Motif ID: POU6F2

Z-value: 0.652


Transcription factors associated with POU6F2:

Gene SymbolEntrez IDGene Name
POU6F2 ENSG00000106536.15 POU6F2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU6F2hg19_v2_chr7_+_39017504_39017598,
hg19_v2_chr7_+_39125365_39125489
0.096.7e-01Click!


Activity profile for motif POU6F2.

activity profile for motif POU6F2


Sorted Z-values histogram for motif POU6F2

Sorted Z-values for motif POU6F2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU6F2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_151646800 1.635 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr2_+_128403720 1.509 ENST00000272644.3
GPR17
G protein-coupled receptor 17
chr2_+_128403439 1.480 ENST00000544369.1
GPR17
G protein-coupled receptor 17
chr12_-_30887948 1.462 ENST00000433722.2
CAPRIN2
caprin family member 2
chr1_-_182641367 1.062 ENST00000508450.1
RGS8
regulator of G-protein signaling 8
chr5_-_139726181 0.964 ENST00000507104.1
ENST00000230990.6
HBEGF

heparin-binding EGF-like growth factor

chr10_+_94352956 0.957 ENST00000260731.3
KIF11
kinesin family member 11
chr14_+_32798547 0.854 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6


A kinase (PRKA) anchor protein 6


chr3_-_33686925 0.833 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2


cytoplasmic linker associated protein 2


chr12_+_15699286 0.824 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO



protein tyrosine phosphatase, receptor type, O



chr12_-_89746173 0.790 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr14_+_32798462 0.771 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr2_-_69098566 0.704 ENST00000295379.1
BMP10
bone morphogenetic protein 10
chr12_-_87232644 0.691 ENST00000549405.2
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr1_-_208417620 0.662 ENST00000367033.3
PLXNA2
plexin A2
chr3_+_159557637 0.647 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr6_-_32157947 0.637 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr22_+_30792846 0.619 ENST00000312932.9
ENST00000428195.1
SEC14L2

SEC14-like 2 (S. cerevisiae)

chr1_-_153123345 0.590 ENST00000368748.4
SPRR2G
small proline-rich protein 2G
chr10_+_120967072 0.574 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr2_-_216003127 0.569 ENST00000412081.1
ENST00000272895.7
ABCA12

ATP-binding cassette, sub-family A (ABC1), member 12

chr14_-_69261310 0.529 ENST00000336440.3
ZFP36L1
ZFP36 ring finger protein-like 1
chr7_-_83824169 0.482 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr6_-_87804815 0.464 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr8_+_22424551 0.464 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr4_+_66536248 0.462 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1

RP11-807H7.1

chr3_+_111717600 0.453 ENST00000273368.4
TAGLN3
transgelin 3
chr3_+_111718036 0.446 ENST00000455401.2
TAGLN3
transgelin 3
chr21_-_31864275 0.437 ENST00000334063.4
KRTAP19-3
keratin associated protein 19-3
chr17_-_19290483 0.433 ENST00000395592.2
ENST00000299610.4
MFAP4

microfibrillar-associated protein 4

chr6_+_29274403 0.432 ENST00000377160.2
OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr3_+_111717511 0.424 ENST00000478951.1
ENST00000393917.2
TAGLN3

transgelin 3

chr17_-_19290117 0.420 ENST00000497081.2
MFAP4
microfibrillar-associated protein 4
chr10_+_77056134 0.417 ENST00000528121.1
ENST00000416398.1
ZNF503-AS1

ZNF503 antisense RNA 1

chr6_+_25754927 0.386 ENST00000377905.4
ENST00000439485.2
SLC17A4

solute carrier family 17, member 4

chr5_-_156486120 0.382 ENST00000522693.1
HAVCR1
hepatitis A virus cellular receptor 1
chr3_-_33686743 0.376 ENST00000333778.6
ENST00000539981.1
CLASP2

cytoplasmic linker associated protein 2

chr8_+_39792474 0.354 ENST00000502986.2
IDO2
indoleamine 2,3-dioxygenase 2
chr13_+_78315466 0.353 ENST00000314070.5
ENST00000462234.1
SLAIN1

SLAIN motif family, member 1

chr17_-_39553844 0.335 ENST00000251645.2
KRT31
keratin 31
chr3_+_111718173 0.333 ENST00000494932.1
TAGLN3
transgelin 3
chr17_-_48133054 0.327 ENST00000499842.1
RP11-1094H24.4
RP11-1094H24.4
chr1_-_193028426 0.320 ENST00000367450.3
ENST00000530098.2
ENST00000367451.4
ENST00000367448.1
ENST00000367449.1
UCHL5




ubiquitin carboxyl-terminal hydrolase L5




chrX_-_106243451 0.313 ENST00000355610.4
ENST00000535534.1
MORC4

MORC family CW-type zinc finger 4

chr15_+_93443419 0.292 ENST00000557381.1
ENST00000420239.2
CHD2

chromodomain helicase DNA binding protein 2

chr17_-_33390667 0.290 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL


ring finger and FYVE-like domain containing E3 ubiquitin protein ligase


chr4_-_74486109 0.278 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr7_+_6655225 0.276 ENST00000457543.3
ZNF853
zinc finger protein 853
chr14_+_39583427 0.274 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
GEMIN2




gem (nuclear organelle) associated protein 2




chrX_+_43515467 0.265 ENST00000338702.3
ENST00000542639.1
MAOA

monoamine oxidase A

chr15_-_74421477 0.263 ENST00000514871.1
RP11-247C2.2
HCG2004779; Uncharacterized protein
chr3_+_189507523 0.263 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63




tumor protein p63




chr18_+_44812072 0.261 ENST00000598649.1
ENST00000586905.2
CTD-2130O13.1

CTD-2130O13.1

chr1_-_193028621 0.259 ENST00000367455.4
ENST00000367454.1
UCHL5

ubiquitin carboxyl-terminal hydrolase L5

chr20_+_56136136 0.250 ENST00000319441.4
ENST00000543666.1
PCK1

phosphoenolpyruvate carboxykinase 1 (soluble)

chr11_-_5364809 0.250 ENST00000300773.2
OR51B5
olfactory receptor, family 51, subfamily B, member 5
chr11_+_128563652 0.249 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr8_-_10512569 0.249 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr11_+_125034586 0.240 ENST00000298282.9
PKNOX2
PBX/knotted 1 homeobox 2
chr11_-_71823266 0.233 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15


anaphase promoting complex subunit 15


chr6_+_130339710 0.228 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3


l(3)mbt-like 3 (Drosophila)


chr10_-_23633720 0.226 ENST00000323327.4
C10orf67
chromosome 10 open reading frame 67
chr4_-_74486347 0.223 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr2_-_217559517 0.217 ENST00000449583.1
IGFBP5
insulin-like growth factor binding protein 5
chr4_+_78829479 0.213 ENST00000504901.1
MRPL1
mitochondrial ribosomal protein L1
chr22_-_32767017 0.211 ENST00000400234.1
RFPL3S
RFPL3 antisense
chr17_-_27418537 0.211 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr1_+_50574585 0.205 ENST00000371824.1
ENST00000371823.4
ELAVL4

ELAV like neuron-specific RNA binding protein 4

chr11_-_71823715 0.203 ENST00000545944.1
ENST00000502597.2
ANAPC15

anaphase promoting complex subunit 15

chr12_-_16761007 0.202 ENST00000354662.1
ENST00000441439.2
LMO3

LIM domain only 3 (rhombotin-like 2)

chr2_-_70780572 0.201 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr13_+_98612446 0.198 ENST00000496368.1
ENST00000421861.2
ENST00000357602.3
IPO5


importin 5


chr2_-_182545603 0.195 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr2_-_105030466 0.183 ENST00000449772.1
AC068535.3
AC068535.3
chrX_+_107288239 0.183 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr8_+_26150628 0.180 ENST00000523925.1
ENST00000315985.7
PPP2R2A

protein phosphatase 2, regulatory subunit B, alpha

chrX_+_107288197 0.178 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr12_-_71031185 0.177 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB


protein tyrosine phosphatase, receptor type, B


chr1_+_107683436 0.174 ENST00000370068.1
NTNG1
netrin G1
chr1_-_193028632 0.171 ENST00000421683.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr4_-_164395014 0.171 ENST00000280605.3
TKTL2
transketolase-like 2
chr7_-_80141328 0.168 ENST00000398291.3
GNAT3
guanine nucleotide binding protein, alpha transducing 3
chr7_-_14028488 0.163 ENST00000405358.4
ETV1
ets variant 1
chr1_+_50571949 0.163 ENST00000357083.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr11_-_71823796 0.162 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
ANAPC15





anaphase promoting complex subunit 15





chr4_-_74486217 0.160 ENST00000335049.5
ENST00000307439.5
RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chr11_+_31531291 0.159 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
ELP4


elongator acetyltransferase complex subunit 4


chr4_-_22444733 0.159 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chr7_+_141478242 0.159 ENST00000247881.2
TAS2R4
taste receptor, type 2, member 4
chr5_-_36301984 0.158 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L


RAN binding protein 3-like


chr3_+_189507432 0.157 ENST00000354600.5
TP63
tumor protein p63
chr5_+_115177178 0.156 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr1_+_107683644 0.154 ENST00000370067.1
NTNG1
netrin G1
chr7_-_14029283 0.153 ENST00000433547.1
ENST00000405192.2
ETV1

ets variant 1

chr5_-_140998616 0.149 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
DIAPH1





diaphanous-related formin 1





chr15_+_58702742 0.143 ENST00000356113.6
ENST00000414170.3
LIPC

lipase, hepatic

chr12_-_53045948 0.142 ENST00000309680.3
KRT2
keratin 2
chr7_+_115862858 0.129 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr11_-_36619771 0.126 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
RAG2


recombination activating gene 2


chr17_+_37784749 0.125 ENST00000394265.1
ENST00000394267.2
PPP1R1B

protein phosphatase 1, regulatory (inhibitor) subunit 1B

chr3_-_101039402 0.124 ENST00000193391.7
IMPG2
interphotoreceptor matrix proteoglycan 2
chrX_+_10031499 0.122 ENST00000454666.1
WWC3
WWC family member 3
chr6_-_155635583 0.118 ENST00000367166.4
TFB1M
transcription factor B1, mitochondrial
chr1_-_2458026 0.117 ENST00000435556.3
ENST00000378466.3
PANK4

pantothenate kinase 4

chr21_-_42219065 0.116 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr1_+_175036966 0.116 ENST00000239462.4
TNN
tenascin N
chr17_-_39471947 0.111 ENST00000334202.3
KRTAP17-1
keratin associated protein 17-1
chr3_+_141106458 0.109 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr4_+_175204818 0.104 ENST00000503780.1
CEP44
centrosomal protein 44kDa
chr5_-_140998481 0.104 ENST00000518047.1
DIAPH1
diaphanous-related formin 1
chr1_+_10271674 0.102 ENST00000377086.1
KIF1B
kinesin family member 1B
chr7_-_19184929 0.102 ENST00000275461.3
FERD3L
Fer3-like bHLH transcription factor
chr3_-_57199397 0.102 ENST00000296318.7
IL17RD
interleukin 17 receptor D
chr21_-_31869451 0.096 ENST00000334058.2
KRTAP19-4
keratin associated protein 19-4
chr10_-_102989551 0.092 ENST00000370193.2
LBX1
ladybird homeobox 1
chr10_+_18549645 0.088 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr11_-_31531121 0.088 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L






IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)






chr11_-_70672645 0.084 ENST00000423696.2
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr6_-_89927151 0.082 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr4_+_110749143 0.075 ENST00000317735.4
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr1_-_149900122 0.075 ENST00000271628.8
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr13_+_58206655 0.074 ENST00000377918.3
PCDH17
protocadherin 17
chr9_-_13165457 0.072 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ


multiple PDZ domain protein


chr9_+_109625378 0.071 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
ZNF462


zinc finger protein 462


chr17_-_29624343 0.069 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr5_+_126984710 0.069 ENST00000379445.3
CTXN3
cortexin 3
chr3_-_51909600 0.066 ENST00000446461.1
IQCF5
IQ motif containing F5
chr12_+_28410128 0.065 ENST00000381259.1
ENST00000381256.1
CCDC91

coiled-coil domain containing 91

chrX_-_19988382 0.062 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
CXorf23


chromosome X open reading frame 23


chrX_+_99839799 0.060 ENST00000373031.4
TNMD
tenomodulin
chrX_-_18690210 0.059 ENST00000379984.3
RS1
retinoschisin 1
chr12_-_52946923 0.059 ENST00000267119.5
KRT71
keratin 71
chr13_+_46039037 0.057 ENST00000349995.5
COG3
component of oligomeric golgi complex 3
chr6_-_33160231 0.055 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2









collagen, type XI, alpha 2









chrX_-_23926004 0.051 ENST00000379226.4
ENST00000379220.3
APOO

apolipoprotein O

chr13_-_103719196 0.046 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chrX_+_68835911 0.043 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
EDA





ectodysplasin A





chrX_-_30877837 0.042 ENST00000378930.3
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr10_-_92681033 0.040 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr8_+_77593448 0.040 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr12_+_54332535 0.038 ENST00000243056.3
HOXC13
homeobox C13
chr15_+_75080883 0.035 ENST00000567571.1
CSK
c-src tyrosine kinase
chr4_+_88571429 0.034 ENST00000339673.6
ENST00000282479.7
DMP1

dentin matrix acidic phosphoprotein 1

chr3_+_141105705 0.032 ENST00000513258.1
ZBTB38
zinc finger and BTB domain containing 38
chr12_-_71031220 0.032 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr17_-_40337470 0.031 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr9_-_21482312 0.031 ENST00000448696.3
IFNE
interferon, epsilon
chr11_-_63439013 0.030 ENST00000398868.3
ATL3
atlastin GTPase 3
chr8_+_77593474 0.029 ENST00000455469.2
ENST00000050961.6
ZFHX4

zinc finger homeobox 4

chr21_-_32253874 0.026 ENST00000332378.4
KRTAP11-1
keratin associated protein 11-1
chr10_+_35484793 0.025 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM




cAMP responsive element modulator




chr1_-_201140673 0.023 ENST00000367333.2
TMEM9
transmembrane protein 9
chr20_+_42187608 0.021 ENST00000373100.1
SGK2
serum/glucocorticoid regulated kinase 2
chr12_+_54348618 0.015 ENST00000243103.3
HOXC12
homeobox C12
chr4_+_40198527 0.011 ENST00000381799.5
RHOH
ras homolog family member H
chr15_+_80351977 0.011 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6



zinc finger, AN1-type domain 6



chr19_-_7698599 0.010 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr1_+_31883048 0.010 ENST00000536859.1
SERINC2
serine incorporator 2
chr3_+_77088989 0.009 ENST00000461745.1
ROBO2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr18_-_13915530 0.008 ENST00000327606.3
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr20_+_42187682 0.008 ENST00000373092.3
ENST00000373077.1
SGK2

serum/glucocorticoid regulated kinase 2

chr10_-_94257512 0.006 ENST00000371581.5
IDE
insulin-degrading enzyme
chr10_-_128210005 0.004 ENST00000284694.7
ENST00000454341.1
ENST00000432642.1
ENST00000392694.1
C10orf90



chromosome 10 open reading frame 90



chrX_+_86772787 0.004 ENST00000373114.4
KLHL4
kelch-like family member 4
chr17_-_10372875 0.002 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.3 1.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.3 0.8 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 1.0 GO:0051541 elastin metabolic process(GO:0051541)
0.2 3.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.2 0.5 GO:1904580 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.1 0.6 GO:0035627 ceramide transport(GO:0035627)
0.1 1.6 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.7 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.5 GO:0048880 sensory system development(GO:0048880)
0.1 1.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.6 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 1.1 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 0.7 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 1.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 1.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.7 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.4 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.6 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.1 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.1 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.5 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 1.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.9 GO:0071953 elastic fiber(GO:0071953)
0.1 0.6 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 1.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 1.0 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 0.6 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.2 0.6 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.6 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.1 0.4 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.7 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 3.0 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1 0.7 GO:0031433 telethonin binding(GO:0031433)
0.0 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0004802 transketolase activity(GO:0004802)
0.0 1.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 1.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.7 GO:0070628 proteasome binding(GO:0070628)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.7 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 1.1 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.8 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.0 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.0 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.3 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.7 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.1 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline