Motif ID: TLX2

Z-value: 0.786


Transcription factors associated with TLX2:

Gene SymbolEntrez IDGene Name
TLX2 ENSG00000115297.9 TLX2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TLX2hg19_v2_chr2_+_74741569_747416200.125.8e-01Click!


Activity profile for motif TLX2.

activity profile for motif TLX2


Sorted Z-values histogram for motif TLX2

Sorted Z-values for motif TLX2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_102928009 3.753 ENST00000404917.2
ENST00000447231.1
IL1RL1

interleukin 1 receptor-like 1

chr8_+_86376081 2.897 ENST00000285379.5
CA2
carbonic anhydrase II
chr14_+_54863739 2.351 ENST00000541304.1
CDKN3
cyclin-dependent kinase inhibitor 3
chr2_+_10262857 2.156 ENST00000304567.5
RRM2
ribonucleotide reductase M2
chr14_+_54863667 2.151 ENST00000335183.6
CDKN3
cyclin-dependent kinase inhibitor 3
chr14_+_54863682 2.142 ENST00000543789.2
ENST00000442975.2
ENST00000458126.2
ENST00000556102.2
CDKN3



cyclin-dependent kinase inhibitor 3



chr1_-_17304771 1.958 ENST00000375534.3
MFAP2
microfibrillar-associated protein 2
chr4_+_17812525 1.931 ENST00000251496.2
NCAPG
non-SMC condensin I complex, subunit G
chr11_+_69924639 1.702 ENST00000538023.1
ENST00000398543.2
ANO1

anoctamin 1, calcium activated chloride channel

chr1_+_152881014 1.643 ENST00000368764.3
ENST00000392667.2
IVL

involucrin

chr11_-_123065989 1.570 ENST00000448775.2
CLMP
CXADR-like membrane protein
chr1_+_152486950 1.543 ENST00000368790.3
CRCT1
cysteine-rich C-terminal 1
chr10_+_88718397 1.518 ENST00000372017.3
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr1_-_24469602 1.501 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr22_+_31477296 1.497 ENST00000426927.1
ENST00000440425.1
ENST00000358743.1
ENST00000347557.2
ENST00000333137.7
SMTN




smoothelin




chr10_+_88718314 1.417 ENST00000348795.4
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr6_+_24775641 1.393 ENST00000378054.2
ENST00000476555.1
GMNN

geminin, DNA replication inhibitor

chr10_-_90712520 1.294 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr3_+_121796697 1.279 ENST00000482356.1
ENST00000393627.2
CD86

CD86 molecule

chr2_-_190044480 1.230 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr19_+_676385 1.197 ENST00000166139.4
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr4_+_156680518 1.178 ENST00000513437.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr14_+_55034599 1.142 ENST00000392067.3
ENST00000357634.3
SAMD4A

sterile alpha motif domain containing 4A

chr7_+_155090271 1.137 ENST00000476756.1
INSIG1
insulin induced gene 1
chr19_-_11266471 1.122 ENST00000592540.1
SPC24
SPC24, NDC80 kinetochore complex component
chr2_-_72375167 1.110 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr3_+_121774202 1.090 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86



CD86 molecule



chr17_-_76899275 1.085 ENST00000322630.2
ENST00000586713.1
DDC8

Protein DDC8 homolog

chr12_-_99038732 1.074 ENST00000393042.3
ENST00000420861.1
ENST00000299157.4
ENST00000342502.2
IKBIP



IKBKB interacting protein



chr4_+_156680143 1.073 ENST00000505154.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr17_-_39211463 1.058 ENST00000542910.1
ENST00000398477.1
KRTAP2-2

keratin associated protein 2-2

chr3_-_42744312 1.047 ENST00000416756.1
ENST00000441594.1
HHATL

hedgehog acyltransferase-like

chr4_+_1873100 1.011 ENST00000508803.1
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr10_-_75401500 1.010 ENST00000359322.4
MYOZ1
myozenin 1
chr9_+_35673853 1.009 ENST00000378357.4
CA9
carbonic anhydrase IX
chr19_+_47104553 1.005 ENST00000598871.1
ENST00000594523.1
CALM3

calmodulin 3 (phosphorylase kinase, delta)

chr1_+_86889769 1.003 ENST00000370565.4
CLCA2
chloride channel accessory 2
chr14_+_65171315 0.978 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr4_+_156680153 0.977 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
GUCY1B3




guanylate cyclase 1, soluble, beta 3




chr20_-_1373606 0.944 ENST00000381715.1
ENST00000439640.2
ENST00000381719.3
FKBP1A


FK506 binding protein 1A, 12kDa


chr8_+_22423219 0.931 ENST00000523965.1
ENST00000521554.1
SORBS3

sorbin and SH3 domain containing 3

chr2_+_192543153 0.928 ENST00000425611.2
NABP1
nucleic acid binding protein 1
chr1_+_151030234 0.870 ENST00000368921.3
MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr14_-_57272366 0.867 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2


orthodenticle homeobox 2


chr14_+_65171099 0.848 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr9_+_36572851 0.847 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK







maternal embryonic leucine zipper kinase







chr21_-_16437126 0.844 ENST00000318948.4
NRIP1
nuclear receptor interacting protein 1
chr21_-_16437255 0.841 ENST00000400199.1
ENST00000400202.1
NRIP1

nuclear receptor interacting protein 1

chr8_+_26435359 0.840 ENST00000311151.5
DPYSL2
dihydropyrimidinase-like 2
chr9_+_75263565 0.838 ENST00000396237.3
TMC1
transmembrane channel-like 1
chr21_-_38639601 0.835 ENST00000539844.1
ENST00000476950.1
ENST00000399001.1
DSCR3


Down syndrome critical region gene 3


chr10_+_124030819 0.824 ENST00000260723.4
ENST00000368994.2
BTBD16

BTB (POZ) domain containing 16

chr10_-_103347883 0.819 ENST00000339310.3
ENST00000370158.3
ENST00000299206.4
ENST00000456836.2
ENST00000413344.1
ENST00000429502.1
ENST00000430045.1
ENST00000370172.1
ENST00000436284.2
ENST00000370162.3
POLL









polymerase (DNA directed), lambda









chr8_+_27182862 0.815 ENST00000521164.1
ENST00000346049.5
PTK2B

protein tyrosine kinase 2 beta

chr10_-_33623564 0.812 ENST00000374875.1
ENST00000374822.4
NRP1

neuropilin 1

chr10_+_76871229 0.805 ENST00000372690.3
SAMD8
sterile alpha motif domain containing 8
chr15_-_82555000 0.805 ENST00000557844.1
ENST00000359445.3
ENST00000268206.7
EFTUD1


elongation factor Tu GTP binding domain containing 1


chr2_+_113403434 0.802 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr8_+_27183033 0.792 ENST00000420218.2
PTK2B
protein tyrosine kinase 2 beta
chr5_-_159797627 0.790 ENST00000393975.3
C1QTNF2
C1q and tumor necrosis factor related protein 2
chr9_+_139847347 0.786 ENST00000371632.3
LCN12
lipocalin 12
chr11_+_35160709 0.768 ENST00000415148.2
ENST00000433354.2
ENST00000449691.2
ENST00000437706.2
ENST00000360158.4
ENST00000428726.2
ENST00000526669.2
ENST00000433892.2
ENST00000278386.6
ENST00000434472.2
ENST00000352818.4
ENST00000442151.2
CD44











CD44 molecule (Indian blood group)











chr19_-_11688500 0.761 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr1_+_16083154 0.737 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr1_-_6526192 0.736 ENST00000377782.3
ENST00000351959.5
ENST00000356876.3
TNFRSF25


tumor necrosis factor receptor superfamily, member 25


chr19_-_11688447 0.733 ENST00000590420.1
ACP5
acid phosphatase 5, tartrate resistant
chr1_+_119957554 0.728 ENST00000543831.1
ENST00000433745.1
ENST00000369416.3
HSD3B2


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2


chr6_-_39290316 0.726 ENST00000425054.2
ENST00000373227.4
ENST00000373229.5
ENST00000437525.2
KCNK16



potassium channel, subfamily K, member 16



chr13_+_109248500 0.723 ENST00000356711.2
MYO16
myosin XVI
chr2_-_224702257 0.721 ENST00000409375.1
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr12_+_6602517 0.720 ENST00000315579.5
ENST00000539714.1
NCAPD2

non-SMC condensin I complex, subunit D2

chr1_-_22263790 0.717 ENST00000374695.3
HSPG2
heparan sulfate proteoglycan 2
chr2_-_224702270 0.702 ENST00000396654.2
ENST00000396653.2
ENST00000423110.1
ENST00000443700.1
AP1S3



adaptor-related protein complex 1, sigma 3 subunit



chr19_-_51512804 0.698 ENST00000594211.1
ENST00000376832.4
KLK9

kallikrein-related peptidase 9

chr16_+_11343475 0.693 ENST00000572173.1
RMI2
RecQ mediated genome instability 2
chr1_-_204135450 0.693 ENST00000272190.8
ENST00000367195.2
REN

renin

chr6_-_66417107 0.689 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS



eyes shut homolog (Drosophila)



chr2_-_224702201 0.687 ENST00000446015.2
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr16_-_88851618 0.674 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr1_-_6526167 0.668 ENST00000351748.3
ENST00000348333.3
TNFRSF25

tumor necrosis factor receptor superfamily, member 25

chr12_-_33049690 0.659 ENST00000070846.6
ENST00000340811.4
PKP2

plakophilin 2

chrX_+_46940254 0.632 ENST00000336169.3
RGN
regucalcin
chr1_-_156571254 0.619 ENST00000438976.2
ENST00000334588.7
ENST00000368232.4
ENST00000415314.2
GPATCH4



G patch domain containing 4



chr8_-_131455835 0.617 ENST00000518721.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr14_-_54955721 0.605 ENST00000554908.1
GMFB
glia maturation factor, beta
chr6_+_106546808 0.599 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr4_+_2814011 0.598 ENST00000502260.1
ENST00000435136.2
SH3BP2

SH3-domain binding protein 2

chr7_+_77469439 0.596 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2


putative homeodomain transcription factor 2


chr8_-_105601134 0.587 ENST00000276654.5
ENST00000424843.2
LRP12

low density lipoprotein receptor-related protein 12

chr19_-_59084647 0.578 ENST00000594234.1
ENST00000596039.1
MZF1

myeloid zinc finger 1

chr18_+_29077990 0.574 ENST00000261590.8
DSG2
desmoglein 2
chr4_-_165305086 0.572 ENST00000507270.1
ENST00000514618.1
ENST00000503008.1
MARCH1


membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase


chr19_+_2389784 0.572 ENST00000332578.3
TMPRSS9
transmembrane protease, serine 9
chr16_+_15744078 0.564 ENST00000396354.1
ENST00000570727.1
NDE1

nudE neurodevelopment protein 1

chr3_+_50192537 0.563 ENST00000002829.3
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr19_+_35783037 0.556 ENST00000361922.4
MAG
myelin associated glycoprotein
chr10_+_76871353 0.550 ENST00000542569.1
SAMD8
sterile alpha motif domain containing 8
chr20_+_42984330 0.550 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A



hepatocyte nuclear factor 4, alpha



chr20_+_56884752 0.547 ENST00000244040.3
RAB22A
RAB22A, member RAS oncogene family
chr3_+_50192499 0.546 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr15_-_34628951 0.539 ENST00000397707.2
ENST00000560611.1
SLC12A6

solute carrier family 12 (potassium/chloride transporter), member 6

chr19_+_35783047 0.536 ENST00000595791.1
ENST00000597035.1
ENST00000537831.2
MAG


myelin associated glycoprotein


chr19_+_39421556 0.536 ENST00000407800.2
ENST00000402029.3
MRPS12

mitochondrial ribosomal protein S12

chr10_+_76871454 0.530 ENST00000372687.4
SAMD8
sterile alpha motif domain containing 8
chr8_-_145018905 0.527 ENST00000398774.2
PLEC
plectin
chr11_+_65343494 0.526 ENST00000309295.4
ENST00000533237.1
EHBP1L1

EH domain binding protein 1-like 1

chr1_+_24645865 0.524 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr1_+_86046433 0.524 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr5_+_131409476 0.523 ENST00000296871.2
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr19_+_48216600 0.519 ENST00000263277.3
ENST00000538399.1
EHD2

EH-domain containing 2

chr19_+_35783028 0.516 ENST00000600291.1
ENST00000392213.3
MAG

myelin associated glycoprotein

chr4_+_169552748 0.516 ENST00000504519.1
ENST00000512127.1
PALLD

palladin, cytoskeletal associated protein

chr5_-_147162263 0.514 ENST00000333010.6
ENST00000265272.5
JAKMIP2

janus kinase and microtubule interacting protein 2

chr1_+_31769836 0.512 ENST00000344147.5
ENST00000373714.1
ENST00000546109.1
ENST00000422613.2
ZCCHC17



zinc finger, CCHC domain containing 17



chr11_+_62186498 0.512 ENST00000278282.2
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr1_+_24645807 0.512 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr1_+_24646002 0.511 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr12_+_71833756 0.511 ENST00000536515.1
ENST00000540815.2
LGR5

leucine-rich repeat containing G protein-coupled receptor 5

chr2_-_130939115 0.505 ENST00000441135.1
ENST00000339679.7
ENST00000426662.2
ENST00000443958.2
ENST00000351288.6
ENST00000453750.1
ENST00000452225.2
SMPD4






sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)






chr11_+_67195917 0.503 ENST00000524934.1
ENST00000539188.1
ENST00000312629.5
RPS6KB2


ribosomal protein S6 kinase, 70kDa, polypeptide 2


chr5_-_147162078 0.502 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2
chr11_-_93474645 0.497 ENST00000532455.1
TAF1D
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
chr12_-_95611149 0.496 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
FGD6


FYVE, RhoGEF and PH domain containing 6


chr2_+_17721920 0.493 ENST00000295156.4
VSNL1
visinin-like 1
chr4_-_69111401 0.491 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr3_+_101504200 0.489 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr16_-_28223166 0.481 ENST00000304658.5
XPO6
exportin 6
chr7_-_22539771 0.480 ENST00000406890.2
ENST00000424363.1
STEAP1B

STEAP family member 1B

chr6_-_43496605 0.476 ENST00000455285.2
XPO5
exportin 5
chr12_+_9144626 0.475 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr19_-_6767516 0.474 ENST00000245908.6
SH2D3A
SH2 domain containing 3A
chr1_-_151762943 0.471 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
TDRKH




tudor and KH domain containing




chr2_+_219433588 0.470 ENST00000295701.5
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr16_+_30075463 0.469 ENST00000562168.1
ENST00000569545.1
ALDOA

aldolase A, fructose-bisphosphate

chr14_-_67859422 0.468 ENST00000556532.1
PLEK2
pleckstrin 2
chr1_+_107683644 0.462 ENST00000370067.1
NTNG1
netrin G1
chr21_-_38639813 0.458 ENST00000309117.6
ENST00000398998.1
DSCR3

Down syndrome critical region gene 3

chr1_+_57320437 0.453 ENST00000361249.3
C8A
complement component 8, alpha polypeptide
chr16_-_3149278 0.449 ENST00000575108.1
ENST00000576483.1
ENST00000538082.2
ENST00000576985.1
ZSCAN10



zinc finger and SCAN domain containing 10



chr12_-_122240792 0.449 ENST00000541657.1
ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
RHOF
AC084018.1





ras homolog family member F (in filopodia)
AC084018.1





chr14_-_24610779 0.443 ENST00000560403.1
ENST00000419198.2
ENST00000216799.4
EMC9


ER membrane protein complex subunit 9


chr19_+_47104493 0.439 ENST00000291295.9
ENST00000597743.1
CALM3

calmodulin 3 (phosphorylase kinase, delta)

chr3_+_14716606 0.438 ENST00000253697.3
ENST00000435614.1
ENST00000412910.1
C3orf20


chromosome 3 open reading frame 20


chr16_+_31119615 0.434 ENST00000394950.3
ENST00000287507.3
ENST00000219794.6
ENST00000561755.1
BCKDK



branched chain ketoacid dehydrogenase kinase



chr1_-_32169920 0.423 ENST00000373672.3
ENST00000373668.3
COL16A1

collagen, type XVI, alpha 1

chr1_-_32169761 0.414 ENST00000271069.6
COL16A1
collagen, type XVI, alpha 1
chr8_+_38758737 0.412 ENST00000521746.1
ENST00000420274.1
PLEKHA2

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2

chr16_-_28222797 0.407 ENST00000569951.1
ENST00000565698.1
XPO6

exportin 6

chr15_+_81475047 0.407 ENST00000559388.1
IL16
interleukin 16
chr17_+_7211280 0.406 ENST00000419711.2
ENST00000571955.1
ENST00000573714.1
EIF5A


eukaryotic translation initiation factor 5A


chr12_+_56732658 0.405 ENST00000228534.4
IL23A
interleukin 23, alpha subunit p19
chr19_+_4402659 0.403 ENST00000301280.5
ENST00000585854.1
CHAF1A

chromatin assembly factor 1, subunit A (p150)

chr15_-_71055769 0.403 ENST00000539319.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr1_+_53068020 0.401 ENST00000361314.4
GPX7
glutathione peroxidase 7
chr5_-_16916624 0.400 ENST00000513882.1
MYO10
myosin X
chr3_+_63428752 0.399 ENST00000295894.5
SYNPR
synaptoporin
chr9_-_114937676 0.395 ENST00000374270.3
SUSD1
sushi domain containing 1
chr16_+_81478775 0.393 ENST00000537098.3
CMIP
c-Maf inducing protein
chr16_+_30075595 0.391 ENST00000563060.2
ALDOA
aldolase A, fructose-bisphosphate
chrX_+_38211777 0.385 ENST00000039007.4
OTC
ornithine carbamoyltransferase
chr3_+_63428982 0.381 ENST00000479198.1
ENST00000460711.1
ENST00000465156.1
SYNPR


synaptoporin


chr1_-_153363452 0.378 ENST00000368732.1
ENST00000368733.3
S100A8

S100 calcium binding protein A8

chr11_+_61015594 0.378 ENST00000451616.2
PGA5
pepsinogen 5, group I (pepsinogen A)
chr16_-_67693846 0.377 ENST00000602850.1
ACD
adrenocortical dysplasia homolog (mouse)
chr20_-_1373682 0.377 ENST00000381724.3
FKBP1A
FK506 binding protein 1A, 12kDa
chr3_+_138067666 0.375 ENST00000475711.1
ENST00000464896.1
MRAS

muscle RAS oncogene homolog

chr19_-_42931567 0.368 ENST00000244289.4
LIPE
lipase, hormone-sensitive
chr19_-_6767431 0.366 ENST00000437152.3
ENST00000597687.1
SH2D3A

SH2 domain containing 3A

chr22_-_19165917 0.366 ENST00000451283.1
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr1_-_27930102 0.363 ENST00000247087.5
ENST00000374011.2
AHDC1

AT hook, DNA binding motif, containing 1

chr6_+_84563295 0.363 ENST00000369687.1
RIPPLY2
ripply transcriptional repressor 2
chr19_-_6670128 0.362 ENST00000245912.3
TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr2_-_44065946 0.362 ENST00000260645.1
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr5_+_149877334 0.358 ENST00000523767.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr2_-_44065889 0.357 ENST00000543989.1
ENST00000405322.1
ABCG5

ATP-binding cassette, sub-family G (WHITE), member 5

chrX_-_45629661 0.354 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2

RP6-99M1.2

chr17_-_74722672 0.353 ENST00000397625.4
ENST00000445478.2
JMJD6

jumonji domain containing 6

chr9_+_2621798 0.353 ENST00000382100.3
VLDLR
very low density lipoprotein receptor
chrX_+_151999511 0.352 ENST00000370274.3
ENST00000440023.1
ENST00000432467.1
NSDHL


NAD(P) dependent steroid dehydrogenase-like


chr16_+_30075783 0.351 ENST00000412304.2
ALDOA
aldolase A, fructose-bisphosphate
chr4_+_140222609 0.348 ENST00000296543.5
ENST00000398947.1
NAA15

N(alpha)-acetyltransferase 15, NatA auxiliary subunit

chr7_-_32110451 0.348 ENST00000396191.1
ENST00000396182.2
PDE1C

phosphodiesterase 1C, calmodulin-dependent 70kDa

chr17_+_42925270 0.347 ENST00000253410.2
ENST00000587021.1
HIGD1B

HIG1 hypoxia inducible domain family, member 1B

chr15_-_65398647 0.345 ENST00000502113.2
UBAP1L
ubiquitin associated protein 1-like
chr5_+_174905398 0.344 ENST00000321442.5
SFXN1
sideroflexin 1
chr17_+_15604513 0.342 ENST00000481540.1
ZNF286A
Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.
chr18_-_13726510 0.341 ENST00000322247.3
ENST00000592976.1
ENST00000402563.1
ENST00000591269.1
FAM210A



family with sequence similarity 210, member A



chr3_+_148847371 0.341 ENST00000296051.2
ENST00000460120.1
HPS3

Hermansky-Pudlak syndrome 3

chr7_+_139529040 0.341 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
TBXAS1


thromboxane A synthase 1 (platelet)


chr20_-_656437 0.340 ENST00000488788.2
RP5-850E9.3
Uncharacterized protein
chr8_+_120428546 0.340 ENST00000259526.3
NOV
nephroblastoma overexpressed
chr18_+_22040620 0.339 ENST00000426880.2
HRH4
histamine receptor H4
chr4_+_2813946 0.336 ENST00000442312.2
SH3BP2
SH3-domain binding protein 2
chr3_-_48481518 0.334 ENST00000412398.2
ENST00000395696.1
CCDC51

coiled-coil domain containing 51

chr12_+_6494285 0.333 ENST00000541102.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr9_+_95709733 0.331 ENST00000375482.3
FGD3
FYVE, RhoGEF and PH domain containing 3
chr3_-_28390415 0.330 ENST00000414162.1
ENST00000420543.2
AZI2

5-azacytidine induced 2

chr6_+_30525051 0.327 ENST00000376557.3
PRR3
proline rich 3
chr9_-_130477912 0.327 ENST00000543175.1
PTRH1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr20_-_1472029 0.326 ENST00000359801.3
SIRPB2
signal-regulatory protein beta 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0042938 dipeptide transport(GO:0042938)
0.8 2.4 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.6 3.8 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.5 1.6 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.4 1.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.4 3.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.4 1.6 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.4 1.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.4 1.1 GO:2001037 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.3 1.0 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.3 1.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.3 2.1 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.2 1.4 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.2 0.5 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.2 2.0 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.2 1.3 GO:0090131 mesenchyme migration(GO:0090131)
0.2 0.6 GO:1903625 L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.2 0.6 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.2 0.6 GO:0010949 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
0.2 1.9 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 1.5 GO:0015705 iodide transport(GO:0015705)
0.2 0.5 GO:0019858 cytosine metabolic process(GO:0019858)
0.2 1.3 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.2 0.5 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 0.8 GO:0060005 vestibular reflex(GO:0060005)
0.1 1.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.8 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.4 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.1 2.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.4 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.1 1.6 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.1 0.4 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.1 0.6 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 1.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.5 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.7 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 1.7 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.8 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.3 GO:1990927 negative regulation of synaptic vesicle recycling(GO:1903422) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.5 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 1.4 GO:0022417 protein maturation by protein folding(GO:0022417)
0.1 0.5 GO:0032747 positive regulation of interleukin-23 production(GO:0032747) negative regulation of cytolysis(GO:0045918)
0.1 0.6 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.8 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.3 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.7 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.1 0.7 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.3 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.6 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.5 GO:0010193 response to ozone(GO:0010193)
0.1 0.3 GO:0001701 in utero embryonic development(GO:0001701)
0.1 0.6 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 2.2 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 1.5 GO:0090178 regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.2 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.6 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 3.6 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.6 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.4 GO:1901318 negative regulation of sperm motility(GO:1901318)
0.1 0.5 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.4 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 1.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.4 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1 0.8 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 1.1 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 0.3 GO:0016598 protein arginylation(GO:0016598)
0.1 0.3 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.2 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.1 1.2 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.1 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.5 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.1 0.2 GO:0006836 neurotransmitter transport(GO:0006836)
0.1 6.7 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1 0.6 GO:0030091 protein repair(GO:0030091)
0.1 0.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.7 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.6 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.0 0.5 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.4 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.2 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.0 0.8 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.5 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 2.1 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.4 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0 0.4 GO:0015014 protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.4 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.1 GO:0098907 protein localization to M-band(GO:0036309) regulation of SA node cell action potential(GO:0098907)
0.0 0.1 GO:0070352 positive regulation of white fat cell proliferation(GO:0070352)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.2 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367) negative regulation of cholesterol efflux(GO:0090370)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.7 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.2 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.1 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.2 GO:0021615 rhombomere development(GO:0021546) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.3 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.1 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.3 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.0 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 1.1 GO:0010165 response to X-ray(GO:0010165)
0.0 0.1 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 1.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.1 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.8 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.2 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 1.2 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.4 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 1.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.5 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 1.7 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.9 GO:0023056 positive regulation of signaling(GO:0023056)
0.0 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.3 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.1 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.3 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 1.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.2 GO:0045445 myoblast differentiation(GO:0045445)
0.0 0.5 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525) negative regulation of mitophagy(GO:1903147)
0.0 0.0 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.3 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.9 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.5 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.2 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.3 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.2 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.5 GO:0006363 transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.9 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.3 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.1 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.7 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0 1.3 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.7 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.3 GO:0006309 apoptotic DNA fragmentation(GO:0006309)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0097453 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.4 2.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.4 1.2 GO:0005588 collagen type V trimer(GO:0005588)
0.3 1.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 1.5 GO:1990425 ryanodine receptor complex(GO:1990425)
0.3 2.7 GO:0000796 condensin complex(GO:0000796)
0.2 1.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 1.1 GO:0031262 Ndc80 complex(GO:0031262)
0.2 0.9 GO:0070876 SOSS complex(GO:0070876)
0.2 0.5 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.2 0.5 GO:0042565 RNA nuclear export complex(GO:0042565)
0.1 3.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.8 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.0 GO:0097443 sorting endosome(GO:0097443)
0.1 0.8 GO:0005593 FACIT collagen trimer(GO:0005593)
0.1 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.5 GO:0071547 piP-body(GO:0071547)
0.1 2.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.8 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.3 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.2 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.1 1.5 GO:0031143 pseudopodium(GO:0031143)
0.1 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 1.6 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.2 GO:1990745 EARP complex(GO:1990745)
0.0 0.5 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0009986 cell surface(GO:0009986)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.4 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.4 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 1.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.3 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 3.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 2.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.8 GO:0005768 endosome(GO:0005768)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 1.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.4 GO:0045095 keratin filament(GO:0045095)
0.0 1.1 GO:0002102 podosome(GO:0002102)
0.0 1.7 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.0 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 2.3 GO:0001650 fibrillar center(GO:0001650)
0.0 1.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 5.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0002113 interleukin-33 binding(GO:0002113)
0.5 1.6 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.4 2.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.4 1.9 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.4 2.9 GO:0004064 arylesterase activity(GO:0004064)
0.3 1.7 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.3 0.8 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.3 1.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 0.7 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 1.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 0.6 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.2 0.6 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.2 0.8 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 0.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 0.5 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.2 2.7 GO:0048185 activin binding(GO:0048185)
0.2 0.9 GO:0051373 FATZ binding(GO:0051373)
0.1 1.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 3.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.4 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 1.5 GO:0008199 ferric iron binding(GO:0008199)
0.1 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.8 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 1.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.3 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 6.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.0 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 1.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 1.3 GO:0008565 protein transporter activity(GO:0008565)
0.1 1.5 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.3 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.4 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 1.2 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.4 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 1.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.4 GO:0004096 catalase activity(GO:0004096)
0.1 0.3 GO:0004057 arginyltransferase activity(GO:0004057)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.4 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.2 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.1 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 1.4 GO:0017166 vinculin binding(GO:0017166)
0.1 0.6 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 1.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 2.0 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 1.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.6 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.3 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 1.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.8 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.8 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 2.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 2.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.0 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 1.4 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID_ALK2_PATHWAY ALK2 signaling events
0.1 2.3 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.0 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 2.4 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 1.7 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 2.2 NABA_COLLAGENS Genes encoding collagen proteins
0.0 2.6 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 3.3 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.7 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.2 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.8 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 0.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.1 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.1 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.6 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.6 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.0 0.4 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 1.3 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.5 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.2 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.3 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.3 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.0 2.7 NABA_CORE_MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.2 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.5 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.4 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 2.3 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 2.2 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.9 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.5 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.4 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 3.3 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.7 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.8 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 2.8 REACTOME_IL_2_SIGNALING Genes involved in Interleukin-2 signaling
0.0 2.5 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.7 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.8 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.7 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.1 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 0.7 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 2.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 1.2 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 1.7 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.2 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME_OPSINS Genes involved in Opsins
0.0 0.4 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.0 REACTOME_GAB1_SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.5 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.5 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.6 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.6 REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.1 REACTOME_MRNA_CAPPING Genes involved in mRNA Capping
0.0 0.3 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.2 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex