Motif ID: Dlx1

Z-value: 2.247


Transcription factors associated with Dlx1:

Gene SymbolEntrez IDGene Name
Dlx1 ENSMUSG00000041911.3 Dlx1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dlx1mm10_v2_chr2_+_71528657_715286830.421.1e-02Click!


Activity profile for motif Dlx1.

activity profile for motif Dlx1


Sorted Z-values histogram for motif Dlx1

Sorted Z-values for motif Dlx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Dlx1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_84988194 25.054 ENSMUST00000028466.5
Prg3
proteoglycan 3
chr19_-_34166037 23.701 ENSMUST00000025686.7
Ankrd22
ankyrin repeat domain 22
chr11_+_87793470 22.487 ENSMUST00000020779.4
Mpo
myeloperoxidase
chr14_+_80000292 19.076 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr1_+_131638306 17.672 ENSMUST00000073350.6
Ctse
cathepsin E
chr11_+_58918004 17.643 ENSMUST00000108818.3
ENSMUST00000020792.5
Btnl10

butyrophilin-like 10

chr16_+_36277145 15.526 ENSMUST00000042097.9
Stfa1
stefin A1
chr1_+_40439767 15.064 ENSMUST00000173514.1
Il1rl1
interleukin 1 receptor-like 1
chr17_+_40811089 14.705 ENSMUST00000024721.7
Rhag
Rhesus blood group-associated A glycoprotein
chr11_+_58917889 14.576 ENSMUST00000069941.6
Btnl10
butyrophilin-like 10
chr14_+_27000362 13.902 ENSMUST00000035433.8
Hesx1
homeobox gene expressed in ES cells
chr4_+_34893772 13.226 ENSMUST00000029975.3
ENSMUST00000135871.1
ENSMUST00000108130.1
Cga


glycoprotein hormones, alpha subunit


chr1_+_40439627 12.028 ENSMUST00000097772.3
Il1rl1
interleukin 1 receptor-like 1
chr1_-_132390301 11.907 ENSMUST00000132435.1
Tmcc2
transmembrane and coiled-coil domains 2
chr2_+_131491764 10.767 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
Smox






spermine oxidase






chr6_+_41354105 10.721 ENSMUST00000072103.5
Try10
trypsin 10
chr6_+_30541582 10.568 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr9_-_123678782 10.439 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr5_-_108749448 10.262 ENSMUST00000068946.7
Rnf212
ring finger protein 212
chr6_-_40999479 10.249 ENSMUST00000166306.1
Gm2663
predicted gene 2663
chr1_+_107535508 10.119 ENSMUST00000182198.1
Serpinb10
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
chr2_-_126500631 9.931 ENSMUST00000129187.1
Atp8b4
ATPase, class I, type 8B, member 4
chr3_-_75270073 9.789 ENSMUST00000039047.4
Serpini2
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr17_-_48432723 9.735 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr8_-_85380964 9.271 ENSMUST00000122452.1
Mylk3
myosin light chain kinase 3
chr5_+_90768511 9.254 ENSMUST00000031319.6
Ppbp
pro-platelet basic protein
chr12_+_109540979 9.083 ENSMUST00000129245.1
ENSMUST00000143836.1
ENSMUST00000124106.1
Meg3


maternally expressed 3


chr17_+_5799491 9.073 ENSMUST00000181484.1
3300005D01Rik
RIKEN cDNA 3300005D01 gene
chr7_-_119459266 9.040 ENSMUST00000033255.5
Gp2
glycoprotein 2 (zymogen granule membrane)
chr13_+_104229366 8.885 ENSMUST00000022227.6
Cenpk
centromere protein K
chr9_-_123678873 8.820 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr7_-_133702515 8.756 ENSMUST00000153698.1
Uros
uroporphyrinogen III synthase
chr14_+_32321987 8.689 ENSMUST00000022480.7
Ogdhl
oxoglutarate dehydrogenase-like
chr8_-_4779513 8.468 ENSMUST00000022945.7
Shcbp1
Shc SH2-domain binding protein 1
chr19_-_40588374 8.010 ENSMUST00000175932.1
ENSMUST00000176955.1
ENSMUST00000149476.2
Aldh18a1


aldehyde dehydrogenase 18 family, member A1


chr19_+_58759700 7.822 ENSMUST00000026081.3
Pnliprp2
pancreatic lipase-related protein 2
chr5_-_43981757 7.810 ENSMUST00000061299.7
Fgfbp1
fibroblast growth factor binding protein 1
chr1_-_93342734 7.809 ENSMUST00000027493.3
Pask
PAS domain containing serine/threonine kinase
chr8_+_94172618 7.687 ENSMUST00000034214.6
Mt2
metallothionein 2
chr3_-_113258837 7.640 ENSMUST00000098673.3
Amy2a5
amylase 2a5
chr16_-_75909272 7.627 ENSMUST00000114239.2
Samsn1
SAM domain, SH3 domain and nuclear localization signals, 1
chr3_-_20275659 7.591 ENSMUST00000011607.5
Cpb1
carboxypeptidase B1 (tissue)
chr15_+_44457522 7.484 ENSMUST00000166957.1
ENSMUST00000038336.5
Pkhd1l1

polycystic kidney and hepatic disease 1-like 1

chr19_-_40588338 7.473 ENSMUST00000176939.1
Aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr2_+_119047116 7.423 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr15_-_36879816 7.180 ENSMUST00000100713.2
Gm10384
predicted gene 10384
chr15_+_84232030 7.121 ENSMUST00000023072.6
Parvb
parvin, beta
chr11_+_83437678 6.886 ENSMUST00000037378.4
1700020L24Rik
RIKEN cDNA 1700020L24 gene
chr6_-_36811361 6.871 ENSMUST00000101534.1
Ptn
pleiotrophin
chr3_-_116253467 6.861 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr10_+_115817247 6.734 ENSMUST00000035563.7
ENSMUST00000080630.3
ENSMUST00000179196.1
Tspan8


tetraspanin 8


chr9_+_65890237 6.679 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chrX_+_150547375 6.650 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr17_-_35027909 6.584 ENSMUST00000040151.2
Sapcd1
suppressor APC domain containing 1
chr8_+_23411490 6.507 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr3_-_14778452 6.424 ENSMUST00000094365.4
Car1
carbonic anhydrase 1
chr11_+_69045640 6.399 ENSMUST00000108666.1
ENSMUST00000021277.5
Aurkb

aurora kinase B

chr14_+_118787894 6.216 ENSMUST00000047761.6
ENSMUST00000071546.7
Cldn10

claudin 10

chr9_-_58741543 6.173 ENSMUST00000098674.4
2410076I21Rik
RIKEN cDNA 2410076I21 gene
chr18_-_74207771 6.059 ENSMUST00000040188.8
ENSMUST00000177604.1
Ska1

spindle and kinetochore associated complex subunit 1

chr1_+_139454747 6.008 ENSMUST00000053364.8
ENSMUST00000097554.3
Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr9_-_95750335 5.982 ENSMUST00000053785.3
Trpc1
transient receptor potential cation channel, subfamily C, member 1
chr2_-_121235689 5.962 ENSMUST00000142400.1
Trp53bp1
transformation related protein 53 binding protein 1
chr6_+_123172893 5.913 ENSMUST00000088455.5
Clec4b2
C-type lectin domain family 4, member b2
chr12_-_101028983 5.863 ENSMUST00000068411.3
ENSMUST00000085096.3
Ccdc88c

coiled-coil domain containing 88C

chr11_-_106314494 5.839 ENSMUST00000167143.1
Cd79b
CD79B antigen
chr3_-_113291449 5.795 ENSMUST00000179568.1
Amy2a4
amylase 2a4
chr9_-_21963568 5.650 ENSMUST00000006397.5
Epor
erythropoietin receptor
chr7_+_43427622 5.638 ENSMUST00000177164.2
Lim2
lens intrinsic membrane protein 2
chr13_-_23551648 5.515 ENSMUST00000102971.1
Hist1h4f
histone cluster 1, H4f
chr16_+_32756336 5.494 ENSMUST00000135753.1
Muc4
mucin 4
chr11_+_11487671 5.482 ENSMUST00000020410.4
4930415F15Rik
RIKEN cDNA 4930415F15 gene
chr12_-_115790884 5.349 ENSMUST00000081809.5
Ighv1-73
immunoglobulin heavy variable 1-73
chr8_+_116921735 5.333 ENSMUST00000034205.4
Cenpn
centromere protein N
chr9_+_119063429 5.269 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr14_+_118854695 5.252 ENSMUST00000100314.3
Cldn10
claudin 10
chr8_-_62123106 5.147 ENSMUST00000034052.6
ENSMUST00000034054.7
Anxa10

annexin A10

chr6_-_129275360 5.145 ENSMUST00000032259.3
Cd69
CD69 antigen
chr1_-_126830632 5.132 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr10_+_119992916 5.085 ENSMUST00000105261.2
Grip1
glutamate receptor interacting protein 1
chr2_+_109280738 5.029 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr13_+_52596847 4.985 ENSMUST00000055087.6
Syk
spleen tyrosine kinase
chr12_-_55014329 4.973 ENSMUST00000172875.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr12_+_108605757 4.965 ENSMUST00000109854.2
Evl
Ena-vasodilator stimulated phosphoprotein
chrX_-_74246534 4.959 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr10_-_6980376 4.896 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chr10_-_62527438 4.880 ENSMUST00000160987.1
Srgn
serglycin
chr10_-_62527413 4.812 ENSMUST00000160643.1
Srgn
serglycin
chr13_+_44729535 4.800 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr3_-_106219477 4.741 ENSMUST00000082219.5
Chi3l4
chitinase 3-like 4
chr11_+_74082907 4.660 ENSMUST00000178159.1
Zfp616
zinc finger protein 616
chr7_-_25005895 4.635 ENSMUST00000102858.3
ENSMUST00000080882.6
Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr5_-_30945393 4.595 ENSMUST00000031051.6
Cgref1
cell growth regulator with EF hand domain 1
chr10_+_119992962 4.546 ENSMUST00000154238.1
Grip1
glutamate receptor interacting protein 1
chr13_+_23544052 4.444 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chrX_-_160906998 4.385 ENSMUST00000069417.5
Gja6
gap junction protein, alpha 6
chr6_-_122340525 4.351 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chrX_-_53114530 4.290 ENSMUST00000114843.2
Plac1
placental specific protein 1
chr2_+_85979312 4.278 ENSMUST00000170610.1
Olfr1030
olfactory receptor 1030
chr3_-_10254213 4.274 ENSMUST00000172126.1
ENSMUST00000117917.1
Fabp12

fatty acid binding protein 12

chr10_-_62422427 4.255 ENSMUST00000020277.8
Hkdc1
hexokinase domain containing 1
chr4_-_132075250 4.192 ENSMUST00000105970.1
ENSMUST00000105975.1
Epb4.1

erythrocyte protein band 4.1

chr5_+_141856692 4.154 ENSMUST00000074546.6
Sdk1
sidekick homolog 1 (chicken)
chr2_+_84839395 4.147 ENSMUST00000146816.1
ENSMUST00000028469.7
Slc43a1

solute carrier family 43, member 1

chr1_-_172895048 4.072 ENSMUST00000027824.5
Apcs
serum amyloid P-component
chr17_+_34914459 4.058 ENSMUST00000007249.8
Slc44a4
solute carrier family 44, member 4
chr6_-_122340499 4.048 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr13_-_95525239 4.031 ENSMUST00000022185.8
F2rl1
coagulation factor II (thrombin) receptor-like 1
chr2_-_160619971 4.028 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr15_-_34356421 4.006 ENSMUST00000179647.1
9430069I07Rik
RIKEN cDNA 9430069I07 gene
chr8_+_119700009 3.983 ENSMUST00000095171.3
Atp2c2
ATPase, Ca++ transporting, type 2C, member 2
chr2_+_119047129 3.980 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr14_+_61309753 3.939 ENSMUST00000055159.7
Arl11
ADP-ribosylation factor-like 11
chr3_-_27153861 3.938 ENSMUST00000108300.1
ENSMUST00000108298.2
Ect2

ect2 oncogene

chr6_-_50456085 3.870 ENSMUST00000146341.1
ENSMUST00000071728.4
Osbpl3

oxysterol binding protein-like 3

chr7_+_141746736 3.836 ENSMUST00000026590.8
Muc2
mucin 2
chr19_-_32196393 3.723 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr12_-_87444017 3.711 ENSMUST00000091090.4
2700073G19Rik
RIKEN cDNA 2700073G19 gene
chr9_-_57836706 3.706 ENSMUST00000164010.1
ENSMUST00000171444.1
ENSMUST00000098686.3
Arid3b


AT rich interactive domain 3B (BRIGHT-like)


chr10_-_76110956 3.688 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr17_-_26099257 3.686 ENSMUST00000053575.3
Gm8186
predicted gene 8186
chr14_-_104522615 3.662 ENSMUST00000022716.2
Rnf219
ring finger protein 219
chr19_+_55180799 3.655 ENSMUST00000025936.5
Tectb
tectorin beta
chr7_+_45621805 3.613 ENSMUST00000033100.4
Izumo1
izumo sperm-egg fusion 1
chr11_-_69895523 3.570 ENSMUST00000001631.6
Acap1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr2_+_4300462 3.568 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A
chr16_-_69863718 3.520 ENSMUST00000076500.7
Speer2
spermatogenesis associated glutamate (E)-rich protein 2
chr6_+_72097561 3.507 ENSMUST00000069994.4
ENSMUST00000114112.1
St3gal5

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

chr13_-_58354862 3.407 ENSMUST00000043605.5
Kif27
kinesin family member 27
chr19_-_55241236 3.399 ENSMUST00000069183.6
Gucy2g
guanylate cyclase 2g
chr3_+_146121655 3.352 ENSMUST00000039450.4
Mcoln3
mucolipin 3
chr6_+_122513643 3.306 ENSMUST00000118626.1
Mfap5
microfibrillar associated protein 5
chr2_-_73453918 3.295 ENSMUST00000102679.1
Wipf1
WAS/WASL interacting protein family, member 1
chrX_-_57338598 3.278 ENSMUST00000033468.4
ENSMUST00000114736.1
Arhgef6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

chr19_+_34100943 3.270 ENSMUST00000025685.6
Lipm
lipase, family member M
chr9_-_36726374 3.249 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
Chek1


checkpoint kinase 1


chr6_-_129876659 3.242 ENSMUST00000014687.4
ENSMUST00000122219.1
Klra17

killer cell lectin-like receptor, subfamily A, member 17

chr17_+_8236031 3.237 ENSMUST00000164411.2
Ccr6
chemokine (C-C motif) receptor 6
chr18_-_23981555 3.192 ENSMUST00000115829.1
Zscan30
zinc finger and SCAN domain containing 30
chr3_-_17230976 3.186 ENSMUST00000177874.1
Gm5283
predicted gene 5283
chr19_-_50678642 3.160 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr16_+_92478743 3.158 ENSMUST00000160494.1
2410124H12Rik
RIKEN cDNA 2410124H12 gene
chr9_-_21312255 3.151 ENSMUST00000115433.3
ENSMUST00000003397.7
Ap1m2

adaptor protein complex AP-1, mu 2 subunit

chr4_+_145585166 3.150 ENSMUST00000105739.1
ENSMUST00000119718.1
Gm13212

predicted gene 13212

chr10_-_129902726 3.135 ENSMUST00000071557.1
Olfr815
olfactory receptor 815
chr6_+_122513583 3.077 ENSMUST00000032210.7
ENSMUST00000148517.1
Mfap5

microfibrillar associated protein 5

chr19_-_11604828 3.025 ENSMUST00000025582.4
Ms4a6d
membrane-spanning 4-domains, subfamily A, member 6D
chr19_-_38043559 3.020 ENSMUST00000041475.8
ENSMUST00000172095.2
Myof

myoferlin

chr7_+_27452417 3.013 ENSMUST00000108357.1
Blvrb
biliverdin reductase B (flavin reductase (NADPH))
chr4_-_41464816 2.995 ENSMUST00000108055.2
ENSMUST00000154535.1
ENSMUST00000030148.5
Kif24


kinesin family member 24


chr2_-_85675173 2.992 ENSMUST00000099917.1
Olfr1006
olfactory receptor 1006
chr18_+_44104407 2.973 ENSMUST00000081271.5
Spink12
serine peptidase inhibitor, Kazal type 11
chr16_-_3908596 2.972 ENSMUST00000123235.2
1700037C18Rik
RIKEN cDNA 1700037C18 gene
chr18_+_37518341 2.960 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr19_+_53140430 2.957 ENSMUST00000111741.2
Add3
adducin 3 (gamma)
chr13_+_23555023 2.954 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d
chr12_+_102128718 2.949 ENSMUST00000159329.1
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr5_+_100845709 2.949 ENSMUST00000144623.1
Agpat9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr1_+_86021935 2.948 ENSMUST00000052854.6
ENSMUST00000125083.1
ENSMUST00000152501.1
ENSMUST00000113344.1
ENSMUST00000130504.1
ENSMUST00000153247.2
Spata3





spermatogenesis associated 3





chr2_-_113848655 2.932 ENSMUST00000102545.1
ENSMUST00000110948.1
Arhgap11a

Rho GTPase activating protein 11A

chr1_-_172027251 2.930 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr12_+_55124528 2.910 ENSMUST00000177768.1
Fam177a
family with sequence similarity 177, member A
chr2_-_164171113 2.906 ENSMUST00000045196.3
Kcns1
K+ voltage-gated channel, subfamily S, 1
chr9_-_90255927 2.891 ENSMUST00000144646.1
Tbc1d2b
TBC1 domain family, member 2B
chr3_-_130730375 2.857 ENSMUST00000079085.6
Rpl34
ribosomal protein L34
chr15_+_92344359 2.761 ENSMUST00000181901.1
Gm26760
predicted gene, 26760
chr10_+_80264942 2.760 ENSMUST00000105362.1
ENSMUST00000105361.3
Dazap1

DAZ associated protein 1

chr2_-_34913976 2.755 ENSMUST00000028232.3
Phf19
PHD finger protein 19
chr2_+_91650116 2.702 ENSMUST00000111331.2
Arhgap1
Rho GTPase activating protein 1
chr1_+_58210397 2.690 ENSMUST00000040442.5
Aox4
aldehyde oxidase 4
chrX_+_153139941 2.651 ENSMUST00000039720.4
ENSMUST00000144175.2
Rragb

Ras-related GTP binding B

chr4_+_12906838 2.649 ENSMUST00000143186.1
ENSMUST00000183345.1
Triqk

triple QxxK/R motif containing

chr13_+_23575753 2.643 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chr7_-_101869307 2.635 ENSMUST00000140584.1
ENSMUST00000134145.1
Folr1

folate receptor 1 (adult)

chr6_-_128275577 2.623 ENSMUST00000130454.1
Tead4
TEA domain family member 4
chr6_+_78370877 2.602 ENSMUST00000096904.3
Reg3b
regenerating islet-derived 3 beta
chr4_-_154928187 2.593 ENSMUST00000123514.1
Tnfrsf14
tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
chr4_+_101507947 2.564 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr17_-_47016956 2.543 ENSMUST00000165525.1
Gm16494
predicted gene 16494
chrY_+_90785442 2.510 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
Erdr1


erythroid differentiation regulator 1


chr5_+_19907502 2.506 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr13_-_62371936 2.498 ENSMUST00000107989.3
Gm3604
predicted gene 3604
chr10_-_88605017 2.464 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1

myosin binding protein C, slow-type

chrX_-_164250368 2.447 ENSMUST00000112263.1
Bmx
BMX non-receptor tyrosine kinase
chr2_-_120154600 2.447 ENSMUST00000028755.7
Ehd4
EH-domain containing 4
chrX_-_8074720 2.442 ENSMUST00000115636.3
ENSMUST00000115638.3
Suv39h1

suppressor of variegation 3-9 homolog 1 (Drosophila)

chr3_+_59952185 2.430 ENSMUST00000094227.3
Gm9696
predicted gene 9696
chr16_+_38346986 2.377 ENSMUST00000050273.8
ENSMUST00000120495.1
ENSMUST00000119704.1
Cox17

Gm21987
cytochrome c oxidase assembly protein 17

predicted gene 21987
chr17_-_31129602 2.376 ENSMUST00000024827.4
Tff3
trefoil factor 3, intestinal
chr10_-_51631458 2.364 ENSMUST00000020062.3
Gprc6a
G protein-coupled receptor, family C, group 6, member A
chr4_+_146654927 2.359 ENSMUST00000070932.3
Gm13248
predicted gene 13248
chr12_-_12940600 2.357 ENSMUST00000130990.1
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr2_+_69219971 2.354 ENSMUST00000005364.5
ENSMUST00000112317.2
G6pc2

glucose-6-phosphatase, catalytic, 2

chr8_-_21456560 2.344 ENSMUST00000110752.3
Gm7849
predicted gene 7849
chr9_-_62026788 2.339 ENSMUST00000034817.4
Paqr5
progestin and adipoQ receptor family member V
chr4_+_62525369 2.332 ENSMUST00000062145.1
4933430I17Rik
RIKEN cDNA 4933430I17 gene
chr12_+_84069325 2.307 ENSMUST00000046422.4
ENSMUST00000072505.4
Acot5

acyl-CoA thioesterase 5

chr19_+_23723279 2.295 ENSMUST00000067077.1
Gm9938
predicted gene 9938
chr7_+_84853573 2.287 ENSMUST00000078172.4
Olfr291
olfactory receptor 291
chr17_+_17316078 2.281 ENSMUST00000105311.3
Gm6712
predicted gene 6712

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 22.5 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
6.8 27.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
6.5 26.1 GO:0045575 basophil activation(GO:0045575)
5.2 15.5 GO:0006592 ornithine biosynthetic process(GO:0006592)
2.4 9.7 GO:0033380 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
2.4 2.4 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
2.4 7.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
2.2 8.8 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
2.2 6.5 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
2.1 6.4 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
2.1 6.4 GO:0036018 response to erythropoietin(GO:0036017) cellular response to erythropoietin(GO:0036018) erythropoietin-mediated signaling pathway(GO:0038162)
2.1 10.3 GO:0035822 meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
1.8 20.0 GO:0035524 proline transmembrane transport(GO:0035524)
1.7 6.9 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
1.7 6.9 GO:0061743 motor learning(GO:0061743)
1.7 5.1 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.7 5.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
1.6 14.7 GO:0015670 carbon dioxide transport(GO:0015670)
1.6 9.7 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
1.5 9.3 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
1.5 10.8 GO:0046208 spermine catabolic process(GO:0046208)
1.5 14.9 GO:0030916 otic vesicle formation(GO:0030916)
1.3 4.0 GO:1900135 positive regulation of eosinophil degranulation(GO:0043311) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949) positive regulation of renin secretion into blood stream(GO:1900135) positive regulation of eosinophil activation(GO:1902568)
1.2 5.0 GO:0042223 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425) cellular response to molecule of fungal origin(GO:0071226)
1.2 3.6 GO:0052203 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
1.2 6.0 GO:0051661 maintenance of centrosome location(GO:0051661)
1.2 7.2 GO:0002838 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
1.2 20.2 GO:0016540 protein autoprocessing(GO:0016540)
1.1 7.7 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
1.1 3.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
1.0 4.1 GO:1900620 acetylcholine biosynthetic process(GO:0008292) thiamine pyrophosphate transport(GO:0030974) acetate ester biosynthetic process(GO:1900620)
1.0 7.8 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.9 13.2 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.8 4.2 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.8 5.0 GO:0032439 endosome localization(GO:0032439)
0.8 3.2 GO:1902093 positive regulation of flagellated sperm motility(GO:1902093)
0.7 4.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.7 2.2 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.7 2.2 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.7 4.3 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.7 7.8 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.7 4.2 GO:0072592 oxygen metabolic process(GO:0072592)
0.7 2.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.6 1.8 GO:0015819 lysine transport(GO:0015819)
0.6 1.8 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.6 2.3 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.5 2.7 GO:0009115 xanthine catabolic process(GO:0009115)
0.5 1.6 GO:0015827 tryptophan transport(GO:0015827)
0.5 2.6 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.5 3.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.5 6.0 GO:0046541 saliva secretion(GO:0046541)
0.5 1.9 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.5 6.7 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.5 4.6 GO:0036376 sodium ion export from cell(GO:0036376)
0.5 9.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.4 7.6 GO:0019377 glycolipid catabolic process(GO:0019377)
0.4 4.9 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.4 4.8 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.4 2.6 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.4 2.6 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.4 1.3 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.4 1.3 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.4 3.7 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.4 6.0 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.4 2.8 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.4 1.2 GO:0045006 DNA deamination(GO:0045006)
0.4 5.0 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.4 3.0 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.4 5.9 GO:0002579 positive regulation of antigen processing and presentation(GO:0002579)
0.4 3.0 GO:0016584 nucleosome positioning(GO:0016584)
0.4 1.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.4 1.1 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.3 1.0 GO:0070543 response to linoleic acid(GO:0070543)
0.3 5.5 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.3 4.8 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 1.4 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.3 1.0 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.3 2.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.3 8.9 GO:0008340 determination of adult lifespan(GO:0008340)
0.3 1.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.3 16.9 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.3 3.6 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.3 3.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 2.6 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.3 2.9 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.3 3.8 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.3 0.6 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.3 1.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.3 0.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.3 2.4 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.3 1.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3 1.0 GO:1905154 negative regulation of membrane invagination(GO:1905154)
0.3 1.0 GO:1902340 negative regulation of chromosome condensation(GO:1902340)
0.3 0.8 GO:1905600 regulation of receptor-mediated endocytosis involved in cholesterol transport(GO:1905600) positive regulation of receptor-mediated endocytosis involved in cholesterol transport(GO:1905602)
0.2 1.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 7.6 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.2 0.5 GO:1900239 regulation of phenotypic switching(GO:1900239)
0.2 2.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2 3.0 GO:0001778 plasma membrane repair(GO:0001778)
0.2 6.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 9.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.2 1.4 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.2 0.7 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.2 3.9 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 0.7 GO:0061193 taste bud development(GO:0061193)
0.2 4.0 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.2 1.8 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.2 1.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.2 1.6 GO:0006265 DNA topological change(GO:0006265)
0.2 2.4 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2 0.4 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2 0.4 GO:0035739 T cell proliferation involved in immune response(GO:0002309) CD4-positive, alpha-beta T cell proliferation(GO:0035739)
0.2 5.3 GO:0034508 centromere complex assembly(GO:0034508)
0.2 0.8 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.2 1.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 0.9 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 11.8 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.2 2.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 5.7 GO:0019236 response to pheromone(GO:0019236)
0.2 4.1 GO:0072520 seminiferous tubule development(GO:0072520)
0.2 11.2 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.2 0.7 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.2 1.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 2.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 8.6 GO:0050819 negative regulation of coagulation(GO:0050819)
0.2 0.6 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 1.8 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.4 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 2.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 1.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 2.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 3.3 GO:0006907 pinocytosis(GO:0006907)
0.1 1.0 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.1 1.2 GO:0051013 microtubule severing(GO:0051013)
0.1 3.7 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 8.4 GO:0016574 histone ubiquitination(GO:0016574)
0.1 6.3 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 2.1 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 5.1 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 1.3 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 3.4 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.1 2.9 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 3.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 4.7 GO:0051693 actin filament capping(GO:0051693)
0.1 0.6 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 10.5 GO:0007586 digestion(GO:0007586)
0.1 5.8 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.0 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 2.3 GO:0097186 amelogenesis(GO:0097186)
0.1 2.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 1.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 3.4 GO:0021591 ventricular system development(GO:0021591)
0.1 0.2 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 4.1 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 3.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 1.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.0 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 10.1 GO:0031109 microtubule polymerization or depolymerization(GO:0031109)
0.1 1.2 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.1 4.7 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 2.0 GO:0030810 positive regulation of cyclic nucleotide biosynthetic process(GO:0030804) positive regulation of nucleotide biosynthetic process(GO:0030810) positive regulation of purine nucleotide biosynthetic process(GO:1900373)
0.1 7.3 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.1 3.4 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.1 5.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 2.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 1.3 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.1 1.1 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.3 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.1 0.4 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.1 2.2 GO:1901016 regulation of potassium ion transmembrane transporter activity(GO:1901016)
0.1 1.2 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 0.5 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1 2.5 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 0.7 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.1 0.1 GO:0140009 L-aspartate import across plasma membrane(GO:0140009) D-aspartate import across plasma membrane(GO:0140016)
0.0 1.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.9 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 2.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 12.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 4.2 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.7 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.3 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.6 GO:0071420 cellular response to histamine(GO:0071420)
0.0 2.2 GO:0007566 embryo implantation(GO:0007566)
0.0 2.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 4.6 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.9 GO:0050715 positive regulation of cytokine secretion(GO:0050715)
0.0 2.1 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 3.2 GO:0060998 regulation of dendritic spine development(GO:0060998)
0.0 0.9 GO:0031424 keratinization(GO:0031424)
0.0 1.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.2 GO:0007626 locomotory behavior(GO:0007626)
0.0 0.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.4 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 1.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 2.0 GO:0034101 erythrocyte homeostasis(GO:0034101)
0.0 1.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 2.2 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 1.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.8 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.3 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 0.1 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 1.6 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 2.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.0 GO:0061734 parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization(GO:0061734)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 19.1 GO:0042581 specific granule(GO:0042581)
1.5 10.8 GO:0019815 B cell receptor complex(GO:0019815)
1.4 22.5 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
1.3 5.1 GO:0060187 cell pole(GO:0060187)
1.2 5.0 GO:0008623 CHRAC(GO:0008623)
1.2 6.0 GO:0036449 microtubule minus-end(GO:0036449)
1.1 6.4 GO:0032133 chromosome passenger complex(GO:0032133)
1.0 5.0 GO:0031523 Myb complex(GO:0031523)
0.9 1.7 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.8 4.2 GO:0070826 paraferritin complex(GO:0070826)
0.8 5.0 GO:0097443 sorting endosome(GO:0097443)
0.8 3.9 GO:0097149 centralspindlin complex(GO:0097149)
0.7 20.1 GO:0042588 zymogen granule(GO:0042588)
0.7 5.0 GO:0005828 kinetochore microtubule(GO:0005828)
0.7 7.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.6 8.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.5 2.7 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.5 4.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.5 8.6 GO:0001527 microfibril(GO:0001527)
0.5 2.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.5 8.4 GO:0035102 PRC1 complex(GO:0035102)
0.5 1.8 GO:0120001 apical plasma membrane urothelial plaque(GO:0120001)
0.5 1.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.4 1.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.4 1.8 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.4 3.7 GO:0000138 Golgi trans cisterna(GO:0000138)
0.4 1.1 GO:0030312 external encapsulating structure(GO:0030312)
0.3 3.0 GO:0097524 sperm plasma membrane(GO:0097524)
0.3 5.3 GO:0019814 immunoglobulin complex(GO:0019814)
0.3 2.5 GO:0071438 invadopodium membrane(GO:0071438)
0.3 7.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 1.4 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.2 9.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 1.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 0.9 GO:0005594 collagen type IX trimer(GO:0005594)
0.2 4.0 GO:0031143 pseudopodium(GO:0031143)
0.2 1.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 5.5 GO:0031528 microvillus membrane(GO:0031528)
0.2 7.8 GO:0000786 nucleosome(GO:0000786)
0.2 0.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 4.4 GO:0005922 connexin complex(GO:0005922)
0.2 0.6 GO:0035841 new growing cell tip(GO:0035841)
0.1 1.3 GO:0000243 commitment complex(GO:0000243)
0.1 6.0 GO:0090734 site of double-strand break(GO:0035861) site of DNA damage(GO:0090734)
0.1 2.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 2.2 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.1 2.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.7 GO:0034709 methylosome(GO:0034709)
0.1 3.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.9 GO:0097422 tubular endosome(GO:0097422)
0.1 1.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.9 GO:0031932 TORC2 complex(GO:0031932)
0.1 20.0 GO:0005923 bicellular tight junction(GO:0005923)
0.1 5.9 GO:0043034 costamere(GO:0043034)
0.1 1.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 2.5 GO:0005859 muscle myosin complex(GO:0005859)
0.1 3.6 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 41.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 6.4 GO:0005871 kinesin complex(GO:0005871)
0.1 1.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 11.2 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 11.9 GO:0000776 kinetochore(GO:0000776)
0.1 10.8 GO:0072562 blood microparticle(GO:0072562)
0.1 0.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 1.1 GO:0090543 Flemming body(GO:0090543)
0.1 3.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 3.3 GO:0005884 actin filament(GO:0005884)
0.1 1.7 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.5 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 1.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 23.2 GO:0016324 apical plasma membrane(GO:0016324)
0.1 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.1 5.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 2.0 GO:0031672 A band(GO:0031672)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 1.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 5.3 GO:0005901 caveola(GO:0005901)
0.1 0.9 GO:0017119 Golgi transport complex(GO:0017119)
0.1 4.7 GO:0098793 presynapse(GO:0098793)
0.1 10.9 GO:0030027 lamellipodium(GO:0030027)
0.1 1.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 2.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834) GTPase complex(GO:1905360)
0.0 1.7 GO:0001772 immunological synapse(GO:0001772)
0.0 2.0 GO:0000793 condensed chromosome(GO:0000793)
0.0 7.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 2.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 8.5 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 2.6 GO:0005844 polysome(GO:0005844)
0.0 0.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.0 GO:0001741 XY body(GO:0001741)
0.0 1.1 GO:0030424 axon(GO:0030424)
0.0 2.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.9 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 2.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.6 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 3.0 GO:0043195 terminal bouton(GO:0043195)
0.0 1.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.5 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.0 6.6 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.8 GO:0031519 PcG protein complex(GO:0031519)
0.0 3.1 GO:0005813 centrosome(GO:0005813)
0.0 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.6 GO:0001533 cornified envelope(GO:0001533)
0.0 3.3 GO:0005769 early endosome(GO:0005769)
0.0 1.6 GO:0036064 ciliary basal body(GO:0036064)
0.0 2.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.5 GO:0032421 stereocilium(GO:0032420) stereocilium bundle(GO:0032421)
0.0 7.8 GO:0009986 cell surface(GO:0009986)
0.0 1.2 GO:0005874 microtubule(GO:0005874)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.8 27.1 GO:0002114 interleukin-33 binding(GO:0002113) interleukin-33 receptor activity(GO:0002114)
5.2 15.5 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
3.6 10.8 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
2.3 6.9 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
2.2 8.6 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
1.9 13.4 GO:0004556 alpha-amylase activity(GO:0004556)
1.8 20.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
1.7 5.1 GO:0016748 succinyltransferase activity(GO:0016748)
1.6 9.7 GO:0004126 cytidine deaminase activity(GO:0004126)
1.5 8.8 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
1.4 5.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
1.2 8.7 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
1.2 9.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.1 3.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
1.1 8.5 GO:0004064 arylesterase activity(GO:0004064)
1.0 4.0 GO:0015057 thrombin-activated receptor activity(GO:0015057)
1.0 6.0 GO:0061649 ubiquitin modification-dependent histone binding(GO:0061649)
1.0 5.0 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.8 4.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.8 2.4 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.8 14.7 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.8 3.0 GO:0004074 biliverdin reductase activity(GO:0004074)
0.7 3.7 GO:0033188 ceramide phosphoethanolamine synthase activity(GO:0002950) sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.7 2.2 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.7 9.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.6 20.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.6 1.8 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.5 2.7 GO:0016623 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.5 3.6 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.5 12.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.5 2.5 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.5 7.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.5 2.9 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.5 4.3 GO:0008865 fructokinase activity(GO:0008865)
0.5 17.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.4 1.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.4 5.0 GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity(GO:0004716)
0.4 2.8 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.4 3.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.4 5.0 GO:0005522 profilin binding(GO:0005522)
0.4 24.3 GO:0004601 peroxidase activity(GO:0004601)
0.4 1.8 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) L-lysine transmembrane transporter activity(GO:0015189)
0.4 0.7 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.4 6.4 GO:0035174 histone serine kinase activity(GO:0035174)
0.3 1.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 2.0 GO:0004977 melanocortin receptor activity(GO:0004977)
0.3 6.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 3.0 GO:1990446 U1 snRNP binding(GO:1990446)
0.3 0.7 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.3 4.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.3 1.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.3 9.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.3 1.3 GO:0004825 methionine-tRNA ligase activity(GO:0004825)
0.3 3.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.3 2.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.3 2.4 GO:0016531 copper chaperone activity(GO:0016531) cuprous ion binding(GO:1903136)
0.3 1.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.3 9.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.3 6.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.3 5.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 1.1 GO:0004568 chitinase activity(GO:0004568)
0.3 2.1 GO:0009374 biotin binding(GO:0009374)
0.2 2.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 1.0 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.2 5.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 2.6 GO:0051870 methotrexate binding(GO:0051870)
0.2 1.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 7.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 5.7 GO:0016503 pheromone receptor activity(GO:0016503)
0.2 1.5 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.2 1.0 GO:0031493 nucleosomal histone binding(GO:0031493)
0.2 2.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.2 0.7 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.2 1.2 GO:0000150 recombinase activity(GO:0000150)
0.2 1.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 1.4 GO:0005499 vitamin D binding(GO:0005499)
0.2 1.0 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.2 8.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 8.5 GO:0042169 SH2 domain binding(GO:0042169)
0.2 4.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 2.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.2 1.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 0.6 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 1.9 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 7.6 GO:0001784 phosphotyrosine residue binding(GO:0001784)
0.1 6.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 1.0 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 1.8 GO:0050700 CARD domain binding(GO:0050700)
0.1 2.0 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.6 GO:0034235 GPI anchor binding(GO:0034235)
0.1 3.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 2.8 GO:0042287 MHC protein binding(GO:0042287)
0.1 1.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 1.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 1.0 GO:0033691 sialic acid binding(GO:0033691)
0.1 9.7 GO:0005518 collagen binding(GO:0005518)
0.1 0.7 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 2.8 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 4.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.6 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 4.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 4.8 GO:0032452 histone demethylase activity(GO:0032452)
0.1 11.7 GO:0005179 hormone activity(GO:0005179)
0.1 4.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 5.2 GO:0005109 frizzled binding(GO:0005109)
0.1 0.9 GO:0034452 dynactin binding(GO:0034452)
0.1 7.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.7 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 1.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 4.8 GO:0003823 antigen binding(GO:0003823)
0.1 1.3 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 2.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.5 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 3.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 3.4 GO:0005549 odorant binding(GO:0005549)
0.1 8.9 GO:0003774 motor activity(GO:0003774)
0.1 6.1 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 1.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.6 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 4.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.8 GO:0048185 activin binding(GO:0048185)
0.1 0.4 GO:0089720 caspase binding(GO:0089720)
0.1 21.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 3.9 GO:0015485 cholesterol binding(GO:0015485)
0.1 2.0 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 2.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 9.9 GO:0017124 SH3 domain binding(GO:0017124)
0.1 9.6 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 0.8 GO:0102991 myristoyl-CoA hydrolase activity(GO:0102991)
0.1 3.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 2.8 GO:0140034 methylated histone binding(GO:0035064) methylation-dependent protein binding(GO:0140034)
0.0 12.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 4.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 16.6 GO:0045296 cadherin binding(GO:0045296)
0.0 4.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 3.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.2 GO:0008009 chemokine activity(GO:0008009)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 4.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 1.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 4.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.7 GO:0004629 phospholipase C activity(GO:0004629)
0.0 1.0 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.1 GO:0002135 CTP binding(GO:0002135)
0.0 0.6 GO:0098988 G-protein coupled glutamate receptor activity(GO:0098988)
0.0 1.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0042393 histone binding(GO:0042393)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 2.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.9 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 0.4 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 4.6 GO:0005525 GTP binding(GO:0005525)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.9 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.4 GO:0032947 protein complex scaffold activity(GO:0032947)
0.0 0.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 1.1 GO:0030674 protein binding, bridging(GO:0030674)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 34.7 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.5 4.6 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.4 22.5 PID_IL23_PATHWAY IL23-mediated signaling events
0.4 6.9 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.2 5.0 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.2 6.4 PID_AURORA_A_PATHWAY Aurora A signaling
0.2 6.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.2 6.4 PID_EPO_PATHWAY EPO signaling pathway
0.2 4.9 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 8.2 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.2 7.2 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.2 2.2 PID_IL27_PATHWAY IL27-mediated signaling events
0.1 3.7 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.1 5.3 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 4.0 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 5.8 PID_BCR_5PATHWAY BCR signaling pathway
0.1 1.8 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.1 3.5 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 9.3 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.1 4.2 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 29.9 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 9.2 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 20.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.3 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 2.2 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 2.4 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 3.5 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.1 3.9 PID_PLK1_PATHWAY PLK1 signaling events
0.1 3.0 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 3.6 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.1 1.2 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.1 2.5 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 2.2 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 2.9 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.2 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.1 2.7 PID_MTOR_4PATHWAY mTOR signaling pathway
0.1 1.6 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.7 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 13.4 NABA_MATRISOME_ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 2.4 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 1.1 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 0.5 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 0.9 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.8 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.6 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.6 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.9 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 3.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 13.2 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.8 18.4 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.6 10.8 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.6 15.5 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.6 19.5 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.6 31.6 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.5 3.2 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.5 10.2 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.4 4.3 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.4 10.4 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.4 8.1 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.4 18.2 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.3 5.1 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 11.2 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.2 10.8 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 4.1 REACTOME_AMYLOIDS Genes involved in Amyloids
0.2 3.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 19.8 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 5.0 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.2 20.0 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 6.0 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.8 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 9.0 REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.1 1.7 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 4.8 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 1.2 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 2.4 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.6 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.3 REACTOME_POL_SWITCHING Genes involved in Polymerase switching
0.1 10.3 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 4.8 REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY Genes involved in Costimulation by the CD28 family
0.1 1.3 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.9 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 6.1 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 1.3 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 1.4 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.1 2.6 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.9 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 1.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 2.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.4 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 2.5 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.8 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.0 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.6 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.6 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME_NEGATIVE_REGULATION_OF_FGFR_SIGNALING Genes involved in Negative regulation of FGFR signaling
0.0 0.8 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.9 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.1 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 2.4 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.4 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA