Motif ID: Ar

Z-value: 1.257


Transcription factors associated with Ar:

Gene SymbolEntrez IDGene Name
Ar ENSMUSG00000046532.7 Ar

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Armm10_v2_chrX_+_98149666_98149721-0.401.5e-02Click!


Activity profile for motif Ar.

activity profile for motif Ar


Sorted Z-values histogram for motif Ar

Sorted Z-values for motif Ar



Network of associatons between targets according to the STRING database.



First level regulatory network of Ar

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_28563362 13.988 ENSMUST00000028161.5
Cel
carboxyl ester lipase
chr9_+_110419750 6.634 ENSMUST00000035061.6
Ngp
neutrophilic granule protein
chr10_+_75566257 6.611 ENSMUST00000129232.1
ENSMUST00000143792.1
Ggt1

gamma-glutamyltransferase 1

chr5_-_134915512 5.756 ENSMUST00000008987.4
Cldn13
claudin 13
chr8_-_107065632 4.989 ENSMUST00000034393.5
Tmed6
transmembrane emp24 protein transport domain containing 6
chr8_+_94179089 4.804 ENSMUST00000034215.6
Mt1
metallothionein 1
chr6_-_116461024 4.156 ENSMUST00000164547.1
ENSMUST00000170186.1
Alox5

arachidonate 5-lipoxygenase

chr17_+_29114142 4.145 ENSMUST00000141797.1
ENSMUST00000132262.1
ENSMUST00000141239.1
ENSMUST00000138816.1
Gm16194



predicted gene 16194



chr14_+_51853699 3.998 ENSMUST00000169070.1
ENSMUST00000074477.6
Ear6

eosinophil-associated, ribonuclease A family, member 6

chr4_-_137409777 3.692 ENSMUST00000024200.6
Gm13011
predicted gene 13011
chr6_-_116461151 3.618 ENSMUST00000026795.6
Alox5
arachidonate 5-lipoxygenase
chr11_-_116076986 3.603 ENSMUST00000153408.1
Unc13d
unc-13 homolog D (C. elegans)
chr5_-_145720124 3.531 ENSMUST00000094111.4
Cyp3a41a
cytochrome P450, family 3, subfamily a, polypeptide 41A
chr2_-_32387760 3.446 ENSMUST00000050785.8
Lcn2
lipocalin 2
chr17_-_31144271 3.406 ENSMUST00000024826.7
Tff2
trefoil factor 2 (spasmolytic protein 1)
chr5_-_145584723 3.391 ENSMUST00000075837.6
Cyp3a41b
cytochrome P450, family 3, subfamily a, polypeptide 41B
chr7_-_4397705 3.374 ENSMUST00000108590.2
Gp6
glycoprotein 6 (platelet)
chr11_+_104577281 3.167 ENSMUST00000106956.3
Myl4
myosin, light polypeptide 4
chr11_+_69098937 3.066 ENSMUST00000021271.7
Per1
period circadian clock 1
chr11_+_104576965 3.031 ENSMUST00000106957.1
Myl4
myosin, light polypeptide 4
chr17_+_47593516 2.911 ENSMUST00000182874.1
Ccnd3
cyclin D3
chr6_-_122801639 2.867 ENSMUST00000165884.1
Slc2a3
solute carrier family 2 (facilitated glucose transporter), member 3
chr2_-_164779721 2.842 ENSMUST00000103095.4
Tnnc2
troponin C2, fast
chr6_-_69243445 2.782 ENSMUST00000101325.3
Igkv4-71
immunoglobulin kappa chain variable 4-71
chr11_-_69948145 2.707 ENSMUST00000179298.1
ENSMUST00000018710.6
ENSMUST00000135437.1
ENSMUST00000141837.2
ENSMUST00000142500.1
Slc2a4




solute carrier family 2 (facilitated glucose transporter), member 4




chr2_-_62483637 2.686 ENSMUST00000136686.1
ENSMUST00000102733.3
Gcg

glucagon

chr4_-_44710408 2.663 ENSMUST00000134968.2
ENSMUST00000173821.1
ENSMUST00000174319.1
ENSMUST00000173733.1
ENSMUST00000172866.1
ENSMUST00000165417.2
ENSMUST00000107825.2
ENSMUST00000102932.3
ENSMUST00000107827.2
ENSMUST00000107826.2
Pax5









paired box gene 5









chr15_-_75111684 2.561 ENSMUST00000100542.3
Ly6c2
lymphocyte antigen 6 complex, locus C2
chr11_-_70352029 2.539 ENSMUST00000019068.6
Alox15
arachidonate 15-lipoxygenase
chr14_-_60197173 2.514 ENSMUST00000131670.1
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr1_-_90153396 2.504 ENSMUST00000113094.2
Iqca
IQ motif containing with AAA domain
chr8_+_21734490 2.498 ENSMUST00000080533.5
Defa24
defensin, alpha, 24
chr15_-_101491509 2.424 ENSMUST00000023718.7
5430421N21Rik
RIKEN cDNA 5430421N21 gene
chr3_-_98814434 2.359 ENSMUST00000029463.6
Hsd3b6
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6
chr1_+_170644523 2.320 ENSMUST00000046792.8
Olfml2b
olfactomedin-like 2B
chr17_-_7352696 2.213 ENSMUST00000115747.1
Ttll2
tubulin tyrosine ligase-like family, member 2
chr2_-_163087770 2.205 ENSMUST00000094653.4
Gtsf1l
gametocyte specific factor 1-like
chr3_-_116253467 2.163 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr11_+_58379036 2.083 ENSMUST00000013787.4
ENSMUST00000108826.2
Lypd8

LY6/PLAUR domain containing 8

chr9_-_123968683 2.078 ENSMUST00000026911.4
Ccr1
chemokine (C-C motif) receptor 1
chr14_-_56262233 2.059 ENSMUST00000015581.4
Gzmb
granzyme B
chr16_+_32756336 2.013 ENSMUST00000135753.1
Muc4
mucin 4
chr8_-_72009619 1.923 ENSMUST00000003574.4
Cyp4f18
cytochrome P450, family 4, subfamily f, polypeptide 18
chr1_+_172555932 1.919 ENSMUST00000061835.3
Vsig8
V-set and immunoglobulin domain containing 8
chr4_-_49408042 1.867 ENSMUST00000081541.2
Acnat2
acyl-coenzyme A amino acid N-acyltransferase 2
chr17_-_43543639 1.865 ENSMUST00000178772.1
Ankrd66
ankyrin repeat domain 66
chr6_+_29433248 1.848 ENSMUST00000101617.2
ENSMUST00000065090.5
Flnc

filamin C, gamma

chr8_+_21134610 1.831 ENSMUST00000098898.4
Gm15284
predicted gene 15284
chr13_+_99100698 1.807 ENSMUST00000181742.1
Gm807
predicted gene 807
chr8_-_64693027 1.788 ENSMUST00000048967.7
Cpe
carboxypeptidase E
chr10_-_117282262 1.787 ENSMUST00000092163.7
Lyz2
lysozyme 2
chr8_-_21594508 1.770 ENSMUST00000110749.3
Gm7861
predicted gene 7861
chr13_+_108316332 1.756 ENSMUST00000051594.5
Depdc1b
DEP domain containing 1B
chr6_-_136922169 1.744 ENSMUST00000032343.6
Erp27
endoplasmic reticulum protein 27
chr15_+_80097866 1.738 ENSMUST00000143928.1
Syngr1
synaptogyrin 1
chr2_-_156839790 1.733 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
Gm14230


predicted gene 14230


chr13_-_37049203 1.698 ENSMUST00000037491.8
F13a1
coagulation factor XIII, A1 subunit
chr13_+_108316395 1.698 ENSMUST00000171178.1
Depdc1b
DEP domain containing 1B
chr11_+_96931387 1.688 ENSMUST00000107633.1
Prr15l
proline rich 15-like
chr6_-_123289862 1.652 ENSMUST00000032239.4
ENSMUST00000177367.1
Clec4e

C-type lectin domain family 4, member e

chr6_+_29433131 1.641 ENSMUST00000090474.4
Flnc
filamin C, gamma
chr16_-_92697315 1.628 ENSMUST00000168195.1
ENSMUST00000113956.3
Runx1

runt related transcription factor 1

chr8_-_21096050 1.621 ENSMUST00000077452.3
Gm14851
predicted gene 14851
chr8_+_123186235 1.615 ENSMUST00000019422.4
Dpep1
dipeptidase 1 (renal)
chr9_+_119052863 1.603 ENSMUST00000131647.1
Vill
villin-like
chr5_+_44100442 1.602 ENSMUST00000072800.4
Gm16401
predicted gene 16401
chr12_+_84100654 1.594 ENSMUST00000056822.3
Acot6
acyl-CoA thioesterase 6
chr12_-_28582515 1.575 ENSMUST00000110917.1
ENSMUST00000020965.7
Allc

allantoicase

chr14_+_65806066 1.563 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr15_-_41869703 1.562 ENSMUST00000054742.5
Abra
actin-binding Rho activating protein
chr8_+_110919916 1.551 ENSMUST00000117534.1
ENSMUST00000034197.4
St3gal2

ST3 beta-galactoside alpha-2,3-sialyltransferase 2

chr17_+_17887840 1.550 ENSMUST00000064068.4
ENSMUST00000054871.5
Fpr2
Fpr3
formyl peptide receptor 2
formyl peptide receptor 3
chr15_-_103252810 1.520 ENSMUST00000154510.1
Nfe2
nuclear factor, erythroid derived 2
chr7_+_28982832 1.516 ENSMUST00000085835.6
Map4k1
mitogen-activated protein kinase kinase kinase kinase 1
chr8_+_21655780 1.515 ENSMUST00000079528.5
Defa17
defensin, alpha, 17
chr6_+_127887582 1.477 ENSMUST00000032501.4
Tspan11
tetraspanin 11
chr17_+_35567450 1.463 ENSMUST00000044326.4
2300002M23Rik
RIKEN cDNA 2300002M23 gene
chrX_+_49463926 1.457 ENSMUST00000130558.1
Arhgap36
Rho GTPase activating protein 36
chr7_+_43440782 1.445 ENSMUST00000040227.1
Cldnd2
claudin domain containing 2
chr8_-_46211284 1.433 ENSMUST00000034049.4
Slc25a4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr8_-_21456560 1.419 ENSMUST00000110752.3
Gm7849
predicted gene 7849
chr8_+_21287409 1.415 ENSMUST00000098893.3
Defa3
defensin, alpha, 3
chr17_+_47593444 1.408 ENSMUST00000182209.1
Ccnd3
cyclin D3
chr5_+_122206792 1.405 ENSMUST00000145854.1
Hvcn1
hydrogen voltage-gated channel 1
chr2_-_129297205 1.400 ENSMUST00000052708.6
Ckap2l
cytoskeleton associated protein 2-like
chr2_+_14873656 1.393 ENSMUST00000114718.1
ENSMUST00000114719.1
Cacnb2

calcium channel, voltage-dependent, beta 2 subunit

chr4_-_149137536 1.391 ENSMUST00000176124.1
ENSMUST00000177408.1
ENSMUST00000105695.1
ENSMUST00000030813.3
Apitd1



apoptosis-inducing, TAF9-like domain 1



chr8_-_21703642 1.363 ENSMUST00000071886.6
AY761184
cDNA sequence AY761184
chr8_-_104624266 1.361 ENSMUST00000163783.2
Cdh16
cadherin 16
chr8_+_21055047 1.349 ENSMUST00000098899.3
Defa23
defensin, alpha, 23
chr19_-_45812291 1.301 ENSMUST00000086993.4
Kcnip2
Kv channel-interacting protein 2
chr17_+_56764738 1.289 ENSMUST00000007747.8
Dus3l
dihydrouridine synthase 3-like (S. cerevisiae)
chr4_+_150927918 1.286 ENSMUST00000139826.1
ENSMUST00000116257.1
Tnfrsf9

tumor necrosis factor receptor superfamily, member 9

chr8_+_21191614 1.278 ENSMUST00000098896.4
Defa-rs7
defensin, alpha, related sequence 7
chr1_-_14755966 1.273 ENSMUST00000027062.5
Msc
musculin
chr11_-_87108656 1.271 ENSMUST00000051395.8
Prr11
proline rich 11
chr8_+_84148252 1.266 ENSMUST00000093375.4
4930432K21Rik
RIKEN cDNA 4930432K21 gene
chr2_-_29869785 1.204 ENSMUST00000047607.1
2600006K01Rik
RIKEN cDNA 2600006K01 gene
chr11_-_69822144 1.191 ENSMUST00000045771.6
Spem1
sperm maturation 1
chr6_+_49036518 1.179 ENSMUST00000031840.7
Gpnmb
glycoprotein (transmembrane) nmb
chr3_+_152165374 1.177 ENSMUST00000181854.1
D630002J18Rik
RIKEN cDNA D630002J18 gene
chr3_-_129969989 1.176 ENSMUST00000146340.1
Ccdc109b
coiled-coil domain containing 109B
chr4_+_11123950 1.166 ENSMUST00000142297.1
Gm11827
predicted gene 11827
chrX_+_134308084 1.164 ENSMUST00000081064.5
ENSMUST00000101251.1
ENSMUST00000129782.1
Cenpi


centromere protein I


chr7_+_12922290 1.164 ENSMUST00000108539.1
ENSMUST00000004554.7
ENSMUST00000147435.1
ENSMUST00000137329.1
Rps5



ribosomal protein S5



chr12_+_104406704 1.123 ENSMUST00000021506.5
Serpina3n
serine (or cysteine) peptidase inhibitor, clade A, member 3N
chr7_-_45092198 1.118 ENSMUST00000140449.1
ENSMUST00000117546.1
ENSMUST00000019683.3
Rcn3


reticulocalbin 3, EF-hand calcium binding domain


chr6_-_69400097 1.111 ENSMUST00000177795.1
Igkv4-62
immunoglobulin kappa variable 4-62
chr2_+_25423234 1.103 ENSMUST00000134259.1
ENSMUST00000100320.4
Fut7

fucosyltransferase 7

chr2_+_152427639 1.098 ENSMUST00000128737.1
6820408C15Rik
RIKEN cDNA 6820408C15 gene
chr2_+_26319741 1.094 ENSMUST00000066889.6
Gpsm1
G-protein signalling modulator 1 (AGS3-like, C. elegans)
chr5_+_141856692 1.090 ENSMUST00000074546.6
Sdk1
sidekick homolog 1 (chicken)
chr2_-_24935148 1.083 ENSMUST00000102935.3
ENSMUST00000133934.1
ENSMUST00000028349.7
Arrdc1


arrestin domain containing 1


chr11_-_106160708 1.076 ENSMUST00000106875.1
Limd2
LIM domain containing 2
chr2_-_122298165 1.059 ENSMUST00000053734.5
Duox2
dual oxidase 2
chr17_-_45549655 1.058 ENSMUST00000180252.1
Tmem151b
transmembrane protein 151B
chr10_+_75954514 1.048 ENSMUST00000099577.3
Gm5134
predicted gene 5134
chr11_+_69964758 1.044 ENSMUST00000108597.1
ENSMUST00000060651.5
ENSMUST00000108596.1
Cldn7


claudin 7


chr5_+_25246775 1.036 ENSMUST00000144971.1
Galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chr11_+_98386450 1.022 ENSMUST00000041301.7
Pnmt
phenylethanolamine-N-methyltransferase
chr11_+_94936224 1.021 ENSMUST00000001547.7
Col1a1
collagen, type I, alpha 1
chr9_-_20959785 1.020 ENSMUST00000177754.1
Dnmt1
DNA methyltransferase (cytosine-5) 1
chr11_+_108395288 1.017 ENSMUST00000000049.5
Apoh
apolipoprotein H
chr7_-_44974781 1.012 ENSMUST00000063761.7
Cpt1c
carnitine palmitoyltransferase 1c
chr8_+_71406003 1.010 ENSMUST00000119976.1
ENSMUST00000120725.1
Ankle1

ankyrin repeat and LEM domain containing 1

chr2_+_136057927 1.006 ENSMUST00000057503.6
Lamp5
lysosomal-associated membrane protein family, member 5
chr6_+_34476207 1.001 ENSMUST00000045372.5
ENSMUST00000138668.1
ENSMUST00000139067.1
Bpgm


2,3-bisphosphoglycerate mutase


chr5_+_17574726 1.001 ENSMUST00000169603.1
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr2_-_150179679 0.978 ENSMUST00000099418.2
Gm10770
predicted gene 10770
chr4_+_116708571 0.977 ENSMUST00000106462.2
ENSMUST00000138305.1
ENSMUST00000125671.1
ENSMUST00000130828.1
Ccdc163



coiled-coil domain containing 163



chr10_-_32410335 0.975 ENSMUST00000092603.4
Nkain2
Na+/K+ transporting ATPase interacting 2
chr5_-_140321524 0.968 ENSMUST00000031534.6
Mad1l1
MAD1 mitotic arrest deficient 1-like 1
chr10_-_86732409 0.958 ENSMUST00000070435.4
Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr2_-_132029845 0.955 ENSMUST00000028814.8
Rassf2
Ras association (RalGDS/AF-6) domain family member 2
chr6_+_5725639 0.952 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr1_+_91540553 0.952 ENSMUST00000027538.7
Asb1
ankyrin repeat and SOCS box-containing 1
chr7_-_81566939 0.951 ENSMUST00000042318.5
Fsd2
fibronectin type III and SPRY domain containing 2
chr2_+_109280738 0.944 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr16_-_45693658 0.939 ENSMUST00000114562.2
ENSMUST00000036617.7
Tmprss7

transmembrane serine protease 7

chr7_-_45092130 0.921 ENSMUST00000148175.1
Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr8_+_94745590 0.920 ENSMUST00000034231.3
Ccl22
chemokine (C-C motif) ligand 22
chr4_-_149909719 0.913 ENSMUST00000105685.1
Spsb1
splA/ryanodine receptor domain and SOCS box containing 1
chr7_+_16992708 0.911 ENSMUST00000094805.4
Ccdc8
coiled-coil domain containing 8
chr3_-_144760841 0.911 ENSMUST00000059091.5
Clca1
chloride channel calcium activated 1
chr18_+_65580230 0.902 ENSMUST00000049016.5
ENSMUST00000183236.1
Zfp532

zinc finger protein 532

chr17_+_56256793 0.890 ENSMUST00000060253.3
Fem1a
feminization 1 homolog a (C. elegans)
chr8_+_95703037 0.885 ENSMUST00000073139.7
ENSMUST00000080666.7
Ndrg4

N-myc downstream regulated gene 4

chr11_-_75439551 0.884 ENSMUST00000128330.1
Serpinf2
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr1_-_133801031 0.881 ENSMUST00000143567.1
Atp2b4
ATPase, Ca++ transporting, plasma membrane 4
chr5_+_110879788 0.862 ENSMUST00000156290.2
ENSMUST00000040111.9
Ttc28

tetratricopeptide repeat domain 28

chr4_+_12906838 0.859 ENSMUST00000143186.1
ENSMUST00000183345.1
Triqk

triple QxxK/R motif containing

chr1_-_163289214 0.859 ENSMUST00000183691.1
Prrx1
paired related homeobox 1
chr14_+_32159865 0.859 ENSMUST00000163336.1
ENSMUST00000169722.1
ENSMUST00000168385.1
Ncoa4


nuclear receptor coactivator 4


chr15_-_85821733 0.854 ENSMUST00000064370.4
Pkdrej
polycystic kidney disease (polycystin) and REJ (sperm receptor for egg jelly homolog, sea urchin)
chr1_+_174041933 0.842 ENSMUST00000052975.4
Olfr433
olfactory receptor 433
chr4_+_116708624 0.840 ENSMUST00000106463.1
Ccdc163
coiled-coil domain containing 163
chr4_+_116708687 0.834 ENSMUST00000135499.1
Ccdc163
coiled-coil domain containing 163
chr9_+_56865104 0.825 ENSMUST00000035661.5
Cspg4
chondroitin sulfate proteoglycan 4
chr4_+_135911808 0.810 ENSMUST00000068830.3
Cnr2
cannabinoid receptor 2 (macrophage)
chr14_-_32685246 0.805 ENSMUST00000096038.3
3425401B19Rik
RIKEN cDNA 3425401B19 gene
chr11_-_98053415 0.796 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr14_+_53683593 0.795 ENSMUST00000103663.4
Trav4-4-dv10
T cell receptor alpha variable 4-4-DV10
chr7_-_46179929 0.792 ENSMUST00000033123.6
Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr18_+_36679575 0.789 ENSMUST00000050476.4
ENSMUST00000036158.6
Slc35a4

solute carrier family 35, member A4

chr1_-_170589791 0.779 ENSMUST00000161966.1
ENSMUST00000160456.1
Nos1ap

nitric oxide synthase 1 (neuronal) adaptor protein

chr5_-_122697603 0.776 ENSMUST00000071235.4
Gm10064
predicted gene 10064
chr4_-_44704006 0.753 ENSMUST00000146335.1
Pax5
paired box gene 5
chr17_-_36020525 0.747 ENSMUST00000174063.1
ENSMUST00000113760.3
H2-T24

histocompatibility 2, T region locus 24

chr17_-_47924460 0.741 ENSMUST00000113262.1
Foxp4
forkhead box P4
chr11_-_99155067 0.729 ENSMUST00000103134.3
Ccr7
chemokine (C-C motif) receptor 7
chr2_-_24935054 0.727 ENSMUST00000132074.1
Arrdc1
arrestin domain containing 1
chr11_+_61208621 0.727 ENSMUST00000108716.1
ENSMUST00000019246.3
Aldh3a1

aldehyde dehydrogenase family 3, subfamily A1

chr10_+_128411616 0.722 ENSMUST00000096386.5
ENSMUST00000171342.1
Rnf41

ring finger protein 41

chr7_-_46672537 0.713 ENSMUST00000049298.7
Tph1
tryptophan hydroxylase 1
chr2_-_126618655 0.711 ENSMUST00000028838.4
Hdc
histidine decarboxylase
chr18_+_64254359 0.711 ENSMUST00000025477.7
St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr11_-_33578933 0.706 ENSMUST00000020366.1
ENSMUST00000135350.1
Gabrp

gamma-aminobutyric acid (GABA) A receptor, pi

chr13_-_59675754 0.705 ENSMUST00000022039.5
ENSMUST00000095739.2
Golm1

golgi membrane protein 1

chr2_+_158512796 0.701 ENSMUST00000099133.3
ENSMUST00000165398.1
Arhgap40

Rho GTPase activating protein 40

chr14_+_66784523 0.692 ENSMUST00000071522.2
Gm10032
predicted gene 10032
chr14_-_6742332 0.690 ENSMUST00000163850.1
Gm3636
predicted gene 3636
chr4_-_111902754 0.687 ENSMUST00000102719.1
ENSMUST00000102721.1
Slc5a9

solute carrier family 5 (sodium/glucose cotransporter), member 9

chrX_+_37804842 0.686 ENSMUST00000184866.1
ENSMUST00000179626.1
Rhox5

reproductive homeobox 5

chr5_+_47984571 0.678 ENSMUST00000174313.1
Slit2
slit homolog 2 (Drosophila)
chr11_-_75439489 0.667 ENSMUST00000043696.2
Serpinf2
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr2_-_118728430 0.663 ENSMUST00000102524.1
Plcb2
phospholipase C, beta 2
chr14_-_70331514 0.656 ENSMUST00000139284.1
Slc39a14
solute carrier family 39 (zinc transporter), member 14
chr2_-_10130638 0.654 ENSMUST00000042290.7
Itih2
inter-alpha trypsin inhibitor, heavy chain 2
chr6_+_135362931 0.647 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chr4_+_109978004 0.646 ENSMUST00000061187.3
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr19_+_10937154 0.644 ENSMUST00000037261.3
Gpr44
G protein-coupled receptor 44
chr7_+_118600152 0.634 ENSMUST00000121744.1
Tmc5
transmembrane channel-like gene family 5
chr11_+_69125896 0.625 ENSMUST00000021268.2
Aloxe3
arachidonate lipoxygenase 3
chr17_-_47924400 0.624 ENSMUST00000113263.1
ENSMUST00000097311.2
Foxp4

forkhead box P4

chr14_-_6875155 0.623 ENSMUST00000170465.2
Gm3636
predicted gene 3636
chr18_-_78057395 0.622 ENSMUST00000170760.2
Siglec15
sialic acid binding Ig-like lectin 15
chr3_-_30647793 0.617 ENSMUST00000029252.7
Lrrc34
leucine rich repeat containing 34
chr1_-_144249134 0.617 ENSMUST00000172388.1
Rgs1
regulator of G-protein signaling 1
chr6_+_29279587 0.616 ENSMUST00000167131.1
Fam71f2
family with sequence similarity 71, member F2
chr8_-_13254154 0.616 ENSMUST00000033825.4
Adprhl1
ADP-ribosylhydrolase like 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.8 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
1.7 6.6 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
1.4 1.4 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
1.1 3.4 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.0 14.0 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.8 2.5 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.8 6.6 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.7 4.8 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.6 1.9 GO:1901662 menaquinone metabolic process(GO:0009233) phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.6 3.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.6 2.9 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.5 1.6 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.5 2.2 GO:0061743 motor learning(GO:0061743)
0.5 3.4 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.5 1.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.5 3.6 GO:0061789 dense core granule priming(GO:0061789)
0.4 1.8 GO:0030070 insulin processing(GO:0030070)
0.4 0.9 GO:2000282 regulation of cellular amino acid biosynthetic process(GO:2000282)
0.4 2.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.4 2.7 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.3 1.0 GO:0042414 epinephrine metabolic process(GO:0042414)
0.3 2.0 GO:0002838 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.3 1.3 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.3 1.3 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.3 2.5 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.3 2.6 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.3 1.1 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.3 0.8 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.3 0.5 GO:0051885 positive regulation of timing of anagen(GO:0051885)
0.3 1.3 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.3 1.0 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 0.7 GO:2000547 lymphocyte migration into lymphoid organs(GO:0097021) positive regulation of thymocyte migration(GO:2000412) regulation of immunological synapse formation(GO:2000520) regulation of dendritic cell dendrite assembly(GO:2000547)
0.2 0.7 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.2 4.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 1.0 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.2 1.0 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.2 1.6 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.2 1.0 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.2 4.4 GO:1904659 glucose transmembrane transport(GO:1904659)
0.2 0.6 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.2 0.5 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.2 0.5 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.2 0.7 GO:1990743 protein sialylation(GO:1990743)
0.2 4.0 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.2 1.7 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.2 0.8 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.2 1.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.2 0.6 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.2 0.5 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.2 1.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.2 3.4 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.2 6.2 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.2 1.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 1.7 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.1 1.6 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 1.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.7 GO:0001692 histamine metabolic process(GO:0001692) histidine catabolic process(GO:0006548)
0.1 1.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 3.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 0.1 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.1 1.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 1.4 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.1 0.6 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 1.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.7 GO:1901525 negative regulation of mitophagy(GO:1901525)
0.1 0.6 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 1.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.8 GO:0032056 positive regulation of translation in response to stress(GO:0032056)
0.1 0.6 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 1.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.3 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 0.8 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1 0.5 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.7 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 1.6 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 0.4 GO:0035811 negative regulation of urine volume(GO:0035811)
0.1 0.7 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.1 6.2 GO:0070988 demethylation(GO:0070988)
0.1 0.4 GO:0009597 detection of virus(GO:0009597) positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.9 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.1 0.3 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.1 0.7 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 1.0 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 1.0 GO:0009437 carnitine metabolic process(GO:0009437)
0.1 0.3 GO:0050904 diapedesis(GO:0050904)
0.1 2.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.6 GO:2001204 regulation of osteoclast development(GO:2001204)
0.1 1.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.2 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.1 0.8 GO:0016322 neuron remodeling(GO:0016322)
0.1 1.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.9 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.2 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.2 GO:0033189 response to vitamin A(GO:0033189)
0.1 0.9 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 1.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.2 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.2 GO:1905937 negative regulation of germ cell proliferation(GO:1905937) negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.3 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.0 0.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 3.3 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 1.2 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.6 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0030473 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
0.0 0.9 GO:0048148 behavioral response to cocaine(GO:0048148)
0.0 0.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 1.2 GO:0034508 centromere complex assembly(GO:0034508)
0.0 0.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 2.0 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 4.0 GO:0002377 immunoglobulin production(GO:0002377)
0.0 1.0 GO:0030539 male genitalia development(GO:0030539)
0.0 0.1 GO:0060025 regulation of synaptic activity(GO:0060025)
0.0 0.5 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.6 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.4 GO:0043486 histone exchange(GO:0043486)
0.0 0.3 GO:0042711 maternal behavior(GO:0042711)
0.0 1.0 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.0 0.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.0 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 1.3 GO:0051693 actin filament capping(GO:0051693)
0.0 0.1 GO:0021837 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) regulation of mitotic cell cycle DNA replication(GO:1903463) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.0 0.3 GO:0046641 positive regulation of alpha-beta T cell proliferation(GO:0046641)
0.0 0.5 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 1.4 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.8 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 3.1 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.0 0.3 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.0 0.2 GO:0099515 actin filament-based transport(GO:0099515)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.8 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.2 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343) positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.4 GO:0030073 insulin secretion(GO:0030073)
0.0 0.6 GO:0016049 cell growth(GO:0016049)
0.0 0.4 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.0 0.2 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 0.4 GO:0072678 T cell migration(GO:0072678)
0.0 1.2 GO:0030317 flagellated sperm motility(GO:0030317)
0.0 0.2 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.6 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.3 GO:0050804 modulation of chemical synaptic transmission(GO:0050804)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.1 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.8 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.3 GO:0006760 folic acid-containing compound metabolic process(GO:0006760)
0.0 0.2 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0044194 cytolytic granule(GO:0044194)
0.5 8.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.5 14.9 GO:0042588 zymogen granule(GO:0042588)
0.4 1.3 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.4 1.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.3 1.0 GO:0005584 collagen type I trimer(GO:0005584)
0.3 3.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 3.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 2.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 0.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 1.6 GO:0005577 fibrinogen complex(GO:0005577)
0.2 2.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 2.8 GO:0005861 troponin complex(GO:0005861)
0.2 0.9 GO:1990393 3M complex(GO:1990393)
0.1 1.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.8 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.6 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 1.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.8 GO:0031045 dense core granule(GO:0031045)
0.1 2.9 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.3 GO:0031074 nucleocytoplasmic transport complex(GO:0031074)
0.1 6.4 GO:0031672 A band(GO:0031672)
0.1 2.0 GO:0031528 microvillus membrane(GO:0031528)
0.1 7.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.9 GO:0044754 autolysosome(GO:0044754)
0.1 1.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 3.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 1.0 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 2.6 GO:0031970 organelle envelope lumen(GO:0031970)
0.0 0.9 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.0 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 1.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.6 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:1990696 USH2 complex(GO:1990696)
0.0 5.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.4 GO:0001527 microfibril(GO:0001527)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 1.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.0 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 3.0 GO:0072562 blood microparticle(GO:0072562)
0.0 1.8 GO:0016528 sarcoplasm(GO:0016528)
0.0 3.1 GO:0001650 fibrillar center(GO:0001650)
0.0 2.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.6 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.6 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 5.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789) endoplasmic reticulum subcompartment(GO:0098827)
0.0 1.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 14.0 GO:0004771 sterol esterase activity(GO:0004771) retinyl-palmitate esterase activity(GO:0050253)
2.6 7.8 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
1.1 5.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.9 6.9 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.8 6.6 GO:0002951 leukotriene-C(4) hydrolase(GO:0002951)
0.7 2.1 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.6 1.9 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
0.6 2.5 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.5 2.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.5 1.4 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.4 1.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.4 1.5 GO:0070052 collagen V binding(GO:0070052)
0.3 1.0 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.3 2.4 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.3 3.4 GO:0038064 collagen receptor activity(GO:0038064)
0.3 1.4 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.3 1.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 3.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.3 1.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.3 1.6 GO:0005124 scavenger receptor binding(GO:0005124)
0.3 1.0 GO:0070573 metallodipeptidase activity(GO:0070573)
0.2 1.0 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.2 0.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2 0.7 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 1.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2 0.6 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.2 1.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 0.5 GO:0070737 protein-glycine ligase activity, elongating(GO:0070737)
0.2 0.7 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.2 0.5 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2 1.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 1.2 GO:0045545 syndecan binding(GO:0045545)
0.1 1.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 6.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.8 GO:0003796 lysozyme activity(GO:0003796)
0.1 1.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.4 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 3.5 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 1.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.6 GO:0070728 leucine binding(GO:0070728)
0.1 0.7 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 1.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 1.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.4 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.3 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 0.7 GO:0048495 GTPase inhibitor activity(GO:0005095) Roundabout binding(GO:0048495)
0.1 0.3 GO:0099103 channel activator activity(GO:0099103) potassium channel activator activity(GO:0099104)
0.1 0.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 2.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 3.1 GO:0030506 ankyrin binding(GO:0030506)
0.1 6.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 1.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.8 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.2 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.1 0.9 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 1.0 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.4 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 4.7 GO:0005507 copper ion binding(GO:0005507)
0.1 1.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 3.1 GO:0070888 E-box binding(GO:0070888)
0.0 1.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.6 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.4 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.6 GO:0043495 protein membrane anchor(GO:0043495)
0.0 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.8 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 1.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.9 GO:0008009 chemokine activity(GO:0008009)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 2.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.4 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) L-serine transporter activity(GO:1905361)
0.0 5.2 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.0 0.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.8 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229) intracellular chloride channel activity(GO:0061778)
0.0 2.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.3 GO:0043022 ribosome binding(GO:0043022)
0.0 3.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 2.7 GO:0002020 protease binding(GO:0002020)
0.0 0.8 GO:0005518 collagen binding(GO:0005518)
0.0 5.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 2.2 GO:0003774 motor activity(GO:0003774)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.2 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 1.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 2.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0019841 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.0 0.1 GO:0090722 receptor-receptor interaction(GO:0090722)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 1.5 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 0.6 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.9 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 3.8 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 3.5 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 3.6 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 1.9 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.7 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.7 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 1.3 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 2.1 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.0 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 3.2 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 1.4 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 1.3 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 4.9 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.7 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 1.0 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.2 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 1.2 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 1.0 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.6 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 9.0 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.2 3.6 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.7 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 3.5 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.4 REACTOME_DEFENSINS Genes involved in Defensins
0.1 1.6 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.1 3.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.8 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.0 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.4 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 3.1 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 1.0 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.7 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.8 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 0.6 REACTOME_PROSTANOID_LIGAND_RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 0.7 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 1.4 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 1.8 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 4.3 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.9 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.7 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.3 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.2 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.6 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.6 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.0 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.2 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.9 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.9 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.5 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.8 REACTOME_REGULATION_OF_INSULIN_SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 2.8 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.7 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.1 REACTOME_OPSINS Genes involved in Opsins
0.0 0.4 REACTOME_GLUCOSE_METABOLISM Genes involved in Glucose metabolism