Motif ID: SOX6

Z-value: 0.505


Transcription factors associated with SOX6:

Gene SymbolEntrez IDGene Name
SOX6 ENSG00000110693.11 SOX6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SOX6hg19_v2_chr11_-_16430399_16430440-0.232.7e-01Click!


Activity profile for motif SOX6.

activity profile for motif SOX6


Sorted Z-values histogram for motif SOX6

Sorted Z-values for motif SOX6



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_180018540 2.388 ENST00000292641.3
SCGB3A1
secretoglobin, family 3A, member 1
chr4_+_70861647 1.763 ENST00000246895.4
ENST00000381060.2
STATH

statherin

chr16_+_23765948 1.547 ENST00000300113.2
CHP2
calcineurin-like EF-hand protein 2
chr20_-_39317868 1.350 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr10_+_115511213 1.291 ENST00000361048.1
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr5_+_140213815 1.228 ENST00000525929.1
ENST00000378125.3
PCDHA7

protocadherin alpha 7

chr5_+_140254884 1.015 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr14_-_106926724 1.003 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr2_-_86564776 0.983 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1


receptor accessory protein 1


chr6_-_29527702 0.980 ENST00000377050.4
UBD
ubiquitin D
chr12_-_49582978 0.926 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr13_+_24144796 0.909 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr13_+_24144509 0.861 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr4_+_41614909 0.811 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1


LIM and calponin homology domains 1


chr6_-_139613269 0.760 ENST00000358430.3
TXLNB
taxilin beta
chr3_+_181429704 0.705 ENST00000431565.2
ENST00000325404.1
SOX2

SRY (sex determining region Y)-box 2

chr5_+_140235469 0.696 ENST00000506939.2
ENST00000307360.5
PCDHA10

protocadherin alpha 10

chr4_+_55524085 0.659 ENST00000412167.2
ENST00000288135.5
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr2_-_217560248 0.632 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr18_+_6729698 0.615 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr19_-_18717627 0.592 ENST00000392386.3
CRLF1
cytokine receptor-like factor 1
chr3_-_149510553 0.568 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ANKUB1


ankyrin repeat and ubiquitin domain containing 1


chr2_+_232573208 0.546 ENST00000409115.3
PTMA
prothymosin, alpha
chr4_+_41614720 0.545 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr10_-_62332357 0.544 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr10_-_13390270 0.543 ENST00000378614.4
ENST00000545675.1
ENST00000327347.5
SEPHS1


selenophosphate synthetase 1


chr3_-_114790179 0.532 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr2_-_118943930 0.518 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1


AC093901.1


chr22_+_39052632 0.515 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1



chibby homolog 1 (Drosophila)



chr1_+_14075865 0.507 ENST00000413440.1
PRDM2
PR domain containing 2, with ZNF domain
chr2_+_232573222 0.499 ENST00000341369.7
ENST00000409683.1
PTMA

prothymosin, alpha

chr8_+_24151553 0.485 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28


ADAM metallopeptidase domain 28


chr6_-_134639180 0.479 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr17_+_21729593 0.476 ENST00000581769.1
ENST00000584755.1
UBBP4

ubiquitin B pseudogene 4

chr9_-_130639997 0.475 ENST00000373176.1
AK1
adenylate kinase 1
chr11_-_69519410 0.464 ENST00000294312.3
FGF19
fibroblast growth factor 19
chr11_+_36317830 0.455 ENST00000530639.1
PRR5L
proline rich 5 like
chr15_+_74610894 0.454 ENST00000558821.1
ENST00000268082.4
CCDC33

coiled-coil domain containing 33

chr18_+_13218769 0.453 ENST00000399848.3
ENST00000361205.4
LDLRAD4

low density lipoprotein receptor class A domain containing 4

chr4_-_146101304 0.452 ENST00000447906.2
OTUD4
OTU domain containing 4
chr3_-_148939835 0.443 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr8_+_24151620 0.437 ENST00000437154.2
ADAM28
ADAM metallopeptidase domain 28
chr4_-_105416039 0.432 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr1_+_240255166 0.424 ENST00000319653.9
FMN2
formin 2
chr11_-_76155618 0.415 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr1_+_14075903 0.407 ENST00000343137.4
ENST00000503842.1
ENST00000407521.3
ENST00000505823.1
PRDM2



PR domain containing 2, with ZNF domain



chr9_-_130712995 0.402 ENST00000373084.4
FAM102A
family with sequence similarity 102, member A
chr11_-_75236867 0.397 ENST00000376282.3
ENST00000336898.3
GDPD5

glycerophosphodiester phosphodiesterase domain containing 5

chr5_-_124081008 0.396 ENST00000306315.5
ZNF608
zinc finger protein 608
chr2_-_157198860 0.393 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr12_-_10151773 0.387 ENST00000298527.6
ENST00000348658.4
CLEC1B

C-type lectin domain family 1, member B

chrX_+_130192318 0.384 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr6_-_24877490 0.384 ENST00000540914.1
ENST00000378023.4
FAM65B

family with sequence similarity 65, member B

chr17_+_21729899 0.378 ENST00000583708.1
UBBP4
ubiquitin B pseudogene 4
chrX_-_117107542 0.360 ENST00000371878.1
KLHL13
kelch-like family member 13
chr17_-_56065484 0.351 ENST00000581208.1
VEZF1
vascular endothelial zinc finger 1
chr6_+_72596604 0.350 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
RIMS1






regulating synaptic membrane exocytosis 1






chr16_+_2083265 0.341 ENST00000565855.1
ENST00000566198.1
SLC9A3R2

solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2

chr12_-_50294033 0.340 ENST00000552669.1
FAIM2
Fas apoptotic inhibitory molecule 2
chr12_-_49582593 0.339 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr2_+_27805880 0.334 ENST00000379717.1
ENST00000355467.4
ENST00000556601.1
ENST00000416005.2
ZNF512



zinc finger protein 512



chr17_+_26698677 0.330 ENST00000457710.3
SARM1
sterile alpha and TIR motif containing 1
chr1_-_32801825 0.312 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr7_-_50628745 0.311 ENST00000380984.4
ENST00000357936.5
ENST00000426377.1
DDC


dopa decarboxylase (aromatic L-amino acid decarboxylase)


chr15_-_52043722 0.309 ENST00000454181.2
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr2_+_61293021 0.308 ENST00000402291.1
KIAA1841
KIAA1841
chr6_-_49712123 0.306 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr10_+_70480963 0.305 ENST00000265872.6
ENST00000535016.1
ENST00000538031.1
ENST00000543719.1
ENST00000539539.1
ENST00000543225.1
ENST00000536012.1
ENST00000494903.2
CCAR1







cell division cycle and apoptosis regulator 1







chr6_+_122720681 0.304 ENST00000368455.4
ENST00000452194.1
HSF2

heat shock transcription factor 2

chr11_-_85430204 0.297 ENST00000389958.3
ENST00000527794.1
SYTL2

synaptotagmin-like 2

chr12_-_45270151 0.296 ENST00000429094.2
NELL2
NEL-like 2 (chicken)
chr11_-_76155700 0.292 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr11_-_85430163 0.278 ENST00000529581.1
ENST00000533577.1
SYTL2

synaptotagmin-like 2

chr8_+_105352050 0.277 ENST00000297581.2
DCSTAMP
dendrocyte expressed seven transmembrane protein
chr12_-_45270077 0.273 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2


NEL-like 2 (chicken)


chr7_+_69064300 0.270 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr11_-_130184555 0.268 ENST00000525842.1
ZBTB44
zinc finger and BTB domain containing 44
chr4_-_138453559 0.267 ENST00000511115.1
PCDH18
protocadherin 18
chr11_-_44971702 0.266 ENST00000533940.1
ENST00000533937.1
TP53I11

tumor protein p53 inducible protein 11

chr7_+_116312411 0.262 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET


met proto-oncogene


chr11_-_130184470 0.262 ENST00000357899.4
ENST00000397753.1
ZBTB44

zinc finger and BTB domain containing 44

chr16_-_73082274 0.261 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr11_+_125365110 0.260 ENST00000527818.1
AP000708.1
AP000708.1
chr19_-_5340730 0.250 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
PTPRS




protein tyrosine phosphatase, receptor type, S




chr15_-_82338460 0.243 ENST00000558133.1
ENST00000329713.4
MEX3B

mex-3 RNA binding family member B

chr2_+_42104692 0.240 ENST00000398796.2
ENST00000442214.1
AC104654.1

AC104654.1

chr3_-_167813672 0.239 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr9_-_124989804 0.239 ENST00000373755.2
ENST00000373754.2
LHX6

LIM homeobox 6

chr12_-_95945246 0.239 ENST00000258499.3
USP44
ubiquitin specific peptidase 44
chr1_+_152943122 0.234 ENST00000328051.2
SPRR4
small proline-rich protein 4
chr12_+_124997766 0.229 ENST00000543970.1
RP11-83B20.1
RP11-83B20.1
chr3_-_65583561 0.223 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr10_+_22605374 0.223 ENST00000448361.1
COMMD3
COMM domain containing 3
chr16_+_54964740 0.222 ENST00000394636.4
IRX5
iroquois homeobox 5
chr6_-_3227877 0.221 ENST00000259818.7
TUBB2B
tubulin, beta 2B class IIb
chr17_-_18950310 0.220 ENST00000573099.1
GRAP
GRB2-related adaptor protein
chr2_+_149402553 0.219 ENST00000258484.6
ENST00000409654.1
EPC2

enhancer of polycomb homolog 2 (Drosophila)

chr13_-_41593425 0.216 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr16_+_30205754 0.215 ENST00000354723.6
ENST00000355544.5
SULT1A3

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3

chr11_-_85430088 0.212 ENST00000533057.1
ENST00000533892.1
SYTL2

synaptotagmin-like 2

chr16_+_68573640 0.211 ENST00000398253.2
ENST00000573161.1
ZFP90

ZFP90 zinc finger protein

chr3_+_183353356 0.209 ENST00000242810.6
ENST00000493074.1
ENST00000437402.1
ENST00000454495.2
ENST00000473045.1
ENST00000468101.1
ENST00000427201.2
ENST00000482138.1
ENST00000454652.2
KLHL24








kelch-like family member 24








chr3_+_112930306 0.209 ENST00000495514.1
BOC
BOC cell adhesion associated, oncogene regulated
chr5_+_139175380 0.207 ENST00000274710.3
PSD2
pleckstrin and Sec7 domain containing 2
chr10_+_22605304 0.206 ENST00000456711.1
ENST00000444869.1
ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
COMMD3

COMMD3-BMI1


COMM domain containing 3

COMMD3-BMI1 readthrough


chr7_+_29234101 0.203 ENST00000435288.2
CHN2
chimerin 2
chr17_+_67498538 0.200 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr17_-_14683517 0.199 ENST00000379640.1
AC005863.1
AC005863.1
chr7_+_29234028 0.198 ENST00000222792.6
CHN2
chimerin 2
chr18_-_52989217 0.197 ENST00000570287.2
TCF4
transcription factor 4
chr20_+_60718785 0.196 ENST00000421564.1
ENST00000450482.1
ENST00000331758.3
SS18L1


synovial sarcoma translocation gene on chromosome 18-like 1


chr6_-_167040731 0.192 ENST00000265678.4
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr16_-_30798492 0.189 ENST00000262525.4
ZNF629
zinc finger protein 629
chr15_+_89631647 0.188 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
ABHD2


abhydrolase domain containing 2


chr19_-_51891209 0.184 ENST00000221973.3
ENST00000596399.1
LIM2

lens intrinsic membrane protein 2, 19kDa

chr17_-_9940058 0.183 ENST00000585266.1
GAS7
growth arrest-specific 7
chr20_-_1317555 0.182 ENST00000537552.1
AL136531.1
HCG2043693; Uncharacterized protein
chr9_-_98269481 0.179 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
PTCH1


patched 1


chr16_-_67970990 0.177 ENST00000358514.4
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr19_-_17571722 0.176 ENST00000301944.2
NXNL1
nucleoredoxin-like 1
chr22_+_29168652 0.175 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117



coiled-coil domain containing 117



chr18_-_74728998 0.173 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
MBP










myelin basic protein










chr9_+_101705893 0.173 ENST00000375001.3
COL15A1
collagen, type XV, alpha 1
chr15_-_88799948 0.172 ENST00000394480.2
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr1_+_9005917 0.172 ENST00000549778.1
ENST00000480186.3
ENST00000377443.2
ENST00000377436.3
ENST00000377442.2
CA6




carbonic anhydrase VI




chr15_+_89631381 0.168 ENST00000352732.5
ABHD2
abhydrolase domain containing 2
chrX_+_129473859 0.168 ENST00000424447.1
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chrX_-_101726732 0.168 ENST00000457521.2
ENST00000412230.2
ENST00000453326.2
NXF2B

TCP11X2
nuclear RNA export factor 2B

t-complex 11 family, X-linked 2
chr21_+_33784670 0.162 ENST00000300255.2
EVA1C
eva-1 homolog C (C. elegans)
chrX_+_101470280 0.162 ENST00000395088.2
ENST00000330252.5
ENST00000333110.5
NXF2

TCP11X1
nuclear RNA export factor 2

t-complex 11 family, X-linked 1
chr19_+_38397839 0.161 ENST00000222345.6
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr2_+_170590321 0.160 ENST00000392647.2
KLHL23
kelch-like family member 23
chr1_-_2461684 0.154 ENST00000378453.3
HES5
hes family bHLH transcription factor 5
chr1_+_200993071 0.153 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1

RP11-168O16.1

chr4_-_138453606 0.153 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18



protocadherin 18



chr18_+_13611763 0.150 ENST00000585931.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr14_+_23791159 0.148 ENST00000557702.1
PABPN1
poly(A) binding protein, nuclear 1
chr14_-_106518922 0.147 ENST00000390598.2
IGHV3-7
immunoglobulin heavy variable 3-7
chr12_-_5352315 0.145 ENST00000536518.1
RP11-319E16.1
RP11-319E16.1
chr5_-_114515734 0.145 ENST00000514154.1
ENST00000282369.3
TRIM36

tripartite motif containing 36

chr3_+_112930387 0.145 ENST00000485230.1
BOC
BOC cell adhesion associated, oncogene regulated
chr11_-_79151695 0.142 ENST00000278550.7
TENM4
teneurin transmembrane protein 4
chr17_-_19648683 0.142 ENST00000573368.1
ENST00000457500.2
ALDH3A1

aldehyde dehydrogenase 3 family, member A1

chr17_-_19648916 0.139 ENST00000444455.1
ENST00000439102.2
ALDH3A1

aldehyde dehydrogenase 3 family, member A1

chr7_+_87563458 0.138 ENST00000398204.4
ADAM22
ADAM metallopeptidase domain 22
chr13_-_95131923 0.137 ENST00000377028.5
ENST00000446125.1
DCT

dopachrome tautomerase

chr14_-_96830207 0.137 ENST00000359933.4
ATG2B
autophagy related 2B
chr2_+_46926326 0.136 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr7_+_69064566 0.136 ENST00000403018.2
AUTS2
autism susceptibility candidate 2
chr5_+_134094461 0.135 ENST00000452510.2
ENST00000354283.4
DDX46

DEAD (Asp-Glu-Ala-Asp) box polypeptide 46

chr1_-_21503337 0.134 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
EIF4G3



eukaryotic translation initiation factor 4 gamma, 3



chr20_-_3996036 0.129 ENST00000336095.6
RNF24
ring finger protein 24
chr5_-_146435501 0.129 ENST00000336640.6
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr6_+_13925098 0.127 ENST00000488300.1
ENST00000544682.1
ENST00000420478.2
RNF182


ring finger protein 182


chr12_-_88974236 0.126 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG


KIT ligand


chr19_-_10047219 0.126 ENST00000264833.4
OLFM2
olfactomedin 2
chr5_-_146435572 0.125 ENST00000394414.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chrX_-_45060135 0.124 ENST00000398000.2
ENST00000377934.4
CXorf36

chromosome X open reading frame 36

chr5_+_49962772 0.123 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8




poly (ADP-ribose) polymerase family, member 8




chr5_-_173043591 0.123 ENST00000285908.5
ENST00000480951.1
ENST00000311086.4
BOD1


biorientation of chromosomes in cell division 1


chr11_+_63706444 0.122 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
NAA40


N(alpha)-acetyltransferase 40, NatD catalytic subunit


chr1_+_147374915 0.121 ENST00000240986.4
GJA8
gap junction protein, alpha 8, 50kDa
chr1_+_244998602 0.120 ENST00000411948.2
COX20
COX20 cytochrome C oxidase assembly factor
chr11_+_196738 0.120 ENST00000325113.4
ENST00000342593.5
ODF3

outer dense fiber of sperm tails 3

chr4_-_87028478 0.120 ENST00000515400.1
ENST00000395157.3
MAPK10

mitogen-activated protein kinase 10

chr1_-_212004090 0.119 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr14_-_35344093 0.118 ENST00000382422.2
BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chrX_+_84499081 0.118 ENST00000276123.3
ZNF711
zinc finger protein 711
chr12_-_89919220 0.117 ENST00000549035.1
ENST00000393179.4
POC1B

POC1 centriolar protein B

chr15_+_52043758 0.116 ENST00000249700.4
ENST00000539962.2
TMOD2

tropomodulin 2 (neuronal)

chr9_+_108463234 0.116 ENST00000374688.1
TMEM38B
transmembrane protein 38B
chr3_-_8686479 0.115 ENST00000544814.1
ENST00000427408.1
SSUH2

ssu-2 homolog (C. elegans)

chr12_-_76817036 0.114 ENST00000546946.1
OSBPL8
oxysterol binding protein-like 8
chr21_+_38445539 0.114 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3





tetratricopeptide repeat domain 3





chr5_-_169725231 0.114 ENST00000046794.5
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_+_24286287 0.114 ENST00000334351.7
ENST00000374468.1
PNRC2

proline-rich nuclear receptor coactivator 2

chr19_-_17571613 0.112 ENST00000594663.1
CTD-2521M24.10
Uncharacterized protein
chr10_+_35415851 0.112 ENST00000374726.3
CREM
cAMP responsive element modulator
chr15_-_41166414 0.111 ENST00000220507.4
RHOV
ras homolog family member V
chr15_-_54025300 0.109 ENST00000559418.1
WDR72
WD repeat domain 72
chr6_-_107436473 0.107 ENST00000369042.1
BEND3
BEN domain containing 3
chr14_-_95236551 0.106 ENST00000238558.3
GSC
goosecoid homeobox
chrX_+_135579238 0.105 ENST00000535601.1
ENST00000448450.1
ENST00000425695.1
HTATSF1


HIV-1 Tat specific factor 1


chr1_+_249200395 0.105 ENST00000355360.4
ENST00000329291.5
ENST00000539153.1
PGBD2


piggyBac transposable element derived 2


chr1_-_182360498 0.105 ENST00000417584.2
GLUL
glutamate-ammonia ligase
chr4_+_159690218 0.102 ENST00000264433.6
FNIP2
folliculin interacting protein 2
chr1_-_207143802 0.102 ENST00000324852.4
ENST00000400962.3
FCAMR

Fc receptor, IgA, IgM, high affinity

chr17_+_21730180 0.102 ENST00000584398.1
UBBP4
ubiquitin B pseudogene 4
chr22_-_27014043 0.101 ENST00000215939.2
CRYBB1
crystallin, beta B1
chr19_-_44124019 0.101 ENST00000300811.3
ZNF428
zinc finger protein 428
chr16_-_15736881 0.101 ENST00000540441.2
KIAA0430
KIAA0430
chr18_+_7946941 0.100 ENST00000444013.1
PTPRM
protein tyrosine phosphatase, receptor type, M
chr17_+_64961026 0.100 ENST00000262138.3
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr12_+_25205666 0.100 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr6_-_127840021 0.099 ENST00000465909.2
SOGA3
SOGA family member 3
chr9_-_88896977 0.099 ENST00000311534.6
ISCA1
iron-sulfur cluster assembly 1
chr5_+_140201183 0.098 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
PCDHA5


protocadherin alpha 5


chr7_-_112727774 0.098 ENST00000297146.3
ENST00000501255.2
GPR85

G protein-coupled receptor 85

chr5_-_146435694 0.096 ENST00000356826.3
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr10_-_32667660 0.096 ENST00000375110.2
EPC1
enhancer of polycomb homolog 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 0.7 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162)
0.2 0.6 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.2 0.6 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 1.0 GO:0070842 aggresome assembly(GO:0070842)
0.2 0.5 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.6 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.4 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.5 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.4 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.4 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 1.8 GO:0046541 saliva secretion(GO:0046541)
0.1 0.3 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.3 GO:0034239 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.1 2.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.7 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 0.4 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.5 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.7 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.8 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 1.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.2 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.2 GO:0010157 response to chlorate(GO:0010157)
0.1 0.2 GO:2000974 auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.3 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.9 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0070662 mast cell proliferation(GO:0070662)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.9 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.6 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.3 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.4 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.1 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.0 0.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.2 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.2 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.3 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.3 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 3.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 0.1 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.4 GO:0030220 platelet formation(GO:0030220)
0.0 1.7 GO:0001942 hair follicle development(GO:0001942)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0048514 angiogenesis(GO:0001525) blood vessel morphogenesis(GO:0048514)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0045786 negative regulation of cell cycle(GO:0045786)
0.0 0.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.6 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.5 GO:0043194 axon initial segment(GO:0043194)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.7 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0046848 hydroxyapatite binding(GO:0046848)
0.2 1.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 0.5 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.6 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 1.8 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.7 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.2 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.7 GO:0035198 miRNA binding(GO:0035198)
0.0 0.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.0 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 1.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.4 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME_SIGNALING_BY_SCF_KIT Genes involved in Signaling by SCF-KIT
0.0 0.5 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.6 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.3 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.2 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones