Motif ID: TFEC_MITF_ARNTL_BHLHE41

Z-value: 0.660


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
BHLHE41hg19_v2_chr12_-_26278030_262780600.433.8e-02Click!
MITFhg19_v2_chr3_+_69985792_69985874-0.331.2e-01Click!
ARNTLhg19_v2_chr11_+_13299186_13299432-0.262.1e-01Click!
TFEChg19_v2_chr7_-_115670804_115670867,
hg19_v2_chr7_-_115608304_115608352
-0.029.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of TFEC_MITF_ARNTL_BHLHE41

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_67159416 2.392 ENST00000307980.2
ENST00000544620.1
RAD9A

RAD9 homolog A (S. pombe)

chr1_-_42921915 1.910 ENST00000372565.3
ENST00000433602.2
ZMYND12

zinc finger, MYND-type containing 12

chrY_+_22918021 1.648 ENST00000288666.5
RPS4Y2
ribosomal protein S4, Y-linked 2
chrY_+_2709527 1.529 ENST00000250784.8
RPS4Y1
ribosomal protein S4, Y-linked 1
chr3_-_19988462 1.471 ENST00000344838.4
EFHB
EF-hand domain family, member B
chrY_+_2709906 1.354 ENST00000430575.1
RPS4Y1
ribosomal protein S4, Y-linked 1
chr17_+_72270380 1.300 ENST00000582036.1
ENST00000307504.5
DNAI2

dynein, axonemal, intermediate chain 2

chr17_+_72270429 1.192 ENST00000311014.6
DNAI2
dynein, axonemal, intermediate chain 2
chrY_+_15016725 1.060 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chrY_+_15016013 1.027 ENST00000360160.4
ENST00000454054.1
DDX3Y

DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked

chr19_+_14544099 0.956 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
PKN1


protein kinase N1


chrX_-_34675391 0.944 ENST00000275954.3
TMEM47
transmembrane protein 47
chr1_+_154193325 0.924 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
UBAP2L





ubiquitin associated protein 2-like





chr19_-_49137762 0.802 ENST00000593500.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr19_-_10764509 0.793 ENST00000591501.1
ILF3-AS1
ILF3 antisense RNA 1 (head to head)
chr19_+_5720666 0.774 ENST00000381624.3
ENST00000381614.2
CATSPERD

catsper channel auxiliary subunit delta

chr8_+_75896731 0.746 ENST00000262207.4
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr19_-_49137790 0.743 ENST00000599385.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr6_+_151646800 0.741 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr19_-_11545920 0.729 ENST00000356392.4
ENST00000591179.1
CCDC151

coiled-coil domain containing 151

chrX_-_100914781 0.663 ENST00000431597.1
ENST00000458024.1
ENST00000413506.1
ENST00000440675.1
ENST00000328766.5
ENST00000356824.4
ARMCX2





armadillo repeat containing, X-linked 2





chr15_+_82555125 0.661 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B



family with sequence similarity 154, member B



chr10_+_99344071 0.641 ENST00000370647.4
ENST00000370646.4
HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

chr2_-_160143242 0.620 ENST00000359774.4
WDSUB1
WD repeat, sterile alpha motif and U-box domain containing 1
chr2_-_160143084 0.620 ENST00000409990.3
WDSUB1
WD repeat, sterile alpha motif and U-box domain containing 1
chr10_+_69644404 0.615 ENST00000212015.6
SIRT1
sirtuin 1
chr12_+_93964746 0.612 ENST00000536696.2
SOCS2
suppressor of cytokine signaling 2
chr7_+_36429424 0.611 ENST00000396068.2
ANLN
anillin, actin binding protein
chr12_-_111358372 0.609 ENST00000548438.1
ENST00000228841.8
MYL2

myosin, light chain 2, regulatory, cardiac, slow

chr2_-_160143059 0.605 ENST00000392796.3
WDSUB1
WD repeat, sterile alpha motif and U-box domain containing 1
chr7_+_36429409 0.605 ENST00000265748.2
ANLN
anillin, actin binding protein
chr2_-_160143158 0.599 ENST00000409124.1
ENST00000358147.4
WDSUB1

WD repeat, sterile alpha motif and U-box domain containing 1

chr17_-_7137582 0.577 ENST00000575756.1
ENST00000575458.1
DVL2

dishevelled segment polarity protein 2

chr2_+_240323439 0.556 ENST00000428471.1
ENST00000413029.1
AC062017.1

Uncharacterized protein

chr3_-_122512619 0.556 ENST00000383659.1
ENST00000306103.2
HSPBAP1

HSPB (heat shock 27kDa) associated protein 1

chr1_+_11866207 0.547 ENST00000312413.6
ENST00000346436.6
CLCN6

chloride channel, voltage-sensitive 6

chr5_-_133706695 0.547 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3





cyclin-dependent kinase-like 3





chr10_+_101542462 0.523 ENST00000370449.4
ENST00000370434.1
ABCC2

ATP-binding cassette, sub-family C (CFTR/MRP), member 2

chr1_-_68962805 0.517 ENST00000370966.5
DEPDC1
DEP domain containing 1
chr1_-_68962782 0.497 ENST00000456315.2
DEPDC1
DEP domain containing 1
chr17_-_7137857 0.490 ENST00000005340.5
DVL2
dishevelled segment polarity protein 2
chrX_-_101397433 0.483 ENST00000372774.3
TCEAL6
transcription elongation factor A (SII)-like 6
chr11_+_118938485 0.461 ENST00000300793.6
VPS11
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr6_+_87865262 0.460 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292



zinc finger protein 292



chr3_+_134204551 0.458 ENST00000332047.5
ENST00000354446.3
CEP63

centrosomal protein 63kDa

chr1_-_26233423 0.443 ENST00000357865.2
STMN1
stathmin 1
chr20_-_2821271 0.440 ENST00000448755.1
ENST00000360652.2
PCED1A

PC-esterase domain containing 1A

chr2_-_220108309 0.438 ENST00000409640.1
GLB1L
galactosidase, beta 1-like
chr4_+_39184024 0.432 ENST00000399820.3
ENST00000509560.1
ENST00000512112.1
ENST00000288634.7
ENST00000506503.1
WDR19




WD repeat domain 19




chr15_-_72668185 0.426 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
HEXA



hexosaminidase A (alpha polypeptide)



chr18_+_9136758 0.424 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ANKRD12


ankyrin repeat domain 12


chr10_-_25305011 0.422 ENST00000331161.4
ENST00000376363.1
ENKUR

enkurin, TRPC channel interacting protein

chr20_-_2821756 0.420 ENST00000356872.3
ENST00000439542.1
PCED1A

PC-esterase domain containing 1A

chr3_+_134205000 0.414 ENST00000512894.1
ENST00000513612.2
ENST00000606977.1
CEP63


centrosomal protein 63kDa


chr3_+_134204881 0.410 ENST00000511574.1
ENST00000337090.3
ENST00000383229.3
CEP63


centrosomal protein 63kDa


chr16_-_88923285 0.405 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
GALNS



galactosamine (N-acetyl)-6-sulfate sulfatase



chr1_-_27226928 0.403 ENST00000361720.5
GPATCH3
G patch domain containing 3
chr22_-_42342692 0.396 ENST00000404067.1
ENST00000402338.1
CENPM

centromere protein M

chr16_+_15737124 0.391 ENST00000396355.1
ENST00000396353.2
NDE1

nudE neurodevelopment protein 1

chr2_+_46926048 0.391 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr9_-_90589586 0.381 ENST00000325303.8
ENST00000375883.3
CDK20

cyclin-dependent kinase 20

chr14_+_77564440 0.375 ENST00000361786.2
ENST00000555437.1
ENST00000555611.1
ENST00000554658.1
KIAA1737



CLOCK-interacting pacemaker



chr18_+_56530794 0.373 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
ZNF532


zinc finger protein 532


chr5_+_78532003 0.372 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr12_+_122356488 0.366 ENST00000397454.2
WDR66
WD repeat domain 66
chr17_+_17876127 0.366 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
LRRC48









leucine rich repeat containing 48









chr6_-_33385854 0.362 ENST00000488478.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr12_+_12878829 0.359 ENST00000326765.6
APOLD1
apolipoprotein L domain containing 1
chr9_-_90589402 0.358 ENST00000375871.4
ENST00000605159.1
ENST00000336654.5
CDK20


cyclin-dependent kinase 20


chr22_-_42343117 0.358 ENST00000407253.3
ENST00000215980.5
CENPM

centromere protein M

chr3_-_45883558 0.356 ENST00000445698.1
ENST00000296135.6
LZTFL1

leucine zipper transcription factor-like 1

chr16_+_84178874 0.351 ENST00000378553.5
DNAAF1
dynein, axonemal, assembly factor 1
chr16_+_31044413 0.348 ENST00000394998.1
STX4
syntaxin 4
chr15_-_72668805 0.346 ENST00000268097.5
HEXA
hexosaminidase A (alpha polypeptide)
chr15_+_41913690 0.339 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr9_-_79307096 0.334 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
PRUNE2


prune homolog 2 (Drosophila)


chr3_-_134204815 0.328 ENST00000514612.1
ENST00000510994.1
ENST00000354910.5
ANAPC13


anaphase promoting complex subunit 13


chr3_+_130745769 0.322 ENST00000412440.2
NEK11
NIMA-related kinase 11
chr17_+_79935464 0.322 ENST00000581647.1
ENST00000580534.1
ENST00000579684.1
ASPSCR1


alveolar soft part sarcoma chromosome region, candidate 1


chr6_+_151561506 0.320 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr19_+_1275917 0.318 ENST00000469144.1
C19orf24
chromosome 19 open reading frame 24
chr4_+_128651530 0.317 ENST00000281154.4
SLC25A31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr16_-_23160591 0.317 ENST00000219689.7
USP31
ubiquitin specific peptidase 31
chr7_+_116593433 0.317 ENST00000323984.3
ENST00000393449.1
ST7

suppression of tumorigenicity 7

chr7_+_116593568 0.316 ENST00000446490.1
ST7
suppression of tumorigenicity 7
chr6_-_33385655 0.316 ENST00000440279.3
ENST00000607266.1
CUTA

cutA divalent cation tolerance homolog (E. coli)

chr8_+_17780346 0.314 ENST00000325083.8
PCM1
pericentriolar material 1
chr17_-_35969409 0.312 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
SYNRG







synergin, gamma







chr9_-_34048873 0.312 ENST00000449054.1
ENST00000379239.4
ENST00000539807.1
ENST00000379238.1
ENST00000418786.2
ENST00000360802.1
ENST00000412543.1
UBAP2






ubiquitin associated protein 2






chr6_-_33385823 0.311 ENST00000494751.1
ENST00000374496.3
CUTA

cutA divalent cation tolerance homolog (E. coli)

chr22_+_35776828 0.308 ENST00000216117.8
HMOX1
heme oxygenase (decycling) 1
chr1_-_204329013 0.305 ENST00000272203.3
ENST00000414478.1
PLEKHA6

pleckstrin homology domain containing, family A member 6

chr7_-_155089251 0.304 ENST00000609974.1
AC144652.1
AC144652.1
chr6_-_84937314 0.301 ENST00000257766.4
ENST00000403245.3
KIAA1009

KIAA1009

chr17_+_62503147 0.298 ENST00000553412.1
CEP95
centrosomal protein 95kDa
chr16_+_2570340 0.295 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
AMDHD2





amidohydrolase domain containing 2





chr14_-_20929624 0.292 ENST00000398020.4
ENST00000250489.4
TMEM55B

transmembrane protein 55B

chr1_+_17248418 0.287 ENST00000375541.5
CROCC
ciliary rootlet coiled-coil, rootletin
chr19_-_41256207 0.287 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
C19orf54



chromosome 19 open reading frame 54



chr8_-_103425047 0.286 ENST00000520539.1
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr18_-_29522989 0.284 ENST00000582539.1
ENST00000283351.4
ENST00000582513.1
TRAPPC8


trafficking protein particle complex 8


chr19_-_5719860 0.283 ENST00000590729.1
LONP1
lon peptidase 1, mitochondrial
chr12_-_123849374 0.282 ENST00000602398.1
ENST00000602750.1
SBNO1

strawberry notch homolog 1 (Drosophila)

chrX_-_102531717 0.277 ENST00000372680.1
TCEAL5
transcription elongation factor A (SII)-like 5
chr2_+_187558698 0.272 ENST00000304698.5
FAM171B
family with sequence similarity 171, member B
chr6_-_43337180 0.271 ENST00000318149.3
ENST00000361428.2
ZNF318

zinc finger protein 318

chr17_+_42977122 0.270 ENST00000417826.2
ENST00000412523.2
ENST00000331733.4
CCDC103
FAM187A

coiled-coil domain containing 103
family with sequence similarity 187, member A

chr1_-_166845515 0.269 ENST00000367874.4
TADA1
transcriptional adaptor 1
chr2_+_27309605 0.269 ENST00000260599.6
ENST00000260598.5
ENST00000429697.1
KHK


ketohexokinase (fructokinase)


chr16_+_31044812 0.269 ENST00000313843.3
STX4
syntaxin 4
chr5_-_121413974 0.268 ENST00000231004.4
LOX
lysyl oxidase
chr3_-_189840223 0.267 ENST00000427335.2
LEPREL1
leprecan-like 1
chr17_+_79935418 0.266 ENST00000306729.7
ENST00000306739.4
ASPSCR1

alveolar soft part sarcoma chromosome region, candidate 1

chr1_-_154928562 0.263 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1




pre-B-cell leukemia homeobox interacting protein 1




chr8_+_67039278 0.261 ENST00000276573.7
ENST00000350034.4
TRIM55

tripartite motif containing 55

chr5_+_172483347 0.260 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREBRF



CREB3 regulatory factor



chr9_-_100684845 0.257 ENST00000375119.3
C9orf156
chromosome 9 open reading frame 156
chr11_+_95523823 0.257 ENST00000538658.1
CEP57
centrosomal protein 57kDa
chr6_-_33385870 0.252 ENST00000488034.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr2_-_197036289 0.251 ENST00000263955.4
STK17B
serine/threonine kinase 17b
chr10_-_32217717 0.248 ENST00000396144.4
ENST00000375245.4
ENST00000344936.2
ENST00000375250.5
ARHGAP12



Rho GTPase activating protein 12



chr19_-_11688500 0.247 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr16_+_5083950 0.247 ENST00000588623.1
ALG1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr17_-_7197881 0.246 ENST00000007699.5
YBX2
Y box binding protein 2
chr19_+_4007644 0.243 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chrY_-_15591485 0.242 ENST00000382896.4
ENST00000537580.1
ENST00000540140.1
ENST00000545955.1
ENST00000538878.1
UTY




ubiquitously transcribed tetratricopeptide repeat containing, Y-linked




chr2_+_46926326 0.241 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr11_-_113746277 0.240 ENST00000003302.4
ENST00000545540.1
USP28

ubiquitin specific peptidase 28

chr2_+_114384806 0.240 ENST00000393167.3
ENST00000409842.1
ENST00000413545.1
ENST00000393165.3
ENST00000393166.3
ENST00000409875.1
ENST00000376439.3
RABL2A






RAB, member of RAS oncogene family-like 2A






chr2_-_133427767 0.239 ENST00000397463.2
LYPD1
LY6/PLAUR domain containing 1
chrX_+_102883887 0.238 ENST00000372625.3
ENST00000372624.3
TCEAL1

transcription elongation factor A (SII)-like 1

chr17_-_5015129 0.238 ENST00000575898.1
ENST00000416429.2
ZNF232

zinc finger protein 232

chr22_-_51222070 0.233 ENST00000395593.3
ENST00000395598.3
ENST00000435118.1
ENST00000395591.1
ENST00000395595.3
RABL2B




RAB, member of RAS oncogene family-like 2B




chr9_-_138391692 0.232 ENST00000429260.2
C9orf116
chromosome 9 open reading frame 116
chr6_-_33385902 0.232 ENST00000374500.5
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr21_-_46330545 0.231 ENST00000320216.6
ENST00000397852.1
ITGB2

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

chr3_+_130745688 0.228 ENST00000510769.1
ENST00000429253.2
ENST00000356918.4
ENST00000510688.1
ENST00000511262.1
ENST00000383366.4
NEK11





NIMA-related kinase 11





chr11_+_7534999 0.228 ENST00000528947.1
ENST00000299492.4
PPFIBP2

PTPRF interacting protein, binding protein 2 (liprin beta 2)

chr17_-_30185946 0.226 ENST00000579741.1
COPRS
coordinator of PRMT5, differentiation stimulator
chrX_+_102469997 0.225 ENST00000372695.5
ENST00000372691.3
BEX4

brain expressed, X-linked 4

chr8_+_133787586 0.224 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHF20L1


PHD finger protein 20-like 1


chr22_+_31003133 0.223 ENST00000405742.3
TCN2
transcobalamin II
chr2_-_182545603 0.223 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr12_+_93964158 0.223 ENST00000549206.1
SOCS2
suppressor of cytokine signaling 2
chr1_-_3447967 0.221 ENST00000294599.4
MEGF6
multiple EGF-like-domains 6
chr1_+_150254936 0.218 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51


chromosome 1 open reading frame 51


chr19_+_50016411 0.215 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT


Fc fragment of IgG, receptor, transporter, alpha


chr17_+_58755184 0.215 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3


breast carcinoma amplified sequence 3


chr2_-_220083671 0.215 ENST00000439002.2
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr9_+_133971863 0.214 ENST00000372309.3
AIF1L
allograft inflammatory factor 1-like
chr16_+_5121814 0.214 ENST00000262374.5
ENST00000586840.1
ALG1

ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase

chr1_-_207119738 0.212 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr3_-_48057890 0.212 ENST00000434267.1
MAP4
microtubule-associated protein 4
chr17_+_26684604 0.210 ENST00000292114.3
ENST00000509083.1
TMEM199

transmembrane protein 199

chr14_-_94443105 0.210 ENST00000555019.1
ASB2
ankyrin repeat and SOCS box containing 2
chr19_-_45004556 0.209 ENST00000587047.1
ENST00000391956.4
ENST00000221327.4
ENST00000586637.1
ENST00000591064.1
ENST00000592529.1
ZNF180





zinc finger protein 180





chr14_-_20923195 0.209 ENST00000206542.4
OSGEP
O-sialoglycoprotein endopeptidase
chr19_-_5340730 0.208 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
PTPRS




protein tyrosine phosphatase, receptor type, S




chr7_+_116593292 0.206 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
ST7


suppression of tumorigenicity 7


chr22_+_31002779 0.204 ENST00000215838.3
TCN2
transcobalamin II
chr7_-_30029367 0.203 ENST00000242059.5
SCRN1
secernin 1
chr2_-_220083692 0.203 ENST00000265316.3
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr7_+_97361218 0.201 ENST00000319273.5
TAC1
tachykinin, precursor 1
chr11_-_113746212 0.200 ENST00000537642.1
ENST00000537706.1
ENST00000544750.1
ENST00000260188.5
ENST00000540925.1
USP28




ubiquitin specific peptidase 28




chr19_+_45504688 0.200 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB


v-rel avian reticuloendotheliosis viral oncogene homolog B


chr15_+_44084040 0.199 ENST00000249786.4
SERF2
small EDRK-rich factor 2
chr2_-_40006357 0.198 ENST00000505747.1
THUMPD2
THUMP domain containing 2
chr19_-_5720123 0.197 ENST00000587365.1
ENST00000585374.1
ENST00000593119.1
LONP1


lon peptidase 1, mitochondrial


chr7_-_30029574 0.197 ENST00000426154.1
ENST00000421434.1
ENST00000434476.2
SCRN1


secernin 1


chrX_-_9734004 0.195 ENST00000467482.1
ENST00000380929.2
GPR143

G protein-coupled receptor 143

chr2_+_85981008 0.193 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr15_+_89182178 0.193 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr22_-_51222042 0.193 ENST00000354869.3
ENST00000395590.1
RABL2B

RAB, member of RAS oncogene family-like 2B

chr9_+_33290491 0.191 ENST00000379540.3
ENST00000379521.4
ENST00000318524.6
NFX1


nuclear transcription factor, X-box binding 1


chr5_+_68463043 0.191 ENST00000508407.1
ENST00000505500.1
CCNB1

cyclin B1

chr4_-_89978299 0.190 ENST00000511976.1
ENST00000509094.1
ENST00000264344.5
ENST00000515600.1
FAM13A



family with sequence similarity 13, member A



chr1_-_154193091 0.189 ENST00000362076.4
ENST00000350592.3
ENST00000368516.1
C1orf43


chromosome 1 open reading frame 43


chr6_+_138188551 0.188 ENST00000237289.4
ENST00000433680.1
TNFAIP3

tumor necrosis factor, alpha-induced protein 3

chrX_-_13835147 0.186 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr15_-_31393910 0.185 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
TRPM1


transient receptor potential cation channel, subfamily M, member 1


chr16_+_699319 0.185 ENST00000549091.1
ENST00000293879.4
WDR90

WD repeat domain 90

chr11_+_9595180 0.184 ENST00000450114.2
WEE1
WEE1 G2 checkpoint kinase
chr17_-_76124711 0.184 ENST00000306591.7
ENST00000590602.1
TMC6

transmembrane channel-like 6

chr1_+_183605200 0.184 ENST00000304685.4
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr1_-_217250231 0.183 ENST00000493748.1
ENST00000463665.1
ESRRG

estrogen-related receptor gamma

chr7_+_73242069 0.182 ENST00000435050.1
CLDN4
claudin 4
chr7_-_47621736 0.182 ENST00000311160.9
TNS3
tensin 3
chr15_+_89181974 0.182 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr12_+_133613878 0.181 ENST00000392319.2
ENST00000543758.1
ZNF84

zinc finger protein 84

chr11_+_65479702 0.180 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
KAT5





K(lysine) acetyltransferase 5





chr1_+_111889212 0.179 ENST00000369737.4
PIFO
primary cilia formation
chr11_-_19263145 0.178 ENST00000532666.1
ENST00000527884.1
E2F8

E2F transcription factor 8

chr19_-_12886327 0.178 ENST00000397668.3
ENST00000587178.1
ENST00000264827.5
HOOK2


hook microtubule-tethering protein 2


chr1_+_42921761 0.177 ENST00000372562.1
PPCS
phosphopantothenoylcysteine synthetase
chr12_+_28343365 0.176 ENST00000545336.1
CCDC91
coiled-coil domain containing 91
chr12_+_113796347 0.175 ENST00000545182.2
ENST00000280800.3
PLBD2

phospholipase B domain containing 2

chr14_+_96858433 0.174 ENST00000267584.4
AK7
adenylate kinase 7
chr6_+_7590413 0.173 ENST00000342415.5
SNRNP48
small nuclear ribonucleoprotein 48kDa (U11/U12)
chr8_-_72268968 0.173 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chrX_+_128913906 0.172 ENST00000356892.3
SASH3
SAM and SH3 domain containing 3

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1904170 regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.4 2.6 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.3 1.1 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 0.6 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.2 0.6 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.2 0.6 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.2 0.6 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 1.3 GO:0098535 de novo centriole assembly(GO:0098535)
0.2 3.8 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 0.5 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.2 1.0 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.2 0.9 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.4 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.1 0.4 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.3 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.1 0.4 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.3 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.3 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.3 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.3 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.3 GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.5 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.3 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.1 0.6 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 1.0 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.3 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.2 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.2 GO:0009386 translational attenuation(GO:0009386)
0.1 0.1 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.1 0.2 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.6 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.2 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) positive regulation of apoptotic DNA fragmentation(GO:1902512) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 1.0 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.1 GO:0034059 response to anoxia(GO:0034059)
0.1 0.2 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.1 0.3 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 0.2 GO:1902908 regulation of melanosome transport(GO:1902908)
0.0 0.6 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.5 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.3 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.2 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.4 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0071284 detoxification of copper ion(GO:0010273) cellular response to lead ion(GO:0071284) stress response to copper ion(GO:1990169)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.0 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.2 GO:2000301 regulation of intracellular transport of viral material(GO:1901252) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.4 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.3 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.2 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.1 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.1 GO:0098502 DNA dephosphorylation(GO:0098502)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.2 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 1.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.4 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.8 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.2 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.0 GO:1901856 negative regulation of cellular respiration(GO:1901856) negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.2 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.8 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.6 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.1 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.0 0.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.5 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.1 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.0 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.8 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.0 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.1 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
0.0 2.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.3 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.0 GO:1901524 regulation of macromitophagy(GO:1901524)
0.0 0.5 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.0 GO:0015993 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0044254 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.0 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.5 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.0 GO:0072229 isoleucine catabolic process(GO:0006550) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.0 0.1 GO:1904350 regulation of protein catabolic process in the vacuole(GO:1904350) positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.0 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.2 GO:2000615 regulation of histone H3-K9 acetylation(GO:2000615)
0.0 0.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0007501 mesodermal cell fate specification(GO:0007501)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.2 1.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 2.5 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.6 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.4 GO:0001534 radial spoke(GO:0001534)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.8 GO:0036128 CatSper complex(GO:0036128)
0.1 0.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.2 GO:0035841 new growing cell tip(GO:0035841)
0.1 0.6 GO:0000322 storage vacuole(GO:0000322)
0.1 0.2 GO:0019034 viral replication complex(GO:0019034)
0.1 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.0 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 3.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.6 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0097447 dendritic tree(GO:0097447)
0.0 0.5 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.2 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.5 GO:0000242 pericentriolar material(GO:0000242)
0.0 1.3 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 2.1 GO:0005814 centriole(GO:0005814)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.0 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:1990742 microvesicle(GO:1990742)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 0.0 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 0.7 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 0.6 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.2 0.5 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 1.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 0.6 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 0.6 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.8 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.4 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.1 0.4 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 2.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.6 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.8 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 1.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 4.3 GO:0019843 rRNA binding(GO:0019843)
0.1 0.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.2 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702) oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.2 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 1.6 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0035240 dopamine binding(GO:0035240)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.0 0.0 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) polynucleotide phosphatase activity(GO:0098518)
0.0 0.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.2 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.0 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.4 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.0 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.7 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 2.6 PID_ATM_PATHWAY ATM pathway
0.0 1.1 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 0.6 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 1.1 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.6 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.1 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.2 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.1 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.2 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.0 PID_IL2_1PATHWAY IL2-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 2.3 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.7 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 2.6 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.0 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.9 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.8 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.0 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.8 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.0 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.9 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development