Motif ID: Creb1

Z-value: 1.441


Transcription factors associated with Creb1:

Gene SymbolEntrez IDGene Name
Creb1 ENSMUSG00000025958.8 Creb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb1mm10_v2_chr1_+_64532790_64532815-0.115.4e-01Click!


Activity profile for motif Creb1.

activity profile for motif Creb1


Sorted Z-values histogram for motif Creb1

Sorted Z-values for motif Creb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Creb1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_55099417 5.078 ENSMUST00000061856.5
Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
chr1_+_185363076 3.191 ENSMUST00000046514.7
Eprs
glutamyl-prolyl-tRNA synthetase
chr12_-_4907705 2.841 ENSMUST00000020962.5
Ubxn2a
UBX domain protein 2A
chr10_+_62920630 2.778 ENSMUST00000044977.3
Slc25a16
solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
chr12_+_108334341 2.615 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr13_-_29984219 2.581 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr14_-_59597836 2.459 ENSMUST00000167100.1
ENSMUST00000022555.4
ENSMUST00000056997.7
ENSMUST00000171683.1
Cdadc1



cytidine and dCMP deaminase domain containing 1



chr10_+_62920648 2.356 ENSMUST00000144459.1
Slc25a16
solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
chr12_-_4907229 2.339 ENSMUST00000142867.1
Ubxn2a
UBX domain protein 2A
chr11_-_86807624 2.265 ENSMUST00000018569.7
Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr8_+_40511769 2.241 ENSMUST00000098817.2
Vps37a
vacuolar protein sorting 37A (yeast)
chr8_+_3621529 2.031 ENSMUST00000156380.2
Pet100
PET100 homolog (S. cerevisiae)
chr11_-_83302586 2.008 ENSMUST00000176374.1
Pex12
peroxisomal biogenesis factor 12
chr13_+_58402546 1.974 ENSMUST00000042450.8
Rmi1
RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)
chrX_-_56598069 1.954 ENSMUST00000059899.2
Mmgt1
membrane magnesium transporter 1
chr1_+_180851131 1.913 ENSMUST00000038091.6
Sde2
SDE2 telomere maintenance homolog (S. pombe)
chr12_+_33429605 1.881 ENSMUST00000020877.7
Twistnb
TWIST neighbor
chr1_+_78657825 1.873 ENSMUST00000035779.8
Acsl3
acyl-CoA synthetase long-chain family member 3
chr12_+_116281180 1.866 ENSMUST00000100986.2
Esyt2
extended synaptotagmin-like protein 2
chr12_+_28751798 1.814 ENSMUST00000035657.7
Tssc1
tumor suppressing subtransferable candidate 1
chr10_+_7792891 1.751 ENSMUST00000015901.4
Ppil4
peptidylprolyl isomerase (cyclophilin)-like 4
chr12_-_57546121 1.674 ENSMUST00000044380.6
Foxa1
forkhead box A1
chr7_+_46796088 1.663 ENSMUST00000006774.4
ENSMUST00000165031.1
Gtf2h1

general transcription factor II H, polypeptide 1

chr1_+_43933980 1.623 ENSMUST00000087933.3
Tpp2
tripeptidyl peptidase II
chr18_+_9958147 1.580 ENSMUST00000025137.7
Thoc1
THO complex 1
chr5_-_112343010 1.558 ENSMUST00000146510.1
ENSMUST00000031289.6
Srrd

SRR1 domain containing

chr16_+_22857845 1.545 ENSMUST00000004574.7
ENSMUST00000178320.1
ENSMUST00000166487.2
Dnajb11


DnaJ (Hsp40) homolog, subfamily B, member 11


chr10_+_44268328 1.508 ENSMUST00000039286.4
Atg5
autophagy related 5
chr8_-_22653406 1.507 ENSMUST00000033938.5
Polb
polymerase (DNA directed), beta
chr8_-_79711631 1.498 ENSMUST00000080536.6
Abce1
ATP-binding cassette, sub-family E (OABP), member 1
chr2_-_119156824 1.490 ENSMUST00000135419.1
ENSMUST00000129351.1
ENSMUST00000139519.1
ENSMUST00000094695.5
Rmdn3



regulator of microtubule dynamics 3



chr8_-_40511298 1.446 ENSMUST00000149992.1
Cnot7
CCR4-NOT transcription complex, subunit 7
chr1_+_78657874 1.421 ENSMUST00000134566.1
ENSMUST00000142704.1
ENSMUST00000053760.5
Acsl3

Utp14b
acyl-CoA synthetase long-chain family member 3

UTP14, U3 small nucleolar ribonucleoprotein, homolog B (yeast)
chr12_+_51377560 1.372 ENSMUST00000021335.5
Scfd1
Sec1 family domain containing 1
chr13_+_98263242 1.366 ENSMUST00000022164.8
ENSMUST00000150352.1
Ankra2

ankyrin repeat, family A (RFXANK-like), 2

chr14_-_31251194 1.355 ENSMUST00000022459.3
Phf7
PHD finger protein 7
chr2_+_144556229 1.328 ENSMUST00000143573.1
ENSMUST00000028916.8
ENSMUST00000155258.1
Sec23b


SEC23B (S. cerevisiae)


chr7_-_118533298 1.324 ENSMUST00000098090.3
ENSMUST00000032887.3
Coq7

demethyl-Q 7

chr4_-_149307506 1.314 ENSMUST00000055647.8
ENSMUST00000030806.5
ENSMUST00000060537.6
Kif1b


kinesin family member 1B


chr12_-_56535047 1.305 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr8_-_40511663 1.301 ENSMUST00000135269.1
ENSMUST00000034012.3
Cnot7

CCR4-NOT transcription complex, subunit 7

chr12_-_108179237 1.300 ENSMUST00000071095.7
Setd3
SET domain containing 3
chr12_-_101083653 1.298 ENSMUST00000048305.8
ENSMUST00000163095.1
Smek1

SMEK homolog 1, suppressor of mek1 (Dictyostelium)

chr9_-_96478660 1.290 ENSMUST00000057500.4
Rnf7
ring finger protein 7
chr8_+_60993189 1.279 ENSMUST00000034065.7
ENSMUST00000120689.1
Nek1

NIMA (never in mitosis gene a)-related expressed kinase 1

chr11_+_95384662 1.273 ENSMUST00000021243.7
ENSMUST00000146556.1
Slc35b1

solute carrier family 35, member B1

chr6_-_4086914 1.261 ENSMUST00000049166.4
Bet1
blocked early in transport 1 homolog (S. cerevisiae)
chr13_+_96542727 1.229 ENSMUST00000077672.4
ENSMUST00000109444.2
Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chrX_+_71816758 1.225 ENSMUST00000114576.2
ENSMUST00000114575.3
Vma21

VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)

chr9_-_96478596 1.217 ENSMUST00000071301.4
Rnf7
ring finger protein 7
chr9_-_53248106 1.204 ENSMUST00000065630.6
Ddx10
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr18_+_6765171 1.204 ENSMUST00000097680.5
Rab18
RAB18, member RAS oncogene family
chr1_-_134361933 1.182 ENSMUST00000049470.4
Tmem183a
transmembrane protein 183A
chr1_+_58973521 1.176 ENSMUST00000114296.1
ENSMUST00000027185.4
Stradb

STE20-related kinase adaptor beta

chr4_+_131843459 1.173 ENSMUST00000030742.4
ENSMUST00000137321.1
Mecr

mitochondrial trans-2-enoyl-CoA reductase

chr13_+_98263187 1.170 ENSMUST00000091356.3
ENSMUST00000123924.1
Ankra2

ankyrin repeat, family A (RFXANK-like), 2

chr15_-_96460838 1.159 ENSMUST00000047835.6
Scaf11
SR-related CTD-associated factor 11
chr3_+_138143483 1.157 ENSMUST00000162864.1
Trmt10a
tRNA methyltransferase 10A
chr5_-_65335597 1.135 ENSMUST00000172660.1
ENSMUST00000172732.1
ENSMUST00000031092.8
Rfc1


replication factor C (activator 1) 1


chr1_-_37430071 1.134 ENSMUST00000027286.6
Coa5
cytochrome C oxidase assembly factor 5
chr1_-_150392719 1.129 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
BC003331


cDNA sequence BC003331


chr4_-_40279389 1.127 ENSMUST00000108108.2
ENSMUST00000095128.3
Ndufb6

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6

chr15_+_36174010 1.117 ENSMUST00000180159.1
ENSMUST00000057177.6
Polr2k

polymerase (RNA) II (DNA directed) polypeptide K

chr3_-_107696462 1.104 ENSMUST00000029490.8
Ahcyl1
S-adenosylhomocysteine hydrolase-like 1
chr12_+_8208107 1.094 ENSMUST00000037383.5
ENSMUST00000169104.1
1110057K04Rik

RIKEN cDNA 1110057K04 gene

chr5_+_67260794 1.088 ENSMUST00000161369.1
Tmem33
transmembrane protein 33
chrX_-_74023745 1.078 ENSMUST00000114353.3
ENSMUST00000101458.2
Irak1

interleukin-1 receptor-associated kinase 1

chr19_+_8735808 1.077 ENSMUST00000049424.9
Wdr74
WD repeat domain 74
chr10_+_94688739 1.071 ENSMUST00000020212.4
Ccdc41
coiled-coil domain containing 41
chr13_-_96542479 1.069 ENSMUST00000022172.4
Polk
polymerase (DNA directed), kappa
chr14_+_54883377 1.068 ENSMUST00000022806.3
ENSMUST00000172844.1
ENSMUST00000133397.2
ENSMUST00000134077.1
Bcl2l2


Gm20521
BCL2-like 2


predicted gene 20521
chr17_+_46496753 1.062 ENSMUST00000046497.6
Dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr12_-_73286698 1.060 ENSMUST00000116420.2
Trmt5
TRM5 tRNA methyltransferase 5
chr16_+_43889936 1.047 ENSMUST00000151183.1
2610015P09Rik
RIKEN cDNA 2610015P09 gene
chr3_+_138143429 1.046 ENSMUST00000040321.6
Trmt10a
tRNA methyltransferase 10A
chr1_-_106796687 1.042 ENSMUST00000094646.5
Vps4b
vacuolar protein sorting 4b (yeast)
chr5_+_124439891 1.030 ENSMUST00000059580.4
Setd8
SET domain containing (lysine methyltransferase) 8
chr13_+_98263105 1.029 ENSMUST00000150916.1
Ankra2
ankyrin repeat, family A (RFXANK-like), 2
chr19_-_24961545 1.026 ENSMUST00000025815.8
Cbwd1
COBW domain containing 1
chr15_-_81399594 1.021 ENSMUST00000023039.8
St13
suppression of tumorigenicity 13
chr4_+_115737738 1.014 ENSMUST00000106525.2
Efcab14
EF-hand calcium binding domain 14
chr4_-_147904680 1.007 ENSMUST00000105716.2
ENSMUST00000105715.1
ENSMUST00000105714.1
ENSMUST00000030884.3
Mfn2



mitofusin 2



chr4_-_19708922 1.006 ENSMUST00000108246.2
Wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr4_-_14826582 1.004 ENSMUST00000117268.1
Otud6b
OTU domain containing 6B
chr9_-_122950922 1.000 ENSMUST00000118422.1
1110059G10Rik
RIKEN cDNA 1110059G10 gene
chr4_+_115737754 0.998 ENSMUST00000106522.2
Efcab14
EF-hand calcium binding domain 14
chr15_-_94589870 0.991 ENSMUST00000023087.6
ENSMUST00000152590.1
Twf1

twinfilin, actin-binding protein, homolog 1 (Drosophila)

chr3_-_127553233 0.977 ENSMUST00000029588.5
Larp7
La ribonucleoprotein domain family, member 7
chr16_-_97922582 0.975 ENSMUST00000170757.1
C2cd2
C2 calcium-dependent domain containing 2
chr1_-_150393024 0.975 ENSMUST00000097546.2
ENSMUST00000111913.2
BC003331

cDNA sequence BC003331

chr11_+_59202480 0.954 ENSMUST00000108786.1
ENSMUST00000108787.2
ENSMUST00000045697.5
ENSMUST00000108785.1
ENSMUST00000108784.3
Mrpl55




mitochondrial ribosomal protein L55




chr9_-_122950960 0.943 ENSMUST00000035154.3
1110059G10Rik
RIKEN cDNA 1110059G10 gene
chr13_-_58402533 0.939 ENSMUST00000176207.1
Hnrnpk
heterogeneous nuclear ribonucleoprotein K
chr7_-_110844350 0.924 ENSMUST00000177462.1
ENSMUST00000176746.1
ENSMUST00000177236.1
Rnf141


ring finger protein 141


chr12_-_56345862 0.923 ENSMUST00000021416.7
Mbip
MAP3K12 binding inhibitory protein 1
chr9_+_121710389 0.907 ENSMUST00000035113.9
Deb1
differentially expressed in B16F10 1
chr13_+_96542602 0.904 ENSMUST00000179226.1
Col4a3bp
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr10_+_82954344 0.904 ENSMUST00000095396.3
Gm4799
predicted gene 4799
chr11_-_115276973 0.901 ENSMUST00000021078.2
Fdxr
ferredoxin reductase
chr14_+_55745678 0.900 ENSMUST00000019441.8
Nop9
NOP9 nucleolar protein
chr5_+_24100578 0.899 ENSMUST00000030841.5
ENSMUST00000163409.1
Klhl7

kelch-like 7

chr5_+_38039224 0.899 ENSMUST00000031008.6
ENSMUST00000042146.8
ENSMUST00000154929.1
Stx18


syntaxin 18


chr1_+_53313622 0.886 ENSMUST00000027265.3
Osgepl1
O-sialoglycoprotein endopeptidase-like 1
chr5_-_74531619 0.879 ENSMUST00000113542.2
ENSMUST00000072857.6
ENSMUST00000121330.1
ENSMUST00000151474.1
Scfd2



Sec1 family domain containing 2



chr15_+_65787023 0.878 ENSMUST00000015146.9
ENSMUST00000173858.1
ENSMUST00000172756.1
ENSMUST00000174856.1
Efr3a



EFR3 homolog A (S. cerevisiae)



chr5_-_65335564 0.874 ENSMUST00000172780.1
Rfc1
replication factor C (activator 1) 1
chr16_+_22009471 0.873 ENSMUST00000023561.7
Senp2
SUMO/sentrin specific peptidase 2
chr10_-_30618337 0.872 ENSMUST00000019925.5
Hint3
histidine triad nucleotide binding protein 3
chr7_-_55962424 0.870 ENSMUST00000126604.1
ENSMUST00000117812.1
ENSMUST00000119201.1
Nipa2


non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)


chr1_-_106796609 0.850 ENSMUST00000112736.1
Vps4b
vacuolar protein sorting 4b (yeast)
chr7_-_55962466 0.849 ENSMUST00000032635.7
ENSMUST00000152649.1
Nipa2

non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)

chr17_-_27907706 0.848 ENSMUST00000025057.4
Taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr9_+_123113215 0.848 ENSMUST00000026891.4
Exosc7
exosome component 7
chr14_-_76110760 0.845 ENSMUST00000022585.3
Gpalpp1
GPALPP motifs containing 1
chr15_-_81400043 0.840 ENSMUST00000172107.1
ENSMUST00000169204.1
ENSMUST00000163382.1
St13


suppression of tumorigenicity 13


chr10_-_30618436 0.840 ENSMUST00000161074.1
Hint3
histidine triad nucleotide binding protein 3
chr5_+_48372363 0.837 ENSMUST00000030968.2
Pacrgl
PARK2 co-regulated-like
chr18_-_35498856 0.829 ENSMUST00000025215.8
Sil1
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr10_-_82764088 0.829 ENSMUST00000130911.1
Nfyb
nuclear transcription factor-Y beta
chr17_+_25184561 0.828 ENSMUST00000088307.3
BC003965
cDNA sequence BC003965
chr3_-_100685431 0.826 ENSMUST00000008907.7
Man1a2
mannosidase, alpha, class 1A, member 2
chr6_+_57703051 0.825 ENSMUST00000151042.1
Lancl2
LanC (bacterial lantibiotic synthetase component C)-like 2
chr19_+_5041337 0.823 ENSMUST00000116567.2
Brms1
breast cancer metastasis-suppressor 1
chr5_+_35583018 0.818 ENSMUST00000068947.7
ENSMUST00000114237.1
ENSMUST00000156125.1
ENSMUST00000068563.5
Acox3



acyl-Coenzyme A oxidase 3, pristanoyl



chr1_+_53313636 0.814 ENSMUST00000114484.1
Osgepl1
O-sialoglycoprotein endopeptidase-like 1
chr5_-_36748639 0.810 ENSMUST00000071949.3
Bloc1s4
biogenesis of organelles complex-1, subunit 4, cappuccino
chr2_-_34826187 0.809 ENSMUST00000113075.1
ENSMUST00000113080.2
ENSMUST00000091020.3
Fbxw2


F-box and WD-40 domain protein 2


chr6_+_114643106 0.804 ENSMUST00000169310.3
ENSMUST00000182169.1
ENSMUST00000183165.1
ENSMUST00000182098.1
ENSMUST00000182793.1
ENSMUST00000182902.1
ENSMUST00000182428.1
ENSMUST00000182035.1
Atg7







autophagy related 7







chr5_+_67260696 0.800 ENSMUST00000161233.1
ENSMUST00000160352.1
Tmem33

transmembrane protein 33

chrX_-_74023908 0.797 ENSMUST00000033769.8
ENSMUST00000114352.1
ENSMUST00000068286.5
ENSMUST00000114360.3
ENSMUST00000114354.3
Irak1




interleukin-1 receptor-associated kinase 1




chr4_+_59003121 0.796 ENSMUST00000095070.3
ENSMUST00000174664.1
Dnajc25
Gm20503
DnaJ (Hsp40) homolog, subfamily C, member 25
predicted gene 20503
chr9_+_64179289 0.794 ENSMUST00000034965.6
Snapc5
small nuclear RNA activating complex, polypeptide 5
chrX_-_20962005 0.786 ENSMUST00000123836.1
Uxt
ubiquitously expressed transcript
chr12_-_98901478 0.784 ENSMUST00000065716.6
Eml5
echinoderm microtubule associated protein like 5
chr5_-_76905463 0.783 ENSMUST00000146570.1
ENSMUST00000142450.1
ENSMUST00000120963.1
Aasdh


aminoadipate-semialdehyde dehydrogenase


chr3_+_138143846 0.783 ENSMUST00000159481.1
Trmt10a
tRNA methyltransferase 10A
chr6_-_86733268 0.782 ENSMUST00000001185.7
Gmcl1
germ cell-less homolog 1 (Drosophila)
chr10_-_127041513 0.780 ENSMUST00000116231.2
Mettl21b
methyltransferase like 21B
chr5_+_124579134 0.772 ENSMUST00000031333.3
Gtf2h3
general transcription factor IIH, polypeptide 3
chr10_+_127041931 0.767 ENSMUST00000006915.7
ENSMUST00000120542.1
Mettl1

methyltransferase like 1

chr2_+_112454997 0.767 ENSMUST00000069747.5
Emc7
ER membrane protein complex subunit 7
chr2_-_34826071 0.761 ENSMUST00000113077.1
ENSMUST00000028220.3
Fbxw2

F-box and WD-40 domain protein 2

chr5_+_115341225 0.754 ENSMUST00000031508.4
Triap1
TP53 regulated inhibitor of apoptosis 1
chr10_-_81545175 0.741 ENSMUST00000043604.5
Gna11
guanine nucleotide binding protein, alpha 11
chr2_+_144556306 0.740 ENSMUST00000155876.1
ENSMUST00000149697.1
Sec23b

SEC23B (S. cerevisiae)

chr13_-_58402449 0.734 ENSMUST00000177019.1
Hnrnpk
heterogeneous nuclear ribonucleoprotein K
chr2_+_76675265 0.727 ENSMUST00000111920.1
Plekha3
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 3
chr9_+_50768228 0.725 ENSMUST00000042391.6
Fdxacb1
ferredoxin-fold anticodon binding domain containing 1
chr4_+_126677630 0.719 ENSMUST00000030642.2
Psmb2
proteasome (prosome, macropain) subunit, beta type 2
chr4_-_147904643 0.717 ENSMUST00000150881.1
Mfn2
mitofusin 2
chr11_+_83302641 0.716 ENSMUST00000176430.1
ENSMUST00000065692.7
Ap2b1

adaptor-related protein complex 2, beta 1 subunit

chr11_+_93996082 0.712 ENSMUST00000041956.7
Spag9
sperm associated antigen 9
chr7_+_16119868 0.706 ENSMUST00000006178.4
Kptn
kaptin
chr16_+_32247221 0.702 ENSMUST00000178573.1
ENSMUST00000023474.3
Wdr53

WD repeat domain 53

chr10_+_36974536 0.700 ENSMUST00000019911.7
Hdac2
histone deacetylase 2
chr16_-_18248697 0.699 ENSMUST00000115645.3
Ranbp1
RAN binding protein 1
chr8_+_34154563 0.697 ENSMUST00000033933.5
Tmem66
transmembrane protein 66
chr13_-_58215615 0.693 ENSMUST00000058735.5
ENSMUST00000076454.6
Ubqln1

ubiquilin 1

chr4_+_98923845 0.689 ENSMUST00000091358.4
Usp1
ubiquitin specific peptidase 1
chr17_+_46646225 0.688 ENSMUST00000002844.7
ENSMUST00000113429.1
ENSMUST00000113430.1
Mrpl2


mitochondrial ribosomal protein L2


chr5_-_24577467 0.684 ENSMUST00000030795.8
Abcf2
ATP-binding cassette, sub-family F (GCN20), member 2
chr9_-_50768109 0.673 ENSMUST00000177546.1
ENSMUST00000176238.1
1110032A03Rik

RIKEN cDNA 1110032A03 gene

chr19_+_3282901 0.672 ENSMUST00000025745.3
ENSMUST00000025743.6
Mrpl21

mitochondrial ribosomal protein L21

chr13_+_73604002 0.669 ENSMUST00000022102.7
Clptm1l
CLPTM1-like
chr1_-_59120079 0.667 ENSMUST00000094917.3
Tmem237
transmembrane protein 237
chr1_-_59119748 0.664 ENSMUST00000087475.4
Tmem237
transmembrane protein 237
chr7_+_138846579 0.658 ENSMUST00000155672.1
Ppp2r2d
protein phosphatase 2, regulatory subunit B, delta isoform
chr17_+_14978864 0.655 ENSMUST00000061688.9
9030025P20Rik
RIKEN cDNA 9030025P20 gene
chr10_+_58446845 0.654 ENSMUST00000003310.5
Ranbp2
RAN binding protein 2
chrX_+_57053549 0.648 ENSMUST00000114751.2
ENSMUST00000088652.5
Htatsf1

HIV TAT specific factor 1

chr3_+_138143888 0.633 ENSMUST00000161141.1
Trmt10a
tRNA methyltransferase 10A
chr11_+_60417238 0.631 ENSMUST00000070681.6
Gid4
GID complex subunit 4, VID24 homolog (S. cerevisiae)
chr2_-_103761178 0.628 ENSMUST00000028608.6
Nat10
N-acetyltransferase 10
chr9_-_44965519 0.625 ENSMUST00000125642.1
ENSMUST00000117506.1
ENSMUST00000117549.1
Ube4a


ubiquitination factor E4A, UFD2 homolog (S. cerevisiae)


chr11_-_98587193 0.623 ENSMUST00000052919.7
Ormdl3
ORM1-like 3 (S. cerevisiae)
chr3_+_103058302 0.611 ENSMUST00000029445.6
Nras
neuroblastoma ras oncogene
chr7_-_35056467 0.610 ENSMUST00000130491.1
Cebpg
CCAAT/enhancer binding protein (C/EBP), gamma
chr5_-_124579045 0.604 ENSMUST00000135361.1
ENSMUST00000031334.8
Eif2b1

eukaryotic translation initiation factor 2B, subunit 1 (alpha)

chr10_+_80141457 0.592 ENSMUST00000105367.1
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr7_+_132931142 0.591 ENSMUST00000106157.1
Zranb1
zinc finger, RAN-binding domain containing 1
chr4_+_98923810 0.584 ENSMUST00000030289.2
Usp1
ubiquitin specific peptidase 1
chr5_-_115341142 0.573 ENSMUST00000139167.1
Gatc
glutamyl-tRNA(Gln) amidotransferase, subunit C homolog (bacterial)
chr16_-_4077778 0.571 ENSMUST00000006137.8
Trap1
TNF receptor-associated protein 1
chr8_+_117157972 0.566 ENSMUST00000064488.4
ENSMUST00000162997.1
Gan

giant axonal neuropathy

chr16_+_14705832 0.565 ENSMUST00000023356.6
Snai2
snail homolog 2 (Drosophila)
chr11_+_70700473 0.562 ENSMUST00000152618.2
ENSMUST00000102554.1
ENSMUST00000094499.4
ENSMUST00000072187.5
Kif1c



kinesin family member 1C



chr11_+_96034885 0.551 ENSMUST00000006217.3
ENSMUST00000107700.3
Snf8

SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)

chr11_-_76243687 0.550 ENSMUST00000017430.5
Glod4
glyoxalase domain containing 4
chr5_+_29735940 0.550 ENSMUST00000114839.1
Dnajb6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr13_-_58402476 0.545 ENSMUST00000175847.1
ENSMUST00000043269.7
ENSMUST00000177060.1
Hnrnpk


heterogeneous nuclear ribonucleoprotein K


chr2_+_152226839 0.544 ENSMUST00000099224.3
ENSMUST00000124791.1
ENSMUST00000133119.1
Csnk2a1


casein kinase 2, alpha 1 polypeptide


chr17_-_27820445 0.543 ENSMUST00000114859.1
D17Wsu92e
DNA segment, Chr 17, Wayne State University 92, expressed
chrX_-_36864238 0.540 ENSMUST00000115249.3
ENSMUST00000115248.3
C330007P06Rik

RIKEN cDNA C330007P06 gene

chr19_-_6057736 0.537 ENSMUST00000007482.6
Mrpl49
mitochondrial ribosomal protein L49
chr6_+_114643094 0.526 ENSMUST00000032457.10
Atg7
autophagy related 7
chr8_+_27023793 0.526 ENSMUST00000033873.7
Erlin2
ER lipid raft associated 2
chr3_+_36552600 0.522 ENSMUST00000029269.5
ENSMUST00000136890.1
Exosc9

exosome component 9

chr4_+_107879745 0.521 ENSMUST00000030348.5
Magoh
mago-nashi homolog, proliferation-associated (Drosophila)
chr12_+_52097737 0.520 ENSMUST00000040090.9
Nubpl
nucleotide binding protein-like
chr18_-_68300194 0.512 ENSMUST00000152193.1
Fam210a
family with sequence similarity 210, member A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.7 2.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.6 1.9 GO:1903722 regulation of centriole elongation(GO:1903722)
0.6 1.8 GO:1904809 dense core granule localization(GO:0032253) dense core granule transport(GO:1901950) regulation of dense core granule transport(GO:1904809) positive regulation of dense core granule transport(GO:1904811)
0.6 1.7 GO:0061144 alveolar secondary septum development(GO:0061144)
0.6 2.2 GO:0035973 aggrephagy(GO:0035973)
0.5 5.1 GO:0055091 phospholipid homeostasis(GO:0055091) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.5 1.5 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.5 2.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.5 1.9 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.5 5.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.5 2.3 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.5 1.4 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.4 1.3 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157) nucleus disassembly(GO:1905690)
0.4 1.3 GO:0021759 globus pallidus development(GO:0021759)
0.4 1.7 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.4 1.1 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.3 1.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.3 1.3 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.3 1.0 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.3 2.9 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.3 1.3 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.3 0.3 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.3 1.6 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.3 1.2 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.3 0.9 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.3 1.2 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.3 1.9 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.3 1.1 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.2 1.5 GO:0060702 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.2 1.7 GO:0061734 parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization(GO:0061734)
0.2 0.7 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.2 1.9 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.2 0.9 GO:0032324 molybdopterin cofactor biosynthetic process(GO:0032324)
0.2 4.0 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2 2.5 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.2 0.6 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.2 0.6 GO:0106004 tRNA (guanine-N7)-methylation(GO:0106004)
0.2 2.8 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.2 3.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.2 0.6 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.2 0.6 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.2 2.6 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 0.7 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 1.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.2 3.7 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.2 0.3 GO:0006272 leading strand elongation(GO:0006272)
0.2 0.5 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.2 0.7 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.2 0.8 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.2 1.8 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.2 0.5 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 1.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.2 1.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2 1.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.4 GO:2001228 regulation of response to gamma radiation(GO:2001228)
0.1 1.3 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.8 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 1.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.8 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.8 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.4 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.1 0.5 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 0.4 GO:0009153 purine deoxyribonucleotide biosynthetic process(GO:0009153)
0.1 0.7 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 1.4 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 0.7 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 1.3 GO:0007270 neuron-neuron synaptic transmission(GO:0007270)
0.1 0.4 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.1 3.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 1.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.3 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.1 1.4 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.4 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 1.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.4 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 2.0 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 1.0 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 1.1 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.6 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.1 0.7 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.5 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 1.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.9 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.1 3.8 GO:0043039 tRNA aminoacylation(GO:0043039)
0.1 0.4 GO:0051661 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.1 0.3 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.8 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.1 0.5 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.9 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.6 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.3 GO:0051309 female meiosis chromosome separation(GO:0051309)
0.1 0.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.7 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 2.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.4 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.1 0.1 GO:0034982 mitochondrial protein processing(GO:0034982)
0.1 1.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.3 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.1 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.4 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415)
0.1 0.2 GO:0061792 secretory granule maturation(GO:0061792)
0.1 1.2 GO:0061462 protein localization to lysosome(GO:0061462)
0.1 0.4 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.5 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.8 GO:0006491 N-glycan processing(GO:0006491)
0.0 3.0 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.4 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.4 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145) positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.8 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 1.0 GO:0016556 mRNA modification(GO:0016556)
0.0 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.6 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.4 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.3 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442)
0.0 0.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 1.2 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.5 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.4 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.1 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.0 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.5 GO:0042026 protein refolding(GO:0042026)
0.0 1.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) regulation of mRNA polyadenylation(GO:1900363) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.3 GO:0008209 androgen metabolic process(GO:0008209)
0.0 0.1 GO:0010792 blastocyst hatching(GO:0001835) DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 1.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.4 GO:0006515 protein quality control by the ubiquitin-proteasome system(GO:0006515)
0.0 4.7 GO:0006839 mitochondrial transport(GO:0006839)
0.0 0.4 GO:0051452 intracellular pH reduction(GO:0051452)
0.0 0.8 GO:0097306 cellular response to alcohol(GO:0097306)
0.0 0.3 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.9 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.0 GO:0048320 axial mesoderm formation(GO:0048320)
0.0 0.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.6 3.6 GO:1990393 3M complex(GO:1990393)
0.5 1.5 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.5 2.0 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.5 2.7 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.5 3.2 GO:0097452 GAIT complex(GO:0097452)
0.3 1.7 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.3 2.0 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 0.7 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.2 2.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 0.8 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.2 3.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 0.6 GO:0000814 ESCRT II complex(GO:0000814)
0.2 2.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 0.7 GO:0140007 KICSTOR complex(GO:0140007)
0.2 1.7 GO:0005675 holo TFIIH complex(GO:0005675)
0.2 1.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 0.6 GO:0035339 SPOTS complex(GO:0035339)
0.1 7.8 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.9 GO:0090543 Flemming body(GO:0090543)
0.1 1.9 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 0.6 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 1.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.5 GO:0071144 activin responsive factor complex(GO:0032444) SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.8 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.5 GO:0043202 lysosomal lumen(GO:0043202)
0.1 1.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.4 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 1.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.4 GO:0030689 Noc complex(GO:0030689)
0.1 0.4 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.6 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 2.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 1.0 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 2.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.4 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.1 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 3.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.3 GO:0000242 pericentriolar material(GO:0000242)
0.1 1.7 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1 1.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.4 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.4 GO:0033263 CORVET complex(GO:0033263)
0.1 9.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 0.9 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.8 GO:0070822 Sin3-type complex(GO:0070822)
0.0 2.0 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 1.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.7 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.5 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.9 GO:0031201 SNARE complex(GO:0031201)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 4.1 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.5 GO:0071162 nuclear replication fork(GO:0043596) CMG complex(GO:0071162)
0.0 5.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.1 GO:0005811 lipid droplet(GO:0005811)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834) GTPase complex(GO:1905360)
0.0 1.9 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0035620 ceramide transporter activity(GO:0035620)
0.6 1.7 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.5 4.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.4 1.6 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.4 1.2 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.4 2.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.3 1.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.3 2.5 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.3 1.2 GO:0035851 histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851)
0.3 0.9 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3 0.8 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 1.5 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.2 0.7 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 2.0 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.2 0.9 GO:0030366 molybdopterin synthase activity(GO:0030366) molybdopterin adenylyltransferase activity(GO:0061598)
0.2 1.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 1.9 GO:0032564 dATP binding(GO:0032564)
0.2 0.6 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.2 3.0 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 2.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 5.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 1.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 3.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.2 1.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.4 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 0.7 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.8 GO:0004043 L-aminoadipate-semialdehyde dehydrogenase activity(GO:0004043)
0.1 2.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 3.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.3 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.5 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (adenine) methyltransferase activity(GO:0016433)
0.1 0.5 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 2.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 2.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 1.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.3 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 0.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 5.5 GO:0008374 O-acyltransferase activity(GO:0008374)
0.1 3.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 1.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.3 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.8 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.5 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.8 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 0.5 GO:0019779 Atg8 activating enzyme activity(GO:0019779)
0.1 0.8 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.4 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 0.4 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 1.1 GO:0051400 BH domain binding(GO:0051400)
0.1 5.7 GO:0051082 unfolded protein binding(GO:0051082)
0.1 0.7 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 2.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 0.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.5 GO:0000182 rDNA binding(GO:0000182)
0.0 1.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.9 GO:0070402 NADPH binding(GO:0070402)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 1.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.7 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 1.0 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 3.0 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 1.9 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.7 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.3 GO:0043495 protein membrane anchor(GO:0043495)
0.0 0.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.2 GO:0000049 tRNA binding(GO:0000049)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.8 GO:0030276 clathrin binding(GO:0030276)
0.0 1.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding(GO:0070530)
0.0 2.5 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 3.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 1.0 GO:0097110 scaffold protein binding(GO:0097110)
0.0 2.7 GO:0061660 Atg12 activating enzyme activity(GO:0019778) Atg8-specific protease activity(GO:0019786) Atg12 conjugating enzyme activity(GO:0061651) Atg12 ligase activity(GO:0061660)
0.0 0.4 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 1.1 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 1.3 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.4 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 0.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 7.7 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 2.2 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.1 1.0 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.9 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 3.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 2.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.9 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.8 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 4.2 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.4 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.0 0.5 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 1.2 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.9 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.5 PID_GLYPICAN_1PATHWAY Glypican 1 network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.1 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 2.6 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 2.6 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 1.9 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.4 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.5 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 3.6 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 3.2 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 7.4 REACTOME_TRIGLYCERIDE_BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.1 2.6 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 0.8 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.6 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 0.3 REACTOME_MRNA_CAPPING Genes involved in mRNA Capping
0.1 1.5 REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.1 0.7 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.6 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.9 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.6 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 2.0 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.6 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.6 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.8 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.8 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.8 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 2.5 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 0.5 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.3 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 4.8 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.0 1.6 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production