_106174960 0.467 ENST00000390547.2
IGHA1
immunoglobulin heavy constant alpha 1
chr7_-_25164969 0.465 ENST00000305786.2
CYCS
cytochrome c, somatic
chr1_-_40105617 0.461 ENST00000372852.3
HEYL
hes-related family bHLH transcription factor with YRPW motif-like
chr3_-_58613323 0.453 ENST00000474531.1
ENST00000465970.1
FAM107A

family with sequence similarity 107, member A

chr11_-_111781554 0.452 ENST00000526167.1
ENST00000528961.1
CRYAB

crystallin, alpha B

chr20_+_37434329 0.450 ENST00000299824.1
ENST00000373331.2
PPP1R16B

protein phosphatase 1, regulatory subunit 16B

chr5_-_131879205 0.449 ENST00000231454.1
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr8_+_67405755 0.447 ENST00000521495.1
C8orf46
chromosome 8 open reading frame 46
chr7_-_38389573 0.441 ENST00000390344.2
TRGV5
T cell receptor gamma variable 5
chr5_+_150639360 0.439 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr3_-_195808980 0.435 ENST00000360110.4
TFRC
transferrin receptor
chr17_+_48585794 0.432 ENST00000576179.1
ENST00000419930.1
MYCBPAP

MYCBP associated protein

chr5_-_148033726 0.431 ENST00000354217.2
ENST00000314512.6
ENST00000362016.2
HTR4


5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled


chr15_+_89346657 0.431 ENST00000439576.2
ACAN
aggrecan
chr17_-_3417062 0.429 ENST00000570318.1
ENST00000541913.1
SPATA22

spermatogenesis associated 22

chr6_+_43484760 0.424 ENST00000372389.3
ENST00000372344.2
ENST00000304004.3
ENST00000423780.1
POLR1C



polymerase (RNA) I polypeptide C, 30kDa



chr16_-_20681177 0.424 ENST00000524149.1
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr16_-_67224002 0.421 ENST00000563889.1
ENST00000564418.1
ENST00000545725.2
ENST00000314586.6
EXOC3L1



exocyst complex component 3-like 1



chr1_+_26146674 0.420 ENST00000525713.1
ENST00000374301.3
MTFR1L

mitochondrial fission regulator 1-like

chr17_+_40985407 0.419 ENST00000586114.1
ENST00000590720.1
ENST00000585805.1
ENST00000541124.1
ENST00000441946.2
ENST00000591152.1
ENST00000589469.1
ENST00000293362.3
ENST00000592169.1
PSME3








proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)








chr1_-_110284384 0.419 ENST00000540225.1
GSTM3
glutathione S-transferase mu 3 (brain)
chr19_+_19322758 0.418 ENST00000252575.6
NCAN
neurocan
chr19_-_40931891 0.416 ENST00000357949.4
SERTAD1
SERTA domain containing 1
chr6_-_52860171 0.413 ENST00000370963.4
GSTA4
glutathione S-transferase alpha 4
chr12_-_56652111 0.412 ENST00000267116.7
ANKRD52
ankyrin repeat domain 52
chr1_+_16348525 0.408 ENST00000331433.4
CLCNKA
chloride channel, voltage-sensitive Ka
chr15_-_77988485 0.408 ENST00000561030.1
LINGO1
leucine rich repeat and Ig domain containing 1
chr1_+_44584522 0.407 ENST00000372299.3
KLF17
Kruppel-like factor 17
chr4_-_74964904 0.402 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr6_+_32006159 0.401 ENST00000478281.1
ENST00000471671.1
ENST00000435122.2
CYP21A2


cytochrome P450, family 21, subfamily A, polypeptide 2


chr9_-_140095186 0.400 ENST00000409012.4
TPRN
taperin
chr20_+_1875942 0.397 ENST00000358771.4
SIRPA
signal-regulatory protein alpha
chr11_+_67798363 0.396 ENST00000525628.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr17_+_48423453 0.395 ENST00000017003.2
ENST00000509778.1
ENST00000507602.1
XYLT2


xylosyltransferase II


chr1_-_144995074 0.395 ENST00000534536.1
PDE4DIP
phosphodiesterase 4D interacting protein
chr6_+_32006042 0.393 ENST00000418967.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr1_-_27240455 0.391 ENST00000254227.3
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr4_+_74735102 0.387 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr17_+_79670386 0.387 ENST00000541223.1
ENST00000571730.1
ENST00000333676.3
SLC25A10
SLC25A10
MRPL12
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
Mitochondrial dicarboxylate carrier; Uncharacterized protein; cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier
mitochondrial ribosomal protein L12
chr4_-_170947485 0.383 ENST00000504999.1
MFAP3L
microfibrillar-associated protein 3-like
chr2_+_198365095 0.382 ENST00000409468.1
HSPE1
heat shock 10kDa protein 1
chr10_-_101190202 0.379 ENST00000543866.1
ENST00000370508.5
GOT1

glutamic-oxaloacetic transaminase 1, soluble

chr1_+_1447517 0.378 ENST00000378756.3
ENST00000378755.5
ATAD3A

ATPase family, AAA domain containing 3A

chr14_-_21490958 0.376 ENST00000554104.1
NDRG2
NDRG family member 2
chr15_+_45422131 0.375 ENST00000321429.4
DUOX1
dual oxidase 1
chr12_+_50505963 0.373 ENST00000550654.1
ENST00000548985.1
COX14

cytochrome c oxidase assembly homolog 14 (S. cerevisiae)

chr14_-_21491305 0.372 ENST00000554531.1
NDRG2
NDRG family member 2
chr6_+_31916733 0.372 ENST00000483004.1
CFB
complement factor B
chr8_+_145149930 0.371 ENST00000318911.4
CYC1
cytochrome c-1
chr3_-_14166316 0.371 ENST00000396914.3
ENST00000295767.5
CHCHD4

coiled-coil-helix-coiled-coil-helix domain containing 4

chr1_+_16348366 0.369 ENST00000375692.1
ENST00000420078.1
CLCNKA

chloride channel, voltage-sensitive Ka

chr4_+_41614720 0.368 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr3_-_187454281 0.368 ENST00000232014.4
BCL6
B-cell CLL/lymphoma 6
chr17_-_7991021 0.366 ENST00000319144.4
ALOX12B
arachidonate 12-lipoxygenase, 12R type
chr15_+_45422178 0.364 ENST00000389037.3
ENST00000558322.1
DUOX1

dual oxidase 1

chr11_-_34938039 0.364 ENST00000395787.3
APIP
APAF1 interacting protein
chr1_-_31661000 0.363 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
NKAIN1


Na+/K+ transporting ATPase interacting 1


chr4_-_170947565 0.363 ENST00000506764.1
MFAP3L
microfibrillar-associated protein 3-like
chr4_+_159593271 0.355 ENST00000512251.1
ENST00000511912.1
ETFDH

electron-transferring-flavoprotein dehydrogenase

chr11_-_110583912 0.354 ENST00000533353.1
ENST00000527598.1
ARHGAP20

Rho GTPase activating protein 20

chr20_+_13765596 0.352 ENST00000378106.5
ENST00000463598.1
NDUFAF5

NADH dehydrogenase (ubiquinone) complex I, assembly factor 5

chr15_-_91475706 0.351 ENST00000561036.1
HDDC3
HD domain containing 3
chr11_-_64512273 0.351 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RASGRP2


RAS guanyl releasing protein 2 (calcium and DAG-regulated)


chr8_+_125551338 0.350 ENST00000276689.3
ENST00000518008.1
ENST00000522532.1
ENST00000517367.1
NDUFB9



NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa



chr1_-_11907829 0.350 ENST00000376480.3
NPPA
natriuretic peptide A
chr7_+_44646162 0.350 ENST00000439616.2
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr12_+_50505762 0.350 ENST00000550487.1
ENST00000317943.2
COX14

cytochrome c oxidase assembly homolog 14 (S. cerevisiae)

chr2_-_74374995 0.349 ENST00000295326.4
BOLA3
bolA family member 3
chr1_-_156023580 0.346 ENST00000368309.3
UBQLN4
ubiquilin 4
chr4_-_170948361 0.345 ENST00000393702.3
MFAP3L
microfibrillar-associated protein 3-like
chr17_+_5185552 0.343 ENST00000262477.6
ENST00000408982.2
ENST00000575991.1
ENST00000537505.1
ENST00000546142.2
RABEP1




rabaptin, RAB GTPase binding effector protein 1




chr19_-_55574538 0.342 ENST00000415061.3
RDH13
retinol dehydrogenase 13 (all-trans/9-cis)
chr2_-_220119280 0.341 ENST00000392088.2
TUBA4A
tubulin, alpha 4a
chr12_-_53601055 0.341 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
ITGB7


integrin, beta 7


chr16_-_57481278 0.341 ENST00000567751.1
ENST00000568940.1
ENST00000563341.1
ENST00000565961.1
ENST00000569370.1
ENST00000567518.1
ENST00000565786.1
ENST00000394391.4
CIAPIN1







cytokine induced apoptosis inhibitor 1







chr22_-_39636914 0.339 ENST00000381551.4
PDGFB
platelet-derived growth factor beta polypeptide
chr12_-_53601000 0.338 ENST00000338737.4
ENST00000549086.2
ITGB7

integrin, beta 7


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.5 1.4 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.4 0.8 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.4 1.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.4 1.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.3 1.0 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.3 0.8 GO:0060545 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) positive regulation of necroptotic process(GO:0060545) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.2 1.7 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.2 1.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.2 1.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.2 3.6 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.2 1.7 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2 1.0 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.2 1.0 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.2 1.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2 1.9 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.2 0.6 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.2 0.6 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.2 0.7 GO:0006218 uridine catabolic process(GO:0006218)
0.2 0.9 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.2 0.7 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.2 0.7 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.2 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 0.5 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.2 2.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 0.8 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.2 0.5 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.2 0.8 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.2 0.5 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 0.4 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 1.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.5 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.3 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.1 1.0 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.1 0.7 GO:0042335 cuticle development(GO:0042335)
0.1 0.7 GO:0070383 DNA cytosine deamination(GO:0070383)
0.1 0.4 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.6 GO:0002159 desmosome assembly(GO:0002159) endothelial cell-cell adhesion(GO:0071603)
0.1 1.2 GO:0070269 pyroptosis(GO:0070269)
0.1 0.7 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 1.0 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 2.8 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.4 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 0.3 GO:0090149 synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
0.1 0.3 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 3.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.3 GO:0021571 rhombomere 5 development(GO:0021571)
0.1 0.3 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 0.4 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.3 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 0.5 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.3 GO:0009644 response to high light intensity(GO:0009644)
0.1 0.4 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.4 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.5 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.2 GO:1990927 short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.2 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.9 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.3 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1 0.2 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902229) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230) negative regulation of response to DNA damage stimulus(GO:2001021)
0.1 0.2 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.1 0.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.5 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.1 2.0 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.3 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 1.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.7 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.9 GO:0097286 iron ion import(GO:0097286)
0.1 0.5 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.1 0.3 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 0.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.2 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 0.5 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 0.2 GO:0072034 renal vesicle induction(GO:0072034)
0.1 1.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.3 GO:0060356 leucine import(GO:0060356)
0.1 0.4 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.1 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.2 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.8 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 4.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 1.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.4 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.3 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 1.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.6 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.7 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.6 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.1 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.0 0.2 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.3 GO:0070417 cellular response to cold(GO:0070417)
0.0 1.6 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.2 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.0 0.7 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.3 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.5 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.4 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.3 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.0 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.2 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.8 GO:0001696 gastric acid secretion(GO:0001696)
0.0 1.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.7 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.2 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628) somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 2.0 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.3 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.6 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.4 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.3 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 1.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.2 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.4 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.6 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 0.3 GO:1902037 negative regulation of erythrocyte differentiation(GO:0045647) negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.6 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 0.2 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.6 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.3 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.0 0.9 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.1 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.0 0.4 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.7 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.0 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 3.0 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.4 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.2 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 1.0 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.6 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 0.2 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.1 GO:0021938 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.1 GO:0061364 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834) response to cortisol(GO:0051414) apoptotic process involved in luteolysis(GO:0061364)
0.0 0.3 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.2 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.2 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 1.7 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.1 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.7 GO:0097503 sialylation(GO:0097503)
0.0 0.5 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.2 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.0 0.3 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:0045408 regulation of interleukin-6 biosynthetic process(GO:0045408)
0.0 0.6 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.2 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.1 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.6 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0009052 D-ribose metabolic process(GO:0006014) pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.2 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.2 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.0 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965) dorsal/ventral axon guidance(GO:0033563)
0.0 0.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.3 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.3 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.1 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 1.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.0 GO:1903762 positive regulation of actin filament-based movement(GO:1903116) positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.0 GO:0032824 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0 0.1 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.7 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 0.2 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.3 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.2 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.6 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.1 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.3 GO:0009081 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.0 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.0 0.2 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.0 GO:0035623 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.5 GO:0071806 protein transmembrane transport(GO:0071806)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.1 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.0 GO:0072720 response to dithiothreitol(GO:0072720)
0.0 0.0 GO:0015677 copper ion import(GO:0015677)
0.0 0.0 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.3 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.0 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.3 GO:0090218 positive regulation of lipid kinase activity(GO:0090218)
0.0 0.1 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.0 GO:1902822 cleavage furrow ingression(GO:0036090) regulation of late endosome to lysosome transport(GO:1902822) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.1 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.3 1.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 2.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 1.4 GO:1990635 proximal dendrite(GO:1990635)
0.2 0.7 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.2 2.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 2.0 GO:0097433 dense body(GO:0097433)
0.1 0.6 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.6 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.4 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.9 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.3 GO:0044753 amphisome(GO:0044753)
0.1 1.5 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.1 0.9 GO:0005915 zonula adherens(GO:0005915)
0.1 0.6 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.4 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.8 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.2 GO:0031523 Myb complex(GO:0031523)
0.1 0.3 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.7 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.3 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 0.3 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.1 0.6 GO:0097443 sorting endosome(GO:0097443)
0.1 0.9 GO:0097227 sperm annulus(GO:0097227)
0.0 0.2 GO:0070470 plasma membrane respiratory chain(GO:0070470)
0.0 1.5 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 3.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 3.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0032279 axonemal microtubule(GO:0005879) asymmetric synapse(GO:0032279)
0.0 1.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 1.4 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.8 GO:0036020 endolysosome membrane(GO:0036020)
0.0 1.4 GO:0070469 respiratory chain(GO:0070469)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 1.2 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.5 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.8 GO:0097342 ripoptosome(GO:0097342)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 4.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.6 GO:0001533 cornified envelope(GO:0001533)
0.0 2.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.2 GO:0005886 plasma membrane(GO:0005886)
0.0 0.9 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 4.7 GO:0030426 growth cone(GO:0030426)
0.0 0.7 GO:0042629 mast cell granule(GO:0042629)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.5 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.6 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 2.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 1.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.5 1.6 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.4 1.2 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.4 1.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.3 1.0 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.3 2.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 1.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 1.5 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.2 1.7 GO:0035473 lipase binding(GO:0035473)
0.2 1.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 1.7 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 2.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 1.0 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.2 0.5 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.2 5.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.4 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.7 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.6 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.7 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 2.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.1 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 1.7 GO:0015266 protein channel activity(GO:0015266)
0.1 0.4 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.4 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 1.3 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 0.4 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.5 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.5 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.3 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.3 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.1 2.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.3 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.1 0.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.3 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 0.3 GO:0042007 interleukin-18 binding(GO:0042007)
0.1 0.7 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.4 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 0.5 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 0.8 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.3 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.7 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.7 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 0.8 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 1.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.6 GO:0043559 insulin binding(GO:0043559) PTB domain binding(GO:0051425)
0.1 0.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.3 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.2 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 1.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.8 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.6 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.3 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.1 1.9 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.6 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.2 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.3 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.4 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.3 GO:0003872 6-phosphofructokinase activity(GO:0003872) phosphofructokinase activity(GO:0008443)
0.1 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.0 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.2 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 0.7 GO:0004568 chitinase activity(GO:0004568)
0.0 0.8 GO:0032052 bile acid binding(GO:0032052)
0.0 1.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.6 GO:0004985 opioid receptor activity(GO:0004985)
0.0 1.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 1.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 2.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 2.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 1.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.3 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.7 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.4 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.0 GO:0004917 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.9 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0030369 ICAM-3 receptor activity(GO:0030369) virion binding(GO:0046790)
0.0 0.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.4 GO:0008009 chemokine activity(GO:0008009)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.0 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 2.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 2.4 GO:0005125 cytokine activity(GO:0005125)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID_ALK2_PATHWAY ALK2 signaling events
0.0 1.1 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.2 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 2.0 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 0.7 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.5 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 1.5 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.4 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 1.3 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 0.8 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 1.5 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.7 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.4 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.8 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 2.9 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 2.2 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 2.2 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.3 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.2 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.1 PID_IL3_PATHWAY IL3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.6 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.1 3.1 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 2.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.1 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.4 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 5.1 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 1.5 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.5 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.8 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.7 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME_OPSINS Genes involved in Opsins
0.0 0.7 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.9 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 2.4 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.7 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 1.2 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 1.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.8 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.4 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.4 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.5 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 0.8 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.8 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.5 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.6 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.6 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.7 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.3 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.5 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.9 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.7 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.8 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.4 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.6 REACTOME_PLC_BETA_MEDIATED_EVENTS Genes involved in PLC beta mediated events
0.0 0.6 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.2 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.3 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.7 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.6 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.8 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.7 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins