Motif ID: SOX30

Z-value: 0.379


Transcription factors associated with SOX30:

Gene SymbolEntrez IDGene Name
SOX30 ENSG00000039600.6 SOX30

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SOX30hg19_v2_chr5_-_157079428_157079452,
hg19_v2_chr5_-_157079372_157079395		-0.213.2e-01Click!


Activity profile for motif SOX30.

activity profile for motif SOX30


Sorted Z-values histogram for motif SOX30

Sorted Z-values for motif SOX30



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX30

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_28270795 1.472 ENST00000545014.1
 ARMC4
armadillo repeat containing 4
chr3_-_19988462 1.064 ENST00000344838.4
 EFHB
EF-hand domain family, member B
chr6_+_131958436 1.009 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
 ENPP3



ectonucleotide pyrophosphatase/phosphodiesterase 3



chr1_+_47489240 0.959 ENST00000371901.3
 CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr6_-_139613269 0.868 ENST00000358430.3
 TXLNB
taxilin beta
chr12_-_10282836 0.840 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
 CLEC7A


C-type lectin domain family 7, member A


chr3_+_181429704 0.596 ENST00000431565.2
ENST00000325404.1
 SOX2

SRY (sex determining region Y)-box 2

chr4_-_70725856 0.573 ENST00000226444.3
 SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr4_+_77356248 0.514 ENST00000296043.6
 SHROOM3
shroom family member 3
chr8_+_24151553 0.486 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
 ADAM28


ADAM metallopeptidase domain 28


chr5_-_160279207 0.457 ENST00000327245.5
 ATP10B
ATPase, class V, type 10B
chr6_-_134639180 0.447 ENST00000367858.5
 SGK1
serum/glucocorticoid regulated kinase 1
chr11_-_75236867 0.422 ENST00000376282.3
ENST00000336898.3
 GDPD5

glycerophosphodiester phosphodiesterase domain containing 5

chr8_+_105352050 0.418 ENST00000297581.2
 DCSTAMP
dendrocyte expressed seven transmembrane protein
chr5_+_140235469 0.414 ENST00000506939.2
ENST00000307360.5
 PCDHA10

protocadherin alpha 10

chr12_-_10282742 0.398 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
 CLEC7A


C-type lectin domain family 7, member A


chr12_-_10282681 0.394 ENST00000533022.1
 CLEC7A
C-type lectin domain family 7, member A
chr2_+_232573208 0.355 ENST00000409115.3
 PTMA
prothymosin, alpha
chr10_+_35415851 0.346 ENST00000374726.3
 CREM
cAMP responsive element modulator
chr10_+_70480963 0.344 ENST00000265872.6
ENST00000535016.1
ENST00000538031.1
ENST00000543719.1
ENST00000539539.1
ENST00000543225.1
ENST00000536012.1
ENST00000494903.2
 CCAR1







cell division cycle and apoptosis regulator 1







chr2_+_232573222 0.332 ENST00000341369.7
ENST00000409683.1
 PTMA

prothymosin, alpha

chr11_+_63137251 0.324 ENST00000310969.4
ENST00000279178.3
 SLC22A9

solute carrier family 22 (organic anion transporter), member 9

chr11_-_85430204 0.320 ENST00000389958.3
ENST00000527794.1
 SYTL2

synaptotagmin-like 2

chr11_-_85430163 0.303 ENST00000529581.1
ENST00000533577.1
 SYTL2

synaptotagmin-like 2

chr2_-_157198860 0.299 ENST00000409572.1
 NR4A2
nuclear receptor subfamily 4, group A, member 2
chr8_+_24151620 0.260 ENST00000437154.2
 ADAM28
ADAM metallopeptidase domain 28
chrX_-_117107542 0.245 ENST00000371878.1
 KLHL13
kelch-like family member 13
chr6_-_49712123 0.232 ENST00000263045.4
 CRISP3
cysteine-rich secretory protein 3
chr4_-_87028478 0.232 ENST00000515400.1
ENST00000395157.3
 MAPK10

mitogen-activated protein kinase 10

chr11_+_36317830 0.223 ENST00000530639.1
 PRR5L
proline rich 5 like
chr6_+_126240442 0.219 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
 NCOA7


nuclear receptor coactivator 7


chr11_-_85430088 0.205 ENST00000533057.1
ENST00000533892.1
 SYTL2

synaptotagmin-like 2

chrX_-_24690771 0.204 ENST00000379145.1
 PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr2_+_179184955 0.193 ENST00000315022.2
 OSBPL6
oxysterol binding protein-like 6
chr7_-_92855762 0.191 ENST00000453812.2
ENST00000394468.2
 HEPACAM2

HEPACAM family member 2

chr5_+_170288856 0.177 ENST00000523189.1
 RANBP17
RAN binding protein 17
chr5_+_139175380 0.154 ENST00000274710.3
 PSD2
pleckstrin and Sec7 domain containing 2
chr1_+_240255166 0.150 ENST00000319653.9
 FMN2
formin 2
chr15_-_52944231 0.140 ENST00000546305.2
 FAM214A
family with sequence similarity 214, member A
chr12_-_10251576 0.138 ENST00000315330.4
 CLEC1A
C-type lectin domain family 1, member A
chr1_-_85930246 0.135 ENST00000426972.3
 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr17_-_38821373 0.135 ENST00000394052.3
 KRT222
keratin 222
chr4_+_113152978 0.129 ENST00000309703.6
 AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr18_+_7946941 0.126 ENST00000444013.1
 PTPRM
protein tyrosine phosphatase, receptor type, M
chr1_+_93913713 0.124 ENST00000604705.1
ENST00000370253.2
 FNBP1L

formin binding protein 1-like

chr3_+_140981456 0.122 ENST00000504264.1
 ACPL2
acid phosphatase-like 2
chr1_-_21503337 0.118 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
 EIF4G3



eukaryotic translation initiation factor 4 gamma, 3



chr13_-_41593425 0.117 ENST00000239882.3
 ELF1
E74-like factor 1 (ets domain transcription factor)
chr1_+_244998602 0.113 ENST00000411948.2
 COX20
COX20 cytochrome C oxidase assembly factor
chr5_-_82969405 0.109 ENST00000510978.1
 HAPLN1
hyaluronan and proteoglycan link protein 1
chr12_-_10251603 0.104 ENST00000457018.2
 CLEC1A
C-type lectin domain family 1, member A
chr22_-_30970560 0.099 ENST00000402369.1
ENST00000406361.1
 GAL3ST1

galactose-3-O-sulfotransferase 1

chr5_+_140729649 0.098 ENST00000523390.1
 PCDHGB1
protocadherin gamma subfamily B, 1
chr22_+_46449674 0.096 ENST00000381051.2
 FLJ27365
hsa-mir-4763
chr14_-_90420862 0.093 ENST00000556005.1
ENST00000555872.1
 EFCAB11

EF-hand calcium binding domain 11

chr5_-_146461027 0.092 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
 PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr14_-_90421028 0.091 ENST00000267544.9
ENST00000316738.7
ENST00000538485.2
ENST00000556609.1
 EFCAB11



EF-hand calcium binding domain 11



chr11_-_18548426 0.087 ENST00000357193.3
ENST00000536719.1
 TSG101

tumor susceptibility 101

chr3_-_165555200 0.087 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
 BCHE



butyrylcholinesterase



chr12_+_80750134 0.080 ENST00000546620.1
 OTOGL
otogelin-like
chr5_+_140772381 0.076 ENST00000398604.2
 PCDHGA8
protocadherin gamma subfamily A, 8
chr4_-_69111401 0.073 ENST00000332644.5
 TMPRSS11B
transmembrane protease, serine 11B
chr5_+_140787600 0.071 ENST00000520790.1
 PCDHGB6
protocadherin gamma subfamily B, 6
chr11_+_125365110 0.071 ENST00000527818.1
 AP000708.1
AP000708.1
chr2_-_158182410 0.070 ENST00000419116.2
ENST00000410096.1
 ERMN

ermin, ERM-like protein

chr1_-_26324534 0.069 ENST00000374284.1
ENST00000441420.1
ENST00000374282.3
 PAFAH2


platelet-activating factor acetylhydrolase 2, 40kDa


chr1_-_167883327 0.068 ENST00000476818.2
ENST00000367851.4
ENST00000367848.1
 ADCY10


adenylate cyclase 10 (soluble)


chr11_-_102323740 0.068 ENST00000398136.2
 TMEM123
transmembrane protein 123
chr5_+_140593509 0.067 ENST00000341948.4
 PCDHB13
protocadherin beta 13
chr10_+_35416223 0.064 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
 CREM





cAMP responsive element modulator





chr5_+_38148582 0.064 ENST00000508853.1
 CTD-2207A17.1
CTD-2207A17.1
chr10_+_35416090 0.062 ENST00000354759.3
 CREM
cAMP responsive element modulator
chr17_+_47448102 0.060 ENST00000576461.1
 RP11-81K2.1
Uncharacterized protein
chr2_-_162931052 0.059 ENST00000360534.3
 DPP4
dipeptidyl-peptidase 4
chr1_+_40942887 0.058 ENST00000372706.1
 ZFP69
ZFP69 zinc finger protein
chrY_+_15016013 0.058 ENST00000360160.4
ENST00000454054.1
 DDX3Y

DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked

chr1_+_185703513 0.057 ENST00000271588.4
ENST00000367492.2
 HMCN1

hemicentin 1

chr14_+_36295504 0.057 ENST00000216807.7
 BRMS1L
breast cancer metastasis-suppressor 1-like
chr2_+_99953816 0.054 ENST00000289371.6
 EIF5B
eukaryotic translation initiation factor 5B
chr4_+_54243862 0.054 ENST00000306932.6
 FIP1L1
factor interacting with PAPOLA and CPSF1
chr12_-_10251539 0.052 ENST00000420265.2
 CLEC1A
C-type lectin domain family 1, member A
chr6_-_11779174 0.047 ENST00000379413.2
 ADTRP
androgen-dependent TFPI-regulating protein
chr19_-_44439387 0.046 ENST00000269973.5
 ZNF45
zinc finger protein 45
chr6_-_11779014 0.044 ENST00000229583.5
 ADTRP
androgen-dependent TFPI-regulating protein
chr17_+_67498538 0.043 ENST00000589647.1
 MAP2K6
mitogen-activated protein kinase kinase 6
chr10_+_35415719 0.042 ENST00000474362.1
ENST00000374721.3
 CREM

cAMP responsive element modulator

chr8_+_42195972 0.042 ENST00000532157.1
ENST00000265421.4
ENST00000520008.1
 POLB


polymerase (DNA directed), beta


chr15_+_76629064 0.040 ENST00000290759.4
 ISL2
ISL LIM homeobox 2
chr11_-_102576537 0.040 ENST00000260229.4
 MMP27
matrix metallopeptidase 27
chr4_+_71457970 0.039 ENST00000322937.6
 AMBN
ameloblastin (enamel matrix protein)
chr1_-_167883353 0.036 ENST00000545172.1
 ADCY10
adenylate cyclase 10 (soluble)
chr3_-_8686479 0.036 ENST00000544814.1
ENST00000427408.1
 SSUH2

ssu-2 homolog (C. elegans)

chr5_-_134734901 0.036 ENST00000312469.4
ENST00000423969.2
 H2AFY

H2A histone family, member Y

chr19_-_17375541 0.036 ENST00000252597.3
 USHBP1
Usher syndrome 1C binding protein 1
chr3_-_18466026 0.033 ENST00000417717.2
 SATB1
SATB homeobox 1
chr1_-_200379129 0.033 ENST00000367353.1
 ZNF281
zinc finger protein 281
chr11_-_89224638 0.031 ENST00000535633.1
ENST00000263317.4
 NOX4

NADPH oxidase 4

chr11_-_102323489 0.028 ENST00000361236.3
 TMEM123
transmembrane protein 123
chr4_+_71458012 0.025 ENST00000449493.2
 AMBN
ameloblastin (enamel matrix protein)
chr16_+_87636474 0.021 ENST00000284262.2
 JPH3
junctophilin 3
chr10_+_35415978 0.019 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
 CREM


cAMP responsive element modulator


chr1_-_200379180 0.017 ENST00000294740.3
 ZNF281
zinc finger protein 281
chr10_+_35484793 0.013 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
 CREM




cAMP responsive element modulator




chr6_+_22146851 0.010 ENST00000606197.1
 CASC15
cancer susceptibility candidate 15 (non-protein coding)
chr22_-_43485381 0.009 ENST00000331018.7
ENST00000266254.7
ENST00000445824.1
 TTLL1


tubulin tyrosine ligase-like family, member 1


chr16_+_20499024 0.007 ENST00000593357.1
 AC137056.1
Uncharacterized protein; cDNA FLJ34659 fis, clone KIDNE2018863
chr7_-_11871815 0.006 ENST00000423059.4
 THSD7A
thrombospondin, type I, domain containing 7A
chr2_-_37899323 0.003 ENST00000295324.3
ENST00000457889.1
 CDC42EP3

CDC42 effector protein (Rho GTPase binding) 3

chr1_+_185014496 0.002 ENST00000367510.3
 RNF2
ring finger protein 2
chr4_-_176733897 0.000 ENST00000393658.2
 GPM6A
glycoprotein M6A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.2 0.6 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.4 GO:0034239 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.1 1.5 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.1 0.3 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 1.6 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.6 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 0.8 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.4 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.1 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.4 GO:0045176 apical protein localization(GO:0045176)
0.0 0.3 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 GO:0097546 ciliary base(GO:0097546)
0.0 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.6 GO:0050294 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 1.6 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 1.0 GO:0070330 aromatase activity(GO:0070330)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:0035198 miRNA binding(GO:0035198)
0.0 0.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors