Motif ID: ZNF350

Z-value: 0.526


Transcription factors associated with ZNF350:

Gene SymbolEntrez IDGene Name
ZNF350 ENSG00000256683.2 ZNF350

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZNF350hg19_v2_chr19_-_52489923_524901130.433.7e-02Click!


Activity profile for motif ZNF350.

activity profile for motif ZNF350


Sorted Z-values histogram for motif ZNF350

Sorted Z-values for motif ZNF350



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF350

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_132286754 2.348 ENST00000434330.1
CCDC74A
coiled-coil domain containing 74A
chr2_+_132287237 1.949 ENST00000467992.2
CCDC74A
coiled-coil domain containing 74A
chr4_+_75858290 1.681 ENST00000513238.1
PARM1
prostate androgen-regulated mucin-like protein 1
chr1_-_46089718 1.525 ENST00000421127.2
ENST00000343901.2
ENST00000528266.1
CCDC17


coiled-coil domain containing 17


chr17_+_68071389 1.524 ENST00000283936.1
ENST00000392671.1
KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr4_+_75858318 1.517 ENST00000307428.7
PARM1
prostate androgen-regulated mucin-like protein 1
chr17_+_68071458 1.509 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr3_+_100328433 1.422 ENST00000273352.3
GPR128
G protein-coupled receptor 128
chr1_-_46089639 1.147 ENST00000445048.2
CCDC17
coiled-coil domain containing 17
chr16_+_69600209 1.103 ENST00000566899.1
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr1_-_98510843 1.043 ENST00000413670.2
ENST00000538428.1
MIR137HG

MIR137 host gene (non-protein coding)

chr5_+_42423872 0.987 ENST00000230882.4
ENST00000357703.3
GHR

growth hormone receptor

chr17_+_68165657 0.977 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr11_-_63381925 0.969 ENST00000415826.1
PLA2G16
phospholipase A2, group XVI
chr16_+_69600058 0.849 ENST00000393742.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr20_+_62367989 0.846 ENST00000309546.3
LIME1
Lck interacting transmembrane adaptor 1
chr2_+_233497931 0.813 ENST00000264059.3
EFHD1
EF-hand domain family, member D1
chr11_-_45687128 0.570 ENST00000308064.2
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr2_-_157198860 0.559 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr12_+_50451331 0.524 ENST00000228468.4
ASIC1
acid-sensing (proton-gated) ion channel 1
chr2_+_120301997 0.522 ENST00000602047.1
PCDP1
Primary ciliary dyskinesia protein 1
chr2_+_120302041 0.518 ENST00000442513.3
ENST00000413369.3
PCDP1

Primary ciliary dyskinesia protein 1

chr12_+_50451462 0.510 ENST00000447966.2
ASIC1
acid-sensing (proton-gated) ion channel 1
chr14_+_96671016 0.490 ENST00000542454.2
ENST00000554311.1
ENST00000306005.3
ENST00000539359.1
ENST00000553811.1
BDKRB2



RP11-404P21.8
bradykinin receptor B2



Uncharacterized protein
chr18_+_77155856 0.487 ENST00000253506.5
ENST00000591814.1
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr4_-_76008706 0.458 ENST00000562355.1
ENST00000563602.1
RP11-44F21.5

RP11-44F21.5

chr12_+_81471816 0.455 ENST00000261206.3
ACSS3
acyl-CoA synthetase short-chain family member 3
chr13_-_96329048 0.452 ENST00000606011.1
ENST00000499499.2
DNAJC3-AS1

DNAJC3 antisense RNA 1 (head to head)

chr3_-_113775328 0.436 ENST00000483766.1
ENST00000545063.1
ENST00000491000.1
ENST00000295878.3
KIAA1407



KIAA1407



chr11_-_62473776 0.414 ENST00000278893.7
ENST00000407022.3
ENST00000421906.1
BSCL2


Berardinelli-Seip congenital lipodystrophy 2 (seipin)


chr11_-_63381823 0.404 ENST00000323646.5
PLA2G16
phospholipase A2, group XVI
chr17_+_7487146 0.401 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
MPDU1





mannose-P-dolichol utilization defect 1





chr1_-_33647267 0.386 ENST00000291416.5
TRIM62
tripartite motif containing 62
chr11_-_8954491 0.386 ENST00000526227.1
ENST00000525780.1
ENST00000326053.5
C11orf16


chromosome 11 open reading frame 16


chr11_-_62473706 0.363 ENST00000403550.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr4_+_6784401 0.353 ENST00000425103.1
ENST00000307659.5
KIAA0232

KIAA0232

chr8_+_86157699 0.352 ENST00000321764.3
CA13
carbonic anhydrase XIII
chr11_-_327537 0.323 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr11_-_414948 0.316 ENST00000530494.1
ENST00000528209.1
ENST00000431843.2
ENST00000528058.1
SIGIRR



single immunoglobulin and toll-interleukin 1 receptor (TIR) domain



chr3_-_11623804 0.281 ENST00000451674.2
VGLL4
vestigial like 4 (Drosophila)
chr17_+_6554971 0.266 ENST00000391428.2
C17orf100
chromosome 17 open reading frame 100
chr3_+_140947563 0.265 ENST00000505013.1
ACPL2
acid phosphatase-like 2
chr10_-_12084770 0.249 ENST00000357604.5
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr16_+_71879861 0.247 ENST00000568581.1
ENST00000427980.2
IST1
ATXN1L
increased sodium tolerance 1 homolog (yeast)
ataxin 1-like
chr6_-_56707943 0.247 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
DST




dystonin




chr11_-_119217365 0.241 ENST00000445041.2
ENST00000360167.4
ENST00000555262.1
ENST00000449574.2
C1QTNF5
MFRP


C1q and tumor necrosis factor related protein 5
membrane frizzled-related protein


chr10_+_69644404 0.233 ENST00000212015.6
SIRT1
sirtuin 1
chr11_-_7041466 0.227 ENST00000536068.1
ENST00000278314.4
ZNF214

zinc finger protein 214

chr18_+_77155942 0.224 ENST00000397790.2
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr16_+_14802801 0.222 ENST00000526520.1
ENST00000531598.2
NPIPA3

nuclear pore complex interacting protein family, member A3

chr11_+_64323428 0.209 ENST00000377581.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr7_+_2559399 0.205 ENST00000222725.5
ENST00000359574.3
LFNG

LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr8_+_144295067 0.202 ENST00000330824.2
GPIHBP1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr11_-_9113093 0.202 ENST00000450649.2
SCUBE2
signal peptide, CUB domain, EGF-like 2
chr16_+_67282853 0.170 ENST00000299798.11
SLC9A5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr15_+_57210818 0.167 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
TCF12




transcription factor 12




chr1_+_22970119 0.161 ENST00000374640.4
ENST00000374639.3
ENST00000374637.1
C1QC


complement component 1, q subcomponent, C chain


chr12_+_131438443 0.157 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr5_-_107717058 0.156 ENST00000359660.5
FBXL17
F-box and leucine-rich repeat protein 17
chr11_-_9113137 0.151 ENST00000520467.1
ENST00000309263.3
ENST00000457346.2
SCUBE2


signal peptide, CUB domain, EGF-like 2


chr4_+_108910870 0.143 ENST00000403312.1
ENST00000603302.1
ENST00000309522.3
HADH


hydroxyacyl-CoA dehydrogenase


chr16_+_31225337 0.140 ENST00000322122.3
TRIM72
tripartite motif containing 72
chr6_-_28303901 0.136 ENST00000439158.1
ENST00000446474.1
ENST00000414431.1
ENST00000344279.6
ENST00000453745.1
ZSCAN31




zinc finger and SCAN domain containing 31




chr19_+_42829702 0.131 ENST00000334370.4
MEGF8
multiple EGF-like-domains 8
chr10_-_94003003 0.131 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr4_+_108911036 0.125 ENST00000505878.1
HADH
hydroxyacyl-CoA dehydrogenase
chr1_-_51425902 0.123 ENST00000396153.2
FAF1
Fas (TNFRSF6) associated factor 1
chr8_-_12612962 0.121 ENST00000398246.3
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr1_+_228395755 0.120 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
OBSCN




obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF




chr2_+_177025619 0.117 ENST00000410016.1
HOXD3
homeobox D3
chrX_-_17878827 0.117 ENST00000360011.1
RAI2
retinoic acid induced 2
chr11_-_64612041 0.115 ENST00000342711.5
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr14_+_73603126 0.115 ENST00000557356.1
ENST00000556864.1
ENST00000556533.1
ENST00000556951.1
ENST00000557293.1
ENST00000553719.1
ENST00000553599.1
ENST00000556011.1
ENST00000394157.3
ENST00000357710.4
ENST00000324501.5
ENST00000560005.2
ENST00000555254.1
ENST00000261970.3
ENST00000344094.3
ENST00000554131.1
ENST00000557037.1
PSEN1
















presenilin 1
















chr1_+_202792385 0.099 ENST00000549576.1
RP11-480I12.4
Putative inactive alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein LOC641515
chr1_-_247094628 0.091 ENST00000366508.1
ENST00000326225.3
ENST00000391829.2
AHCTF1


AT hook containing transcription factor 1


chr13_+_96329381 0.090 ENST00000602402.1
ENST00000376795.6
DNAJC3

DnaJ (Hsp40) homolog, subfamily C, member 3

chr1_+_204797749 0.089 ENST00000367172.4
ENST00000367171.4
ENST00000367170.4
ENST00000338515.6
ENST00000339876.6
ENST00000338586.6
ENST00000539706.1
ENST00000360049.4
ENST00000367169.4
ENST00000446412.1
ENST00000403080.1
NFASC










neurofascin










chr21_-_30365136 0.083 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
LTN1


listerin E3 ubiquitin protein ligase 1


chr17_+_19030782 0.081 ENST00000344415.4
ENST00000577213.1
GRAPL

GRB2-related adaptor protein-like

chr11_-_64511789 0.078 ENST00000419843.1
ENST00000394430.1
RASGRP2

RAS guanyl releasing protein 2 (calcium and DAG-regulated)

chr15_+_57210961 0.077 ENST00000557843.1
TCF12
transcription factor 12
chr10_+_7860460 0.075 ENST00000344293.5
TAF3
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
chr12_-_53228079 0.070 ENST00000330553.5
KRT79
keratin 79
chr19_+_57050317 0.066 ENST00000301318.3
ENST00000591844.1
ZFP28

ZFP28 zinc finger protein

chr12_+_54519842 0.065 ENST00000508564.1
RP11-834C11.4
RP11-834C11.4
chr15_-_43029252 0.065 ENST00000563260.1
ENST00000356231.3
CDAN1

codanin 1

chr1_-_200379104 0.063 ENST00000367352.3
ZNF281
zinc finger protein 281
chr10_-_120938303 0.063 ENST00000356951.3
ENST00000298510.2
PRDX3

peroxiredoxin 3

chr3_-_155524049 0.063 ENST00000534941.1
ENST00000340171.2
C3orf33

chromosome 3 open reading frame 33

chr13_-_37633567 0.052 ENST00000464744.1
SUPT20H
suppressor of Ty 20 homolog (S. cerevisiae)
chr1_+_173446405 0.047 ENST00000340385.5
PRDX6
peroxiredoxin 6
chr10_+_50822083 0.037 ENST00000337653.2
ENST00000395562.2
CHAT

choline O-acetyltransferase

chr17_-_18950310 0.037 ENST00000573099.1
GRAP
GRB2-related adaptor protein
chr1_+_156611960 0.037 ENST00000361588.5
BCAN
brevican
chr3_-_128902729 0.034 ENST00000451728.2
ENST00000446936.2
ENST00000502976.1
ENST00000500450.2
ENST00000441626.2
CNBP




CCHC-type zinc finger, nucleic acid binding protein




chr1_+_156611704 0.027 ENST00000329117.5
BCAN
brevican
chr8_-_144679296 0.025 ENST00000317198.6
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr2_+_219524473 0.022 ENST00000439945.1
ENST00000431802.1
BCS1L

BC1 (ubiquinol-cytochrome c reductase) synthesis-like

chr13_-_44980021 0.019 ENST00000432701.2
ENST00000607312.1
LINC01071

long intergenic non-protein coding RNA 1071

chr1_-_200379129 0.018 ENST00000367353.1
ZNF281
zinc finger protein 281
chr3_-_151176497 0.017 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr19_+_5681011 0.011 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L









hydroxysteroid (11-beta) dehydrogenase 1-like









chr2_+_235860616 0.011 ENST00000392011.2
SH3BP4
SH3-domain binding protein 4
chr2_+_120517174 0.010 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr22_-_50964558 0.006 ENST00000535425.1
ENST00000439934.1
SCO2

SCO2 cytochrome c oxidase assembly protein

chr1_-_200379180 0.002 ENST00000294740.3
ZNF281
zinc finger protein 281
chr9_-_99616642 0.001 ENST00000478850.1
ENST00000481138.1
ZNF782

zinc finger protein 782

chr2_+_219524379 0.001 ENST00000443791.1
ENST00000359273.3
ENST00000392109.1
ENST00000392110.2
ENST00000423377.1
ENST00000392111.2
ENST00000412366.1
BCS1L






BC1 (ubiquinol-cytochrome c reductase) synthesis-like







Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.2 1.0 GO:0000255 allantoin metabolic process(GO:0000255)
0.2 0.6 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 1.0 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 1.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 3.0 GO:0010107 potassium ion import(GO:0010107)
0.1 3.2 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.3 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.8 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 2.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.2 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.5 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.6 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:1904796 regulation of core promoter binding(GO:1904796)
0.0 0.7 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.1 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.2 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0070195 growth hormone receptor complex(GO:0070195)
0.2 0.8 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 4.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 1.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 3.5 GO:0005770 late endosome(GO:0005770)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 4.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 1.0 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.2 0.5 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.2 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.7 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.2 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.0 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 3.5 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 1.0 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.3 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi