Motif ID: T

Z-value: 0.566


Transcription factors associated with T:

Gene SymbolEntrez IDGene Name
T ENSG00000164458.5 T

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Thg19_v2_chr6_-_166582107_1665821880.154.7e-01Click!


Activity profile for motif T.

activity profile for motif T


Sorted Z-values histogram for motif T

Sorted Z-values for motif T



Network of associatons between targets according to the STRING database.



First level regulatory network of T

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_153029980 1.750 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr14_+_75746781 1.542 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr10_+_94833642 1.372 ENST00000224356.4
ENST00000394139.1
CYP26A1

cytochrome P450, family 26, subfamily A, polypeptide 1

chr12_-_52845910 1.323 ENST00000252252.3
KRT6B
keratin 6B
chr1_-_153066998 1.230 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr21_+_30502806 1.189 ENST00000399928.1
ENST00000399926.1
MAP3K7CL

MAP3K7 C-terminal like

chr9_+_36572851 0.981 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK







maternal embryonic leucine zipper kinase







chr2_-_216003127 0.864 ENST00000412081.1
ENST00000272895.7
ABCA12

ATP-binding cassette, sub-family A (ABC1), member 12

chr12_+_22778291 0.843 ENST00000545979.1
ETNK1
ethanolamine kinase 1
chr12_-_6961050 0.817 ENST00000538862.2
CDCA3
cell division cycle associated 3
chr7_+_134576317 0.771 ENST00000424922.1
ENST00000495522.1
CALD1

caldesmon 1

chr12_-_6960407 0.751 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
CDCA3



cell division cycle associated 3



chr19_-_44174330 0.726 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr12_-_69326940 0.621 ENST00000549781.1
ENST00000548262.1
ENST00000551568.1
ENST00000548954.1
CPM



carboxypeptidase M



chr19_-_44174305 0.608 ENST00000601723.1
ENST00000339082.3
PLAUR

plasminogen activator, urokinase receptor

chr2_-_85636928 0.607 ENST00000449030.1
CAPG
capping protein (actin filament), gelsolin-like
chr4_-_73434498 0.599 ENST00000286657.4
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr9_+_40028620 0.597 ENST00000426179.1
AL353791.1
AL353791.1
chr1_-_24126023 0.593 ENST00000429356.1
GALE
UDP-galactose-4-epimerase
chr20_+_44637526 0.587 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr7_-_76255444 0.580 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr19_+_7030589 0.572 ENST00000329753.5
MBD3L5
methyl-CpG binding domain protein 3-like 5
chr5_+_54320078 0.568 ENST00000231009.2
GZMK
granzyme K (granzyme 3; tryptase II)
chr19_+_7049332 0.539 ENST00000381393.3
MBD3L2
methyl-CpG binding domain protein 3-like 2
chr7_-_28220354 0.538 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr9_+_139553306 0.533 ENST00000371699.1
EGFL7
EGF-like-domain, multiple 7
chr12_-_52867569 0.515 ENST00000252250.6
KRT6C
keratin 6C
chr11_+_133938820 0.511 ENST00000299106.4
ENST00000529443.2
JAM3

junctional adhesion molecule 3

chr1_-_204135450 0.481 ENST00000272190.8
ENST00000367195.2
REN

renin

chr14_+_96722539 0.480 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr11_+_133938955 0.479 ENST00000534549.1
ENST00000441717.3
JAM3

junctional adhesion molecule 3

chr20_+_32951070 0.475 ENST00000535650.1
ENST00000262650.6
ITCH

itchy E3 ubiquitin protein ligase

chr19_+_11546093 0.473 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr19_+_11546440 0.457 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
PRKCSH





protein kinase C substrate 80K-H





chr2_+_234601512 0.454 ENST00000305139.6
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr19_+_11546153 0.450 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH


protein kinase C substrate 80K-H


chr2_-_208030647 0.446 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr7_-_38370536 0.439 ENST00000390343.2
TRGV8
T cell receptor gamma variable 8
chr21_-_45078019 0.420 ENST00000542962.1
HSF2BP
heat shock transcription factor 2 binding protein
chr17_+_26662597 0.413 ENST00000544907.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr17_-_74497432 0.412 ENST00000590288.1
ENST00000313080.4
ENST00000592123.1
ENST00000591255.1
ENST00000585989.1
ENST00000591697.1
ENST00000389760.4
RHBDF2






rhomboid 5 homolog 2 (Drosophila)






chr21_-_31869451 0.410 ENST00000334058.2
KRTAP19-4
keratin associated protein 19-4
chr3_-_57678772 0.403 ENST00000311128.5
DENND6A
DENN/MADD domain containing 6A
chr1_-_150980828 0.391 ENST00000361936.5
ENST00000361738.6
FAM63A

family with sequence similarity 63, member A

chr17_+_17942684 0.390 ENST00000376345.3
GID4
GID complex subunit 4
chr5_+_14664762 0.387 ENST00000284274.4
FAM105B
family with sequence similarity 105, member B
chr20_-_1309809 0.374 ENST00000360779.3
SDCBP2
syndecan binding protein (syntenin) 2
chr10_-_5060147 0.373 ENST00000604507.1
AKR1C2
aldo-keto reductase family 1, member C2
chr1_-_24126051 0.368 ENST00000445705.1
GALE
UDP-galactose-4-epimerase
chr2_-_27341966 0.360 ENST00000402394.1
ENST00000402550.1
ENST00000260595.5
CGREF1


cell growth regulator with EF-hand domain 1


chr16_+_69458537 0.359 ENST00000515314.1
ENST00000561792.1
ENST00000568237.1
CYB5B


cytochrome b5 type B (outer mitochondrial membrane)


chr11_-_85779971 0.342 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr1_-_156542328 0.333 ENST00000361170.2
IQGAP3
IQ motif containing GTPase activating protein 3
chr12_-_117318788 0.315 ENST00000550505.1
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr1_-_13052998 0.311 ENST00000436041.1
WI2-3308P17.2
Uncharacterized protein
chr19_-_17958771 0.305 ENST00000534444.1
JAK3
Janus kinase 3
chr3_+_102153859 0.300 ENST00000306176.1
ENST00000466937.1
ZPLD1

zona pellucida-like domain containing 1

chr10_-_76868931 0.297 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
DUSP13




dual specificity phosphatase 13




chr20_-_44298878 0.290 ENST00000324384.3
ENST00000356562.2
WFDC11

WAP four-disulfide core domain 11

chr9_-_14722715 0.290 ENST00000380911.3
CER1
cerberus 1, DAN family BMP antagonist
chr17_+_19281034 0.289 ENST00000308406.5
ENST00000299612.7
MAPK7

mitogen-activated protein kinase 7

chr10_+_5488564 0.287 ENST00000449083.1
ENST00000380359.3
NET1

neuroepithelial cell transforming 1

chr10_-_5060201 0.284 ENST00000407674.1
AKR1C2
aldo-keto reductase family 1, member C2
chr20_-_60942361 0.280 ENST00000252999.3
LAMA5
laminin, alpha 5
chr7_+_107220660 0.276 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
BCAP29




B-cell receptor-associated protein 29




chr16_+_67313412 0.270 ENST00000379344.3
ENST00000568621.1
ENST00000450733.1
ENST00000567938.1
PLEKHG4



pleckstrin homology domain containing, family G (with RhoGef domain) member 4



chr12_-_49351228 0.257 ENST00000541959.1
ENST00000447318.2
ARF3

ADP-ribosylation factor 3

chr11_+_120081475 0.250 ENST00000328965.4
OAF
OAF homolog (Drosophila)
chr10_-_23003460 0.249 ENST00000376573.4
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr6_+_29079668 0.244 ENST00000377169.1
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr19_-_10514184 0.241 ENST00000589629.1
ENST00000222005.2
CDC37

cell division cycle 37

chr17_+_57970469 0.235 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
RPS6KB1



ribosomal protein S6 kinase, 70kDa, polypeptide 1



chr17_+_34538310 0.234 ENST00000444414.1
ENST00000378350.4
ENST00000389068.5
ENST00000588929.1
ENST00000589079.1
ENST00000589336.1
ENST00000400702.4
ENST00000591167.1
ENST00000586598.1
ENST00000591637.1
ENST00000378352.4
ENST00000358756.5
CCL4L1











chemokine (C-C motif) ligand 4-like 1











chr1_+_78245303 0.229 ENST00000370791.3
ENST00000443751.2
FAM73A

family with sequence similarity 73, member A

chr22_+_19929130 0.226 ENST00000361682.6
ENST00000403184.1
ENST00000403710.1
ENST00000407537.1
COMT



catechol-O-methyltransferase



chrX_+_79591003 0.222 ENST00000538312.1
FAM46D
family with sequence similarity 46, member D
chr7_+_110731062 0.220 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3



leucine rich repeat neuronal 3



chr6_-_29324054 0.208 ENST00000543825.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr2_-_61245363 0.205 ENST00000316752.6
PUS10
pseudouridylate synthase 10
chr2_-_241737128 0.199 ENST00000404283.3
KIF1A
kinesin family member 1A
chr12_+_57610562 0.190 ENST00000349394.5
NXPH4
neurexophilin 4
chr20_+_32951041 0.187 ENST00000374864.4
ITCH
itchy E3 ubiquitin protein ligase
chrX_+_100353153 0.186 ENST00000423383.1
ENST00000218507.5
ENST00000403304.2
ENST00000435570.1
CENPI



centromere protein I



chr11_-_66112555 0.186 ENST00000425825.2
ENST00000359957.3
BRMS1

breast cancer metastasis suppressor 1

chr14_-_74025625 0.184 ENST00000553558.1
ENST00000563329.1
ENST00000334988.2
ENST00000560393.1
HEATR4



HEAT repeat containing 4



chr2_+_33661382 0.183 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr19_+_7895074 0.183 ENST00000270530.4
EVI5L
ecotropic viral integration site 5-like
chr1_+_101702417 0.180 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr20_-_31124186 0.172 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr17_-_56084578 0.169 ENST00000582730.2
ENST00000584773.1
ENST00000585096.1
ENST00000258962.4
SRSF1



serine/arginine-rich splicing factor 1



chr6_-_33679452 0.169 ENST00000374231.4
ENST00000607484.1
ENST00000374214.3
UQCC2


ubiquinol-cytochrome c reductase complex assembly factor 2


chr7_-_752577 0.168 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
PRKAR1B



protein kinase, cAMP-dependent, regulatory, type I, beta



chr17_-_40306934 0.166 ENST00000550406.1
ENST00000547517.1
ENST00000393860.3
ENST00000346213.4
ENST00000592574.1
RAB5C



CTD-2132N18.3
RAB5C, member RAS oncogene family



Uncharacterized protein
chr5_-_176433350 0.165 ENST00000377227.4
ENST00000377219.2
UIMC1

ubiquitin interaction motif containing 1

chr3_-_52002403 0.159 ENST00000490063.1
ENST00000468324.1
ENST00000497653.1
ENST00000484633.1
PCBP4



poly(rC) binding protein 4



chr6_-_26124138 0.159 ENST00000314332.5
ENST00000396984.1
HIST1H2BC

histone cluster 1, H2bc

chr4_-_186456652 0.157 ENST00000284767.5
ENST00000284770.5
PDLIM3

PDZ and LIM domain 3

chr2_-_103353277 0.157 ENST00000258436.5
MFSD9
major facilitator superfamily domain containing 9
chr2_+_223162866 0.154 ENST00000295226.1
CCDC140
coiled-coil domain containing 140
chr17_+_34640031 0.154 ENST00000339270.6
ENST00000482104.1
CCL4L2

chemokine (C-C motif) ligand 4-like 2

chr8_+_7801144 0.150 ENST00000443676.1
ZNF705B
zinc finger protein 705B
chr1_+_150980889 0.148 ENST00000450884.1
ENST00000271620.3
ENST00000271619.8
ENST00000368937.1
ENST00000431193.1
ENST00000368936.1
PRUNE





prune exopolyphosphatase





chrX_-_69509738 0.148 ENST00000374454.1
ENST00000239666.4
PDZD11

PDZ domain containing 11

chr4_-_186456766 0.147 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr1_+_39456895 0.146 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1


akirin 1


chr17_+_34639793 0.143 ENST00000394465.2
ENST00000394463.2
ENST00000378342.4
CCL4L2


chemokine (C-C motif) ligand 4-like 2


chr3_-_126373929 0.141 ENST00000523403.1
ENST00000524230.2
TXNRD3

thioredoxin reductase 3

chr2_+_108905095 0.139 ENST00000251481.6
ENST00000326853.5
SULT1C2

sulfotransferase family, cytosolic, 1C, member 2

chr17_+_17942594 0.138 ENST00000268719.4
GID4
GID complex subunit 4
chr10_-_115423792 0.134 ENST00000369360.3
ENST00000360478.3
ENST00000359988.3
ENST00000369358.4
NRAP



nebulin-related anchoring protein



chr2_+_58134756 0.133 ENST00000435505.2
ENST00000417641.2
VRK2

vaccinia related kinase 2

chrX_+_16804544 0.131 ENST00000380122.5
ENST00000398155.4
TXLNG

taxilin gamma

chrX_-_48216101 0.130 ENST00000298396.2
ENST00000376893.3
SSX3

synovial sarcoma, X breakpoint 3

chr1_+_113009163 0.124 ENST00000256640.5
WNT2B
wingless-type MMTV integration site family, member 2B
chr8_-_141810634 0.123 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
PTK2


protein tyrosine kinase 2


chr17_+_47296865 0.118 ENST00000573347.1
ABI3
ABI family, member 3
chr22_-_36031181 0.116 ENST00000594060.1
AL049747.1
AL049747.1
chr15_-_83474806 0.112 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2


fibronectin type III and SPRY domain containing 2


chrX_-_106146547 0.108 ENST00000276173.4
ENST00000411805.1
RIPPLY1

ripply transcriptional repressor 1

chr6_+_83073334 0.106 ENST00000369750.3
TPBG
trophoblast glycoprotein
chr16_+_72459838 0.105 ENST00000564508.1
AC004158.3
AC004158.3
chr4_+_158493642 0.104 ENST00000507108.1
ENST00000455598.1
ENST00000509450.1
RP11-364P22.1


RP11-364P22.1


chr17_-_43502987 0.102 ENST00000376922.2
ARHGAP27
Rho GTPase activating protein 27
chr16_+_77233294 0.100 ENST00000378644.4
SYCE1L
synaptonemal complex central element protein 1-like
chr12_-_49351303 0.100 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chr14_-_94984181 0.098 ENST00000341228.2
SERPINA12
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
chr21_-_15918618 0.097 ENST00000400564.1
ENST00000400566.1
SAMSN1

SAM domain, SH3 domain and nuclear localization signals 1

chrX_+_133594168 0.096 ENST00000298556.7
HPRT1
hypoxanthine phosphoribosyltransferase 1
chr2_+_162087577 0.095 ENST00000439442.1
TANK
TRAF family member-associated NFKB activator
chr17_-_46657473 0.094 ENST00000332503.5
HOXB4
homeobox B4
chr2_+_176972000 0.094 ENST00000249504.5
HOXD11
homeobox D11
chr3_+_127770455 0.093 ENST00000464451.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr3_+_57741957 0.091 ENST00000295951.3
SLMAP
sarcolemma associated protein
chr22_-_46644182 0.090 ENST00000404583.1
ENST00000404744.1
CDPF1

cysteine-rich, DPF motif domain containing 1

chr17_-_74533734 0.083 ENST00000589342.1
CYGB
cytoglobin
chr4_-_151936865 0.082 ENST00000535741.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr8_-_99954788 0.081 ENST00000523601.1
STK3
serine/threonine kinase 3
chr17_-_33446820 0.079 ENST00000592577.1
ENST00000590016.1
ENST00000345365.6
ENST00000360276.3
ENST00000357906.3
RAD51D




RAD51 paralog D




chr22_-_32341336 0.079 ENST00000248984.3
C22orf24
chromosome 22 open reading frame 24
chr20_+_1115821 0.078 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr17_-_17942473 0.077 ENST00000585101.1
ENST00000474627.3
ENST00000444058.1
ATPAF2


ATP synthase mitochondrial F1 complex assembly factor 2


chr2_-_219031709 0.077 ENST00000295683.2
CXCR1
chemokine (C-X-C motif) receptor 1
chr2_+_233320827 0.076 ENST00000295463.3
ALPI
alkaline phosphatase, intestinal
chr21_+_27107672 0.076 ENST00000400075.3
GABPA
GA binding protein transcription factor, alpha subunit 60kDa
chr12_-_53074182 0.075 ENST00000252244.3
KRT1
keratin 1
chr10_-_97050777 0.075 ENST00000329399.6
PDLIM1
PDZ and LIM domain 1
chr10_-_79789291 0.074 ENST00000372371.3
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr19_-_1021113 0.072 ENST00000333175.5
ENST00000356663.3
TMEM259

transmembrane protein 259

chr1_-_204165610 0.072 ENST00000367194.4
KISS1
KiSS-1 metastasis-suppressor
chr14_+_101908402 0.069 ENST00000555725.1
RP11-168L7.3
RP11-168L7.3
chr2_+_108905325 0.067 ENST00000438339.1
ENST00000409880.1
ENST00000437390.2
SULT1C2


sulfotransferase family, cytosolic, 1C, member 2


chr15_-_83621435 0.064 ENST00000450735.2
ENST00000426485.1
ENST00000399166.2
ENST00000304231.8
HOMER2



homer homolog 2 (Drosophila)



chr7_-_229557 0.064 ENST00000514988.1
AC145676.2
Uncharacterized protein
chr4_+_123300664 0.063 ENST00000388725.2
ADAD1
adenosine deaminase domain containing 1 (testis-specific)
chr16_+_69221028 0.062 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr4_-_69817481 0.061 ENST00000251566.4
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr1_+_92417716 0.060 ENST00000402388.1
BRDT
bromodomain, testis-specific
chr4_+_128554081 0.053 ENST00000335251.6
ENST00000296461.5
INTU

inturned planar cell polarity protein

chr7_-_81399411 0.053 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr5_+_139554227 0.051 ENST00000261811.4
CYSTM1
cysteine-rich transmembrane module containing 1
chr20_-_43438912 0.050 ENST00000541604.2
ENST00000372851.3
RIMS4

regulating synaptic membrane exocytosis 4

chr22_+_40441456 0.048 ENST00000402203.1
TNRC6B
trinucleotide repeat containing 6B
chr12_+_128399917 0.044 ENST00000544645.1
LINC00507
long intergenic non-protein coding RNA 507
chr8_-_38326119 0.040 ENST00000356207.5
ENST00000326324.6
FGFR1

fibroblast growth factor receptor 1

chr22_-_41215291 0.040 ENST00000542412.1
ENST00000544408.1
SLC25A17

solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17

chr18_-_77276057 0.039 ENST00000597412.1
AC018445.1
Uncharacterized protein
chr16_-_2314222 0.038 ENST00000566397.1
RNPS1
RNA binding protein S1, serine-rich domain
chr7_-_81399355 0.037 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_-_81399438 0.035 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr1_+_89149905 0.034 ENST00000316005.7
ENST00000370521.3
ENST00000370505.3
PKN2


protein kinase N2


chr5_+_85913721 0.033 ENST00000247655.3
ENST00000509578.1
ENST00000515763.1
COX7C


cytochrome c oxidase subunit VIIc


chr14_-_45603657 0.032 ENST00000396062.3
FKBP3
FK506 binding protein 3, 25kDa
chr2_+_171571827 0.031 ENST00000375281.3
SP5
Sp5 transcription factor
chr15_+_78832747 0.027 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
PSMA4






proteasome (prosome, macropain) subunit, alpha type, 4






chr6_+_43149903 0.024 ENST00000252050.4
ENST00000354495.3
ENST00000372647.2
CUL9


cullin 9


chr2_-_200322723 0.023 ENST00000417098.1
SATB2
SATB homeobox 2
chr19_+_17638059 0.023 ENST00000599164.1
ENST00000449408.2
ENST00000600871.1
ENST00000599124.1
FAM129C



family with sequence similarity 129, member C



chr14_-_69619689 0.019 ENST00000389997.6
ENST00000557386.1
ENST00000554681.1
DCAF5


DDB1 and CUL4 associated factor 5


chr5_-_137610300 0.016 ENST00000274721.3
GFRA3
GDNF family receptor alpha 3
chr14_-_107114267 0.013 ENST00000454421.2
IGHV3-64
immunoglobulin heavy variable 3-64
chr9_+_131452239 0.012 ENST00000372688.4
ENST00000372686.5
SET

SET nuclear oncogene

chr2_+_189839046 0.012 ENST00000304636.3
ENST00000317840.5
COL3A1

collagen, type III, alpha 1

chrX_+_100663243 0.012 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr19_+_55235969 0.010 ENST00000402254.2
ENST00000538269.1
ENST00000541392.1
ENST00000396284.2
ENST00000291860.1
KIR3DL1


KIR2DL4
KIR3DL3
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1


killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
chr12_+_19358228 0.008 ENST00000424268.1
ENST00000543806.1
PLEKHA5

pleckstrin homology domain containing, family A member 5

chr5_-_131329918 0.008 ENST00000357096.1
ENST00000431707.1
ENST00000434099.1
ACSL6


acyl-CoA synthetase long-chain family member 6


chr19_+_17638041 0.007 ENST00000601861.1
FAM129C
family with sequence similarity 129, member C
chr1_+_203765437 0.007 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr7_-_81399329 0.005 ENST00000453411.1
ENST00000444829.2
HGF

hepatocyte growth factor (hepapoietin A; scatter factor)

chr20_+_1093891 0.005 ENST00000333082.3
ENST00000381898.4
ENST00000381899.4
PSMF1


proteasome (prosome, macropain) inhibitor subunit 1 (PI31)


chr1_+_89150245 0.002 ENST00000370513.5
PKN2
protein kinase N2
chr1_+_27648648 0.002 ENST00000374076.4
TMEM222
transmembrane protein 222
chr15_-_34502278 0.001 ENST00000559515.1
ENST00000256544.3
ENST00000560108.1
ENST00000559462.1
KATNBL1



katanin p80 subunit B-like 1




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.3 1.3 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.2 0.9 GO:0035627 ceramide transport(GO:0035627)
0.2 1.5 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.7 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.1 1.0 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 0.6 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.6 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 0.6 GO:0035803 egg coat formation(GO:0035803)
0.1 0.3 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.7 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.3 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
0.1 0.5 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.2 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 1.0 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.3 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.3 GO:0030805 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.2 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.2 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.0 1.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.1 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 3.1 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.4 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.5 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 1.3 GO:0007398 ectoderm development(GO:0007398)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.1 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.0 0.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:0051451 myoblast migration(GO:0051451)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 1.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.3 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 1.0 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0 0.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.3 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.2 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.5 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0035976 AP1 complex(GO:0035976)
0.1 0.9 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 1.3 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.3 GO:0043259 laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.1 1.0 GO:0033010 paranodal junction(GO:0033010)
0.1 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.8 GO:0030478 actin cap(GO:0030478)
0.0 2.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 1.8 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 1.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.3 1.4 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 1.0 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.2 0.9 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.2 0.5 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.7 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.1 1.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.8 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.6 GO:0032190 acrosin binding(GO:0032190)
0.0 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 1.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0016015 morphogen activity(GO:0016015)
0.0 1.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 1.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.3 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.8 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.4 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 1.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.3 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.3 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 1.6 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.0 0.3 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 0.4 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.5 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.8 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.9 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.3 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.3 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 1.4 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.8 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.2 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR