Motif ID: Cux1

Z-value: 1.379


Transcription factors associated with Cux1:

Gene SymbolEntrez IDGene Name
Cux1 ENSMUSG00000029705.11 Cux1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cux1mm10_v2_chr5_-_136567307_136567445-0.642.8e-05Click!


Activity profile for motif Cux1.

activity profile for motif Cux1


Sorted Z-values histogram for motif Cux1

Sorted Z-values for motif Cux1



Network of associatons between targets according to the STRING database.



First level regulatory network of Cux1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_39287074 17.890 ENSMUST00000003137.8
Cyp2c29
cytochrome P450, family 2, subfamily c, polypeptide 29
chr4_+_63344548 11.992 ENSMUST00000030044.2
Orm1
orosomucoid 1
chr4_-_62150810 10.064 ENSMUST00000077719.3
Mup21
major urinary protein 21
chr13_-_4523322 9.527 ENSMUST00000080361.5
ENSMUST00000078239.3
Akr1c20

aldo-keto reductase family 1, member C20

chr15_+_6445320 9.415 ENSMUST00000022749.9
C9
complement component 9
chr3_-_81975742 8.534 ENSMUST00000029645.8
Tdo2
tryptophan 2,3-dioxygenase
chr19_+_39992424 8.247 ENSMUST00000049178.2
Cyp2c37
cytochrome P450, family 2. subfamily c, polypeptide 37
chr7_-_99695809 7.916 ENSMUST00000107086.2
Slco2b1
solute carrier organic anion transporter family, member 2b1
chr19_+_40089688 7.733 ENSMUST00000068094.6
ENSMUST00000080171.2
Cyp2c50

cytochrome P450, family 2, subfamily c, polypeptide 50

chr7_-_99695628 7.295 ENSMUST00000145381.1
Slco2b1
solute carrier organic anion transporter family, member 2b1
chr7_-_99695572 6.924 ENSMUST00000137914.1
Slco2b1
solute carrier organic anion transporter family, member 2b1
chr19_+_39007019 6.813 ENSMUST00000025966.4
Cyp2c55
cytochrome P450, family 2, subfamily c, polypeptide 55
chr19_-_44407703 6.583 ENSMUST00000041331.2
Scd1
stearoyl-Coenzyme A desaturase 1
chr7_+_27029074 6.557 ENSMUST00000075552.5
Cyp2a12
cytochrome P450, family 2, subfamily a, polypeptide 12
chr7_+_44384098 6.489 ENSMUST00000118962.1
ENSMUST00000118831.1
Syt3

synaptotagmin III

chr7_+_44384803 6.361 ENSMUST00000120262.1
Syt3
synaptotagmin III
chr11_+_78499087 6.185 ENSMUST00000017488.4
Vtn
vitronectin
chr1_+_166254095 5.993 ENSMUST00000111416.1
Ildr2
immunoglobulin-like domain containing receptor 2
chr19_-_40073731 5.981 ENSMUST00000048959.3
Cyp2c54
cytochrome P450, family 2, subfamily c, polypeptide 54
chr7_+_27119909 5.936 ENSMUST00000003100.8
Cyp2f2
cytochrome P450, family 2, subfamily f, polypeptide 2
chr2_+_102706356 5.844 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr13_+_4436094 5.511 ENSMUST00000156277.1
Akr1c6
aldo-keto reductase family 1, member C6
chr9_+_46268601 5.482 ENSMUST00000121598.1
Apoa5
apolipoprotein A-V
chr7_-_19698383 5.358 ENSMUST00000173739.1
Apoe
apolipoprotein E
chr2_-_24049389 5.174 ENSMUST00000051416.5
Hnmt
histamine N-methyltransferase
chr8_+_109990430 4.912 ENSMUST00000001720.7
ENSMUST00000143741.1
Tat

tyrosine aminotransferase

chr11_-_72266596 4.854 ENSMUST00000021161.6
ENSMUST00000140167.1
Slc13a5

solute carrier family 13 (sodium-dependent citrate transporter), member 5

chr7_+_44384604 4.831 ENSMUST00000130707.1
ENSMUST00000130844.1
Syt3

synaptotagmin III

chr8_-_94696223 4.615 ENSMUST00000034227.4
Pllp
plasma membrane proteolipid
chr7_-_19698206 4.536 ENSMUST00000172808.1
ENSMUST00000174191.1
Apoe

apolipoprotein E

chr5_-_89457763 4.446 ENSMUST00000049209.8
Gc
group specific component
chr10_+_62071014 4.411 ENSMUST00000053865.5
Gm5424
predicted gene 5424
chr6_+_121346618 4.332 ENSMUST00000032200.9
Slc6a12
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
chr9_-_119157055 4.247 ENSMUST00000010795.4
Acaa1b
acetyl-Coenzyme A acyltransferase 1B
chr7_+_44590886 4.245 ENSMUST00000107906.3
Kcnc3
potassium voltage gated channel, Shaw-related subfamily, member 3
chr11_-_58613481 3.973 ENSMUST00000048801.7
2210407C18Rik
RIKEN cDNA 2210407C18 gene
chr7_-_140154712 3.906 ENSMUST00000059241.7
Sprn
shadow of prion protein
chr7_-_14492926 3.893 ENSMUST00000108524.3
Sult2a7
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 7
chr3_+_138374121 3.835 ENSMUST00000171054.1
Adh6-ps1
alcohol dehydrogenase 6 (class V), pseudogene 1
chr17_+_24736639 3.766 ENSMUST00000115262.1
Msrb1
methionine sulfoxide reductase B1
chr12_+_108334341 3.731 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr5_-_87254804 3.631 ENSMUST00000075858.3
Ugt2b37
UDP glucuronosyltransferase 2 family, polypeptide B37
chr6_-_128526703 3.569 ENSMUST00000143664.1
ENSMUST00000112132.1
ENSMUST00000032510.7
Pzp


pregnancy zone protein


chr1_+_58113136 3.536 ENSMUST00000040999.7
Aox3
aldehyde oxidase 3
chr19_-_43524462 3.531 ENSMUST00000026196.7
Got1
glutamate oxaloacetate transaminase 1, soluble
chr7_-_132576372 3.518 ENSMUST00000084500.6
Oat
ornithine aminotransferase
chr13_-_41847482 3.470 ENSMUST00000072012.3
Adtrp
androgen dependent TFPI regulating protein
chr9_+_114731177 3.449 ENSMUST00000035007.8
Cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr1_-_162898665 3.420 ENSMUST00000111510.1
ENSMUST00000045902.6
Fmo2

flavin containing monooxygenase 2

chr1_-_162898484 3.394 ENSMUST00000143123.1
Fmo2
flavin containing monooxygenase 2
chr19_-_4839286 3.380 ENSMUST00000037246.5
Ccs
copper chaperone for superoxide dismutase
chr3_+_94372794 3.363 ENSMUST00000029795.3
Rorc
RAR-related orphan receptor gamma
chr2_-_166155272 3.306 ENSMUST00000088086.3
Sulf2
sulfatase 2
chr6_-_90224438 3.291 ENSMUST00000076086.2
Vmn1r53
vomeronasal 1 receptor 53
chr12_-_103904887 3.277 ENSMUST00000074051.5
Serpina1c
serine (or cysteine) peptidase inhibitor, clade A, member 1C
chr12_-_103773592 3.274 ENSMUST00000078869.5
Serpina1d
serine (or cysteine) peptidase inhibitor, clade A, member 1D
chr11_-_50325599 3.175 ENSMUST00000179865.1
ENSMUST00000020637.8
Canx

calnexin

chrM_+_10167 3.157 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr7_-_26939377 3.139 ENSMUST00000170227.1
Cyp2a22
cytochrome P450, family 2, subfamily a, polypeptide 22
chr1_+_78511865 3.135 ENSMUST00000012331.6
Mogat1
monoacylglycerol O-acyltransferase 1
chr18_-_38211957 3.122 ENSMUST00000159405.1
ENSMUST00000160721.1
Pcdh1

protocadherin 1

chr7_-_35215248 3.068 ENSMUST00000118444.1
ENSMUST00000122409.1
Lrp3

low density lipoprotein receptor-related protein 3

chr2_+_31887262 3.055 ENSMUST00000138325.1
ENSMUST00000028187.6
Lamc3

laminin gamma 3

chr17_+_24736673 3.031 ENSMUST00000101800.5
Msrb1
methionine sulfoxide reductase B1
chr13_+_4059565 2.984 ENSMUST00000041768.6
Akr1c14
aldo-keto reductase family 1, member C14
chr5_-_87140318 2.955 ENSMUST00000067790.6
ENSMUST00000113327.1
Ugt2b5

UDP glucuronosyltransferase 2 family, polypeptide B5

chr11_-_116198701 2.948 ENSMUST00000072948.4
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr14_-_47189406 2.902 ENSMUST00000089959.6
Gch1
GTP cyclohydrolase 1
chr2_-_164638789 2.875 ENSMUST00000109336.1
Wfdc16
WAP four-disulfide core domain 16
chr11_+_75468040 2.852 ENSMUST00000043598.7
ENSMUST00000108435.1
Tlcd2

TLC domain containing 2

chr11_-_96916366 2.843 ENSMUST00000144731.1
ENSMUST00000127048.1
Cdk5rap3

CDK5 regulatory subunit associated protein 3

chr2_-_86347764 2.803 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chrX_+_101383726 2.798 ENSMUST00000119190.1
Gjb1
gap junction protein, beta 1
chr2_-_32694120 2.750 ENSMUST00000028148.4
Fpgs
folylpolyglutamyl synthetase
chr13_+_93674403 2.724 ENSMUST00000048001.6
Dmgdh
dimethylglycine dehydrogenase precursor
chr5_-_147894804 2.677 ENSMUST00000118527.1
ENSMUST00000031655.3
ENSMUST00000138244.1
Slc46a3


solute carrier family 46, member 3


chr11_-_96916448 2.676 ENSMUST00000103152.4
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr11_-_74925925 2.653 ENSMUST00000121738.1
Srr
serine racemase
chrX_-_8193387 2.645 ENSMUST00000143223.1
ENSMUST00000033509.8
Ebp

phenylalkylamine Ca2+ antagonist (emopamil) binding protein

chr12_-_103863551 2.632 ENSMUST00000085056.6
ENSMUST00000072876.5
ENSMUST00000124717.1
Serpina1a


serine (or cysteine) peptidase inhibitor, clade A, member 1A


chr5_+_33104219 2.632 ENSMUST00000011178.2
Slc5a1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr10_-_75780954 2.620 ENSMUST00000173537.1
ENSMUST00000173512.1
Gstt3
Gm20441
glutathione S-transferase, theta 3
predicted gene 20441
chr19_+_45076105 2.603 ENSMUST00000026234.4
Kazald1
Kazal-type serine peptidase inhibitor domain 1
chr4_-_63154130 2.582 ENSMUST00000030041.4
Ambp
alpha 1 microglobulin/bikunin
chrX_+_101377267 2.542 ENSMUST00000052130.7
Gjb1
gap junction protein, beta 1
chr11_+_51763682 2.535 ENSMUST00000020653.5
Sar1b
SAR1 gene homolog B (S. cerevisiae)
chr11_-_50931612 2.527 ENSMUST00000109124.3
Zfp354b
zinc finger protein 354B
chr4_+_62360695 2.500 ENSMUST00000084526.5
Slc31a1
solute carrier family 31, member 1
chr13_-_34130345 2.486 ENSMUST00000075774.3
Tubb2b
tubulin, beta 2B class IIB
chr1_+_88070765 2.474 ENSMUST00000073772.4
Ugt1a9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr1_-_180256294 2.438 ENSMUST00000111108.3
Psen2
presenilin 2
chrX_+_142228177 2.424 ENSMUST00000112914.1
Nxt2
nuclear transport factor 2-like export factor 2
chr15_+_88819584 2.335 ENSMUST00000024042.3
Creld2
cysteine-rich with EGF-like domains 2
chr1_+_88200601 2.334 ENSMUST00000049289.8
Ugt1a2
UDP glucuronosyltransferase 1 family, polypeptide A2
chr5_+_3596066 2.325 ENSMUST00000006061.6
ENSMUST00000121291.1
ENSMUST00000142516.1
Pex1


peroxisomal biogenesis factor 1


chr12_-_103738158 2.319 ENSMUST00000095450.4
Serpina1b
serine (or cysteine) preptidase inhibitor, clade A, member 1B
chr11_-_96916407 2.303 ENSMUST00000130774.1
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr8_-_77610597 2.289 ENSMUST00000034030.8
Tmem184c
transmembrane protein 184C
chr7_-_27674516 2.279 ENSMUST00000036453.7
ENSMUST00000108341.1
Map3k10

mitogen-activated protein kinase kinase kinase 10

chr12_+_24572276 2.268 ENSMUST00000085553.5
Grhl1
grainyhead-like 1 (Drosophila)
chr9_-_50746501 2.257 ENSMUST00000034564.1
2310030G06Rik
RIKEN cDNA 2310030G06 gene
chr1_-_179546261 2.234 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr9_-_26999491 2.224 ENSMUST00000060513.7
ENSMUST00000120367.1
Acad8

acyl-Coenzyme A dehydrogenase family, member 8

chr4_+_104766334 2.208 ENSMUST00000065072.6
C8b
complement component 8, beta polypeptide
chr6_+_88724828 2.191 ENSMUST00000089449.2
Mgll
monoglyceride lipase
chr13_-_34963788 2.180 ENSMUST00000164155.1
ENSMUST00000021853.5
Eci3

enoyl-Coenzyme A delta isomerase 3

chr19_-_39649046 2.178 ENSMUST00000067328.6
Cyp2c67
cytochrome P450, family 2, subfamily c, polypeptide 67
chrX_+_7722267 2.167 ENSMUST00000125991.1
ENSMUST00000148624.1
Wdr45

WD repeat domain 45

chr6_-_124741374 2.162 ENSMUST00000004389.5
Grcc10
gene rich cluster, C10 gene
chr5_-_87424201 2.162 ENSMUST00000072818.5
Ugt2b38
UDP glucuronosyltransferase 2 family, polypeptide B38
chr4_-_148160031 2.157 ENSMUST00000057907.3
Fbxo44
F-box protein 44
chr1_+_16688405 2.156 ENSMUST00000026881.4
Ly96
lymphocyte antigen 96
chr11_+_73199445 2.154 ENSMUST00000006105.6
Shpk
sedoheptulokinase
chr6_-_114969986 2.148 ENSMUST00000139640.1
Vgll4
vestigial like 4 (Drosophila)
chr6_+_48395586 2.147 ENSMUST00000114571.1
ENSMUST00000114572.3
ENSMUST00000031815.5
Krba1


KRAB-A domain containing 1


chrX_+_142227923 2.123 ENSMUST00000042329.5
Nxt2
nuclear transport factor 2-like export factor 2
chr11_-_53423123 2.121 ENSMUST00000036045.5
Leap2
liver-expressed antimicrobial peptide 2
chr2_-_84775388 2.096 ENSMUST00000023994.3
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr15_+_99392948 2.094 ENSMUST00000161250.1
ENSMUST00000160635.1
ENSMUST00000161778.1
Tmbim6


transmembrane BAX inhibitor motif containing 6


chr10_-_127121125 2.092 ENSMUST00000164259.1
ENSMUST00000080975.4
Os9

amplified in osteosarcoma

chrM_+_7005 2.084 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr2_-_84775420 2.081 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chrX_+_7722214 2.068 ENSMUST00000043045.2
ENSMUST00000116634.1
ENSMUST00000115689.3
ENSMUST00000131077.1
ENSMUST00000115688.1
ENSMUST00000116633.1
Wdr45





WD repeat domain 45





chr8_+_94525067 1.980 ENSMUST00000098489.4
Nlrc5
NLR family, CARD domain containing 5
chr7_+_24587543 1.965 ENSMUST00000077191.6
Ethe1
ethylmalonic encephalopathy 1
chr3_-_85722474 1.940 ENSMUST00000119077.1
Fam160a1
family with sequence similarity 160, member A1
chr9_-_101034857 1.933 ENSMUST00000142676.1
ENSMUST00000149322.1
Pccb

propionyl Coenzyme A carboxylase, beta polypeptide

chr3_-_107239707 1.919 ENSMUST00000049852.8
Prok1
prokineticin 1
chr14_+_118137101 1.906 ENSMUST00000022728.2
Gpr180
G protein-coupled receptor 180
chr6_+_48395652 1.901 ENSMUST00000077093.4
Krba1
KRAB-A domain containing 1
chr3_+_19957037 1.894 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chrM_+_9870 1.859 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr8_-_77610668 1.846 ENSMUST00000141202.1
ENSMUST00000152168.1
Tmem184c

transmembrane protein 184C

chr9_-_101034892 1.846 ENSMUST00000035116.5
Pccb
propionyl Coenzyme A carboxylase, beta polypeptide
chr11_-_106487796 1.781 ENSMUST00000001059.2
ENSMUST00000106799.1
ENSMUST00000106800.1
Ern1


endoplasmic reticulum (ER) to nucleus signalling 1


chr6_+_124931378 1.780 ENSMUST00000032214.7
ENSMUST00000180095.1
Mlf2

myeloid leukemia factor 2

chr5_+_90561102 1.773 ENSMUST00000094615.4
5830473C10Rik
RIKEN cDNA 5830473C10 gene
chr4_+_43493345 1.760 ENSMUST00000030181.5
ENSMUST00000107922.2
Ccdc107

coiled-coil domain containing 107

chr4_+_104766308 1.753 ENSMUST00000031663.3
C8b
complement component 8, beta polypeptide
chr11_-_101171302 1.744 ENSMUST00000164474.1
ENSMUST00000043397.7
Plekhh3

pleckstrin homology domain containing, family H (with MyTH4 domain) member 3

chr3_-_89279633 1.737 ENSMUST00000118860.1
ENSMUST00000029566.2
Efna1

ephrin A1

chr12_+_55598917 1.729 ENSMUST00000051857.3
Insm2
insulinoma-associated 2
chr9_+_46240696 1.724 ENSMUST00000034585.6
Apoa4
apolipoprotein A-IV
chr1_+_21218575 1.709 ENSMUST00000027065.5
ENSMUST00000027064.7
Tmem14a

transmembrane protein 14A

chr1_-_84284548 1.707 ENSMUST00000177458.1
ENSMUST00000168574.2
Pid1

phosphotyrosine interaction domain containing 1

chr17_-_23786046 1.702 ENSMUST00000024704.3
Flywch2
FLYWCH family member 2
chr4_-_141933080 1.696 ENSMUST00000036701.7
Fhad1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr18_-_56562261 1.696 ENSMUST00000066208.6
ENSMUST00000172734.1
Aldh7a1

aldehyde dehydrogenase family 7, member A1

chr19_-_42128982 1.693 ENSMUST00000161873.1
Avpi1
arginine vasopressin-induced 1
chr1_-_24612700 1.691 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chrX_+_36795642 1.685 ENSMUST00000016463.3
Slc25a5
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
chr4_+_116596672 1.684 ENSMUST00000051869.7
Ccdc17
coiled-coil domain containing 17
chr1_+_78511805 1.679 ENSMUST00000152111.1
Mogat1
monoacylglycerol O-acyltransferase 1
chr6_-_130231638 1.677 ENSMUST00000088011.4
ENSMUST00000112013.1
ENSMUST00000049304.7
Klra7


killer cell lectin-like receptor, subfamily A, member 7


chr3_-_88296838 1.673 ENSMUST00000010682.3
Tsacc
TSSK6 activating co-chaperone
chr3_-_63964659 1.666 ENSMUST00000161659.1
Slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr17_+_46711459 1.661 ENSMUST00000002840.8
Pex6
peroxisomal biogenesis factor 6
chr3_+_19957088 1.657 ENSMUST00000108328.1
Cp
ceruloplasmin
chr7_-_137410717 1.651 ENSMUST00000120340.1
ENSMUST00000117404.1
ENSMUST00000068996.6
9430038I01Rik


RIKEN cDNA 9430038I01 gene


chr1_+_106171752 1.645 ENSMUST00000061047.6
Phlpp1
PH domain and leucine rich repeat protein phosphatase 1
chr3_-_88296979 1.608 ENSMUST00000107556.3
Tsacc
TSSK6 activating co-chaperone
chr5_+_24428208 1.589 ENSMUST00000115049.2
Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr17_-_24220738 1.585 ENSMUST00000024930.7
1600002H07Rik
RIKEN cDNA 1600002H07 gene
chr7_-_101921186 1.565 ENSMUST00000106965.1
ENSMUST00000106968.1
ENSMUST00000106967.1
Lrrc51


leucine rich repeat containing 51


chr11_+_96251100 1.545 ENSMUST00000129907.2
Gm53
predicted gene 53
chr15_+_76660564 1.538 ENSMUST00000004294.10
Kifc2
kinesin family member C2
chr3_+_19957240 1.537 ENSMUST00000108325.2
Cp
ceruloplasmin
chrX_-_60893430 1.524 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr4_-_148151646 1.510 ENSMUST00000132083.1
Fbxo6
F-box protein 6
chr14_-_59365465 1.496 ENSMUST00000095157.4
Phf11d
PHD finger protein 11D
chrX_+_152001845 1.496 ENSMUST00000026289.3
ENSMUST00000112617.3
Hsd17b10

hydroxysteroid (17-beta) dehydrogenase 10

chr5_+_124541296 1.487 ENSMUST00000124529.1
Tmed2
transmembrane emp24 domain trafficking protein 2
chr18_+_37447641 1.480 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr2_-_110305730 1.467 ENSMUST00000046233.2
Bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr11_-_105944128 1.459 ENSMUST00000184086.1
Cyb561
cytochrome b-561
chr16_+_70314087 1.441 ENSMUST00000023393.8
Gbe1
glucan (1,4-alpha-), branching enzyme 1
chr12_+_57564111 1.418 ENSMUST00000101398.3
Ttc6
tetratricopeptide repeat domain 6
chr7_-_24587612 1.418 ENSMUST00000094705.2
Zfp575
zinc finger protein 575
chr12_-_103956891 1.416 ENSMUST00000085054.4
Serpina1e
serine (or cysteine) peptidase inhibitor, clade A, member 1E
chr19_+_43782181 1.409 ENSMUST00000026208.4
Abcc2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr8_+_11497506 1.409 ENSMUST00000177955.1
ENSMUST00000033901.4
ENSMUST00000178721.1
Carkd


carbohydrate kinase domain containing


chr7_-_140881811 1.402 ENSMUST00000106048.3
ENSMUST00000147331.2
ENSMUST00000137710.1
Sirt3


sirtuin 3


chr1_+_107361929 1.397 ENSMUST00000027566.2
Serpinb11
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
chr4_-_118134869 1.395 ENSMUST00000097912.1
ENSMUST00000030263.2
ENSMUST00000106410.1
St3gal3


ST3 beta-galactoside alpha-2,3-sialyltransferase 3


chr6_-_24527546 1.395 ENSMUST00000118558.1
Ndufa5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr10_+_125966214 1.392 ENSMUST00000074807.6
Lrig3
leucine-rich repeats and immunoglobulin-like domains 3
chr6_+_48554776 1.392 ENSMUST00000114545.1
ENSMUST00000153222.1
ENSMUST00000101436.2
Lrrc61


leucine rich repeat containing 61


chr10_-_42478488 1.384 ENSMUST00000041024.8
Lace1
lactation elevated 1
chr13_+_55714624 1.380 ENSMUST00000021959.9
Txndc15
thioredoxin domain containing 15
chr11_-_96075581 1.378 ENSMUST00000107686.1
ENSMUST00000107684.1
Atp5g1

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)

chrM_+_7759 1.372 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr9_-_50727921 1.371 ENSMUST00000118707.1
ENSMUST00000034566.8
Dixdc1

DIX domain containing 1

chr7_+_67647405 1.367 ENSMUST00000032774.8
ENSMUST00000107471.1
Ttc23

tetratricopeptide repeat domain 23

chr4_+_95557494 1.362 ENSMUST00000079223.4
ENSMUST00000177394.1
Fggy

FGGY carbohydrate kinase domain containing

chr16_+_29579331 1.356 ENSMUST00000160597.1
Opa1
optic atrophy 1
chr9_+_107578887 1.345 ENSMUST00000149638.1
ENSMUST00000139274.1
ENSMUST00000130053.1
ENSMUST00000122985.1
ENSMUST00000127380.1
ENSMUST00000139581.1
Nat6





N-acetyltransferase 6





chr11_+_108921648 1.338 ENSMUST00000144511.1
Axin2
axin2
chr7_+_113207465 1.331 ENSMUST00000047321.7
Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr15_+_44196135 1.325 ENSMUST00000038856.6
ENSMUST00000110289.3
Trhr

thyrotropin releasing hormone receptor

chr4_-_91399984 1.315 ENSMUST00000102799.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 22.1 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
3.3 9.9 GO:1905890 cellular response to very-low-density lipoprotein particle stimulus(GO:0090731) negative regulation of presynaptic membrane organization(GO:1901630) regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002) regulation of heparan sulfate binding(GO:1905853) positive regulation of heparan sulfate binding(GO:1905855) regulation of heparan sulfate proteoglycan binding(GO:1905858) positive regulation of heparan sulfate proteoglycan binding(GO:1905860) regulation of cellular response to very-low-density lipoprotein particle stimulus(GO:1905890)
2.8 8.5 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
1.9 62.7 GO:0019373 epoxygenase P450 pathway(GO:0019373)
1.8 5.5 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
1.6 6.6 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
1.4 1.4 GO:0050787 detoxification of mercury ion(GO:0050787)
1.4 4.2 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.4 5.5 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
1.2 4.9 GO:0015744 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
1.2 4.8 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
1.2 3.5 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
1.1 4.3 GO:0009992 cellular water homeostasis(GO:0009992)
1.1 6.4 GO:0072592 oxygen metabolic process(GO:0072592)
1.0 5.2 GO:0001692 histamine metabolic process(GO:0001692)
1.0 9.0 GO:0071569 protein ufmylation(GO:0071569)
1.0 4.9 GO:0006572 tyrosine catabolic process(GO:0006572)
1.0 6.8 GO:0030091 protein repair(GO:0030091)
0.9 2.8 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.9 9.5 GO:0097421 liver regeneration(GO:0097421)
0.8 13.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.8 5.8 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.7 5.2 GO:0030969 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.7 3.0 GO:1901337 fatty-acyl-CoA transport(GO:0015916) thioester transport(GO:1901337)
0.7 2.9 GO:0014916 regulation of lung blood pressure(GO:0014916)
0.7 15.0 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.7 3.5 GO:0009115 xanthine catabolic process(GO:0009115)
0.6 2.5 GO:0072719 cellular response to cisplatin(GO:0072719)
0.6 4.6 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.6 1.7 GO:0034443 negative regulation of lipoprotein oxidation(GO:0034443) multicellular organismal lipid catabolic process(GO:0044240)
0.6 1.7 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.5 2.2 GO:0036343 psychomotor behavior(GO:0036343)
0.5 2.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.5 2.2 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.5 2.7 GO:0070178 D-amino acid metabolic process(GO:0046416) D-serine metabolic process(GO:0070178)
0.5 3.5 GO:0034214 protein hexamerization(GO:0034214)
0.5 2.9 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.5 1.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.4 1.3 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.4 0.9 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.4 2.7 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.4 1.7 GO:0014028 notochord formation(GO:0014028)
0.4 1.3 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365)
0.4 1.3 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.4 4.8 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.4 3.7 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.4 1.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.3 1.7 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.3 2.7 GO:0019695 choline metabolic process(GO:0019695)
0.3 1.0 GO:1905258 regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway(GO:1905258) negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway(GO:1905259)
0.3 7.0 GO:0015865 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.3 1.6 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.3 0.9 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.3 2.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.3 1.2 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.3 3.4 GO:0072615 interleukin-17 secretion(GO:0072615)
0.3 1.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3 2.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.3 16.6 GO:0006953 acute-phase response(GO:0006953)
0.3 0.9 GO:0006538 glutamate catabolic process(GO:0006538)
0.3 4.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.3 4.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.3 0.8 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.3 1.3 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.3 1.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.3 1.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.3 2.6 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.3 0.8 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.3 2.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 2.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 2.0 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.2 2.0 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.2 2.2 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.2 0.7 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.2 0.9 GO:0045054 constitutive secretory pathway(GO:0045054)
0.2 2.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 0.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 2.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 2.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.2 0.9 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.2 0.9 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066) guanosine-containing compound catabolic process(GO:1901069)
0.2 0.6 GO:0016132 brassinosteroid metabolic process(GO:0016131) brassinosteroid biosynthetic process(GO:0016132)
0.2 0.6 GO:1905034 regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035)
0.2 1.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.2 0.6 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.2 3.8 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.2 0.8 GO:0070295 renal water absorption(GO:0070295)
0.2 5.1 GO:0046688 response to copper ion(GO:0046688)
0.2 1.1 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.2 0.9 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 0.7 GO:1903445 protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.2 0.7 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.2 1.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 2.5 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.2 1.1 GO:0032790 ribosome disassembly(GO:0032790)
0.2 2.3 GO:0002934 desmosome organization(GO:0002934)
0.2 0.9 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.7 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.1 0.7 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.3 GO:0060459 left lung development(GO:0060459) left lung morphogenesis(GO:0060460)
0.1 3.4 GO:0019430 removal of superoxide radicals(GO:0019430)
0.1 2.3 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 0.8 GO:0015889 cobalamin transport(GO:0015889)
0.1 2.1 GO:0051382 kinetochore assembly(GO:0051382)
0.1 2.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 9.3 GO:0022900 electron transport chain(GO:0022900)
0.1 0.5 GO:0022615 protein to membrane docking(GO:0022615) negative regulation of exosomal secretion(GO:1903542)
0.1 1.0 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.2 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1 0.4 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 1.0 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 3.7 GO:0019236 response to pheromone(GO:0019236)
0.1 0.6 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 5.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.4 GO:0042407 cristae formation(GO:0042407)
0.1 0.7 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.6 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 1.0 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.4 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.1 0.3 GO:0014732 skeletal muscle atrophy(GO:0014732) striated muscle atrophy(GO:0014891)
0.1 0.3 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 0.4 GO:0061734 parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization(GO:0061734)
0.1 1.0 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.9 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.1 0.6 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.5 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.1 0.3 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.1 1.5 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.3 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.1 0.9 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 4.4 GO:0051180 vitamin transport(GO:0051180)
0.1 0.2 GO:0042697 menopause(GO:0042697)
0.1 2.4 GO:0014002 astrocyte development(GO:0014002)
0.1 1.5 GO:0021854 hypothalamus development(GO:0021854)
0.1 0.3 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1 0.6 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.1 0.6 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 0.3 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 7.0 GO:0009062 fatty acid catabolic process(GO:0009062)
0.1 5.7 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 0.2 GO:0001806 type IV hypersensitivity(GO:0001806)
0.1 0.8 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.3 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.1 1.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.4 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) pyrimidine nucleobase biosynthetic process(GO:0019856) UMP metabolic process(GO:0046049)
0.1 0.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.7 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 1.2 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.4 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.1 3.2 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 0.9 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 1.0 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.1 0.6 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.1 16.6 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 1.9 GO:0097503 sialylation(GO:0097503)
0.1 0.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 2.6 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 1.0 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 0.5 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.3 GO:0021508 ventral midline development(GO:0007418) floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.1 0.2 GO:0032430 reduction of food intake in response to dietary excess(GO:0002023) positive regulation of phospholipase A2 activity(GO:0032430)
0.0 0.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.9 GO:0035634 response to stilbenoid(GO:0035634)
0.0 0.6 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.3 GO:0051715 cytolysis in other organism(GO:0051715)
0.0 1.2 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.6 GO:0060253 negative regulation of glial cell proliferation(GO:0060253)
0.0 4.7 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.9 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.7 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.2 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.4 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.7 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 1.0 GO:0048240 sperm capacitation(GO:0048240)
0.0 1.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:0031000 response to caffeine(GO:0031000)
0.0 0.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 2.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 2.0 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.8 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.3 GO:2000786 positive regulation of vacuole organization(GO:0044090) positive regulation of autophagosome assembly(GO:2000786)
0.0 0.3 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 1.4 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.6 GO:2000310 regulation of NMDA receptor activity(GO:2000310)
0.0 0.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.4 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.6 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 1.2 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.7 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.6 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.2 GO:0036444 mitochondrial calcium uptake(GO:0036444)
0.0 0.5 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.4 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.6 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.7 GO:0010107 potassium ion import(GO:0010107)
0.0 0.6 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.6 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.0 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.8 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.4 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 1.5 GO:0007034 vacuolar transport(GO:0007034)
0.0 0.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.5 GO:0031638 zymogen activation(GO:0031638)
0.0 0.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.5 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.4 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.6 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.1 GO:2000138 positive regulation of sarcomere organization(GO:0060298) positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0 0.3 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 1.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.5 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 1.3 GO:0006626 protein targeting to mitochondrion(GO:0006626)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.4 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
2.0 9.9 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.9 6.2 GO:0005796 Golgi lumen(GO:0005796)
0.5 2.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.4 2.7 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.4 3.1 GO:1990597 AIP1-IRE1 complex(GO:1990597) IRE1-TRAF2-ASK1 complex(GO:1990604)
0.4 1.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.4 1.6 GO:0070552 BRISC complex(GO:0070552)
0.4 4.0 GO:0005579 membrane attack complex(GO:0005579)
0.4 4.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.4 6.6 GO:0042627 chylomicron(GO:0042627)
0.4 5.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3 1.7 GO:0030891 VCB complex(GO:0030891)
0.3 3.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.3 1.7 GO:0071817 MMXD complex(GO:0071817)
0.3 2.1 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.3 23.3 GO:0009925 basal plasma membrane(GO:0009925)
0.3 1.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 10.1 GO:0030673 axolemma(GO:0030673)
0.2 5.1 GO:0005922 connexin complex(GO:0005922)
0.2 1.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 2.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 0.9 GO:0098993 anchored component of synaptic vesicle membrane(GO:0098993)
0.2 4.6 GO:0043218 compact myelin(GO:0043218)
0.2 1.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 6.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.4 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.3 GO:0016939 kinesin II complex(GO:0016939)
0.1 10.6 GO:0070469 respiratory chain(GO:0070469)
0.1 1.0 GO:0036128 CatSper complex(GO:0036128)
0.1 1.4 GO:0097470 ribbon synapse(GO:0097470) synaptic ribbon(GO:0098681)
0.1 1.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 2.9 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.7 GO:0002081 outer acrosomal membrane(GO:0002081)
0.1 2.2 GO:0043196 varicosity(GO:0043196)
0.1 0.5 GO:1990393 3M complex(GO:1990393)
0.1 6.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 7.4 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 1.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.8 GO:0016272 prefoldin complex(GO:0016272)
0.1 3.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.9 GO:0048787 early phagosome(GO:0032009) presynaptic active zone membrane(GO:0048787)
0.1 1.3 GO:0033391 chromatoid body(GO:0033391)
0.1 0.9 GO:0042588 zymogen granule(GO:0042588)
0.1 0.6 GO:0061617 MICOS complex(GO:0061617)
0.1 0.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.0 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 0.9 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.9 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 0.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.3 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.1 0.7 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 0.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 8.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 0.8 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189)
0.1 89.9 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.5 GO:0036157 outer dynein arm(GO:0036157)
0.0 3.7 GO:0031526 brush border membrane(GO:0031526)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 17.1 GO:0098793 presynapse(GO:0098793)
0.0 0.8 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 5.1 GO:0005770 late endosome(GO:0005770)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 3.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 3.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 1.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.3 GO:0097542 ciliary tip(GO:0097542)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 3.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:0030134 COPII-coated ER to Golgi transport vesicle(GO:0030134)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 1.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.8 GO:0030139 endocytic vesicle(GO:0030139)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 20.5 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
3.3 9.9 GO:0046911 metal chelating activity(GO:0046911)
3.1 18.6 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
2.8 8.4 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
2.1 8.5 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
1.8 5.5 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
1.6 6.6 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
1.6 4.9 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
1.4 7.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
1.3 3.8 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
1.2 4.8 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
1.1 6.8 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
1.1 4.4 GO:1902271 D3 vitamins binding(GO:1902271)
1.1 23.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
1.0 3.0 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
1.0 5.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.9 2.7 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.9 23.6 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.7 4.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.7 3.5 GO:0016623 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.7 6.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.7 2.7 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.7 3.4 GO:0008142 oxysterol binding(GO:0008142)
0.7 3.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.6 3.2 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.6 2.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.6 3.4 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.6 1.7 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.6 2.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.5 5.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5 2.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.5 3.0 GO:0051185 coenzyme transporter activity(GO:0051185)
0.5 2.9 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.5 1.5 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.5 1.4 GO:0019150 D-ribulokinase activity(GO:0019150)
0.5 5.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.4 2.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.4 1.7 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.4 1.3 GO:0034046 poly(G) binding(GO:0034046)
0.4 9.1 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.4 2.9 GO:0019238 cyclohydrolase activity(GO:0019238)
0.4 3.4 GO:1901612 cardiolipin binding(GO:1901612)
0.4 1.4 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.4 3.6 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.4 13.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.3 2.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.3 1.3 GO:1905394 retromer complex binding(GO:1905394)
0.3 5.3 GO:0005243 gap junction channel activity(GO:0005243)
0.3 2.6 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.3 4.2 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.3 7.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.3 2.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.3 1.2 GO:0004568 chitinase activity(GO:0004568)
0.3 0.9 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.3 0.9 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867)
0.3 0.9 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.3 8.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 15.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.3 0.8 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.3 3.6 GO:0070403 NAD+ binding(GO:0070403)
0.2 1.5 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.2 0.7 GO:0030350 iron-responsive element binding(GO:0030350)
0.2 3.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 6.2 GO:0030247 polysaccharide binding(GO:0030247)
0.2 0.6 GO:0009918 sterol delta7 reductase activity(GO:0009918) 7-dehydrocholesterol reductase activity(GO:0047598)
0.2 2.5 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.2 1.0 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901) sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590)
0.2 0.6 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.2 5.7 GO:0001848 complement binding(GO:0001848)
0.2 2.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.2 0.7 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 0.9 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 0.9 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.2 0.9 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.2 0.6 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.2 3.5 GO:0008483 transaminase activity(GO:0008483)
0.2 1.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 3.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 1.0 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931)
0.1 4.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 1.0 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 2.6 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 3.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.7 GO:1902944 aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902944)
0.1 0.9 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 15.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.4 GO:0046870 cadmium ion binding(GO:0046870)
0.1 0.1 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.4 GO:0003878 ATP citrate synthase activity(GO:0003878)
0.1 0.8 GO:0015288 porin activity(GO:0015288)
0.1 0.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 2.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 2.8 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.8 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 2.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 2.0 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 2.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.2 GO:0019972 interleukin-12 binding(GO:0019972)
0.1 0.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 1.8 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 2.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 1.3 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.2 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.1 0.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.3 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 0.4 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.3 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.4 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 0.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 2.7 GO:0005549 odorant binding(GO:0005549)
0.1 0.3 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 2.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.3 GO:0038100 nodal binding(GO:0038100)
0.1 2.6 GO:0050699 WW domain binding(GO:0050699)
0.1 0.4 GO:0015220 choline transmembrane transporter activity(GO:0015220) choline binding(GO:0033265)
0.1 1.4 GO:0031489 myosin V binding(GO:0031489)
0.1 2.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0001586 Gi/o-coupled serotonin receptor activity(GO:0001586)
0.0 0.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 1.0 GO:0070410 co-SMAD binding(GO:0070410)
0.0 1.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.5 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.8 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750) ribose-5-phosphate isomerase activity(GO:0004751) sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity(GO:0004801)
0.0 2.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 1.4 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.3 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.6 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.2 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 1.0 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 2.3 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 2.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 1.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.0 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 1.1 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.3 GO:0022848 acetylcholine-gated cation-selective channel activity(GO:0022848)
0.0 0.5 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.7 GO:0001540 amyloid-beta binding(GO:0001540)
0.0 2.9 GO:0005125 cytokine activity(GO:0005125)
0.0 0.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 1.2 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.1 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 3.1 GO:0030246 carbohydrate binding(GO:0030246)
0.0 2.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.6 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 0.0 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229) intracellular chloride channel activity(GO:0061778)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.2 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 3.8 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.6 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 2.7 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 4.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.7 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 2.3 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.1 3.1 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 4.9 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 14.6 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 1.3 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 1.2 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 1.3 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 1.8 PID_FGF_PATHWAY FGF signaling pathway
0.0 1.3 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.7 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.5 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 2.4 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.7 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.7 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 0.3 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.3 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.9 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.8 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 1.6 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.8 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.7 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.1 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.7 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.7 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID_BCR_5PATHWAY BCR signaling pathway
0.0 0.3 PID_NETRIN_PATHWAY Netrin-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 22.1 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.7 17.6 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.5 8.5 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.4 14.7 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.3 4.9 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.3 3.7 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.3 3.2 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.3 5.1 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.2 3.0 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 5.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 3.8 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 4.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 3.4 REACTOME_SIGNALING_BY_NOTCH2 Genes involved in Signaling by NOTCH2
0.2 3.7 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.2 7.6 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 2.5 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.2 4.2 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.2 3.7 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.6 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 4.4 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.1 3.6 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 3.2 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 2.9 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.2 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 3.7 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.1 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 3.3 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 2.3 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.2 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.7 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 0.7 REACTOME_AMYLOIDS Genes involved in Amyloids
0.1 2.0 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.8 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.3 REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 0.8 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 3.1 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.7 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.9 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.7 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 0.6 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 8.2 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 1.6 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 2.9 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 1.3 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.7 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.6 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.7 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 3.3 REACTOME_UNFOLDED_PROTEIN_RESPONSE Genes involved in Unfolded Protein Response
0.0 1.4 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 2.4 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.1 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 2.6 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 5.6 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.5 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.7 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 2.0 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.2 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.7 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.9 REACTOME_PI_METABOLISM Genes involved in PI Metabolism
0.0 0.2 REACTOME_MEIOSIS Genes involved in Meiosis
0.0 0.3 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation