Motif ID: RXRG

Z-value: 1.642


Transcription factors associated with RXRG:

Gene SymbolEntrez IDGene Name
RXRG ENSG00000143171.8 RXRG

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RXRGhg19_v2_chr1_-_165414414_165414433-0.154.8e-01Click!


Activity profile for motif RXRG.

activity profile for motif RXRG


Sorted Z-values histogram for motif RXRG

Sorted Z-values for motif RXRG



Network of associatons between targets according to the STRING database.



First level regulatory network of RXRG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_51504852 5.096 ENST00000391806.2
ENST00000347619.4
ENST00000291726.7
ENST00000320838.5
KLK8



kallikrein-related peptidase 8



chr10_+_88718397 4.920 ENST00000372017.3
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr10_+_88718314 4.530 ENST00000348795.4
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr12_-_58131931 4.430 ENST00000547588.1
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr2_+_234104079 4.390 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr18_-_21242774 3.736 ENST00000322980.9
ANKRD29
ankyrin repeat domain 29
chr12_-_57634475 3.544 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr1_-_154946825 3.531 ENST00000368453.4
ENST00000368450.1
ENST00000366442.2
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr3_-_50340996 3.427 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1





hyaluronoglucosaminidase 1





chr17_+_39969183 2.989 ENST00000321562.4
FKBP10
FK506 binding protein 10, 65 kDa
chr1_-_153521597 2.964 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr18_-_21242833 2.963 ENST00000586087.1
ENST00000592179.1
ANKRD29

ankyrin repeat domain 29

chr7_+_2671663 2.923 ENST00000407643.1
TTYH3
tweety family member 3
chr16_-_85784557 2.888 ENST00000602675.1
C16orf74
chromosome 16 open reading frame 74
chr5_+_150591678 2.879 ENST00000523466.1
GM2A
GM2 ganglioside activator
chr22_+_31489344 2.834 ENST00000404574.1
SMTN
smoothelin
chr16_-_85784634 2.693 ENST00000284245.4
ENST00000602914.1
C16orf74

chromosome 16 open reading frame 74

chr6_+_43737939 2.690 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr17_+_7211280 2.591 ENST00000419711.2
ENST00000571955.1
ENST00000573714.1
EIF5A


eukaryotic translation initiation factor 5A


chr1_-_6479963 2.589 ENST00000377836.4
ENST00000487437.1
ENST00000489730.1
ENST00000377834.4
HES2



hes family bHLH transcription factor 2



chr12_-_51785182 2.564 ENST00000356317.3
ENST00000603188.1
ENST00000604847.1
ENST00000604506.1
GALNT6



UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)



chr17_+_39975455 2.550 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr17_+_40811283 2.547 ENST00000251412.7
TUBG2
tubulin, gamma 2
chr17_+_39975544 2.526 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr11_+_450255 2.463 ENST00000308020.5
PTDSS2
phosphatidylserine synthase 2
chr19_-_1174226 2.458 ENST00000587024.1
ENST00000361757.3
SBNO2

strawberry notch homolog 2 (Drosophila)

chr12_-_54813229 2.429 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_-_6420737 2.407 ENST00000541130.1
ENST00000377845.3
ACOT7

acyl-CoA thioesterase 7

chr19_+_926000 2.384 ENST00000263620.3
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr9_-_110251836 2.380 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr20_+_42295745 2.375 ENST00000396863.4
ENST00000217026.4
MYBL2

v-myb avian myeloblastosis viral oncogene homolog-like 2

chr19_-_46148820 2.332 ENST00000587152.1
EML2
echinoderm microtubule associated protein like 2
chr1_-_153521714 2.299 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr2_+_27008865 2.243 ENST00000335756.4
ENST00000233505.8
CENPA

centromere protein A

chr7_+_143079000 2.242 ENST00000392910.2
ZYX
zyxin
chr2_-_208031542 2.233 ENST00000423015.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr19_+_676385 2.219 ENST00000166139.4
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr7_+_116166331 2.218 ENST00000393468.1
ENST00000393467.1
CAV1

caveolin 1, caveolae protein, 22kDa

chr7_+_116165754 2.211 ENST00000405348.1
CAV1
caveolin 1, caveolae protein, 22kDa
chrX_+_135229600 2.160 ENST00000370690.3
FHL1
four and a half LIM domains 1
chr7_-_107643674 2.154 ENST00000222399.6
LAMB1
laminin, beta 1
chr17_+_3627185 2.127 ENST00000325418.4
GSG2
germ cell associated 2 (haspin)
chr22_+_38035459 2.116 ENST00000357436.4
SH3BP1
SH3-domain binding protein 1
chr15_-_75017711 2.095 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
CYP1A1





cytochrome P450, family 1, subfamily A, polypeptide 1





chr15_-_81616446 2.090 ENST00000302824.6
STARD5
StAR-related lipid transfer (START) domain containing 5
chr7_+_143078652 2.072 ENST00000354434.4
ENST00000449423.2
ZYX

zyxin

chr1_-_113498943 2.069 ENST00000369626.3
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr11_-_119599794 2.056 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr1_-_113498616 2.049 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1


solute carrier family 16 (monocarboxylate transporter), member 1


chr14_+_75745477 2.030 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS




FBJ murine osteosarcoma viral oncogene homolog




chr5_-_131562935 2.015 ENST00000379104.2
ENST00000379100.2
ENST00000428369.1
P4HA2


prolyl 4-hydroxylase, alpha polypeptide II


chr16_+_30194916 2.012 ENST00000570045.1
ENST00000565497.1
ENST00000570244.1
CORO1A


coronin, actin binding protein, 1A


chr17_-_39211463 1.999 ENST00000542910.1
ENST00000398477.1
KRTAP2-2

keratin associated protein 2-2

chr17_-_40575535 1.986 ENST00000357037.5
PTRF
polymerase I and transcript release factor
chr1_+_230202936 1.971 ENST00000366672.4
GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chrX_+_135229731 1.935 ENST00000420362.1
FHL1
four and a half LIM domains 1
chr18_+_56530794 1.928 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
ZNF532


zinc finger protein 532


chrX_+_135229559 1.927 ENST00000394155.2
FHL1
four and a half LIM domains 1
chr11_-_59436453 1.898 ENST00000300146.9
PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr12_-_52585765 1.881 ENST00000313234.5
ENST00000394815.2
KRT80

keratin 80

chr17_+_7210898 1.848 ENST00000572815.1
EIF5A
eukaryotic translation initiation factor 5A
chrX_-_49042778 1.846 ENST00000538114.1
ENST00000376310.3
ENST00000376317.3
ENST00000417014.1
PRICKLE3



prickle homolog 3 (Drosophila)



chr20_-_56285595 1.842 ENST00000395816.3
ENST00000347215.4
PMEPA1

prostate transmembrane protein, androgen induced 1

chr15_+_41523417 1.775 ENST00000560397.1
CHP1
calcineurin-like EF-hand protein 1
chr1_+_153750622 1.774 ENST00000532853.1
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr6_+_32121908 1.727 ENST00000375143.2
ENST00000424499.1
PPT2

palmitoyl-protein thioesterase 2

chr6_+_32121789 1.707 ENST00000437001.2
ENST00000375137.2
PPT2

palmitoyl-protein thioesterase 2

chr8_+_26371763 1.691 ENST00000521913.1
DPYSL2
dihydropyrimidinase-like 2
chr8_+_22423219 1.686 ENST00000523965.1
ENST00000521554.1
SORBS3

sorbin and SH3 domain containing 3

chrX_+_153686614 1.684 ENST00000369682.3
PLXNA3
plexin A3
chr17_+_7905912 1.660 ENST00000254854.4
GUCY2D
guanylate cyclase 2D, membrane (retina-specific)
chr17_+_36584662 1.655 ENST00000431231.2
ENST00000437668.3
ARHGAP23

Rho GTPase activating protein 23

chr1_+_26606608 1.642 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr15_+_67458357 1.636 ENST00000537194.2
SMAD3
SMAD family member 3
chr9_-_35103105 1.634 ENST00000452248.2
ENST00000356493.5
STOML2

stomatin (EPB72)-like 2

chr5_-_132112907 1.598 ENST00000458488.2
SEPT8
septin 8
chr21_-_45196326 1.598 ENST00000291568.5
CSTB
cystatin B (stefin B)
chr19_+_6361795 1.593 ENST00000596149.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr17_-_27278445 1.587 ENST00000268756.3
ENST00000584685.1
PHF12

PHD finger protein 12

chr5_-_149682447 1.586 ENST00000328668.7
ARSI
arylsulfatase family, member I
chr1_-_150693318 1.581 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMAD1




HORMA domain containing 1




chr5_-_132112921 1.562 ENST00000378721.4
ENST00000378701.1
SEPT8

septin 8

chr19_-_51143075 1.536 ENST00000600079.1
ENST00000593901.1
SYT3

synaptotagmin III

chr10_+_54074033 1.532 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr19_-_43708378 1.516 ENST00000599746.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr17_+_47074758 1.513 ENST00000290341.3
IGF2BP1
insulin-like growth factor 2 mRNA binding protein 1
chr20_-_56284816 1.510 ENST00000395819.3
ENST00000341744.3
PMEPA1

prostate transmembrane protein, androgen induced 1

chr19_-_52227221 1.491 ENST00000222115.1
ENST00000540069.2
HAS1

hyaluronan synthase 1

chr7_-_44229022 1.460 ENST00000403799.3
GCK
glucokinase (hexokinase 4)
chr9_+_116037922 1.454 ENST00000374198.4
PRPF4
pre-mRNA processing factor 4
chr17_-_39968406 1.443 ENST00000393928.1
LEPREL4
leprecan-like 4
chr21_-_47648665 1.422 ENST00000450351.1
ENST00000522411.1
ENST00000356396.4
ENST00000397728.3
ENST00000457828.2
LSS




lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)




chr2_+_113816685 1.420 ENST00000393200.2
IL36RN
interleukin 36 receptor antagonist
chr19_+_6361841 1.418 ENST00000596605.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr6_+_43738444 1.412 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
VEGFA








vascular endothelial growth factor A








chr11_+_12308447 1.406 ENST00000256186.2
MICALCL
MICAL C-terminal like
chr13_+_114321463 1.404 ENST00000335678.6
GRK1
G protein-coupled receptor kinase 1
chr12_-_48152611 1.395 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr19_-_50143452 1.386 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chrX_+_48911090 1.385 ENST00000597275.1
CCDC120
coiled-coil domain containing 120
chr13_-_103046837 1.383 ENST00000607251.1
FGF14-IT1
FGF14 intronic transcript 1 (non-protein coding)
chr14_+_76776957 1.380 ENST00000512784.1
ESRRB
estrogen-related receptor beta
chr19_+_6361440 1.368 ENST00000245816.4
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr12_-_109125285 1.367 ENST00000552871.1
ENST00000261401.3
CORO1C

coronin, actin binding protein, 1C

chr2_+_228337079 1.366 ENST00000409315.1
ENST00000373671.3
ENST00000409171.1
AGFG1


ArfGAP with FG repeats 1


chr17_+_42923686 1.363 ENST00000591513.1
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr21_-_46962379 1.354 ENST00000311124.4
ENST00000380010.4
SLC19A1

solute carrier family 19 (folate transporter), member 1

chr15_+_67430339 1.348 ENST00000439724.3
SMAD3
SMAD family member 3
chr5_-_137667459 1.345 ENST00000415130.2
ENST00000356505.3
ENST00000357274.3
ENST00000348983.3
ENST00000323760.6
CDC25C




cell division cycle 25C




chr11_+_44117741 1.343 ENST00000395673.3
ENST00000343631.3
EXT2

exostosin glycosyltransferase 2

chr20_-_44539538 1.334 ENST00000372420.1
PLTP
phospholipid transfer protein
chr17_-_39222131 1.334 ENST00000394015.2
KRTAP2-4
keratin associated protein 2-4
chr7_+_100136811 1.332 ENST00000300176.4
ENST00000262935.4
AGFG2

ArfGAP with FG repeats 2

chr3_-_28390120 1.331 ENST00000334100.6
AZI2
5-azacytidine induced 2
chr5_-_131563501 1.331 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
P4HA2




prolyl 4-hydroxylase, alpha polypeptide II




chr20_+_62694834 1.325 ENST00000415602.1
TCEA2
transcription elongation factor A (SII), 2
chr9_+_103235365 1.315 ENST00000374879.4
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr19_-_4124079 1.287 ENST00000394867.4
ENST00000262948.5
MAP2K2

mitogen-activated protein kinase kinase 2

chr8_+_27632083 1.280 ENST00000519637.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr12_-_48152428 1.271 ENST00000449771.2
ENST00000395358.3
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr1_-_245134273 1.270 ENST00000607453.1
RP11-156E8.1
Uncharacterized protein
chr20_-_36793663 1.270 ENST00000536701.1
ENST00000536724.1
TGM2

transglutaminase 2

chr6_-_105850937 1.261 ENST00000369110.3
PREP
prolyl endopeptidase
chr19_-_4723761 1.238 ENST00000597849.1
ENST00000598800.1
ENST00000602161.1
ENST00000597726.1
ENST00000601130.1
ENST00000262960.9
DPP9





dipeptidyl-peptidase 9





chrX_+_38420783 1.236 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7


tetraspanin 7


chr6_-_42185583 1.227 ENST00000053468.3
MRPS10
mitochondrial ribosomal protein S10
chr11_+_65407331 1.219 ENST00000527525.1
SIPA1
signal-induced proliferation-associated 1
chr9_+_124413873 1.217 ENST00000408936.3
DAB2IP
DAB2 interacting protein
chr20_+_18568537 1.206 ENST00000377452.3
DTD1
D-tyrosyl-tRNA deacylase 1
chr3_+_185300391 1.196 ENST00000545472.1
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr20_-_36793774 1.194 ENST00000361475.2
TGM2
transglutaminase 2
chr22_-_30234218 1.176 ENST00000307790.3
ENST00000542393.1
ENST00000397771.2
ASCC2


activating signal cointegrator 1 complex subunit 2


chr17_+_7210921 1.174 ENST00000573542.1
EIF5A
eukaryotic translation initiation factor 5A
chr16_+_69458537 1.163 ENST00000515314.1
ENST00000561792.1
ENST00000568237.1
CYB5B


cytochrome b5 type B (outer mitochondrial membrane)


chr20_+_44637526 1.160 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr16_+_28889801 1.160 ENST00000395503.4
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr11_+_63753883 1.154 ENST00000538426.1
ENST00000543004.1
OTUB1

OTU domain, ubiquitin aldehyde binding 1

chr17_-_49198095 1.153 ENST00000505279.1
SPAG9
sperm associated antigen 9
chr19_+_6361754 1.148 ENST00000597326.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr13_+_96204961 1.141 ENST00000299339.2
CLDN10
claudin 10
chr6_+_42018614 1.138 ENST00000465926.1
ENST00000482432.1
TAF8

TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa

chr1_+_10092890 1.118 ENST00000253251.8
ENST00000377157.3
UBE4B

ubiquitination factor E4B

chr17_+_7211656 1.112 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr3_-_28390298 1.111 ENST00000457172.1
AZI2
5-azacytidine induced 2
chr17_-_79139817 1.110 ENST00000326724.4
AATK
apoptosis-associated tyrosine kinase
chr22_+_37447771 1.105 ENST00000402077.3
ENST00000403888.3
ENST00000456470.1
KCTD17


potassium channel tetramerization domain containing 17


chr3_-_48672859 1.104 ENST00000395550.2
ENST00000455886.2
ENST00000431739.1
ENST00000426599.1
ENST00000383733.3
ENST00000420764.2
ENST00000337000.8
SLC26A6






solute carrier family 26 (anion exchanger), member 6






chr3_+_38206975 1.101 ENST00000446845.1
ENST00000311806.3
OXSR1

oxidative stress responsive 1

chr16_+_28889703 1.099 ENST00000357084.3
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr19_-_47354082 1.097 ENST00000593442.1
ENST00000263270.6
AP2S1

adaptor-related protein complex 2, sigma 1 subunit

chr2_+_173600514 1.093 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr17_-_76921459 1.087 ENST00000262768.7
TIMP2
TIMP metallopeptidase inhibitor 2
chr17_-_39968855 1.072 ENST00000355468.3
ENST00000590496.1
LEPREL4

leprecan-like 4

chr22_+_24309089 1.064 ENST00000215770.5
DDTL
D-dopachrome tautomerase-like
chr11_+_65405556 1.061 ENST00000534313.1
ENST00000533361.1
ENST00000526137.1
SIPA1


signal-induced proliferation-associated 1


chr19_-_47354023 1.060 ENST00000601649.1
ENST00000599990.1
ENST00000352203.4
AP2S1


adaptor-related protein complex 2, sigma 1 subunit


chr3_+_160117418 1.059 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
SMC4









structural maintenance of chromosomes 4









chr7_-_3083573 1.039 ENST00000396946.4
CARD11
caspase recruitment domain family, member 11
chr3_-_122102065 1.038 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
CCDC58


coiled-coil domain containing 58


chr1_+_160051319 1.033 ENST00000368088.3
KCNJ9
potassium inwardly-rectifying channel, subfamily J, member 9
chr17_-_39216344 1.026 ENST00000391418.2
KRTAP2-3
keratin associated protein 2-3
chr1_-_155880672 1.025 ENST00000609492.1
ENST00000368322.3
RIT1

Ras-like without CAAX 1

chr9_-_132515302 1.013 ENST00000340607.4
PTGES
prostaglandin E synthase
chr22_+_38093005 1.010 ENST00000406386.3
TRIOBP
TRIO and F-actin binding protein
chr7_-_767249 1.008 ENST00000403562.1
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr19_-_36001286 1.006 ENST00000602679.1
ENST00000492341.2
ENST00000472252.2
ENST00000602781.1
ENST00000402589.2
ENST00000458071.1
ENST00000436012.1
ENST00000443640.1
ENST00000450261.1
ENST00000467637.1
ENST00000480502.1
ENST00000474928.1
ENST00000414866.2
ENST00000392206.2
ENST00000488892.1
DMKN














dermokine














chr9_+_34653861 1.004 ENST00000556792.1
ENST00000318041.9
ENST00000378817.4
IL11RA


interleukin 11 receptor, alpha


chr11_-_2162162 1.004 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr19_-_15560730 0.998 ENST00000389282.4
ENST00000263381.7
WIZ

widely interspaced zinc finger motifs

chr14_+_37126765 0.998 ENST00000402703.2
PAX9
paired box 9
chr20_+_30467600 0.996 ENST00000375934.4
ENST00000375922.4
TTLL9

tubulin tyrosine ligase-like family, member 9

chr19_-_47353547 0.990 ENST00000601498.1
AP2S1
adaptor-related protein complex 2, sigma 1 subunit
chr20_-_50808236 0.989 ENST00000361387.2
ZFP64
ZFP64 zinc finger protein
chr20_+_43538756 0.987 ENST00000537323.1
ENST00000217073.2
PABPC1L

poly(A) binding protein, cytoplasmic 1-like

chr6_-_111888474 0.978 ENST00000368735.1
TRAF3IP2
TRAF3 interacting protein 2
chr5_+_133861339 0.973 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15


jade family PHD finger 2


chr17_+_7210852 0.973 ENST00000576930.1
EIF5A
eukaryotic translation initiation factor 5A
chr6_-_2971494 0.970 ENST00000380539.1
SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr22_+_46692638 0.967 ENST00000454366.1
GTSE1
G-2 and S-phase expressed 1
chr12_-_122241812 0.967 ENST00000538335.1
AC084018.1
AC084018.1
chr3_-_16555150 0.962 ENST00000334133.4
RFTN1
raftlin, lipid raft linker 1
chr3_-_28390415 0.961 ENST00000414162.1
ENST00000420543.2
AZI2

5-azacytidine induced 2

chr1_+_23037323 0.960 ENST00000544305.1
ENST00000374630.3
ENST00000400191.3
ENST00000374632.3
EPHB2



EPH receptor B2



chr17_-_1394940 0.953 ENST00000570984.2
ENST00000361007.2
MYO1C

myosin IC

chr8_+_97274119 0.951 ENST00000455950.2
PTDSS1
phosphatidylserine synthase 1
chr2_+_233243233 0.949 ENST00000392027.2
ALPP
alkaline phosphatase, placental
chrX_+_38420623 0.940 ENST00000378482.2
TSPAN7
tetraspanin 7
chr2_-_220408430 0.937 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr9_+_34179003 0.937 ENST00000545103.1
ENST00000543944.1
ENST00000536252.1
ENST00000540348.1
ENST00000297661.4
ENST00000379186.4
UBAP1





ubiquitin associated protein 1





chr9_+_125027127 0.935 ENST00000441707.1
ENST00000373723.5
ENST00000373729.1
MRRF


mitochondrial ribosome recycling factor


chr7_-_5569588 0.934 ENST00000417101.1
ACTB
actin, beta
chr5_-_132113036 0.929 ENST00000378706.1
SEPT8
septin 8
chr19_+_41882466 0.923 ENST00000436170.2
TMEM91
transmembrane protein 91
chr5_-_137667526 0.922 ENST00000503022.1
CDC25C
cell division cycle 25C
chr2_+_173600565 0.921 ENST00000397081.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr11_+_44117260 0.919 ENST00000358681.4
EXT2
exostosin glycosyltransferase 2
chr22_-_37584321 0.915 ENST00000397110.2
ENST00000337843.2
C1QTNF6

C1q and tumor necrosis factor related protein 6

chr8_-_11058847 0.914 ENST00000297303.4
ENST00000416569.2
XKR6

XK, Kell blood group complex subunit-related family, member 6

chr7_-_766879 0.913 ENST00000537384.1
ENST00000417852.1
PRKAR1B

protein kinase, cAMP-dependent, regulatory, type I, beta

chr2_-_136633940 0.912 ENST00000264156.2
MCM6
minichromosome maintenance complex component 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
1.5 4.4 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
1.5 4.4 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
1.4 4.1 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
1.4 4.1 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
1.0 7.7 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.9 3.4 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.8 2.5 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.8 4.0 GO:0044565 dendritic cell proliferation(GO:0044565)
0.8 2.4 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.8 2.3 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076)
0.7 1.5 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.7 2.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) cellular alkene metabolic process(GO:0043449)
0.7 2.7 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.6 5.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.6 2.4 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.6 3.0 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.5 1.6 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.5 2.2 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.5 1.6 GO:0042138 meiotic DNA double-strand break formation(GO:0042138) meiotic recombination checkpoint(GO:0051598)
0.5 1.5 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.5 2.0 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.5 2.9 GO:0034421 post-translational protein acetylation(GO:0034421)
0.5 1.4 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.5 2.3 GO:0042631 cellular response to water deprivation(GO:0042631)
0.5 1.4 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.4 4.2 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.4 2.5 GO:0071105 response to interleukin-11(GO:0071105)
0.4 2.0 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.4 1.2 GO:1900195 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.4 3.4 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.4 1.1 GO:0042938 dipeptide transport(GO:0042938)
0.4 1.1 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.3 1.0 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.3 2.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.3 2.0 GO:0061502 negative regulation of vesicle fusion(GO:0031339) early endosome to recycling endosome transport(GO:0061502)
0.3 1.3 GO:0042360 vitamin E metabolic process(GO:0042360)
0.3 2.9 GO:0006689 ganglioside catabolic process(GO:0006689)
0.3 5.4 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.3 1.8 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.3 2.3 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.3 2.2 GO:0046836 glycolipid transport(GO:0046836)
0.3 1.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.3 2.0 GO:0035897 proteolysis in other organism(GO:0035897)
0.2 3.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 0.7 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.2 1.2 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 2.7 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.2 1.0 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.2 0.7 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.2 2.6 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 1.9 GO:0060017 parathyroid gland development(GO:0060017)
0.2 2.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 1.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.2 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.2 2.4 GO:0034465 response to carbon monoxide(GO:0034465)
0.2 0.6 GO:0050894 determination of affect(GO:0050894)
0.2 1.1 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.2 0.8 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.2 9.5 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.2 1.7 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.2 0.6 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.2 3.9 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.2 1.4 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.2 1.0 GO:0030047 actin modification(GO:0030047)
0.2 0.8 GO:1901558 response to metformin(GO:1901558) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.2 1.6 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.2 0.6 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.2 2.3 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.2 0.6 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.2 2.4 GO:0044351 macropinocytosis(GO:0044351) phagosome-lysosome fusion(GO:0090385)
0.2 0.5 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.2 0.8 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430) Harderian gland development(GO:0070384)
0.2 1.0 GO:1903575 cornified envelope assembly(GO:1903575)
0.2 1.2 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.2 1.0 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.2 1.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 0.7 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.2 0.7 GO:0071484 cellular response to light intensity(GO:0071484)
0.2 0.8 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.2 1.1 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.2 0.5 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2 1.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.2 0.5 GO:0007518 myoblast fate determination(GO:0007518)
0.2 1.0 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 1.9 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.2 0.9 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.2 1.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 0.5 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.2 3.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.2 3.2 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.2 1.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2 0.9 GO:0051012 microtubule sliding(GO:0051012)
0.2 0.5 GO:0006258 UDP-glucose catabolic process(GO:0006258) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.6 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 1.7 GO:0033227 dsRNA transport(GO:0033227)
0.1 1.7 GO:0032790 ribosome disassembly(GO:0032790)
0.1 1.0 GO:1904526 regulation of microtubule binding(GO:1904526)
0.1 1.4 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 0.7 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.1 1.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.7 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.4 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.5 GO:0014040 regulation of Schwann cell differentiation(GO:0014038) positive regulation of Schwann cell differentiation(GO:0014040)
0.1 0.8 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.4 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 1.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 2.0 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 0.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.4 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.6 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 1.6 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.7 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 2.2 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.1 0.7 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 0.3 GO:1901207 regulation of heart looping(GO:1901207)
0.1 1.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 1.2 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.1 1.2 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.9 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.1 0.8 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 1.0 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.1 6.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 0.6 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 1.4 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.4 GO:0009227 nucleotide-sugar catabolic process(GO:0009227)
0.1 0.8 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.9 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.5 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.4 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 1.0 GO:0070970 interleukin-2 secretion(GO:0070970)
0.1 1.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.8 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.8 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 0.4 GO:0035617 stress granule disassembly(GO:0035617)
0.1 2.9 GO:0007020 microtubule nucleation(GO:0007020)
0.1 1.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.9 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.9 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.7 GO:2000580 regulation of microtubule motor activity(GO:2000574) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.8 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.1 0.3 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.4 GO:0000023 maltose metabolic process(GO:0000023)
0.1 0.7 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.5 GO:0015811 L-cystine transport(GO:0015811)
0.1 1.1 GO:0017085 response to insecticide(GO:0017085)
0.1 0.5 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.2 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.7 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.4 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.4 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 1.3 GO:0090344 negative regulation of cell aging(GO:0090344)
0.1 0.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.4 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.1 0.6 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.1 0.1 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.1 0.5 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 1.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.9 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 0.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.4 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.9 GO:0032025 response to cobalt ion(GO:0032025)
0.1 0.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 2.3 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1 0.3 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 2.5 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.1 0.7 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.1 0.5 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.1 0.5 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 2.4 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 1.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 1.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.3 GO:0015862 uridine transport(GO:0015862)
0.1 0.9 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.1 0.7 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 1.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.5 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 1.6 GO:0030728 ovulation(GO:0030728)
0.1 0.4 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.2 GO:0009635 response to herbicide(GO:0009635)
0.1 0.6 GO:0003416 endochondral bone growth(GO:0003416) bone growth(GO:0098868)
0.1 0.6 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.3 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.1 0.7 GO:0015074 DNA integration(GO:0015074)
0.1 0.9 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 0.1 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.0 1.5 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:1904760 myofibroblast differentiation(GO:0036446) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) regulation of myofibroblast differentiation(GO:1904760)
0.0 0.8 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.4 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 1.0 GO:0001783 B cell apoptotic process(GO:0001783)
0.0 0.4 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 2.4 GO:0043525 positive regulation of neuron apoptotic process(GO:0043525)
0.0 1.5 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 1.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 1.4 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.7 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.2 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.2 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.5 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.4 GO:0050957 equilibrioception(GO:0050957)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.3 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.2 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.2 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.0 0.2 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 1.4 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.2 GO:1901569 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 2.4 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 1.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.2 GO:0072233 thick ascending limb development(GO:0072023) DCT cell differentiation(GO:0072069) metanephric thick ascending limb development(GO:0072233) metanephric DCT cell differentiation(GO:0072240)
0.0 0.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.5 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.5 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.4 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 1.4 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.4 GO:0038007 netrin-activated signaling pathway(GO:0038007) negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 1.1 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.5 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.5 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.2 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 4.0 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 0.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.9 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.5 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.6 GO:0016180 snRNA processing(GO:0016180)
0.0 1.3 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.0 0.4 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.6 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.9 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 4.4 GO:0031424 keratinization(GO:0031424)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:0035962 response to interleukin-13(GO:0035962)
0.0 0.7 GO:0006040 amino sugar metabolic process(GO:0006040)
0.0 0.5 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 1.6 GO:0008344 adult locomotory behavior(GO:0008344)
0.0 0.9 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.7 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 1.5 GO:0030834 regulation of actin filament depolymerization(GO:0030834)
0.0 0.1 GO:0014063 negative regulation of glutamate secretion(GO:0014050) negative regulation of serotonin secretion(GO:0014063)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.0 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 1.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.0 0.1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.7 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.8 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.9 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.8 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.9 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.5 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.7 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0014029 neural crest formation(GO:0014029)
0.0 1.8 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.3 GO:0007614 short-term memory(GO:0007614)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 1.4 GO:0030516 regulation of axon extension(GO:0030516)
0.0 1.3 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.3 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.0 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.3 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.6 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.4 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.0 0.1 GO:0007512 adult heart development(GO:0007512)
0.0 0.1 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 1.4 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.3 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.8 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.5 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.7 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0048243 norepinephrine secretion(GO:0048243)
0.0 0.4 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 1.0 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.1 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.3 GO:0032094 response to food(GO:0032094)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 1.2 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.5 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.8 2.4 GO:0031523 Myb complex(GO:0031523)
0.7 2.2 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.7 2.9 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.7 2.2 GO:0005607 laminin-2 complex(GO:0005607)
0.6 7.3 GO:0005642 annulate lamellae(GO:0005642)
0.6 2.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.6 3.5 GO:0070435 Shc-EGFR complex(GO:0070435)
0.4 1.2 GO:1990032 parallel fiber(GO:1990032)
0.4 3.0 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.4 1.5 GO:0071001 U4/U6 snRNP(GO:0071001)
0.3 2.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.3 4.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.3 2.0 GO:0035976 AP1 complex(GO:0035976)
0.2 1.0 GO:0045160 myosin I complex(GO:0045160)
0.2 0.7 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.2 2.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 0.7 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.2 0.9 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 0.9 GO:0033186 CAF-1 complex(GO:0033186)
0.2 3.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 1.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 0.8 GO:0043293 apoptosome(GO:0043293)
0.2 0.9 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 2.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.2 2.0 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 1.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2 0.5 GO:0071159 NF-kappaB complex(GO:0071159)
0.2 2.6 GO:0031209 SCAR complex(GO:0031209)
0.2 2.1 GO:0016600 flotillin complex(GO:0016600)
0.2 2.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 2.0 GO:0032039 integrator complex(GO:0032039)
0.1 3.2 GO:0030122 AP-2 adaptor complex(GO:0030122) endolysosome membrane(GO:0036020)
0.1 2.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.1 GO:0000796 condensin complex(GO:0000796)
0.1 1.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.8 GO:0000800 lateral element(GO:0000800)
0.1 1.4 GO:0097433 dense body(GO:0097433)
0.1 2.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.9 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.3 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.1 1.2 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.8 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 3.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 3.1 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 0.5 GO:1990769 proximal neuron projection(GO:1990769)
0.1 1.4 GO:0005869 dynactin complex(GO:0005869)
0.1 0.4 GO:0097443 sorting endosome(GO:0097443)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.8 GO:0098845 postsynaptic endosome(GO:0098845)
0.1 4.7 GO:0001772 immunological synapse(GO:0001772)
0.1 1.0 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.7 GO:0042587 glycogen granule(GO:0042587)
0.1 1.8 GO:0030658 transport vesicle membrane(GO:0030658)
0.1 5.9 GO:0045095 keratin filament(GO:0045095)
0.1 0.9 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.4 GO:0014802 terminal cisterna(GO:0014802)
0.1 1.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.9 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 2.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 0.8 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.5 GO:0071986 Ragulator complex(GO:0071986)
0.1 2.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.9 GO:0042555 MCM complex(GO:0042555)
0.1 0.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.5 GO:0005638 lamin filament(GO:0005638)
0.1 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.3 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.1 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.5 GO:0044327 dendritic spine head(GO:0044327)
0.0 5.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 4.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.3 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.5 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 4.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 3.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.9 GO:0031105 septin complex(GO:0031105)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.7 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 1.5 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 5.0 GO:0031985 Golgi cisterna(GO:0031985)
0.0 1.8 GO:0032420 stereocilium(GO:0032420)
0.0 13.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 4.7 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.6 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 19.0 GO:0005925 focal adhesion(GO:0005925)
0.0 2.3 GO:0005902 microvillus(GO:0005902)
0.0 3.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.9 GO:0005795 Golgi stack(GO:0005795)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 3.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 4.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 7.7 GO:0005819 spindle(GO:0005819)
0.0 1.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.6 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 0.8 GO:0005768 endosome(GO:0005768)
0.0 1.1 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.0 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 3.4 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
1.4 4.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
1.2 4.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.7 4.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.7 4.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.6 3.0 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.6 2.3 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.6 1.7 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.5 3.5 GO:0048408 epidermal growth factor binding(GO:0048408)
0.5 2.0 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.5 9.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.5 3.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.5 2.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.5 1.9 GO:0017089 glycolipid transporter activity(GO:0017089)
0.5 1.4 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.5 3.6 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.5 1.4 GO:0008518 reduced folate carrier activity(GO:0008518)
0.4 1.7 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.4 2.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.4 4.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.4 1.2 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.4 1.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.4 2.9 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 1.0 GO:0070984 SET domain binding(GO:0070984)
0.3 2.9 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.3 1.9 GO:0034046 poly(G) binding(GO:0034046)
0.3 0.9 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.3 2.4 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.3 0.9 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.3 1.4 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.3 3.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.3 1.1 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.3 1.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.3 1.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.2 2.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 2.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.2 2.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 0.6 GO:0031877 somatostatin receptor binding(GO:0031877)
0.2 6.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 0.8 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.2 1.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 2.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 1.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 2.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.2 4.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 0.6 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.2 1.6 GO:1901612 cardiolipin binding(GO:1901612)
0.2 0.5 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.2 1.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.2 2.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.2 0.6 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.2 2.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 0.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 0.5 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.2 2.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 3.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 2.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.6 GO:0048185 activin binding(GO:0048185)
0.1 1.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.4 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 1.5 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.5 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 3.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 1.0 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.7 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.4 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.9 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 1.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.6 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 1.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.0 GO:0045159 myosin II binding(GO:0045159)
0.1 1.9 GO:0032052 bile acid binding(GO:0032052)
0.1 1.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 5.2 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.3 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 0.3 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 3.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.9 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 2.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.9 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 1.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 3.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.8 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.4 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 0.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 1.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.3 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.3 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.4 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.1 0.5 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.2 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 2.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.3 GO:0016936 galactoside binding(GO:0016936)
0.1 0.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.7 GO:0017166 vinculin binding(GO:0017166)
0.1 0.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.8 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 1.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.2 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 2.2 GO:0030552 cAMP binding(GO:0030552)
0.1 0.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 3.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 1.2 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.2 GO:0043398 HLH domain binding(GO:0043398)
0.1 1.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 2.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.9 GO:0035173 histone kinase activity(GO:0035173)
0.1 1.9 GO:0016866 intramolecular transferase activity(GO:0016866)
0.1 0.7 GO:0016301 kinase activity(GO:0016301)
0.1 0.3 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.8 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 1.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.4 GO:0003774 motor activity(GO:0003774)
0.0 0.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.9 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 1.0 GO:0050700 CARD domain binding(GO:0050700)
0.0 2.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 2.0 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 1.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.9 GO:0043495 protein anchor(GO:0043495)
0.0 1.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.0 0.8 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 2.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 16.4 GO:0005525 GTP binding(GO:0005525)
0.0 9.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 5.4 GO:0002020 protease binding(GO:0002020)
0.0 0.4 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 3.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 2.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 1.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.5 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 4.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.7 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 2.0 GO:0005179 hormone activity(GO:0005179)
0.0 1.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.7 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 2.4 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.5 GO:0008066 glutamate receptor activity(GO:0008066)
0.0 0.4 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 4.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 12.2 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.2 4.1 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.2 4.3 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.1 4.3 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.1 1.3 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 3.1 PID_CONE_PATHWAY Visual signal transduction: Cones
0.1 5.8 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 2.2 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.1 2.5 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 1.8 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 2.2 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.1 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.1 2.6 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.5 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.6 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.1 3.2 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 3.6 PID_AURORA_A_PATHWAY Aurora A signaling
0.1 0.6 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 0.9 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 0.9 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.5 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.1 2.7 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.9 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 2.4 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 2.0 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 1.7 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.2 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.4 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 1.0 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.3 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.0 ST_ADRENERGIC Adrenergic Pathway
0.0 1.9 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.8 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 11.3 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.8 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 3.1 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.4 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.7 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 0.4 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 1.4 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 PID_FGF_PATHWAY FGF signaling pathway
0.0 1.5 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.5 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 0.9 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.4 PID_BCR_5PATHWAY BCR signaling pathway
0.0 0.4 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.1 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 1.0 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.2 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 PID_P73PATHWAY p73 transcription factor network
0.0 0.5 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID_MYC_PATHWAY C-MYC pathway
0.0 0.9 PID_RHOA_REG_PATHWAY Regulation of RhoA activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.6 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 5.8 REACTOME_SHC_MEDIATED_SIGNALLING Genes involved in SHC-mediated signalling
0.2 9.3 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.2 7.3 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.2 4.9 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.2 3.1 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 5.3 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 8.5 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.2 4.1 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 3.2 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 2.5 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.3 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 2.3 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 2.1 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.1 1.6 REACTOME_OPSINS Genes involved in Opsins
0.1 1.7 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.4 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 4.3 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.1 2.3 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.9 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.6 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 3.8 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.1 1.3 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 2.0 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.8 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 0.9 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.9 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 0.6 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.1 2.2 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.9 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.2 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.1 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.8 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 1.3 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.5 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 2.0 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 0.9 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.4 REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 2.0 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.9 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.8 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.4 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.9 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.8 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME_PROSTANOID_LIGAND_RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 3.7 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 1.3 REACTOME_TRIGLYCERIDE_BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 1.4 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 4.0 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.9 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 1.6 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.6 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.3 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.7 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.0 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.0 3.4 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.7 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.2 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.8 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 1.9 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.9 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.9 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 2.1 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.6 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.6 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.9 REACTOME_CIRCADIAN_CLOCK Genes involved in Circadian Clock
0.0 0.3 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.1 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.1 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.4 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.7 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.9 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.4 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.2 REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
0.0 0.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis