Motif ID: STAT5A

Z-value: 0.851


Transcription factors associated with STAT5A:

Gene SymbolEntrez IDGene Name
STAT5A ENSG00000126561.12 STAT5A

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
STAT5Ahg19_v2_chr17_+_40440481_404405610.735.4e-05Click!


Activity profile for motif STAT5A.

activity profile for motif STAT5A


Sorted Z-values histogram for motif STAT5A

Sorted Z-values for motif STAT5A



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT5A

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_142829162 7.266 ENST00000291009.3
PIP
prolactin-induced protein
chr9_-_34397800 3.796 ENST00000297623.2
C9orf24
chromosome 9 open reading frame 24
chr19_-_55672037 3.072 ENST00000588076.1
DNAAF3
dynein, axonemal, assembly factor 3
chr17_+_9479944 2.454 ENST00000396219.3
ENST00000352665.5
WDR16

WD repeat domain 16

chr6_+_32407619 2.380 ENST00000395388.2
ENST00000374982.5
HLA-DRA

major histocompatibility complex, class II, DR alpha

chr11_+_73358594 2.309 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1


pleckstrin homology domain containing, family B (evectins) member 1


chr7_+_105603683 2.140 ENST00000317716.9
CDHR3
cadherin-related family member 3
chr1_+_47264711 2.128 ENST00000371923.4
ENST00000271153.4
ENST00000371919.4
CYP4B1


cytochrome P450, family 4, subfamily B, polypeptide 1


chr3_-_148939835 2.126 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr9_+_124922171 2.114 ENST00000373764.3
ENST00000536616.1
MORN5

MORN repeat containing 5

chr16_+_19421803 2.053 ENST00000541464.1
TMC5
transmembrane channel-like 5
chr12_-_15082050 1.947 ENST00000540097.1
ERP27
endoplasmic reticulum protein 27
chr14_+_96949319 1.853 ENST00000554706.1
AK7
adenylate kinase 7
chr14_-_21270561 1.825 ENST00000412779.2
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr11_+_27062860 1.797 ENST00000528583.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr21_-_35883613 1.782 ENST00000337385.3
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr11_+_111385497 1.679 ENST00000375618.4
ENST00000529167.1
ENST00000332814.6
C11orf88


chromosome 11 open reading frame 88


chr15_-_56757329 1.657 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr1_+_78956651 1.645 ENST00000370757.3
ENST00000370756.3
PTGFR

prostaglandin F receptor (FP)

chr2_-_28113217 1.637 ENST00000444339.2
RBKS
ribokinase
chrY_+_22737604 1.608 ENST00000361365.2
EIF1AY
eukaryotic translation initiation factor 1A, Y-linked
chr7_+_105603657 1.545 ENST00000542731.1
ENST00000343407.5
CDHR3

cadherin-related family member 3

chr9_+_124926856 1.535 ENST00000418632.1
MORN5
MORN repeat containing 5
chr19_-_44860820 1.493 ENST00000354340.4
ENST00000337401.4
ENST00000587909.1
ZNF112


zinc finger protein 112


chr17_+_41158742 1.485 ENST00000415816.2
ENST00000438323.2
IFI35

interferon-induced protein 35

chr13_+_24144509 1.468 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr2_-_238499303 1.463 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr7_-_138347897 1.452 ENST00000288513.5
SVOPL
SVOP-like
chr16_+_19422035 1.440 ENST00000381414.4
ENST00000396229.2
TMC5

transmembrane channel-like 5

chrY_+_15016725 1.411 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr18_-_24722995 1.401 ENST00000581714.1
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr11_+_1244288 1.400 ENST00000529681.1
ENST00000447027.1
MUC5B

mucin 5B, oligomeric mucus/gel-forming

chr14_-_107078851 1.369 ENST00000390628.2
IGHV1-58
immunoglobulin heavy variable 1-58
chr15_-_93616340 1.361 ENST00000557420.1
ENST00000542321.2
RGMA

repulsive guidance molecule family member a

chr8_-_128960591 1.322 ENST00000539634.1
TMEM75
transmembrane protein 75
chr12_+_20963647 1.291 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr11_+_27062502 1.287 ENST00000263182.3
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr3_+_58223228 1.284 ENST00000478253.1
ENST00000295962.4
ABHD6

abhydrolase domain containing 6

chr17_+_17876127 1.279 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
LRRC48









leucine rich repeat containing 48









chr5_+_140227048 1.265 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr6_+_32605195 1.256 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr16_-_75590114 1.225 ENST00000568377.1
ENST00000565067.1
ENST00000258173.6
TMEM231


transmembrane protein 231


chr4_-_100356291 1.217 ENST00000476959.1
ENST00000482593.1
ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

chr10_-_28287968 1.203 ENST00000305242.5
ARMC4
armadillo repeat containing 4
chr1_-_48937838 1.189 ENST00000371847.3
SPATA6
spermatogenesis associated 6
chr3_+_187086120 1.189 ENST00000259030.2
RTP4
receptor (chemosensory) transporter protein 4
chr6_+_33048222 1.188 ENST00000428835.1
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr20_+_58571419 1.170 ENST00000244049.3
ENST00000350849.6
ENST00000456106.1
CDH26


cadherin 26


chr9_+_74764340 1.167 ENST00000376986.1
ENST00000358399.3
GDA

guanine deaminase

chr11_-_111175739 1.160 ENST00000532918.1
COLCA1
colorectal cancer associated 1
chr2_-_220108309 1.158 ENST00000409640.1
GLB1L
galactosidase, beta 1-like
chr4_-_38806404 1.155 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
TLR1


toll-like receptor 1


chr17_+_4981535 1.152 ENST00000318833.3
ZFP3
ZFP3 zinc finger protein
chr5_-_13944652 1.152 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr22_-_31503490 1.142 ENST00000400299.2
SELM
Selenoprotein M
chr11_+_36616355 1.136 ENST00000532470.2
C11orf74
chromosome 11 open reading frame 74
chr19_+_35168567 1.129 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
ZNF302





zinc finger protein 302





chrY_+_22737678 1.128 ENST00000382772.3
EIF1AY
eukaryotic translation initiation factor 1A, Y-linked
chr21_-_35883541 1.121 ENST00000399284.1
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr15_+_50474385 1.109 ENST00000267842.5
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
chr22_+_23487513 1.106 ENST00000263116.2
ENST00000341989.4
RAB36

RAB36, member RAS oncogene family

chr9_-_89562104 1.103 ENST00000298743.7
GAS1
growth arrest-specific 1
chr19_+_44669280 1.082 ENST00000590089.1
ENST00000454662.2
ZNF226

zinc finger protein 226

chr15_+_50474412 1.082 ENST00000380902.4
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
chr4_+_75858290 1.079 ENST00000513238.1
PARM1
prostate androgen-regulated mucin-like protein 1
chr12_+_20963632 1.073 ENST00000540853.1
ENST00000261196.2
SLCO1B3

solute carrier organic anion transporter family, member 1B3

chr17_-_63557759 1.058 ENST00000307078.5
AXIN2
axin 2
chr13_-_20077417 1.029 ENST00000382978.1
ENST00000400230.2
ENST00000255310.6
TPTE2


transmembrane phosphoinositide 3-phosphatase and tensin homolog 2


chr17_+_40440481 1.029 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A



signal transducer and activator of transcription 5A



chr8_+_86157699 1.025 ENST00000321764.3
CA13
carbonic anhydrase XIII
chr10_-_116444371 1.016 ENST00000533213.2
ENST00000369252.4
ABLIM1

actin binding LIM protein 1

chr5_-_41213607 0.987 ENST00000337836.5
ENST00000433294.1
C6

complement component 6

chr11_+_46299199 0.966 ENST00000529193.1
ENST00000288400.3
CREB3L1

cAMP responsive element binding protein 3-like 1

chr16_-_19897455 0.963 ENST00000568214.1
ENST00000569479.1
GPRC5B

G protein-coupled receptor, family C, group 5, member B

chr16_+_616995 0.953 ENST00000293874.2
ENST00000409527.2
ENST00000424439.2
ENST00000540585.1
PIGQ

NHLRC4

phosphatidylinositol glycan anchor biosynthesis, class Q

NHL repeat containing 4

chr19_+_35168633 0.946 ENST00000505365.2
ZNF302
zinc finger protein 302
chr1_+_20512568 0.938 ENST00000375099.3
UBXN10
UBX domain protein 10
chr3_-_114866084 0.932 ENST00000357258.3
ZBTB20
zinc finger and BTB domain containing 20
chr3_-_107941209 0.925 ENST00000492106.1
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr16_+_23765948 0.923 ENST00000300113.2
CHP2
calcineurin-like EF-hand protein 2
chr19_+_11457232 0.913 ENST00000587531.1
CCDC159
coiled-coil domain containing 159
chr15_-_78526855 0.905 ENST00000541759.1
ENST00000558130.1
ACSBG1

acyl-CoA synthetase bubblegum family member 1

chr2_-_38303218 0.901 ENST00000407341.1
ENST00000260630.3
CYP1B1

cytochrome P450, family 1, subfamily B, polypeptide 1

chr7_+_150382781 0.900 ENST00000223293.5
ENST00000474605.1
GIMAP2

GTPase, IMAP family member 2

chr14_-_92414055 0.894 ENST00000342058.4
FBLN5
fibulin 5
chr17_+_12692774 0.877 ENST00000379672.5
ENST00000340825.3
ARHGAP44

Rho GTPase activating protein 44

chr2_-_238499337 0.873 ENST00000411462.1
ENST00000409822.1
RAB17

RAB17, member RAS oncogene family

chr5_-_118324200 0.871 ENST00000515439.3
ENST00000510708.1
DTWD2

DTW domain containing 2

chr2_+_163200848 0.860 ENST00000233612.4
GCA
grancalcin, EF-hand calcium binding protein
chr2_+_149894968 0.857 ENST00000409642.3
LYPD6B
LY6/PLAUR domain containing 6B
chr10_+_95848824 0.857 ENST00000371385.3
ENST00000371375.1
PLCE1

phospholipase C, epsilon 1

chr1_+_87794150 0.856 ENST00000370544.5
LMO4
LIM domain only 4
chr7_-_95225768 0.839 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr11_-_34533257 0.837 ENST00000312319.2
ELF5
E74-like factor 5 (ets domain transcription factor)
chr3_+_97483366 0.835 ENST00000463745.1
ENST00000462412.1
ARL6

ADP-ribosylation factor-like 6

chr2_+_149895207 0.835 ENST00000409876.1
LYPD6B
LY6/PLAUR domain containing 6B
chr10_+_7745232 0.828 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr5_-_180288248 0.827 ENST00000512132.1
ENST00000506439.1
ENST00000502412.1
ENST00000359141.6
ZFP62



ZFP62 zinc finger protein



chr1_-_94374946 0.821 ENST00000370238.3
GCLM
glutamate-cysteine ligase, modifier subunit
chrX_+_55478538 0.802 ENST00000342972.1
MAGEH1
melanoma antigen family H, 1
chr1_-_20446020 0.799 ENST00000375105.3
PLA2G2D
phospholipase A2, group IID
chr2_-_238499131 0.796 ENST00000538644.1
RAB17
RAB17, member RAS oncogene family
chr11_-_26593649 0.792 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chrY_+_15016013 0.791 ENST00000360160.4
ENST00000454054.1
DDX3Y

DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked

chr10_+_70939983 0.791 ENST00000359655.4
ENST00000422378.1
SUPV3L1

suppressor of var1, 3-like 1 (S. cerevisiae)

chr4_+_130017268 0.786 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
C4orf33


chromosome 4 open reading frame 33


chr14_-_92333873 0.785 ENST00000435962.2
TC2N
tandem C2 domains, nuclear
chr10_+_95753714 0.785 ENST00000260766.3
PLCE1
phospholipase C, epsilon 1
chr10_-_50122277 0.779 ENST00000374160.3
LRRC18
leucine rich repeat containing 18
chr4_+_9172135 0.777 ENST00000512047.1
FAM90A26
family with sequence similarity 90, member A26
chr3_+_97483572 0.773 ENST00000335979.2
ENST00000394206.1
ARL6

ADP-ribosylation factor-like 6

chr19_+_5720666 0.755 ENST00000381624.3
ENST00000381614.2
CATSPERD

catsper channel auxiliary subunit delta

chr3_-_165555200 0.753 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE



butyrylcholinesterase



chr1_+_46640750 0.747 ENST00000372003.1
TSPAN1
tetraspanin 1
chr3_+_132036207 0.746 ENST00000336375.5
ENST00000495911.1
ACPP

acid phosphatase, prostate

chr8_-_133772794 0.745 ENST00000519187.1
ENST00000523829.1
ENST00000356838.3
ENST00000377901.4
ENST00000519304.1
TMEM71




transmembrane protein 71




chr2_+_149804382 0.744 ENST00000397413.1
KIF5C
kinesin family member 5C
chr11_+_36616044 0.737 ENST00000334307.5
ENST00000531554.1
ENST00000347206.4
ENST00000534635.1
ENST00000446510.2
ENST00000530697.1
ENST00000527108.1
C11orf74






chromosome 11 open reading frame 74






chr3_-_120365866 0.718 ENST00000475447.2
HGD
homogentisate 1,2-dioxygenase
chr14_-_25519095 0.711 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
STXBP6



syntaxin binding protein 6 (amisyn)



chr16_-_1661988 0.708 ENST00000426508.2
IFT140
intraflagellar transport 140 homolog (Chlamydomonas)
chr19_+_35225060 0.708 ENST00000599244.1
ENST00000392232.3
ZNF181

zinc finger protein 181

chr11_-_105892937 0.697 ENST00000301919.4
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
MSANTD4



Myb/SANT-like DNA-binding domain containing 4 with coiled-coils



chr11_-_26593677 0.696 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr9_+_108456800 0.696 ENST00000434214.1
ENST00000374692.3
TMEM38B

transmembrane protein 38B

chr17_+_32683456 0.685 ENST00000225844.2
CCL13
chemokine (C-C motif) ligand 13
chr7_-_69062391 0.682 ENST00000436600.2
RP5-942I16.1
RP5-942I16.1
chr9_+_100000717 0.682 ENST00000375205.2
ENST00000357054.1
ENST00000395220.1
ENST00000375202.2
ENST00000411667.2
CCDC180




coiled-coil domain containing 180




chr6_-_83775489 0.679 ENST00000369747.3
UBE3D
ubiquitin protein ligase E3D
chr1_-_226129189 0.677 ENST00000366820.5
LEFTY2
left-right determination factor 2
chr1_+_201979645 0.662 ENST00000367284.5
ENST00000367283.3
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr5_-_42812143 0.661 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr13_+_24144796 0.661 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr1_-_48937821 0.660 ENST00000396199.3
SPATA6
spermatogenesis associated 6
chr9_-_15510989 0.659 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
PSIP1



PC4 and SFRS1 interacting protein 1



chr3_-_137834436 0.654 ENST00000327532.2
ENST00000467030.1
DZIP1L

DAZ interacting zinc finger protein 1-like

chr1_-_115632035 0.653 ENST00000433172.1
ENST00000369514.2
ENST00000369516.2
ENST00000369515.2
TSPAN2



tetraspanin 2



chr1_+_244515930 0.652 ENST00000366537.1
ENST00000308105.4
C1orf100

chromosome 1 open reading frame 100

chr6_+_133562744 0.652 ENST00000525849.1
EYA4
eyes absent homolog 4 (Drosophila)
chr3_-_107941230 0.651 ENST00000264538.3
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr12_+_133657461 0.645 ENST00000412146.2
ENST00000544426.1
ENST00000440984.2
ENST00000319849.3
ENST00000440550.2
ZNF140




zinc finger protein 140




chr8_-_27468842 0.644 ENST00000523500.1
CLU
clusterin
chr11_+_63137251 0.642 ENST00000310969.4
ENST00000279178.3
SLC22A9

solute carrier family 22 (organic anion transporter), member 9

chr14_+_75988851 0.631 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr22_+_39052632 0.630 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1



chibby homolog 1 (Drosophila)



chr14_+_74004051 0.627 ENST00000557556.1
ACOT1
acyl-CoA thioesterase 1
chr17_-_61512545 0.625 ENST00000585153.1
CYB561
cytochrome b561
chr11_-_49230144 0.623 ENST00000343844.4
FOLH1
folate hydrolase (prostate-specific membrane antigen) 1
chr1_+_114471809 0.623 ENST00000426820.2
HIPK1
homeodomain interacting protein kinase 1
chr2_-_79315112 0.621 ENST00000305089.3
REG1B
regenerating islet-derived 1 beta
chr7_+_12610307 0.614 ENST00000297029.5
SCIN
scinderin
chr11_+_66276550 0.614 ENST00000419755.3
CTD-3074O7.11
Bardet-Biedl syndrome 1 protein
chrX_+_24711997 0.613 ENST00000379068.3
ENST00000379059.3
POLA1

polymerase (DNA directed), alpha 1, catalytic subunit

chr15_+_67547163 0.613 ENST00000335894.4
IQCH
IQ motif containing H
chr10_+_94594351 0.604 ENST00000371552.4
EXOC6
exocyst complex component 6
chr1_-_159046617 0.601 ENST00000368130.4
AIM2
absent in melanoma 2
chr6_-_3195981 0.600 ENST00000425384.2
ENST00000435043.2
RP1-40E16.9

RP1-40E16.9

chr5_-_179499108 0.598 ENST00000521389.1
RNF130
ring finger protein 130
chr11_-_49230184 0.595 ENST00000340334.7
ENST00000256999.2
FOLH1

folate hydrolase (prostate-specific membrane antigen) 1

chr9_-_97402531 0.590 ENST00000415431.1
FBP1
fructose-1,6-bisphosphatase 1
chr5_-_70363428 0.589 ENST00000274400.5
ENST00000425596.2
ENST00000521602.2
ENST00000330280.7
ENST00000517900.1
GTF2H2




general transcription factor IIH, polypeptide 2, 44kDa




chr15_+_65843130 0.584 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr2_+_32853093 0.582 ENST00000448773.1
ENST00000317907.4
TTC27

tetratricopeptide repeat domain 27

chr19_-_460996 0.581 ENST00000264554.6
SHC2
SHC (Src homology 2 domain containing) transforming protein 2
chr4_-_23735183 0.579 ENST00000507666.1
RP11-380P13.2
RP11-380P13.2
chr1_-_157108266 0.578 ENST00000326786.4
ETV3
ets variant 3
chr3_-_155462808 0.577 ENST00000460012.1
PLCH1
phospholipase C, eta 1
chr11_+_7618413 0.577 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr20_-_18447667 0.576 ENST00000262547.5
ENST00000329494.5
ENST00000357236.4
DZANK1


double zinc ribbon and ankyrin repeat domains 1


chr1_-_48937682 0.572 ENST00000371843.3
SPATA6
spermatogenesis associated 6
chr14_-_36983034 0.569 ENST00000518529.2
SFTA3
surfactant associated 3
chr16_-_18441131 0.569 ENST00000339303.5
NPIPA8
nuclear pore complex interacting protein family, member A8
chr10_+_6625605 0.568 ENST00000414894.1
ENST00000449648.1
PRKCQ-AS1

PRKCQ antisense RNA 1

chr1_-_11107280 0.566 ENST00000400897.3
ENST00000400898.3
MASP2

mannan-binding lectin serine peptidase 2

chr11_-_49230084 0.565 ENST00000356696.3
FOLH1
folate hydrolase (prostate-specific membrane antigen) 1
chr15_-_83680325 0.564 ENST00000508990.2
ENST00000510873.2
ENST00000538348.2
ENST00000451195.3
ENST00000513601.2
ENST00000304177.5
ENST00000565712.1
C15orf40






chromosome 15 open reading frame 40






chr3_-_160117301 0.561 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
IFT80



intraflagellar transport 80 homolog (Chlamydomonas)



chr1_-_226129083 0.561 ENST00000420304.2
LEFTY2
left-right determination factor 2
chr19_-_44809121 0.558 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
ZNF235



zinc finger protein 235



chr17_+_21030260 0.554 ENST00000579303.1
DHRS7B
dehydrogenase/reductase (SDR family) member 7B
chr19_+_58193388 0.550 ENST00000596085.1
ENST00000594684.1
ZNF551
AC003006.7
zinc finger protein 551
Uncharacterized protein
chr18_+_61575200 0.550 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr5_+_68856035 0.549 ENST00000512736.1
ENST00000510979.1
ENST00000514162.1
ENST00000380729.3
ENST00000508344.2
GTF2H2C




general transcription factor IIH, polypeptide 2C




chr16_-_5115913 0.547 ENST00000474471.3
C16orf89
chromosome 16 open reading frame 89
chr15_+_74610894 0.547 ENST00000558821.1
ENST00000268082.4
CCDC33

coiled-coil domain containing 33

chr8_-_27468945 0.546 ENST00000405140.3
CLU
clusterin
chr5_-_179499086 0.545 ENST00000261947.4
RNF130
ring finger protein 130
chr21_-_37451680 0.542 ENST00000399201.1
SETD4
SET domain containing 4
chr22_-_36018569 0.541 ENST00000419229.1
ENST00000406324.1
MB

myoglobin

chr11_-_49229924 0.541 ENST00000533034.1
FOLH1
folate hydrolase (prostate-specific membrane antigen) 1
chr12_+_32112340 0.539 ENST00000540924.1
ENST00000312561.4
KIAA1551

KIAA1551

chr16_+_640055 0.538 ENST00000568586.1
ENST00000538492.1
ENST00000248139.3
RAB40C


RAB40C, member RAS oncogene family


chr9_+_86238016 0.536 ENST00000530832.1
ENST00000405990.3
ENST00000376417.4
ENST00000376419.4
IDNK



idnK, gluconokinase homolog (E. coli)



chr7_+_117120017 0.536 ENST00000003084.6
ENST00000454343.1
CFTR

cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)

chr21_+_42792442 0.536 ENST00000398600.2
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr16_-_68406161 0.535 ENST00000568373.1
ENST00000563226.1
SMPD3

sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)

chrX_-_48776292 0.532 ENST00000376509.4
PIM2
pim-2 oncogene
chr6_+_32605134 0.532 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
HLA-DQA1


major histocompatibility complex, class II, DQ alpha 1


chr14_+_21156915 0.531 ENST00000397990.4
ENST00000555597.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr3_+_149191723 0.531 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.6 2.4 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.5 2.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.5 1.6 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.4 2.8 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.4 1.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.4 1.6 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.4 1.1 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.4 2.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.3 1.0 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.3 2.3 GO:0071461 cellular response to redox state(GO:0071461)
0.3 2.1 GO:0018879 biphenyl metabolic process(GO:0018879)
0.3 0.9 GO:0014016 neuroblast differentiation(GO:0014016)
0.3 1.7 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.3 0.8 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.3 1.3 GO:0019303 D-ribose catabolic process(GO:0019303)
0.3 1.0 GO:0000255 allantoin metabolic process(GO:0000255)
0.3 1.0 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.2 1.0 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.2 1.0 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.2 0.9 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.2 0.9 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.2 0.9 GO:0098886 modification of dendritic spine(GO:0098886)
0.2 2.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 6.9 GO:0044458 motile cilium assembly(GO:0044458)
0.2 7.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 1.0 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.2 1.2 GO:0046098 guanine metabolic process(GO:0046098)
0.2 0.6 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.2 0.9 GO:0072313 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.2 1.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 0.9 GO:0034486 vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741)
0.2 0.5 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.2 0.5 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.2 0.7 GO:0090264 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) response to high density lipoprotein particle(GO:0055099) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
0.2 2.9 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315) negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.2 2.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 1.5 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.2 0.5 GO:1902161 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.2 0.8 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.2 0.6 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.8 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.4 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.3 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.4 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.7 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 1.0 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 1.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 0.4 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 1.0 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.4 GO:0070428 negative regulation of interleukin-23 production(GO:0032707) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.1 0.3 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.1 0.3 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.3 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.3 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1 1.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 2.0 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.3 GO:0090024 complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1 0.3 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.1 0.4 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.3 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.1 0.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 1.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.6 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 1.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 2.3 GO:0006825 copper ion transport(GO:0006825)
0.1 0.8 GO:1990403 embryonic brain development(GO:1990403)
0.1 1.4 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.2 GO:1902996 regulation of neurofibrillary tangle assembly(GO:1902996)
0.1 0.3 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 0.2 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.0 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.4 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 0.1 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.1 0.1 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1 0.3 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.6 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.7 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.3 GO:0001555 oocyte growth(GO:0001555)
0.1 0.9 GO:0015747 urate transport(GO:0015747)
0.1 0.9 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 0.2 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 0.2 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.1 0.2 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.1 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.1 0.2 GO:1990641 cellular response to bile acid(GO:1903413) response to iron ion starvation(GO:1990641)
0.1 0.7 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.6 GO:0070269 pyroptosis(GO:0070269)
0.1 0.2 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.1 0.4 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.1 2.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 0.8 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1 0.2 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 0.3 GO:0071504 cellular response to heparin(GO:0071504)
0.1 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.8 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.3 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.1 0.1 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.1 0.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.2 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 0.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.2 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 0.3 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.4 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.1 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.6 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.8 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 1.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.0 0.1 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.5 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.3 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.4 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.4 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 1.0 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0030473 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:0019075 virus maturation(GO:0019075)
0.0 0.2 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.0 0.3 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.2 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.6 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.3 GO:0015705 iodide transport(GO:0015705)
0.0 1.7 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.0 0.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.2 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.3 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.6 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 1.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0002118 aggressive behavior(GO:0002118)
0.0 1.4 GO:0043030 regulation of macrophage activation(GO:0043030)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.6 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.3 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.1 GO:0090427 monocyte extravasation(GO:0035696) regulation of fertilization(GO:0080154) activation of meiosis(GO:0090427) regulation of monocyte extravasation(GO:2000437)
0.0 2.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 2.5 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.5 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.0 0.4 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.6 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.1 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.3 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.3 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 1.8 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.6 GO:0002320 lymphoid progenitor cell differentiation(GO:0002320)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.2 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.2 GO:0001554 luteolysis(GO:0001554)
0.0 0.3 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.6 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.6 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 5.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.3 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.4 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 3.1 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.5 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.4 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 1.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.5 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.2 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.0 0.1 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 1.0 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 1.3 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 1.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.2 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.6 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.0 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.5 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.4 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.3 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.2 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.1 GO:0002418 immune response to tumor cell(GO:0002418)
0.0 1.1 GO:0007602 phototransduction(GO:0007602)
0.0 0.2 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 1.5 GO:0001942 hair follicle development(GO:0001942)
0.0 0.1 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 0.1 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.6 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.3 GO:0030220 platelet formation(GO:0030220)
0.0 0.3 GO:0051168 nuclear export(GO:0051168)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.0 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.0 GO:0036302 atrioventricular canal development(GO:0036302)
0.0 0.6 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.3 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 2.9 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.1 GO:0019835 cytolysis(GO:0019835)
0.0 0.3 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.0 GO:0014744 positive regulation of muscle adaptation(GO:0014744)
0.0 0.7 GO:1903901 negative regulation of viral process(GO:0048525) negative regulation of viral life cycle(GO:1903901)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.2 GO:0044030 regulation of DNA methylation(GO:0044030)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0097224 sperm connecting piece(GO:0097224)
0.4 0.9 GO:0005667 transcription factor complex(GO:0005667)
0.4 1.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.3 1.6 GO:0005879 axonemal microtubule(GO:0005879)
0.3 0.9 GO:0005608 laminin-3 complex(GO:0005608)
0.3 6.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 0.8 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.2 0.6 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.2 0.6 GO:0031251 PAN complex(GO:0031251)
0.1 0.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.9 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 1.1 GO:0005579 membrane attack complex(GO:0005579)
0.1 3.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.5 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 1.2 GO:0036157 outer dynein arm(GO:0036157)
0.1 1.7 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 0.5 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.9 GO:0071953 elastic fiber(GO:0071953)
0.1 0.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.5 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 1.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 1.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 2.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.5 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 1.2 GO:0036038 MKS complex(GO:0036038)
0.1 0.7 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.8 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.2 GO:0036398 TCR signalosome(GO:0036398)
0.1 0.6 GO:0001739 sex chromatin(GO:0001739)
0.1 0.3 GO:1990357 terminal web(GO:1990357)
0.1 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.4 GO:0036128 CatSper complex(GO:0036128)
0.0 0.9 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.5 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.5 GO:0000145 exocyst(GO:0000145)
0.0 3.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.0 GO:0042599 lamellar body(GO:0042599)
0.0 0.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0000785 chromatin(GO:0000785)
0.0 0.2 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 1.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 1.2 GO:0097546 ciliary base(GO:0097546)
0.0 0.3 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 1.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.5 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.2 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.0 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 2.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.5 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 2.2 GO:0072562 blood microparticle(GO:0072562)
0.0 0.6 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 1.0 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.3 GO:0042629 mast cell granule(GO:0042629)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.6 2.3 GO:1904493 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.5 1.6 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.4 7.1 GO:0019864 IgG binding(GO:0019864)
0.4 5.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 2.4 GO:0004522 ribonuclease A activity(GO:0004522)
0.3 1.0 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.3 1.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.3 1.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.3 0.8 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.3 1.9 GO:0004127 cytidylate kinase activity(GO:0004127)
0.3 1.0 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.3 1.0 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2 1.4 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 0.9 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 3.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 0.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 2.7 GO:0031433 telethonin binding(GO:0031433)
0.2 1.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 1.2 GO:0035276 ethanol binding(GO:0035276)
0.2 0.6 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.2 0.8 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.2 2.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 2.4 GO:0032027 myosin light chain binding(GO:0032027)
0.2 0.5 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 0.6 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 2.0 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.6 GO:0001855 complement component C4b binding(GO:0001855)
0.1 0.4 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 2.9 GO:0070330 aromatase activity(GO:0070330)
0.1 0.4 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.6 GO:0004905 type I interferon receptor activity(GO:0004905)
0.1 1.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.3 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.1 0.4 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.3 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 1.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 1.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.6 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.9 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 1.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.3 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 1.7 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.0 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.0 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.5 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.3 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 1.0 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.6 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.3 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.3 GO:0036033 mediator complex binding(GO:0036033)
0.1 1.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.1 0.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.4 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.4 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 0.2 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 0.4 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.8 GO:0097100 supercoiled DNA binding(GO:0097100)
0.1 0.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.2 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.2 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 0.2 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 2.2 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 1.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.8 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.1 0.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.3 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.2 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 1.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.5 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 1.0 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 1.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 3.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 1.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.4 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 1.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 2.9 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.3 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.5 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.4 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.3 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.9 GO:0030332 cyclin binding(GO:0030332)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0034061 DNA polymerase activity(GO:0034061)
0.0 0.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.0 GO:0052726 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.0 0.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 1.0 GO:0016279 protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 2.3 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.9 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 3.6 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.1 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.4 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.5 PID_BMP_PATHWAY BMP receptor signaling
0.0 4.7 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.6 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 1.0 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 0.5 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.6 REACTOME_PROSTANOID_LIGAND_RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.9 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.1 2.7 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 2.4 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.6 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.1 1.2 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 0.7 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.1 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.9 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.1 0.8 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.8 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.8 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.0 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 0.6 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.0 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.0 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.1 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.1 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.5 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.0 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.0 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.2 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.8 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.5 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.6 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 2.1 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME_SHC_MEDIATED_SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.6 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.8 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.6 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.0 0.9 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.6 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.0 0.3 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.6 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.8 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.9 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 1.1 REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.2 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.3 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin