Motif ID: Elf3

Z-value: 1.188


Transcription factors associated with Elf3:

Gene SymbolEntrez IDGene Name
Elf3 ENSMUSG00000003051.7 Elf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Elf3mm10_v2_chr1_-_135258449_1352584720.651.6e-05Click!


Activity profile for motif Elf3.

activity profile for motif Elf3


Sorted Z-values histogram for motif Elf3

Sorted Z-values for motif Elf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Elf3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_142666816 15.256 ENSMUST00000105935.1
Igf2
insulin-like growth factor 2
chr2_-_28084877 14.610 ENSMUST00000028179.8
ENSMUST00000117486.1
ENSMUST00000135472.1
Fcnb


ficolin B


chr8_+_72761868 13.205 ENSMUST00000058099.8
F2rl3
coagulation factor II (thrombin) receptor-like 3
chr14_+_80000292 9.533 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr17_+_29135056 8.639 ENSMUST00000087942.4
Rab44
RAB44, member RAS oncogene family
chr11_+_87793470 7.658 ENSMUST00000020779.4
Mpo
myeloperoxidase
chr16_+_17980565 7.483 ENSMUST00000075371.3
Vpreb2
pre-B lymphocyte gene 2
chr11_+_87793722 7.331 ENSMUST00000143021.2
Mpo
myeloperoxidase
chr11_+_115887601 7.140 ENSMUST00000167507.2
Myo15b
myosin XVB
chr12_+_109544498 6.991 ENSMUST00000126289.1
Meg3
maternally expressed 3
chr5_-_43981757 6.916 ENSMUST00000061299.7
Fgfbp1
fibroblast growth factor binding protein 1
chrX_-_88760312 6.171 ENSMUST00000182943.1
Gm27000
predicted gene, 27000
chr15_-_103255433 5.767 ENSMUST00000075192.6
Nfe2
nuclear factor, erythroid derived 2
chr19_-_17356631 5.717 ENSMUST00000174236.1
Gcnt1
glucosaminyl (N-acetyl) transferase 1, core 2
chr1_-_128592284 5.397 ENSMUST00000052172.6
ENSMUST00000142893.1
Cxcr4

chemokine (C-X-C motif) receptor 4

chr17_+_25471564 5.193 ENSMUST00000025002.1
Tekt4
tektin 4
chr17_+_31208049 5.042 ENSMUST00000173776.1
Ubash3a
ubiquitin associated and SH3 domain containing, A
chr7_+_24777172 4.807 ENSMUST00000038069.7
Ceacam10
carcinoembryonic antigen-related cell adhesion molecule 10
chr5_+_115845229 4.621 ENSMUST00000137952.1
ENSMUST00000148245.1
Cit

citron

chr11_-_97996171 4.532 ENSMUST00000042971.9
Arl5c
ADP-ribosylation factor-like 5C
chr17_+_35049966 4.450 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chrX_-_135210672 4.252 ENSMUST00000033783.1
Tceal6
transcription elongation factor A (SII)-like 6
chr10_-_6980376 4.073 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chr11_-_6520894 4.048 ENSMUST00000003459.3
Myo1g
myosin IG
chr10_+_79927039 4.029 ENSMUST00000019708.5
ENSMUST00000105377.1
Arid3a

AT rich interactive domain 3A (BRIGHT-like)

chr12_-_65172560 4.007 ENSMUST00000052201.8
Mis18bp1
MIS18 binding protein 1
chr1_-_193201435 3.921 ENSMUST00000043550.4
Traf3ip3
TRAF3 interacting protein 3
chr3_+_84666192 3.749 ENSMUST00000107682.1
Tmem154
transmembrane protein 154
chr3_+_103832562 3.714 ENSMUST00000062945.5
Bcl2l15
BCLl2-like 15
chr7_+_131032061 3.689 ENSMUST00000084509.3
Dmbt1
deleted in malignant brain tumors 1
chr8_+_72189613 3.634 ENSMUST00000072097.6
Hsh2d
hematopoietic SH2 domain containing
chr1_+_136467958 3.530 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr6_+_60944472 3.398 ENSMUST00000129603.1
Mmrn1
multimerin 1
chr6_-_129917650 3.288 ENSMUST00000118060.1
Klra5
killer cell lectin-like receptor, subfamily A, member 5
chrX_-_8090442 3.284 ENSMUST00000033505.6
Was
Wiskott-Aldrich syndrome homolog (human)
chr7_-_3677509 3.281 ENSMUST00000038743.8
Tmc4
transmembrane channel-like gene family 4
chr2_+_164940742 3.174 ENSMUST00000137626.1
Mmp9
matrix metallopeptidase 9
chr10_-_30655859 3.108 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr9_-_66919646 3.097 ENSMUST00000041139.7
Rab8b
RAB8B, member RAS oncogene family
chr1_-_87101590 3.079 ENSMUST00000113270.2
Alpi
alkaline phosphatase, intestinal
chr1_+_135799833 3.077 ENSMUST00000148201.1
Tnni1
troponin I, skeletal, slow 1
chr1_+_170277376 3.071 ENSMUST00000179976.1
Sh2d1b1
SH2 domain protein 1B1
chr2_+_131491958 3.069 ENSMUST00000110181.1
ENSMUST00000110180.1
Smox

spermine oxidase

chr3_-_15332285 2.981 ENSMUST00000108361.1
Gm9733
predicted gene 9733
chr3_-_51396528 2.947 ENSMUST00000038154.5
Mgarp
mitochondria localized glutamic acid rich protein
chr2_+_131491764 2.922 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
Smox






spermine oxidase






chrX_+_48146436 2.852 ENSMUST00000033427.6
Sash3
SAM and SH3 domain containing 3
chr2_-_32083783 2.716 ENSMUST00000056406.6
Fam78a
family with sequence similarity 78, member A
chr17_+_71019503 2.677 ENSMUST00000024847.7
Myom1
myomesin 1
chr7_+_30776394 2.668 ENSMUST00000041703.7
Dmkn
dermokine
chr2_+_101624734 2.605 ENSMUST00000111227.1
Rag2
recombination activating gene 2
chr8_-_88636117 2.603 ENSMUST00000034087.7
Snx20
sorting nexin 20
chr3_-_51396502 2.543 ENSMUST00000108046.1
Mgarp
mitochondria localized glutamic acid rich protein
chr3_-_51396716 2.511 ENSMUST00000141156.1
Mgarp
mitochondria localized glutamic acid rich protein
chr5_-_139736291 2.486 ENSMUST00000044642.10
Micall2
MICAL-like 2
chr16_-_19883873 2.474 ENSMUST00000100083.3
A930003A15Rik
RIKEN cDNA A930003A15 gene
chr1_-_133690100 2.465 ENSMUST00000169295.1
Lax1
lymphocyte transmembrane adaptor 1
chr11_-_17008647 2.440 ENSMUST00000102881.3
Plek
pleckstrin
chr4_-_63403330 2.417 ENSMUST00000035724.4
Akna
AT-hook transcription factor
chr6_+_29694204 2.404 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr1_+_166130467 2.374 ENSMUST00000166860.1
Gpa33
glycoprotein A33 (transmembrane)
chr8_+_88294204 2.372 ENSMUST00000098521.2
Adcy7
adenylate cyclase 7
chr5_-_34637107 2.360 ENSMUST00000124668.1
ENSMUST00000001109.4
ENSMUST00000155577.1
ENSMUST00000114329.1
Mfsd10



major facilitator superfamily domain containing 10



chr3_-_89418287 2.340 ENSMUST00000029679.3
Cks1b
CDC28 protein kinase 1b
chr13_+_44729535 2.317 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr5_-_34637203 2.294 ENSMUST00000114331.3
Mfsd10
major facilitator superfamily domain containing 10
chr16_+_10170228 2.282 ENSMUST00000044103.5
Rpl39l
ribosomal protein L39-like
chr4_+_127172866 2.270 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr1_+_166130238 2.208 ENSMUST00000060833.7
ENSMUST00000166159.1
Gpa33

glycoprotein A33 (transmembrane)

chr4_-_156255327 2.201 ENSMUST00000179919.1
Samd11
sterile alpha motif domain containing 11
chr8_-_65129317 2.177 ENSMUST00000098713.3
BC030870
cDNA sequence BC030870
chr7_+_30291659 2.175 ENSMUST00000014065.8
ENSMUST00000150892.1
ENSMUST00000126216.1
Clip3


CAP-GLY domain containing linker protein 3


chr15_-_66812593 2.163 ENSMUST00000100572.3
Sla
src-like adaptor
chr16_-_3718105 2.097 ENSMUST00000023180.7
ENSMUST00000100222.2
Mefv

Mediterranean fever

chr19_-_50678642 2.084 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr15_-_97908261 2.083 ENSMUST00000023119.8
Vdr
vitamin D receptor
chr1_+_51987139 2.083 ENSMUST00000168302.1
Stat4
signal transducer and activator of transcription 4
chr14_+_31208309 2.051 ENSMUST00000169169.1
Tnnc1
troponin C, cardiac/slow skeletal
chr4_-_11965699 2.048 ENSMUST00000108301.1
ENSMUST00000095144.3
ENSMUST00000108302.1
Pdp1


pyruvate dehyrogenase phosphatase catalytic subunit 1


chr5_+_110330697 2.011 ENSMUST00000112481.1
Pole
polymerase (DNA directed), epsilon
chr6_-_78378851 1.999 ENSMUST00000089667.1
ENSMUST00000167492.1
Reg3d

regenerating islet-derived 3 delta

chr16_+_19760232 1.994 ENSMUST00000079780.3
ENSMUST00000164397.1
B3gnt5

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5

chr13_+_44729794 1.982 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr11_+_11489266 1.973 ENSMUST00000109678.1
4930415F15Rik
RIKEN cDNA 4930415F15 gene
chr19_+_11404735 1.943 ENSMUST00000153546.1
Ms4a4c
membrane-spanning 4-domains, subfamily A, member 4C
chr7_-_45238794 1.940 ENSMUST00000098461.1
ENSMUST00000107797.1
Cd37

CD37 antigen

chr3_-_52104891 1.928 ENSMUST00000121440.1
Maml3
mastermind like 3 (Drosophila)
chr1_+_40324570 1.926 ENSMUST00000095020.3
Il1rl2
interleukin 1 receptor-like 2
chr11_+_32533290 1.925 ENSMUST00000102821.3
Stk10
serine/threonine kinase 10
chr12_-_8539545 1.916 ENSMUST00000095863.3
ENSMUST00000165657.1
Slc7a15

solute carrier family 7 (cationic amino acid transporter, y+ system), member 15

chr13_+_13437602 1.845 ENSMUST00000005532.7
Nid1
nidogen 1
chr15_+_79516396 1.837 ENSMUST00000010974.7
Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr5_-_131538687 1.802 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr10_+_127323700 1.790 ENSMUST00000069548.5
Arhgap9
Rho GTPase activating protein 9
chr17_+_32403006 1.789 ENSMUST00000065921.5
A530088E08Rik
RIKEN cDNA A530088E08 gene
chr11_-_117779605 1.784 ENSMUST00000143406.1
Tmc6
transmembrane channel-like gene family 6
chr1_-_156474249 1.769 ENSMUST00000051396.6
Soat1
sterol O-acyltransferase 1
chr10_-_117292863 1.739 ENSMUST00000092162.5
Lyz1
lysozyme 1
chr7_-_104950441 1.732 ENSMUST00000179862.1
Gm5900
predicted pseudogene 5900
chr3_-_105932664 1.723 ENSMUST00000098758.2
I830077J02Rik
RIKEN cDNA I830077J02 gene
chr7_+_29983948 1.723 ENSMUST00000148442.1
Zfp568
zinc finger protein 568
chr9_-_120068263 1.719 ENSMUST00000064165.3
ENSMUST00000177637.1
Cx3cr1

chemokine (C-X3-C) receptor 1

chr14_-_20496780 1.676 ENSMUST00000022353.3
Mss51
MSS51 mitochondrial translational activator
chr1_+_75382114 1.672 ENSMUST00000113590.1
ENSMUST00000148515.1
Speg

SPEG complex locus

chr3_+_95160449 1.660 ENSMUST00000090823.1
ENSMUST00000090821.3
Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr10_+_79988584 1.658 ENSMUST00000004784.4
ENSMUST00000105374.1
Cnn2

calponin 2

chrX_+_9350599 1.644 ENSMUST00000073949.2
Gm14501
predicted gene 14501
chr4_-_156228540 1.636 ENSMUST00000105571.2
Plekhn1
pleckstrin homology domain containing, family N member 1
chr17_-_47834682 1.636 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr10_-_23787195 1.601 ENSMUST00000073926.6
Rps12
ribosomal protein S12
chr6_-_16898441 1.598 ENSMUST00000031533.7
Tfec
transcription factor EC
chr1_-_136230289 1.589 ENSMUST00000150163.1
ENSMUST00000144464.1
5730559C18Rik

RIKEN cDNA 5730559C18 gene

chrX_+_164139321 1.559 ENSMUST00000112271.3
Ace2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr7_+_30763750 1.555 ENSMUST00000165887.1
ENSMUST00000085691.4
ENSMUST00000085688.4
ENSMUST00000054427.6
Dmkn



dermokine



chr16_+_19760195 1.548 ENSMUST00000121344.1
B3gnt5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr9_-_119209096 1.545 ENSMUST00000084797.4
Slc22a13
solute carrier family 22 (organic cation transporter), member 13
chr15_-_9529868 1.535 ENSMUST00000003981.4
Il7r
interleukin 7 receptor
chr19_-_50678485 1.532 ENSMUST00000111756.3
Sorcs1
VPS10 domain receptor protein SORCS 1
chrX_+_11302432 1.532 ENSMUST00000179428.1
Gm14474
predicted gene 14474
chr12_-_112860886 1.519 ENSMUST00000021729.7
Gpr132
G protein-coupled receptor 132
chr7_+_130865835 1.485 ENSMUST00000075181.4
ENSMUST00000048180.5
Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

chr3_+_88376023 1.414 ENSMUST00000179946.1
Gm21956
predicted gene, 21956
chr16_+_92485705 1.359 ENSMUST00000162181.1
Clic6
chloride intracellular channel 6
chr6_+_119175247 1.350 ENSMUST00000112777.2
ENSMUST00000073909.5
Dcp1b

DCP1 decapping enzyme homolog B (S. cerevisiae)

chr3_+_129881149 1.342 ENSMUST00000061165.7
Pla2g12a
phospholipase A2, group XIIA
chr6_-_145434925 1.340 ENSMUST00000111708.2
Ifltd1
intermediate filament tail domain containing 1
chr5_-_123879992 1.336 ENSMUST00000164267.1
Gpr81
G protein-coupled receptor 81
chr7_-_125491397 1.330 ENSMUST00000138616.1
Nsmce1
non-SMC element 1 homolog (S. cerevisiae)
chr8_-_119605199 1.326 ENSMUST00000093099.6
Taf1c
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, C
chr16_+_92498122 1.303 ENSMUST00000023670.3
Clic6
chloride intracellular channel 6
chr3_+_87376381 1.277 ENSMUST00000163661.1
ENSMUST00000072480.2
ENSMUST00000167200.1
Fcrl1


Fc receptor-like 1


chr8_+_75214502 1.276 ENSMUST00000132133.1
Rasd2
RASD family, member 2
chrX_+_73123068 1.264 ENSMUST00000179117.1
Gm14685
predicted gene 14685
chr7_+_142434977 1.214 ENSMUST00000118276.1
ENSMUST00000105976.1
ENSMUST00000097939.2
Syt8


synaptotagmin VIII


chr3_+_90603767 1.205 ENSMUST00000001046.5
ENSMUST00000107330.1
S100a4

S100 calcium binding protein A4

chr5_+_33983437 1.197 ENSMUST00000114384.1
ENSMUST00000094869.5
ENSMUST00000114383.1
Gm1673


predicted gene 1673


chr10_-_62231208 1.186 ENSMUST00000047883.9
Tspan15
tetraspanin 15
chr6_-_128300738 1.186 ENSMUST00000143004.1
ENSMUST00000006311.6
ENSMUST00000112157.2
ENSMUST00000133118.1
Tead4



TEA domain family member 4



chr11_-_76571527 1.182 ENSMUST00000072740.6
Abr
active BCR-related gene
chr5_+_33983534 1.182 ENSMUST00000114382.1
Gm1673
predicted gene 1673
chr8_-_82403203 1.182 ENSMUST00000034148.6
Il15
interleukin 15
chrX_+_152781986 1.179 ENSMUST00000026383.3
Gpr143
G protein-coupled receptor 143
chr3_-_103791075 1.172 ENSMUST00000106845.2
ENSMUST00000029438.8
ENSMUST00000121324.1
Hipk1


homeodomain interacting protein kinase 1


chr1_+_170308802 1.129 ENSMUST00000056991.5
1700015E13Rik
RIKEN cDNA 1700015E13 gene
chr1_-_161876656 1.117 ENSMUST00000048377.5
Suco
SUN domain containing ossification factor
chr11_-_103344651 1.099 ENSMUST00000041385.7
Arhgap27
Rho GTPase activating protein 27
chr5_+_108065742 1.083 ENSMUST00000081567.4
ENSMUST00000170319.1
ENSMUST00000112626.1
Mtf2


metal response element binding transcription factor 2


chr7_+_101361250 1.066 ENSMUST00000137384.1
Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr17_-_17883920 1.065 ENSMUST00000061516.7
Fpr1
formyl peptide receptor 1
chr7_-_45759527 1.064 ENSMUST00000075571.7
Sult2b1
sulfotransferase family, cytosolic, 2B, member 1
chr2_+_165055668 1.063 ENSMUST00000081310.4
ENSMUST00000140951.1
Cd40

CD40 antigen

chr7_+_102065713 1.050 ENSMUST00000094129.2
ENSMUST00000094130.2
ENSMUST00000084843.3
Trpc2


transient receptor potential cation channel, subfamily C, member 2


chr4_-_83021102 1.044 ENSMUST00000071708.5
Frem1
Fras1 related extracellular matrix protein 1
chr7_-_125491586 1.036 ENSMUST00000033006.7
Nsmce1
non-SMC element 1 homolog (S. cerevisiae)
chr2_-_119229885 1.033 ENSMUST00000076084.5
Ppp1r14d
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr9_-_43116514 1.032 ENSMUST00000061833.4
Tmem136
transmembrane protein 136
chr14_+_53709902 1.029 ENSMUST00000103638.4
Trav6-7-dv9
T cell receptor alpha variable 6-7-DV9
chr10_+_7667503 1.019 ENSMUST00000040135.8
Nup43
nucleoporin 43
chr17_-_25880236 1.004 ENSMUST00000176696.1
ENSMUST00000095487.5
Wfikkn1

WAP, FS, Ig, KU, and NTR-containing protein 1

chr7_+_127876796 1.002 ENSMUST00000131000.1
Zfp646
zinc finger protein 646
chr11_-_94782500 0.996 ENSMUST00000162809.2
Tmem92
transmembrane protein 92
chr11_-_121118677 0.974 ENSMUST00000039146.3
Tex19.2
testis expressed gene 19.2
chr14_-_70524068 0.974 ENSMUST00000022692.3
Sftpc
surfactant associated protein C
chr9_-_32928928 0.965 ENSMUST00000185169.1
RP24-308I2.1
RP24-308I2.1
chr1_-_75264195 0.938 ENSMUST00000027404.5
Ptprn
protein tyrosine phosphatase, receptor type, N
chr14_-_70175397 0.886 ENSMUST00000143393.1
Pdlim2
PDZ and LIM domain 2
chr7_-_119793958 0.885 ENSMUST00000106523.1
ENSMUST00000063902.7
ENSMUST00000150844.1
Eri2


exoribonuclease 2


chr11_+_77765588 0.881 ENSMUST00000164315.1
Myo18a
myosin XVIIIA
chrX_+_9283764 0.873 ENSMUST00000177926.1
1700012L04Rik
RIKEN cDNA 1700012L04 gene
chr9_-_76567092 0.868 ENSMUST00000183437.1
Fam83b
family with sequence similarity 83, member B
chr16_+_18498768 0.864 ENSMUST00000167778.1
ENSMUST00000139625.1
ENSMUST00000149035.1
ENSMUST00000090086.4
ENSMUST00000115601.1
ENSMUST00000147739.1
ENSMUST00000146673.1
Gnb1l





Gm16314
guanine nucleotide binding protein (G protein), beta polypeptide 1-like





predicted gene 16314
chr17_+_5975740 0.863 ENSMUST00000115790.1
Synj2
synaptojanin 2
chrX_-_163761323 0.853 ENSMUST00000059320.2
Rnf138rt1
ring finger protein 138, retrogene 1
chr11_+_111066154 0.833 ENSMUST00000042970.2
Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
chr8_+_66386292 0.829 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr4_-_136053343 0.824 ENSMUST00000102536.4
Rpl11
ribosomal protein L11
chr5_-_77310049 0.813 ENSMUST00000047860.8
Noa1
nitric oxide associated 1
chr7_+_119794102 0.812 ENSMUST00000084644.2
2610020H08Rik
RIKEN cDNA 2610020H08 gene
chr15_-_36608959 0.800 ENSMUST00000001809.8
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr17_-_13052280 0.776 ENSMUST00000091648.2
Gpr31b
G protein-coupled receptor 31, D17Leh66b region
chr4_+_86930691 0.768 ENSMUST00000164590.1
Acer2
alkaline ceramidase 2
chr6_+_115134899 0.754 ENSMUST00000009538.5
ENSMUST00000169345.1
Syn2

synapsin II

chr7_+_119793987 0.748 ENSMUST00000033218.8
ENSMUST00000106520.1
2610020H08Rik

RIKEN cDNA 2610020H08 gene

chr1_+_170232749 0.713 ENSMUST00000162752.1
Sh2d1b2
SH2 domain protein 1B2
chr18_-_37638719 0.710 ENSMUST00000058635.2
Slc25a2
solute carrier family 25 (mitochondrial carrier, ornithine transporter) member 2
chr19_-_5912771 0.704 ENSMUST00000118623.1
Dpf2
D4, zinc and double PHD fingers family 2
chr7_-_127208423 0.699 ENSMUST00000120705.1
Tbc1d10b
TBC1 domain family, member 10b
chr13_+_111867931 0.697 ENSMUST00000128198.1
Gm15326
predicted gene 15326
chr2_+_165055625 0.692 ENSMUST00000017799.5
ENSMUST00000073707.2
Cd40

CD40 antigen

chr8_+_104340594 0.691 ENSMUST00000034343.4
Cmtm3
CKLF-like MARVEL transmembrane domain containing 3
chr7_+_102065485 0.689 ENSMUST00000106950.1
ENSMUST00000146450.1
Trpc2

transient receptor potential cation channel, subfamily C, member 2

chr7_+_101896817 0.681 ENSMUST00000143835.1
Anapc15
anaphase prompoting complex C subunit 15
chr5_+_77310147 0.673 ENSMUST00000031167.5
Polr2b
polymerase (RNA) II (DNA directed) polypeptide B
chr5_+_17574268 0.664 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr10_-_117238665 0.659 ENSMUST00000020392.4
9530003J23Rik
RIKEN cDNA 9530003J23 gene
chr12_-_80260356 0.643 ENSMUST00000021554.8
Actn1
actinin, alpha 1
chr3_+_98222148 0.641 ENSMUST00000029469.4
Reg4
regenerating islet-derived family, member 4
chr12_+_83950608 0.637 ENSMUST00000053744.7
2410016O06Rik
RIKEN cDNA 2410016O06 gene
chr11_+_98383811 0.632 ENSMUST00000008021.2
Tcap
titin-cap
chr12_+_65075582 0.629 ENSMUST00000058889.4
Fancm
Fanconi anemia, complementation group M

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 15.0 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
3.7 14.6 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
1.9 15.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.3 5.4 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
1.2 3.5 GO:0033624 negative regulation of integrin activation(GO:0033624)
1.1 3.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
1.0 4.0 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
1.0 15.6 GO:0070493 thrombin-activated receptor signaling pathway(GO:0070493)
0.9 4.7 GO:0042891 antibiotic transport(GO:0042891)
0.9 8.0 GO:0097211 axonal transport of mitochondrion(GO:0019896) response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.9 2.6 GO:0002358 B cell homeostatic proliferation(GO:0002358)
0.9 6.9 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.9 6.0 GO:0046208 spermine catabolic process(GO:0046208)
0.8 3.1 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.7 3.6 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.7 2.1 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.7 2.0 GO:0045004 DNA replication proofreading(GO:0045004)
0.6 1.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.5 3.3 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.5 4.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.5 2.1 GO:0071608 macrophage inflammatory protein-1 alpha production(GO:0071608)
0.5 2.1 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.5 5.8 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.4 5.7 GO:0060352 cell adhesion molecule production(GO:0060352)
0.4 1.2 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) extrathymic T cell selection(GO:0045062) cellular response to interleukin-15(GO:0071350) regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.4 1.6 GO:1903598 tryptophan transport(GO:0015827) positive regulation of gap junction assembly(GO:1903598)
0.4 3.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.4 1.9 GO:0071593 lymphocyte aggregation(GO:0071593)
0.3 1.7 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.3 1.7 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.3 0.9 GO:0061792 secretory granule maturation(GO:0061792)
0.3 4.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 5.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.3 0.8 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.3 0.8 GO:0060796 endodermal cell fate determination(GO:0007493) regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796) regulation of cardiac cell fate specification(GO:2000043)
0.3 1.8 GO:0006621 protein retention in ER lumen(GO:0006621)
0.3 3.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.3 0.8 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.2 1.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.2 0.7 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.2 1.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.2 7.0 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 0.9 GO:1903028 asymmetric Golgi ribbon formation(GO:0090164) regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.2 5.0 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.2 1.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.2 1.1 GO:0000103 sulfate assimilation(GO:0000103)
0.2 3.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 4.6 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.2 1.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.2 2.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 3.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 1.9 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.2 3.1 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.2 1.5 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.2 1.8 GO:0042984 very-low-density lipoprotein particle assembly(GO:0034379) amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.2 1.9 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 1.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 1.2 GO:1903056 regulation of melanosome organization(GO:1903056)
0.2 2.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.2 3.3 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.2 0.8 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.2 0.8 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.2 0.8 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 1.8 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 2.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 2.0 GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872)
0.1 8.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 2.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.5 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.1 0.6 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 0.4 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.6 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 2.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.3 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.1 1.5 GO:0015747 urate transport(GO:0015747)
0.1 0.6 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.1 0.6 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.8 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 0.3 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.7 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 1.2 GO:0061072 iris morphogenesis(GO:0061072)
0.1 0.7 GO:0060666 pulmonary myocardium development(GO:0003350) dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 2.4 GO:0006301 postreplication repair(GO:0006301)
0.1 0.3 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.4 GO:0008380 RNA splicing(GO:0008380)
0.1 0.3 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) snoRNA polyadenylation(GO:0071050) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 1.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.5 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 1.7 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.1 7.5 GO:0042100 B cell proliferation(GO:0042100)
0.1 0.2 GO:0040010 positive regulation of growth rate(GO:0040010)
0.1 1.9 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.1 1.6 GO:0009950 dorsal/ventral axis specification(GO:0009950) trophoblast giant cell differentiation(GO:0060707)
0.1 0.5 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.1 0.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.4 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.9 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.5 GO:0008209 androgen metabolic process(GO:0008209)
0.1 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.2 GO:0046370 fructose biosynthetic process(GO:0046370)
0.1 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.6 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 4.4 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 2.5 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:1905595 negative regulation of low-density lipoprotein particle clearance(GO:0010989) regulation of low-density lipoprotein particle receptor binding(GO:1905595)
0.0 2.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.3 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.1 GO:0015828 tyrosine transport(GO:0015828)
0.0 1.1 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 2.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.8 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 1.5 GO:0007340 membrane fusion involved in acrosome reaction(GO:0002078) acrosome reaction(GO:0007340) acrosomal vesicle exocytosis(GO:0060478)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 3.5 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.8 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 1.0 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 1.5 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.2 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.0 0.4 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 1.1 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.4 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.9 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 1.9 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 1.7 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 1.0 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.4 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.0 1.2 GO:0035304 regulation of protein dephosphorylation(GO:0035304)
0.0 0.5 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0 1.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0001771 immunological synapse formation(GO:0001771)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 14.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
1.0 9.5 GO:0042581 specific granule(GO:0042581)
0.9 15.0 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.4 2.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.4 2.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.3 2.1 GO:0001651 dense fibrillar component(GO:0001651)
0.3 2.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.3 2.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.3 3.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.3 1.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.3 4.0 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.3 1.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.3 8.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.3 3.1 GO:0005861 troponin complex(GO:0005861)
0.2 0.6 GO:0032127 dense core granule membrane(GO:0032127)
0.2 3.1 GO:0051286 cell tip(GO:0051286)
0.2 5.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 1.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009) pigment granule membrane(GO:0090741)
0.2 5.2 GO:0097228 sperm principal piece(GO:0097228)
0.1 4.0 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.8 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 2.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 8.3 GO:0031985 Golgi cisterna(GO:0031985)
0.1 7.0 GO:0034707 chloride channel complex(GO:0034707)
0.1 3.5 GO:0051233 spindle midzone(GO:0051233)
0.1 5.6 GO:0031901 early endosome membrane(GO:0031901)
0.1 2.7 GO:0005859 muscle myosin complex(GO:0005859) myosin filament(GO:0032982)
0.1 1.0 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 2.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.0 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 1.8 GO:0005605 basal lamina(GO:0005605)
0.1 1.8 GO:0043196 varicosity(GO:0043196)
0.1 0.9 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 5.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.3 GO:0031523 Myb complex(GO:0031523)
0.1 1.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 1.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.7 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.4 GO:0016460 myosin II complex(GO:0016460)
0.0 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 8.1 GO:0005903 brush border(GO:0005903)
0.0 2.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 6.5 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 5.7 GO:0005769 early endosome(GO:0005769)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.6 GO:0001741 XY body(GO:0001741)
0.0 2.1 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 5.9 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.8 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 1.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.4 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 2.1 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.5 GO:0000932 P-body(GO:0000932)
0.0 2.6 GO:0012506 vesicle membrane(GO:0012506)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.6 GO:0005844 polysome(GO:0005844)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 13.2 GO:0015057 thrombin-activated receptor activity(GO:0015057)
2.0 6.0 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
1.9 5.7 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
1.6 14.6 GO:0033691 sialic acid binding(GO:0033691)
1.2 3.5 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
1.0 15.3 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.9 4.7 GO:0042895 antibiotic transporter activity(GO:0042895)
0.9 2.7 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.8 5.4 GO:0032027 myosin light chain binding(GO:0032027)
0.7 2.1 GO:1902121 calcitriol receptor activity(GO:0008434) calcitriol binding(GO:1902098) lithocholic acid binding(GO:1902121)
0.6 1.9 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.6 2.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.5 2.2 GO:0035594 ganglioside binding(GO:0035594)
0.5 2.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.5 1.8 GO:0046923 ER retention sequence binding(GO:0046923)
0.4 3.1 GO:0030911 TPR domain binding(GO:0030911)
0.4 2.2 GO:0042731 PH domain binding(GO:0042731)
0.3 1.7 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.3 10.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.3 2.1 GO:0031013 troponin I binding(GO:0031013)
0.3 2.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.3 4.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3 0.8 GO:0071633 dihydroceramidase activity(GO:0071633)
0.3 2.0 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.2 15.0 GO:0004601 peroxidase activity(GO:0004601)
0.2 1.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 6.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 10.0 GO:0050699 WW domain binding(GO:0050699)
0.2 0.4 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.2 1.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 1.1 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.1 2.1 GO:0003796 lysozyme activity(GO:0003796)
0.1 3.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.7 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 2.7 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 1.2 GO:0035240 dopamine binding(GO:0035240)
0.1 2.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.6 GO:0051373 FATZ binding(GO:0051373)
0.1 5.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.4 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 2.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 3.3 GO:0043274 phospholipase binding(GO:0043274)
0.1 3.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.6 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.8 GO:1990948 ubiquitin ligase inhibitor activity(GO:1990948)
0.1 4.3 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.8 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.8 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 6.9 GO:0097110 scaffold protein binding(GO:0097110)
0.1 0.2 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.1 3.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.9 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 3.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.7 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 2.5 GO:0042805 actinin binding(GO:0042805)
0.1 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004) neurotrophin receptor activity(GO:0005030)
0.1 0.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 1.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 2.5 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.2 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.1 0.1 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.1 2.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.6 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.6 GO:0030247 polysaccharide binding(GO:0030247)
0.1 0.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 3.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 1.5 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 1.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.0 1.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 1.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0034190 very-low-density lipoprotein particle binding(GO:0034189) apolipoprotein receptor binding(GO:0034190)
0.0 1.9 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 10.4 GO:0045296 cadherin binding(GO:0045296)
0.0 1.2 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.8 GO:0042287 MHC protein binding(GO:0042287)
0.0 9.5 GO:0005525 GTP binding(GO:0005525)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.9 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 1.1 GO:0140034 methylated histone binding(GO:0035064) methylation-dependent protein binding(GO:0140034)
0.0 1.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 2.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.4 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.3 17.1 PID_IL23_PATHWAY IL23-mediated signaling events
0.2 9.2 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.2 15.3 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.5 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.1 4.7 PID_ARF6_PATHWAY Arf6 signaling events
0.1 1.8 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.1 2.4 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 1.1 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 4.4 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 2.3 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 1.6 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.8 PID_ARF_3PATHWAY Arf1 pathway
0.0 1.8 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 3.2 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.1 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 3.0 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.2 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 6.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.4 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 2.3 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.5 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 1.3 PID_P73PATHWAY p73 transcription factor network
0.0 0.4 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.2 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.4 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.4 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.7 15.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4 6.0 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.2 11.2 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.2 2.1 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 2.4 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 2.0 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 8.7 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 2.1 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 3.2 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.9 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 5.8 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.1 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.3 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 4.0 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.1 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.0 2.3 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 3.3 REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 1.0 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.7 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 2.3 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 4.1 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.2 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.0 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.9 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 1.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 3.3 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.5 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.9 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.7 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.8 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 0.3 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.1 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse