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GSE58827: Dynamics of the Mouse Liver

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Results for Barhl1

Z-value: 0.46

Motif logo

Transcription factors associated with Barhl1

Gene Symbol Gene ID Gene Info
ENSMUSG00000026805.8 BarH like homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Barhl1mm10_v2_chr2_-_28916412_28916440-0.202.5e-01Click!

Activity profile of Barhl1 motif

Sorted Z-values of Barhl1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_90490714 3.99 ENSMUST00000042755.3
alpha fetoprotein
chr17_+_7025837 2.58 ENSMUST00000089120.5
predicted gene 1604b
chr17_-_8101228 2.25 ENSMUST00000097422.4
predicted gene 1604A
chr3_-_75270073 1.70 ENSMUST00000039047.4
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr19_-_34166037 1.63 ENSMUST00000025686.7
ankyrin repeat domain 22
chr8_+_31089471 1.27 ENSMUST00000036631.7
ENSMUST00000170204.1
dual specificity phosphatase 26 (putative)
chr1_-_75278345 1.25 ENSMUST00000039534.4
regulated endocrine-specific protein 18
chr6_-_129876659 1.23 ENSMUST00000014687.4
ENSMUST00000122219.1
killer cell lectin-like receptor, subfamily A, member 17
chr18_-_32559914 0.87 ENSMUST00000174000.1
ENSMUST00000174459.1
glycophorin C
chr6_+_123123423 0.86 ENSMUST00000032248.7
C-type lectin domain family 4, member a2
chr7_+_30763750 0.80 ENSMUST00000165887.1
ENSMUST00000085691.4
ENSMUST00000085688.4
ENSMUST00000054427.6
dermokine
chr18_+_53551594 0.76 ENSMUST00000115398.1
PR domain containing 6
chrX_-_164250368 0.71 ENSMUST00000112263.1
BMX non-receptor tyrosine kinase
chr6_-_41636389 0.71 ENSMUST00000031902.5
transient receptor potential cation channel, subfamily V, member 6
chr11_+_116198853 0.62 ENSMUST00000021130.6
TEN1 telomerase capping complex subunit
chr2_-_45110336 0.52 ENSMUST00000028229.6
ENSMUST00000152232.1
zinc finger E-box binding homeobox 2
chrX_+_112604274 0.51 ENSMUST00000071814.6
zinc finger protein 711
chr6_+_72097561 0.51 ENSMUST00000069994.4
ENSMUST00000114112.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr9_+_36832684 0.50 ENSMUST00000034630.8
fasciculation and elongation protein zeta 1 (zygin I)
chr7_-_45896656 0.48 ENSMUST00000120299.1
synaptogyrin 4
chrX_+_109196750 0.47 ENSMUST00000139259.1
ENSMUST00000060013.3
predicted gene 6377
chr8_-_84840627 0.46 ENSMUST00000003911.6
ENSMUST00000109761.2
ENSMUST00000128035.1
RAD23a homolog (S. cerevisiae)
chr11_+_89073841 0.43 ENSMUST00000100619.4
predicted gene 525
chr5_+_149678224 0.43 ENSMUST00000100404.3
beta 1,3-galactosyltransferase-like
chr4_-_117156144 0.42 ENSMUST00000102696.4
ribosomal protein S8
chr1_-_63214543 0.41 ENSMUST00000050536.7
G protein-coupled receptor 1
chr7_+_97842917 0.40 ENSMUST00000033040.5
p21 protein (Cdc42/Rac)-activated kinase 1
chr15_+_101473472 0.40 ENSMUST00000088049.3
keratin 86
chr2_-_104849876 0.38 ENSMUST00000028593.4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr6_+_129591782 0.35 ENSMUST00000112063.2
ENSMUST00000032268.7
ENSMUST00000119520.1
killer cell lectin-like receptor, subfamily D, member 1
chr2_-_73453918 0.33 ENSMUST00000102679.1
WAS/WASL interacting protein family, member 1
chr2_+_122426432 0.32 ENSMUST00000110525.1
solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
chr4_+_112232245 0.30 ENSMUST00000038455.5
ENSMUST00000170945.1
selection and upkeep of intraepithelial T cells 3
chr14_+_25980039 0.29 ENSMUST00000173155.1
double homeobox B-like 1
chr5_-_104077608 0.23 ENSMUST00000164471.1
ENSMUST00000178967.1
predicted gene, 17660
chr7_-_45896677 0.23 ENSMUST00000039049.7
synaptogyrin 4
chrX_-_75578188 0.22 ENSMUST00000033545.5
RAB39B, member RAS oncogene family
chr3_-_19265007 0.19 ENSMUST00000091314.4
phosphodiesterase 7A
chr3_-_130709419 0.19 ENSMUST00000043937.7
oligosaccharyltransferase complex subunit
chr10_+_128747850 0.18 ENSMUST00000163377.2
within bgcn homolog (Drosophila)
chr3_-_19264959 0.16 ENSMUST00000121951.1
phosphodiesterase 7A
chr5_+_138187485 0.16 ENSMUST00000110934.2
canopy 4 homolog (zebrafish)
chr14_+_63860290 0.15 ENSMUST00000022528.4
PIN2/TERF1 interacting, telomerase inhibitor 1
chr13_+_19342154 0.13 ENSMUST00000103566.3
T cell receptor gamma, constant 4
chr16_+_92292380 0.12 ENSMUST00000047383.3
potassium voltage-gated channel, Isk-related subfamily, gene 2
chr18_+_12972225 0.11 ENSMUST00000025290.5
imprinted and ancient
chr5_+_34915915 0.10 ENSMUST00000050535.1
Myb/SANT-like DNA-binding domain containing 1
chr3_-_88410295 0.09 ENSMUST00000056370.7
polyamine-modulated factor 1
chr11_+_78826575 0.09 ENSMUST00000147875.2
ENSMUST00000141321.1
LYR motif containing 9
chr10_+_102159000 0.08 ENSMUST00000020039.6
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr15_+_81744848 0.08 ENSMUST00000109554.1
zinc finger CCCH type containing 7B
chr2_-_177921815 0.08 ENSMUST00000108986.2
RIKEN cDNA C330013J21 gene
chr12_-_54795698 0.08 ENSMUST00000005798.8
sorting nexin 6
chr16_-_29544852 0.07 ENSMUST00000039090.8
ATPase type 13A4
chr18_-_42262053 0.07 ENSMUST00000097590.3
leucyl-tRNA synthetase
chr17_+_55892184 0.07 ENSMUST00000054780.8
zinc finger protein 959
chr2_+_27165233 0.06 ENSMUST00000000910.6
dopamine beta hydroxylase
chr10_-_127030813 0.05 ENSMUST00000040560.4
Ts translation elongation factor, mitochondrial
chr10_-_127030789 0.04 ENSMUST00000120547.1
ENSMUST00000152054.1
Ts translation elongation factor, mitochondrial
chr10_+_102158858 0.03 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr1_+_115684727 0.02 ENSMUST00000043725.7
contactin associated protein-like 5A
chr2_-_80128834 0.02 ENSMUST00000102654.4
ENSMUST00000102655.3
phosphodiesterase 1A, calmodulin-dependent
chr17_-_25115905 0.02 ENSMUST00000024987.5
ENSMUST00000115181.2
TEL2, telomere maintenance 2, homolog (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of Barhl1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.2 4.0 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 0.8 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.5 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.4 GO:0021764 amygdala development(GO:0021764) negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.3 GO:1901642 purine nucleoside transmembrane transport(GO:0015860) nucleoside transmembrane transport(GO:1901642)
0.1 0.7 GO:1990035 parathyroid hormone secretion(GO:0035898) calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.8 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 0.2 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.0 0.7 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.6 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.5 GO:0051654 establishment of mitochondrion localization(GO:0051654)
0.0 0.1 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.5 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.5 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.6 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.4 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.4 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.4 1.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.3 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 0.3 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.1 1.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.5 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.5 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions