Motif ID: PBX1

Z-value: 0.748


Transcription factors associated with PBX1:

Gene SymbolEntrez IDGene Name
PBX1 ENSG00000185630.14 PBX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PBX1hg19_v2_chr1_+_164528866_1645288770.743.5e-05Click!


Activity profile for motif PBX1.

activity profile for motif PBX1


Sorted Z-values histogram for motif PBX1

Sorted Z-values for motif PBX1



Network of associatons between targets according to the STRING database.



First level regulatory network of PBX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_63638339 3.169 ENST00000343837.3
ENST00000469440.1
SNTN

sentan, cilia apical structure protein

chr1_+_104293028 2.031 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr18_+_44526786 2.008 ENST00000245121.5
ENST00000356157.7
KATNAL2

katanin p60 subunit A-like 2

chr1_+_104159999 1.934 ENST00000414303.2
ENST00000423678.1
AMY2A

amylase, alpha 2A (pancreatic)

chr9_+_140135665 1.774 ENST00000340384.4
TUBB4B
tubulin, beta 4B class IVb
chr4_-_147867025 1.576 ENST00000502319.1
ENST00000325106.4
ENST00000504425.1
TTC29


tetratricopeptide repeat domain 29


chr4_-_147866960 1.521 ENST00000513335.1
TTC29
tetratricopeptide repeat domain 29
chr4_+_69962185 1.473 ENST00000305231.7
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr10_+_51549498 1.465 ENST00000358559.2
ENST00000298239.6
MSMB

microseminoprotein, beta-

chr4_+_69962212 1.442 ENST00000508661.1
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr2_-_154335300 1.327 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chrX_+_125953746 1.260 ENST00000371125.3
CXorf64
chromosome X open reading frame 64
chr20_+_52105495 1.234 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr4_+_69681710 1.190 ENST00000265403.7
ENST00000458688.2
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr11_+_71903169 1.122 ENST00000393676.3
FOLR1
folate receptor 1 (adult)
chr8_+_99076750 1.107 ENST00000545282.1
C8orf47
chromosome 8 open reading frame 47
chr11_-_34937858 1.002 ENST00000278359.5
APIP
APAF1 interacting protein
chr8_+_99076509 0.967 ENST00000318528.3
C8orf47
chromosome 8 open reading frame 47
chr5_+_140213815 0.955 ENST00000525929.1
ENST00000378125.3
PCDHA7

protocadherin alpha 7

chr5_-_42825983 0.943 ENST00000506577.1
SEPP1
selenoprotein P, plasma, 1
chr4_+_77356248 0.917 ENST00000296043.6
SHROOM3
shroom family member 3
chr22_-_39190116 0.903 ENST00000406622.1
ENST00000216068.4
ENST00000406199.3
SUN2
DNAL4

Sad1 and UNC84 domain containing 2
dynein, axonemal, light chain 4

chr10_+_63422695 0.855 ENST00000330194.2
ENST00000389639.3
C10orf107

chromosome 10 open reading frame 107

chr3_+_129158926 0.848 ENST00000347300.2
ENST00000296266.3
IFT122

intraflagellar transport 122 homolog (Chlamydomonas)

chr3_+_129159039 0.812 ENST00000507564.1
ENST00000431818.2
ENST00000504021.1
ENST00000349441.2
ENST00000348417.2
ENST00000440957.2
IFT122





intraflagellar transport 122 homolog (Chlamydomonas)





chr7_-_120498357 0.797 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12


tetraspanin 12


chr22_+_29138013 0.784 ENST00000216027.3
ENST00000398941.2
HSCB

HscB mitochondrial iron-sulfur cluster co-chaperone

chr13_+_97928395 0.729 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr12_+_20968608 0.705 ENST00000553473.1
ENST00000554957.1
ENST00000381541.3
ENST00000540229.1
SLCO1B3
SLCO1B7
LST3

solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein

chr11_-_34938039 0.645 ENST00000395787.3
APIP
APAF1 interacting protein
chr12_+_21168630 0.643 ENST00000421593.2
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr3_-_112564797 0.625 ENST00000398214.1
ENST00000448932.1
CD200R1L

CD200 receptor 1-like

chr4_-_105416039 0.598 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr7_+_23637763 0.586 ENST00000410069.1
CCDC126
coiled-coil domain containing 126
chr16_+_16484691 0.578 ENST00000344087.4
NPIPA7
nuclear pore complex interacting protein family, member A7
chr6_+_27114861 0.576 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr2_-_27886676 0.557 ENST00000337768.5
SUPT7L
suppressor of Ty 7 (S. cerevisiae)-like
chr2_+_12857015 0.543 ENST00000155926.4
TRIB2
tribbles pseudokinase 2
chr11_-_114466477 0.543 ENST00000375478.3
NXPE4
neurexophilin and PC-esterase domain family, member 4
chr19_+_44645700 0.542 ENST00000592437.1
ZNF234
zinc finger protein 234
chr1_+_226250379 0.538 ENST00000366815.3
ENST00000366814.3
H3F3A

H3 histone, family 3A

chr15_-_37393406 0.520 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2


Meis homeobox 2


chr1_-_152131703 0.512 ENST00000316073.3
RPTN
repetin
chr14_+_88851874 0.512 ENST00000393545.4
ENST00000356583.5
ENST00000555401.1
ENST00000553885.1
SPATA7



spermatogenesis associated 7



chr17_+_21030260 0.498 ENST00000579303.1
DHRS7B
dehydrogenase/reductase (SDR family) member 7B
chr2_+_12857043 0.495 ENST00000381465.2
TRIB2
tribbles pseudokinase 2
chr17_+_58755184 0.493 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3


breast carcinoma amplified sequence 3


chr5_+_43603229 0.491 ENST00000344920.4
ENST00000512996.2
NNT

nicotinamide nucleotide transhydrogenase

chr3_-_161090660 0.477 ENST00000359175.4
SPTSSB
serine palmitoyltransferase, small subunit B
chr3_+_148508845 0.477 ENST00000491148.1
CPB1
carboxypeptidase B1 (tissue)
chr8_-_108510224 0.463 ENST00000517746.1
ENST00000297450.3
ANGPT1

angiopoietin 1

chr17_+_1665345 0.456 ENST00000576406.1
ENST00000571149.1
SERPINF1

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

chr4_-_70080449 0.456 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr17_+_43239231 0.451 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
HEXIM2


hexamethylene bis-acetamide inducible 2


chr3_-_112693759 0.430 ENST00000440122.2
ENST00000490004.1
CD200R1

CD200 receptor 1

chr5_+_43602750 0.418 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT


nicotinamide nucleotide transhydrogenase


chr19_+_58341656 0.407 ENST00000442832.4
ENST00000594901.1
ZNF587B

zinc finger protein 587B

chr19_+_11485333 0.402 ENST00000312423.2
SWSAP1
SWIM-type zinc finger 7 associated protein 1
chr12_+_56401268 0.401 ENST00000262032.5
IKZF4
IKAROS family zinc finger 4 (Eos)
chr19_-_58400148 0.394 ENST00000595048.1
ENST00000600634.1
ENST00000595295.1
ENST00000596604.1
ENST00000597342.1
ENST00000597807.1
ZNF814





zinc finger protein 814





chr14_+_24583836 0.393 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DCAF11








DDB1 and CUL4 associated factor 11








chr15_-_44069741 0.385 ENST00000319359.3
ELL3
elongation factor RNA polymerase II-like 3
chr16_+_19222479 0.383 ENST00000568433.1
SYT17
synaptotagmin XVII
chr12_+_81471816 0.377 ENST00000261206.3
ACSS3
acyl-CoA synthetase short-chain family member 3
chr12_-_15104040 0.374 ENST00000541644.1
ENST00000545895.1
ARHGDIB

Rho GDP dissociation inhibitor (GDI) beta

chr3_-_149510553 0.366 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ANKUB1


ankyrin repeat and ubiquitin domain containing 1


chr6_-_27775694 0.333 ENST00000377401.2
HIST1H2BL
histone cluster 1, H2bl
chr17_+_46125707 0.333 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
NFE2L1



nuclear factor, erythroid 2-like 1



chr11_+_61717336 0.331 ENST00000378042.3
BEST1
bestrophin 1
chr3_-_11645925 0.329 ENST00000413604.1
VGLL4
vestigial like 4 (Drosophila)
chr17_+_43239191 0.326 ENST00000589230.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr6_-_167040731 0.325 ENST00000265678.4
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr12_+_133657461 0.316 ENST00000412146.2
ENST00000544426.1
ENST00000440984.2
ENST00000319849.3
ENST00000440550.2
ZNF140




zinc finger protein 140




chr4_-_168155169 0.312 ENST00000534949.1
ENST00000535728.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr11_+_61717279 0.301 ENST00000378043.4
BEST1
bestrophin 1
chr5_-_132073111 0.297 ENST00000403231.1
KIF3A
kinesin family member 3A
chr17_-_39296739 0.290 ENST00000345847.4
KRTAP4-6
keratin associated protein 4-6
chr5_+_140207536 0.285 ENST00000529310.1
ENST00000527624.1
PCDHA6

protocadherin alpha 6

chr7_+_77325738 0.281 ENST00000334955.8
RSBN1L
round spermatid basic protein 1-like
chr11_-_126870655 0.275 ENST00000525144.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr22_-_30866564 0.271 ENST00000435069.1
ENST00000415957.2
ENST00000540910.1
SEC14L3


SEC14-like 3 (S. cerevisiae)


chr7_-_112430647 0.267 ENST00000312814.6
TMEM168
transmembrane protein 168
chr1_-_28241226 0.264 ENST00000373912.3
ENST00000373909.3
RPA2

replication protein A2, 32kDa

chrX_+_56590002 0.259 ENST00000338222.5
UBQLN2
ubiquilin 2
chr7_-_112430427 0.258 ENST00000449743.1
ENST00000441474.1
ENST00000454074.1
ENST00000447395.1
TMEM168



transmembrane protein 168



chr17_+_45973516 0.257 ENST00000376741.4
SP2
Sp2 transcription factor
chr5_-_10761206 0.256 ENST00000432074.2
ENST00000230895.6
DAP

death-associated protein

chr14_-_74551096 0.252 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr1_-_54405773 0.252 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chrX_-_70473957 0.249 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
ZMYM3


zinc finger, MYM-type 3


chr11_+_68228186 0.247 ENST00000393799.2
ENST00000393800.2
ENST00000528635.1
ENST00000533127.1
ENST00000529907.1
ENST00000529344.1
ENST00000534534.1
ENST00000524845.1
ENST00000265637.4
ENST00000524904.1
ENST00000393801.3
ENST00000265636.5
ENST00000529710.1
PPP6R3












protein phosphatase 6, regulatory subunit 3












chr6_+_26124373 0.244 ENST00000377791.2
ENST00000602637.1
HIST1H2AC

histone cluster 1, H2ac

chr12_-_39734783 0.242 ENST00000552961.1
KIF21A
kinesin family member 21A
chr5_+_159656437 0.242 ENST00000402432.3
FABP6
fatty acid binding protein 6, ileal
chr14_+_50234309 0.242 ENST00000298307.5
KLHDC2
kelch domain containing 2
chr14_+_23938891 0.241 ENST00000408901.3
ENST00000397154.3
ENST00000555128.1
NGDN


neuroguidin, EIF4E binding protein


chr11_+_122753391 0.238 ENST00000307257.6
ENST00000227349.2
C11orf63

chromosome 11 open reading frame 63

chrM_+_4431 0.236 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr3_+_179280668 0.232 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
ACTL6A



actin-like 6A



chr19_+_46498704 0.232 ENST00000595358.1
ENST00000594672.1
ENST00000536603.1
CCDC61


coiled-coil domain containing 61


chr11_-_31531121 0.231 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L






IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)






chr19_+_41770269 0.225 ENST00000378215.4
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr16_+_19079215 0.224 ENST00000544894.2
ENST00000561858.1
COQ7

coenzyme Q7 homolog, ubiquinone (yeast)

chr2_-_88427568 0.224 ENST00000393750.3
ENST00000295834.3
FABP1

fatty acid binding protein 1, liver

chr14_-_74551172 0.223 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr6_-_15586238 0.221 ENST00000462989.2
DTNBP1
dystrobrevin binding protein 1
chr11_-_40315640 0.216 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr1_-_28241024 0.213 ENST00000313433.7
ENST00000444045.1
RPA2

replication protein A2, 32kDa

chrX_-_6453159 0.213 ENST00000381089.3
ENST00000398729.1
VCX3A

variable charge, X-linked 3A

chr8_+_98788003 0.212 ENST00000521545.2
LAPTM4B
lysosomal protein transmembrane 4 beta
chr19_+_41770236 0.209 ENST00000392006.3
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chrX_-_70474499 0.209 ENST00000353904.2
ZMYM3
zinc finger, MYM-type 3
chr19_+_19030497 0.206 ENST00000438170.2
DDX49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr7_+_75024903 0.204 ENST00000323819.3
ENST00000430211.1
TRIM73

tripartite motif containing 73

chr16_+_15596123 0.203 ENST00000452191.2
C16orf45
chromosome 16 open reading frame 45
chr4_-_140005443 0.202 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
ELF2


E74-like factor 2 (ets domain transcription factor)


chr15_+_44069276 0.202 ENST00000381359.1
SERF2
small EDRK-rich factor 2
chr16_+_19078960 0.201 ENST00000568985.1
ENST00000566110.1
COQ7

coenzyme Q7 homolog, ubiquinone (yeast)

chrX_+_1734051 0.200 ENST00000381229.4
ENST00000381233.3
ASMT

acetylserotonin O-methyltransferase

chr19_+_19030478 0.198 ENST00000247003.4
DDX49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr13_-_46679185 0.195 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr16_-_29499154 0.193 ENST00000354563.5
RP11-231C14.4
Uncharacterized protein
chr9_-_14308004 0.191 ENST00000493697.1
NFIB
nuclear factor I/B
chr5_+_98109322 0.188 ENST00000513185.1
RGMB
repulsive guidance molecule family member b
chr5_-_177210399 0.187 ENST00000510276.1
FAM153A
family with sequence similarity 153, member A
chr10_-_18948156 0.185 ENST00000414939.1
ENST00000449529.1
ENST00000456217.1
ENST00000444660.1
ARL5B-AS1



ARL5B antisense RNA 1



chr2_-_96971232 0.179 ENST00000323853.5
SNRNP200
small nuclear ribonucleoprotein 200kDa (U5)
chr8_+_98788057 0.177 ENST00000517924.1
LAPTM4B
lysosomal protein transmembrane 4 beta
chr13_-_46679144 0.176 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr3_-_120461378 0.176 ENST00000273375.3
RABL3
RAB, member of RAS oncogene family-like 3
chr2_-_158182410 0.175 ENST00000419116.2
ENST00000410096.1
ERMN

ermin, ERM-like protein

chr12_-_122985067 0.172 ENST00000540586.1
ENST00000543897.1
ZCCHC8

zinc finger, CCHC domain containing 8

chr4_+_187148556 0.169 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1



kallikrein B, plasma (Fletcher factor) 1



chr7_-_77325545 0.168 ENST00000447009.1
ENST00000416650.1
ENST00000440088.1
ENST00000430801.1
ENST00000398043.2
RSBN1L-AS1




RSBN1L antisense RNA 1




chr1_+_179262905 0.163 ENST00000539888.1
ENST00000540564.1
ENST00000535686.1
ENST00000367619.3
SOAT1



sterol O-acyltransferase 1



chr17_-_26694979 0.163 ENST00000438614.1
VTN
vitronectin
chr12_-_56848426 0.162 ENST00000257979.4
MIP
major intrinsic protein of lens fiber
chr16_-_30546141 0.160 ENST00000535210.1
ENST00000395094.3
ZNF747

zinc finger protein 747

chr13_+_115079949 0.156 ENST00000361283.1
CHAMP1
chromosome alignment maintaining phosphoprotein 1
chr16_-_49890016 0.152 ENST00000563137.2
ZNF423
zinc finger protein 423
chr18_-_59854203 0.151 ENST00000589339.1
ENST00000357637.5
ENST00000585458.1
ENST00000400334.3
ENST00000587134.1
ENST00000585923.1
ENST00000590765.1
ENST00000589720.1
ENST00000588571.1
ENST00000585344.1
PIGN









phosphatidylinositol glycan anchor biosynthesis, class N









chr19_+_35417939 0.150 ENST00000601142.1
ENST00000426813.2
ZNF30

zinc finger protein 30

chr3_-_143567262 0.148 ENST00000474151.1
ENST00000316549.6
SLC9A9

solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9

chrM_+_9207 0.148 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr17_-_26695013 0.147 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr10_+_60028818 0.144 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr17_+_7758374 0.144 ENST00000301599.6
ENST00000574668.1
TMEM88

transmembrane protein 88

chrX_+_53123314 0.141 ENST00000605526.1
ENST00000604062.1
ENST00000604369.1
ENST00000366185.2
ENST00000604849.1
RP11-258C19.5




long intergenic non-protein coding RNA 1155




chrX_-_70474377 0.141 ENST00000373978.1
ENST00000373981.1
ZMYM3

zinc finger, MYM-type 3

chr18_+_29598335 0.139 ENST00000217740.3
RNF125
ring finger protein 125, E3 ubiquitin protein ligase
chr3_-_12587055 0.138 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr14_-_69619823 0.136 ENST00000341516.5
DCAF5
DDB1 and CUL4 associated factor 5
chr2_+_79412357 0.135 ENST00000466387.1
CTNNA2
catenin (cadherin-associated protein), alpha 2
chrX_+_7810303 0.133 ENST00000381059.3
ENST00000341408.4
VCX

variable charge, X-linked

chr17_+_73663402 0.128 ENST00000355423.3
SAP30BP
SAP30 binding protein
chr5_-_94417339 0.126 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1


multiple C2 domains, transmembrane 1


chr16_-_20364030 0.125 ENST00000396134.2
ENST00000573567.1
ENST00000570757.1
ENST00000424589.1
ENST00000302509.4
ENST00000571174.1
ENST00000576688.1
UMOD






uromodulin






chr6_+_83777374 0.121 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
DOPEY1


dopey family member 1


chr10_+_124320156 0.120 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
DMBT1





deleted in malignant brain tumors 1





chr3_+_155860751 0.117 ENST00000471742.1
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr6_-_31560729 0.115 ENST00000340027.5
ENST00000376073.4
ENST00000376072.3
NCR3


natural cytotoxicity triggering receptor 3


chr6_-_31782813 0.111 ENST00000375654.4
HSPA1L
heat shock 70kDa protein 1-like
chr1_-_1690014 0.110 ENST00000400922.2
ENST00000342348.5
NADK

NAD kinase

chr6_-_26199499 0.109 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr5_-_132073210 0.108 ENST00000378735.1
ENST00000378746.4
KIF3A

kinesin family member 3A

chr6_-_51952367 0.107 ENST00000340994.4
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr2_-_109605663 0.107 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR


ectodysplasin A receptor


chr2_+_181845298 0.104 ENST00000410062.4
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr15_+_69222827 0.104 ENST00000448182.3
ENST00000260364.5
ENST00000310673.3
NOX5

SPESP1
NADPH oxidase, EF-hand calcium binding domain 5

sperm equatorial segment protein 1
chr5_-_86708833 0.098 ENST00000256897.4
CCNH
cyclin H
chr6_-_7313381 0.098 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
SSR1






signal sequence receptor, alpha






chr1_-_146068184 0.097 ENST00000604894.1
ENST00000369323.3
ENST00000479926.2
NBPF11


neuroblastoma breakpoint family, member 11


chr13_-_24895566 0.097 ENST00000422229.2
AL359736.1
protein PCOTH isoform 1
chr8_-_10512569 0.097 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr16_-_20364122 0.097 ENST00000396138.4
ENST00000577168.1
UMOD

uromodulin

chrX_-_110655306 0.096 ENST00000371993.2
DCX
doublecortin
chr22_+_35695793 0.095 ENST00000456128.1
ENST00000449058.2
ENST00000411850.1
ENST00000425375.1
ENST00000436462.2
ENST00000382034.5
TOM1





target of myb1 (chicken)





chr8_-_116681221 0.095 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr17_+_72983674 0.094 ENST00000337231.5
CDR2L
cerebellar degeneration-related protein 2-like
chr5_-_86708670 0.094 ENST00000504878.1
CCNH
cyclin H
chr12_-_102455846 0.093 ENST00000545679.1
CCDC53
coiled-coil domain containing 53
chr15_+_34638066 0.092 ENST00000333756.4
NUTM1
NUT midline carcinoma, family member 1
chr3_+_193853927 0.091 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr12_-_102455902 0.091 ENST00000240079.6
CCDC53
coiled-coil domain containing 53
chr1_-_115323245 0.091 ENST00000060969.5
ENST00000369528.5
SIKE1

suppressor of IKBKE 1

chrM_+_10053 0.091 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr11_+_22689648 0.089 ENST00000278187.3
GAS2
growth arrest-specific 2
chr1_-_3713042 0.088 ENST00000378251.1
LRRC47
leucine rich repeat containing 47
chrX_+_95939638 0.087 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
DIAPH2


diaphanous-related formin 2


chr14_+_22985251 0.085 ENST00000390510.1
TRAJ27
T cell receptor alpha joining 27
chr9_-_6015607 0.084 ENST00000259569.5
RANBP6
RAN binding protein 6
chr7_+_134331550 0.084 ENST00000344924.3
ENST00000418040.1
ENST00000393132.2
BPGM


2,3-bisphosphoglycerate mutase


chr5_+_68513622 0.081 ENST00000512880.1
ENST00000602380.1
MRPS36

mitochondrial ribosomal protein S36

chr4_+_120056939 0.079 ENST00000307128.5
MYOZ2
myozenin 2
chr18_-_48346298 0.079 ENST00000398439.3
MRO
maestro
chr3_-_150264272 0.076 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1


stress-associated endoplasmic reticulum protein 1


chr2_-_27886460 0.073 ENST00000404798.2
ENST00000405491.1
ENST00000464789.2
ENST00000406540.1
SUPT7L



suppressor of Ty 7 (S. cerevisiae)-like



chr19_+_58180303 0.073 ENST00000318203.5
ZSCAN4
zinc finger and SCAN domain containing 4
chr1_-_147610081 0.072 ENST00000369226.3
NBPF24
neuroblastoma breakpoint family, member 24
chr12_+_101988627 0.070 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1








myosin binding protein C, slow type









Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0060830 intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.4 1.1 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.3 1.9 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 1.0 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2 0.9 GO:0006740 NADPH regeneration(GO:0006740)
0.2 0.5 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.2 1.6 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) pyroptosis(GO:0070269)
0.2 0.9 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.5 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 2.4 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.6 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.4 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.5 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 0.3 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.5 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 0.2 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.5 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.2 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.2 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.5 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.1 0.9 GO:0045176 apical protein localization(GO:0045176)
0.1 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.4 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.6 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.5 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.2 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.1 GO:2000974 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.1 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 1.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.4 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.6 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 1.8 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.8 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.5 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.3 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.5 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 1.1 GO:0009988 cell-cell recognition(GO:0009988)
0.0 0.0 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.1 GO:0045277 respiratory chain complex IV(GO:0045277) respiratory chain complex(GO:0098803)
0.1 0.4 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.4 GO:0097196 Shu complex(GO:0097196)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.5 GO:0001740 Barr body(GO:0001740)
0.1 0.5 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.6 GO:0030914 STAGA complex(GO:0030914)
0.0 0.5 GO:0043203 axon hillock(GO:0043203)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.2 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0016160 amylase activity(GO:0016160)
0.3 0.9 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.3 1.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.3 2.0 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.6 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.5 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 2.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.8 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 1.0 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 1.8 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 1.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.9 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 1.3 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.0 GO:0030366 molybdopterin synthase activity(GO:0030366)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID_MYC_PATHWAY C-MYC pathway
0.0 0.2 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 0.6 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.0 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 4.1 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.8 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.9 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.1 1.5 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.8 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.9 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.1 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation