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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_+_17272608	2.488	ENST00000421459.2	VIM	vimentin
chr10_+_17270214	2.006	ENST00000544301.1	VIM	vimentin
chr11_-_58345569	1.921	ENST00000528954.1 ENST00000528489.1	LPXN	leupaxin
chr22_+_31488433	1.850	ENST00000455608.1	SMTN	smoothelin
chr5_-_39270725	1.713	ENST00000512138.1 ENST00000512982.1 ENST00000540520.1	FYB	FYN binding protein
chrX_-_106960285	1.573	ENST00000503515.1 ENST00000372397.2	TSC22D3	TSC22 domain family, member 3
chr1_+_152486950	1.212	ENST00000368790.3	CRCT1	cysteine-rich C-terminal 1
chr1_+_45205498	1.194	ENST00000372218.4	KIF2C	kinesin family member 2C
chr1_+_45205478	1.158	ENST00000452259.1 ENST00000372224.4	KIF2C	kinesin family member 2C
chr4_+_88896819	1.068	ENST00000237623.7 ENST00000395080.3 ENST00000508233.1 ENST00000360804.4	SPP1	secreted phosphoprotein 1
chr5_-_39203093	1.059	ENST00000515010.1	FYB	FYN binding protein
chr2_+_33359687	1.047	ENST00000402934.1 ENST00000404525.1 ENST00000407925.1	LTBP1	latent transforming growth factor beta binding protein 1
chr2_+_33359646	1.000	ENST00000390003.4 ENST00000418533.2	LTBP1	latent transforming growth factor beta binding protein 1
chr1_-_94147385	0.975	ENST00000260502.6	BCAR3	breast cancer anti-estrogen resistance 3
chr6_+_86159821	0.971	ENST00000369651.3	NT5E	5'-nucleotidase, ecto (CD73)
chr6_+_45296048	0.953	ENST00000465038.2 ENST00000352853.5 ENST00000541979.1 ENST00000371438.1	RUNX2	runt-related transcription factor 2
chr22_+_40297079	0.949	ENST00000344138.4 ENST00000543252.1	GRAP2	GRB2-related adaptor protein 2
chr10_+_5566916	0.944	ENST00000315238.1	CALML3	calmodulin-like 3
chr22_+_40297105	0.929	ENST00000540310.1	GRAP2	GRB2-related adaptor protein 2
chr14_+_85996471	0.880	ENST00000330753.4	FLRT2	fibronectin leucine rich transmembrane protein 2
chr3_-_33686925	0.819	ENST00000485378.2 ENST00000313350.6 ENST00000487200.1	CLASP2	cytoplasmic linker associated protein 2
chr11_-_66725837	0.817	ENST00000393958.2 ENST00000393960.1 ENST00000524491.1 ENST00000355677.3	PC	pyruvate carboxylase
chr1_+_110453462	0.814	ENST00000488198.1	CSF1	colony stimulating factor 1 (macrophage)
chr1_+_23695680	0.812	ENST00000454117.1 ENST00000335648.3 ENST00000518821.1 ENST00000437367.2	C1orf213	chromosome 1 open reading frame 213
chr2_-_55646957	0.796	ENST00000263630.8	CCDC88A	coiled-coil domain containing 88A
chr6_+_45296391	0.783	ENST00000371436.6 ENST00000576263.1	RUNX2	runt-related transcription factor 2
chr1_+_209859510	0.783	ENST00000367028.2 ENST00000261465.1	HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1
chr11_-_128457446	0.715	ENST00000392668.4	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr2_-_55647057	0.711	ENST00000436346.1	CCDC88A	coiled-coil domain containing 88A
chr14_-_35183755	0.697	ENST00000555765.1	CFL2	cofilin 2 (muscle)
chr1_-_179112173	0.677	ENST00000408940.3 ENST00000504405.1	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase
chr10_+_112404132	0.652	ENST00000369519.3	RBM20	RNA binding motif protein 20
chr12_-_4754339	0.625	ENST00000228850.1	AKAP3	A kinase (PRKA) anchor protein 3
chr12_-_71031185	0.620	ENST00000548122.1 ENST00000551525.1 ENST00000550358.1	PTPRB	protein tyrosine phosphatase, receptor type, B
chr2_-_119605253	0.619	ENST00000295206.6	EN1	engrailed homeobox 1
chr1_+_39546988	0.617	ENST00000484793.1	MACF1	microtubule-actin crosslinking factor 1
chr15_-_64665911	0.614	ENST00000606793.1 ENST00000561349.1 ENST00000560278.1	CTD-2116N17.1	Uncharacterized protein
chr7_+_18535346	0.609	ENST00000405010.3 ENST00000406451.4 ENST00000428307.2	HDAC9	histone deacetylase 9
chr8_+_31497271	0.607	ENST00000520407.1	NRG1	neuregulin 1
chr20_-_54967187	0.604	ENST00000422322.1 ENST00000371356.2 ENST00000451915.1 ENST00000347343.2 ENST00000395911.1 ENST00000395907.1 ENST00000441357.1 ENST00000456249.1 ENST00000420474.1 ENST00000395909.4 ENST00000395914.1 ENST00000312783.6 ENST00000395915.3 ENST00000395913.3	AURKA	aurora kinase A
chr6_+_74405501	0.600	ENST00000437994.2 ENST00000422508.2	CD109	CD109 molecule
chr9_-_93925369	0.593	ENST00000457976.1	RP11-305L7.3	RP11-305L7.3
chr1_+_110453608	0.592	ENST00000369801.1	CSF1	colony stimulating factor 1 (macrophage)
chr4_-_152147579	0.588	ENST00000304527.4 ENST00000455740.1 ENST00000424281.1 ENST00000409598.4	SH3D19	SH3 domain containing 19
chr13_-_103053946	0.587	ENST00000376131.4	FGF14	fibroblast growth factor 14
chr19_-_44285401	0.578	ENST00000262888.3	KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr5_+_131409476	0.558	ENST00000296871.2	CSF2	colony stimulating factor 2 (granulocyte-macrophage)
chr17_-_74533963	0.531	ENST00000293230.5	CYGB	cytoglobin
chrX_+_68048803	0.530	ENST00000204961.4	EFNB1	ephrin-B1
chr21_-_36421401	0.521	ENST00000486278.2	RUNX1	runt-related transcription factor 1
chr9_-_95166841	0.514	ENST00000262551.4	OGN	osteoglycin
chr1_-_24469602	0.513	ENST00000270800.1	IL22RA1	interleukin 22 receptor, alpha 1
chr9_-_95166884	0.512	ENST00000375561.5	OGN	osteoglycin
chr3_-_189840223	0.510	ENST00000427335.2	LEPREL1	leprecan-like 1
chr11_-_19262486	0.509	ENST00000250024.4	E2F8	E2F transcription factor 8
chr20_+_30028322	0.509	ENST00000376309.3	DEFB123	defensin, beta 123
chr10_-_14372870	0.503	ENST00000357447.2	FRMD4A	FERM domain containing 4A
chr2_-_50574856	0.500	ENST00000342183.5	NRXN1	neurexin 1
chr15_+_67418047	0.498	ENST00000540846.2	SMAD3	SMAD family member 3
chr14_-_35183886	0.497	ENST00000298159.6	CFL2	cofilin 2 (muscle)
chr11_-_102826434	0.494	ENST00000340273.4 ENST00000260302.3	MMP13	matrix metallopeptidase 13 (collagenase 3)
chr11_+_35198243	0.491	ENST00000528455.1	CD44	CD44 molecule (Indian blood group)
chr21_+_31768348	0.490	ENST00000355459.2	KRTAP13-1	keratin associated protein 13-1
chr1_-_149889382	0.487	ENST00000369145.1 ENST00000369146.3	SV2A	synaptic vesicle glycoprotein 2A
chr8_+_27168988	0.478	ENST00000397501.1 ENST00000338238.4 ENST00000544172.1	PTK2B	protein tyrosine kinase 2 beta
chr11_+_124735282	0.473	ENST00000397801.1	ROBO3	roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr13_-_46756351	0.472	ENST00000323076.2	LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr14_-_85996332	0.471	ENST00000380722.1	RP11-497E19.1	RP11-497E19.1
chrX_+_37639302	0.470	ENST00000545017.1 ENST00000536160.1	CYBB	cytochrome b-245, beta polypeptide
chr12_-_53012343	0.459	ENST00000305748.3	KRT73	keratin 73
chr7_+_45067265	0.457	ENST00000474617.1	CCM2	cerebral cavernous malformation 2
chr4_+_71091786	0.455	ENST00000317987.5	FDCSP	follicular dendritic cell secreted protein
chr6_+_30029008	0.435	ENST00000332435.5 ENST00000376782.2 ENST00000359374.4 ENST00000376785.2	ZNRD1	zinc ribbon domain containing 1
chr10_+_101419187	0.434	ENST00000370489.4	ENTPD7	ectonucleoside triphosphate diphosphohydrolase 7
chr11_+_35198118	0.432	ENST00000525211.1 ENST00000526000.1 ENST00000279452.6 ENST00000527889.1	CD44	CD44 molecule (Indian blood group)
chr1_+_110453514	0.426	ENST00000369802.3 ENST00000420111.2	CSF1	colony stimulating factor 1 (macrophage)
chr21_-_40033618	0.423	ENST00000417133.2 ENST00000398910.1 ENST00000442448.1	ERG	v-ets avian erythroblastosis virus E26 oncogene homolog
chr8_+_27182862	0.419	ENST00000521164.1 ENST00000346049.5	PTK2B	protein tyrosine kinase 2 beta
chr6_-_52109335	0.419	ENST00000336123.4	IL17F	interleukin 17F
chr4_-_57976544	0.416	ENST00000295666.4 ENST00000537922.1	IGFBP7	insulin-like growth factor binding protein 7
chr15_+_63335899	0.416	ENST00000561266.1	TPM1	tropomyosin 1 (alpha)
chr8_+_27183033	0.413	ENST00000420218.2	PTK2B	protein tyrosine kinase 2 beta
chr3_+_141105235	0.412	ENST00000503809.1	ZBTB38	zinc finger and BTB domain containing 38
chr2_+_90077680	0.403	ENST00000390270.2	IGKV3D-20	immunoglobulin kappa variable 3D-20
chr17_-_29648761	0.401	ENST00000247270.3 ENST00000462804.2	EVI2A	ecotropic viral integration site 2A
chr1_-_25291475	0.396	ENST00000338888.3 ENST00000399916.1	RUNX3	runt-related transcription factor 3
chrX_+_47441712	0.393	ENST00000218388.4 ENST00000377018.2 ENST00000456754.2 ENST00000377017.1 ENST00000441738.1	TIMP1	TIMP metallopeptidase inhibitor 1
chr19_+_41257084	0.393	ENST00000601393.1	SNRPA	small nuclear ribonucleoprotein polypeptide A
chr3_+_156799587	0.389	ENST00000469196.1	RP11-6F2.5	RP11-6F2.5
chr11_-_66103867	0.387	ENST00000424433.2	RIN1	Ras and Rab interactor 1
chr1_+_66999799	0.387	ENST00000371035.3 ENST00000371036.3 ENST00000371037.4	SGIP1	SH3-domain GRB2-like (endophilin) interacting protein 1
chr1_-_168513229	0.386	ENST00000367819.2	XCL2	chemokine (C motif) ligand 2
chr7_-_148580563	0.372	ENST00000476773.1	EZH2	enhancer of zeste homolog 2 (Drosophila)
chr4_-_57524061	0.370	ENST00000508121.1	HOPX	HOP homeobox
chr12_-_71031220	0.364	ENST00000334414.6	PTPRB	protein tyrosine phosphatase, receptor type, B
chr19_-_49496557	0.361	ENST00000323798.3 ENST00000541188.1 ENST00000544287.1 ENST00000540532.1 ENST00000263276.6	GYS1	glycogen synthase 1 (muscle)
chr10_-_13276329	0.354	ENST00000378681.3 ENST00000463405.2	UCMA	upper zone of growth plate and cartilage matrix associated
chrX_-_70838306	0.351	ENST00000373691.4 ENST00000373693.3	CXCR3	chemokine (C-X-C motif) receptor 3
chr5_+_135496675	0.351	ENST00000507637.1	SMAD5	SMAD family member 5
chr2_+_169659121	0.350	ENST00000397206.2 ENST00000397209.2 ENST00000421711.2	NOSTRIN	nitric oxide synthase trafficking
chr19_-_14785698	0.349	ENST00000344373.4 ENST00000595472.1	EMR3	egf-like module containing, mucin-like, hormone receptor-like 3
chr2_+_169658928	0.348	ENST00000317647.7 ENST00000445023.2	NOSTRIN	nitric oxide synthase trafficking
chr11_-_1643368	0.346	ENST00000399682.1	KRTAP5-4	keratin associated protein 5-4
chr19_-_14785622	0.344	ENST00000443157.2	EMR3	egf-like module containing, mucin-like, hormone receptor-like 3
chr11_+_60995849	0.339	ENST00000537932.1	PGA4	pepsinogen 4, group I (pepsinogen A)
chr12_+_79439405	0.336	ENST00000552744.1	SYT1	synaptotagmin I
chrX_-_15872914	0.334	ENST00000380291.1 ENST00000545766.1 ENST00000421527.2 ENST00000329235.2	AP1S2	adaptor-related protein complex 1, sigma 2 subunit
chr9_-_35103105	0.330	ENST00000452248.2 ENST00000356493.5	STOML2	stomatin (EPB72)-like 2
chr3_-_99569821	0.326	ENST00000487087.1	FILIP1L	filamin A interacting protein 1-like
chr19_-_14785674	0.323	ENST00000253673.5	EMR3	egf-like module containing, mucin-like, hormone receptor-like 3
chr1_-_173174681	0.321	ENST00000367718.1	TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr17_-_41623075	0.319	ENST00000545089.1	ETV4	ets variant 4
chr2_+_37571717	0.313	ENST00000338415.3 ENST00000404976.1	QPCT	glutaminyl-peptide cyclotransferase
chr17_-_73840415	0.313	ENST00000592386.1 ENST00000412096.2 ENST00000586147.1	UNC13D	unc-13 homolog D (C. elegans)
chr5_+_54398463	0.311	ENST00000274306.6	GZMA	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr20_+_36405665	0.310	ENST00000373469.1	CTNNBL1	catenin, beta like 1
chr14_+_85996507	0.307	ENST00000554746.1	FLRT2	fibronectin leucine rich transmembrane protein 2
chr2_+_37571845	0.305	ENST00000537448.1	QPCT	glutaminyl-peptide cyclotransferase
chr21_+_35552978	0.304	ENST00000428914.2 ENST00000609062.1 ENST00000609947.1	LINC00310	long intergenic non-protein coding RNA 310
chr1_+_110453203	0.299	ENST00000357302.4 ENST00000344188.5 ENST00000329608.6	CSF1	colony stimulating factor 1 (macrophage)
chr6_-_42418999	0.296	ENST00000340840.2 ENST00000354325.2	TRERF1	transcriptional regulating factor 1
chr3_+_121902511	0.295	ENST00000490131.1	CASR	calcium-sensing receptor
chr2_+_228678550	0.291	ENST00000409189.3 ENST00000358813.4	CCL20	chemokine (C-C motif) ligand 20
chr19_+_41882598	0.287	ENST00000447302.2 ENST00000544232.1 ENST00000542945.1 ENST00000540732.1	TMEM91 CTC-435M10.3	transmembrane protein 91 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; Uncharacterized protein
chr18_-_35145728	0.287	ENST00000361795.5 ENST00000603232.1	CELF4	CUGBP, Elav-like family member 4
chr3_+_189507523	0.284	ENST00000437221.1 ENST00000392463.2 ENST00000392461.3 ENST00000449992.1 ENST00000456148.1	TP63	tumor protein p63
chr19_-_14048804	0.281	ENST00000254320.3 ENST00000586075.1	PODNL1	podocan-like 1
chr19_-_14049184	0.279	ENST00000339560.5	PODNL1	podocan-like 1
chr11_+_61015594	0.278	ENST00000451616.2	PGA5	pepsinogen 5, group I (pepsinogen A)
chr10_+_25463951	0.277	ENST00000376351.3	GPR158	G protein-coupled receptor 158
chr6_-_34524049	0.275	ENST00000374037.3	SPDEF	SAM pointed domain containing ETS transcription factor
chr1_-_114414316	0.275	ENST00000528414.1 ENST00000538253.1 ENST00000460620.1 ENST00000420377.2 ENST00000525799.1 ENST00000359785.5	PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr1_-_157522180	0.274	ENST00000356953.4 ENST00000368188.2 ENST00000368190.3 ENST00000368189.3	FCRL5	Fc receptor-like 5
chrX_+_37639264	0.270	ENST00000378588.4	CYBB	cytochrome b-245, beta polypeptide
chr6_-_34524093	0.267	ENST00000544425.1	SPDEF	SAM pointed domain containing ETS transcription factor
chr2_+_182850551	0.267	ENST00000452904.1 ENST00000409137.3 ENST00000280295.3	PPP1R1C	protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr14_-_70655684	0.265	ENST00000356921.2 ENST00000381269.2 ENST00000357887.3	SLC8A3	solute carrier family 8 (sodium/calcium exchanger), member 3
chr12_-_51717948	0.261	ENST00000267012.4	BIN2	bridging integrator 2
chr3_-_71179988	0.261	ENST00000491238.1	FOXP1	forkhead box P1
chr8_-_60031762	0.260	ENST00000361421.1	TOX	thymocyte selection-associated high mobility group box
chr17_-_41623009	0.260	ENST00000393664.2	ETV4	ets variant 4
chr3_-_147124547	0.260	ENST00000491672.1 ENST00000383075.3	ZIC4	Zic family member 4
chr12_-_51717875	0.259	ENST00000604560.1	BIN2	bridging integrator 2
chr12_-_51717922	0.258	ENST00000452142.2	BIN2	bridging integrator 2
chr2_-_105030466	0.255	ENST00000449772.1	AC068535.3	AC068535.3
chr3_-_98241760	0.254	ENST00000507874.1 ENST00000502299.1 ENST00000508659.1 ENST00000510545.1 ENST00000511667.1 ENST00000394185.2 ENST00000394181.2 ENST00000508902.1 ENST00000341181.6 ENST00000437922.1 ENST00000394180.2	CLDND1	claudin domain containing 1
chr15_+_73976545	0.254	ENST00000318443.5 ENST00000537340.2 ENST00000318424.5	CD276	CD276 molecule
chr11_-_66104237	0.253	ENST00000530056.1	RIN1	Ras and Rab interactor 1
chr13_-_62001982	0.252	ENST00000409186.1	PCDH20	protocadherin 20
chr19_-_51220176	0.252	ENST00000359082.3 ENST00000293441.1	SHANK1	SH3 and multiple ankyrin repeat domains 1
chr1_+_50569575	0.252	ENST00000371827.1	ELAVL4	ELAV like neuron-specific RNA binding protein 4
chr11_-_2323089	0.245	ENST00000456145.2	C11orf21	chromosome 11 open reading frame 21
chr1_-_150978953	0.243	ENST00000493834.2	FAM63A	family with sequence similarity 63, member A
chr7_+_102389434	0.239	ENST00000409231.3 ENST00000418198.1	FAM185A	family with sequence similarity 185, member A
chr6_-_114664180	0.239	ENST00000312719.5	HS3ST5	heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr10_-_29811456	0.238	ENST00000535393.1	SVIL	supervillin
chr11_-_35287243	0.237	ENST00000464522.2	SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr10_+_89420706	0.236	ENST00000427144.2	PAPSS2	3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr14_+_22508822	0.233	ENST00000390448.3	TRAV20	T cell receptor alpha variable 20
chr1_-_175161890	0.233	ENST00000545251.2 ENST00000423313.1	KIAA0040	KIAA0040
chr3_+_136676851	0.232	ENST00000309741.5	IL20RB	interleukin 20 receptor beta
chr1_+_230193521	0.225	ENST00000543760.1	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr7_-_87104963	0.225	ENST00000359206.3 ENST00000358400.3 ENST00000265723.4	ABCB4	ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr1_-_182641367	0.224	ENST00000508450.1	RGS8	regulator of G-protein signaling 8
chr3_-_71179699	0.224	ENST00000497355.1	FOXP1	forkhead box P1
chr13_-_38172863	0.223	ENST00000541481.1 ENST00000379743.4 ENST00000379742.4 ENST00000379749.4 ENST00000541179.1 ENST00000379747.4	POSTN	periostin, osteoblast specific factor
chr2_+_202937972	0.222	ENST00000541917.1 ENST00000295844.3	AC079354.1	uncharacterized protein KIAA2012
chr12_+_75874984	0.221	ENST00000550491.1	GLIPR1	GLI pathogenesis-related 1
chr16_+_30075463	0.220	ENST00000562168.1 ENST00000569545.1	ALDOA	aldolase A, fructose-bisphosphate
chr1_-_150979333	0.219	ENST00000312210.5	FAM63A	family with sequence similarity 63, member A
chr1_-_153348067	0.216	ENST00000368737.3	S100A12	S100 calcium binding protein A12
chr3_-_33686743	0.215	ENST00000333778.6 ENST00000539981.1	CLASP2	cytoplasmic linker associated protein 2
chr1_+_111772314	0.214	ENST00000466741.1 ENST00000477185.2	CHI3L2	chitinase 3-like 2
chr3_+_136676707	0.212	ENST00000329582.4	IL20RB	interleukin 20 receptor beta
chr8_-_134072593	0.212	ENST00000427060.2	SLA	Src-like-adaptor
chr6_+_116692102	0.210	ENST00000359564.2	DSE	dermatan sulfate epimerase
chr14_+_97263641	0.209	ENST00000216639.3	VRK1	vaccinia related kinase 1
chr7_-_91764108	0.207	ENST00000450723.1	CYP51A1	cytochrome P450, family 51, subfamily A, polypeptide 1
chr8_+_21899898	0.206	ENST00000518533.1 ENST00000359441.3	FGF17	fibroblast growth factor 17
chr5_+_131993856	0.204	ENST00000304506.3	IL13	interleukin 13
chr20_+_43343476	0.203	ENST00000372868.2	WISP2	WNT1 inducible signaling pathway protein 2
chr6_+_160327974	0.203	ENST00000252660.4	MAS1	MAS1 oncogene
chr11_-_66103932	0.202	ENST00000311320.4	RIN1	Ras and Rab interactor 1
chr1_+_111772435	0.202	ENST00000524472.1	CHI3L2	chitinase 3-like 2
chr17_+_75447326	0.200	ENST00000591088.1	SEPT9	septin 9
chr3_+_51575596	0.200	ENST00000409535.2	RAD54L2	RAD54-like 2 (S. cerevisiae)
chr13_+_28527647	0.199	ENST00000567234.1	LINC00543	long intergenic non-protein coding RNA 543
chr19_-_15590306	0.198	ENST00000292609.4	PGLYRP2	peptidoglycan recognition protein 2
chr2_+_202316392	0.197	ENST00000194530.3 ENST00000392249.2	STRADB	STE20-related kinase adaptor beta
chr9_+_118916082	0.196	ENST00000328252.3	PAPPA	pregnancy-associated plasma protein A, pappalysin 1
chr17_-_48227877	0.195	ENST00000316878.6	PPP1R9B	protein phosphatase 1, regulatory subunit 9B
chr13_-_28674693	0.194	ENST00000537084.1 ENST00000241453.7 ENST00000380982.4	FLT3	fms-related tyrosine kinase 3
chr1_-_12677714	0.194	ENST00000376223.2	DHRS3	dehydrogenase/reductase (SDR family) member 3
chr20_+_43992094	0.192	ENST00000453003.1	SYS1	SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr3_+_50284321	0.190	ENST00000451956.1	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr3_+_132843652	0.190	ENST00000508711.1	TMEM108	transmembrane protein 108
chr11_+_60739249	0.189	ENST00000542157.1 ENST00000433107.2 ENST00000452451.2 ENST00000352009.5	CD6	CD6 molecule
chr15_+_68582544	0.188	ENST00000566008.1	FEM1B	fem-1 homolog b (C. elegans)
chr3_+_189507432	0.187	ENST00000354600.5	TP63	tumor protein p63
chr6_+_27925019	0.184	ENST00000244623.1	OR2B6	olfactory receptor, family 2, subfamily B, member 6

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.1	GO:1902228	mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.4	1.5	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.4	4.5	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.4	1.1	GO:2000866	positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.3	1.3	GO:0010752	regulation of cGMP-mediated signaling(GO:0010752)
0.3	0.8	GO:0019072	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2	1.0	GO:0046086	adenosine biosynthetic process(GO:0046086)
0.2	1.9	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.2	2.4	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2	2.2	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2	2.1	GO:0002051	osteoblast fate commitment(GO:0002051)
0.2	0.6	GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.2	0.6	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.2	1.2	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.2	1.6	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2	0.5	GO:0032877	positive regulation of DNA endoreduplication(GO:0032877)
0.2	0.5	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.2	0.6	GO:0061743	motor learning(GO:0061743)
0.1	0.7	GO:1904844	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1	0.4	GO:0036333	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1	0.9	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1	0.3	GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1	0.6	GO:0045918	negative regulation of cytolysis(GO:0045918)
0.1	0.3	GO:1901860	positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1	0.3	GO:0002728	negative regulation of natural killer cell cytokine production(GO:0002728)
0.1	0.8	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.1	0.4	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1	0.4	GO:0001808	negative regulation of type IV hypersensitivity(GO:0001808)
0.1	0.6	GO:0072675	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1	0.5	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.1	0.3	GO:0033140	negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1	0.3	GO:0045360	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1	0.5	GO:0032625	interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1	0.3	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1	0.7	GO:0030578	PML body organization(GO:0030578)
0.1	0.5	GO:2000490	negative regulation of hepatic stellate cell activation(GO:2000490)
0.1	0.6	GO:0021842	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1	0.7	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1	0.3	GO:0050894	determination of affect(GO:0050894)
0.1	0.2	GO:1901899	positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1	0.2	GO:0060557	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1	1.0	GO:0090091	positive regulation of extracellular matrix disassembly(GO:0090091)
0.1	0.3	GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1	0.2	GO:1903413	cellular response to mycotoxin(GO:0036146) glycoside transport(GO:1901656) cellular response to bile acid(GO:1903413)
0.1	1.2	GO:0030043	actin filament fragmentation(GO:0030043)
0.1	0.4	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.1	0.2	GO:0033861	negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.1	0.2	GO:0032824	natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.1	0.2	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.1	2.7	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.1	0.2	GO:0001545	primary ovarian follicle growth(GO:0001545)
0.1	0.6	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.1	0.4	GO:0051414	response to cortisol(GO:0051414)
0.1	0.5	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1	0.5	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.1	0.2	GO:0000103	sulfate assimilation(GO:0000103)
0.1	0.2	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.1	0.5	GO:0097116	gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1	0.2	GO:2000053	regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1	0.5	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
0.1	0.2	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
0.1	0.4	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
0.1	0.3	GO:0051549	positive regulation of keratinocyte migration(GO:0051549)
0.0	0.1	GO:2000502	negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0	0.9	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.0	0.4	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.0	0.7	GO:0046541	saliva secretion(GO:0046541)
0.0	0.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.2	GO:0097106	postsynaptic density organization(GO:0097106)
0.0	0.2	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.6	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.2	GO:1990523	bone regeneration(GO:1990523)
0.0	0.2	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.0	0.1	GO:0019442	tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0	0.4	GO:0010454	negative regulation of cell fate commitment(GO:0010454)
0.0	0.1	GO:0030185	nitric oxide transport(GO:0030185) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0	0.8	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
0.0	0.2	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0	0.2	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.8	GO:0097320	membrane tubulation(GO:0097320)
0.0	0.2	GO:0071104	response to interleukin-9(GO:0071104)
0.0	0.1	GO:0070676	intralumenal vesicle formation(GO:0070676)
0.0	0.3	GO:1990034	calcium ion export from cell(GO:1990034)
0.0	0.1	GO:0035964	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.3	GO:0072513	semicircular canal morphogenesis(GO:0048752) positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0	0.4	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.4	GO:0010668	ectodermal cell differentiation(GO:0010668)
0.0	0.5	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.0	0.9	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.1	GO:1901072	glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.4	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0	0.2	GO:0070836	caveola assembly(GO:0070836)
0.0	0.5	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.0	0.1	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.5	GO:0043320	natural killer cell degranulation(GO:0043320)
0.0	0.2	GO:0043987	histone H3-S10 phosphorylation(GO:0043987) Golgi disassembly(GO:0090166)
0.0	0.3	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.2	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	0.3	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	2.7	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0	0.2	GO:0035726	common myeloid progenitor cell proliferation(GO:0035726)
0.0	0.2	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.1	GO:0007566	embryo implantation(GO:0007566)
0.0	0.1	GO:0007499	ectoderm and mesoderm interaction(GO:0007499)
0.0	0.1	GO:0032581	ER-dependent peroxisome organization(GO:0032581)
0.0	0.4	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.0	0.2	GO:0003383	apical constriction(GO:0003383)
0.0	0.1	GO:0043313	regulation of neutrophil degranulation(GO:0043313)
0.0	0.1	GO:0046684	response to pyrethroid(GO:0046684)
0.0	0.1	GO:0050902	leukocyte adhesive activation(GO:0050902)
0.0	0.4	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.0	0.5	GO:0003417	growth plate cartilage development(GO:0003417)
0.0	0.5	GO:0001771	immunological synapse formation(GO:0001771)
0.0	0.1	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.1	GO:0038018	Wnt receptor catabolic process(GO:0038018)
0.0	0.1	GO:0048295	positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0	0.2	GO:2000252	negative regulation of feeding behavior(GO:2000252)
0.0	0.3	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.2	GO:1904869	regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0	0.2	GO:0038166	angiotensin-activated signaling pathway(GO:0038166)
0.0	0.4	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
0.0	0.2	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.4	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	0.5	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.3	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.3	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0	0.2	GO:1904936	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0	0.2	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	0.4	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.0	0.0	GO:0070173	regulation of enamel mineralization(GO:0070173)
0.0	0.6	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.0	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0	0.4	GO:2001044	regulation of integrin-mediated signaling pathway(GO:2001044)
0.0	0.1	GO:0035019	somatic stem cell population maintenance(GO:0035019)
0.0	0.1	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.0	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.2	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.6	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.0	0.2	GO:0032354	response to follicle-stimulating hormone(GO:0032354)
0.0	0.5	GO:0001755	neural crest cell migration(GO:0001755)
0.0	0.2	GO:0002097	tRNA wobble base modification(GO:0002097)
0.0	0.2	GO:0006751	glutathione catabolic process(GO:0006751)
0.0	0.6	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.1	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0	0.0	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0	0.2	GO:0007625	grooming behavior(GO:0007625)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.1	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.2	0.6	GO:0001674	female germ cell nucleus(GO:0001674)
0.1	0.4	GO:0034676	integrin alpha6-beta4 complex(GO:0034676)
0.1	0.9	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1	1.6	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	2.2	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.1	1.0	GO:0005828	kinetochore microtubule(GO:0005828)
0.1	0.3	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1	0.5	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.1	0.6	GO:0035686	sperm fibrous sheath(GO:0035686)
0.1	0.6	GO:0097486	multivesicular body lumen(GO:0097486)
0.1	1.9	GO:0035371	microtubule plus-end(GO:0035371)
0.0	3.4	GO:0002102	podosome(GO:0002102)
0.0	0.7	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.2	GO:0000333	telomerase catalytic core complex(GO:0000333)
0.0	0.6	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.1	GO:0097059	CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.0	5.4	GO:0005882	intermediate filament(GO:0005882)
0.0	0.1	GO:0031084	BLOC-2 complex(GO:0031084)
0.0	0.1	GO:0000126	transcription factor TFIIIB complex(GO:0000126)
0.0	0.1	GO:0032279	asymmetric synapse(GO:0032279)
0.0	0.4	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.8	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.4	GO:0045120	pronucleus(GO:0045120)
0.0	0.5	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.4	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.4	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.8	GO:0030673	axolemma(GO:0030673)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.2	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.2	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.0	0.6	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.4	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.2	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.0	0.6	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.2	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.3	GO:0031105	septin complex(GO:0031105)
0.0	1.2	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.3	GO:0000974	Prp19 complex(GO:0000974)
0.0	0.1	GO:0035976	AP1 complex(GO:0035976)
0.0	0.2	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	2.5	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:1990907	beta-catenin-TCF complex(GO:1990907)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	4.5	GO:1990254	keratin filament binding(GO:1990254)
0.4	1.3	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.4	2.0	GO:0050436	microfibril binding(GO:0050436)
0.3	2.1	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.3	0.8	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2	2.4	GO:0019237	centromeric DNA binding(GO:0019237)
0.2	0.6	GO:0016603	glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.2	1.6	GO:0043426	MRF binding(GO:0043426)
0.2	1.0	GO:0042015	interleukin-20 binding(GO:0042015)
0.1	0.5	GO:0047888	fatty acid peroxidase activity(GO:0047888)
0.1	0.6	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	1.8	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.3	GO:0008955	peptidoglycan glycosyltransferase activity(GO:0008955)
0.1	0.5	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.1	0.3	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.1	0.8	GO:0035174	histone serine kinase activity(GO:0035174)
0.1	0.5	GO:0042835	BRE binding(GO:0042835)
0.1	0.3	GO:0031877	somatostatin receptor binding(GO:0031877)
0.1	0.8	GO:0004075	biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.1	0.6	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.1	0.2	GO:0004781	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1	1.5	GO:0043422	protein kinase B binding(GO:0043422)
0.1	0.5	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.1	0.2	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1	0.2	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
0.1	0.3	GO:0030348	syntaxin-3 binding(GO:0030348)
0.1	0.2	GO:0003839	gamma-glutamylcyclotransferase activity(GO:0003839)
0.0	0.2	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.0	1.0	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.2	GO:0090554	phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0	0.2	GO:0046538	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0	0.2	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0	1.0	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.4	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0	0.7	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	1.5	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.4	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.3	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0	0.2	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.1	GO:0036361	racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0	0.4	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.3	GO:1901612	cardiolipin binding(GO:1901612)
0.0	0.2	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.2	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.0	0.4	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.6	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.4	GO:0004568	chitinase activity(GO:0004568)
0.0	0.4	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.5	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	1.4	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0	2.7	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0001026	TFIIIB-type transcription factor activity(GO:0001026)
0.0	0.2	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.8	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.9	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.2	GO:0070728	leucine binding(GO:0070728)
0.0	0.1	GO:0030395	lactose binding(GO:0030395)
0.0	0.1	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
0.0	0.6	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.1	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0	0.4	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	2.3	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.3	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.2	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
0.0	0.6	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.1	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.4	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	1.1	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.0	GO:0052810	1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.6	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0030884	lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0	0.1	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.2	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0036310	annealing helicase activity(GO:0036310)
0.0	0.8	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.2	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.4	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.4	GO:0008301	DNA binding, bending(GO:0008301)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	7.4	PID_AURORA_B_PATHWAY	Aurora B signaling
0.1	3.1	SA_MMP_CYTOKINE_CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	1.9	PID_TCR_JNK_PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	2.2	PID_AVB3_OPN_PATHWAY	Osteopontin-mediated events
0.0	1.7	NABA_PROTEOGLYCANS	Genes encoding proteoglycans
0.0	1.9	PID_FGF_PATHWAY	FGF signaling pathway
0.0	2.6	PID_TCR_PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	1.2	SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	2.6	PID_HIF1_TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.4	PID_ALK2_PATHWAY	ALK2 signaling events
0.0	0.8	PID_RAS_PATHWAY	Regulation of Ras family activation
0.0	0.1	ST_INTERFERON_GAMMA_PATHWAY	Interferon gamma pathway.
0.0	0.6	PID_GLYPICAN_1PATHWAY	Glypican 1 network
0.0	0.2	ST_IL_13_PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.6	PID_GMCSF_PATHWAY	GMCSF-mediated signaling events
0.0	0.1	PID_IL12_STAT4_PATHWAY	IL12 signaling mediated by STAT4
0.0	0.5	PID_EPHRINB_REV_PATHWAY	Ephrin B reverse signaling
0.0	0.3	PID_ECADHERIN_KERATINOCYTE_PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.5	PID_UPA_UPAR_PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	1.0	PID_CDC42_REG_PATHWAY	Regulation of CDC42 activity
0.0	0.2	SA_B_CELL_RECEPTOR_COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.5	PID_P38_ALPHA_BETA_PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.5	SIG_CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.2	PID_S1P_S1P4_PATHWAY	S1P4 pathway
0.0	0.7	PID_RAC1_PATHWAY	RAC1 signaling pathway
0.0	0.4	PID_INSULIN_GLUCOSE_PATHWAY	Insulin-mediated glucose transport
0.0	0.6	PID_HDAC_CLASSII_PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.4	PID_INTEGRIN_CS_PATHWAY	Integrin family cell surface interactions
0.0	0.4	PID_CXCR3_PATHWAY	CXCR3-mediated signaling events
0.0	0.8	PID_LKB1_PATHWAY	LKB1 signaling events
0.0	0.4	PID_IL6_7_PATHWAY	IL6-mediated signaling events
0.0	0.2	PID_SYNDECAN_3_PATHWAY	Syndecan-3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.6	REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	4.1	REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	1.0	REACTOME_PURINE_CATABOLISM	Genes involved in Purine catabolism
0.1	2.4	REACTOME_KINESINS	Genes involved in Kinesins
0.1	0.9	REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	0.9	REACTOME_KERATAN_SULFATE_DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	1.7	REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.7	REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.2	REACTOME_ENDOGENOUS_STEROLS	Genes involved in Endogenous sterols
0.0	1.0	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	1.2	REACTOME_SIGNALING_BY_ROBO_RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.6	REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.7	REACTOME_ENOS_ACTIVATION_AND_REGULATION	Genes involved in eNOS activation and regulation
0.0	0.3	REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.8	REACTOME_STEROID_HORMONES	Genes involved in Steroid hormones
0.0	0.3	REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.4	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.2	REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.4	REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.5	REACTOME_BETA_DEFENSINS	Genes involved in Beta defensins
0.0	0.4	REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.5	REACTOME_SIGNALING_BY_NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME_P2Y_RECEPTORS	Genes involved in P2Y receptors
0.0	0.1	REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.1	REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.4	REACTOME_IL_RECEPTOR_SHC_SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.7	REACTOME_GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.2	REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway

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