Motif ID: UUGGCAA

Z-value: 0.508


Mature miRNA associated with seed UUGGCAA:

NamemiRBase Accession
hsa-miR-182-5p MIMAT0000259



Activity profile for motif UUGGCAA.

activity profile for motif UUGGCAA


Sorted Z-values histogram for motif UUGGCAA

Sorted Z-values for motif UUGGCAA



Network of associatons between targets according to the STRING database.



First level regulatory network of UUGGCAA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_160473996 1.401 ENST00000498165.1
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr7_-_158380465 1.294 ENST00000389413.3
ENST00000409483.1
PTPRN2

protein tyrosine phosphatase, receptor type, N polypeptide 2

chr13_+_24734844 1.279 ENST00000382108.3
SPATA13
spermatogenesis associated 13
chr6_+_135502466 1.190 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr14_+_75536280 1.092 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr6_-_10838710 0.958 ENST00000313243.2
MAK
male germ cell-associated kinase
chr5_-_16509101 0.948 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr2_-_220110187 0.944 ENST00000295759.7
ENST00000392089.2
GLB1L

galactosidase, beta 1-like

chr2_+_85981008 0.932 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr19_+_32896697 0.893 ENST00000586987.1
DPY19L3
dpy-19-like 3 (C. elegans)
chr1_+_3607228 0.857 ENST00000378285.1
ENST00000378280.1
ENST00000378288.4
TP73


tumor protein p73


chr3_+_238273 0.847 ENST00000256509.2
CHL1
cell adhesion molecule L1-like
chr5_+_50678921 0.845 ENST00000230658.7
ISL1
ISL LIM homeobox 1
chr3_+_69812877 0.827 ENST00000457080.1
ENST00000328528.6
MITF

microphthalmia-associated transcription factor

chr15_-_49255632 0.801 ENST00000332408.4
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr1_+_20512568 0.796 ENST00000375099.3
UBXN10
UBX domain protein 10
chr17_-_1532106 0.787 ENST00000301335.5
ENST00000382147.4
SLC43A2

solute carrier family 43 (amino acid system L transporter), member 2

chr12_-_56652111 0.784 ENST00000267116.7
ANKRD52
ankyrin repeat domain 52
chrX_+_16964794 0.782 ENST00000357277.3
REPS2
RALBP1 associated Eps domain containing 2
chr10_-_46167722 0.747 ENST00000374366.3
ENST00000344646.5
ZFAND4

zinc finger, AN1-type domain 4

chr10_-_62704005 0.738 ENST00000337910.5
RHOBTB1
Rho-related BTB domain containing 1
chr2_+_97481974 0.711 ENST00000377060.3
ENST00000305510.3
CNNM3

cyclin M3

chr7_+_30174426 0.691 ENST00000324453.8
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr1_-_217262969 0.681 ENST00000361525.3
ESRRG
estrogen-related receptor gamma
chr2_-_213403565 0.657 ENST00000342788.4
ENST00000436443.1
ERBB4

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

chr19_-_14316980 0.652 ENST00000361434.3
ENST00000340736.6
LPHN1

latrophilin 1

chr6_-_90121938 0.640 ENST00000369415.4
RRAGD
Ras-related GTP binding D
chr11_+_46299199 0.631 ENST00000529193.1
ENST00000288400.3
CREB3L1

cAMP responsive element binding protein 3-like 1

chr3_-_9994021 0.607 ENST00000411976.2
ENST00000412055.1
PRRT3

proline-rich transmembrane protein 3

chr1_+_57110972 0.605 ENST00000371244.4
PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr17_+_72322346 0.604 ENST00000551294.1
ENST00000389916.4
KIF19

kinesin family member 19

chr20_-_21494654 0.603 ENST00000377142.4
NKX2-2
NK2 homeobox 2
chr6_+_138483058 0.596 ENST00000251691.4
KIAA1244
KIAA1244
chr3_+_179370517 0.595 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr8_+_101170257 0.573 ENST00000251809.3
SPAG1
sperm associated antigen 1
chr14_-_90085458 0.569 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3


forkhead box N3


chr3_-_114790179 0.560 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr6_-_79787902 0.547 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr4_-_83483395 0.546 ENST00000515780.2
TMEM150C
transmembrane protein 150C
chr2_-_152955537 0.535 ENST00000201943.5
ENST00000539935.1
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr11_+_111807863 0.532 ENST00000440460.2
DIXDC1
DIX domain containing 1
chr18_-_54305658 0.518 ENST00000586262.1
ENST00000217515.6
TXNL1

thioredoxin-like 1

chr10_+_72164135 0.517 ENST00000373218.4
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr8_+_28351707 0.509 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
FZD3


frizzled family receptor 3


chr1_+_180601139 0.494 ENST00000367590.4
ENST00000367589.3
XPR1

xenotropic and polytropic retrovirus receptor 1

chr6_+_36164487 0.487 ENST00000357641.6
BRPF3
bromodomain and PHD finger containing, 3
chr6_+_1312675 0.486 ENST00000296839.2
FOXQ1
forkhead box Q1
chr6_-_99395787 0.480 ENST00000369244.2
ENST00000229971.1
FBXL4

F-box and leucine-rich repeat protein 4

chr1_+_109656579 0.476 ENST00000526264.1
ENST00000369939.3
KIAA1324

KIAA1324

chr3_+_61547585 0.469 ENST00000295874.10
ENST00000474889.1
PTPRG

protein tyrosine phosphatase, receptor type, G

chr5_-_179499086 0.464 ENST00000261947.4
RNF130
ring finger protein 130
chr12_-_94853716 0.463 ENST00000339839.5
ENST00000397809.5
ENST00000547575.1
CCDC41


coiled-coil domain containing 41


chr3_+_14444063 0.462 ENST00000454876.2
ENST00000360861.3
ENST00000416216.2
SLC6A6


solute carrier family 6 (neurotransmitter transporter), member 6


chr6_-_36842784 0.459 ENST00000373699.5
PPIL1
peptidylprolyl isomerase (cyclophilin)-like 1
chr3_+_181429704 0.453 ENST00000431565.2
ENST00000325404.1
SOX2

SRY (sex determining region Y)-box 2

chr21_-_34852304 0.447 ENST00000542230.2
TMEM50B
transmembrane protein 50B
chr1_-_86043921 0.433 ENST00000535924.2
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr8_+_120885949 0.433 ENST00000523492.1
ENST00000286234.5
DEPTOR

DEP domain containing MTOR-interacting protein

chr4_+_108745711 0.433 ENST00000394684.4
SGMS2
sphingomyelin synthase 2
chr14_+_74111578 0.429 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1






dynein, axonemal, light chain 1






chr5_+_153825510 0.423 ENST00000297109.6
SAP30L
SAP30-like
chr2_-_86564776 0.422 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1


receptor accessory protein 1


chr16_+_77822427 0.421 ENST00000302536.2
VAT1L
vesicle amine transport 1-like
chr14_-_53619816 0.420 ENST00000323669.5
ENST00000395606.1
ENST00000357758.3
DDHD1


DDHD domain containing 1


chr13_+_100634004 0.420 ENST00000376335.3
ZIC2
Zic family member 2
chr9_-_139922631 0.420 ENST00000341511.6
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr19_-_33555780 0.415 ENST00000254260.3
ENST00000400226.4
RHPN2

rhophilin, Rho GTPase binding protein 2

chr6_-_80247105 0.410 ENST00000369846.4
LCA5
Leber congenital amaurosis 5
chrX_+_9431324 0.409 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X





transducin (beta)-like 1X-linked





chr3_+_187930719 0.407 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr5_-_133968529 0.407 ENST00000402673.2
SAR1B
SAR1 homolog B (S. cerevisiae)
chr6_+_80341000 0.405 ENST00000369838.4
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr16_+_50775948 0.404 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD


cylindromatosis (turban tumor syndrome)


chr7_+_17338239 0.401 ENST00000242057.4
AHR
aryl hydrocarbon receptor
chr9_-_80646374 0.393 ENST00000286548.4
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr7_+_94139105 0.391 ENST00000297273.4
CASD1
CAS1 domain containing 1
chrX_+_72783026 0.389 ENST00000373504.6
ENST00000373502.5
CHIC1

cysteine-rich hydrophobic domain 1

chr14_-_39901618 0.389 ENST00000554932.1
ENST00000298097.7
FBXO33

F-box protein 33

chr21_-_40685477 0.388 ENST00000342449.3
BRWD1
bromodomain and WD repeat domain containing 1
chr2_+_45878790 0.386 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr1_-_234614849 0.380 ENST00000040877.1
TARBP1
TAR (HIV-1) RNA binding protein 1
chr7_+_107110488 0.379 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr3_-_161090660 0.375 ENST00000359175.4
SPTSSB
serine palmitoyltransferase, small subunit B
chr10_+_104613980 0.373 ENST00000339834.5
C10orf32
chromosome 10 open reading frame 32
chr12_+_110906169 0.373 ENST00000377673.5
FAM216A
family with sequence similarity 216, member A
chr4_+_184826418 0.371 ENST00000308497.4
ENST00000438269.1
STOX2

storkhead box 2

chr14_+_57735614 0.371 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr2_+_46524537 0.369 ENST00000263734.3
EPAS1
endothelial PAS domain protein 1
chr20_+_42086525 0.367 ENST00000244020.3
SRSF6
serine/arginine-rich splicing factor 6
chr8_+_123793633 0.367 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr17_+_4981535 0.360 ENST00000318833.3
ZFP3
ZFP3 zinc finger protein
chr10_-_98480243 0.355 ENST00000339364.5
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr8_-_130951940 0.354 ENST00000522250.1
ENST00000522941.1
ENST00000522746.1
ENST00000520204.1
ENST00000519070.1
ENST00000520254.1
ENST00000519824.2
ENST00000519540.1
FAM49B







family with sequence similarity 49, member B







chr3_-_46037299 0.351 ENST00000296137.2
FYCO1
FYVE and coiled-coil domain containing 1
chr9_+_71320596 0.348 ENST00000265382.3
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr9_+_976964 0.342 ENST00000190165.2
DMRT3
doublesex and mab-3 related transcription factor 3
chr13_+_98794810 0.335 ENST00000595437.1
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr15_-_83316254 0.328 ENST00000567678.1
ENST00000450751.2
CPEB1

cytoplasmic polyadenylation element binding protein 1

chrX_+_70752917 0.327 ENST00000373719.3
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr7_+_94285637 0.323 ENST00000482108.1
ENST00000488574.1
PEG10

paternally expressed 10

chr17_-_27621125 0.323 ENST00000579665.1
ENST00000225388.4
NUFIP2

nuclear fragile X mental retardation protein interacting protein 2

chr22_-_44894178 0.319 ENST00000341255.3
LDOC1L
leucine zipper, down-regulated in cancer 1-like
chrX_+_17393543 0.319 ENST00000380060.3
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr7_-_130080977 0.318 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr14_+_56046914 0.316 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
KTN1



kinectin 1 (kinesin receptor)



chr20_-_50419055 0.307 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr1_+_101361626 0.302 ENST00000370112.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr10_-_13390270 0.300 ENST00000378614.4
ENST00000545675.1
ENST00000327347.5
SEPHS1


selenophosphate synthetase 1


chrX_-_117250740 0.296 ENST00000371882.1
ENST00000540167.1
ENST00000545703.1
KLHL13


kelch-like family member 13


chr10_-_116286656 0.296 ENST00000428430.1
ENST00000369266.3
ENST00000392952.3
ABLIM1


actin binding LIM protein 1


chr1_+_113615794 0.293 ENST00000361127.5
LRIG2
leucine-rich repeats and immunoglobulin-like domains 2
chr20_-_50384864 0.292 ENST00000311637.5
ENST00000402822.1
ATP9A

ATPase, class II, type 9A

chr4_-_88141755 0.290 ENST00000273963.5
KLHL8
kelch-like family member 8
chr4_+_41362796 0.288 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1




LIM and calponin homology domains 1




chr7_-_95225768 0.288 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr5_-_9546180 0.285 ENST00000382496.5
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr16_-_87525651 0.282 ENST00000268616.4
ZCCHC14
zinc finger, CCHC domain containing 14
chr10_-_62149433 0.281 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr3_+_155588300 0.275 ENST00000496455.2
GMPS
guanine monphosphate synthase
chr20_+_33292068 0.273 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2


tumor protein p53 inducible nuclear protein 2


chr11_-_64612041 0.272 ENST00000342711.5
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr6_+_69345166 0.272 ENST00000370598.1
BAI3
brain-specific angiogenesis inhibitor 3
chr7_+_87257701 0.271 ENST00000338056.3
ENST00000493037.1
RUNDC3B

RUN domain containing 3B

chr11_-_115375107 0.271 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr7_-_112727774 0.269 ENST00000297146.3
ENST00000501255.2
GPR85

G protein-coupled receptor 85

chr9_+_104161123 0.269 ENST00000374861.3
ENST00000339664.2
ENST00000259395.4
ZNF189


zinc finger protein 189


chr12_-_104234966 0.265 ENST00000392876.3
NT5DC3
5'-nucleotidase domain containing 3
chr1_+_9294822 0.259 ENST00000377403.2
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr1_+_15943995 0.257 ENST00000480945.1
DDI2
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr6_+_71998506 0.257 ENST00000370435.4
OGFRL1
opioid growth factor receptor-like 1
chr1_-_16678914 0.256 ENST00000375592.3
FBXO42
F-box protein 42
chr22_-_39548627 0.253 ENST00000216133.5
CBX7
chromobox homolog 7
chr6_+_17600576 0.251 ENST00000259963.3
FAM8A1
family with sequence similarity 8, member A1
chr2_+_162272605 0.250 ENST00000389554.3
TBR1
T-box, brain, 1
chr1_+_231664390 0.246 ENST00000366639.4
ENST00000413309.2
TSNAX

translin-associated factor X

chr17_+_61699766 0.245 ENST00000579585.1
ENST00000584573.1
ENST00000361733.3
ENST00000361357.3
MAP3K3



mitogen-activated protein kinase kinase kinase 3



chr6_+_56954867 0.244 ENST00000370708.4
ENST00000370702.1
ZNF451

zinc finger protein 451

chr8_+_61429416 0.240 ENST00000262646.7
ENST00000531289.1
RAB2A

RAB2A, member RAS oncogene family

chr4_-_16228120 0.236 ENST00000405303.2
TAPT1
transmembrane anterior posterior transformation 1
chr14_+_105331596 0.234 ENST00000556508.1
ENST00000414716.3
ENST00000453495.1
ENST00000418279.1
CEP170B



centrosomal protein 170B



chr3_-_133614597 0.233 ENST00000285208.4
ENST00000460865.3
RAB6B

RAB6B, member RAS oncogene family

chr13_+_108870714 0.232 ENST00000375898.3
ABHD13
abhydrolase domain containing 13
chr8_-_103876965 0.232 ENST00000337198.5
AZIN1
antizyme inhibitor 1
chr13_+_115079949 0.231 ENST00000361283.1
CHAMP1
chromosome alignment maintaining phosphoprotein 1
chr9_+_79074068 0.230 ENST00000444201.2
ENST00000376730.4
GCNT1

glucosaminyl (N-acetyl) transferase 1, core 2

chr5_+_71403061 0.229 ENST00000512974.1
ENST00000296755.7
MAP1B

microtubule-associated protein 1B

chr17_-_33760164 0.228 ENST00000445092.1
ENST00000394562.1
ENST00000447040.2
SLFN12


schlafen family member 12


chr4_+_146402925 0.224 ENST00000302085.4
SMAD1
SMAD family member 1
chr11_-_79151695 0.223 ENST00000278550.7
TENM4
teneurin transmembrane protein 4
chr7_-_25164969 0.222 ENST00000305786.2
CYCS
cytochrome c, somatic
chr12_-_56727487 0.220 ENST00000548043.1
ENST00000425394.2
PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr1_-_202858227 0.219 ENST00000367262.3
RABIF
RAB interacting factor
chr1_-_231004220 0.217 ENST00000366663.5
C1orf198
chromosome 1 open reading frame 198
chr1_-_154934200 0.215 ENST00000368457.2
PYGO2
pygopus family PHD finger 2
chr10_+_102295616 0.214 ENST00000299163.6
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr10_-_61469837 0.212 ENST00000395348.3
SLC16A9
solute carrier family 16, member 9
chr12_-_42538657 0.207 ENST00000398675.3
GXYLT1
glucoside xylosyltransferase 1
chr5_-_90679145 0.207 ENST00000265138.3
ARRDC3
arrestin domain containing 3
chr3_-_134093395 0.204 ENST00000249883.5
AMOTL2
angiomotin like 2
chr22_-_36903101 0.203 ENST00000397224.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr12_+_104682496 0.202 ENST00000378070.4
TXNRD1
thioredoxin reductase 1
chr9_-_79520989 0.201 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
PRUNE2


prune homolog 2 (Drosophila)


chr11_-_46142948 0.198 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr2_+_46769798 0.198 ENST00000238738.4
RHOQ
ras homolog family member Q
chr1_-_15911510 0.196 ENST00000375826.3
AGMAT
agmatine ureohydrolase (agmatinase)
chr10_+_111767720 0.196 ENST00000356080.4
ENST00000277900.8
ADD3

adducin 3 (gamma)

chr19_-_33793430 0.194 ENST00000498907.2
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr1_-_177133818 0.192 ENST00000424564.2
ENST00000361833.2
ASTN1

astrotactin 1

chr9_-_125675576 0.190 ENST00000373659.3
ZBTB6
zinc finger and BTB domain containing 6
chr20_+_30865429 0.190 ENST00000375712.3
KIF3B
kinesin family member 3B
chr5_-_114880533 0.190 ENST00000274457.3
FEM1C
fem-1 homolog c (C. elegans)
chr12_+_113229737 0.187 ENST00000551052.1
ENST00000415485.3
RPH3A

rabphilin 3A homolog (mouse)

chr9_+_91003271 0.186 ENST00000375859.3
ENST00000541629.1
SPIN1

spindlin 1

chr12_+_69864129 0.186 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
FRS2









fibroblast growth factor receptor substrate 2









chr9_-_27573392 0.185 ENST00000380003.3
C9orf72
chromosome 9 open reading frame 72
chr11_+_123396528 0.185 ENST00000322282.7
ENST00000529750.1
GRAMD1B

GRAM domain containing 1B

chr7_+_114055052 0.184 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2







forkhead box P2







chr6_-_6007200 0.183 ENST00000244766.2
NRN1
neuritin 1
chr2_-_68479614 0.183 ENST00000234310.3
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr1_+_65210772 0.182 ENST00000371072.4
ENST00000294428.3
RAVER2

ribonucleoprotein, PTB-binding 2

chr14_+_71374122 0.182 ENST00000304743.2
ENST00000238570.5
PCNX

pecanex homolog (Drosophila)

chr2_+_208394616 0.181 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1


cAMP responsive element binding protein 1


chrX_+_101967257 0.181 ENST00000543253.1
ENST00000535209.1
GPRASP2

G protein-coupled receptor associated sorting protein 2

chr20_+_277737 0.178 ENST00000382352.3
ZCCHC3
zinc finger, CCHC domain containing 3
chr10_-_52383644 0.177 ENST00000361781.2
SGMS1
sphingomyelin synthase 1
chr2_+_86947296 0.177 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr2_+_220408724 0.174 ENST00000421791.1
ENST00000373883.3
ENST00000451952.1
TMEM198


transmembrane protein 198


chr3_+_150804676 0.174 ENST00000474524.1
ENST00000273432.4
MED12L

mediator complex subunit 12-like

chr5_-_37839782 0.172 ENST00000326524.2
ENST00000515058.1
GDNF

glial cell derived neurotrophic factor

chr3_-_88108192 0.171 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr2_-_40679186 0.170 ENST00000406785.2
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr6_-_91006461 0.169 ENST00000257749.4
ENST00000343122.3
ENST00000406998.2
ENST00000453877.1
BACH2



BTB and CNC homology 1, basic leucine zipper transcription factor 2



chr12_-_110434021 0.167 ENST00000355312.3
ENST00000551209.1
ENST00000550186.1
GIT2


G protein-coupled receptor kinase interacting ArfGAP 2


chr5_+_112312416 0.167 ENST00000389063.2
DCP2
decapping mRNA 2
chr7_+_142985308 0.166 ENST00000310447.5
CASP2
caspase 2, apoptosis-related cysteine peptidase
chrX_-_34675391 0.166 ENST00000275954.3
TMEM47
transmembrane protein 47
chr7_-_47621736 0.166 ENST00000311160.9
TNS3
tensin 3
chr9_+_129677039 0.166 ENST00000259351.5
ENST00000424082.2
ENST00000394022.3
ENST00000394011.3
ENST00000319107.4
RALGPS1




Ral GEF with PH domain and SH3 binding motif 1




chr7_+_66093851 0.165 ENST00000275532.3
KCTD7
potassium channel tetramerization domain containing 7
chr6_-_109703663 0.165 ENST00000368961.5
CD164
CD164 molecule, sialomucin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.3 0.8 GO:0021524 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913)
0.2 0.7 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.2 0.6 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 0.6 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.2 0.5 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.1 0.4 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.4 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 0.9 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 1.0 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.1 0.3 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.4 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.6 GO:0071233 cellular response to leucine(GO:0071233)
0.1 0.2 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.6 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.4 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.2 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.5 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.5 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 0.4 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.4 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.1 0.6 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.4 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.1 GO:0060066 oviduct development(GO:0060066)
0.1 0.4 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.5 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.6 GO:0072501 cellular divalent inorganic anion homeostasis(GO:0072501)
0.1 0.3 GO:0021764 amygdala development(GO:0021764)
0.1 0.1 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.0 0.5 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0061010 gall bladder development(GO:0061010)
0.0 0.1 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.0 0.2 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.4 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.3 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.1 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.9 GO:0060044 negative regulation of JUN kinase activity(GO:0043508) negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0072720 response to dithiothreitol(GO:0072720)
0.0 0.8 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.1 GO:0015993 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.6 GO:0035404 histone-serine phosphorylation(GO:0035404) fatty acid homeostasis(GO:0055089)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.3 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.4 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.2 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.0 1.0 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.2 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
0.0 0.8 GO:0035640 exploration behavior(GO:0035640)
0.0 0.3 GO:0060352 cell adhesion molecule production(GO:0060352)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.1 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.5 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.8 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154) positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.0 GO:1902741 positive regulation of interferon-alpha production(GO:0032727) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.4 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.0 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.0 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.0 0.0 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.0 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.2 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.0 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.3 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 1.5 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 0.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.0 GO:0018076 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.2 GO:0000050 urea cycle(GO:0000050)
0.0 0.8 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 1.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.1 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.0 0.2 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.6 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0060672 lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463) epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.3 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.0 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.2 GO:0038111 interleukin-7-mediated signaling pathway(GO:0038111) response to interleukin-7(GO:0098760) cellular response to interleukin-7(GO:0098761)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353) embryonic process involved in female pregnancy(GO:0060136)
0.0 0.0 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.0 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.0 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.3 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.6 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.0 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:1905049 negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.0 0.2 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.3 GO:0043235 receptor complex(GO:0043235)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 0.2 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.2 GO:0034657 GID complex(GO:0034657)
0.1 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.4 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 1.4 GO:0097542 ciliary tip(GO:0097542)
0.0 0.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.0 GO:0043291 RAVE complex(GO:0043291)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 1.3 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.0 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009) cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.2 0.6 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.4 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.1 0.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.6 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.3 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 0.4 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.4 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 0.3 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 1.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.7 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.9 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.3 GO:0017057 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.3 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.4 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.3 GO:0097363 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.2 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 0.2 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.1 0.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.2 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.9 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.4 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 1.8 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.4 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.1 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.5 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.7 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.2 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.9 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 1.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.8 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.9 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.3 GO:0005168 neurotrophin TRK receptor binding(GO:0005167) neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.0 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.0 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.0 0.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 1.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 0.3 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.5 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 1.1 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 1.0 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 1.0 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.2 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.7 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 0.4 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.6 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.7 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.2 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.0 0.4 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway