Motif ID: TCF21

Z-value: 1.454


Transcription factors associated with TCF21:

Gene SymbolEntrez IDGene Name
TCF21 ENSG00000118526.6 TCF21

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TCF21hg19_v2_chr6_+_134210243_1342102760.038.9e-01Click!


Activity profile for motif TCF21.

activity profile for motif TCF21


Sorted Z-values histogram for motif TCF21

Sorted Z-values for motif TCF21



Network of associatons between targets according to the STRING database.



First level regulatory network of TCF21

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_205391178 6.659 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1



LEM domain containing 1



chr22_+_38071615 5.782 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr17_-_7493390 4.992 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SOX15


SRY (sex determining region Y)-box 15


chrX_+_69509927 4.667 ENST00000374403.3
KIF4A
kinesin family member 4A
chr1_+_171154347 4.523 ENST00000209929.7
ENST00000441535.1
FMO2

flavin containing monooxygenase 2 (non-functional)

chr7_-_41742697 4.111 ENST00000242208.4
INHBA
inhibin, beta A
chr20_-_52790055 3.262 ENST00000395955.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr17_+_6347729 3.247 ENST00000572447.1
FAM64A
family with sequence similarity 64, member A
chr17_+_6347761 3.201 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
FAM64A




family with sequence similarity 64, member A




chr17_-_43025005 3.143 ENST00000587309.1
ENST00000593135.1
ENST00000339151.4
KIF18B


kinesin family member 18B


chr18_+_21529811 3.078 ENST00000588004.1
LAMA3
laminin, alpha 3
chr16_-_46655538 2.963 ENST00000303383.3
SHCBP1
SHC SH2-domain binding protein 1
chr12_-_6960407 2.686 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
CDCA3



cell division cycle associated 3



chr5_-_59995921 2.644 ENST00000453022.2
ENST00000545085.1
ENST00000265036.5
DEPDC1B


DEP domain containing 1B


chr20_+_30327063 2.619 ENST00000300403.6
ENST00000340513.4
TPX2

TPX2, microtubule-associated

chr5_+_68463043 2.610 ENST00000508407.1
ENST00000505500.1
CCNB1

cyclin B1

chr12_-_52845910 2.539 ENST00000252252.3
KRT6B
keratin 6B
chr5_+_68462944 2.528 ENST00000506572.1
CCNB1
cyclin B1
chr11_+_125496619 2.521 ENST00000532669.1
ENST00000278916.3
CHEK1

checkpoint kinase 1

chr11_+_125496400 2.475 ENST00000524737.1
CHEK1
checkpoint kinase 1
chr20_-_54967187 2.470 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
AURKA













aurora kinase A













chr17_+_62223320 2.443 ENST00000580828.1
ENST00000582965.1
SNORA76

small nucleolar RNA, H/ACA box 76

chr11_+_33061543 2.432 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1


t-complex 11, testis-specific-like 1


chr20_-_23030296 2.395 ENST00000377103.2
THBD
thrombomodulin
chr5_+_68462837 2.381 ENST00000256442.5
CCNB1
cyclin B1
chr1_-_204135450 2.238 ENST00000272190.8
ENST00000367195.2
REN

renin

chr15_+_63354769 2.096 ENST00000558910.1
TPM1
tropomyosin 1 (alpha)
chr11_+_125496124 2.093 ENST00000533778.2
ENST00000534070.1
CHEK1

checkpoint kinase 1

chr20_-_46415297 2.086 ENST00000467815.1
ENST00000359930.4
SULF2

sulfatase 2

chr7_-_76255444 2.067 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr9_+_125137565 2.056 ENST00000373698.5
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr11_-_87908600 2.053 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38


RAB38, member RAS oncogene family


chr12_-_52585765 1.872 ENST00000313234.5
ENST00000394815.2
KRT80

keratin 80

chr13_-_20767037 1.855 ENST00000382848.4
GJB2
gap junction protein, beta 2, 26kDa
chr2_-_234763147 1.831 ENST00000411486.2
ENST00000432087.1
ENST00000441687.1
ENST00000414924.1
HJURP



Holliday junction recognition protein



chr17_+_39261584 1.763 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr5_-_16936340 1.739 ENST00000507288.1
ENST00000513610.1
MYO10

myosin X

chr19_+_48216600 1.729 ENST00000263277.3
ENST00000538399.1
EHD2

EH-domain containing 2

chr19_+_11651942 1.694 ENST00000587087.1
CNN1
calponin 1, basic, smooth muscle
chr19_+_16187085 1.694 ENST00000300933.4
TPM4
tropomyosin 4
chr19_-_43702231 1.690 ENST00000597374.1
ENST00000599371.1
PSG4

pregnancy specific beta-1-glycoprotein 4

chr17_+_41476327 1.689 ENST00000320033.4
ARL4D
ADP-ribosylation factor-like 4D
chr11_+_47270475 1.672 ENST00000481889.2
ENST00000436778.1
ENST00000531660.1
ENST00000407404.1
NR1H3



nuclear receptor subfamily 1, group H, member 3



chr1_+_153600869 1.644 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100A1


S100 calcium binding protein A1


chr7_-_128045984 1.635 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr15_+_63340858 1.595 ENST00000560615.1
TPM1
tropomyosin 1 (alpha)
chr19_-_4535233 1.561 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5


perilipin 5


chrX_-_106960285 1.552 ENST00000503515.1
ENST00000372397.2
TSC22D3

TSC22 domain family, member 3

chr15_+_89787180 1.512 ENST00000300027.8
ENST00000310775.7
ENST00000567891.1
ENST00000564920.1
ENST00000565255.1
ENST00000567996.1
ENST00000451393.2
ENST00000563250.1
FANCI







Fanconi anemia, complementation group I







chr5_+_135364584 1.505 ENST00000442011.2
ENST00000305126.8
TGFBI

transforming growth factor, beta-induced, 68kDa

chr14_+_24099318 1.483 ENST00000432832.2
DHRS2
dehydrogenase/reductase (SDR family) member 2
chr14_-_106830057 1.481 ENST00000390616.2
IGHV4-34
immunoglobulin heavy variable 4-34
chr15_+_63340734 1.472 ENST00000560959.1
TPM1
tropomyosin 1 (alpha)
chr22_+_44319619 1.437 ENST00000216180.3
PNPLA3
patatin-like phospholipase domain containing 3
chr4_-_4543700 1.413 ENST00000505286.1
ENST00000306200.2
STX18

syntaxin 18

chr15_+_63340647 1.390 ENST00000404484.4
TPM1
tropomyosin 1 (alpha)
chr15_+_63340775 1.376 ENST00000559281.1
ENST00000317516.7
TPM1

tropomyosin 1 (alpha)

chr11_+_72975524 1.358 ENST00000540342.1
ENST00000542092.1
P2RY6

pyrimidinergic receptor P2Y, G-protein coupled, 6

chr11_+_47270436 1.349 ENST00000395397.3
ENST00000405576.1
NR1H3

nuclear receptor subfamily 1, group H, member 3

chr15_+_93447675 1.334 ENST00000536619.1
CHD2
chromodomain helicase DNA binding protein 2
chr11_+_72975578 1.324 ENST00000393592.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr11_+_72975559 1.310 ENST00000349767.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr15_+_63340553 1.295 ENST00000334895.5
TPM1
tropomyosin 1 (alpha)
chr14_-_50154921 1.286 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
POLE2



polymerase (DNA directed), epsilon 2, accessory subunit



chr19_+_11546093 1.277 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr8_-_41522719 1.270 ENST00000335651.6
ANK1
ankyrin 1, erythrocytic
chr17_+_4736627 1.251 ENST00000355280.6
ENST00000347992.7
MINK1

misshapen-like kinase 1

chr1_-_114429997 1.245 ENST00000471267.1
ENST00000393320.3
BCL2L15

BCL2-like 15

chr16_+_18995249 1.237 ENST00000569532.1
ENST00000304381.5
TMC7

transmembrane channel-like 7

chr7_-_44105158 1.233 ENST00000297283.3
PGAM2
phosphoglycerate mutase 2 (muscle)
chrX_+_17755563 1.227 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
SCML1



sex comb on midleg-like 1 (Drosophila)



chr7_-_99698338 1.227 ENST00000354230.3
ENST00000425308.1
MCM7

minichromosome maintenance complex component 7

chr19_+_16186903 1.211 ENST00000588507.1
TPM4
tropomyosin 4
chr20_-_46415341 1.201 ENST00000484875.1
ENST00000361612.4
SULF2

sulfatase 2

chr19_-_40324767 1.174 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
DYRK1B



dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B



chr6_-_30658745 1.154 ENST00000376420.5
ENST00000376421.5
NRM

nurim (nuclear envelope membrane protein)

chr5_-_11589131 1.131 ENST00000511377.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr2_+_7017796 1.129 ENST00000382040.3
RSAD2
radical S-adenosyl methionine domain containing 2
chr1_-_248903150 1.110 ENST00000590317.1
LYPD8
LY6/PLAUR domain containing 8
chr17_-_3417062 1.104 ENST00000570318.1
ENST00000541913.1
SPATA22

spermatogenesis associated 22

chr19_-_4831701 1.077 ENST00000248244.5
TICAM1
toll-like receptor adaptor molecule 1
chr15_-_75017711 1.076 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
CYP1A1





cytochrome P450, family 1, subfamily A, polypeptide 1





chr11_-_7847519 1.072 ENST00000328375.1
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chr13_-_50510622 1.069 ENST00000378195.2
SPRYD7
SPRY domain containing 7
chr1_+_78354297 1.068 ENST00000334785.7
NEXN
nexilin (F actin binding protein)
chr5_-_95158644 1.061 ENST00000237858.6
GLRX
glutaredoxin (thioltransferase)
chr12_+_57828521 1.054 ENST00000309668.2
INHBC
inhibin, beta C
chr8_-_92053212 1.051 ENST00000285419.3
TMEM55A
transmembrane protein 55A
chr17_+_19314505 1.035 ENST00000461366.1
RNF112
ring finger protein 112
chr12_+_122326662 1.027 ENST00000261817.2
ENST00000538613.1
ENST00000542602.1
PSMD9


proteasome (prosome, macropain) 26S subunit, non-ATPase, 9


chr2_-_224702270 1.024 ENST00000396654.2
ENST00000396653.2
ENST00000423110.1
ENST00000443700.1
AP1S3



adaptor-related protein complex 1, sigma 3 subunit



chr19_+_35485682 1.014 ENST00000599564.1
GRAMD1A
GRAM domain containing 1A
chr9_-_113761720 0.992 ENST00000541779.1
ENST00000374430.2
LPAR1

lysophosphatidic acid receptor 1

chr2_-_17981462 0.969 ENST00000402989.1
ENST00000428868.1
SMC6

structural maintenance of chromosomes 6

chr2_-_225811747 0.960 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr11_-_1643368 0.957 ENST00000399682.1
KRTAP5-4
keratin associated protein 5-4
chr1_-_6550625 0.956 ENST00000377725.1
ENST00000340850.5
PLEKHG5

pleckstrin homology domain containing, family G (with RhoGef domain) member 5

chr22_-_23922410 0.955 ENST00000249053.3
IGLL1
immunoglobulin lambda-like polypeptide 1
chr16_-_31100284 0.952 ENST00000280606.6
PRSS53
protease, serine, 53
chr13_-_50510434 0.940 ENST00000361840.3
SPRYD7
SPRY domain containing 7
chr22_+_23264766 0.940 ENST00000390331.2
IGLC7
immunoglobulin lambda constant 7
chr5_-_179050660 0.937 ENST00000519056.1
ENST00000506721.1
ENST00000503105.1
ENST00000504348.1
ENST00000508103.1
ENST00000510431.1
ENST00000515158.1
ENST00000393432.4
ENST00000442819.2
HNRNPH1








heterogeneous nuclear ribonucleoprotein H1 (H)








chr1_+_111772314 0.927 ENST00000466741.1
ENST00000477185.2
CHI3L2

chitinase 3-like 2

chr22_-_22307199 0.926 ENST00000397495.4
ENST00000263212.5
PPM1F

protein phosphatase, Mg2+/Mn2+ dependent, 1F

chr20_-_1309809 0.926 ENST00000360779.3
SDCBP2
syndecan binding protein (syntenin) 2
chr10_-_29923893 0.922 ENST00000355867.4
SVIL
supervillin
chr1_-_85097431 0.921 ENST00000327308.3
C1orf180
chromosome 1 open reading frame 180
chr9_+_118950325 0.916 ENST00000534838.1
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr9_+_27109133 0.910 ENST00000519097.1
ENST00000380036.4
TEK

TEK tyrosine kinase, endothelial

chr12_-_104443890 0.894 ENST00000547583.1
ENST00000360814.4
ENST00000546851.1
GLT8D2


glycosyltransferase 8 domain containing 2


chr12_+_113659234 0.889 ENST00000551096.1
ENST00000551099.1
ENST00000335509.6
ENST00000552897.1
ENST00000550785.1
ENST00000549279.1
TPCN1





two pore segment channel 1





chr1_+_55013889 0.888 ENST00000343744.2
ENST00000371316.3
ACOT11

acyl-CoA thioesterase 11

chr6_-_11382478 0.883 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
NEDD9



neural precursor cell expressed, developmentally down-regulated 9



chr11_-_102496063 0.854 ENST00000260228.2
MMP20
matrix metallopeptidase 20
chr17_+_7341586 0.846 ENST00000575235.1
FGF11
fibroblast growth factor 11
chr3_-_176915215 0.840 ENST00000457928.2
ENST00000422442.1
TBL1XR1

transducin (beta)-like 1 X-linked receptor 1

chr17_-_7297833 0.837 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3



TMEM256-PLSCR3 readthrough (NMD candidate)



chr1_-_228604328 0.834 ENST00000355586.4
ENST00000366698.2
ENST00000520264.1
ENST00000479800.1
ENST00000295033.3
TRIM17




tripartite motif containing 17




chr16_+_81678957 0.822 ENST00000398040.4
CMIP
c-Maf inducing protein
chr1_-_230513367 0.816 ENST00000321327.2
ENST00000525115.1
PGBD5

piggyBac transposable element derived 5

chr14_-_91282726 0.813 ENST00000328459.6
ENST00000357056.2
TTC7B

tetratricopeptide repeat domain 7B

chr6_-_26250835 0.810 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr6_+_150070857 0.805 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr17_-_72772462 0.795 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9







N-acetyltransferase 9 (GCN5-related, putative)







chrX_+_48432892 0.785 ENST00000376759.3
ENST00000430348.2
RBM3

RNA binding motif (RNP1, RRM) protein 3

chr1_-_149889382 0.774 ENST00000369145.1
ENST00000369146.3
SV2A

synaptic vesicle glycoprotein 2A

chr5_-_179050066 0.772 ENST00000329433.6
ENST00000510411.1
HNRNPH1

heterogeneous nuclear ribonucleoprotein H1 (H)

chr7_-_47988088 0.761 ENST00000289672.2
PKD1L1
polycystic kidney disease 1 like 1
chr11_+_117103441 0.759 ENST00000531287.1
ENST00000531452.1
RNF214

ring finger protein 214

chr11_-_14913190 0.757 ENST00000532378.1
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr6_+_31555045 0.752 ENST00000396101.3
ENST00000490742.1
LST1

leukocyte specific transcript 1

chr2_+_192110199 0.748 ENST00000304164.4
MYO1B
myosin IB
chr11_-_114430570 0.740 ENST00000251921.2
NXPE1
neurexophilin and PC-esterase domain family, member 1
chr6_-_143771799 0.732 ENST00000237283.8
ADAT2
adenosine deaminase, tRNA-specific 2
chr7_+_1748798 0.723 ENST00000561626.1
ELFN1
extracellular leucine-rich repeat and fibronectin type III domain containing 1
chr11_-_5323226 0.719 ENST00000380224.1
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr4_+_37892682 0.716 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1


TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1


chr22_-_23922448 0.716 ENST00000438703.1
ENST00000330377.2
IGLL1

immunoglobulin lambda-like polypeptide 1

chr4_-_89152474 0.715 ENST00000515655.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr7_+_20687017 0.713 ENST00000258738.6
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr16_+_2022036 0.708 ENST00000568546.1
TBL3
transducin (beta)-like 3
chr2_-_152590946 0.706 ENST00000172853.10
NEB
nebulin
chr2_+_61244697 0.697 ENST00000401576.1
ENST00000295030.5
ENST00000414712.2
PEX13


peroxisomal biogenesis factor 13


chr15_+_83776137 0.687 ENST00000322019.9
TM6SF1
transmembrane 6 superfamily member 1
chr15_-_65407524 0.687 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr18_+_3247779 0.685 ENST00000578611.1
ENST00000583449.1
MYL12A

myosin, light chain 12A, regulatory, non-sarcomeric

chr19_-_1650666 0.683 ENST00000588136.1
TCF3
transcription factor 3
chr1_-_9129735 0.669 ENST00000377424.4
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr4_-_153303658 0.667 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr12_+_69201923 0.655 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2





MDM2 oncogene, E3 ubiquitin protein ligase





chr21_-_33651324 0.639 ENST00000290130.3
MIS18A
MIS18 kinetochore protein A
chr10_-_79398250 0.638 ENST00000286627.5
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr8_+_91803695 0.637 ENST00000417640.2
NECAB1
N-terminal EF-hand calcium binding protein 1
chr2_-_106054952 0.625 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2


four and a half LIM domains 2


chr8_-_55014415 0.622 ENST00000522007.1
ENST00000521898.1
ENST00000518546.1
ENST00000316963.3
LYPLA1



lysophospholipase I



chr3_-_81792780 0.617 ENST00000489715.1
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr6_+_31554962 0.617 ENST00000376092.3
ENST00000376086.3
ENST00000303757.8
ENST00000376093.2
ENST00000376102.3
LST1




leukocyte specific transcript 1




chr11_+_6947720 0.615 ENST00000414517.2
ZNF215
zinc finger protein 215
chrX_-_150067069 0.605 ENST00000466436.1
CD99L2
CD99 molecule-like 2
chr3_+_101498269 0.604 ENST00000491511.2
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr6_-_27835357 0.600 ENST00000331442.3
HIST1H1B
histone cluster 1, H1b
chr16_+_56703737 0.586 ENST00000569155.1
MT1H
metallothionein 1H
chr6_-_25830785 0.582 ENST00000468082.1
SLC17A1
solute carrier family 17 (organic anion transporter), member 1
chr19_-_46288917 0.581 ENST00000537879.1
ENST00000596586.1
ENST00000595946.1
DMWD
AC011530.4

dystrophia myotonica, WD repeat containing
Uncharacterized protein

chr4_+_123844225 0.577 ENST00000274008.4
SPATA5
spermatogenesis associated 5
chr7_-_132766818 0.571 ENST00000262570.5
CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr2_+_33701286 0.570 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_-_243326612 0.567 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170


centrosomal protein 170kDa


chr5_+_121647924 0.566 ENST00000414317.2
SNCAIP
synuclein, alpha interacting protein
chr2_-_175629135 0.563 ENST00000409542.1
ENST00000409219.1
CHRNA1

cholinergic receptor, nicotinic, alpha 1 (muscle)

chr4_+_164415594 0.558 ENST00000509657.1
ENST00000358572.5
TMA16

translation machinery associated 16 homolog (S. cerevisiae)

chr6_+_31554779 0.557 ENST00000376090.2
LST1
leukocyte specific transcript 1
chr18_+_55888767 0.552 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase


chr15_-_67546963 0.549 ENST00000561452.1
ENST00000261880.5
AAGAB

alpha- and gamma-adaptin binding protein

chr18_+_158513 0.547 ENST00000400266.3
ENST00000580410.1
ENST00000383589.2
ENST00000261601.7
USP14



ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)



chr10_-_46641003 0.546 ENST00000395721.2
ENST00000374218.2
ENST00000395725.3
ENST00000374346.3
ENST00000417004.1
PTPN20A




protein tyrosine phosphatase, non-receptor type 20A




chr8_+_38585704 0.543 ENST00000519416.1
ENST00000520615.1
TACC1

transforming, acidic coiled-coil containing protein 1

chr22_+_40742512 0.540 ENST00000454266.2
ENST00000342312.6
ADSL

adenylosuccinate lyase

chr12_+_9142131 0.540 ENST00000356986.3
ENST00000266551.4
KLRG1

killer cell lectin-like receptor subfamily G, member 1

chr1_-_150849174 0.535 ENST00000515192.1
ARNT
aryl hydrocarbon receptor nuclear translocator
chr17_-_63052929 0.532 ENST00000439174.2
GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr2_-_228028829 0.530 ENST00000396625.3
ENST00000329662.7
COL4A4

collagen, type IV, alpha 4

chr20_+_54823788 0.527 ENST00000243911.2
MC3R
melanocortin 3 receptor
chr2_+_90273679 0.525 ENST00000423080.2
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr12_-_11002063 0.522 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
PRR4


proline rich 4 (lacrimal)


chr11_-_82997371 0.519 ENST00000525503.1
CCDC90B
coiled-coil domain containing 90B
chr4_-_186347099 0.519 ENST00000505357.1
ENST00000264689.6
UFSP2

UFM1-specific peptidase 2

chr1_+_25870070 0.518 ENST00000374338.4
LDLRAP1
low density lipoprotein receptor adaptor protein 1
chr11_-_14913765 0.517 ENST00000334636.5
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr11_+_74862100 0.509 ENST00000532236.1
ENST00000531756.1
SLCO2B1

solute carrier organic anion transporter family, member 2B1

chr8_-_68658578 0.509 ENST00000518549.1
ENST00000297770.4
ENST00000297769.4
CPA6


carboxypeptidase A6


chr7_-_132766800 0.509 ENST00000542753.1
ENST00000448878.1
CHCHD3

coiled-coil-helix-coiled-coil-helix domain containing 3

chr2_+_56411131 0.504 ENST00000407595.2
CCDC85A
coiled-coil domain containing 85A
chr4_+_37962018 0.503 ENST00000504686.1
PTTG2
pituitary tumor-transforming 2
chr11_+_74862140 0.501 ENST00000525650.1
ENST00000454962.2
SLCO2B1

solute carrier organic anion transporter family, member 2B1

chr6_+_155470243 0.498 ENST00000456877.2
ENST00000528391.2
TIAM2

T-cell lymphoma invasion and metastasis 2

chr14_-_50559361 0.495 ENST00000305273.1
C14orf183
chromosome 14 open reading frame 183
chr12_+_112563335 0.495 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAFD1



TRAF-type zinc finger domain containing 1



chr20_+_816695 0.490 ENST00000246100.3
FAM110A
family with sequence similarity 110, member A
chr19_-_4867665 0.487 ENST00000592528.1
ENST00000589494.1
ENST00000585479.1
ENST00000221957.4
PLIN3



perilipin 3




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
1.7 5.0 GO:0048627 myoblast development(GO:0048627)
1.4 4.1 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
1.2 6.2 GO:0002317 plasma cell differentiation(GO:0002317)
1.2 7.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
1.2 9.2 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
1.1 3.3 GO:0042369 vitamin D catabolic process(GO:0042369)
1.0 3.0 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.8 2.5 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.8 3.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.7 4.1 GO:0070995 NADPH oxidation(GO:0070995)
0.5 1.6 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.4 2.2 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.4 1.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) cellular alkene metabolic process(GO:0043449)
0.4 1.4 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.3 2.1 GO:0035803 egg coat formation(GO:0035803)
0.3 1.3 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.3 1.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.3 4.7 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.3 2.1 GO:1903232 melanosome assembly(GO:1903232)
0.3 0.9 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.3 3.7 GO:0030321 transepithelial chloride transport(GO:0030321)
0.3 1.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.3 1.6 GO:0006177 GMP biosynthetic process(GO:0006177)
0.3 0.8 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.2 1.0 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 1.7 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.2 0.7 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.2 1.1 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.2 0.7 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.2 2.8 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.2 0.8 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.2 0.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.2 1.6 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 0.8 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 0.7 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.2 0.5 GO:0019085 early viral transcription(GO:0019085)
0.2 0.5 GO:0006624 vacuolar protein processing(GO:0006624)
0.2 0.8 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.2 0.6 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.1 0.7 GO:0048749 compound eye development(GO:0048749)
0.1 0.7 GO:0007525 somatic muscle development(GO:0007525)
0.1 1.6 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.1 1.1 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1 0.7 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.5 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.1 0.6 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 1.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 1.4 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.1 0.5 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.8 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 2.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.3 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 1.5 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 0.5 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 3.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.8 GO:0060613 fat pad development(GO:0060613)
0.1 0.9 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.9 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 0.9 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 0.6 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.3 GO:0040010 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.1 0.8 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 0.7 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.2 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 1.0 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 0.2 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.1 0.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.4 GO:0072313 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.1 0.6 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 1.6 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 1.0 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.8 GO:0030091 protein repair(GO:0030091)
0.1 0.2 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.4 GO:0048539 bone marrow development(GO:0048539)
0.1 1.3 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.9 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.5 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.1 0.3 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 0.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 1.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 2.5 GO:0007398 ectoderm development(GO:0007398)
0.1 0.5 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.1 0.3 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 0.3 GO:0006939 smooth muscle contraction(GO:0006939)
0.1 3.9 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 2.3 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.7 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 1.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.2 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 2.6 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.2 GO:1904647 response to rotenone(GO:1904647)
0.1 0.2 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 1.1 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.1 0.8 GO:0002097 tRNA wobble base modification(GO:0002097)
0.1 0.2 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 0.5 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 1.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.2 GO:1990637 response to prolactin(GO:1990637)
0.0 0.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.5 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 1.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.9 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.2 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 1.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 1.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.3 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.4 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 3.0 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.0 0.4 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 1.1 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 1.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:1901656 glycoside transport(GO:1901656)
0.0 0.4 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.6 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 1.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.7 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 1.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 3.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.2 GO:1905245 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 1.0 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 1.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.3 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.0 0.5 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.6 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.1 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 3.9 GO:0031424 keratinization(GO:0031424)
0.0 1.8 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 0.7 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 1.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 1.5 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.4 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 1.9 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 1.1 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.8 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 2.7 GO:0051017 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.0 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.4 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 1.1 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.3 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.5 GO:0045687 positive regulation of glial cell differentiation(GO:0045687)
0.0 0.5 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
0.0 1.7 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0019233 sensory perception of pain(GO:0019233)
0.0 0.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.3 GO:0051354 negative regulation of oxidoreductase activity(GO:0051354)
0.0 0.2 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.2 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.3 GO:0030866 cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0 0.4 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.3 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 2.9 GO:0007015 actin filament organization(GO:0007015)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.5 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
1.4 4.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.6 12.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.6 2.5 GO:0001674 female germ cell nucleus(GO:0001674)
0.4 2.1 GO:0031905 early endosome lumen(GO:0031905)
0.4 3.1 GO:0005610 laminin-5 complex(GO:0005610)
0.3 3.1 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.2 1.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 2.6 GO:0043203 axon hillock(GO:0043203)
0.2 1.0 GO:0035061 interchromatin granule(GO:0035061)
0.2 0.9 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.9 GO:0097449 astrocyte projection(GO:0097449)
0.1 1.1 GO:0061617 MICOS complex(GO:0061617)
0.1 0.7 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 6.4 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.7 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 1.7 GO:0032433 filopodium tip(GO:0032433)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 2.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.2 GO:0042555 MCM complex(GO:0042555)
0.1 6.4 GO:0045095 keratin filament(GO:0045095)
0.1 0.5 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.9 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 1.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.5 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.5 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.3 GO:0000798 nuclear cohesin complex(GO:0000798)
0.1 0.5 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 7.1 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 2.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.5 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 1.1 GO:0097342 ripoptosome(GO:0097342)
0.1 0.7 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.7 GO:0000813 ESCRT I complex(GO:0000813)
0.0 4.9 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 2.3 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.8 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 0.5 GO:0070652 HAUS complex(GO:0070652)
0.0 0.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 9.1 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 2.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0005602 complement component C1 complex(GO:0005602)
0.0 3.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.7 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0005902 microvillus(GO:0005902)
0.0 0.8 GO:0045202 synapse(GO:0045202)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 1.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.5 GO:0016459 myosin complex(GO:0016459)
0.0 1.0 GO:0031201 SNARE complex(GO:0031201)
0.0 1.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 6.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 3.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.8 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.5 GO:0097546 mediator complex(GO:0016592) ciliary base(GO:0097546)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.2 GO:0005901 caveola(GO:0005901)
0.0 0.6 GO:0005771 multivesicular body(GO:0005771)
0.0 0.2 GO:0097440 apical dendrite(GO:0097440)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.5 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 2.6 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.8 GO:0030395 lactose binding(GO:0030395)
1.4 4.1 GO:0070699 type II activin receptor binding(GO:0070699)
1.2 7.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
1.1 7.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.9 4.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.7 4.0 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.6 1.3 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.6 3.0 GO:0032810 sterol response element binding(GO:0032810)
0.5 3.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.5 2.6 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.5 2.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.5 2.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.4 3.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 1.6 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.3 1.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.3 1.5 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.3 2.5 GO:0035174 histone serine kinase activity(GO:0035174)
0.2 2.4 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.2 0.9 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.2 0.7 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.2 0.7 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.2 2.1 GO:0032190 acrosin binding(GO:0032190)
0.2 1.7 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.2 0.5 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.2 1.6 GO:0043426 MRF binding(GO:0043426)
0.2 1.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.2 0.3 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 1.0 GO:0035473 lipase binding(GO:0035473)
0.1 0.7 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.8 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.5 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 1.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 14.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 4.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.5 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 0.9 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.3 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.3 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 1.9 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.9 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.5 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.3 GO:0031768 ghrelin receptor binding(GO:0031768)
0.1 0.7 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 2.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.2 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.1 1.6 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 1.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 1.1 GO:0005549 odorant binding(GO:0005549)
0.1 0.9 GO:0004568 chitinase activity(GO:0004568)
0.1 0.5 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 1.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.8 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.6 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 2.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 1.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 3.2 GO:0042169 SH2 domain binding(GO:0042169)
0.1 3.4 GO:0019894 kinesin binding(GO:0019894)
0.1 1.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 2.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.5 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.7 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 1.0 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.9 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 1.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 1.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.6 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 1.4 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 1.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 1.1 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.4 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 1.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 2.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.7 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 3.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.7 GO:0042393 histone binding(GO:0042393)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.1 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 12.6 PID_PLK1_PATHWAY PLK1 signaling events
0.1 3.1 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 6.9 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 3.8 PID_ALK1_PATHWAY ALK1 signaling events
0.1 2.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.2 PID_ATR_PATHWAY ATR signaling pathway
0.0 2.4 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.7 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 2.0 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 0.9 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.7 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 1.5 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 1.2 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.6 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.2 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.3 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 1.0 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.5 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.6 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.0 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.8 PID_SHP2_PATHWAY SHP2 signaling
0.0 0.7 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.6 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.3 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.2 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 3.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 14.6 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.4 5.2 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.2 4.0 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.2 12.4 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.4 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.1 5.0 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.1 4.7 REACTOME_KINESINS Genes involved in Kinesins
0.1 2.2 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 7.2 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.9 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 1.1 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.3 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.3 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 1.2 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 0.7 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.9 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.1 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 2.3 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 1.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.9 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.7 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 2.3 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 3.6 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 1.1 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 2.5 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.9 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.8 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 3.1 REACTOME_CELL_JUNCTION_ORGANIZATION Genes involved in Cell junction organization
0.0 1.2 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 3.0 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 1.0 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 1.9 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.7 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.5 REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.3 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.7 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 3.6 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.7 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.5 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.1 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.4 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.6 REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 1.4 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis