Motif ID: RFX7_RFX4_RFX1

Z-value: 11.337

Transcription factors associated with RFX7_RFX4_RFX1:

Gene SymbolEntrez IDGene Name
RFX1 ENSG00000132005.4 RFX1
RFX4 ENSG00000111783.8 RFX4
RFX7 ENSG00000181827.10 RFX7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RFX7hg19_v2_chr15_-_56535464_56535521-0.462.5e-02Click!
RFX1hg19_v2_chr19_-_14117074_14117141-0.252.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of RFX7_RFX4_RFX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_55888186 195.079 ENST00000291934.3
TMEM190
transmembrane protein 190
chr1_-_109655355 105.649 ENST00000369945.3
C1orf194
chromosome 1 open reading frame 194
chr1_-_109655377 105.217 ENST00000369948.3
C1orf194
chromosome 1 open reading frame 194
chr1_-_161337662 101.218 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr10_+_23216944 83.831 ENST00000298032.5
ENST00000409983.3
ENST00000409049.3
ARMC3


armadillo repeat containing 3


chr9_-_138391692 83.734 ENST00000429260.2
C9orf116
chromosome 9 open reading frame 116
chr10_+_23217006 81.721 ENST00000376528.4
ENST00000447081.1
ARMC3

armadillo repeat containing 3

chr10_-_25305011 77.147 ENST00000331161.4
ENST00000376363.1
ENKUR

enkurin, TRPC channel interacting protein

chr16_+_80574854 76.088 ENST00000305904.6
ENST00000568035.1
DYNLRB2

dynein, light chain, roadblock-type 2

chr6_+_163148973 74.336 ENST00000366888.2
PACRG
PARK2 co-regulated
chr20_+_56725952 69.610 ENST00000371168.3
C20orf85
chromosome 20 open reading frame 85
chr22_-_23484246 67.944 ENST00000216036.4
RTDR1
rhabdoid tumor deletion region gene 1
chr21_-_43916433 67.928 ENST00000291536.3
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr22_+_23487513 66.916 ENST00000263116.2
ENST00000341989.4
RAB36

RAB36, member RAS oncogene family

chr1_+_36549676 65.869 ENST00000207457.3
TEKT2
tektin 2 (testicular)
chr1_+_85527987 64.779 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63


WD repeat domain 63


chr21_-_43916296 64.060 ENST00000398352.3
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr9_-_34381536 61.682 ENST00000379126.3
ENST00000379127.1
ENST00000379133.3
C9orf24


chromosome 9 open reading frame 24


chr9_-_34381511 61.037 ENST00000379124.1
C9orf24
chromosome 9 open reading frame 24
chr22_-_50970919 59.379 ENST00000329363.4
ENST00000437588.1
ODF3B

outer dense fiber of sperm tails 3B

chr6_+_32407619 58.354 ENST00000395388.2
ENST00000374982.5
HLA-DRA

major histocompatibility complex, class II, DR alpha

chr15_-_55790515 57.752 ENST00000448430.2
ENST00000457155.2
DYX1C1

dyslexia susceptibility 1 candidate 1

chr17_+_72270429 54.885 ENST00000311014.6
DNAI2
dynein, axonemal, intermediate chain 2
chr7_-_123174610 53.535 ENST00000324698.6
ENST00000434450.1
IQUB

IQ motif and ubiquitin domain containing

chr17_+_45908974 53.533 ENST00000269025.4
LRRC46
leucine rich repeat containing 46
chr8_+_94767072 50.779 ENST00000452276.1
ENST00000453321.3
ENST00000498673.1
ENST00000518319.1
TMEM67



transmembrane protein 67



chr6_+_116937636 47.828 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
RSPH4A


radial spoke head 4 homolog A (Chlamydomonas)


chr19_-_11545920 47.206 ENST00000356392.4
ENST00000591179.1
CCDC151

coiled-coil domain containing 151

chr19_-_50316517 47.063 ENST00000313777.4
ENST00000445575.2
FUZ

fuzzy planar cell polarity protein

chr17_+_72270380 46.103 ENST00000582036.1
ENST00000307504.5
DNAI2

dynein, axonemal, intermediate chain 2

chr1_-_36916066 46.083 ENST00000315643.9
OSCP1
organic solute carrier partner 1
chr5_-_137475071 45.347 ENST00000265191.2
NME5
NME/NM23 family member 5
chr17_+_17876127 45.225 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
LRRC48









leucine rich repeat containing 48









chr17_+_11501748 43.450 ENST00000262442.4
ENST00000579828.1
DNAH9

dynein, axonemal, heavy chain 9

chr12_+_111051832 42.531 ENST00000550703.2
ENST00000551590.1
TCTN1

tectonic family member 1

chr2_+_54558004 42.432 ENST00000405749.1
ENST00000398634.2
ENST00000447328.1
C2orf73


chromosome 2 open reading frame 73


chr19_-_50316423 42.160 ENST00000528094.1
ENST00000526575.1
FUZ

fuzzy planar cell polarity protein

chr12_+_111051902 42.056 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
TCTN1



tectonic family member 1



chr19_-_50316489 41.910 ENST00000533418.1
FUZ
fuzzy planar cell polarity protein
chr8_+_94767109 41.026 ENST00000409623.3
ENST00000453906.1
ENST00000521517.1
TMEM67


transmembrane protein 67


chr2_-_170550877 40.722 ENST00000447353.1
CCDC173
coiled-coil domain containing 173
chr10_-_82116505 39.919 ENST00000372202.1
ENST00000421924.2
ENST00000453477.1
DYDC1


DPY30 domain containing 1


chr11_+_71791693 39.412 ENST00000289488.2
ENST00000447974.1
LRTOMT

leucine rich transmembrane and O-methyltransferase domain containing

chr10_-_82116497 39.041 ENST00000372204.3
DYDC1
DPY30 domain containing 1
chr2_+_26624775 38.651 ENST00000288710.2
DRC1
dynein regulatory complex subunit 1 homolog (Chlamydomonas)
chr14_+_96858433 37.972 ENST00000267584.4
AK7
adenylate kinase 7
chr12_+_119772502 36.656 ENST00000536742.1
ENST00000327554.2
CCDC60

coiled-coil domain containing 60

chr1_-_169396666 36.323 ENST00000456107.1
ENST00000367805.3
CCDC181

coiled-coil domain containing 181

chrX_+_133371077 36.023 ENST00000517294.1
ENST00000370809.4
CCDC160

coiled-coil domain containing 160

chr11_+_71791803 35.522 ENST00000539271.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr1_-_169396646 34.930 ENST00000367806.3
CCDC181
coiled-coil domain containing 181
chrX_-_44202857 34.549 ENST00000420999.1
EFHC2
EF-hand domain (C-terminal) containing 2
chr1_-_36915880 34.094 ENST00000445843.3
OSCP1
organic solute carrier partner 1
chr17_+_42977122 33.794 ENST00000417826.2
ENST00000412523.2
ENST00000331733.4
CCDC103
FAM187A

coiled-coil domain containing 103
family with sequence similarity 187, member A

chr22_-_50970506 33.590 ENST00000428989.2
ENST00000403326.1
ODF3B

outer dense fiber of sperm tails 3B

chr1_+_111888890 33.190 ENST00000369738.4
PIFO
primary cilia formation
chr1_+_111889212 32.978 ENST00000369737.4
PIFO
primary cilia formation
chr16_-_67700594 32.970 ENST00000602644.1
ENST00000243878.4
ENKD1

enkurin domain containing 1

chr1_+_161068179 32.267 ENST00000368011.4
ENST00000392192.2
KLHDC9

kelch domain containing 9

chr2_+_29204161 31.836 ENST00000379558.4
ENST00000403861.2
FAM179A

family with sequence similarity 179, member A

chr22_+_45809560 31.782 ENST00000342894.3
ENST00000538017.1
RIBC2

RIB43A domain with coiled-coils 2

chr2_-_196933536 31.201 ENST00000312428.6
ENST00000410072.1
DNAH7

dynein, axonemal, heavy chain 7

chr11_+_71791359 30.939 ENST00000419228.1
ENST00000435085.1
ENST00000307198.7
ENST00000538413.1
LRTOMT



leucine rich transmembrane and O-methyltransferase domain containing



chr9_+_72435709 30.512 ENST00000377197.3
ENST00000527647.1
C9orf135

chromosome 9 open reading frame 135

chr1_-_36916011 30.356 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
OSCP1


organic solute carrier partner 1


chr3_+_63638339 30.328 ENST00000343837.3
ENST00000469440.1
SNTN

sentan, cilia apical structure protein

chr10_+_15001430 30.245 ENST00000407572.1
MEIG1
meiosis/spermiogenesis associated 1
chr3_-_19975665 30.175 ENST00000295824.9
ENST00000389256.4
EFHB

EF-hand domain family, member B

chr16_+_57406368 29.684 ENST00000006053.6
ENST00000563383.1
CX3CL1

chemokine (C-X3-C motif) ligand 1

chr11_+_61248583 29.660 ENST00000432063.2
ENST00000338608.2
PPP1R32

protein phosphatase 1, regulatory subunit 32

chr3_+_97483572 29.526 ENST00000335979.2
ENST00000394206.1
ARL6

ADP-ribosylation factor-like 6

chr4_-_177116772 29.242 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr9_+_34458771 28.362 ENST00000437363.1
ENST00000242317.4
DNAI1

dynein, axonemal, intermediate chain 1

chr3_+_97483366 28.308 ENST00000463745.1
ENST00000462412.1
ARL6

ADP-ribosylation factor-like 6

chr2_-_220110187 28.278 ENST00000295759.7
ENST00000392089.2
GLB1L

galactosidase, beta 1-like

chr2_-_220110111 28.234 ENST00000428427.1
ENST00000356283.3
ENST00000432839.1
ENST00000424620.1
GLB1L



galactosidase, beta 1-like



chr12_+_49297899 27.558 ENST00000552942.1
ENST00000320516.4
CCDC65

coiled-coil domain containing 65

chr19_+_5914213 27.136 ENST00000222125.5
ENST00000452990.2
ENST00000588865.1
CAPS


calcyphosine


chr11_+_86085778 26.471 ENST00000354755.1
ENST00000278487.3
ENST00000531271.1
ENST00000445632.2
CCDC81



coiled-coil domain containing 81



chr3_-_167098059 26.177 ENST00000392764.1
ENST00000474464.1
ENST00000392766.2
ENST00000485651.1
ZBBX



zinc finger, B-box domain containing



chr13_+_50589390 26.154 ENST00000360473.4
ENST00000312942.1
KCNRG

potassium channel regulator

chr1_+_217804661 25.909 ENST00000366933.4
SPATA17
spermatogenesis associated 17
chr12_-_113658892 25.814 ENST00000299732.2
ENST00000416617.2
IQCD

IQ motif containing D

chr10_-_82116467 25.343 ENST00000454362.1
DYDC1
DPY30 domain containing 1
chr1_-_60539405 24.914 ENST00000450089.2
C1orf87
chromosome 1 open reading frame 87
chr13_+_21141270 24.843 ENST00000319980.6
ENST00000537103.1
ENST00000389373.3
IFT88


intraflagellar transport 88 homolog (Chlamydomonas)


chr1_-_60539422 24.645 ENST00000371201.3
C1orf87
chromosome 1 open reading frame 87
chr10_+_82116529 24.454 ENST00000411538.1
ENST00000256039.2
DYDC2

DPY30 domain containing 2

chr13_+_21141208 24.271 ENST00000351808.5
IFT88
intraflagellar transport 88 homolog (Chlamydomonas)
chr6_+_52285131 23.674 ENST00000433625.2
EFHC1
EF-hand domain (C-terminal) containing 1
chr3_-_197676740 23.339 ENST00000452735.1
ENST00000453254.1
ENST00000455191.1
IQCG


IQ motif containing G


chr1_-_75139397 23.338 ENST00000326665.5
C1orf173
chromosome 1 open reading frame 173
chr12_-_71551868 23.172 ENST00000247829.3
TSPAN8
tetraspanin 8
chr5_-_110062349 23.088 ENST00000511883.2
ENST00000455884.2
TMEM232

transmembrane protein 232

chr11_-_47736896 22.970 ENST00000525123.1
ENST00000528244.1
ENST00000532595.1
ENST00000529154.1
ENST00000530969.1
AGBL2




ATP/GTP binding protein-like 2




chr22_-_50970566 22.936 ENST00000405135.1
ENST00000401779.1
ODF3B

outer dense fiber of sperm tails 3B

chr6_+_112408768 22.853 ENST00000368656.2
ENST00000604268.1
FAM229B

family with sequence similarity 229, member B

chr5_-_110062384 22.845 ENST00000429839.2
TMEM232
transmembrane protein 232
chr20_-_18447667 22.819 ENST00000262547.5
ENST00000329494.5
ENST00000357236.4
DZANK1


double zinc ribbon and ankyrin repeat domains 1


chr16_-_30773372 22.751 ENST00000545825.1
ENST00000541260.1
C16orf93

chromosome 16 open reading frame 93

chr11_-_8615507 22.693 ENST00000431279.2
ENST00000418597.1
STK33

serine/threonine kinase 33

chr6_-_33041378 22.577 ENST00000428995.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr2_+_61293021 22.532 ENST00000402291.1
KIAA1841
KIAA1841
chr11_+_113185251 22.514 ENST00000529221.1
TTC12
tetratricopeptide repeat domain 12
chr3_+_39149298 22.314 ENST00000440121.1
TTC21A
tetratricopeptide repeat domain 21A
chr15_+_71185148 22.229 ENST00000443425.2
ENST00000560755.1
LRRC49

leucine rich repeat containing 49

chr19_-_55791431 22.222 ENST00000593263.1
ENST00000376343.3
HSPBP1

HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1

chr15_+_71184931 22.163 ENST00000560369.1
ENST00000260382.5
LRRC49

leucine rich repeat containing 49

chr3_+_39149145 22.138 ENST00000301819.6
ENST00000431162.2
TTC21A

tetratricopeptide repeat domain 21A

chr10_+_106113515 22.137 ENST00000369704.3
ENST00000312902.5
CCDC147

coiled-coil domain containing 147

chr12_-_71551652 21.623 ENST00000546561.1
TSPAN8
tetraspanin 8
chr11_-_108422926 21.430 ENST00000428840.1
ENST00000526312.1
EXPH5

exophilin 5

chr2_+_106682135 20.816 ENST00000437659.1
C2orf40
chromosome 2 open reading frame 40
chr12_-_49582978 20.321 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr2_-_62081254 20.263 ENST00000405894.3
FAM161A
family with sequence similarity 161, member A
chr2_-_62081148 20.146 ENST00000404929.1
FAM161A
family with sequence similarity 161, member A
chr15_+_67547163 19.869 ENST00000335894.4
IQCH
IQ motif containing H
chr12_-_58329819 19.762 ENST00000551421.1
RP11-620J15.3
RP11-620J15.3
chr2_+_95537170 19.533 ENST00000295201.4
TEKT4
tektin 4
chr16_-_776431 19.516 ENST00000293889.6
CCDC78
coiled-coil domain containing 78
chr2_+_73612858 19.388 ENST00000409009.1
ENST00000264448.6
ENST00000377715.1
ALMS1


Alstrom syndrome 1


chr16_-_75590114 19.365 ENST00000568377.1
ENST00000565067.1
ENST00000258173.6
TMEM231


transmembrane protein 231


chr2_+_219536749 19.234 ENST00000295709.3
ENST00000392106.2
ENST00000392105.3
ENST00000455724.1
STK36



serine/threonine kinase 36



chr12_+_113587558 19.165 ENST00000335621.6
CCDC42B
coiled-coil domain containing 42B
chr2_-_63815860 19.034 ENST00000272321.7
ENST00000431065.1
WDPCP

WD repeat containing planar cell polarity effector

chr2_-_27851843 18.974 ENST00000324364.3
CCDC121
coiled-coil domain containing 121
chr3_+_93698974 18.894 ENST00000535334.1
ENST00000478400.1
ENST00000303097.7
ENST00000394222.3
ENST00000471138.1
ENST00000539730.1
ARL13B





ADP-ribosylation factor-like 13B





chr10_-_28287968 18.810 ENST00000305242.5
ARMC4
armadillo repeat containing 4
chr14_+_75536335 18.730 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
ZC2HC1C



zinc finger, C2HC-type containing 1C



chr15_+_74610894 18.695 ENST00000558821.1
ENST00000268082.4
CCDC33

coiled-coil domain containing 33

chr2_+_219537015 18.645 ENST00000440309.1
ENST00000424080.1
STK36

serine/threonine kinase 36

chr13_+_24153488 18.632 ENST00000382258.4
ENST00000382263.3
TNFRSF19

tumor necrosis factor receptor superfamily, member 19

chr4_-_2420335 18.360 ENST00000503000.1
ZFYVE28
zinc finger, FYVE domain containing 28
chr14_+_75536280 18.269 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr16_-_67450325 17.967 ENST00000348579.2
ZDHHC1
zinc finger, DHHC-type containing 1
chr5_+_121465207 17.862 ENST00000296600.4
ZNF474
zinc finger protein 474
chr11_+_537494 17.642 ENST00000270115.7
LRRC56
leucine rich repeat containing 56
chr19_-_55791563 17.522 ENST00000588971.1
ENST00000255631.5
ENST00000587551.1
HSPBP1


HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1


chr1_-_118727781 17.496 ENST00000336338.5
SPAG17
sperm associated antigen 17
chr2_-_207629997 17.331 ENST00000454776.2
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr15_+_81426588 17.279 ENST00000286732.4
C15orf26
chromosome 15 open reading frame 26
chr6_-_165723088 16.972 ENST00000230301.8
C6orf118
chromosome 6 open reading frame 118
chr15_-_56757329 16.924 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr14_+_105452094 16.914 ENST00000551606.1
ENST00000547315.1
C14orf79

chromosome 14 open reading frame 79

chrX_+_35937843 16.755 ENST00000297866.5
CXorf22
chromosome X open reading frame 22
chr11_+_124543694 16.514 ENST00000227135.2
ENST00000532692.1
SPA17

sperm autoantigenic protein 17

chr2_-_207630033 16.510 ENST00000449792.1
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr19_-_55791058 16.367 ENST00000587959.1
ENST00000585927.1
ENST00000587922.1
ENST00000585698.1
HSPBP1



HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1



chr6_+_52285046 16.306 ENST00000371068.5
EFHC1
EF-hand domain (C-terminal) containing 1
chr21_-_47738112 16.220 ENST00000417060.1
C21orf58
chromosome 21 open reading frame 58
chr7_+_158649242 16.203 ENST00000407559.3
WDR60
WD repeat domain 60
chr8_+_144798429 16.041 ENST00000338033.4
ENST00000395107.4
ENST00000395108.2
MAPK15


mitogen-activated protein kinase 15


chr1_+_118148556 15.968 ENST00000369448.3
FAM46C
family with sequence similarity 46, member C
chr19_+_55996565 15.783 ENST00000587400.1
NAT14
N-acetyltransferase 14 (GCN5-related, putative)
chr1_+_20512568 15.684 ENST00000375099.3
UBXN10
UBX domain protein 10
chr7_+_89874524 15.447 ENST00000497910.1
C7orf63
chromosome 7 open reading frame 63
chr6_-_43478239 15.268 ENST00000372441.1
LRRC73
leucine rich repeat containing 73
chr2_-_230579185 15.243 ENST00000341772.4
DNER
delta/notch-like EGF repeat containing
chr7_+_89874483 15.225 ENST00000389297.4
ENST00000316089.8
C7orf63

chromosome 7 open reading frame 63

chr2_+_170550944 15.217 ENST00000359744.3
ENST00000438838.1
ENST00000438710.1
ENST00000449906.1
ENST00000498202.2
ENST00000272797.4
PHOSPHO2



KLHL23

phosphatase, orphan 2



kelch-like family member 23

chr19_-_55791540 15.210 ENST00000433386.2
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr19_+_55996316 15.104 ENST00000205194.4
NAT14
N-acetyltransferase 14 (GCN5-related, putative)
chr2_+_219187871 15.059 ENST00000258362.3
PNKD
paroxysmal nonkinesigenic dyskinesia
chr6_+_151815143 14.928 ENST00000239374.7
ENST00000367290.5
CCDC170

coiled-coil domain containing 170

chr4_-_156298028 14.894 ENST00000433024.1
ENST00000379248.2
MAP9

microtubule-associated protein 9

chr11_+_113185292 14.836 ENST00000429951.1
ENST00000442859.1
ENST00000531164.1
ENST00000529850.1
ENST00000314756.3
ENST00000525965.1
TTC12





tetratricopeptide repeat domain 12





chr17_-_56296580 14.794 ENST00000313863.6
ENST00000546108.1
ENST00000337050.7
ENST00000393119.2
MKS1



Meckel syndrome, type 1



chr11_-_8615720 14.680 ENST00000358872.3
ENST00000454443.2
STK33

serine/threonine kinase 33

chr6_+_146920097 14.589 ENST00000397944.3
ENST00000522242.1
ADGB

androglobin

chr12_+_49297887 14.583 ENST00000266984.5
CCDC65
coiled-coil domain containing 65
chr11_-_8615488 14.543 ENST00000315204.1
ENST00000396672.1
ENST00000396673.1
STK33


serine/threonine kinase 33


chr6_-_159421198 14.454 ENST00000252655.1
ENST00000297262.3
ENST00000367069.2
RSPH3


radial spoke 3 homolog (Chlamydomonas)


chr12_+_122667658 14.341 ENST00000339777.4
ENST00000425921.1
LRRC43

leucine rich repeat containing 43

chr2_+_39103103 14.309 ENST00000340556.6
ENST00000410014.1
ENST00000409665.1
ENST00000409077.2
ENST00000409131.2
MORN2




MORN repeat containing 2




chr3_-_167371740 14.257 ENST00000466760.1
ENST00000479765.1
WDR49

WD repeat domain 49

chr4_+_15471489 14.242 ENST00000424120.1
ENST00000413206.1
ENST00000438599.2
ENST00000511544.1
ENST00000512702.1
ENST00000507954.1
ENST00000515124.1
ENST00000503292.1
ENST00000503658.1
CC2D2A








coiled-coil and C2 domain containing 2A








chr1_+_1109272 14.222 ENST00000379290.1
ENST00000379289.1
TTLL10

tubulin tyrosine ligase-like family, member 10

chr3_-_112565703 14.075 ENST00000488794.1
CD200R1L
CD200 receptor 1-like
chr6_+_146920116 13.869 ENST00000367493.3
ADGB
androglobin
chr4_-_156298087 13.817 ENST00000311277.4
MAP9
microtubule-associated protein 9
chr11_+_6260298 13.689 ENST00000379936.2
CNGA4
cyclic nucleotide gated channel alpha 4
chr6_-_159420780 13.353 ENST00000449822.1
RSPH3
radial spoke 3 homolog (Chlamydomonas)
chr7_+_138818490 12.894 ENST00000430935.1
ENST00000495038.1
ENST00000474035.2
ENST00000478836.2
ENST00000464848.1
ENST00000343187.4
TTC26





tetratricopeptide repeat domain 26





chr1_+_245133062 12.881 ENST00000366523.1
EFCAB2
EF-hand calcium binding domain 2
chr9_-_90589586 12.764 ENST00000325303.8
ENST00000375883.3
CDK20

cyclin-dependent kinase 20

chr14_+_74111578 12.623 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1






dynein, axonemal, light chain 1






chr2_+_26785409 12.578 ENST00000329615.3
ENST00000409392.1
C2orf70

chromosome 2 open reading frame 70

chr1_+_32674675 12.557 ENST00000409358.1
DCDC2B
doublecortin domain containing 2B
chr4_+_81256871 12.361 ENST00000358105.3
ENST00000508675.1
C4orf22

chromosome 4 open reading frame 22

chr3_-_47324079 12.180 ENST00000352910.4
KIF9
kinesin family member 9
chr4_-_156297949 12.135 ENST00000515654.1
MAP9
microtubule-associated protein 9
chr6_+_147091575 12.131 ENST00000326916.8
ENST00000470716.2
ENST00000367488.1
ADGB


androglobin


chr9_-_90589402 12.116 ENST00000375871.4
ENST00000605159.1
ENST00000336654.5
CDK20


cyclin-dependent kinase 20


chr16_+_3550924 12.009 ENST00000576634.1
ENST00000574369.1
ENST00000341633.5
ENST00000417763.2
ENST00000571025.1
CLUAP1




clusterin associated protein 1




chr21_-_35883541 11.840 ENST00000399284.1
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr11_-_85397167 11.829 ENST00000316398.3
CCDC89
coiled-coil domain containing 89
chr18_-_47792851 11.822 ENST00000398545.4
CCDC11
coiled-coil domain containing 11
chr16_+_19467772 11.821 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
TMC5


transmembrane channel-like 5


chr13_+_103046954 11.796 ENST00000606448.1
FGF14-AS2
FGF14 antisense RNA 2
chr3_+_158288942 11.796 ENST00000491767.1
ENST00000355893.5
MLF1

myeloid leukemia factor 1


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
32.8 131.1 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
16.3 65.2 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
14.9 59.8 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
14.4 86.5 GO:0036159 inner dynein arm assembly(GO:0036159)
14.1 98.8 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
11.5 241.8 GO:0036158 outer dynein arm assembly(GO:0036158)
9.6 28.7 GO:0050902 leukocyte adhesive activation(GO:0050902)
8.9 124.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
8.8 300.8 GO:0035082 axoneme assembly(GO:0035082)
7.9 110.6 GO:0003351 epithelial cilium movement(GO:0003351)
6.6 19.7 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
5.3 105.9 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
5.1 91.8 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
5.0 15.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
4.9 14.6 GO:0032203 telomere formation via telomerase(GO:0032203)
4.5 40.8 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
4.4 26.4 GO:0032185 regulation of embryonic cell shape(GO:0016476) septin cytoskeleton organization(GO:0032185) glomerular visceral epithelial cell migration(GO:0090521)
4.3 4.3 GO:0018307 enzyme active site formation(GO:0018307)
4.3 286.1 GO:0042073 intraciliary transport(GO:0042073)
3.6 14.2 GO:0018094 protein polyglycylation(GO:0018094)
3.5 10.4 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
3.3 16.7 GO:0022027 interkinetic nuclear migration(GO:0022027)
3.3 61.9 GO:0003341 cilium movement(GO:0003341)
3.1 9.4 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
3.0 14.8 GO:0061009 common bile duct development(GO:0061009)
2.9 20.0 GO:0098535 de novo centriole assembly(GO:0098535)
2.5 12.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
2.4 33.8 GO:0006108 malate metabolic process(GO:0006108)
2.2 38.0 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
2.2 35.2 GO:0070986 left/right axis specification(GO:0070986)
2.1 17.0 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
2.0 18.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
2.0 4.0 GO:0023021 termination of signal transduction(GO:0023021)
2.0 7.8 GO:2001178 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
1.9 5.6 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
1.6 3.3 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539)
1.5 4.6 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
1.3 162.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
1.2 3.7 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
1.2 20.8 GO:0070314 G1 to G0 transition(GO:0070314)
1.2 12.0 GO:0046477 glycosylceramide catabolic process(GO:0046477)
1.2 7.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
1.2 4.7 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
1.1 43.3 GO:0071801 regulation of podosome assembly(GO:0071801)
1.1 6.6 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
1.0 3.1 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
1.0 1.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
1.0 3.1 GO:1902214 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) regulation of interleukin-4-mediated signaling pathway(GO:1902214)
1.0 28.6 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
1.0 57.2 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
1.0 21.4 GO:0003334 keratinocyte development(GO:0003334)
1.0 19.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.9 11.4 GO:0044458 motile cilium assembly(GO:0044458)
0.9 1.9 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.9 3.5 GO:0061511 centriole elongation(GO:0061511)
0.8 2.5 GO:0031247 actin rod assembly(GO:0031247)
0.8 6.6 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.8 3.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.8 19.9 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.8 6.3 GO:0070092 negative regulation of glycogen biosynthetic process(GO:0045719) regulation of glucagon secretion(GO:0070092)
0.8 1.6 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.8 2.3 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.7 2.2 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.7 7.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.7 9.9 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.7 158.1 GO:0060271 cilium morphogenesis(GO:0060271)
0.7 2.0 GO:1902869 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) negative regulation of photoreceptor cell differentiation(GO:0046533) regulation of amacrine cell differentiation(GO:1902869)
0.6 1.3 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.6 2.5 GO:0003094 glomerular filtration(GO:0003094) renal filtration(GO:0097205)
0.6 8.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.6 3.8 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.6 10.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.6 3.7 GO:0008063 Toll signaling pathway(GO:0008063)
0.6 2.5 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.6 7.8 GO:0030321 transepithelial chloride transport(GO:0030321)
0.6 6.5 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.6 1.8 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.6 2.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.6 9.8 GO:0007220 Notch receptor processing(GO:0007220)
0.6 65.8 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.6 1.7 GO:2001160 histone H3-K79 methylation(GO:0034729) regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.5 37.7 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.5 186.0 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.5 1.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.5 3.8 GO:0030242 pexophagy(GO:0030242)
0.5 15.3 GO:0018345 protein palmitoylation(GO:0018345)
0.5 77.0 GO:0007286 spermatid development(GO:0007286)
0.5 8.1 GO:0045475 locomotor rhythm(GO:0045475)
0.5 37.0 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.5 0.9 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.4 2.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.4 5.3 GO:0032990 cell part morphogenesis(GO:0032990)
0.4 9.9 GO:0006012 galactose metabolic process(GO:0006012)
0.4 2.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.4 1.6 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.4 3.9 GO:1902116 negative regulation of organelle assembly(GO:1902116)
0.4 2.9 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.4 2.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.3 2.1 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.3 8.1 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.3 1.8 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.3 3.0 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.3 6.0 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.3 2.8 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.3 1.1 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.3 7.4 GO:0002021 response to dietary excess(GO:0002021)
0.3 2.1 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.3 53.1 GO:0007018 microtubule-based movement(GO:0007018)
0.3 1.6 GO:0048388 endosomal lumen acidification(GO:0048388)
0.3 1.3 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.3 1.5 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.3 1.0 GO:0043335 protein unfolding(GO:0043335)
0.2 3.5 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.2 1.7 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.2 4.4 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.2 21.2 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.2 6.9 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.2 5.4 GO:0019216 regulation of lipid metabolic process(GO:0019216)
0.2 36.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.2 2.0 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.2 1.7 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.2 6.0 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.2 0.9 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.2 1.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.2 1.7 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.2 27.0 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.2 0.8 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.2 1.0 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.2 1.0 GO:1904431 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.2 0.4 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.2 7.0 GO:0071625 vocalization behavior(GO:0071625)
0.2 1.7 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 0.9 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.2 0.9 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 1.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.2 1.0 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 11.4 GO:0032418 lysosome localization(GO:0032418)
0.2 0.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.2 1.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 1.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 2.4 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 1.8 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 4.7 GO:0010165 response to X-ray(GO:0010165)
0.1 3.4 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 1.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 1.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 2.8 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 12.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 3.7 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.1 4.9 GO:0042407 cristae formation(GO:0042407)
0.1 0.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 1.4 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 1.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 0.5 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.4 GO:0010836 base-excision repair, DNA ligation(GO:0006288) negative regulation of protein ADP-ribosylation(GO:0010836) regulation of single strand break repair(GO:1903516)
0.1 1.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 2.6 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.1 9.7 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 3.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 12.2 GO:0007608 sensory perception of smell(GO:0007608)
0.1 2.5 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.1 1.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 6.0 GO:0009060 aerobic respiration(GO:0009060)
0.1 2.8 GO:0006631 fatty acid metabolic process(GO:0006631)
0.1 8.4 GO:0001942 hair follicle development(GO:0001942)
0.1 2.0 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 0.4 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.3 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 2.3 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 4.8 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 0.4 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.8 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 40.3 GO:0031344 regulation of cell projection organization(GO:0031344)
0.1 1.0 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 4.3 GO:0051492 regulation of stress fiber assembly(GO:0051492)
0.0 0.3 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 2.0 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.3 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.0 0.5 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 1.5 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 1.1 GO:0015695 organic cation transport(GO:0015695)
0.0 1.0 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.2 GO:1903299 regulation of glucokinase activity(GO:0033131) regulation of hexokinase activity(GO:1903299)
0.0 1.6 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 1.5 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 1.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.4 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 1.8 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.7 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 2.4 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.4 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.2 GO:0015698 inorganic anion transport(GO:0015698)
0.0 0.5 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
39.0 195.1 GO:0002079 inner acrosomal membrane(GO:0002079)
19.8 218.1 GO:0036157 outer dynein arm(GO:0036157)
15.9 47.8 GO:0001534 radial spoke(GO:0001534)
13.5 94.6 GO:0002177 manchette(GO:0002177)
12.3 234.5 GO:0036038 MKS complex(GO:0036038)
11.6 57.8 GO:0005879 axonemal microtubule(GO:0005879)
10.7 128.9 GO:0072687 meiotic spindle(GO:0072687)
6.7 20.1 GO:1990716 axonemal central apparatus(GO:1990716)
6.2 130.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
5.6 5.6 GO:0030990 intraciliary transport particle(GO:0030990)
5.4 16.2 GO:0031021 interphase microtubule organizing center(GO:0031021)
5.0 144.8 GO:0030992 intraciliary transport particle B(GO:0030992)
4.4 44.5 GO:0030991 intraciliary transport particle A(GO:0030991)
4.1 74.3 GO:0097225 sperm midpiece(GO:0097225)
4.1 41.3 GO:0044447 axoneme part(GO:0044447)
4.1 85.5 GO:0042613 MHC class II protein complex(GO:0042613)
4.0 20.0 GO:0098536 deuterosome(GO:0098536)
3.9 15.7 GO:0016939 kinesin II complex(GO:0016939)
3.7 29.7 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
3.5 297.9 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
2.6 69.8 GO:0097228 sperm principal piece(GO:0097228)
2.4 134.2 GO:0036126 sperm flagellum(GO:0036126)
2.4 21.2 GO:0034464 BBSome(GO:0034464)
2.2 37.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
2.0 110.5 GO:0009925 basal plasma membrane(GO:0009925)
1.8 76.3 GO:0030286 dynein complex(GO:0030286)
1.4 57.2 GO:0031514 motile cilium(GO:0031514)
1.0 61.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
1.0 72.2 GO:0036064 ciliary basal body(GO:0036064)
0.9 6.5 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.8 22.9 GO:0097546 ciliary base(GO:0097546)
0.8 6.8 GO:1990111 spermatoproteasome complex(GO:1990111)
0.7 2.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.7 41.9 GO:0005871 kinesin complex(GO:0005871)
0.6 10.8 GO:0000242 pericentriolar material(GO:0000242)
0.6 17.0 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.6 4.9 GO:0061617 MICOS complex(GO:0061617)
0.6 14.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.6 150.5 GO:0005929 cilium(GO:0005929)
0.5 6.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.5 2.5 GO:0070695 FHF complex(GO:0070695)
0.5 2.3 GO:0005869 dynactin complex(GO:0005869)
0.4 2.2 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.4 1.7 GO:0055087 Ski complex(GO:0055087)
0.4 2.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.4 14.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.4 0.7 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.3 1.0 GO:0031933 telomeric heterochromatin(GO:0031933)
0.3 1.5 GO:1990769 proximal neuron projection(GO:1990769)
0.3 3.8 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.3 2.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.3 3.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.3 6.0 GO:1902911 protein kinase complex(GO:1902911)
0.3 17.7 GO:0005814 centriole(GO:0005814)
0.2 1.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.2 1.7 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 2.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 1.9 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 2.5 GO:0070938 contractile ring(GO:0070938)
0.2 1.7 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 1.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 2.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 1.4 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.2 7.7 GO:0030496 midbody(GO:0030496)
0.2 4.0 GO:0042599 lamellar body(GO:0042599)
0.2 7.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.6 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 6.6 GO:0035861 site of double-strand break(GO:0035861)
0.1 64.3 GO:0005813 centrosome(GO:0005813)
0.1 1.3 GO:0070761 PCAF complex(GO:0000125) pre-snoRNP complex(GO:0070761)
0.1 1.8 GO:0005902 microvillus(GO:0005902)
0.1 22.5 GO:0031901 early endosome membrane(GO:0031901)
0.1 1.3 GO:0051233 spindle midzone(GO:0051233)
0.1 8.2 GO:0031519 PcG protein complex(GO:0031519)
0.1 16.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 4.8 GO:0016235 aggresome(GO:0016235)
0.1 2.9 GO:0005901 caveola(GO:0005901)
0.1 5.8 GO:0097610 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.1 7.8 GO:0034707 chloride channel complex(GO:0034707)
0.1 2.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 2.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 1.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 2.0 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.3 GO:0032021 NELF complex(GO:0032021)
0.1 2.3 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.1 7.8 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 3.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0005638 lamin filament(GO:0005638)
0.0 5.1 GO:0005643 nuclear pore(GO:0005643)
0.0 6.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.1 GO:0005771 multivesicular body(GO:0005771)
0.0 2.0 GO:1902555 endoribonuclease complex(GO:1902555)
0.0 1.1 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 38.1 GO:0009986 cell surface(GO:0009986)
0.0 1.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 5.2 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 3.1 GO:0043209 myelin sheath(GO:0043209)
0.0 5.7 GO:0005769 early endosome(GO:0005769)
0.0 3.4 GO:0016605 PML body(GO:0016605)
0.0 21.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 3.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.7 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 1.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 3.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.3 GO:0031672 A band(GO:0031672)
0.0 1.4 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.9 GO:0031252 cell leading edge(GO:0031252)
0.0 0.4 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
11.8 105.9 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
10.4 228.6 GO:0045504 dynein heavy chain binding(GO:0045504)
8.3 24.9 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
6.8 47.5 GO:0004127 cytidylate kinase activity(GO:0004127)
5.7 56.5 GO:0004565 beta-galactosidase activity(GO:0004565)
5.6 78.6 GO:0032395 MHC class II receptor activity(GO:0032395)
5.4 130.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
5.4 149.9 GO:0045505 dynein intermediate chain binding(GO:0045505)
5.0 15.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
4.8 33.8 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
3.7 91.8 GO:0031005 filamin binding(GO:0031005)
3.3 10.0 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
3.3 9.9 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
3.1 74.8 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
2.8 147.2 GO:0048487 beta-tubulin binding(GO:0048487)
2.7 16.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
2.4 196.6 GO:0043621 protein self-association(GO:0043621)
2.4 14.2 GO:0070735 protein-glycine ligase activity(GO:0070735)
1.9 9.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
1.8 9.0 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
1.5 4.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
1.2 11.8 GO:0031433 telethonin binding(GO:0031433)
1.1 6.8 GO:0003998 acylphosphatase activity(GO:0003998)
1.1 5.6 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
1.1 6.5 GO:0039552 RIG-I binding(GO:0039552)
1.1 3.2 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
1.0 3.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
1.0 17.0 GO:0043014 alpha-tubulin binding(GO:0043014)
1.0 7.0 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.9 5.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.8 3.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.7 4.3 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.7 29.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.7 52.6 GO:0003777 microtubule motor activity(GO:0003777)
0.7 16.0 GO:0004707 MAP kinase activity(GO:0004707)
0.6 28.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.6 26.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.6 2.8 GO:0004905 type I interferon receptor activity(GO:0004905)
0.5 7.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.5 2.5 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.5 7.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.5 15.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.5 18.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.5 2.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.5 1.4 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.4 1.7 GO:0004948 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.4 2.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.4 19.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.4 1.6 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.4 2.0 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.4 1.5 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.4 6.0 GO:0031996 thioesterase binding(GO:0031996)
0.4 14.6 GO:0070034 telomerase RNA binding(GO:0070034)
0.4 9.8 GO:0005112 Notch binding(GO:0005112)
0.4 2.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.4 1.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.4 2.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.3 1.7 GO:0008422 glucosylceramidase activity(GO:0004348) beta-glucosidase activity(GO:0008422)
0.3 6.5 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.3 69.1 GO:0017124 SH3 domain binding(GO:0017124)
0.3 12.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 17.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.3 82.7 GO:0008017 microtubule binding(GO:0008017)
0.3 3.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 0.9 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3 153.6 GO:0005525 GTP binding(GO:0005525)
0.3 7.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.3 8.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3 5.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.3 6.9 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.3 1.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.3 1.0 GO:0015616 DNA translocase activity(GO:0015616)
0.2 10.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.2 14.8 GO:0005096 GTPase activator activity(GO:0005096)
0.2 2.0 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 5.6 GO:0046965 retinoid X receptor binding(GO:0046965)
0.2 1.4 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2 8.3 GO:0030332 cyclin binding(GO:0030332)
0.2 7.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 4.9 GO:0016805 dipeptidase activity(GO:0016805)
0.2 4.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 1.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 10.0 GO:0030552 cAMP binding(GO:0030552)
0.2 3.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 2.8 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.2 2.8 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 1.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 2.1 GO:0019871 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.2 19.9 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.2 2.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.4 GO:0048156 tau protein binding(GO:0048156)
0.1 1.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 2.6 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 5.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 1.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 3.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.9 GO:0030274 LIM domain binding(GO:0030274)
0.1 9.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 21.2 GO:0005178 integrin binding(GO:0005178)
0.1 1.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.7 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136)
0.1 12.0 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 18.1 GO:0005516 calmodulin binding(GO:0005516)
0.1 0.3 GO:0070538 oleic acid binding(GO:0070538)
0.1 1.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 18.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 0.3 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 2.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 1.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 4.8 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.1 6.9 GO:0004497 monooxygenase activity(GO:0004497)
0.1 49.3 GO:0005509 calcium ion binding(GO:0005509)
0.1 5.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 1.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 1.2 GO:0003774 motor activity(GO:0003774)
0.0 5.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 2.3 GO:0050699 WW domain binding(GO:0050699)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.0 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 20.0 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 17.1 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 1.1 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 1.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 2.3 GO:0051287 NAD binding(GO:0051287)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 3.0 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.1 GO:0019239 deaminase activity(GO:0019239)
0.0 0.9 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 1.4 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 92.6 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
1.0 51.9 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.7 6.6 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.4 28.6 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.4 3.8 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.4 5.7 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3 19.2 PID_PLK1_PATHWAY PLK1 signaling events
0.2 4.6 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 5.6 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.2 14.4 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 1.5 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 4.0 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.1 30.7 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.1 5.8 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.1 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 6.0 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 3.9 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 2.1 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.8 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 4.9 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.6 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.8 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 2.1 PID_P73PATHWAY p73 transcription factor network
0.0 1.0 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.8 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 0.3 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 41.5 REACTOME_KINESINS Genes involved in Kinesins
1.1 28.6 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
1.0 22.6 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.5 9.0 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.4 25.4 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.4 34.3 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.3 3.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.3 7.1 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.3 16.8 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.3 9.7 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 0.4 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.2 3.7 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.2 4.5 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.1 4.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 4.8 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.5 REACTOME_REGULATION_OF_INSULIN_SECRETION Genes involved in Regulation of Insulin Secretion
0.1 2.1 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 5.3 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.1 2.0 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 0.9 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 2.8 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.2 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 4.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 5.4 REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 1.9 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.1 0.1 REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.1 1.0 REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 1.5 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 2.2 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 2.5 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.1 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.2 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.8 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 2.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 2.9 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS Genes involved in Synthesis of bile acids and bile salts