Motif ID: E2f2_E2f5

Z-value: 5.213

Transcription factors associated with E2f2_E2f5:

Gene SymbolEntrez IDGene Name
E2f2 ENSMUSG00000018983.9 E2f2
E2f5 ENSMUSG00000027552.8 E2f5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2f2mm10_v2_chr4_+_136172367_1361723950.961.0e-20Click!
E2f5mm10_v2_chr3_+_14578609_145786870.464.3e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of E2f2_E2f5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_136172367 80.616 ENSMUST00000061721.5
E2f2
E2F transcription factor 2
chr4_+_134864536 75.272 ENSMUST00000030627.7
Rhd
Rh blood group, D antigen
chr4_+_126556935 54.090 ENSMUST00000048391.8
Clspn
claspin
chr17_+_56304313 46.706 ENSMUST00000113035.1
ENSMUST00000113039.2
ENSMUST00000142387.1
Uhrf1


ubiquitin-like, containing PHD and RING finger domains, 1


chr4_+_126556994 45.172 ENSMUST00000147675.1
Clspn
claspin
chr15_-_55090422 44.944 ENSMUST00000110231.1
ENSMUST00000023059.6
Dscc1

defective in sister chromatid cohesion 1 homolog (S. cerevisiae)

chr12_+_24708241 40.944 ENSMUST00000020980.5
Rrm2
ribonucleotide reductase M2
chr7_-_6730412 40.200 ENSMUST00000051209.4
Peg3
paternally expressed 3
chr9_+_122951051 38.281 ENSMUST00000040717.5
Kif15
kinesin family member 15
chr10_-_69352886 36.786 ENSMUST00000119827.1
ENSMUST00000020099.5
Cdk1

cyclin-dependent kinase 1

chr8_+_75109528 36.735 ENSMUST00000164309.1
Mcm5
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr13_-_55329723 36.573 ENSMUST00000021941.7
Mxd3
Max dimerization protein 3
chr10_-_5805412 36.066 ENSMUST00000019907.7
Fbxo5
F-box protein 5
chr6_+_4747306 35.568 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
Peg10


paternally expressed 10


chr2_-_28621932 34.117 ENSMUST00000028156.7
ENSMUST00000164290.1
Gfi1b

growth factor independent 1B

chr15_-_58135047 31.847 ENSMUST00000038194.3
Atad2
ATPase family, AAA domain containing 2
chr6_-_88898664 31.712 ENSMUST00000058011.6
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr5_-_138171813 30.969 ENSMUST00000155902.1
ENSMUST00000148879.1
Mcm7

minichromosome maintenance deficient 7 (S. cerevisiae)

chrX_-_51205990 30.531 ENSMUST00000114876.2
Mbnl3
muscleblind-like 3 (Drosophila)
chrX_-_51205773 30.106 ENSMUST00000114875.1
Mbnl3
muscleblind-like 3 (Drosophila)
chr11_+_80089385 28.558 ENSMUST00000108239.1
ENSMUST00000017694.5
Atad5

ATPase family, AAA domain containing 5

chr10_-_21160925 27.755 ENSMUST00000020158.6
Myb
myeloblastosis oncogene
chr12_-_69228167 26.845 ENSMUST00000021359.5
Pole2
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr1_-_128359610 26.471 ENSMUST00000027601.4
Mcm6
minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
chr4_+_115000156 26.396 ENSMUST00000030490.6
Stil
Scl/Tal1 interrupting locus
chr2_+_72476159 26.373 ENSMUST00000102691.4
Cdca7
cell division cycle associated 7
chr4_+_115000174 26.187 ENSMUST00000129957.1
Stil
Scl/Tal1 interrupting locus
chr9_-_20952838 24.855 ENSMUST00000004202.9
Dnmt1
DNA methyltransferase (cytosine-5) 1
chr12_-_11265768 24.206 ENSMUST00000166117.1
Gen1
Gen homolog 1, endonuclease (Drosophila)
chr2_+_72476225 23.984 ENSMUST00000157019.1
Cdca7
cell division cycle associated 7
chr2_-_113848655 22.873 ENSMUST00000102545.1
ENSMUST00000110948.1
Arhgap11a

Rho GTPase activating protein 11A

chr17_+_56303396 22.847 ENSMUST00000113038.1
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr1_-_20820213 22.785 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr9_+_109875541 22.183 ENSMUST00000094324.3
Cdc25a
cell division cycle 25A
chr1_-_191575534 21.949 ENSMUST00000027933.5
Dtl
denticleless homolog (Drosophila)
chr5_-_138172383 21.210 ENSMUST00000000505.9
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr2_-_113848601 21.176 ENSMUST00000110949.2
Arhgap11a
Rho GTPase activating protein 11A
chr2_-_157204483 21.001 ENSMUST00000029170.7
Rbl1
retinoblastoma-like 1 (p107)
chr12_+_116405397 20.775 ENSMUST00000084828.3
Ncapg2
non-SMC condensin II complex, subunit G2
chr2_+_119112793 20.499 ENSMUST00000140939.1
ENSMUST00000028795.3
Rad51

RAD51 homolog

chr12_+_24708984 19.663 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr2_-_154569845 19.145 ENSMUST00000103145.4
E2f1
E2F transcription factor 1
chr15_+_102296256 19.089 ENSMUST00000064924.4
Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr15_-_9140374 19.050 ENSMUST00000096482.3
ENSMUST00000110585.2
Skp2

S-phase kinase-associated protein 2 (p45)

chr10_+_110745433 19.032 ENSMUST00000174857.1
ENSMUST00000073781.5
ENSMUST00000173471.1
ENSMUST00000173634.1
E2f7



E2F transcription factor 7



chr11_+_116532441 18.625 ENSMUST00000106386.1
ENSMUST00000145737.1
ENSMUST00000155102.1
ENSMUST00000063446.6
Sphk1



sphingosine kinase 1



chrX_+_20703906 18.352 ENSMUST00000033383.2
Usp11
ubiquitin specific peptidase 11
chr9_+_64281575 18.007 ENSMUST00000034964.6
Tipin
timeless interacting protein
chr12_-_4874341 17.898 ENSMUST00000137337.1
ENSMUST00000045921.7
Mfsd2b

major facilitator superfamily domain containing 2B

chr11_+_116533257 17.823 ENSMUST00000154034.1
Sphk1
sphingosine kinase 1
chr13_-_22042949 17.663 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr11_+_95010277 17.602 ENSMUST00000124735.1
Samd14
sterile alpha motif domain containing 14
chr13_-_24761861 17.202 ENSMUST00000006898.3
ENSMUST00000110382.2
Gmnn

geminin

chr16_-_15637277 16.776 ENSMUST00000023353.3
Mcm4
minichromosome maintenance deficient 4 homolog (S. cerevisiae)
chr9_+_44334685 16.337 ENSMUST00000052686.2
H2afx
H2A histone family, member X
chr14_-_20388822 16.023 ENSMUST00000022345.6
Dnajc9
DnaJ (Hsp40) homolog, subfamily C, member 9
chr15_-_79605084 15.828 ENSMUST00000023065.6
Dmc1
DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination
chr9_+_65890237 15.591 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr10_+_13090788 15.496 ENSMUST00000121646.1
ENSMUST00000121325.1
ENSMUST00000121766.1
Plagl1


pleiomorphic adenoma gene-like 1


chr8_-_53638945 15.339 ENSMUST00000047768.4
Neil3
nei like 3 (E. coli)
chr8_-_120589304 15.263 ENSMUST00000034278.5
Gins2
GINS complex subunit 2 (Psf2 homolog)
chr19_+_8723478 15.126 ENSMUST00000180819.1
ENSMUST00000181422.1
Snhg1

small nucleolar RNA host gene (non-protein coding) 1

chr10_-_60219260 15.084 ENSMUST00000135158.2
Chst3
carbohydrate (chondroitin 6/keratan) sulfotransferase 3
chr13_+_22043189 15.038 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr6_+_113531675 14.497 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr14_+_79451791 14.316 ENSMUST00000100359.1
Zbtbd6
kelch repeat and BTB (POZ) domain containing 6
chr1_-_86359455 14.171 ENSMUST00000027438.6
Ncl
nucleolin
chr7_-_44548733 14.053 ENSMUST00000145956.1
ENSMUST00000049343.8
Pold1

polymerase (DNA directed), delta 1, catalytic subunit

chr3_+_88532314 13.950 ENSMUST00000172699.1
Mex3a
mex3 homolog A (C. elegans)
chrX_-_93632113 13.549 ENSMUST00000006856.2
Pola1
polymerase (DNA directed), alpha 1
chr5_+_88764983 13.428 ENSMUST00000031311.9
Dck
deoxycytidine kinase
chr16_-_18811615 13.217 ENSMUST00000096990.3
Cdc45
cell division cycle 45
chr1_-_156474249 12.753 ENSMUST00000051396.6
Soat1
sterol O-acyltransferase 1
chr4_+_134468320 12.335 ENSMUST00000030636.4
ENSMUST00000127279.1
ENSMUST00000105867.1
Stmn1


stathmin 1


chr17_+_56303321 12.319 ENSMUST00000001258.8
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr5_+_143909964 12.137 ENSMUST00000148011.1
ENSMUST00000110709.3
Pms2

postmeiotic segregation increased 2 (S. cerevisiae)

chr4_+_11191354 12.090 ENSMUST00000170901.1
Ccne2
cyclin E2
chr1_+_175880775 11.852 ENSMUST00000039725.6
Exo1
exonuclease 1
chr11_+_98907801 11.821 ENSMUST00000092706.6
Cdc6
cell division cycle 6
chrX_-_139871637 11.473 ENSMUST00000033811.7
ENSMUST00000087401.5
Morc4

microrchidia 4

chr7_-_38107490 11.441 ENSMUST00000108023.3
Ccne1
cyclin E1
chr13_-_21753851 11.279 ENSMUST00000074752.2
Hist1h2ak
histone cluster 1, H2ak
chr13_-_24761440 11.255 ENSMUST00000176890.1
ENSMUST00000175689.1
Gmnn

geminin

chr2_+_150909565 11.134 ENSMUST00000028948.4
Gins1
GINS complex subunit 1 (Psf1 homolog)
chr4_-_133967953 11.124 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr17_+_25016343 11.103 ENSMUST00000024983.5
Ift140
intraflagellar transport 140
chr4_+_32615473 11.046 ENSMUST00000178925.1
ENSMUST00000029950.3
Casp8ap2

caspase 8 associated protein 2

chr2_+_103970115 10.972 ENSMUST00000111143.1
ENSMUST00000138815.1
Lmo2

LIM domain only 2

chr11_+_11686213 10.628 ENSMUST00000076700.4
ENSMUST00000048122.6
Ikzf1

IKAROS family zinc finger 1

chr17_+_23726336 10.570 ENSMUST00000024701.7
Pkmyt1
protein kinase, membrane associated tyrosine/threonine 1
chr9_-_39603635 10.566 ENSMUST00000119722.1
AW551984
expressed sequence AW551984
chr19_-_10203880 10.559 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chr7_+_13278778 10.522 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
Lig1


ligase I, DNA, ATP-dependent


chr9_-_21291124 10.502 ENSMUST00000086374.6
Cdkn2d
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr7_+_110122299 10.420 ENSMUST00000033326.8
Wee1
WEE 1 homolog 1 (S. pombe)
chr11_+_58948890 10.299 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chr2_-_154569720 10.268 ENSMUST00000000894.5
E2f1
E2F transcription factor 1
chr5_-_24030297 10.252 ENSMUST00000101513.2
Fam126a
family with sequence similarity 126, member A
chr4_-_136835843 10.196 ENSMUST00000105846.2
ENSMUST00000059287.7
ENSMUST00000105845.2
Ephb2


Eph receptor B2


chrX_-_150814265 10.176 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
Maged2


melanoma antigen, family D, 2


chr18_-_62179948 10.161 ENSMUST00000053640.3
Adrb2
adrenergic receptor, beta 2
chr13_-_21787218 10.089 ENSMUST00000091751.2
Hist1h2an
histone cluster 1, H2an
chr5_+_75574916 10.031 ENSMUST00000144270.1
ENSMUST00000005815.6
Kit

kit oncogene

chr4_-_44704006 10.001 ENSMUST00000146335.1
Pax5
paired box gene 5
chrX_-_8074720 9.984 ENSMUST00000115636.3
ENSMUST00000115638.3
Suv39h1

suppressor of variegation 3-9 homolog 1 (Drosophila)

chrX_+_50841434 9.857 ENSMUST00000114887.2
2610018G03Rik
RIKEN cDNA 2610018G03 gene
chr7_-_126396715 9.778 ENSMUST00000075671.4
Nfatc2ip
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein
chr2_+_103970221 9.746 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2

LIM domain only 2

chrX_+_42151002 9.515 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr6_-_47594967 9.509 ENSMUST00000081721.6
ENSMUST00000114618.1
ENSMUST00000114616.1
Ezh2


enhancer of zeste homolog 2 (Drosophila)


chr4_+_132768325 9.453 ENSMUST00000102561.4
Rpa2
replication protein A2
chr5_+_110286306 9.417 ENSMUST00000007296.5
ENSMUST00000112482.1
Pole

polymerase (DNA directed), epsilon

chr7_+_66109474 9.397 ENSMUST00000036372.6
Chsy1
chondroitin sulfate synthase 1
chr13_-_22035589 9.209 ENSMUST00000091742.4
Hist1h2ah
histone cluster 1, H2ah
chr15_+_82298943 9.075 ENSMUST00000023089.3
Wbp2nl
WBP2 N-terminal like
chr10_-_80577285 9.054 ENSMUST00000038558.8
Klf16
Kruppel-like factor 16
chr13_-_23745511 9.005 ENSMUST00000091752.2
Hist1h3c
histone cluster 1, H3c
chr3_+_127553462 8.728 ENSMUST00000043108.4
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr19_+_53600377 8.629 ENSMUST00000025930.9
Smc3
structural maintenance of chromosomes 3
chr18_+_10617768 8.597 ENSMUST00000002551.3
Snrpd1
small nuclear ribonucleoprotein D1
chr7_+_102441685 8.488 ENSMUST00000033283.9
Rrm1
ribonucleotide reductase M1
chr12_-_12941827 8.288 ENSMUST00000043396.7
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr10_+_11281583 8.248 ENSMUST00000070300.4
Fbxo30
F-box protein 30
chr2_-_132253227 8.171 ENSMUST00000028817.6
Pcna
proliferating cell nuclear antigen
chr7_-_19359477 7.955 ENSMUST00000047036.8
Cd3eap
CD3E antigen, epsilon polypeptide associated protein
chr9_-_72491939 7.954 ENSMUST00000185151.1
ENSMUST00000085358.5
ENSMUST00000184125.1
ENSMUST00000183574.1
ENSMUST00000184831.1
Tex9




testis expressed gene 9




chr7_-_100121512 7.904 ENSMUST00000032969.7
Pold3
polymerase (DNA-directed), delta 3, accessory subunit
chr4_-_11966368 7.898 ENSMUST00000056050.4
ENSMUST00000108299.1
ENSMUST00000108297.2
Pdp1


pyruvate dehyrogenase phosphatase catalytic subunit 1


chr18_+_56707725 7.806 ENSMUST00000025486.8
Lmnb1
lamin B1
chr3_-_95217690 7.791 ENSMUST00000107209.1
Gabpb2
GA repeat binding protein, beta 2
chr9_+_96196246 7.745 ENSMUST00000165120.2
ENSMUST00000034982.9
Tfdp2

transcription factor Dp 2

chr5_+_110839973 7.716 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr17_-_28486082 7.698 ENSMUST00000079413.3
Fkbp5
FK506 binding protein 5
chr17_-_23740301 7.632 ENSMUST00000024702.3
Paqr4
progestin and adipoQ receptor family member IV
chr13_-_21833575 7.623 ENSMUST00000081342.5
Hist1h2ap
histone cluster 1, H2ap
chr17_+_25016068 7.617 ENSMUST00000137386.1
Ift140
intraflagellar transport 140
chr9_+_103305156 7.617 ENSMUST00000035164.3
Topbp1
topoisomerase (DNA) II binding protein 1
chr3_-_95217877 7.463 ENSMUST00000136139.1
Gabpb2
GA repeat binding protein, beta 2
chrX_+_135839034 7.264 ENSMUST00000173804.1
ENSMUST00000113136.1
Gprasp2

G protein-coupled receptor associated sorting protein 2

chr2_-_34913976 7.260 ENSMUST00000028232.3
Phf19
PHD finger protein 19
chr6_-_4747157 7.227 ENSMUST00000090686.4
ENSMUST00000115579.1
ENSMUST00000115577.2
ENSMUST00000101677.3
ENSMUST00000004750.8
Sgce




sarcoglycan, epsilon




chr3_+_116594959 7.226 ENSMUST00000029571.8
Sass6
spindle assembly 6 homolog (C. elegans)
chr8_-_105707933 7.110 ENSMUST00000013299.9
Enkd1
enkurin domain containing 1
chr4_-_43046196 7.108 ENSMUST00000036462.5
Fam214b
family with sequence similarity 214, member B
chr7_-_48881596 7.078 ENSMUST00000119223.1
E2f8
E2F transcription factor 8
chr6_-_52183828 7.061 ENSMUST00000134831.1
Hoxa3
homeobox A3
chr6_-_148946146 6.951 ENSMUST00000132696.1
Fam60a
family with sequence similarity 60, member A
chrX_+_135885851 6.901 ENSMUST00000180025.1
ENSMUST00000068755.7
ENSMUST00000148374.1
Bhlhb9


basic helix-loop-helix domain containing, class B9


chrX_-_59134421 6.832 ENSMUST00000033473.5
Fgf13
fibroblast growth factor 13
chr18_-_64489042 6.705 ENSMUST00000025484.7
Fech
ferrochelatase
chr9_-_102354685 6.654 ENSMUST00000035129.7
ENSMUST00000085169.5
Ephb1

Eph receptor B1

chr9_-_58741543 6.630 ENSMUST00000098674.4
2410076I21Rik
RIKEN cDNA 2410076I21 gene
chr17_+_28801090 6.627 ENSMUST00000004985.9
Brpf3
bromodomain and PHD finger containing, 3
chr13_-_21783391 6.492 ENSMUST00000099704.3
Hist1h3i
histone cluster 1, H3i
chr9_-_36726374 6.480 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
Chek1


checkpoint kinase 1


chr9_+_13827708 6.386 ENSMUST00000059579.5
Fam76b
family with sequence similarity 76, member B
chr7_+_126781483 6.372 ENSMUST00000172352.1
ENSMUST00000094037.4
Tbx6

T-box 6

chr17_+_29490812 6.310 ENSMUST00000024811.6
Pim1
proviral integration site 1
chr19_-_53371766 6.218 ENSMUST00000086887.1
Gm10197
predicted gene 10197
chr16_-_20426322 6.170 ENSMUST00000115547.2
ENSMUST00000096199.4
Abcc5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chr10_+_128232065 6.153 ENSMUST00000055539.4
ENSMUST00000105244.1
ENSMUST00000105243.2
ENSMUST00000125289.1
ENSMUST00000105242.1
Timeless




timeless circadian clock 1




chr2_+_91650116 6.042 ENSMUST00000111331.2
Arhgap1
Rho GTPase activating protein 1
chr15_+_61985540 6.024 ENSMUST00000159327.1
ENSMUST00000167731.1
Myc

myelocytomatosis oncogene

chr5_+_57718021 5.994 ENSMUST00000094783.3
ENSMUST00000068110.7
Pcdh7

protocadherin 7

chr6_-_4747019 5.969 ENSMUST00000126151.1
ENSMUST00000133306.1
ENSMUST00000123907.1
Sgce


sarcoglycan, epsilon


chr12_+_55836365 5.943 ENSMUST00000059250.6
Brms1l
breast cancer metastasis-suppressor 1-like
chr5_+_114130386 5.925 ENSMUST00000031587.6
Ung
uracil DNA glycosylase
chr7_-_45395672 5.892 ENSMUST00000074575.7
Snrnp70
small nuclear ribonucleoprotein 70 (U1)
chr4_+_100776664 5.851 ENSMUST00000030257.8
ENSMUST00000097955.2
Cachd1

cache domain containing 1

chr15_+_61985377 5.841 ENSMUST00000161976.1
ENSMUST00000022971.7
Myc

myelocytomatosis oncogene

chr16_-_20425881 5.835 ENSMUST00000077867.3
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr4_-_132843111 5.790 ENSMUST00000105919.1
ENSMUST00000030702.7
Ppp1r8

protein phosphatase 1, regulatory (inhibitor) subunit 8

chr5_-_110839757 5.758 ENSMUST00000056937.5
Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chrX_+_42150672 5.732 ENSMUST00000069619.7
Stag2
stromal antigen 2
chr17_-_35046726 5.615 ENSMUST00000097338.4
Msh5
mutS homolog 5 (E. coli)
chr13_+_21716385 5.601 ENSMUST00000070124.3
Hist1h2ai
histone cluster 1, H2ai
chr3_-_95217741 5.582 ENSMUST00000107204.1
Gabpb2
GA repeat binding protein, beta 2
chr7_+_79392305 5.549 ENSMUST00000117227.1
ENSMUST00000118959.1
ENSMUST00000036865.6
Fanci


Fanconi anemia, complementation group I


chr8_+_95633500 5.411 ENSMUST00000034094.9
Gins3
GINS complex subunit 3 (Psf3 homolog)
chr5_-_136135989 5.268 ENSMUST00000150406.1
ENSMUST00000006301.4
Lrwd1

leucine-rich repeats and WD repeat domain containing 1

chr17_-_71475285 5.164 ENSMUST00000127430.1
Smchd1
SMC hinge domain containing 1
chr9_-_108452377 5.145 ENSMUST00000035232.7
Klhdc8b
kelch domain containing 8B
chr11_-_87404380 5.140 ENSMUST00000067692.6
Rad51c
RAD51 homolog C
chr2_+_91650169 5.005 ENSMUST00000090614.4
Arhgap1
Rho GTPase activating protein 1
chr4_-_93335510 4.977 ENSMUST00000066774.4
Tusc1
tumor suppressor candidate 1
chr9_-_13827029 4.941 ENSMUST00000148086.1
ENSMUST00000034398.5
Cep57

centrosomal protein 57

chr19_-_5964132 4.867 ENSMUST00000025752.7
ENSMUST00000165143.1
Pola2

polymerase (DNA directed), alpha 2

chr15_-_8444449 4.778 ENSMUST00000052965.6
Nipbl
Nipped-B homolog (Drosophila)
chr12_+_71016658 4.769 ENSMUST00000125125.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr12_+_112644828 4.758 ENSMUST00000021728.4
ENSMUST00000109755.3
Siva1

SIVA1, apoptosis-inducing factor

chr2_+_132816141 4.663 ENSMUST00000028831.8
ENSMUST00000066559.5
Mcm8

minichromosome maintenance deficient 8 (S. cerevisiae)

chr5_-_110839575 4.603 ENSMUST00000145318.1
Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr2_-_152398046 4.592 ENSMUST00000063332.8
ENSMUST00000182625.1
Sox12

SRY-box containing gene 12

chr4_-_133967893 4.541 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr13_-_47106176 4.506 ENSMUST00000021807.6
ENSMUST00000135278.1
Dek

DEK oncogene (DNA binding)

chrX_+_68678541 4.293 ENSMUST00000088546.5
Fmr1
fragile X mental retardation syndrome 1
chr9_-_106887000 4.281 ENSMUST00000055843.7
Rbm15b
RNA binding motif protein 15B
chr1_-_38129618 4.222 ENSMUST00000027251.6
Rev1
REV1 homolog (S. cerevisiae)
chr1_+_183297060 4.211 ENSMUST00000109166.2
Aida
axin interactor, dorsalization associated
chr7_-_48881032 4.206 ENSMUST00000058745.8
E2f8
E2F transcription factor 8

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
15.7 110.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
14.8 147.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
10.9 21.7 GO:0006272 leading strand elongation(GO:0006272)
10.1 30.3 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
9.7 106.9 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
9.0 36.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
9.0 44.9 GO:0034421 post-translational protein acetylation(GO:0034421)
7.8 23.5 GO:0045004 DNA replication proofreading(GO:0045004)
7.2 107.9 GO:0010216 maintenance of DNA methylation(GO:0010216)
7.1 7.1 GO:0010159 specification of animal organ position(GO:0010159)
6.1 36.8 GO:1905448 positive regulation of mitochondrial ATP synthesis coupled electron transport(GO:1905448)
6.1 36.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
5.8 75.3 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
5.3 57.9 GO:1902969 mitotic DNA replication(GO:1902969)
5.2 31.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
5.2 5.2 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
4.3 34.1 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
4.2 4.2 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
3.9 7.8 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
3.9 3.9 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
3.8 69.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
3.8 52.6 GO:0033504 floor plate development(GO:0033504)
3.7 21.9 GO:0019985 translesion synthesis(GO:0019985)
3.6 18.0 GO:0048478 replication fork protection(GO:0048478)
3.5 10.6 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
3.4 13.4 GO:0046125 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
3.3 10.0 GO:0036018 response to erythropoietin(GO:0036017) cellular response to erythropoietin(GO:0036018) erythropoietin-mediated signaling pathway(GO:0038162)
3.3 117.7 GO:0006270 DNA replication initiation(GO:0006270)
3.0 24.2 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
3.0 21.0 GO:0042148 strand invasion(GO:0042148)
3.0 11.9 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
2.7 31.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
2.5 10.2 GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure(GO:0002025)
2.5 39.7 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
2.4 24.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
2.3 7.0 GO:0099578 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
2.3 6.8 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
2.2 6.5 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
2.1 27.8 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
2.1 10.6 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
2.1 6.2 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
2.0 7.9 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
2.0 5.9 GO:0006285 base-excision repair, AP site formation(GO:0006285)
1.9 19.5 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
1.9 16.9 GO:0021631 optic nerve morphogenesis(GO:0021631)
1.8 11.0 GO:0032439 endosome localization(GO:0032439)
1.8 14.2 GO:2000232 regulation of rRNA processing(GO:2000232)
1.8 12.3 GO:0070494 regulation of thrombin-activated receptor signaling pathway(GO:0070494) negative regulation of thrombin-activated receptor signaling pathway(GO:0070495)
1.6 61.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
1.6 20.7 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
1.6 19.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
1.6 11.0 GO:0036337 Fas signaling pathway(GO:0036337)
1.5 4.4 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
1.5 10.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
1.4 14.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
1.4 20.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
1.3 10.5 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
1.3 3.8 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
1.3 3.8 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
1.3 10.2 GO:0070294 renal sodium ion absorption(GO:0070294)
1.3 3.8 GO:0006597 spermine biosynthetic process(GO:0006597)
1.3 6.3 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
1.3 16.3 GO:0000212 meiotic spindle organization(GO:0000212)
1.2 8.7 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
1.2 4.8 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
1.2 10.6 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
1.1 15.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
1.1 26.8 GO:0008156 negative regulation of DNA replication(GO:0008156)
1.1 5.3 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
1.0 6.8 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
1.0 4.8 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.9 8.3 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.9 10.0 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.9 22.2 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.9 65.6 GO:0006342 chromatin silencing(GO:0006342)
0.9 6.9 GO:0051026 chiasma assembly(GO:0051026)
0.8 2.5 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.8 10.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.8 6.4 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.8 3.8 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.8 4.5 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.7 24.7 GO:0006284 base-excision repair(GO:0006284)
0.7 7.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.7 6.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.7 4.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.6 15.7 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.6 4.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.6 8.0 GO:0007343 egg activation(GO:0007343)
0.6 2.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.6 2.9 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.6 3.5 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.6 4.0 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.6 2.3 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.5 1.6 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.5 1.6 GO:0019045 latent virus replication(GO:0019045) release from viral latency(GO:0019046) modulation by host of viral molecular function(GO:0044868) regulation of DNA strand elongation(GO:0060382)
0.5 1.5 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.5 35.7 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.5 4.8 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.5 3.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.5 1.4 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.5 1.8 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.4 9.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.4 3.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.4 8.0 GO:0009303 rRNA transcription(GO:0009303)
0.4 1.4 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.4 2.1 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.3 10.4 GO:0007099 centriole replication(GO:0007099)
0.3 4.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.3 2.4 GO:0007000 nucleolus organization(GO:0007000)
0.3 0.6 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.3 3.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.3 11.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.3 18.8 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.3 13.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.3 2.9 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.3 5.5 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.3 0.8 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.3 2.6 GO:0006020 inositol metabolic process(GO:0006020)
0.3 1.8 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.2 1.9 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 0.9 GO:1903984 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.2 9.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.2 0.7 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.2 23.7 GO:0006334 nucleosome assembly(GO:0006334)
0.2 1.1 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.2 1.9 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.2 4.9 GO:0034453 microtubule anchoring(GO:0034453)
0.2 1.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 1.9 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 0.8 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.2 0.5 GO:1904328 regulation of myofibroblast contraction(GO:1904328) invadopodium organization(GO:1905863) myofibroblast contraction(GO:1990764)
0.2 5.8 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.2 1.2 GO:0072697 protein localization to cell cortex(GO:0072697)
0.2 10.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 1.0 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.2 12.5 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.2 6.9 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.2 3.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 5.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 3.2 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 0.5 GO:0010286 heat acclimation(GO:0010286)
0.1 6.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 1.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 2.2 GO:0032098 regulation of appetite(GO:0032098)
0.1 0.8 GO:0010793 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.1 2.9 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 1.2 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422)
0.1 1.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 1.5 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.1 2.1 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 5.5 GO:0019228 neuronal action potential(GO:0019228)
0.1 0.7 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.1 0.2 GO:0036228 protein localization to nuclear inner membrane(GO:0036228)
0.1 3.1 GO:0048520 positive regulation of behavior(GO:0048520)
0.1 9.2 GO:0016579 protein deubiquitination(GO:0016579)
0.1 1.7 GO:0021511 spinal cord patterning(GO:0021511)
0.1 3.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 1.0 GO:0042407 cristae formation(GO:0042407)
0.1 3.4 GO:0016925 protein sumoylation(GO:0016925)
0.1 1.9 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 2.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.7 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.7 GO:1904251 regulation of bile acid metabolic process(GO:1904251)
0.1 3.2 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.1 7.1 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 1.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 3.6 GO:0048477 oogenesis(GO:0048477)
0.0 3.0 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 1.9 GO:0031076 embryonic camera-type eye development(GO:0031076)
0.0 3.2 GO:0051225 spindle assembly(GO:0051225)
0.0 21.7 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.5 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.5 GO:0048148 behavioral response to cocaine(GO:0048148)
0.0 2.6 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 11.2 GO:0007018 microtubule-based movement(GO:0007018)
0.0 3.2 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.8 GO:0001541 ovarian follicle development(GO:0001541)
0.0 1.6 GO:0031175 neuron projection development(GO:0031175)
0.0 4.0 GO:0048511 rhythmic process(GO:0048511)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.5 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.9 GO:0021510 spinal cord development(GO:0021510)
0.0 1.1 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 1.7 GO:0022604 regulation of cell morphogenesis(GO:0022604)
0.0 1.0 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.3 GO:0000470 maturation of LSU-rRNA(GO:0000470)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
13.8 69.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
7.1 35.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
6.4 44.5 GO:0031298 replication fork protection complex(GO:0031298)
5.9 29.4 GO:0035189 Rb-E2F complex(GO:0035189)
5.1 246.3 GO:0042555 MCM complex(GO:0042555) MCM core complex(GO:0097373)
5.0 44.9 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
4.2 134.7 GO:0005657 replication fork(GO:0005657)
4.0 12.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
2.8 14.2 GO:0001651 dense fibrillar component(GO:0001651)
2.6 10.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
2.6 10.4 GO:0032389 MutLalpha complex(GO:0032389)
2.1 18.7 GO:0030991 intraciliary transport particle A(GO:0030991)
2.1 20.8 GO:0000796 condensin complex(GO:0000796)
2.0 10.0 GO:0033553 rDNA heterochromatin(GO:0033553)
1.9 5.6 GO:0035061 interchromatin granule(GO:0035061)
1.8 11.0 GO:0097443 sorting endosome(GO:0097443)
1.8 7.0 GO:1902737 viral replication complex(GO:0019034) dendritic filopodium(GO:1902737)
1.8 5.3 GO:0031933 telomeric heterochromatin(GO:0031933)
1.7 8.6 GO:0034715 pICln-Sm protein complex(GO:0034715)
1.6 21.9 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
1.4 8.6 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
1.3 19.8 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
1.3 7.6 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
1.2 7.2 GO:0098536 deuterosome(GO:0098536)
1.1 7.8 GO:0005638 lamin filament(GO:0005638)
1.0 5.2 GO:0001740 Barr body(GO:0001740)
1.0 53.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.9 2.8 GO:0005683 U7 snRNP(GO:0005683)
0.9 9.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.8 21.6 GO:0090734 site of double-strand break(GO:0035861) site of DNA damage(GO:0090734)
0.8 19.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.7 6.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.7 2.1 GO:0036284 tubulobulbar complex(GO:0036284)
0.7 5.9 GO:0000243 commitment complex(GO:0000243)
0.6 12.9 GO:0070822 Sin3-type complex(GO:0070822)
0.6 9.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.6 7.6 GO:0001673 male germ cell nucleus(GO:0001673)
0.6 40.3 GO:0044815 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.6 120.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.5 34.1 GO:0005871 kinesin complex(GO:0005871)
0.5 8.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.5 1.5 GO:0031251 PAN complex(GO:0031251)
0.5 2.7 GO:0044530 supraspliceosomal complex(GO:0044530)
0.4 11.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.4 1.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.4 3.2 GO:0070652 HAUS complex(GO:0070652)
0.4 33.6 GO:0005776 autophagosome(GO:0005776)
0.4 10.7 GO:0051233 spindle midzone(GO:0051233)
0.4 6.7 GO:0032433 filopodium tip(GO:0032433)
0.3 3.1 GO:0000801 central element(GO:0000801)
0.3 4.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.3 35.5 GO:0000781 chromosome, telomeric region(GO:0000781)
0.3 29.5 GO:0016363 nuclear matrix(GO:0016363)
0.3 1.2 GO:0034709 methylosome(GO:0034709)
0.3 2.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.3 20.1 GO:0072686 mitotic spindle(GO:0072686)
0.3 1.4 GO:0000791 euchromatin(GO:0000791)
0.3 3.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.2 0.5 GO:0061851 leading edge of lamellipodium(GO:0061851)
0.2 3.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 15.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 62.6 GO:0005667 transcription factor complex(GO:0005667)
0.2 27.2 GO:0005819 spindle(GO:0005819)
0.2 8.1 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 4.5 GO:0032993 protein-DNA complex(GO:0032993)
0.2 2.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 7.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 3.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 10.0 GO:0042629 mast cell granule(GO:0042629)
0.1 3.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 55.3 GO:0005813 centrosome(GO:0005813)
0.1 6.9 GO:0099086 synaptonemal complex(GO:0000795) synaptonemal structure(GO:0099086)
0.1 6.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.9 GO:0097470 ribbon synapse(GO:0097470) synaptic ribbon(GO:0098681)
0.1 2.9 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 7.5 GO:0016605 PML body(GO:0016605)
0.1 1.0 GO:0061617 MICOS complex(GO:0061617)
0.1 0.5 GO:0001652 granular component(GO:0001652)
0.1 2.9 GO:0090544 BAF-type complex(GO:0090544)
0.1 113.6 GO:0005694 chromosome(GO:0005694)
0.1 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 6.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 2.4 GO:0015030 Cajal body(GO:0015030)
0.1 1.3 GO:0043194 axon initial segment(GO:0043194)
0.1 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 30.9 GO:0030424 axon(GO:0030424)
0.1 2.9 GO:0043204 perikaryon(GO:0043204)
0.0 2.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 57.3 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 236.0 GO:0005634 nucleus(GO:0005634)
0.0 4.1 GO:0005925 focal adhesion(GO:0005925)
0.0 0.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.6 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
16.5 99.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
13.8 69.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
13.6 81.9 GO:0031493 nucleosomal histone binding(GO:0031493)
7.2 28.9 GO:0071987 WD40-repeat domain binding(GO:0071987)
6.6 26.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
5.9 41.5 GO:0000150 recombinase activity(GO:0000150)
5.6 22.4 GO:0048256 flap endonuclease activity(GO:0048256)
5.2 36.4 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
5.0 79.7 GO:0003688 DNA replication origin binding(GO:0003688)
4.1 44.9 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
4.0 24.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
4.0 36.1 GO:1990948 ubiquitin ligase inhibitor activity(GO:1990948)
3.4 13.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
3.1 9.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
3.1 24.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
3.1 15.3 GO:0000405 bubble DNA binding(GO:0000405)
3.0 15.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
3.0 18.0 GO:0044547 DNA topoisomerase binding(GO:0044547)
2.7 8.2 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
2.6 95.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
2.5 10.2 GO:0031711 beta-adrenergic receptor activity(GO:0004939) bradykinin receptor binding(GO:0031711)
2.4 75.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
2.4 16.9 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
2.3 67.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
2.3 6.9 GO:0030983 mismatched DNA binding(GO:0030983)
2.2 6.7 GO:0030350 iron-responsive element binding(GO:0030350)
2.2 6.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
2.0 36.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
2.0 10.0 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
2.0 7.9 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.9 17.3 GO:1990446 U1 snRNP binding(GO:1990446)
1.7 13.9 GO:0032404 mismatch repair complex binding(GO:0032404)
1.7 12.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
1.6 11.0 GO:0032184 SUMO polymer binding(GO:0032184)
1.5 5.9 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
1.3 3.8 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
1.2 4.7 GO:0036033 mediator complex binding(GO:0036033)
1.2 7.0 GO:0033592 RNA strand annealing activity(GO:0033592)
1.2 10.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
1.2 36.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
1.0 9.3 GO:0098505 single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.9 3.8 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.8 10.0 GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity(GO:0004716)
0.8 81.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.8 9.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.8 2.4 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.8 20.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.7 5.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.7 1.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.6 18.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.6 1.8 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.5 32.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.5 156.2 GO:0001047 core promoter binding(GO:0001047)
0.5 1.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.5 3.8 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.5 6.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.4 15.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.4 6.3 GO:0031386 protein tag(GO:0031386)
0.4 1.6 GO:0001069 regulatory region RNA binding(GO:0001069)
0.4 7.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4 2.3 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.3 34.1 GO:0003777 microtubule motor activity(GO:0003777)
0.3 7.1 GO:0071837 HMG box domain binding(GO:0071837)
0.3 2.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.3 30.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.3 1.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.3 10.4 GO:0001671 ATPase activator activity(GO:0001671)
0.3 2.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3 9.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.2 1.9 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 5.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.2 0.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 38.6 GO:0042393 histone binding(GO:0042393)
0.2 0.2 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.2 45.4 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.2 1.0 GO:0051425 PTB domain binding(GO:0051425)
0.2 9.1 GO:0050699 WW domain binding(GO:0050699)
0.2 20.6 GO:0051087 chaperone binding(GO:0051087)
0.2 2.4 GO:0031996 thioesterase binding(GO:0031996)
0.2 10.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 1.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 0.6 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 4.1 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 4.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 6.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.7 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 1.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 31.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 7.8 GO:0001540 amyloid-beta binding(GO:0001540)
0.1 14.5 GO:0004386 helicase activity(GO:0004386)
0.1 1.1 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.1 40.6 GO:0005096 GTPase activator activity(GO:0005096)
0.1 1.5 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 3.9 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 2.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.7 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 12.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 2.7 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 10.7 GO:0008301 DNA binding, bending(GO:0008301)
0.1 30.7 GO:0016887 ATPase activity(GO:0016887)
0.1 2.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.9 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 5.3 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.3 GO:0031402 sodium ion binding(GO:0031402)
0.1 3.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 2.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 14.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 34.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 4.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 2.5 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 3.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 12.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.7 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 1.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 1.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 3.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 4.8 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 1.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 4.2 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.8 GO:0031593 polyubiquitin modification-dependent protein binding(GO:0031593)
0.0 2.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.9 GO:0008134 transcription factor binding(GO:0008134)
0.0 6.1 GO:0044212 transcription regulatory region DNA binding(GO:0044212)
0.0 1.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 4.6 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 10.5 GO:0008270 zinc ion binding(GO:0008270)
0.0 5.3 GO:0003677 DNA binding(GO:0003677)
0.0 1.5 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.4 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 75.9 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
8.3 133.6 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
6.0 271.2 PID_ATR_PATHWAY ATR signaling pathway
1.9 158.5 PID_E2F_PATHWAY E2F transcription factor network
1.5 52.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
1.3 36.4 PID_S1P_S1P1_PATHWAY S1P1 pathway
1.0 26.8 PID_FOXM1_PATHWAY FOXM1 transcription factor network
1.0 48.5 PID_PLK1_PATHWAY PLK1 signaling events
0.9 95.7 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.9 11.0 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.9 12.8 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.7 21.0 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.7 27.8 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.5 8.2 PID_BARD1_PATHWAY BARD1 signaling events
0.4 28.8 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.4 12.3 PID_AURORA_B_PATHWAY Aurora B signaling
0.4 10.2 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.3 29.9 PID_CMYB_PATHWAY C-MYB transcription factor network
0.3 13.2 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.2 6.7 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 3.1 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 3.8 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 7.8 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 7.6 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.1 3.9 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 4.1 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.1 4.4 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 6.7 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 7.7 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.1 1.8 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 3.2 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 3.3 PID_P53_REGULATION_PATHWAY p53 pathway
0.1 2.4 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 2.1 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 1.5 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 2.4 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.9 PID_P73PATHWAY p73 transcription factor network
0.0 1.0 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.5 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.4 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
14.4 230.9 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
12.5 224.5 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
11.5 80.6 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
5.7 28.5 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
5.3 10.6 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
5.0 69.4 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
3.8 15.4 REACTOME_LAGGING_STRAND_SYNTHESIS Genes involved in Lagging Strand Synthesis
3.1 36.8 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
2.7 24.6 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
2.4 14.5 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
1.9 32.0 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
1.4 38.3 REACTOME_KINESINS Genes involved in Kinesins
1.2 24.5 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
1.1 52.3 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
1.1 10.6 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
1.0 58.9 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
1.0 29.6 REACTOME_G1_PHASE Genes involved in G1 Phase
0.7 12.2 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.7 13.4 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.6 7.9 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4 13.8 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.4 10.0 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.4 5.7 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.4 8.5 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.4 4.2 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.3 13.6 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.3 6.7 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 15.6 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.3 57.2 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.3 9.1 REACTOME_RNA_POL_I_TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.2 9.3 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 23.5 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 3.8 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.2 2.1 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.2 10.4 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.2 4.1 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 5.5 REACTOME_CHROMOSOME_MAINTENANCE Genes involved in Chromosome Maintenance
0.1 4.4 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 3.1 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 2.5 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 3.0 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.9 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.5 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.4 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.9 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.5 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.6 REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 2.2 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors