Motif ID: Creb3

Z-value: 1.349


Transcription factors associated with Creb3:

Gene SymbolEntrez IDGene Name
Creb3 ENSMUSG00000028466.9 Creb3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb3mm10_v2_chr4_+_43562672_435629470.173.4e-01Click!


Activity profile for motif Creb3.

activity profile for motif Creb3


Sorted Z-values histogram for motif Creb3

Sorted Z-values for motif Creb3



Network of associatons between targets according to the STRING database.



First level regulatory network of Creb3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_123267445 7.667 ENSMUST00000047923.7
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr17_+_35439155 7.243 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
H2-Q7



histocompatibility 2, Q region locus 7



chr1_+_58113136 6.784 ENSMUST00000040999.7
Aox3
aldehyde oxidase 3
chr16_+_13903152 5.399 ENSMUST00000128757.1
Mpv17l
Mpv17 transgene, kidney disease mutant-like
chr4_-_105109829 5.195 ENSMUST00000030243.7
Prkaa2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr8_+_107150621 5.116 ENSMUST00000034400.3
Cyb5b
cytochrome b5 type B
chr9_+_44379490 5.071 ENSMUST00000066601.6
Hyou1
hypoxia up-regulated 1
chr14_-_59597836 4.871 ENSMUST00000167100.1
ENSMUST00000022555.4
ENSMUST00000056997.7
ENSMUST00000171683.1
Cdadc1



cytidine and dCMP deaminase domain containing 1



chr2_+_67748212 4.766 ENSMUST00000180887.1
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr9_+_44379536 4.690 ENSMUST00000161318.1
ENSMUST00000160902.1
Hyou1

hypoxia up-regulated 1

chr9_-_45009590 4.666 ENSMUST00000102832.1
Cd3e
CD3 antigen, epsilon polypeptide
chr2_+_105224314 4.627 ENSMUST00000068813.2
0610012H03Rik
RIKEN cDNA 0610012H03 gene
chr10_-_24101951 4.188 ENSMUST00000170267.1
Taar8c
trace amine-associated receptor 8C
chr17_-_26508463 4.099 ENSMUST00000025025.6
Dusp1
dual specificity phosphatase 1
chr3_+_122895072 4.078 ENSMUST00000023820.5
Fabp2
fatty acid binding protein 2, intestinal
chr2_+_72054598 4.012 ENSMUST00000028525.5
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr3_+_89459325 3.755 ENSMUST00000107410.1
Pmvk
phosphomevalonate kinase
chr17_-_57228003 3.727 ENSMUST00000177046.1
ENSMUST00000024988.8
C3

complement component 3

chr4_-_118544010 3.576 ENSMUST00000128098.1
Tmem125
transmembrane protein 125
chr10_-_4432312 3.452 ENSMUST00000126102.1
ENSMUST00000131853.1
ENSMUST00000042251.4
Rmnd1


required for meiotic nuclear division 1 homolog (S. cerevisiae)


chr10_+_41519493 3.432 ENSMUST00000019962.8
Cd164
CD164 antigen
chr2_+_155276297 3.405 ENSMUST00000029128.3
Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
chr8_-_106136890 3.286 ENSMUST00000115979.2
Esrp2
epithelial splicing regulatory protein 2
chr2_-_168742100 3.265 ENSMUST00000109177.1
Atp9a
ATPase, class II, type 9A
chr1_-_183369529 3.185 ENSMUST00000069922.5
Mia3
melanoma inhibitory activity 3
chr8_-_106136792 3.169 ENSMUST00000146940.1
Esrp2
epithelial splicing regulatory protein 2
chr5_+_28071356 3.101 ENSMUST00000059155.10
Insig1
insulin induced gene 1
chr2_+_173153048 3.073 ENSMUST00000029017.5
Pck1
phosphoenolpyruvate carboxykinase 1, cytosolic
chr7_+_27195781 2.970 ENSMUST00000108379.1
ENSMUST00000179391.1
BC024978

cDNA sequence BC024978

chrX_+_73787062 2.965 ENSMUST00000002090.2
Ssr4
signal sequence receptor, delta
chrX_+_73787002 2.921 ENSMUST00000166518.1
Ssr4
signal sequence receptor, delta
chr7_-_126898249 2.912 ENSMUST00000121532.1
ENSMUST00000032926.5
Tmem219

transmembrane protein 219

chr9_+_104063376 2.912 ENSMUST00000120854.1
Acad11
acyl-Coenzyme A dehydrogenase family, member 11
chr11_-_72796028 2.896 ENSMUST00000156294.1
Cyb5d2
cytochrome b5 domain containing 2
chr10_-_4432285 2.838 ENSMUST00000155172.1
Rmnd1
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr11_-_72795801 2.818 ENSMUST00000079681.5
Cyb5d2
cytochrome b5 domain containing 2
chr5_+_125389284 2.813 ENSMUST00000100700.2
Gm10382
predicted gene 10382
chr11_+_52232183 2.716 ENSMUST00000109072.1
Skp1a
S-phase kinase-associated protein 1A
chr19_-_10101501 2.664 ENSMUST00000025567.7
Fads2
fatty acid desaturase 2
chr7_+_128523576 2.544 ENSMUST00000033136.7
Bag3
BCL2-associated athanogene 3
chr10_-_81407641 2.518 ENSMUST00000140916.1
Nfic
nuclear factor I/C
chr13_-_37994111 2.500 ENSMUST00000021864.6
Ssr1
signal sequence receptor, alpha
chr7_-_44496406 2.431 ENSMUST00000118515.1
ENSMUST00000138328.1
ENSMUST00000008284.8
ENSMUST00000118808.1
Emc10



ER membrane protein complex subunit 10



chr3_+_155093414 2.377 ENSMUST00000029833.7
Lrriq3
leucine-rich repeats and IQ motif containing 3
chr5_+_107331157 2.311 ENSMUST00000031215.8
ENSMUST00000112677.3
Brdt

bromodomain, testis-specific

chr10_-_67285180 2.293 ENSMUST00000159002.1
ENSMUST00000077839.6
Nrbf2

nuclear receptor binding factor 2

chr11_+_52232009 2.285 ENSMUST00000037324.5
ENSMUST00000166537.1
Skp1a

S-phase kinase-associated protein 1A

chr3_+_89459118 2.223 ENSMUST00000029564.5
Pmvk
phosphomevalonate kinase
chrX_-_136741155 2.218 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
Morf4l2




mortality factor 4 like 2




chr15_-_3995708 2.216 ENSMUST00000046633.8
AW549877
expressed sequence AW549877
chrX_-_60893430 2.197 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr2_-_148040196 2.154 ENSMUST00000136555.1
9030622O22Rik
RIKEN cDNA 9030622O22 gene
chr19_-_6909599 2.150 ENSMUST00000173091.1
Prdx5
peroxiredoxin 5
chr1_+_131019843 2.126 ENSMUST00000016673.5
Il10
interleukin 10
chr3_+_88206786 2.109 ENSMUST00000181134.1
ENSMUST00000181550.1
Gm3764

predicted gene 3764

chr11_-_69920581 2.077 ENSMUST00000108610.1
Eif5a
eukaryotic translation initiation factor 5A
chr4_+_153957230 2.053 ENSMUST00000058393.2
ENSMUST00000105645.2
A430005L14Rik

RIKEN cDNA A430005L14 gene

chr14_-_55643523 2.053 ENSMUST00000132338.1
Tm9sf1
transmembrane 9 superfamily member 1
chr1_+_157506728 2.053 ENSMUST00000086130.2
Sec16b
SEC16 homolog B (S. cerevisiae)
chr1_+_157506777 2.047 ENSMUST00000027881.8
Sec16b
SEC16 homolog B (S. cerevisiae)
chr5_+_91139591 2.017 ENSMUST00000031325.4
Areg
amphiregulin
chr14_-_55643800 1.987 ENSMUST00000122358.1
Tm9sf1
transmembrane 9 superfamily member 1
chr17_-_90088343 1.967 ENSMUST00000173917.1
Nrxn1
neurexin I
chr4_+_153957247 1.966 ENSMUST00000141493.1
A430005L14Rik
RIKEN cDNA A430005L14 gene
chr9_-_104063049 1.957 ENSMUST00000035166.5
Uba5
ubiquitin-like modifier activating enzyme 5
chr6_-_119848120 1.953 ENSMUST00000183703.1
ENSMUST00000183911.1
Erc1

ELKS/RAB6-interacting/CAST family member 1

chr10_+_128322443 1.952 ENSMUST00000026446.2
Cnpy2
canopy 2 homolog (zebrafish)
chr7_-_45459839 1.949 ENSMUST00000094434.4
Ftl1
ferritin light chain 1
chr8_+_108714644 1.938 ENSMUST00000043896.8
Zfhx3
zinc finger homeobox 3
chr8_-_34146974 1.916 ENSMUST00000033910.8
Leprotl1
leptin receptor overlapping transcript-like 1
chr6_+_48593883 1.915 ENSMUST00000154010.1
ENSMUST00000163452.1
ENSMUST00000118229.1
ENSMUST00000009420.8
Repin1



replication initiator 1



chr6_+_88084473 1.911 ENSMUST00000032143.6
Rpn1
ribophorin I
chr11_-_86807624 1.883 ENSMUST00000018569.7
Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr6_-_119848059 1.860 ENSMUST00000184864.1
Erc1
ELKS/RAB6-interacting/CAST family member 1
chr11_-_88863717 1.845 ENSMUST00000107904.2
Akap1
A kinase (PRKA) anchor protein 1
chr9_+_67759423 1.817 ENSMUST00000171652.1
C2cd4b
C2 calcium-dependent domain containing 4B
chr14_-_55643720 1.813 ENSMUST00000138085.1
Tm9sf1
transmembrane 9 superfamily member 1
chr17_-_34214459 1.795 ENSMUST00000121995.1
Gm15821
predicted gene 15821
chr7_-_90475971 1.791 ENSMUST00000032843.7
Tmem126b
transmembrane protein 126B
chr7_+_44496588 1.785 ENSMUST00000107927.3
Fam71e1
family with sequence similarity 71, member E1
chr17_+_46383725 1.775 ENSMUST00000113481.1
ENSMUST00000138127.1
Zfp318

zinc finger protein 318

chr1_+_171345684 1.774 ENSMUST00000006579.4
Pfdn2
prefoldin 2
chr11_+_94653767 1.773 ENSMUST00000025278.7
Mrpl27
mitochondrial ribosomal protein L27
chr2_+_162987502 1.766 ENSMUST00000117123.1
Sgk2
serum/glucocorticoid regulated kinase 2
chr7_-_133776681 1.761 ENSMUST00000130182.1
ENSMUST00000106139.1
Dhx32

DEAH (Asp-Glu-Ala-His) box polypeptide 32

chr3_+_30792876 1.759 ENSMUST00000029256.7
Sec62
SEC62 homolog (S. cerevisiae)
chr9_+_108339048 1.755 ENSMUST00000082429.5
Gpx1
glutathione peroxidase 1
chr19_-_6910088 1.741 ENSMUST00000025904.5
Prdx5
peroxiredoxin 5
chr9_+_44084944 1.741 ENSMUST00000176416.1
ENSMUST00000065461.7
Usp2

ubiquitin specific peptidase 2

chr17_-_56183887 1.739 ENSMUST00000019723.7
D17Wsu104e
DNA segment, Chr 17, Wayne State University 104, expressed
chr8_+_111033890 1.730 ENSMUST00000034441.7
Aars
alanyl-tRNA synthetase
chr12_+_51377560 1.723 ENSMUST00000021335.5
Scfd1
Sec1 family domain containing 1
chr15_+_99591028 1.689 ENSMUST00000169082.1
Aqp5
aquaporin 5
chr6_-_108185552 1.649 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
Sumf1


sulfatase modifying factor 1


chr7_+_102210335 1.637 ENSMUST00000140631.1
ENSMUST00000120879.1
ENSMUST00000146996.1
Pgap2


post-GPI attachment to proteins 2


chr2_+_155382186 1.631 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr6_-_71144338 1.630 ENSMUST00000074241.7
ENSMUST00000160918.1
Thnsl2

threonine synthase-like 2 (bacterial)

chr4_+_47474652 1.598 ENSMUST00000065678.5
ENSMUST00000137461.1
ENSMUST00000125622.1
Sec61b


Sec61 beta subunit


chr13_-_38528412 1.597 ENSMUST00000035988.8
Txndc5
thioredoxin domain containing 5
chr5_+_107403496 1.578 ENSMUST00000049146.5
Ephx4
epoxide hydrolase 4
chr5_+_124540695 1.553 ENSMUST00000060226.4
Tmed2
transmembrane emp24 domain trafficking protein 2
chr9_+_44101722 1.552 ENSMUST00000161703.1
ENSMUST00000161381.1
ENSMUST00000034654.7
Mfrp


membrane-type frizzled-related protein


chr3_-_155093346 1.548 ENSMUST00000066568.4
Fpgt
fucose-1-phosphate guanylyltransferase
chr7_-_144939823 1.548 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr4_+_3938888 1.543 ENSMUST00000121110.1
ENSMUST00000108386.1
ENSMUST00000149544.1
Chchd7


coiled-coil-helix-coiled-coil-helix domain containing 7


chr2_+_80315461 1.534 ENSMUST00000028392.7
Dnajc10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr5_+_113735782 1.520 ENSMUST00000065698.5
Ficd
FIC domain containing
chr4_+_108328136 1.508 ENSMUST00000131656.1
Selrc1
Sel1 repeat containing 1
chr17_+_6106880 1.492 ENSMUST00000149756.1
Tulp4
tubby like protein 4
chr12_-_59011996 1.483 ENSMUST00000021375.5
Sec23a
SEC23A (S. cerevisiae)
chr19_-_6057736 1.481 ENSMUST00000007482.6
Mrpl49
mitochondrial ribosomal protein L49
chr12_+_69184158 1.477 ENSMUST00000060579.8
Mgat2
mannoside acetylglucosaminyltransferase 2
chr13_-_100833369 1.476 ENSMUST00000067246.4
Slc30a5
solute carrier family 30 (zinc transporter), member 5
chr19_+_11965817 1.467 ENSMUST00000025590.9
Osbp
oxysterol binding protein
chr5_+_120431770 1.460 ENSMUST00000031591.7
Lhx5
LIM homeobox protein 5
chr10_-_115251407 1.449 ENSMUST00000020339.8
Tbc1d15
TBC1 domain family, member 15
chr19_+_8741669 1.439 ENSMUST00000176314.1
ENSMUST00000073430.7
ENSMUST00000175901.1
Stx5a


syntaxin 5A


chr7_+_127912510 1.423 ENSMUST00000033070.7
Kat8
K(lysine) acetyltransferase 8
chrX_-_155623325 1.408 ENSMUST00000038665.5
Ptchd1
patched domain containing 1
chrX_+_99821021 1.403 ENSMUST00000096363.2
Tmem28
transmembrane protein 28
chr3_+_89246397 1.394 ENSMUST00000168900.1
Krtcap2
keratinocyte associated protein 2
chr7_-_16874845 1.394 ENSMUST00000181501.1
9330104G04Rik
RIKEN cDNA 9330104G04 gene
chr6_-_119848093 1.392 ENSMUST00000079582.4
Erc1
ELKS/RAB6-interacting/CAST family member 1
chr4_+_33031371 1.384 ENSMUST00000124992.1
Ube2j1
ubiquitin-conjugating enzyme E2J 1
chr12_+_108792946 1.383 ENSMUST00000021692.7
Yy1
YY1 transcription factor
chr10_-_128923948 1.381 ENSMUST00000131271.1
Bloc1s1
biogenesis of lysosome-related organelles complex-1, subunit 1
chr4_-_150909812 1.375 ENSMUST00000134751.1
ENSMUST00000030805.7
Park7

Parkinson disease (autosomal recessive, early onset) 7

chr7_+_45873127 1.374 ENSMUST00000107718.1
Kdelr1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr7_-_118533298 1.366 ENSMUST00000098090.3
ENSMUST00000032887.3
Coq7

demethyl-Q 7

chr8_+_45975514 1.358 ENSMUST00000034051.6
Ufsp2
UFM1-specific peptidase 2
chr5_-_124352233 1.358 ENSMUST00000111472.1
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr14_+_26638237 1.346 ENSMUST00000112318.3
Arf4
ADP-ribosylation factor 4
chr9_+_59539643 1.343 ENSMUST00000026262.6
Hexa
hexosaminidase A
chr11_-_51756378 1.339 ENSMUST00000109092.1
ENSMUST00000064297.4
ENSMUST00000109097.2
Sec24a


Sec24 related gene family, member A (S. cerevisiae)


chr16_-_13903085 1.335 ENSMUST00000023361.5
ENSMUST00000115802.1
Pdxdc1

pyridoxal-dependent decarboxylase domain containing 1

chr4_+_59003121 1.331 ENSMUST00000095070.3
ENSMUST00000174664.1
Dnajc25
Gm20503
DnaJ (Hsp40) homolog, subfamily C, member 25
predicted gene 20503
chrX_-_163549677 1.330 ENSMUST00000033730.2
Grpr
gastrin releasing peptide receptor
chr14_+_69555377 1.330 ENSMUST00000185072.1
ENSMUST00000168356.1
ENSMUST00000064846.7
Gm21685


predicted gene, 21685


chr2_-_132247623 1.326 ENSMUST00000110164.1
Tmem230
transmembrane protein 230
chr11_+_82781108 1.308 ENSMUST00000092849.5
ENSMUST00000021039.5
ENSMUST00000080461.5
ENSMUST00000173347.1
ENSMUST00000173727.1
ENSMUST00000173009.1
ENSMUST00000131537.2
ENSMUST00000173722.1
Lig3







ligase III, DNA, ATP-dependent







chr14_-_55643251 1.286 ENSMUST00000120041.1
ENSMUST00000121937.1
ENSMUST00000133707.1
ENSMUST00000002391.8
ENSMUST00000121791.1
Tm9sf1




transmembrane 9 superfamily member 1




chr8_+_92961027 1.283 ENSMUST00000072939.6
Slc6a2
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
chr4_-_148038769 1.274 ENSMUST00000030879.5
ENSMUST00000137724.1
Clcn6

chloride channel 6

chr10_+_24076500 1.274 ENSMUST00000051133.5
Taar8a
trace amine-associated receptor 8A
chr10_-_128922888 1.269 ENSMUST00000135161.1
Rdh5
retinol dehydrogenase 5
chr2_-_132247747 1.258 ENSMUST00000110163.1
ENSMUST00000180286.1
ENSMUST00000028816.2
Tmem230


transmembrane protein 230


chr1_-_93445642 1.246 ENSMUST00000042498.7
Hdlbp
high density lipoprotein (HDL) binding protein
chr1_-_172082757 1.239 ENSMUST00000003550.4
Ncstn
nicastrin
chr18_-_35215008 1.219 ENSMUST00000091636.3
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr10_-_128923439 1.205 ENSMUST00000153731.1
ENSMUST00000026405.3
Bloc1s1

biogenesis of lysosome-related organelles complex-1, subunit 1

chr16_-_44139196 1.204 ENSMUST00000063661.6
ENSMUST00000114666.2
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr10_+_121365078 1.173 ENSMUST00000040344.6
Gns
glucosamine (N-acetyl)-6-sulfatase
chr5_-_31291026 1.163 ENSMUST00000041565.7
Ift172
intraflagellar transport 172
chr1_+_75168631 1.157 ENSMUST00000162768.1
ENSMUST00000160439.1
ENSMUST00000027394.5
Zfand2b


zinc finger, AN1 type domain 2B


chr19_+_8741473 1.156 ENSMUST00000177373.1
ENSMUST00000010254.9
Stx5a

syntaxin 5A

chr2_-_91070283 1.146 ENSMUST00000111436.2
ENSMUST00000073575.5
Slc39a13

solute carrier family 39 (metal ion transporter), member 13

chr2_+_70661556 1.125 ENSMUST00000112201.1
ENSMUST00000028509.4
ENSMUST00000133432.1
ENSMUST00000112205.1
Gorasp2



golgi reassembly stacking protein 2



chr19_+_8741413 1.124 ENSMUST00000176381.1
Stx5a
syntaxin 5A
chr16_+_36875119 1.121 ENSMUST00000135406.1
ENSMUST00000114812.1
ENSMUST00000134616.1
ENSMUST00000023534.6
Golgb1


Golgb1
golgi autoantigen, golgin subfamily b, macrogolgin 1


golgi autoantigen, golgin subfamily b, macrogolgin 1
chr1_-_13589717 1.120 ENSMUST00000027068.4
Tram1
translocating chain-associating membrane protein 1
chr13_-_55321928 1.119 ENSMUST00000035242.7
Rab24
RAB24, member RAS oncogene family
chr17_-_24163668 1.119 ENSMUST00000040735.5
Amdhd2
amidohydrolase domain containing 2
chr11_-_118415794 1.117 ENSMUST00000164927.1
Cant1
calcium activated nucleotidase 1
chr18_-_84685615 1.116 ENSMUST00000025546.9
Cndp2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr3_-_97767916 1.115 ENSMUST00000045243.8
Pde4dip
phosphodiesterase 4D interacting protein (myomegalin)
chrX_-_20291776 1.106 ENSMUST00000072451.4
Slc9a7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr6_-_134897815 1.104 ENSMUST00000165392.1
ENSMUST00000046255.7
ENSMUST00000111932.1
ENSMUST00000116515.2
Gpr19



G protein-coupled receptor 19



chr11_+_72796164 1.092 ENSMUST00000172220.1
Zzef1
zinc finger, ZZ-type with EF hand domain 1
chr10_+_79682169 1.074 ENSMUST00000020550.5
Cdc34
cell division cycle 34
chr16_-_13903051 1.072 ENSMUST00000115803.1
Pdxdc1
pyridoxal-dependent decarboxylase domain containing 1
chr6_-_101377342 1.063 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr11_+_72796254 1.061 ENSMUST00000069395.5
Zzef1
zinc finger, ZZ-type with EF hand domain 1
chr9_-_20976762 1.057 ENSMUST00000054197.5
S1pr2
sphingosine-1-phosphate receptor 2
chr12_-_4038905 1.056 ENSMUST00000111178.1
Efr3b
EFR3 homolog B (S. cerevisiae)
chr19_-_5802640 1.055 ENSMUST00000173523.1
ENSMUST00000173499.1
ENSMUST00000172812.2
Malat1


metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)


chr6_+_29348069 1.036 ENSMUST00000173216.1
ENSMUST00000031779.10
ENSMUST00000090481.7
Calu


calumenin


chr5_+_143403819 1.034 ENSMUST00000110731.2
Kdelr2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr16_-_13903015 1.031 ENSMUST00000115804.2
Pdxdc1
pyridoxal-dependent decarboxylase domain containing 1
chr17_-_47688028 1.029 ENSMUST00000113301.1
ENSMUST00000113302.3
Tomm6

translocase of outer mitochondrial membrane 6 homolog (yeast)

chr2_+_23156369 1.024 ENSMUST00000028117.3
Yme1l1
YME1-like 1 (S. cerevisiae)
chr15_-_99820072 1.016 ENSMUST00000109024.2
Lima1
LIM domain and actin binding 1
chr1_-_51478390 1.008 ENSMUST00000027279.5
Nabp1
nucleic acid binding protein 1
chr1_+_182124737 0.992 ENSMUST00000111018.1
ENSMUST00000027792.5
Srp9

signal recognition particle 9

chr13_+_55321991 0.979 ENSMUST00000021942.6
Prelid1
PRELI domain containing 1
chr1_+_75142775 0.978 ENSMUST00000097694.4
Fam134a
family with sequence similarity 134, member A
chr14_+_79587691 0.968 ENSMUST00000054908.8
Sugt1
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
chr5_-_143732273 0.968 ENSMUST00000053287.5
Usp42
ubiquitin specific peptidase 42
chr15_-_102136225 0.964 ENSMUST00000154032.1
Spryd3
SPRY domain containing 3
chr2_+_74762980 0.949 ENSMUST00000047793.4
Hoxd1
homeobox D1
chr14_-_31251194 0.935 ENSMUST00000022459.3
Phf7
PHD finger protein 7
chr5_+_30869623 0.929 ENSMUST00000114716.1
Tmem214
transmembrane protein 214
chr4_+_3938904 0.926 ENSMUST00000120732.1
ENSMUST00000041122.4
ENSMUST00000121651.1
ENSMUST00000121210.1
ENSMUST00000119307.1
ENSMUST00000123769.1
Chchd7





coiled-coil-helix-coiled-coil-helix domain containing 7





chr2_-_91070180 0.918 ENSMUST00000153367.1
ENSMUST00000079976.3
Slc39a13

solute carrier family 39 (metal ion transporter), member 13

chr5_+_30869579 0.917 ENSMUST00000046349.7
Tmem214
transmembrane protein 214
chr11_+_53350783 0.912 ENSMUST00000060945.5
Aff4
AF4/FMR2 family, member 4
chr10_+_77606571 0.911 ENSMUST00000099538.5
Sumo3
SMT3 suppressor of mif two 3 homolog 3 (yeast)
chr4_-_134000857 0.909 ENSMUST00000105887.1
ENSMUST00000012262.5
ENSMUST00000144668.1
ENSMUST00000105889.3
Dhdds



dehydrodolichyl diphosphate synthase



chr12_+_71309876 0.897 ENSMUST00000061273.5
ENSMUST00000150639.1
Dact1

dapper homolog 1, antagonist of beta-catenin (xenopus)

chr10_+_127041931 0.896 ENSMUST00000006915.7
ENSMUST00000120542.1
Mettl1

methyltransferase like 1

chr17_-_34121944 0.895 ENSMUST00000151986.1
Brd2
bromodomain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.8 GO:0036483 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
1.5 6.0 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
1.4 6.8 GO:0009115 xanthine catabolic process(GO:0009115)
1.3 3.9 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
1.2 17.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
1.0 3.1 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
1.0 4.0 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.9 4.7 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.9 5.4 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.7 3.7 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.7 2.1 GO:0060300 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) regulation of cytokine activity(GO:0060300) negative regulation of sensory perception of pain(GO:1904057)
0.6 1.9 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.6 3.6 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.6 1.7 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.5 4.8 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.5 2.0 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.5 2.0 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.5 1.9 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.5 6.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.5 4.7 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.5 1.4 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.5 1.4 GO:1903184 enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) protein deglycation(GO:0036525) peptidyl-cysteine deglycation(GO:0036526) peptidyl-arginine deglycation(GO:0036527) peptidyl-lysine deglycation(GO:0036528) protein deglycation, glyoxal removal(GO:0036529) glutathione deglycation(GO:0036531) glycolate biosynthetic process(GO:0046295) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.4 3.7 GO:0090166 Golgi disassembly(GO:0090166)
0.4 1.6 GO:0006566 threonine metabolic process(GO:0006566)
0.4 2.0 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.4 5.2 GO:0014850 response to muscle activity(GO:0014850)
0.4 4.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.3 2.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.3 1.4 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.3 1.3 GO:0036343 psychomotor behavior(GO:0036343)
0.3 1.3 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298)
0.3 2.0 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.3 1.0 GO:0052203 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.3 0.9 GO:0106004 tRNA (guanine-N7)-methylation(GO:0106004)
0.3 1.9 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.3 1.5 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.3 1.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.3 2.6 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.3 0.8 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.3 1.8 GO:0018158 protein oxidation(GO:0018158)
0.2 1.0 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.2 0.7 GO:0070625 zymogen granule exocytosis(GO:0070625)
0.2 1.8 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.2 2.7 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.2 1.1 GO:0035063 nuclear speck organization(GO:0035063)
0.2 0.4 GO:0070375 ERK5 cascade(GO:0070375)
0.2 8.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2 0.8 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2 1.7 GO:0015670 carbon dioxide transport(GO:0015670)
0.2 5.0 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.2 1.5 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.2 0.5 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.2 0.5 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 1.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.2 4.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.2 1.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262) glucosamine-containing compound catabolic process(GO:1901072)
0.2 6.5 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.2 1.1 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 7.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 1.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.8 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 2.1 GO:0061525 hindgut development(GO:0061525)
0.1 2.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 1.8 GO:0006620 posttranslational protein targeting to endoplasmic reticulum membrane(GO:0006620)
0.1 0.5 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.1 1.6 GO:0098719 sodium ion import across plasma membrane(GO:0098719)
0.1 1.5 GO:0006824 cobalt ion transport(GO:0006824)
0.1 1.4 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 2.6 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 1.6 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 2.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 2.3 GO:0007141 male meiosis I(GO:0007141)
0.1 4.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 4.1 GO:0050892 intestinal absorption(GO:0050892)
0.1 2.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 1.7 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 1.1 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.1 0.9 GO:0016093 polyprenol metabolic process(GO:0016093)
0.1 1.2 GO:0007220 Notch receptor processing(GO:0007220)
0.1 1.9 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.1 1.0 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 1.0 GO:0036296 cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296)
0.1 0.3 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 2.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 1.4 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cytosol(GO:1902656)
0.1 1.1 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.1 1.5 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.1 2.2 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.8 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 0.7 GO:0045794 negative regulation of cell volume(GO:0045794)
0.1 1.0 GO:0051382 kinetochore assembly(GO:0051382)
0.1 1.4 GO:0021794 thalamus development(GO:0021794)
0.1 0.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 1.6 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 1.3 GO:0015874 norepinephrine transport(GO:0015874)
0.1 0.5 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.7 GO:0034982 mitochondrial protein processing(GO:0034982)
0.1 1.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.6 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 1.6 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.8 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.4 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.1 1.4 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 3.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.9 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 1.4 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.6 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 1.4 GO:0002369 T cell cytokine production(GO:0002369)
0.0 2.3 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.9 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.0 0.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 1.0 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 1.6 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 1.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.3 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.6 GO:0097352 autophagosome maturation(GO:0097352)
0.0 1.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 1.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 2.5 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.5 GO:0060324 face development(GO:0060324)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 1.6 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 1.0 GO:0031529 ruffle organization(GO:0031529)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.7 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 2.5 GO:0048489 synaptic vesicle transport(GO:0048489) establishment of synaptic vesicle localization(GO:0097480) vesicle-mediated transport in synapse(GO:0099003)
0.0 0.7 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.1 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.0 0.3 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 1.8 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 1.3 GO:0006457 protein folding(GO:0006457)
0.0 1.1 GO:0007030 Golgi organization(GO:0007030)
0.0 2.9 GO:0006914 autophagy(GO:0006914) process utilizing autophagic mechanism(GO:0061919)
0.0 1.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.2 GO:0030203 glycosaminoglycan metabolic process(GO:0030203)
0.0 0.1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.8 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.2 GO:0008203 cholesterol metabolic process(GO:0008203)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 11.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.8 4.0 GO:0044316 cone cell pedicle(GO:0044316)
0.8 11.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.7 7.5 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.7 5.0 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.6 7.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.5 4.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.4 3.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.4 5.4 GO:0044754 autolysosome(GO:0044754)
0.4 2.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.4 2.6 GO:0099078 BORC complex(GO:0099078)
0.3 5.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.3 2.5 GO:0097413 Lewy body(GO:0097413)
0.3 1.2 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.3 1.4 GO:0072487 MSL complex(GO:0072487)
0.3 4.1 GO:0045179 apical cortex(GO:0045179)
0.2 1.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.2 3.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 1.0 GO:0070876 SOSS complex(GO:0070876)
0.2 2.1 GO:0005642 annulate lamellae(GO:0005642)
0.2 3.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 0.7 GO:0005745 m-AAA complex(GO:0005745)
0.2 0.9 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.2 1.8 GO:0016272 prefoldin complex(GO:0016272)
0.2 2.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 5.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 1.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 1.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 3.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.4 GO:0055087 Ski complex(GO:0055087)
0.1 0.7 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 1.0 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 0.7 GO:0005796 Golgi lumen(GO:0005796)
0.1 2.0 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.8 GO:0030061 mitochondrial crista(GO:0030061)
0.1 1.7 GO:0017119 Golgi transport complex(GO:0017119)
0.1 1.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 1.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 2.2 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189)
0.1 1.3 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 0.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.8 GO:0005787 signal peptidase complex(GO:0005787)
0.1 1.4 GO:0031011 Ino80 complex(GO:0031011)
0.1 1.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.6 GO:0033263 CORVET complex(GO:0033263)
0.1 1.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 3.5 GO:0005801 cis-Golgi network(GO:0005801)
0.1 3.7 GO:0031201 SNARE complex(GO:0031201)
0.1 14.5 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.9 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.5 GO:0036501 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) UFD1-NPL4 complex(GO:0036501)
0.1 3.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 3.6 GO:0005776 autophagosome(GO:0005776)
0.1 7.5 GO:0055037 recycling endosome(GO:0055037)
0.1 0.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 1.5 GO:0005795 Golgi stack(GO:0005795)
0.0 0.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 1.9 GO:0005811 lipid droplet(GO:0005811)
0.0 10.5 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 2.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 3.1 GO:0072562 blood microparticle(GO:0072562)
0.0 1.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.4 GO:0060076 excitatory synapse(GO:0060076)
0.0 1.3 GO:0099086 synaptonemal complex(GO:0000795) synaptonemal structure(GO:0099086)
0.0 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 7.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.0 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 2.7 GO:0001650 fibrillar center(GO:0001650)
0.0 2.5 GO:0030018 Z disc(GO:0030018)
0.0 6.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.5 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 1.5 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 3.2 GO:0016607 nuclear speck(GO:0016607)
0.0 1.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
1.4 6.8 GO:0016623 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
1.3 3.9 GO:0072541 peroxynitrite reductase activity(GO:0072541)
1.2 4.8 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
1.1 3.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
1.0 2.9 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.6 4.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.6 1.7 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.6 5.7 GO:0001594 trace-amine receptor activity(GO:0001594)
0.6 7.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.5 1.6 GO:0070905 serine binding(GO:0070905)
0.5 2.7 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.5 1.4 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.5 1.4 GO:0036478 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) protein deglycase activity(GO:0036524)
0.4 1.3 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.4 2.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.3 1.0 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.3 3.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 0.9 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.3 5.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.3 2.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 1.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.3 1.0 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 3.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 1.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.2 1.6 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.2 1.5 GO:0070568 guanylyltransferase activity(GO:0070568)
0.2 5.0 GO:0097602 cullin family protein binding(GO:0097602)
0.2 1.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.2 4.0 GO:0070577 lysine-acetylated histone binding(GO:0070577) acetylation-dependent protein binding(GO:0140033)
0.2 1.4 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.2 9.1 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.2 0.8 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 1.6 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 1.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 1.8 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 2.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.7 GO:0015250 water channel activity(GO:0015250)
0.1 5.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 3.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 1.8 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 4.0 GO:0030552 cAMP binding(GO:0030552)
0.1 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 10.8 GO:0020037 heme binding(GO:0020037)
0.1 1.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 3.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 3.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.8 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding(GO:0070530)
0.1 1.0 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 2.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.5 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 3.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 1.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.9 GO:0031386 protein tag(GO:0031386)
0.1 1.1 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 2.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.9 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 1.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 6.2 GO:0000149 SNARE binding(GO:0000149)
0.1 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 3.5 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 5.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 1.0 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 1.3 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.5 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 6.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 3.4 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.4 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 0.8 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.3 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.1 GO:0019213 deacetylase activity(GO:0019213)
0.0 2.1 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 3.7 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 1.9 GO:0005506 iron ion binding(GO:0005506)
0.0 3.7 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.4 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.9 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 1.1 GO:0005179 hormone activity(GO:0005179)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.1 4.2 PID_ARF_3PATHWAY Arf1 pathway
0.1 6.0 PID_IL1_PATHWAY IL1-mediated signaling events
0.1 4.7 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 2.0 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 0.8 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 4.1 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.5 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.2 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 5.5 PID_LKB1_PATHWAY LKB1 signaling events
0.1 1.7 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.1 1.1 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.1 3.1 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.3 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 1.8 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 2.7 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.4 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 2.1 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 1.2 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.4 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.9 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID_FOXO_PATHWAY FoxO family signaling
0.0 1.8 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 1.0 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.7 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.5 9.1 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3 5.2 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 3.7 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.2 6.0 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 3.1 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.2 2.5 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.2 2.0 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 11.4 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 1.8 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.2 1.7 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.7 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.8 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.7 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 4.2 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 4.0 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.1 1.3 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 0.8 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 2.1 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 0.9 REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 1.2 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 2.4 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 9.9 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 1.6 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 3.3 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.1 REACTOME_TRNA_AMINOACYLATION Genes involved in tRNA Aminoacylation
0.1 1.5 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 1.8 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.7 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 1.1 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.0 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 1.5 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 1.5 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.3 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 3.9 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins