Motif ID: TFAP4_MSC

Z-value: 0.712

Transcription factors associated with TFAP4_MSC:

Gene SymbolEntrez IDGene Name
MSC ENSG00000178860.8 MSC
TFAP4 ENSG00000090447.7 TFAP4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MSChg19_v2_chr8_-_72756667_72756736-0.377.9e-02Click!
TFAP4hg19_v2_chr16_-_4323015_43230760.058.0e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP4_MSC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_24911195 4.509 ENST00000259698.4
FAM65B
family with sequence similarity 65, member B
chr16_-_21289627 3.732 ENST00000396023.2
ENST00000415987.2
CRYM

crystallin, mu

chr3_+_3841108 3.636 ENST00000319331.3
LRRN1
leucine rich repeat neuronal 1
chr16_-_67427389 2.910 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
TPPP3


tubulin polymerization-promoting protein family member 3


chr6_-_39197226 2.237 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chr8_-_72274095 2.231 ENST00000303824.7
EYA1
eyes absent homolog 1 (Drosophila)
chr20_-_39317868 1.948 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr15_-_40401062 1.928 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
BMF



Bcl2 modifying factor



chr2_+_85981008 1.842 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr11_+_45918092 1.729 ENST00000395629.2
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr8_-_110660999 1.712 ENST00000424158.2
ENST00000533895.1
ENST00000446070.2
ENST00000528331.1
ENST00000526302.1
ENST00000433638.1
ENST00000408908.2
ENST00000524720.1
SYBU







syntabulin (syntaxin-interacting)







chr6_+_17281573 1.557 ENST00000379052.5
RBM24
RNA binding motif protein 24
chr4_+_75858318 1.495 ENST00000307428.7
PARM1
prostate androgen-regulated mucin-like protein 1
chr22_-_36013368 1.349 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB



myoglobin



chr9_-_112970436 1.316 ENST00000400613.4
C9orf152
chromosome 9 open reading frame 152
chr8_+_81398444 1.311 ENST00000455036.3
ENST00000426744.2
ZBTB10

zinc finger and BTB domain containing 10

chr12_+_49297899 1.257 ENST00000552942.1
ENST00000320516.4
CCDC65

coiled-coil domain containing 65

chr4_+_75858290 1.257 ENST00000513238.1
PARM1
prostate androgen-regulated mucin-like protein 1
chr8_-_72274467 1.199 ENST00000340726.3
EYA1
eyes absent homolog 1 (Drosophila)
chr1_-_216896780 1.186 ENST00000459955.1
ENST00000366937.1
ENST00000408911.3
ENST00000391890.3
ESRRG



estrogen-related receptor gamma



chr5_+_50678921 1.162 ENST00000230658.7
ISL1
ISL LIM homeobox 1
chr22_+_31003133 1.139 ENST00000405742.3
TCN2
transcobalamin II
chr1_+_212738676 1.126 ENST00000366981.4
ENST00000366987.2
ATF3

activating transcription factor 3

chr22_+_31002779 1.112 ENST00000215838.3
TCN2
transcobalamin II
chr8_+_81397876 1.080 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr17_+_4981535 1.077 ENST00000318833.3
ZFP3
ZFP3 zinc finger protein
chr12_+_104458235 1.073 ENST00000229330.4
HCFC2
host cell factor C2
chr10_+_94594351 1.043 ENST00000371552.4
EXOC6
exocyst complex component 6
chr10_-_102089729 1.020 ENST00000465680.2
PKD2L1
polycystic kidney disease 2-like 1
chr1_-_150669500 0.991 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr2_+_233562015 0.976 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GIGYF2














GRB10 interacting GYF protein 2














chr21_-_34185944 0.967 ENST00000479548.1
C21orf62
chromosome 21 open reading frame 62
chr4_+_74702214 0.948 ENST00000226317.5
ENST00000515050.1
CXCL6

chemokine (C-X-C motif) ligand 6

chr15_+_67547163 0.947 ENST00000335894.4
IQCH
IQ motif containing H
chr1_-_183622442 0.943 ENST00000308641.4
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr11_-_85430204 0.934 ENST00000389958.3
ENST00000527794.1
SYTL2

synaptotagmin-like 2

chr11_-_85430163 0.898 ENST00000529581.1
ENST00000533577.1
SYTL2

synaptotagmin-like 2

chr3_-_183273477 0.852 ENST00000341319.3
KLHL6
kelch-like family member 6
chr16_+_83932684 0.845 ENST00000262430.4
MLYCD
malonyl-CoA decarboxylase
chr17_+_68071389 0.832 ENST00000283936.1
ENST00000392671.1
KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr17_+_68071458 0.827 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr1_+_167063282 0.812 ENST00000361200.2
DUSP27
dual specificity phosphatase 27 (putative)
chr3_+_49057876 0.810 ENST00000326912.4
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr1_+_14075865 0.779 ENST00000413440.1
PRDM2
PR domain containing 2, with ZNF domain
chr22_+_35776828 0.769 ENST00000216117.8
HMOX1
heme oxygenase (decycling) 1
chr7_-_120497178 0.769 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12


tetraspanin 12


chr11_+_73675873 0.760 ENST00000537753.1
ENST00000542350.1
DNAJB13

DnaJ (Hsp40) homolog, subfamily B, member 13

chr7_-_30029574 0.738 ENST00000426154.1
ENST00000421434.1
ENST00000434476.2
SCRN1


secernin 1


chr3_+_49058444 0.738 ENST00000326925.6
ENST00000395458.2
NDUFAF3

NADH dehydrogenase (ubiquinone) complex I, assembly factor 3

chr22_+_31003190 0.710 ENST00000407817.3
TCN2
transcobalamin II
chr12_+_56473628 0.710 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3


v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3


chr4_+_86699834 0.706 ENST00000395183.2
ARHGAP24
Rho GTPase activating protein 24
chr2_-_158345462 0.692 ENST00000439355.1
ENST00000540637.1
CYTIP

cytohesin 1 interacting protein

chr7_-_30029367 0.673 ENST00000242059.5
SCRN1
secernin 1
chr16_-_31076332 0.672 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
ZNF668


zinc finger protein 668


chr1_-_39339777 0.662 ENST00000397572.2
MYCBP
MYC binding protein
chr12_+_49297887 0.658 ENST00000266984.5
CCDC65
coiled-coil domain containing 65
chr2_-_27603582 0.645 ENST00000323703.6
ENST00000436006.1
ZNF513

zinc finger protein 513

chr11_+_7597639 0.643 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_+_110082487 0.640 ENST00000527748.1
GPR61
G protein-coupled receptor 61
chr2_-_73460334 0.630 ENST00000258083.2
PRADC1
protease-associated domain containing 1
chr2_+_97203082 0.628 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr7_+_128784712 0.616 ENST00000289407.4
TSPAN33
tetraspanin 33
chr3_-_120365866 0.615 ENST00000475447.2
HGD
homogentisate 1,2-dioxygenase
chr15_+_43809797 0.584 ENST00000399453.1
ENST00000300231.5
MAP1A

microtubule-associated protein 1A

chr14_-_53019211 0.582 ENST00000557374.1
ENST00000281741.4
TXNDC16

thioredoxin domain containing 16

chr19_+_18208603 0.581 ENST00000262811.6
MAST3
microtubule associated serine/threonine kinase 3
chr6_-_76203345 0.565 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr1_+_15272271 0.557 ENST00000400797.3
KAZN
kazrin, periplakin interacting protein
chr3_-_65583561 0.556 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr5_+_102201687 0.554 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr12_+_72233487 0.552 ENST00000482439.2
ENST00000550746.1
ENST00000491063.1
ENST00000319106.8
ENST00000485960.2
ENST00000393309.3
TBC1D15





TBC1 domain family, member 15





chr6_-_76203454 0.551 ENST00000237172.7
FILIP1
filamin A interacting protein 1
chr7_-_99869799 0.548 ENST00000436886.2
GATS
GATS, stromal antigen 3 opposite strand
chr2_+_230787201 0.547 ENST00000283946.3
FBXO36
F-box protein 36
chr1_+_14075903 0.535 ENST00000343137.4
ENST00000503842.1
ENST00000407521.3
ENST00000505823.1
PRDM2



PR domain containing 2, with ZNF domain



chr10_+_95848824 0.535 ENST00000371385.3
ENST00000371375.1
PLCE1

phospholipase C, epsilon 1

chr20_+_44098346 0.531 ENST00000372676.3
WFDC2
WAP four-disulfide core domain 2
chr1_-_24741525 0.531 ENST00000374409.1
STPG1
sperm-tail PG-rich repeat containing 1
chr13_-_41635512 0.530 ENST00000405737.2
ELF1
E74-like factor 1 (ets domain transcription factor)
chr12_-_54121261 0.525 ENST00000549784.1
ENST00000262059.4
CALCOCO1

calcium binding and coiled-coil domain 1

chr5_+_102201509 0.525 ENST00000348126.2
ENST00000379787.4
PAM

peptidylglycine alpha-amidating monooxygenase

chr7_+_116660246 0.518 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7





suppression of tumorigenicity 7





chr11_-_62474803 0.510 ENST00000533982.1
ENST00000360796.5
BSCL2

Berardinelli-Seip congenital lipodystrophy 2 (seipin)

chr6_+_46761118 0.508 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr2_+_95537170 0.505 ENST00000295201.4
TEKT4
tektin 4
chr3_-_52486841 0.502 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr12_+_122150646 0.500 ENST00000449592.2
TMEM120B
transmembrane protein 120B
chr6_+_90272027 0.498 ENST00000522441.1
ANKRD6
ankyrin repeat domain 6
chr12_-_54121212 0.497 ENST00000548263.1
ENST00000430117.2
ENST00000550804.1
ENST00000549173.1
ENST00000551900.1
ENST00000546619.1
ENST00000548177.1
ENST00000549349.1
CALCOCO1







calcium binding and coiled-coil domain 1







chr19_+_10527449 0.494 ENST00000592685.1
ENST00000380702.2
PDE4A

phosphodiesterase 4A, cAMP-specific

chrX_-_10851762 0.494 ENST00000380785.1
ENST00000380787.1
MID1

midline 1 (Opitz/BBB syndrome)

chr16_-_31076273 0.485 ENST00000426488.2
ZNF668
zinc finger protein 668
chr5_+_102201722 0.483 ENST00000274392.9
ENST00000455264.2
PAM

peptidylglycine alpha-amidating monooxygenase

chr17_+_58755184 0.480 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3


breast carcinoma amplified sequence 3


chr6_+_44184653 0.477 ENST00000573382.2
ENST00000576476.1
RP1-302G2.5

RP1-302G2.5

chr3_-_193272741 0.477 ENST00000392443.3
ATP13A4
ATPase type 13A4
chr12_+_109826524 0.470 ENST00000431443.2
MYO1H
myosin IH
chr12_+_86268065 0.469 ENST00000551529.1
ENST00000256010.6
NTS

neurotensin

chr20_+_33292068 0.461 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2


tumor protein p53 inducible nuclear protein 2


chr14_-_23288930 0.458 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
SLC7A7



solute carrier family 7 (amino acid transporter light chain, y+L system), member 7



chr3_-_193272874 0.453 ENST00000342695.4
ATP13A4
ATPase type 13A4
chr5_+_102201430 0.451 ENST00000438793.3
ENST00000346918.2
PAM

peptidylglycine alpha-amidating monooxygenase

chr11_+_71498552 0.448 ENST00000346333.6
ENST00000359244.4
ENST00000426628.2
FAM86C1


family with sequence similarity 86, member C1


chr6_-_31697255 0.439 ENST00000436437.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr3_-_64211112 0.438 ENST00000295902.6
PRICKLE2
prickle homolog 2 (Drosophila)
chr1_-_86043921 0.429 ENST00000535924.2
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr15_-_75748115 0.423 ENST00000360439.4
SIN3A
SIN3 transcription regulator family member A
chr17_+_7462031 0.414 ENST00000380535.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr17_+_7462103 0.413 ENST00000396545.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr2_-_148779106 0.409 ENST00000416719.1
ENST00000264169.2
ORC4

origin recognition complex, subunit 4

chr1_+_174844645 0.403 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr14_+_45431379 0.403 ENST00000361577.3
ENST00000361462.2
ENST00000382233.2
FAM179B


family with sequence similarity 179, member B


chr22_+_39052632 0.399 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1



chibby homolog 1 (Drosophila)



chr15_-_52944231 0.398 ENST00000546305.2
FAM214A
family with sequence similarity 214, member A
chr11_+_1944054 0.397 ENST00000397301.1
ENST00000397304.2
ENST00000446240.1
TNNT3


troponin T type 3 (skeletal, fast)


chr20_+_53092123 0.392 ENST00000262593.5
DOK5
docking protein 5
chr8_+_98788003 0.389 ENST00000521545.2
LAPTM4B
lysosomal protein transmembrane 4 beta
chr20_-_40247133 0.388 ENST00000373233.3
ENST00000309279.7
CHD6

chromodomain helicase DNA binding protein 6

chr5_+_49962772 0.386 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8




poly (ADP-ribose) polymerase family, member 8




chr8_+_98788057 0.385 ENST00000517924.1
LAPTM4B
lysosomal protein transmembrane 4 beta
chr1_-_175712665 0.384 ENST00000263525.2
TNR
tenascin R
chr8_-_71581377 0.383 ENST00000276590.4
ENST00000522447.1
LACTB2

lactamase, beta 2

chr4_-_103682145 0.377 ENST00000226578.4
MANBA
mannosidase, beta A, lysosomal
chr1_+_172422026 0.375 ENST00000367725.4
C1orf105
chromosome 1 open reading frame 105
chrX_-_108868390 0.374 ENST00000372101.2
KCNE1L
KCNE1-like
chr1_+_223101757 0.372 ENST00000284476.6
DISP1
dispatched homolog 1 (Drosophila)
chr8_-_95961578 0.368 ENST00000448464.2
ENST00000342697.4
TP53INP1

tumor protein p53 inducible nuclear protein 1

chr14_+_24584508 0.367 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
DCAF11




DDB1 and CUL4 associated factor 11




chr3_-_52868931 0.366 ENST00000486659.1
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr7_-_92855762 0.365 ENST00000453812.2
ENST00000394468.2
HEPACAM2

HEPACAM family member 2

chr20_+_43160409 0.361 ENST00000372894.3
ENST00000372892.3
ENST00000372891.3
PKIG


protein kinase (cAMP-dependent, catalytic) inhibitor gamma


chr18_-_19180681 0.361 ENST00000269214.5
ESCO1
establishment of sister chromatid cohesion N-acetyltransferase 1
chr20_+_53092232 0.358 ENST00000395939.1
DOK5
docking protein 5
chr20_+_62697564 0.357 ENST00000458442.1
TCEA2
transcription elongation factor A (SII), 2
chr6_-_31651817 0.355 ENST00000375863.3
ENST00000375860.2
LY6G5C

lymphocyte antigen 6 complex, locus G5C

chr12_-_50297638 0.355 ENST00000320634.3
FAIM2
Fas apoptotic inhibitory molecule 2
chr11_+_6411670 0.353 ENST00000530395.1
ENST00000527275.1
SMPD1

sphingomyelin phosphodiesterase 1, acid lysosomal

chr6_-_39399087 0.349 ENST00000229913.5
ENST00000541946.1
ENST00000394362.1
KIF6


kinesin family member 6


chr2_+_231280954 0.347 ENST00000409824.1
ENST00000409341.1
ENST00000409112.1
ENST00000340126.4
ENST00000341950.4
SP100




SP100 nuclear antigen




chr17_+_1627834 0.346 ENST00000419248.1
ENST00000418841.1
WDR81

WD repeat domain 81

chr15_+_67547113 0.345 ENST00000512104.1
ENST00000358767.3
ENST00000546225.1
IQCH


IQ motif containing H


chr9_-_123239632 0.340 ENST00000416449.1
CDK5RAP2
CDK5 regulatory subunit associated protein 2
chr9_-_13165457 0.340 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ


multiple PDZ domain protein


chr5_+_43603229 0.337 ENST00000344920.4
ENST00000512996.2
NNT

nicotinamide nucleotide transhydrogenase

chr16_-_5147743 0.332 ENST00000587133.1
ENST00000458008.4
ENST00000427587.4
FAM86A


family with sequence similarity 86, member A


chr2_+_68384976 0.331 ENST00000263657.2
PNO1
partner of NOB1 homolog (S. cerevisiae)
chr20_+_44098385 0.328 ENST00000217425.5
ENST00000339946.3
WFDC2

WAP four-disulfide core domain 2

chr5_+_145583156 0.324 ENST00000265271.5
RBM27
RNA binding motif protein 27
chr8_-_74791051 0.322 ENST00000453587.2
ENST00000602969.1
ENST00000602593.1
ENST00000419880.3
ENST00000517608.1
UBE2W




ubiquitin-conjugating enzyme E2W (putative)




chr11_+_71938925 0.318 ENST00000538751.1
INPPL1
inositol polyphosphate phosphatase-like 1
chr17_-_47755436 0.318 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
SPOP






speckle-type POZ protein






chr19_+_7587491 0.316 ENST00000264079.6
MCOLN1
mucolipin 1
chr17_+_26800648 0.315 ENST00000545060.1
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chrY_+_14774265 0.315 ENST00000457658.1
ENST00000440408.1
ENST00000543097.1
TTTY15


testis-specific transcript, Y-linked 15 (non-protein coding)


chr17_+_26800756 0.313 ENST00000537681.1
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr3_-_52869205 0.310 ENST00000446157.2
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr12_-_50298000 0.306 ENST00000550635.2
FAIM2
Fas apoptotic inhibitory molecule 2
chr11_-_85430088 0.303 ENST00000533057.1
ENST00000533892.1
SYTL2

synaptotagmin-like 2

chr2_+_97202480 0.303 ENST00000357485.3
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr11_+_6411636 0.302 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1


sphingomyelin phosphodiesterase 1, acid lysosomal


chr17_-_7145106 0.301 ENST00000577035.1
GABARAP
GABA(A) receptor-associated protein
chr1_+_159750720 0.301 ENST00000368109.1
ENST00000368108.3
DUSP23

dual specificity phosphatase 23

chr15_-_83680325 0.298 ENST00000508990.2
ENST00000510873.2
ENST00000538348.2
ENST00000451195.3
ENST00000513601.2
ENST00000304177.5
ENST00000565712.1
C15orf40






chromosome 15 open reading frame 40






chr1_+_159750776 0.298 ENST00000368107.1
DUSP23
dual specificity phosphatase 23
chr8_-_38008783 0.297 ENST00000276449.4
STAR
steroidogenic acute regulatory protein
chr4_+_159727272 0.294 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr3_-_49058479 0.293 ENST00000440857.1
DALRD3
DALR anticodon binding domain containing 3
chr10_-_62149433 0.288 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr16_+_71929397 0.287 ENST00000537613.1
ENST00000424485.2
ENST00000606369.1
ENST00000329908.8
ENST00000538850.1
ENST00000541918.1
ENST00000534994.1
ENST00000378798.5
ENST00000539186.1
IST1








increased sodium tolerance 1 homolog (yeast)








chr12_-_56122426 0.284 ENST00000551173.1
CD63
CD63 molecule
chr15_-_42749711 0.282 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
ZNF106


zinc finger protein 106


chr9_+_2159850 0.282 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_154178520 0.281 ENST00000433687.1
TRIM2
tripartite motif containing 2
chr12_+_122667658 0.281 ENST00000339777.4
ENST00000425921.1
LRRC43

leucine rich repeat containing 43

chr12_-_123752624 0.276 ENST00000542174.1
ENST00000535796.1
CDK2AP1

cyclin-dependent kinase 2 associated protein 1

chr19_+_50084561 0.276 ENST00000246794.5
PRRG2
proline rich Gla (G-carboxyglutamic acid) 2
chr2_-_148778323 0.275 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4



origin recognition complex, subunit 4



chr2_+_137523086 0.272 ENST00000409968.1
THSD7B
thrombospondin, type I, domain containing 7B
chr8_-_135522425 0.271 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr3_+_32147997 0.268 ENST00000282541.5
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr19_-_46285646 0.268 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr17_-_38083843 0.264 ENST00000304046.2
ENST00000579695.1
ORMDL3

ORM1-like 3 (S. cerevisiae)

chr17_+_26800296 0.263 ENST00000444914.3
ENST00000314669.5
SLC13A2

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2

chr1_-_33647267 0.263 ENST00000291416.5
TRIM62
tripartite motif containing 62
chr2_+_179149636 0.260 ENST00000409631.1
OSBPL6
oxysterol binding protein-like 6
chr17_-_26989136 0.260 ENST00000247020.4
SDF2
stromal cell-derived factor 2
chr6_-_133055815 0.259 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3






vanin 3






chr17_+_7461849 0.258 ENST00000338784.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr19_+_1041212 0.256 ENST00000433129.1
ABCA7
ATP-binding cassette, sub-family A (ABC1), member 7
chr6_-_31697563 0.256 ENST00000375789.2
ENST00000416410.1
DDAH2

dimethylarginine dimethylaminohydrolase 2

chr4_-_140223670 0.255 ENST00000394228.1
ENST00000539387.1
NDUFC1

NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa

chr10_+_88428206 0.253 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LDB3


LIM domain binding 3


chr1_-_38273840 0.253 ENST00000373044.2
YRDC
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr21_-_34185989 0.248 ENST00000487113.1
ENST00000382373.4
C21orf62

chromosome 21 open reading frame 62

chr17_-_80275466 0.246 ENST00000312648.3
CD7
CD7 molecule
chr10_+_102790980 0.245 ENST00000393459.1
ENST00000224807.5
SFXN3

sideroflexin 3

chr6_-_19804973 0.245 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2


RP4-625H18.2


chr1_-_68915610 0.244 ENST00000262340.5
RPE65
retinal pigment epithelium-specific protein 65kDa
chr17_+_73521763 0.240 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
LLGL2




lethal giant larvae homolog 2 (Drosophila)





Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.5 2.0 GO:0018032 protein amidation(GO:0018032)
0.4 1.2 GO:0021524 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913)
0.4 3.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.4 1.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3 2.9 GO:0015889 cobalamin transport(GO:0015889)
0.3 3.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.3 0.8 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.2 1.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 0.8 GO:2001293 fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.2 1.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.2 2.1 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.2 1.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 0.5 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.2 0.8 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.5 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.1 0.5 GO:0002086 diaphragm contraction(GO:0002086)
0.1 0.4 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.1 0.4 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 2.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.3 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.5 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.1 0.7 GO:0023021 termination of signal transduction(GO:0023021)
0.1 1.1 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 1.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 0.3 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.1 1.9 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.3 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 1.1 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.6 GO:0051604 protein maturation(GO:0051604)
0.1 0.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.8 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.2 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 1.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.3 GO:0035936 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.1 0.4 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.2 GO:1902908 regulation of melanosome transport(GO:1902908)
0.1 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.1 0.2 GO:0051685 maintenance of ER location(GO:0051685)
0.0 0.2 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.0 0.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.4 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.2 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.5 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.2 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 2.5 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.7 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.8 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.2 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.9 GO:0002467 germinal center formation(GO:0002467)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.5 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.3 GO:0032869 response to insulin(GO:0032868) cellular response to insulin stimulus(GO:0032869)
0.0 3.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0070253 somatostatin secretion(GO:0070253)
0.0 0.1 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.1 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 3.3 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 1.0 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.2 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.2 GO:0001554 luteolysis(GO:0001554)
0.0 0.7 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 1.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.6 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.8 GO:0010842 retina layer formation(GO:0010842)
0.0 0.4 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0 0.6 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.3 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 1.7 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 1.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.5 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.3 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 1.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.0 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.0 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.5 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.1 GO:0019827 stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727)
0.0 0.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.0 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.0 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.3 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:0044597 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.0 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 0.3 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.0 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.2 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.4 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.1 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) histone H2A K63-linked ubiquitination(GO:0070535) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.3 2.9 GO:0097427 microtubule bundle(GO:0097427)
0.2 1.7 GO:0044294 dendritic growth cone(GO:0044294)
0.2 0.5 GO:0072534 perineuronal net(GO:0072534)
0.1 1.0 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.7 GO:0097433 dense body(GO:0097433)
0.1 0.5 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 4.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.9 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 1.0 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 4.4 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 0.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701) junctional membrane complex(GO:0030314)
0.0 0.8 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.6 GO:0043235 receptor complex(GO:0043235)
0.0 1.3 GO:0036126 sperm flagellum(GO:0036126)
0.0 3.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 2.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.0 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 1.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.0 GO:0034704 calcium channel complex(GO:0034704)
0.0 1.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0044455 mitochondrial membrane part(GO:0044455)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.5 2.0 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.3 0.9 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.3 3.0 GO:0031419 cobalamin binding(GO:0031419)
0.3 0.8 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 1.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 1.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 0.5 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 1.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.9 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.3 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.4 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 2.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 2.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.3 GO:0090541 MIT domain binding(GO:0090541)
0.1 1.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.3 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 1.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.5 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.5 GO:0031013 troponin I binding(GO:0031013)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.2 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.1 0.7 GO:0038132 neuregulin binding(GO:0038132)
0.1 1.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 1.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 1.4 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.2 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 1.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.3 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 1.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 1.8 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0005537 mannose binding(GO:0005537) mannosidase activity(GO:0015923)
0.0 4.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.4 GO:0015197 peptide transporter activity(GO:0015197)
0.0 1.0 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 1.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 1.3 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.0 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.0 0.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.3 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 0.9 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.2 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.0 1.2 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 0.8 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.5 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.8 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 0.2 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.9 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.9 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.4 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.1 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.7 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.7 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.0 1.2 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.7 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis