Motif ID: RFX3_RFX2

Z-value: 16.260

Transcription factors associated with RFX3_RFX2:

Gene SymbolEntrez IDGene Name
RFX2 ENSG00000087903.8 RFX2
RFX3 ENSG00000080298.11 RFX3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RFX2hg19_v2_chr19_-_6110474_61105510.993.9e-19Click!
RFX3hg19_v2_chr9_-_3525968_35260160.983.6e-16Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of RFX3_RFX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr21_-_43916433 212.143 ENST00000291536.3
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr21_-_43916296 202.607 ENST00000398352.3
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr1_-_109656439 176.549 ENST00000369949.4
C1orf194
chromosome 1 open reading frame 194
chr1_-_159869912 132.240 ENST00000368099.4
CCDC19
coiled-coil domain containing 19
chr16_-_67427389 120.512 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
TPPP3


tubulin polymerization-promoting protein family member 3


chr1_+_151682909 119.642 ENST00000326413.3
ENST00000442233.2
RIIAD1
AL589765.1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
Uncharacterized protein; cDNA FLJ36032 fis, clone TESTI2017069
chr22_+_23487513 111.673 ENST00000263116.2
ENST00000341989.4
RAB36

RAB36, member RAS oncogene family

chr17_-_6735035 107.897 ENST00000338694.2
TEKT1
tektin 1
chr17_-_6735012 107.533 ENST00000535086.1
TEKT1
tektin 1
chr15_+_71184931 105.183 ENST00000560369.1
ENST00000260382.5
LRRC49

leucine rich repeat containing 49

chr15_+_71185148 104.958 ENST00000443425.2
ENST00000560755.1
LRRC49

leucine rich repeat containing 49

chr2_+_228736321 104.810 ENST00000309931.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr17_-_74137374 103.205 ENST00000322957.6
FOXJ1
forkhead box J1
chr1_+_38022572 99.713 ENST00000541606.1
DNALI1
dynein, axonemal, light intermediate chain 1
chr6_+_43612750 98.256 ENST00000372165.4
ENST00000372163.4
RSPH9

radial spoke head 9 homolog (Chlamydomonas)

chr3_-_197676740 94.286 ENST00000452735.1
ENST00000453254.1
ENST00000455191.1
IQCG


IQ motif containing G


chr1_-_169396666 92.948 ENST00000456107.1
ENST00000367805.3
CCDC181

coiled-coil domain containing 181

chr2_+_228736335 92.752 ENST00000440997.1
ENST00000545118.1
DAW1

dynein assembly factor with WDR repeat domains 1

chr3_-_50383096 91.956 ENST00000442887.1
ENST00000360165.3
ZMYND10

zinc finger, MYND-type containing 10

chr11_+_111385497 91.352 ENST00000375618.4
ENST00000529167.1
ENST00000332814.6
C11orf88


chromosome 11 open reading frame 88


chr1_-_169396646 89.747 ENST00000367806.3
CCDC181
coiled-coil domain containing 181
chr1_+_38022513 89.206 ENST00000296218.7
DNALI1
dynein, axonemal, light intermediate chain 1
chr9_+_124922171 88.192 ENST00000373764.3
ENST00000536616.1
MORN5

MORN repeat containing 5

chr3_-_167098059 87.254 ENST00000392764.1
ENST00000474464.1
ENST00000392766.2
ENST00000485651.1
ZBBX



zinc finger, B-box domain containing



chrX_-_48693955 86.733 ENST00000218230.5
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr2_-_130902567 86.726 ENST00000457413.1
ENST00000392984.3
ENST00000409128.1
ENST00000441670.1
ENST00000409943.3
ENST00000409234.3
ENST00000310463.6
CCDC74B






coiled-coil domain containing 74B






chr11_+_101918153 85.376 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70


chromosome 11 open reading frame 70


chr2_+_132285406 84.141 ENST00000295171.6
ENST00000409856.3
CCDC74A

coiled-coil domain containing 74A

chr7_+_48075108 83.445 ENST00000420324.1
ENST00000435376.1
ENST00000430738.1
ENST00000348904.3
ENST00000539619.1
C7orf57




chromosome 7 open reading frame 57




chr12_+_7014064 80.133 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr17_+_9479944 79.168 ENST00000396219.3
ENST00000352665.5
WDR16

WD repeat domain 16

chr1_+_217804661 78.522 ENST00000366933.4
SPATA17
spermatogenesis associated 17
chrX_+_106449862 77.270 ENST00000372453.3
ENST00000535523.1
PIH1D3

PIH1 domain containing 3

chr1_+_151693984 76.878 ENST00000479191.1
RIIAD1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
chr8_-_49647791 75.764 ENST00000262103.3
ENST00000523092.1
ENST00000433756.1
EFCAB1


EF-hand calcium binding domain 1


chr11_-_75379612 75.496 ENST00000526740.1
MAP6
microtubule-associated protein 6
chr6_+_52285131 74.685 ENST00000433625.2
EFHC1
EF-hand domain (C-terminal) containing 1
chr11_+_94245617 74.014 ENST00000542198.1
RP11-867G2.2
long intergenic non-protein coding RNA 1171
chr12_+_7013897 73.268 ENST00000007969.8
ENST00000323702.5
LRRC23

leucine rich repeat containing 23

chr16_-_75590114 70.791 ENST00000568377.1
ENST00000565067.1
ENST00000258173.6
TMEM231


transmembrane protein 231


chr15_+_82555125 70.655 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B



family with sequence similarity 154, member B



chr12_-_58329819 69.975 ENST00000551421.1
RP11-620J15.3
RP11-620J15.3
chr1_-_36916066 68.923 ENST00000315643.9
OSCP1
organic solute carrier partner 1
chr11_-_111944895 68.747 ENST00000431456.1
ENST00000280350.4
ENST00000530641.1
PIH1D2


PIH1 domain containing 2


chr11_-_111944704 68.047 ENST00000532211.1
PIH1D2
PIH1 domain containing 2
chr15_+_43803143 67.991 ENST00000382031.1
MAP1A
microtubule-associated protein 1A
chr6_+_116937636 67.984 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
RSPH4A


radial spoke head 4 homolog A (Chlamydomonas)


chr11_-_8615507 67.447 ENST00000431279.2
ENST00000418597.1
STK33

serine/threonine kinase 33

chr12_+_7014126 67.095 ENST00000415834.1
ENST00000436789.1
LRRC23

leucine rich repeat containing 23

chr3_-_169530574 66.577 ENST00000316515.7
ENST00000522830.1
ENST00000522526.2
LRRC34


leucine rich repeat containing 34


chr3_-_169530452 65.481 ENST00000446859.1
LRRC34
leucine rich repeat containing 34
chr16_+_84178874 64.822 ENST00000378553.5
DNAAF1
dynein, axonemal, assembly factor 1
chr6_+_112408768 61.617 ENST00000368656.2
ENST00000604268.1
FAM229B

family with sequence similarity 229, member B

chr4_-_177116772 61.562 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr15_+_81426588 61.118 ENST00000286732.4
C15orf26
chromosome 15 open reading frame 26
chr6_-_109761707 60.219 ENST00000520723.1
ENST00000518648.1
ENST00000417394.2
PPIL6


peptidylprolyl isomerase (cyclophilin)-like 6


chr20_-_3762087 57.707 ENST00000379756.3
SPEF1
sperm flagellar 1
chr1_-_183622442 57.204 ENST00000308641.4
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr16_+_57728701 56.947 ENST00000569375.1
ENST00000360716.3
ENST00000569167.1
ENST00000394337.4
ENST00000563126.1
ENST00000336825.8
CCDC135





coiled-coil domain containing 135





chr16_+_58283814 56.919 ENST00000443128.2
ENST00000219299.4
CCDC113

coiled-coil domain containing 113

chr16_+_67840986 56.264 ENST00000561639.1
ENST00000567852.1
ENST00000565148.1
ENST00000388833.3
ENST00000561654.1
ENST00000431934.2
TSNAXIP1





translin-associated factor X interacting protein 1





chr10_+_63422695 55.182 ENST00000330194.2
ENST00000389639.3
C10orf107

chromosome 10 open reading frame 107

chr1_+_109656719 55.089 ENST00000457623.2
ENST00000529753.1
KIAA1324

KIAA1324

chr16_+_67840668 54.958 ENST00000415766.3
TSNAXIP1
translin-associated factor X interacting protein 1
chr1_-_67390474 54.800 ENST00000371023.3
ENST00000371022.3
ENST00000371026.3
ENST00000431318.1
WDR78



WD repeat domain 78



chr6_-_165723088 54.593 ENST00000230301.8
C6orf118
chromosome 6 open reading frame 118
chr1_+_111888890 53.896 ENST00000369738.4
PIFO
primary cilia formation
chr1_+_111889212 53.596 ENST00000369737.4
PIFO
primary cilia formation
chr15_-_55790515 52.932 ENST00000448430.2
ENST00000457155.2
DYX1C1

dyslexia susceptibility 1 candidate 1

chr3_-_107941209 52.884 ENST00000492106.1
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr2_+_74648848 52.716 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WDR54


WD repeat domain 54


chr6_-_43478239 52.553 ENST00000372441.1
LRRC73
leucine rich repeat containing 73
chr10_-_25305011 52.379 ENST00000331161.4
ENST00000376363.1
ENKUR

enkurin, TRPC channel interacting protein

chr6_+_52285046 52.292 ENST00000371068.5
EFHC1
EF-hand domain (C-terminal) containing 1
chr14_+_74486043 51.909 ENST00000464394.1
ENST00000394009.3
CCDC176

coiled-coil domain containing 176

chr1_-_36915880 51.623 ENST00000445843.3
OSCP1
organic solute carrier partner 1
chr13_+_31506818 51.535 ENST00000380473.3
TEX26
testis expressed 26
chr7_+_76751926 51.385 ENST00000285871.4
ENST00000431197.1
CCDC146

coiled-coil domain containing 146

chr3_+_158288942 50.856 ENST00000491767.1
ENST00000355893.5
MLF1

myeloid leukemia factor 1

chr16_-_30773372 50.221 ENST00000545825.1
ENST00000541260.1
C16orf93

chromosome 16 open reading frame 93

chr17_+_62075703 49.902 ENST00000577953.1
ENST00000582540.1
ENST00000579184.1
ENST00000425164.3
ENST00000412177.1
ENST00000539996.1
ENST00000583891.1
ENST00000580752.1
C17orf72







chromosome 17 open reading frame 72







chr3_+_158288960 49.684 ENST00000484955.1
ENST00000359117.5
ENST00000498592.1
ENST00000477042.1
ENST00000471745.1
ENST00000469452.1
MLF1





myeloid leukemia factor 1





chr1_-_114301755 49.179 ENST00000393357.2
ENST00000369596.2
ENST00000446739.1
PHTF1


putative homeodomain transcription factor 1


chr12_-_58329888 49.150 ENST00000546580.1
RP11-620J15.3
RP11-620J15.3
chr1_+_161068179 48.814 ENST00000368011.4
ENST00000392192.2
KLHDC9

kelch domain containing 9

chr15_-_68497657 48.294 ENST00000448060.2
ENST00000467889.1
CALML4

calmodulin-like 4

chr1_+_245133278 47.864 ENST00000366522.2
EFCAB2
EF-hand calcium binding domain 2
chr7_-_100965011 47.823 ENST00000498704.2
ENST00000517481.1
ENST00000437644.2
ENST00000315322.4
RABL5



RAB, member RAS oncogene family-like 5



chr17_+_7761301 47.152 ENST00000332439.4
ENST00000570446.1
CYB5D1

cytochrome b5 domain containing 1

chr9_+_135754263 46.553 ENST00000356311.5
ENST00000350499.6
C9orf9

chromosome 9 open reading frame 9

chr10_+_22634384 46.413 ENST00000376624.3
ENST00000376603.2
ENST00000376601.1
ENST00000538630.1
ENST00000456231.2
ENST00000313311.6
ENST00000435326.1
SPAG6






sperm associated antigen 6






chr6_+_109169591 46.320 ENST00000368972.3
ENST00000392644.4
ARMC2

armadillo repeat containing 2

chr11_+_61276214 46.253 ENST00000378075.2
LRRC10B
leucine rich repeat containing 10B
chr1_+_109656579 45.875 ENST00000526264.1
ENST00000369939.3
KIAA1324

KIAA1324

chr1_-_36916011 45.773 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
OSCP1


organic solute carrier partner 1


chr7_+_138818490 45.661 ENST00000430935.1
ENST00000495038.1
ENST00000474035.2
ENST00000478836.2
ENST00000464848.1
ENST00000343187.4
TTC26





tetratricopeptide repeat domain 26





chr2_+_39103103 44.964 ENST00000340556.6
ENST00000410014.1
ENST00000409665.1
ENST00000409077.2
ENST00000409131.2
MORN2




MORN repeat containing 2




chr17_+_260097 44.771 ENST00000360127.6
ENST00000571106.1
ENST00000491373.1
C17orf97


chromosome 17 open reading frame 97


chr11_-_8615720 44.760 ENST00000358872.3
ENST00000454443.2
STK33

serine/threonine kinase 33

chr11_-_8615488 44.354 ENST00000315204.1
ENST00000396672.1
ENST00000396673.1
STK33


serine/threonine kinase 33


chr3_+_158288999 44.010 ENST00000482628.1
ENST00000478894.2
ENST00000392822.3
ENST00000466246.1
MLF1



myeloid leukemia factor 1



chr3_+_97483572 43.566 ENST00000335979.2
ENST00000394206.1
ARL6

ADP-ribosylation factor-like 6

chr3_-_129147432 42.740 ENST00000503957.1
ENST00000505956.1
ENST00000326085.3
EFCAB12


EF-hand calcium binding domain 12


chr1_-_118727781 42.097 ENST00000336338.5
SPAG17
sperm associated antigen 17
chr19_-_55677999 41.926 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
DNAAF3


dynein, axonemal, assembly factor 3


chr3_+_97483366 41.784 ENST00000463745.1
ENST00000462412.1
ARL6

ADP-ribosylation factor-like 6

chr12_+_122356488 41.769 ENST00000397454.2
WDR66
WD repeat domain 66
chr19_-_55677920 41.561 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3


dynein, axonemal, assembly factor 3


chrX_+_119030118 41.084 ENST00000371422.1
ENST00000334356.2
AKAP14

A kinase (PRKA) anchor protein 14

chr1_-_48937838 40.830 ENST00000371847.3
SPATA6
spermatogenesis associated 6
chr22_-_38349552 40.645 ENST00000422191.1
ENST00000249079.2
ENST00000418863.1
ENST00000403305.1
ENST00000403026.1
C22orf23




chromosome 22 open reading frame 23




chr1_-_114302086 40.466 ENST00000369604.1
ENST00000357783.2
PHTF1

putative homeodomain transcription factor 1

chr3_-_57530051 40.430 ENST00000311202.6
ENST00000351747.2
ENST00000495027.1
ENST00000389536.4
DNAH12



dynein, axonemal, heavy chain 12



chr14_+_100259666 40.286 ENST00000262233.6
ENST00000334192.4
EML1

echinoderm microtubule associated protein like 1

chr2_+_170335924 40.215 ENST00000554017.1
ENST00000392663.2
ENST00000513963.1
BBS5

RP11-724O16.1
Bardet-Biedl syndrome 5

Bardet-Biedl syndrome 5 protein; Uncharacterized protein
chr1_-_114301960 40.008 ENST00000369598.1
ENST00000369600.1
PHTF1

putative homeodomain transcription factor 1

chr3_-_47324079 39.889 ENST00000352910.4
KIF9
kinesin family member 9
chr8_-_133687813 39.798 ENST00000250173.1
ENST00000519595.1
LRRC6

leucine rich repeat containing 6

chrX_+_119029800 39.352 ENST00000371431.3
ENST00000371423.2
ENST00000371425.4
ENST00000394594.2
AKAP14



A kinase (PRKA) anchor protein 14



chr3_-_47324242 38.369 ENST00000456548.1
ENST00000432493.1
ENST00000335044.2
ENST00000444589.2
KIF9



kinesin family member 9



chr7_-_102715263 38.003 ENST00000379305.3
FBXL13
F-box and leucine-rich repeat protein 13
chr18_+_44526786 37.901 ENST00000245121.5
ENST00000356157.7
KATNAL2

katanin p60 subunit A-like 2

chr1_+_20512568 37.679 ENST00000375099.3
UBXN10
UBX domain protein 10
chr17_+_11501748 37.610 ENST00000262442.4
ENST00000579828.1
DNAH9

dynein, axonemal, heavy chain 9

chr7_-_102715172 37.572 ENST00000456695.1
ENST00000455112.2
ENST00000440067.1
FBXL13


F-box and leucine-rich repeat protein 13


chr2_+_120301997 37.448 ENST00000602047.1
PCDP1
Primary ciliary dyskinesia protein 1
chr2_+_120302041 37.272 ENST00000442513.3
ENST00000413369.3
PCDP1

Primary ciliary dyskinesia protein 1

chr11_-_62473706 37.049 ENST00000403550.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr3_-_107941230 37.024 ENST00000264538.3
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr1_-_173638976 36.827 ENST00000333279.2
ANKRD45
ankyrin repeat domain 45
chr8_-_133687778 36.727 ENST00000518642.1
LRRC6
leucine rich repeat containing 6
chr19_-_7990991 36.326 ENST00000318978.4
CTXN1
cortexin 1
chr3_-_47324008 35.583 ENST00000425853.1
KIF9
kinesin family member 9
chr3_-_196439065 35.179 ENST00000399942.4
ENST00000409690.3
CEP19

centrosomal protein 19kDa

chr16_+_57406368 34.315 ENST00000006053.6
ENST00000563383.1
CX3CL1

chemokine (C-X3-C motif) ligand 1

chr17_-_56406117 34.253 ENST00000268893.6
ENST00000355701.3
BZRAP1

benzodiazepine receptor (peripheral) associated protein 1

chr16_+_4784458 34.085 ENST00000590191.1
C16orf71
chromosome 16 open reading frame 71
chr18_+_77905894 33.817 ENST00000589574.1
ENST00000588226.1
ENST00000585422.1
AC139100.2


Uncharacterized protein


chr1_-_114301503 33.747 ENST00000447664.2
PHTF1
putative homeodomain transcription factor 1
chr9_-_117111222 33.390 ENST00000374079.4
AKNA
AT-hook transcription factor
chr18_-_71815051 33.290 ENST00000582526.1
ENST00000419743.2
FBXO15

F-box protein 15

chr3_-_19975665 33.289 ENST00000295824.9
ENST00000389256.4
EFHB

EF-hand domain family, member B

chr18_-_71814999 33.059 ENST00000269500.5
FBXO15
F-box protein 15
chr18_-_47792851 32.974 ENST00000398545.4
CCDC11
coiled-coil domain containing 11
chr2_-_178483694 32.465 ENST00000355689.5
TTC30A
tetratricopeptide repeat domain 30A
chr22_-_38240412 32.028 ENST00000215941.4
ANKRD54
ankyrin repeat domain 54
chr8_+_144798429 31.029 ENST00000338033.4
ENST00000395107.4
ENST00000395108.2
MAPK15


mitogen-activated protein kinase 15


chr1_+_183605200 31.007 ENST00000304685.4
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr20_+_43160458 30.983 ENST00000372889.1
ENST00000372887.1
ENST00000372882.3
PKIG


protein kinase (cAMP-dependent, catalytic) inhibitor gamma


chr11_-_62473776 30.906 ENST00000278893.7
ENST00000407022.3
ENST00000421906.1
BSCL2


Berardinelli-Seip congenital lipodystrophy 2 (seipin)


chr2_-_230579185 30.759 ENST00000341772.4
DNER
delta/notch-like EGF repeat containing
chr20_+_43160409 30.534 ENST00000372894.3
ENST00000372892.3
ENST00000372891.3
PKIG


protein kinase (cAMP-dependent, catalytic) inhibitor gamma


chr3_-_113160334 29.833 ENST00000393845.2
ENST00000295868.2
WDR52

WD repeat domain 52

chr2_-_241497374 29.310 ENST00000373318.2
ENST00000406958.1
ENST00000391987.1
ENST00000373320.4
ANKMY1



ankyrin repeat and MYND domain containing 1



chr4_+_40751914 29.198 ENST00000381782.2
ENST00000316607.5
NSUN7

NOP2/Sun domain family, member 7

chr3_-_47324060 29.140 ENST00000452770.2
KIF9
kinesin family member 9
chr22_+_39052632 29.135 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1



chibby homolog 1 (Drosophila)



chr12_+_6930964 29.089 ENST00000382315.3
GPR162
G protein-coupled receptor 162
chr1_+_63989004 28.983 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr21_-_40817645 28.768 ENST00000438404.1
ENST00000358268.2
ENST00000411566.1
ENST00000451131.1
ENST00000418018.1
ENST00000415863.1
ENST00000426783.1
ENST00000288350.3
ENST00000485895.2
ENST00000448288.2
ENST00000456017.1
ENST00000434281.1
LCA5L











Leber congenital amaurosis 5-like











chr3_-_27410847 28.356 ENST00000429845.2
ENST00000341435.5
ENST00000435750.1
NEK10


NIMA-related kinase 10


chr5_-_54529415 28.219 ENST00000282572.4
CCNO
cyclin O
chr3_+_119421849 28.191 ENST00000273390.5
ENST00000463700.1
MAATS1

MYCBP-associated, testis expressed 1

chr15_+_67547163 28.090 ENST00000335894.4
IQCH
IQ motif containing H
chr11_+_111807863 27.715 ENST00000440460.2
DIXDC1
DIX domain containing 1
chr9_-_135754164 27.622 ENST00000298545.3
AK8
adenylate kinase 8
chr9_+_100069933 27.595 ENST00000529487.1
CCDC180
coiled-coil domain containing 180
chr1_-_48937821 27.578 ENST00000396199.3
SPATA6
spermatogenesis associated 6
chr21_-_34185944 27.554 ENST00000479548.1
C21orf62
chromosome 21 open reading frame 62
chr1_-_24740207 27.544 ENST00000003583.8
ENST00000337248.4
STPG1

sperm-tail PG-rich repeat containing 1

chr22_-_31063782 27.426 ENST00000404885.1
ENST00000403268.1
ENST00000407308.1
ENST00000342474.4
ENST00000334679.3
DUSP18




dual specificity phosphatase 18




chr3_-_113775328 27.404 ENST00000483766.1
ENST00000545063.1
ENST00000491000.1
ENST00000295878.3
KIAA1407



KIAA1407



chr10_+_104178946 27.348 ENST00000432590.1
FBXL15
F-box and leucine-rich repeat protein 15
chr16_+_3550924 26.849 ENST00000576634.1
ENST00000574369.1
ENST00000341633.5
ENST00000417763.2
ENST00000571025.1
CLUAP1




clusterin associated protein 1




chr2_-_178417742 26.841 ENST00000408939.3
TTC30B
tetratricopeptide repeat domain 30B
chr1_-_169337176 26.839 ENST00000472647.1
ENST00000367811.3
NME7

NME/NM23 family member 7

chr2_+_159651821 26.512 ENST00000309950.3
ENST00000409042.1
DAPL1

death associated protein-like 1

chr7_+_133812052 26.427 ENST00000285928.2
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chr13_+_37005967 26.387 ENST00000440264.1
ENST00000449823.1
CCNA1

cyclin A1

chr10_+_127585093 26.213 ENST00000368695.1
ENST00000368693.1
FANK1

fibronectin type III and ankyrin repeat domains 1

chr16_-_67450325 25.847 ENST00000348579.2
ZDHHC1
zinc finger, DHHC-type containing 1
chr12_-_63328817 25.791 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr11_+_537494 25.448 ENST00000270115.7
LRRC56
leucine rich repeat containing 56
chr11_-_8615687 25.315 ENST00000534493.1
ENST00000422559.2
STK33

serine/threonine kinase 33

chr19_-_50529193 25.287 ENST00000596445.1
ENST00000599538.1
VRK3

vaccinia related kinase 3

chr9_-_131418944 25.070 ENST00000419989.1
ENST00000451652.1
ENST00000372715.2
WDR34


WD repeat domain 34


chr7_+_102073966 25.061 ENST00000495936.1
ENST00000356387.2
ENST00000478730.2
ENST00000468241.1
ENST00000403646.3
ORAI2




ORAI calcium release-activated calcium modulator 2




chr11_-_75379479 24.663 ENST00000434603.2
MAP6
microtubule-associated protein 6
chr10_-_75118611 24.434 ENST00000355577.3
ENST00000394865.1
ENST00000310715.3
ENST00000401621.2
TTC18



tetratricopeptide repeat domain 18



chr11_-_119252359 24.245 ENST00000455332.2
USP2
ubiquitin specific peptidase 2
chr10_-_75118471 24.243 ENST00000340329.3
TTC18
tetratricopeptide repeat domain 18
chr3_-_196045127 24.165 ENST00000325318.5
TCTEX1D2
Tctex1 domain containing 2
chr7_+_129142320 24.123 ENST00000462322.2
SMKR1
small lysine-rich protein 1
chr19_+_10527449 24.067 ENST00000592685.1
ENST00000380702.2
PDE4A

phosphodiesterase 4A, cAMP-specific

chr1_-_48937682 24.064 ENST00000371843.3
SPATA6
spermatogenesis associated 6
chr6_+_109761898 23.968 ENST00000258052.3
SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr19_+_35630926 23.899 ENST00000588081.1
ENST00000589121.1
FXYD1

FXYD domain containing ion transport regulator 1

chr19_-_41870026 23.529 ENST00000243578.3
B9D2
B9 protein domain 2
chr10_+_134973905 23.427 ENST00000304613.3
ENST00000368572.2
KNDC1

kinase non-catalytic C-lobe domain (KIND) containing 1

chr9_+_127615733 23.326 ENST00000373574.1
WDR38
WD repeat domain 38

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
34.4 103.2 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
22.5 90.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
21.8 239.9 GO:0060294 cilium movement involved in cell motility(GO:0060294)
21.1 675.2 GO:0044458 motile cilium assembly(GO:0044458)
15.4 92.4 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
15.2 743.2 GO:0035082 axoneme assembly(GO:0035082)
11.4 34.3 GO:0050902 leukocyte adhesive activation(GO:0050902)
10.3 30.8 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
8.8 193.5 GO:0003341 cilium movement(GO:0003341)
8.6 77.4 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
6.5 19.5 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
6.1 24.3 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
6.0 102.5 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
5.8 291.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
5.4 43.2 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
5.3 21.3 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
4.9 44.5 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
4.9 29.1 GO:1903575 cornified envelope assembly(GO:1903575)
4.8 14.3 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
4.1 45.4 GO:0042073 intraciliary transport(GO:0042073)
4.1 78.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
4.0 47.7 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
3.8 22.7 GO:0018095 protein polyglutamylation(GO:0018095)
3.6 135.4 GO:0071801 regulation of podosome assembly(GO:0071801)
3.1 27.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
3.0 47.3 GO:0045475 locomotor rhythm(GO:0045475)
2.9 23.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
2.9 34.8 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
2.8 17.0 GO:0070560 protein secretion by platelet(GO:0070560)
2.8 16.9 GO:0001757 somite specification(GO:0001757)
2.8 86.7 GO:0002021 response to dietary excess(GO:0002021)
2.6 122.1 GO:0048741 skeletal muscle fiber development(GO:0048741)
2.6 15.6 GO:0031392 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
2.6 113.1 GO:0001578 microtubule bundle formation(GO:0001578)
2.4 19.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
2.4 29.3 GO:0006228 UTP biosynthetic process(GO:0006228)
2.4 17.1 GO:0044375 regulation of peroxisome size(GO:0044375)
2.4 9.7 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
2.4 4.8 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
2.4 16.8 GO:0007258 JUN phosphorylation(GO:0007258)
2.3 246.1 GO:0007368 determination of left/right symmetry(GO:0007368)
2.3 6.8 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
2.2 8.9 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
2.2 17.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
2.2 19.4 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
2.1 29.9 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
2.1 12.5 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
2.0 8.1 GO:0035026 leading edge cell differentiation(GO:0035026)
2.0 8.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
2.0 8.0 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
2.0 55.5 GO:0034389 lipid particle organization(GO:0034389)
1.9 58.9 GO:0007141 male meiosis I(GO:0007141)
1.9 7.5 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
1.8 25.1 GO:0002115 store-operated calcium entry(GO:0002115)
1.7 27.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
1.7 33.5 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
1.7 8.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
1.6 3.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
1.6 35.4 GO:1904355 positive regulation of telomere capping(GO:1904355)
1.6 22.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
1.5 4.6 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
1.5 104.9 GO:0021795 cerebral cortex cell migration(GO:0021795)
1.5 14.8 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
1.5 5.9 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
1.5 33.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
1.4 26.9 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
1.4 4.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
1.3 16.9 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
1.3 159.5 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
1.2 278.9 GO:0060271 cilium morphogenesis(GO:0060271)
1.1 22.3 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
1.1 3.3 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
1.1 60.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
1.0 27.6 GO:0021591 ventricular system development(GO:0021591)
0.9 8.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.9 25.8 GO:0018345 protein palmitoylation(GO:0018345)
0.9 87.9 GO:0032418 lysosome localization(GO:0032418)
0.9 8.5 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.8 7.9 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.8 32.0 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.8 17.0 GO:2001222 regulation of neuron migration(GO:2001222)
0.8 24.5 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.8 7.6 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.8 3.0 GO:0060849 radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.7 2.2 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.7 2.9 GO:0072553 terminal button organization(GO:0072553)
0.7 35.7 GO:0007405 neuroblast proliferation(GO:0007405)
0.7 3.6 GO:1904764 regulation of fibril organization(GO:1902903) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.7 0.7 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.7 27.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.7 0.7 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.7 4.6 GO:0070933 histone H4 deacetylation(GO:0070933)
0.6 20.6 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.6 1.9 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.6 12.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.6 6.0 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.6 85.5 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.6 17.6 GO:0007035 vacuolar acidification(GO:0007035)
0.6 7.0 GO:0015886 heme transport(GO:0015886)
0.6 5.2 GO:0032264 IMP salvage(GO:0032264)
0.6 2.9 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.6 27.0 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.6 7.3 GO:0001302 replicative cell aging(GO:0001302)
0.5 2.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.5 71.2 GO:0007286 spermatid development(GO:0007286)
0.5 6.5 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.5 5.7 GO:0032782 bile acid secretion(GO:0032782)
0.5 13.8 GO:0001975 response to amphetamine(GO:0001975)
0.5 7.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.5 13.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.5 33.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.5 15.2 GO:0016574 histone ubiquitination(GO:0016574)
0.5 6.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.5 11.3 GO:0006953 acute-phase response(GO:0006953)
0.4 35.4 GO:0009060 aerobic respiration(GO:0009060)
0.4 13.7 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.4 53.5 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.4 6.9 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.4 20.4 GO:0006298 mismatch repair(GO:0006298)
0.4 5.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.4 8.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.3 6.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.3 41.3 GO:0022900 electron transport chain(GO:0022900)
0.3 3.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.3 35.2 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.3 3.9 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.3 2.1 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.3 2.9 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.3 7.3 GO:0035357 peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.3 5.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.3 16.5 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.3 1.6 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.3 5.2 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.3 9.4 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.3 1.5 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.3 4.8 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.2 2.5 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.2 9.7 GO:0010107 potassium ion import(GO:0010107)
0.2 7.2 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.2 6.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 1.4 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.2 5.4 GO:0016578 histone deubiquitination(GO:0016578)
0.2 70.0 GO:0000209 protein polyubiquitination(GO:0000209)
0.2 3.5 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.2 8.5 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.2 1.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 2.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 3.2 GO:0006004 fucose metabolic process(GO:0006004)
0.1 64.7 GO:0007283 spermatogenesis(GO:0007283)
0.1 8.2 GO:0015701 bicarbonate transport(GO:0015701)
0.1 2.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.5 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 3.3 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.1 3.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 1.5 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 4.2 GO:0008038 neuron recognition(GO:0008038)
0.1 2.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 2.8 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 8.0 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 2.0 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1 0.7 GO:0006361 transcription from RNA polymerase I promoter(GO:0006360) transcription initiation from RNA polymerase I promoter(GO:0006361) transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.1 0.4 GO:0036491 regulation of translation in response to endoplasmic reticulum stress(GO:0036490) regulation of translation initiation in response to endoplasmic reticulum stress(GO:0036491) eiF2alpha phosphorylation in response to endoplasmic reticulum stress(GO:0036492) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1 52.5 GO:0031344 regulation of cell projection organization(GO:0031344)
0.1 17.6 GO:0045444 fat cell differentiation(GO:0045444)
0.1 10.8 GO:1901796 regulation of signal transduction by p53 class mediator(GO:1901796)
0.1 0.6 GO:0046325 negative regulation of glucose import(GO:0046325)
0.1 0.9 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 12.2 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.1 2.0 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 2.3 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 2.2 GO:0042407 inner mitochondrial membrane organization(GO:0007007) cristae formation(GO:0042407)
0.1 1.7 GO:0035902 response to immobilization stress(GO:0035902)
0.1 0.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 2.6 GO:0016925 protein sumoylation(GO:0016925)
0.1 4.1 GO:0015914 phospholipid transport(GO:0015914)
0.1 0.3 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 1.3 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 1.3 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 1.1 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 1.1 GO:0006379 mRNA cleavage(GO:0006379)
0.0 1.0 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.3 GO:0007098 centrosome cycle(GO:0007098)
0.0 1.1 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773)
0.0 1.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.6 GO:0045454 cell redox homeostasis(GO:0045454)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
46.0 137.9 GO:0001534 radial spoke(GO:0001534)
43.3 303.4 GO:0002177 manchette(GO:0002177)
34.6 414.8 GO:0072687 meiotic spindle(GO:0072687)
24.8 123.8 GO:0005879 axonemal microtubule(GO:0005879)
23.1 92.5 GO:0097224 sperm connecting piece(GO:0097224)
18.8 56.3 GO:1990716 axonemal central apparatus(GO:1990716)
11.8 58.9 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
11.2 112.3 GO:0097427 microtubule bundle(GO:0097427)
10.9 314.9 GO:0030992 intraciliary transport particle B(GO:0030992)
10.0 39.8 GO:0016939 kinesin II complex(GO:0016939)
9.6 182.8 GO:0036038 MKS complex(GO:0036038)
8.9 44.5 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
8.1 24.2 GO:0031021 interphase microtubule organizing center(GO:0031021)
7.7 84.9 GO:0034464 BBSome(GO:0034464)
7.1 792.7 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
6.6 192.4 GO:0034451 centriolar satellite(GO:0034451)
5.9 17.6 GO:0043291 RAVE complex(GO:0043291)
4.4 21.8 GO:1990769 proximal neuron projection(GO:1990769)
4.1 95.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
3.4 30.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
3.1 166.3 GO:0009925 basal plasma membrane(GO:0009925)
3.1 36.8 GO:0001520 outer dense fiber(GO:0001520)
2.8 39.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
2.4 2.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
2.2 188.6 GO:0036126 sperm flagellum(GO:0036126)
2.2 134.7 GO:0005801 cis-Golgi network(GO:0005801)
2.1 21.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
2.1 16.9 GO:0044294 dendritic growth cone(GO:0044294)
2.0 18.3 GO:1990023 mitotic spindle midzone(GO:1990023)
1.9 135.4 GO:0002102 podosome(GO:0002102)
1.8 15.9 GO:0097542 ciliary tip(GO:0097542)
1.6 128.2 GO:0036064 ciliary basal body(GO:0036064)
1.5 10.8 GO:0000137 Golgi cis cisterna(GO:0000137)
1.5 7.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
1.4 40.2 GO:0071682 endocytic vesicle lumen(GO:0071682)
1.3 8.8 GO:0000138 Golgi trans cisterna(GO:0000138)
1.1 89.4 GO:0005814 centriole(GO:0005814)
1.1 20.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
1.1 362.0 GO:0005929 cilium(GO:0005929)
1.0 8.1 GO:0035976 AP1 complex(GO:0035976)
1.0 15.2 GO:0035102 PRC1 complex(GO:0035102)
0.9 17.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.9 19.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.9 68.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.9 13.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.8 10.8 GO:0000242 pericentriolar material(GO:0000242)
0.8 5.3 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.7 74.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.6 51.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.6 1.3 GO:0033565 ESCRT-0 complex(GO:0033565)
0.6 6.0 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.6 4.8 GO:0043196 varicosity(GO:0043196)
0.6 17.1 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.5 239.8 GO:0005874 microtubule(GO:0005874)
0.5 8.0 GO:0044232 organelle membrane contact site(GO:0044232)
0.5 90.9 GO:0031902 late endosome membrane(GO:0031902)
0.5 5.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.5 5.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.5 3.6 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.5 21.5 GO:0035861 site of double-strand break(GO:0035861)
0.5 3.3 GO:0070847 core mediator complex(GO:0070847)
0.4 21.0 GO:0016235 aggresome(GO:0016235)
0.4 1.6 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.4 58.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.4 6.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.4 1.9 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.4 56.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.4 24.0 GO:0005901 caveola(GO:0005901)
0.3 109.0 GO:0005813 centrosome(GO:0005813)
0.3 4.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.3 5.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 29.5 GO:1902911 protein kinase complex(GO:1902911)
0.3 16.1 GO:0031201 SNARE complex(GO:0031201)
0.3 5.1 GO:0000421 autophagosome membrane(GO:0000421)
0.2 8.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 170.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.2 2.5 GO:0031143 pseudopodium(GO:0031143)
0.2 23.4 GO:0030426 growth cone(GO:0030426)
0.2 0.7 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 1.7 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 2.9 GO:0005771 multivesicular body(GO:0005771)
0.1 2.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 8.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 8.9 GO:0032587 ruffle membrane(GO:0032587)
0.1 1.3 GO:0017119 Golgi transport complex(GO:0017119)
0.1 6.9 GO:0043202 lysosomal lumen(GO:0043202)
0.1 5.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 12.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 38.2 GO:0044431 Golgi apparatus part(GO:0044431)
0.0 3.4 GO:0035579 specific granule membrane(GO:0035579)
0.0 2.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.9 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 1.9 GO:0015030 Cajal body(GO:0015030)
0.0 1.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.8 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
37.9 37.9 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
12.8 38.4 GO:0031862 prostanoid receptor binding(GO:0031862)
12.6 278.2 GO:0045504 dynein heavy chain binding(GO:0045504)
12.2 12.2 GO:0005119 smoothened binding(GO:0005119)
8.3 33.2 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
7.1 92.5 GO:0032027 myosin light chain binding(GO:0032027)
5.6 50.2 GO:0008158 hedgehog receptor activity(GO:0008158)
5.2 15.6 GO:0005136 interleukin-4 receptor binding(GO:0005136)
5.2 31.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
4.9 136.8 GO:0017160 Ral GTPase binding(GO:0017160)
4.8 28.5 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
4.4 178.7 GO:0043015 gamma-tubulin binding(GO:0043015)
3.9 27.6 GO:0004127 cytidylate kinase activity(GO:0004127)
3.7 14.8 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
3.5 28.2 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
3.4 94.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
3.1 43.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
3.0 78.0 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
2.8 28.1 GO:0004565 beta-galactosidase activity(GO:0004565)
2.8 16.8 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
2.8 13.8 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
2.7 34.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
2.5 12.6 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
2.5 12.5 GO:0002046 opsin binding(GO:0002046)
2.5 32.5 GO:0034452 dynactin binding(GO:0034452)
2.5 57.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
2.5 22.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
2.4 16.9 GO:0061649 ubiquitinated histone binding(GO:0061649)
2.3 25.8 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
2.3 6.9 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
2.3 6.8 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
2.1 10.3 GO:0070568 guanylyltransferase activity(GO:0070568)
1.8 50.7 GO:0070840 dynein complex binding(GO:0070840)
1.7 136.3 GO:0003777 microtubule motor activity(GO:0003777)
1.7 31.0 GO:0004707 MAP kinase activity(GO:0004707)
1.6 93.8 GO:0030544 Hsp70 protein binding(GO:0030544)
1.5 5.9 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
1.5 26.5 GO:0070513 death domain binding(GO:0070513)
1.4 24.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.3 344.9 GO:0008017 microtubule binding(GO:0008017)
1.3 11.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
1.3 7.5 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
1.2 8.5 GO:0004673 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
1.2 62.4 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
1.2 33.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.1 30.4 GO:0005112 Notch binding(GO:0005112)
1.1 8.9 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.1 3.3 GO:0035514 DNA demethylase activity(GO:0035514)
1.1 60.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
1.0 39.5 GO:0030332 cyclin binding(GO:0030332)
0.9 40.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.9 14.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.8 25.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.8 2.5 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.8 29.9 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.8 34.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.8 2.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.7 2.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.7 28.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.7 47.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.7 77.3 GO:0051087 chaperone binding(GO:0051087)
0.7 3.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.7 19.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.7 2.0 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.6 7.0 GO:0015232 heme transporter activity(GO:0015232)
0.6 29.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.6 4.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.6 75.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.6 6.1 GO:0019826 oxygen sensor activity(GO:0019826)
0.5 9.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.5 13.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.5 5.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.5 15.5 GO:0030507 spectrin binding(GO:0030507)
0.5 18.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.5 2.3 GO:0004966 galanin receptor activity(GO:0004966)
0.5 4.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 8.1 GO:0035497 cAMP response element binding(GO:0035497)
0.4 31.6 GO:0015631 tubulin binding(GO:0015631)
0.4 408.8 GO:0005509 calcium ion binding(GO:0005509)
0.4 8.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 30.0 GO:0019887 protein kinase regulator activity(GO:0019887)
0.3 4.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.3 1.4 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.3 5.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.3 2.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.3 0.6 GO:0015235 cobalamin transporter activity(GO:0015235)
0.3 3.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 2.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.3 134.6 GO:0005525 GTP binding(GO:0005525)
0.3 4.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.3 4.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 1.6 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.3 27.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.3 6.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 1.9 GO:0048156 tau protein binding(GO:0048156)
0.2 14.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.2 9.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 7.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 1.0 GO:0016417 S-acyltransferase activity(GO:0016417)
0.2 114.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.2 5.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 6.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 12.2 GO:0016279 protein-lysine N-methyltransferase activity(GO:0016279)
0.1 31.2 GO:0005516 calmodulin binding(GO:0005516)
0.1 60.4 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 14.3 GO:0043130 ubiquitin binding(GO:0043130)
0.1 19.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 66.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 22.7 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 38.3 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.1 2.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 12.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 3.0 GO:0001972 retinoic acid binding(GO:0001972)
0.1 5.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.5 GO:0003774 motor activity(GO:0003774)
0.1 2.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 7.1 GO:0051082 unfolded protein binding(GO:0051082)
0.1 0.5 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 1.0 GO:0005537 mannose binding(GO:0005537)
0.1 1.0 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 0.6 GO:0004645 phosphorylase activity(GO:0004645)
0.0 766.8 GO:0003674 molecular_function(GO:0003674)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 51.0 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.6 29.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.6 24.9 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.5 35.9 PID_PLK1_PATHWAY PLK1 signaling events
0.5 39.1 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.4 43.3 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.4 19.4 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.3 5.9 PID_ALK2_PATHWAY ALK2 signaling events
0.3 24.0 PID_TNF_PATHWAY TNF receptor signaling pathway
0.3 17.8 PID_P53_REGULATION_PATHWAY p53 pathway
0.2 10.8 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.2 16.3 PID_NOTCH_PATHWAY Notch signaling pathway
0.2 6.1 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 30.7 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.1 4.7 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 2.0 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.5 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.1 8.1 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.1 7.3 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 7.1 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.1 2.5 PID_ARF6_PATHWAY Arf6 signaling events
0.1 4.4 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.3 PID_IL2_1PATHWAY IL2-mediated signaling events
0.1 16.7 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.1 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 2.2 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 4.1 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 3.6 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 1.9 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.2 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.6 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.7 PID_BMP_PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 58.9 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
1.8 66.6 REACTOME_KINESINS Genes involved in Kinesins
1.6 29.6 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
1.5 29.9 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
1.2 24.9 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
1.1 29.1 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
1.0 17.4 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
1.0 14.3 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.7 7.6 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.6 34.8 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.6 15.9 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.5 34.3 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.4 39.4 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.4 6.0 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3 8.6 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.3 9.5 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.3 6.8 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 8.1 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.2 8.5 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 1.6 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.2 3.4 REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.2 5.2 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.2 6.7 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 14.0 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 6.1 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 6.1 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 5.7 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 8.2 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 2.2 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 5.1 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 0.7 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 2.9 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.3 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.2 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 3.6 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 7.9 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 5.7 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 1.3 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.8 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 4.6 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.7 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 1.2 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 2.7 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.4 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes