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GSE58827: Dynamics of the Mouse Liver

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Results for Dlx1

Z-value: 2.25

Motif logo

Transcription factors associated with Dlx1

Gene Symbol Gene ID Gene Info
ENSMUSG00000041911.3 distal-less homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Dlx1mm10_v2_chr2_+_71528657_715286830.421.1e-02Click!

Activity profile of Dlx1 motif

Sorted Z-values of Dlx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_84988194 25.05 ENSMUST00000028466.5
proteoglycan 3
chr19_-_34166037 23.70 ENSMUST00000025686.7
ankyrin repeat domain 22
chr11_+_87793470 22.49 ENSMUST00000020779.4
myeloperoxidase
chr14_+_80000292 19.08 ENSMUST00000088735.3
olfactomedin 4
chr1_+_131638306 17.67 ENSMUST00000073350.6
cathepsin E
chr11_+_58918004 17.64 ENSMUST00000108818.3
ENSMUST00000020792.5
butyrophilin-like 10
chr16_+_36277145 15.53 ENSMUST00000042097.9
stefin A1
chr1_+_40439767 15.06 ENSMUST00000173514.1
interleukin 1 receptor-like 1
chr17_+_40811089 14.71 ENSMUST00000024721.7
Rhesus blood group-associated A glycoprotein
chr11_+_58917889 14.58 ENSMUST00000069941.6
butyrophilin-like 10
chr14_+_27000362 13.90 ENSMUST00000035433.8
homeobox gene expressed in ES cells
chr4_+_34893772 13.23 ENSMUST00000029975.3
ENSMUST00000135871.1
ENSMUST00000108130.1
glycoprotein hormones, alpha subunit
chr1_+_40439627 12.03 ENSMUST00000097772.3
interleukin 1 receptor-like 1
chr1_-_132390301 11.91 ENSMUST00000132435.1
transmembrane and coiled-coil domains 2
chr2_+_131491764 10.77 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
spermine oxidase
chr6_+_41354105 10.72 ENSMUST00000072103.5
trypsin 10
chr6_+_30541582 10.57 ENSMUST00000096066.4
carboxypeptidase A2, pancreatic
chr9_-_123678782 10.44 ENSMUST00000170591.1
ENSMUST00000171647.1
solute carrier family 6 (neurotransmitter transporter), member 20A
chr5_-_108749448 10.26 ENSMUST00000068946.7
ring finger protein 212
chr6_-_40999479 10.25 ENSMUST00000166306.1
predicted gene 2663
chr1_+_107535508 10.12 ENSMUST00000182198.1
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
chr2_-_126500631 9.93 ENSMUST00000129187.1
ATPase, class I, type 8B, member 4
chr3_-_75270073 9.79 ENSMUST00000039047.4
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr17_-_48432723 9.73 ENSMUST00000046549.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr8_-_85380964 9.27 ENSMUST00000122452.1
myosin light chain kinase 3
chr5_+_90768511 9.25 ENSMUST00000031319.6
pro-platelet basic protein
chr12_+_109540979 9.08 ENSMUST00000129245.1
ENSMUST00000143836.1
ENSMUST00000124106.1
maternally expressed 3
chr17_+_5799491 9.07 ENSMUST00000181484.1
RIKEN cDNA 3300005D01 gene
chr7_-_119459266 9.04 ENSMUST00000033255.5
glycoprotein 2 (zymogen granule membrane)
chr13_+_104229366 8.89 ENSMUST00000022227.6
centromere protein K
chr9_-_123678873 8.82 ENSMUST00000040960.6
solute carrier family 6 (neurotransmitter transporter), member 20A
chr7_-_133702515 8.76 ENSMUST00000153698.1
uroporphyrinogen III synthase
chr14_+_32321987 8.69 ENSMUST00000022480.7
oxoglutarate dehydrogenase-like
chr8_-_4779513 8.47 ENSMUST00000022945.7
Shc SH2-domain binding protein 1
chr19_-_40588374 8.01 ENSMUST00000175932.1
ENSMUST00000176955.1
ENSMUST00000149476.2
aldehyde dehydrogenase 18 family, member A1
chr19_+_58759700 7.82 ENSMUST00000026081.3
pancreatic lipase-related protein 2
chr5_-_43981757 7.81 ENSMUST00000061299.7
fibroblast growth factor binding protein 1
chr1_-_93342734 7.81 ENSMUST00000027493.3
PAS domain containing serine/threonine kinase
chr8_+_94172618 7.69 ENSMUST00000034214.6
metallothionein 2
chr3_-_113258837 7.64 ENSMUST00000098673.3
amylase 2a5
chr16_-_75909272 7.63 ENSMUST00000114239.2
SAM domain, SH3 domain and nuclear localization signals, 1
chr3_-_20275659 7.59 ENSMUST00000011607.5
carboxypeptidase B1 (tissue)
chr15_+_44457522 7.48 ENSMUST00000166957.1
ENSMUST00000038336.5
polycystic kidney and hepatic disease 1-like 1
chr19_-_40588338 7.47 ENSMUST00000176939.1
aldehyde dehydrogenase 18 family, member A1
chr2_+_119047116 7.42 ENSMUST00000152380.1
ENSMUST00000099542.2
cancer susceptibility candidate 5
chr15_-_36879816 7.18 ENSMUST00000100713.2
predicted gene 10384
chr15_+_84232030 7.12 ENSMUST00000023072.6
parvin, beta
chr11_+_83437678 6.89 ENSMUST00000037378.4
RIKEN cDNA 1700020L24 gene
chr6_-_36811361 6.87 ENSMUST00000101534.1
pleiotrophin
chr3_-_116253467 6.86 ENSMUST00000090473.5
G-protein coupled receptor 88
chr10_+_115817247 6.73 ENSMUST00000035563.7
ENSMUST00000080630.3
ENSMUST00000179196.1
tetraspanin 8
chr9_+_65890237 6.68 ENSMUST00000045802.6
RIKEN cDNA 2810417H13 gene
chrX_+_150547375 6.65 ENSMUST00000066337.6
ENSMUST00000112715.1
aminolevulinic acid synthase 2, erythroid
chr17_-_35027909 6.58 ENSMUST00000040151.2
suppressor APC domain containing 1
chr8_+_23411490 6.51 ENSMUST00000033952.7
secreted frizzled-related protein 1
chr3_-_14778452 6.42 ENSMUST00000094365.4
carbonic anhydrase 1
chr11_+_69045640 6.40 ENSMUST00000108666.1
ENSMUST00000021277.5
aurora kinase B
chr14_+_118787894 6.22 ENSMUST00000047761.6
ENSMUST00000071546.7
claudin 10
chr9_-_58741543 6.17 ENSMUST00000098674.4
RIKEN cDNA 2410076I21 gene
chr18_-_74207771 6.06 ENSMUST00000040188.8
ENSMUST00000177604.1
spindle and kinetochore associated complex subunit 1
chr1_+_139454747 6.01 ENSMUST00000053364.8
ENSMUST00000097554.3
asp (abnormal spindle)-like, microcephaly associated (Drosophila)
chr9_-_95750335 5.98 ENSMUST00000053785.3
transient receptor potential cation channel, subfamily C, member 1
chr2_-_121235689 5.96 ENSMUST00000142400.1
transformation related protein 53 binding protein 1
chr6_+_123172893 5.91 ENSMUST00000088455.5
C-type lectin domain family 4, member b2
chr12_-_101028983 5.86 ENSMUST00000068411.3
ENSMUST00000085096.3
coiled-coil domain containing 88C
chr11_-_106314494 5.84 ENSMUST00000167143.1
CD79B antigen
chr3_-_113291449 5.79 ENSMUST00000179568.1
amylase 2a4
chr9_-_21963568 5.65 ENSMUST00000006397.5
erythropoietin receptor
chr7_+_43427622 5.64 ENSMUST00000177164.2
lens intrinsic membrane protein 2
chr13_-_23551648 5.52 ENSMUST00000102971.1
histone cluster 1, H4f
chr16_+_32756336 5.49 ENSMUST00000135753.1
mucin 4
chr11_+_11487671 5.48 ENSMUST00000020410.4
RIKEN cDNA 4930415F15 gene
chr12_-_115790884 5.35 ENSMUST00000081809.5
immunoglobulin heavy variable 1-73
chr8_+_116921735 5.33 ENSMUST00000034205.4
centromere protein N
chr9_+_119063429 5.27 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
villin-like
chr14_+_118854695 5.25 ENSMUST00000100314.3
claudin 10
chr8_-_62123106 5.15 ENSMUST00000034052.6
ENSMUST00000034054.7
annexin A10
chr6_-_129275360 5.14 ENSMUST00000032259.3
CD69 antigen
chr1_-_126830632 5.13 ENSMUST00000112583.1
ENSMUST00000094609.3
NCK-associated protein 5
chr10_+_119992916 5.08 ENSMUST00000105261.2
glutamate receptor interacting protein 1
chr2_+_109280738 5.03 ENSMUST00000028527.7
kinesin family member 18A
chr13_+_52596847 4.98 ENSMUST00000055087.6
spleen tyrosine kinase
chr12_-_55014329 4.97 ENSMUST00000172875.1
bromodomain adjacent to zinc finger domain 1A
chr12_+_108605757 4.96 ENSMUST00000109854.2
Ena-vasodilator stimulated phosphoprotein
chrX_-_74246534 4.96 ENSMUST00000101454.2
ENSMUST00000033699.6
filamin, alpha
chr10_-_6980376 4.90 ENSMUST00000105617.1
interaction protein for cytohesin exchange factors 1
chr10_-_62527438 4.88 ENSMUST00000160987.1
serglycin
chr10_-_62527413 4.81 ENSMUST00000160643.1
serglycin
chr13_+_44729535 4.80 ENSMUST00000174068.1
jumonji, AT rich interactive domain 2
chr3_-_106219477 4.74 ENSMUST00000082219.5
chitinase 3-like 4
chr11_+_74082907 4.66 ENSMUST00000178159.1
zinc finger protein 616
chr7_-_25005895 4.64 ENSMUST00000102858.3
ENSMUST00000080882.6
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr5_-_30945393 4.59 ENSMUST00000031051.6
cell growth regulator with EF hand domain 1
chr10_+_119992962 4.55 ENSMUST00000154238.1
glutamate receptor interacting protein 1
chr13_+_23544052 4.44 ENSMUST00000075558.2
histone cluster 1, H3f
chrX_-_160906998 4.38 ENSMUST00000069417.5
gap junction protein, alpha 6
chr6_-_122340525 4.35 ENSMUST00000112600.2
polyhomeotic-like 1 (Drosophila)
chrX_-_53114530 4.29 ENSMUST00000114843.2
placental specific protein 1
chr2_+_85979312 4.28 ENSMUST00000170610.1
olfactory receptor 1030
chr3_-_10254213 4.27 ENSMUST00000172126.1
ENSMUST00000117917.1
fatty acid binding protein 12
chr10_-_62422427 4.25 ENSMUST00000020277.8
hexokinase domain containing 1
chr4_-_132075250 4.19 ENSMUST00000105970.1
ENSMUST00000105975.1
erythrocyte protein band 4.1
chr5_+_141856692 4.15 ENSMUST00000074546.6
sidekick homolog 1 (chicken)
chr2_+_84839395 4.15 ENSMUST00000146816.1
ENSMUST00000028469.7
solute carrier family 43, member 1
chr1_-_172895048 4.07 ENSMUST00000027824.5
serum amyloid P-component
chr17_+_34914459 4.06 ENSMUST00000007249.8
solute carrier family 44, member 4
chr6_-_122340499 4.05 ENSMUST00000160843.1
polyhomeotic-like 1 (Drosophila)
chr13_-_95525239 4.03 ENSMUST00000022185.8
coagulation factor II (thrombin) receptor-like 1
chr2_-_160619971 4.03 ENSMUST00000109473.1
predicted gene 14221
chr15_-_34356421 4.01 ENSMUST00000179647.1
RIKEN cDNA 9430069I07 gene
chr8_+_119700009 3.98 ENSMUST00000095171.3
ATPase, Ca++ transporting, type 2C, member 2
chr2_+_119047129 3.98 ENSMUST00000153300.1
ENSMUST00000028799.5
cancer susceptibility candidate 5
chr14_+_61309753 3.94 ENSMUST00000055159.7
ADP-ribosylation factor-like 11
chr3_-_27153861 3.94 ENSMUST00000108300.1
ENSMUST00000108298.2
ect2 oncogene
chr6_-_50456085 3.87 ENSMUST00000146341.1
ENSMUST00000071728.4
oxysterol binding protein-like 3
chr7_+_141746736 3.84 ENSMUST00000026590.8
mucin 2
chr19_-_32196393 3.72 ENSMUST00000151822.1
sphingomyelin synthase 1
chr12_-_87444017 3.71 ENSMUST00000091090.4
RIKEN cDNA 2700073G19 gene
chr9_-_57836706 3.71 ENSMUST00000164010.1
ENSMUST00000171444.1
ENSMUST00000098686.3
AT rich interactive domain 3B (BRIGHT-like)
chr10_-_76110956 3.69 ENSMUST00000120757.1
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr17_-_26099257 3.69 ENSMUST00000053575.3
predicted gene 8186
chr14_-_104522615 3.66 ENSMUST00000022716.2
ring finger protein 219
chr19_+_55180799 3.65 ENSMUST00000025936.5
tectorin beta
chr7_+_45621805 3.61 ENSMUST00000033100.4
izumo sperm-egg fusion 1
chr11_-_69895523 3.57 ENSMUST00000001631.6
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr2_+_4300462 3.57 ENSMUST00000175669.1
FERM domain containing 4A
chr16_-_69863718 3.52 ENSMUST00000076500.7
spermatogenesis associated glutamate (E)-rich protein 2
chr6_+_72097561 3.51 ENSMUST00000069994.4
ENSMUST00000114112.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr13_-_58354862 3.41 ENSMUST00000043605.5
kinesin family member 27
chr19_-_55241236 3.40 ENSMUST00000069183.6
guanylate cyclase 2g
chr3_+_146121655 3.35 ENSMUST00000039450.4
mucolipin 3
chr6_+_122513643 3.31 ENSMUST00000118626.1
microfibrillar associated protein 5
chr2_-_73453918 3.30 ENSMUST00000102679.1
WAS/WASL interacting protein family, member 1
chrX_-_57338598 3.28 ENSMUST00000033468.4
ENSMUST00000114736.1
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr19_+_34100943 3.27 ENSMUST00000025685.6
lipase, family member M
chr9_-_36726374 3.25 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
checkpoint kinase 1
chr6_-_129876659 3.24 ENSMUST00000014687.4
ENSMUST00000122219.1
killer cell lectin-like receptor, subfamily A, member 17
chr17_+_8236031 3.24 ENSMUST00000164411.2
chemokine (C-C motif) receptor 6
chr18_-_23981555 3.19 ENSMUST00000115829.1
zinc finger and SCAN domain containing 30
chr3_-_17230976 3.19 ENSMUST00000177874.1
predicted gene 5283
chr19_-_50678642 3.16 ENSMUST00000072685.6
ENSMUST00000164039.2
VPS10 domain receptor protein SORCS 1
chr16_+_92478743 3.16 ENSMUST00000160494.1
RIKEN cDNA 2410124H12 gene
chr9_-_21312255 3.15 ENSMUST00000115433.3
ENSMUST00000003397.7
adaptor protein complex AP-1, mu 2 subunit
chr4_+_145585166 3.15 ENSMUST00000105739.1
ENSMUST00000119718.1
predicted gene 13212
chr10_-_129902726 3.13 ENSMUST00000071557.1
olfactory receptor 815
chr6_+_122513583 3.08 ENSMUST00000032210.7
ENSMUST00000148517.1
microfibrillar associated protein 5
chr19_-_11604828 3.02 ENSMUST00000025582.4
membrane-spanning 4-domains, subfamily A, member 6D
chr19_-_38043559 3.02 ENSMUST00000041475.8
ENSMUST00000172095.2
myoferlin
chr7_+_27452417 3.01 ENSMUST00000108357.1
biliverdin reductase B (flavin reductase (NADPH))
chr4_-_41464816 3.00 ENSMUST00000108055.2
ENSMUST00000154535.1
ENSMUST00000030148.5
kinesin family member 24
chr2_-_85675173 2.99 ENSMUST00000099917.1
olfactory receptor 1006
chr18_+_44104407 2.97 ENSMUST00000081271.5
serine peptidase inhibitor, Kazal type 11
chr16_-_3908596 2.97 ENSMUST00000123235.2
RIKEN cDNA 1700037C18 gene
chr18_+_37518341 2.96 ENSMUST00000097609.1
protocadherin beta 22
chr19_+_53140430 2.96 ENSMUST00000111741.2
adducin 3 (gamma)
chr13_+_23555023 2.95 ENSMUST00000045301.6
histone cluster 1, H1d
chr12_+_102128718 2.95 ENSMUST00000159329.1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr5_+_100845709 2.95 ENSMUST00000144623.1
1-acylglycerol-3-phosphate O-acyltransferase 9
chr1_+_86021935 2.95 ENSMUST00000052854.6
ENSMUST00000125083.1
ENSMUST00000152501.1
ENSMUST00000113344.1
ENSMUST00000130504.1
ENSMUST00000153247.2
spermatogenesis associated 3
chr2_-_113848655 2.93 ENSMUST00000102545.1
ENSMUST00000110948.1
Rho GTPase activating protein 11A
chr1_-_172027251 2.93 ENSMUST00000138714.1
vang-like 2 (van gogh, Drosophila)
chr12_+_55124528 2.91 ENSMUST00000177768.1
family with sequence similarity 177, member A
chr2_-_164171113 2.91 ENSMUST00000045196.3
K+ voltage-gated channel, subfamily S, 1
chr9_-_90255927 2.89 ENSMUST00000144646.1
TBC1 domain family, member 2B
chr3_-_130730375 2.86 ENSMUST00000079085.6
ribosomal protein L34
chr15_+_92344359 2.76 ENSMUST00000181901.1
predicted gene, 26760
chr10_+_80264942 2.76 ENSMUST00000105362.1
ENSMUST00000105361.3
DAZ associated protein 1
chr2_-_34913976 2.76 ENSMUST00000028232.3
PHD finger protein 19
chr2_+_91650116 2.70 ENSMUST00000111331.2
Rho GTPase activating protein 1
chr1_+_58210397 2.69 ENSMUST00000040442.5
aldehyde oxidase 4
chrX_+_153139941 2.65 ENSMUST00000039720.4
ENSMUST00000144175.2
Ras-related GTP binding B
chr4_+_12906838 2.65 ENSMUST00000143186.1
ENSMUST00000183345.1
triple QxxK/R motif containing
chr13_+_23575753 2.64 ENSMUST00000105105.1
histone cluster 1, H3d
chr7_-_101869307 2.64 ENSMUST00000140584.1
ENSMUST00000134145.1
folate receptor 1 (adult)
chr6_-_128275577 2.62 ENSMUST00000130454.1
TEA domain family member 4
chr6_+_78370877 2.60 ENSMUST00000096904.3
regenerating islet-derived 3 beta
chr4_-_154928187 2.59 ENSMUST00000123514.1
tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
chr4_+_101507947 2.56 ENSMUST00000149047.1
ENSMUST00000106929.3
DnaJ (Hsp40) homolog, subfamily C, member 6
chr17_-_47016956 2.54 ENSMUST00000165525.1
predicted gene 16494
chrY_+_90785442 2.51 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
erythroid differentiation regulator 1
chr5_+_19907502 2.51 ENSMUST00000101558.3
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr13_-_62371936 2.50 ENSMUST00000107989.3
predicted gene 3604
chr10_-_88605017 2.46 ENSMUST00000119185.1
ENSMUST00000121629.1
myosin binding protein C, slow-type
chrX_-_164250368 2.45 ENSMUST00000112263.1
BMX non-receptor tyrosine kinase
chr2_-_120154600 2.45 ENSMUST00000028755.7
EH-domain containing 4
chrX_-_8074720 2.44 ENSMUST00000115636.3
ENSMUST00000115638.3
suppressor of variegation 3-9 homolog 1 (Drosophila)
chr3_+_59952185 2.43 ENSMUST00000094227.3
predicted gene 9696
chr16_+_38346986 2.38 ENSMUST00000050273.8
ENSMUST00000120495.1
ENSMUST00000119704.1
cytochrome c oxidase assembly protein 17
predicted gene 21987
chr17_-_31129602 2.38 ENSMUST00000024827.4
trefoil factor 3, intestinal
chr10_-_51631458 2.36 ENSMUST00000020062.3
G protein-coupled receptor, family C, group 6, member A
chr4_+_146654927 2.36 ENSMUST00000070932.3
predicted gene 13248
chr12_-_12940600 2.36 ENSMUST00000130990.1
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr2_+_69219971 2.35 ENSMUST00000005364.5
ENSMUST00000112317.2
glucose-6-phosphatase, catalytic, 2
chr8_-_21456560 2.34 ENSMUST00000110752.3
predicted gene 7849
chr9_-_62026788 2.34 ENSMUST00000034817.4
progestin and adipoQ receptor family member V
chr4_+_62525369 2.33 ENSMUST00000062145.1
RIKEN cDNA 4933430I17 gene
chr12_+_84069325 2.31 ENSMUST00000046422.4
ENSMUST00000072505.4
acyl-CoA thioesterase 5
chr19_+_23723279 2.30 ENSMUST00000067077.1
predicted gene 9938
chr7_+_84853573 2.29 ENSMUST00000078172.4
olfactory receptor 291
chr17_+_17316078 2.28 ENSMUST00000105311.3
predicted gene 6712

Network of associatons between targets according to the STRING database.

First level regulatory network of Dlx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 22.5 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
6.5 26.1 GO:0045575 basophil activation(GO:0045575)
5.2 15.5 GO:0006592 ornithine biosynthetic process(GO:0006592)
4.9 14.7 GO:0072488 ammonium transmembrane transport(GO:0072488)
4.8 19.3 GO:0035524 proline transmembrane transport(GO:0035524)
2.6 28.8 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
2.4 9.7 GO:0033380 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
2.4 2.4 GO:1904732 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
2.4 7.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
2.3 6.9 GO:0061743 motor learning(GO:0061743)
2.2 8.8 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
2.2 6.5 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
2.1 6.4 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
2.1 10.3 GO:0006311 meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
1.7 6.9 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
1.7 5.1 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.7 5.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
1.5 9.3 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
1.5 10.8 GO:0046208 spermine catabolic process(GO:0046208)
1.5 14.9 GO:0030916 otic vesicle formation(GO:0030916)
1.4 5.5 GO:0002838 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
1.4 1.4 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
1.4 4.1 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
1.3 4.0 GO:1900135 positive regulation of eosinophil degranulation(GO:0043311) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949) positive regulation of renin secretion into blood stream(GO:1900135) positive regulation of eosinophil activation(GO:1902568)
1.2 5.0 GO:0032672 regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425) cellular response to molecule of fungal origin(GO:0071226)
1.2 3.6 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
1.2 6.0 GO:0051661 maintenance of centrosome location(GO:0051661)
1.2 20.2 GO:0016540 protein autoprocessing(GO:0016540)
1.1 7.7 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
1.0 1.0 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
1.0 7.8 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
1.0 9.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.9 13.2 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.9 1.8 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.8 4.2 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.8 5.0 GO:0032439 endosome localization(GO:0032439) negative regulation of vacuolar transport(GO:1903336)
0.8 3.2 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.7 4.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.7 2.2 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.7 2.2 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.7 4.3 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.7 7.8 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.7 4.2 GO:0072592 oxygen metabolic process(GO:0072592)
0.7 2.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.6 1.3 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.6 2.3 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.6 7.4 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.5 2.7 GO:0009115 xanthine catabolic process(GO:0009115)
0.5 2.6 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.5 3.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.5 6.0 GO:0046541 saliva secretion(GO:0046541)
0.5 1.9 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.5 4.6 GO:0036376 sodium ion export from cell(GO:0036376)
0.5 9.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.4 7.6 GO:0019377 glycolipid catabolic process(GO:0019377)
0.4 4.9 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.4 4.8 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.4 2.6 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.4 2.6 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.4 2.6 GO:0072318 clathrin coat disassembly(GO:0072318)
0.4 1.3 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.4 3.7 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.4 5.6 GO:0061032 visceral serous pericardium development(GO:0061032)
0.4 1.6 GO:0015827 angiotensin-mediated drinking behavior(GO:0003051) aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.4 6.0 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.4 2.8 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.4 1.2 GO:0045006 DNA deamination(GO:0045006)
0.4 5.0 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.4 3.0 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.4 5.9 GO:0002579 positive regulation of antigen processing and presentation(GO:0002579)
0.4 3.0 GO:0016584 nucleosome positioning(GO:0016584)
0.4 1.8 GO:0015819 lysine transport(GO:0015819)
0.4 3.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.4 1.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.4 1.1 GO:0061738 mitotic cytokinesis checkpoint(GO:0044878) late endosomal microautophagy(GO:0061738) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.3 1.0 GO:0070543 response to linoleic acid(GO:0070543)
0.3 5.5 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.3 4.8 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 2.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.3 8.9 GO:0008340 determination of adult lifespan(GO:0008340)
0.3 8.5 GO:0097435 fibril organization(GO:0097435)
0.3 1.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.3 16.9 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.3 3.6 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.3 3.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 2.6 GO:0071231 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.3 1.7 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.3 2.9 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.3 0.6 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.3 1.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.3 0.8 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.3 2.4 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.3 1.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3 3.7 GO:1904659 glucose transmembrane transport(GO:1904659)
0.3 1.0 GO:1905154 negative regulation of membrane invagination(GO:1905154)
0.3 1.0 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.3 0.8 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.2 7.6 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.2 0.5 GO:1900239 regulation of phenotypic switching(GO:1900239)
0.2 2.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2 6.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 3.0 GO:0001778 plasma membrane repair(GO:0001778)
0.2 1.4 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.2 3.9 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 0.7 GO:0061193 taste bud development(GO:0061193)
0.2 1.8 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.2 1.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.2 1.6 GO:0006265 DNA topological change(GO:0006265)
0.2 2.4 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2 0.4 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2 0.4 GO:0002309 T cell proliferation involved in immune response(GO:0002309) CD4-positive, alpha-beta T cell proliferation(GO:0035739)
0.2 5.3 GO:0034508 centromere complex assembly(GO:0034508)
0.2 0.8 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.2 11.9 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.2 1.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 4.3 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.2 11.2 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.2 2.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 5.7 GO:0019236 response to pheromone(GO:0019236)
0.2 4.1 GO:0072520 seminiferous tubule development(GO:0072520)
0.2 0.7 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.2 0.7 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.2 1.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 2.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 0.6 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 8.6 GO:0050819 negative regulation of coagulation(GO:0050819)
0.2 1.8 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.7 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 1.2 GO:0051013 microtubule severing(GO:0051013)
0.1 0.4 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 1.3 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.6 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.1 2.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 3.3 GO:0006907 pinocytosis(GO:0006907)
0.1 1.3 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 1.2 GO:0016191 synaptic vesicle uncoating(GO:0016191) vesicle uncoating(GO:0072319)
0.1 8.4 GO:0016574 histone ubiquitination(GO:0016574)
0.1 2.1 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 6.3 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 4.1 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 1.0 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.1 3.4 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.1 5.1 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 2.9 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 4.7 GO:0051693 actin filament capping(GO:0051693)
0.1 3.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 2.4 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 0.6 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 10.5 GO:0007586 digestion(GO:0007586)
0.1 1.0 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 1.2 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.1 2.3 GO:0097186 amelogenesis(GO:0097186)
0.1 2.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 1.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 3.4 GO:0021591 ventricular system development(GO:0021591)
0.1 1.0 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 10.8 GO:0007030 Golgi organization(GO:0007030)
0.1 0.2 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 3.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 10.1 GO:0031109 microtubule polymerization or depolymerization(GO:0031109)
0.1 3.5 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.1 1.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 2.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 7.3 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.1 3.4 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.1 5.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 1.3 GO:0002504 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.1 1.1 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.3 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.1 0.4 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.1 1.2 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 2.2 GO:1901016 regulation of potassium ion transmembrane transporter activity(GO:1901016)
0.1 0.5 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1 0.9 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 2.5 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 12.4 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 1.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 2.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 2.2 GO:0007566 embryo implantation(GO:0007566)
0.0 4.2 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.7 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.3 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.6 GO:0071420 cellular response to histamine(GO:0071420)
0.0 2.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 4.6 GO:0007050 cell cycle arrest(GO:0007050)
0.0 2.1 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.4 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 1.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 3.2 GO:0060998 regulation of dendritic spine development(GO:0060998)
0.0 0.9 GO:0031424 keratinization(GO:0031424)
0.0 0.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 1.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 1.3 GO:0030804 positive regulation of cyclic nucleotide biosynthetic process(GO:0030804)
0.0 1.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 2.0 GO:0034101 erythrocyte homeostasis(GO:0034101)
0.0 0.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 2.2 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.8 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.1 GO:0040031 snRNA modification(GO:0040031)
0.0 0.3 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 1.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.0 GO:1904923 regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.0 1.6 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.1 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 19.1 GO:0042581 specific granule(GO:0042581)
1.5 10.8 GO:0019815 B cell receptor complex(GO:0019815)
1.4 22.5 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
1.3 5.1 GO:0060187 cell pole(GO:0060187)
1.2 5.0 GO:0008623 CHRAC(GO:0008623)
1.2 6.0 GO:0036449 microtubule minus-end(GO:0036449)
1.1 6.4 GO:0032133 chromosome passenger complex(GO:0032133)
1.0 5.0 GO:0031523 Myb complex(GO:0031523)
0.9 9.7 GO:0042629 mast cell granule(GO:0042629)
0.9 1.7 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.8 8.4 GO:0001739 sex chromatin(GO:0001739)
0.8 4.2 GO:0070826 paraferritin complex(GO:0070826)
0.8 5.0 GO:0097443 sorting endosome(GO:0097443)
0.8 3.9 GO:0097149 centralspindlin complex(GO:0097149)
0.7 5.0 GO:0005828 kinetochore microtubule(GO:0005828)
0.7 7.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.6 8.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.6 7.8 GO:0042589 zymogen granule membrane(GO:0042589)
0.5 2.7 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.5 4.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.5 8.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.5 2.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.5 1.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.4 1.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.4 1.8 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.4 3.7 GO:0000138 Golgi trans cisterna(GO:0000138)
0.4 1.1 GO:0030312 external encapsulating structure(GO:0030312)
0.3 3.0 GO:0097524 sperm plasma membrane(GO:0097524)
0.3 5.3 GO:0019814 immunoglobulin complex(GO:0019814)
0.3 2.5 GO:0071438 invadopodium membrane(GO:0071438)
0.3 7.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 2.6 GO:0042588 zymogen granule(GO:0042588)
0.2 9.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 1.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 0.9 GO:0005594 collagen type IX trimer(GO:0005594)
0.2 4.0 GO:0031143 pseudopodium(GO:0031143)
0.2 1.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 5.5 GO:0031528 microvillus membrane(GO:0031528)
0.2 7.8 GO:0000786 nucleosome(GO:0000786)
0.2 0.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 4.4 GO:0005922 connexon complex(GO:0005922)
0.2 2.2 GO:0032797 SMN complex(GO:0032797)
0.2 0.6 GO:0035841 new growing cell tip(GO:0035841)
0.1 1.3 GO:0000243 commitment complex(GO:0000243)
0.1 6.0 GO:0035861 site of double-strand break(GO:0035861)
0.1 2.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 2.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 1.7 GO:0005687 U4 snRNP(GO:0005687)
0.1 2.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.7 GO:0034709 methylosome(GO:0034709)
0.1 3.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.9 GO:0097422 tubular endosome(GO:0097422)
0.1 1.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.9 GO:0031932 TORC2 complex(GO:0031932)
0.1 20.0 GO:0005923 bicellular tight junction(GO:0005923)
0.1 5.9 GO:0043034 costamere(GO:0043034)
0.1 1.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 2.5 GO:0005859 muscle myosin complex(GO:0005859)
0.1 3.6 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 41.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 6.4 GO:0005871 kinesin complex(GO:0005871)
0.1 1.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 11.2 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 11.9 GO:0000776 kinetochore(GO:0000776)
0.1 10.8 GO:0072562 blood microparticle(GO:0072562)
0.1 0.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 1.1 GO:0090543 Flemming body(GO:0090543)
0.1 3.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 1.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 25.0 GO:0016324 apical plasma membrane(GO:0016324)
0.1 0.5 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 5.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 2.0 GO:0031672 A band(GO:0031672)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 1.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 5.3 GO:0005901 caveola(GO:0005901)
0.1 1.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.9 GO:0017119 Golgi transport complex(GO:0017119)
0.1 10.9 GO:0030027 lamellipodium(GO:0030027)
0.1 2.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.7 GO:0001772 immunological synapse(GO:0001772)
0.0 2.0 GO:0000793 condensed chromosome(GO:0000793)
0.0 7.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 2.6 GO:0005844 polysome(GO:0005844)
0.0 0.6 GO:0000974 Prp19 complex(GO:0000974)
0.0 4.4 GO:0043195 terminal bouton(GO:0043195)
0.0 8.5 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 2.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.0 GO:0001741 XY body(GO:0001741)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.9 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 3.4 GO:0005814 centriole(GO:0005814)
0.0 1.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 2.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.5 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.0 6.6 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.8 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 4.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 25.2 GO:0005615 extracellular space(GO:0005615)
0.0 8.2 GO:0005929 cilium(GO:0005929)
0.0 0.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 3.9 GO:0009986 cell surface(GO:0009986)
0.0 0.6 GO:0000922 spindle pole(GO:0000922)
0.0 0.7 GO:0005913 cell-cell adherens junction(GO:0005913)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
9.0 27.1 GO:0002113 interleukin-33 binding(GO:0002113)
5.2 15.5 GO:0019202 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
3.6 10.8 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
2.3 6.9 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
2.2 8.6 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
1.9 13.4 GO:0004556 alpha-amylase activity(GO:0004556)
1.8 20.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
1.7 5.1 GO:0016748 succinyltransferase activity(GO:0016748)
1.6 9.7 GO:0004126 cytidine deaminase activity(GO:0004126)
1.5 8.8 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
1.4 5.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
1.3 9.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.2 8.7 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
1.1 3.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
1.1 8.5 GO:0004064 arylesterase activity(GO:0004064)
1.0 4.0 GO:0015057 thrombin receptor activity(GO:0015057)
1.0 6.0 GO:0061649 ubiquitinated histone binding(GO:0061649)
1.0 5.0 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.8 4.2 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.8 2.4 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.8 14.7 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.8 3.0 GO:0004074 biliverdin reductase activity(GO:0004074)
0.7 3.7 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.7 2.2 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.7 9.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.6 17.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.6 20.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.6 1.8 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.6 5.0 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.5 2.7 GO:0016726 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.5 12.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.5 2.5 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.5 7.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.5 2.9 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.5 4.3 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.5 6.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.5 3.6 GO:0001849 complement component C1q binding(GO:0001849)
0.4 1.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.4 6.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.4 4.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.4 2.8 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.4 3.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.4 24.3 GO:0004601 peroxidase activity(GO:0004601)
0.4 5.0 GO:0005522 profilin binding(GO:0005522)
0.4 1.8 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) L-lysine transmembrane transporter activity(GO:0015189)
0.4 6.4 GO:0035174 histone serine kinase activity(GO:0035174)
0.3 1.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 2.0 GO:0004977 melanocortin receptor activity(GO:0004977)
0.3 3.0 GO:1990446 U1 snRNP binding(GO:1990446)
0.3 1.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.3 9.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.3 3.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.3 2.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.3 2.4 GO:0016531 copper chaperone activity(GO:0016531)
0.3 1.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.3 9.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.3 5.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 1.1 GO:0004568 chitinase activity(GO:0004568)
0.3 2.1 GO:0009374 biotin binding(GO:0009374)
0.3 1.3 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2 2.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 1.0 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.2 6.7 GO:0005550 pheromone binding(GO:0005550)
0.2 0.7 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 5.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 2.6 GO:0051870 methotrexate binding(GO:0051870)
0.2 1.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 7.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 2.0 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 1.5 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.2 4.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 1.4 GO:0005499 vitamin D binding(GO:0005499)
0.2 1.0 GO:0031493 nucleosomal histone binding(GO:0031493)
0.2 2.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.2 0.7 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.2 1.2 GO:0000150 recombinase activity(GO:0000150)
0.2 1.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 1.0 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.2 8.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 8.5 GO:0042169 SH2 domain binding(GO:0042169)
0.2 0.7 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.2 2.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.2 1.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 0.6 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 1.9 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 6.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 7.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.0 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 3.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 2.8 GO:0042287 MHC protein binding(GO:0042287)
0.1 1.8 GO:0050700 CARD domain binding(GO:0050700)
0.1 3.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.6 GO:0034235 GPI anchor binding(GO:0034235)
0.1 3.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 1.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 9.7 GO:0005518 collagen binding(GO:0005518)
0.1 1.0 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.7 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 2.8 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 4.8 GO:0032452 histone demethylase activity(GO:0032452)
0.1 5.2 GO:0005109 frizzled binding(GO:0005109)
0.1 4.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 4.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.6 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 11.7 GO:0005179 hormone activity(GO:0005179)
0.1 0.9 GO:0034452 dynactin binding(GO:0034452)
0.1 0.7 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 1.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 3.4 GO:0005549 odorant binding(GO:0005549)
0.1 7.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 1.3 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 2.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 8.9 GO:0003774 motor activity(GO:0003774)
0.1 0.5 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 15.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 9.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 1.1 GO:0043495 adenylate cyclase binding(GO:0008179) protein anchor(GO:0043495)
0.1 0.6 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 4.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.8 GO:0048185 activin binding(GO:0048185)
0.1 0.4 GO:0089720 caspase binding(GO:0089720)
0.1 3.9 GO:0015485 cholesterol binding(GO:0015485)
0.1 4.9 GO:0003823 antigen binding(GO:0003823)
0.1 2.0 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 9.6 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 9.9 GO:0017124 SH3 domain binding(GO:0017124)
0.1 2.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 12.0 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 2.8 GO:0035064 methylated histone binding(GO:0035064)
0.1 12.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 4.6 GO:0005178 integrin binding(GO:0005178)
0.0 3.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 16.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 3.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.4 GO:0003924 GTPase activity(GO:0003924)
0.0 1.2 GO:0008009 chemokine activity(GO:0008009)
0.0 0.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 4.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 1.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 4.2 GO:0051015 actin filament binding(GO:0051015)
0.0 1.0 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 2.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.9 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 0.4 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 4.6 GO:0005525 GTP binding(GO:0005525)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 34.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.5 4.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.4 22.5 PID IL23 PATHWAY IL23-mediated signaling events
0.4 6.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 5.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.2 6.4 PID AURORA A PATHWAY Aurora A signaling
0.2 6.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 6.4 PID EPO PATHWAY EPO signaling pathway
0.2 4.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 8.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 7.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 2.2 PID IL27 PATHWAY IL27-mediated signaling events
0.1 3.7 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 5.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 4.0 ST GA12 PATHWAY G alpha 12 Pathway
0.1 5.8 PID BCR 5PATHWAY BCR signaling pathway
0.1 1.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 3.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 9.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 4.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 29.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 9.2 PID NOTCH PATHWAY Notch signaling pathway
0.1 20.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 2.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 3.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 3.9 PID PLK1 PATHWAY PLK1 signaling events
0.1 3.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 3.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 1.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 2.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 2.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 2.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 1.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 13.4 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 2.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.9 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.6 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 3.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 13.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.8 18.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.6 10.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.6 15.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.6 19.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.6 31.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.5 3.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.5 10.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.4 4.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.4 10.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.4 8.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.4 18.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.3 5.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 11.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 10.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 4.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 3.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 19.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 5.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 20.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 6.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 9.0 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.1 1.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 4.8 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 1.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 2.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 10.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 4.8 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.1 1.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.9 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 6.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 1.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 2.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 2.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.4 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 2.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.0 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME NEGATIVE REGULATION OF FGFR SIGNALING Genes involved in Negative regulation of FGFR signaling
0.0 0.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 2.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA