Motif ID: SOX11
Z-value: 0.660
Transcription factors associated with SOX11:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| SOX11 | ENSG00000176887.5 | SOX11 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SOX11 | hg19_v2_chr2_+_5832799_5832799 | -0.25 | 2.5e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 5.7 | GO:0009441 | glycolate metabolic process(GO:0009441) |
| 0.4 | 2.2 | GO:0002399 | MHC class II protein complex assembly(GO:0002399) |
| 0.2 | 0.6 | GO:0030505 | inorganic diphosphate transport(GO:0030505) |
| 0.2 | 0.5 | GO:0034239 | macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241) |
| 0.1 | 0.8 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.1 | 0.3 | GO:0071418 | cellular response to amine stimulus(GO:0071418) |
| 0.1 | 0.4 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 0.1 | 0.6 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.1 | 0.2 | GO:0007231 | osmosensory signaling pathway(GO:0007231) |
| 0.1 | 0.3 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.0 | 0.5 | GO:0061088 | regulation of sequestering of zinc ion(GO:0061088) |
| 0.0 | 0.1 | GO:0006624 | vacuolar protein processing(GO:0006624) |
| 0.0 | 0.2 | GO:1903788 | mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788) |
| 0.0 | 0.4 | GO:0032277 | negative regulation of gonadotropin secretion(GO:0032277) |
| 0.0 | 0.2 | GO:0001692 | histamine metabolic process(GO:0001692) |
| 0.0 | 0.2 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.0 | 2.1 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
| 0.0 | 0.2 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
| 0.0 | 0.1 | GO:2000645 | negative regulation of receptor catabolic process(GO:2000645) |
| 0.0 | 0.2 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 0.0 | 0.1 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
| 0.0 | 0.2 | GO:0055096 | lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) |
| 0.0 | 0.2 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.0 | 0.2 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 0.0 | 0.2 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 0.0 | 0.4 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.0 | 2.2 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
| 0.0 | 0.4 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 0.0 | 1.4 | GO:0050999 | regulation of nitric-oxide synthase activity(GO:0050999) |
| 0.0 | 0.5 | GO:0045332 | phospholipid translocation(GO:0045332) |
| 0.0 | 0.2 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 0.0 | 0.4 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.0 | 1.4 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.0 | 0.8 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.0 | 0.9 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 2.3 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 0.0 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) protein auto-ADP-ribosylation(GO:0070213) |
| 0.0 | 0.5 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.0 | 0.1 | GO:0033227 | dsRNA transport(GO:0033227) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.9 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 5.7 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.1 | 0.3 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 0.0 | 0.1 | GO:0034680 | integrin alpha10-beta1 complex(GO:0034680) |
| 0.0 | 0.1 | GO:0036398 | TCR signalosome(GO:0036398) |
| 0.0 | 0.2 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.0 | 1.1 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.0 | 0.2 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.0 | 0.1 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.0 | 0.1 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.0 | 0.2 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 1.1 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 0.1 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 5.7 | GO:0016899 | oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899) |
| 0.3 | 2.1 | GO:0004127 | cytidylate kinase activity(GO:0004127) |
| 0.1 | 0.4 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
| 0.1 | 0.8 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
| 0.1 | 0.6 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
| 0.1 | 0.3 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
| 0.1 | 0.2 | GO:0030366 | molybdopterin synthase activity(GO:0030366) |
| 0.1 | 1.9 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.1 | 0.5 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
| 0.1 | 0.2 | GO:0017129 | triglyceride binding(GO:0017129) |
| 0.0 | 0.3 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.0 | 0.2 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 0.0 | 0.8 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.0 | 0.2 | GO:0047961 | glycine N-acyltransferase activity(GO:0047961) |
| 0.0 | 0.8 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 0.1 | GO:0050309 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 0.0 | 0.5 | GO:0005549 | odorant binding(GO:0005549) |
| 0.0 | 0.4 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.0 | 0.2 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.0 | 0.1 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.0 | 0.1 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.0 | 0.4 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 0.5 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.1 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.0 | 0.4 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.0 | 0.5 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.8 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 0.0 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 0.0 | 0.9 | GO:0004984 | olfactory receptor activity(GO:0004984) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.2 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 0.8 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.2 | REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.1 | 0.6 | REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.0 | 1.4 | REACTOME_ENOS_ACTIVATION_AND_REGULATION | Genes involved in eNOS activation and regulation |
| 0.0 | 0.4 | REACTOME_OPSINS | Genes involved in Opsins |
| 0.0 | 0.5 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 5.6 | REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.0 | 0.7 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 0.4 | REACTOME_REGULATION_OF_COMPLEMENT_CASCADE | Genes involved in Regulation of Complement cascade |
| 0.0 | 1.0 | REACTOME_OLFACTORY_SIGNALING_PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 0.1 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
