Motif ID: Ets2

Z-value: 1.523


Transcription factors associated with Ets2:

Gene SymbolEntrez IDGene Name
Ets2 ENSMUSG00000022895.8 Ets2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ets2mm10_v2_chr16_+_95702044_95702094-0.325.4e-02Click!


Activity profile for motif Ets2.

activity profile for motif Ets2


Sorted Z-values histogram for motif Ets2

Sorted Z-values for motif Ets2



Network of associatons between targets according to the STRING database.



First level regulatory network of Ets2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_32917320 13.188 ENSMUST00000179434.1
Cyp4f14
cytochrome P450, family 4, subfamily f, polypeptide 14
chr17_-_32917048 13.177 ENSMUST00000054174.7
Cyp4f14
cytochrome P450, family 4, subfamily f, polypeptide 14
chr8_+_105269837 10.504 ENSMUST00000172525.1
ENSMUST00000174837.1
ENSMUST00000173859.1
Hsf4


heat shock transcription factor 4


chr8_+_105269788 10.399 ENSMUST00000036127.2
ENSMUST00000163734.2
Hsf4

heat shock transcription factor 4

chr10_+_87861309 8.852 ENSMUST00000122100.1
Igf1
insulin-like growth factor 1
chr8_+_105131800 7.961 ENSMUST00000161289.1
Ces4a
carboxylesterase 4A
chr18_-_38929148 6.957 ENSMUST00000134864.1
Fgf1
fibroblast growth factor 1
chr1_-_121327672 6.746 ENSMUST00000159085.1
ENSMUST00000159125.1
ENSMUST00000161818.1
Insig2


insulin induced gene 2


chr16_-_18089022 6.695 ENSMUST00000132241.1
ENSMUST00000139861.1
ENSMUST00000003620.5
Prodh


proline dehydrogenase


chr15_+_10177623 6.395 ENSMUST00000124470.1
Prlr
prolactin receptor
chr1_-_121327734 6.344 ENSMUST00000160968.1
ENSMUST00000162582.1
Insig2

insulin induced gene 2

chr10_-_95324072 6.139 ENSMUST00000053594.5
Cradd
CASP2 and RIPK1 domain containing adaptor with death domain
chr1_-_121327776 6.051 ENSMUST00000160688.1
Insig2
insulin induced gene 2
chr14_+_65969714 5.896 ENSMUST00000153460.1
Clu
clusterin
chr19_+_41029275 5.822 ENSMUST00000051806.4
ENSMUST00000112200.1
Dntt

deoxynucleotidyltransferase, terminal

chr10_-_40025253 5.641 ENSMUST00000163705.2
AI317395
expressed sequence AI317395
chr5_-_139814025 5.601 ENSMUST00000146780.1
Tmem184a
transmembrane protein 184a
chr11_+_70092634 5.382 ENSMUST00000102572.1
Asgr2
asialoglycoprotein receptor 2
chr11_+_70092705 5.182 ENSMUST00000124721.1
Asgr2
asialoglycoprotein receptor 2
chr19_+_3986564 5.133 ENSMUST00000054030.7
Acy3
aspartoacylase (aminoacylase) 3
chr11_+_70092653 5.079 ENSMUST00000143772.1
Asgr2
asialoglycoprotein receptor 2
chr9_+_7445822 5.034 ENSMUST00000034497.6
Mmp3
matrix metallopeptidase 3
chr1_-_121328024 4.604 ENSMUST00000003818.7
Insig2
insulin induced gene 2
chr7_+_143473736 4.511 ENSMUST00000052348.5
Slc22a18
solute carrier family 22 (organic cation transporter), member 18
chr9_-_106476590 4.489 ENSMUST00000112479.2
Parp3
poly (ADP-ribose) polymerase family, member 3
chr7_+_87246649 4.225 ENSMUST00000068829.5
ENSMUST00000032781.7
Nox4

NADPH oxidase 4

chr17_-_56121946 4.193 ENSMUST00000041357.7
Lrg1
leucine-rich alpha-2-glycoprotein 1
chr5_-_25100624 4.158 ENSMUST00000030784.7
Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr6_-_146502099 4.117 ENSMUST00000053273.8
Itpr2
inositol 1,4,5-triphosphate receptor 2
chr4_-_149485157 4.103 ENSMUST00000126896.1
ENSMUST00000105693.1
ENSMUST00000030845.6
Nmnat1


nicotinamide nucleotide adenylyltransferase 1


chr11_-_20112876 4.087 ENSMUST00000000137.7
Actr2
ARP2 actin-related protein 2
chr5_-_139814231 4.031 ENSMUST00000044002.4
Tmem184a
transmembrane protein 184a
chr7_-_30592941 3.991 ENSMUST00000108151.2
Zbtb32
zinc finger and BTB domain containing 32
chr18_+_56432116 3.899 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr3_+_94693556 3.806 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
Selenbp2



selenium binding protein 2



chr11_-_48816936 3.730 ENSMUST00000140800.1
Trim41
tripartite motif-containing 41
chr2_-_5714490 3.727 ENSMUST00000044009.7
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr5_-_38480131 3.671 ENSMUST00000143758.1
ENSMUST00000067886.5
Slc2a9

solute carrier family 2 (facilitated glucose transporter), member 9

chr4_-_140617062 3.661 ENSMUST00000154979.1
Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chr11_+_87592145 3.531 ENSMUST00000103179.3
ENSMUST00000092802.5
ENSMUST00000146871.1
Mtmr4


myotubularin related protein 4


chr11_-_105944412 3.520 ENSMUST00000019734.4
ENSMUST00000184269.1
ENSMUST00000150563.1
Cyb561


cytochrome b-561


chr4_+_41760454 3.414 ENSMUST00000108040.1
Il11ra1
interleukin 11 receptor, alpha chain 1
chr1_+_16688405 3.372 ENSMUST00000026881.4
Ly96
lymphocyte antigen 96
chr12_-_28623282 3.358 ENSMUST00000036136.7
Colec11
collectin sub-family member 11
chr6_+_54039558 3.326 ENSMUST00000046856.7
Chn2
chimerin (chimaerin) 2
chr2_-_120314141 3.311 ENSMUST00000054651.7
Pla2g4f
phospholipase A2, group IVF
chr9_+_110476985 3.289 ENSMUST00000084948.4
ENSMUST00000061155.6
ENSMUST00000140686.1
ENSMUST00000084952.5
Kif9



kinesin family member 9



chr12_-_103830373 3.274 ENSMUST00000164454.2
Serpina1b
serine (or cysteine) preptidase inhibitor, clade A, member 1B
chr14_-_18239053 3.268 ENSMUST00000090543.5
Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr11_-_82764303 3.266 ENSMUST00000021040.3
ENSMUST00000100722.4
Cct6b

chaperonin containing Tcp1, subunit 6b (zeta)

chr11_-_70646972 3.241 ENSMUST00000014750.8
Slc25a11
solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11
chr17_+_32685610 3.224 ENSMUST00000168171.1
Cyp4f15
cytochrome P450, family 4, subfamily f, polypeptide 15
chr19_+_18631927 3.224 ENSMUST00000159572.1
ENSMUST00000042392.7
Nmrk1

nicotinamide riboside kinase 1

chr11_-_4160286 3.211 ENSMUST00000093381.4
ENSMUST00000101626.2
Ccdc157

coiled-coil domain containing 157

chr4_+_43562672 3.207 ENSMUST00000167751.1
ENSMUST00000132631.1
Creb3

cAMP responsive element binding protein 3

chr6_+_54039935 3.174 ENSMUST00000114403.1
Chn2
chimerin (chimaerin) 2
chr15_-_89170688 3.155 ENSMUST00000060808.9
Plxnb2
plexin B2
chr8_-_25785154 3.145 ENSMUST00000038498.8
Bag4
BCL2-associated athanogene 4
chr17_+_32685655 3.142 ENSMUST00000008801.6
Cyp4f15
cytochrome P450, family 4, subfamily f, polypeptide 15
chr4_-_140581774 3.100 ENSMUST00000147426.1
ENSMUST00000105797.2
Arhgef10l

Rho guanine nucleotide exchange factor (GEF) 10-like

chr8_-_22476809 3.066 ENSMUST00000163774.1
ENSMUST00000033935.8
Smim19

small integral membrane protein 19

chr9_-_29411736 3.058 ENSMUST00000115236.1
Ntm
neurotrimin
chr14_+_53649387 3.033 ENSMUST00000103660.2
Trav15-2-dv6-2
T cell receptor alpha variable 15-2-DV6-2
chr3_-_87768966 2.949 ENSMUST00000174776.1
Pear1
platelet endothelial aggregation receptor 1
chr16_+_3872368 2.857 ENSMUST00000151988.1
Naa60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr2_+_32646586 2.793 ENSMUST00000009705.7
ENSMUST00000167841.1
Eng

endoglin

chr2_-_25500613 2.776 ENSMUST00000040042.4
C8g
complement component 8, gamma polypeptide
chr4_-_107923519 2.775 ENSMUST00000106719.1
ENSMUST00000106720.2
ENSMUST00000131644.1
ENSMUST00000030345.8
Cpt2



carnitine palmitoyltransferase 2



chr10_+_21377290 2.773 ENSMUST00000042699.7
ENSMUST00000159163.1
Aldh8a1

aldehyde dehydrogenase 8 family, member A1

chr15_+_10714836 2.730 ENSMUST00000180604.1
4930556M19Rik
RIKEN cDNA 4930556M19 gene
chr6_+_54040078 2.727 ENSMUST00000127323.2
Chn2
chimerin (chimaerin) 2
chr9_+_70207342 2.723 ENSMUST00000034745.7
Myo1e
myosin IE
chr17_+_88626569 2.647 ENSMUST00000150023.1
Ston1
stonin 1
chr16_-_38522662 2.611 ENSMUST00000002925.5
Timmdc1
translocase of inner mitochondrial membrane domain containing 1
chr4_-_124850670 2.609 ENSMUST00000163946.1
ENSMUST00000106190.3
1110065P20Rik

RIKEN cDNA 1110065P20 gene

chr6_+_21986887 2.608 ENSMUST00000151315.1
Cped1
cadherin-like and PC-esterase domain containing 1
chr13_-_59823072 2.588 ENSMUST00000071703.4
Zcchc6
zinc finger, CCHC domain containing 6
chr6_-_114969986 2.582 ENSMUST00000139640.1
Vgll4
vestigial like 4 (Drosophila)
chr16_-_44016387 2.561 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chr4_+_133518963 2.536 ENSMUST00000149807.1
ENSMUST00000042919.9
ENSMUST00000153811.1
ENSMUST00000105901.1
ENSMUST00000121797.1
1810019J16Rik




RIKEN cDNA 1810019J16 gene




chr4_-_149485202 2.521 ENSMUST00000119921.1
Nmnat1
nicotinamide nucleotide adenylyltransferase 1
chr19_-_29047847 2.514 ENSMUST00000025696.4
Ak3
adenylate kinase 3
chr7_+_65693447 2.510 ENSMUST00000143508.1
Tm2d3
TM2 domain containing 3
chr1_-_91413163 2.468 ENSMUST00000086851.1
Hes6
hairy and enhancer of split 6
chr9_+_32224457 2.420 ENSMUST00000183121.1
Arhgap32
Rho GTPase activating protein 32
chr17_+_3397189 2.417 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr15_-_10714612 2.403 ENSMUST00000169385.1
Rai14
retinoic acid induced 14
chr6_+_21986438 2.387 ENSMUST00000115382.1
Cped1
cadherin-like and PC-esterase domain containing 1
chr15_+_94543605 2.377 ENSMUST00000074936.3
Irak4
interleukin-1 receptor-associated kinase 4
chr15_-_37458523 2.342 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr1_+_74601548 2.324 ENSMUST00000087186.4
Stk36
serine/threonine kinase 36
chr11_-_48817332 2.303 ENSMUST00000047145.7
Trim41
tripartite motif-containing 41
chr9_-_103219823 2.301 ENSMUST00000168142.1
Trf
transferrin
chr6_-_72362382 2.271 ENSMUST00000114095.1
ENSMUST00000069595.6
ENSMUST00000069580.5
Rnf181


ring finger protein 181


chr1_+_74284930 2.252 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
Pnkd


paroxysmal nonkinesiogenic dyskinesia


chr9_-_79793378 2.229 ENSMUST00000034878.5
Tmem30a
transmembrane protein 30A
chr11_+_70647258 2.223 ENSMUST00000037534.7
Rnf167
ring finger protein 167
chr14_+_78849171 2.216 ENSMUST00000040990.5
Vwa8
von Willebrand factor A domain containing 8
chr19_+_6363719 2.216 ENSMUST00000113489.1
ENSMUST00000113488.1
Sf1

splicing factor 1

chr10_-_83648713 2.184 ENSMUST00000020500.7
Appl2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr5_+_105732063 2.182 ENSMUST00000154807.1
Lrrc8d
leucine rich repeat containing 8D
chr6_-_122282810 2.170 ENSMUST00000032207.8
Klrg1
killer cell lectin-like receptor subfamily G, member 1
chr5_-_116422858 2.160 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr9_-_79793507 2.154 ENSMUST00000120690.1
Tmem30a
transmembrane protein 30A
chr11_-_50325599 2.129 ENSMUST00000179865.1
ENSMUST00000020637.8
Canx

calnexin

chr4_-_124850473 2.106 ENSMUST00000137769.2
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chr1_-_131276914 2.103 ENSMUST00000161764.1
Ikbke
inhibitor of kappaB kinase epsilon
chr4_+_138304723 2.089 ENSMUST00000030538.4
Ddost
dolichyl-di-phosphooligosaccharide-protein glycotransferase
chr2_-_73386396 2.088 ENSMUST00000112044.1
ENSMUST00000112043.1
ENSMUST00000076463.5
Gpr155


G protein-coupled receptor 155


chr13_-_103920508 2.085 ENSMUST00000053927.5
ENSMUST00000091269.4
ENSMUST00000022222.5
Erbb2ip


Erbb2 interacting protein


chr8_+_22476700 2.075 ENSMUST00000067786.7
Slc20a2
solute carrier family 20, member 2
chr5_-_36830647 2.056 ENSMUST00000031002.3
Man2b2
mannosidase 2, alpha B2
chr13_-_103920295 2.015 ENSMUST00000169083.1
Erbb2ip
Erbb2 interacting protein
chr7_-_126585775 2.014 ENSMUST00000084589.4
Cln3
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr11_-_109722214 2.011 ENSMUST00000020938.7
Fam20a
family with sequence similarity 20, member A
chr19_+_6363671 2.006 ENSMUST00000131252.1
Sf1
splicing factor 1
chr13_-_29984219 2.006 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr10_-_83648631 2.001 ENSMUST00000146876.2
ENSMUST00000176294.1
Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chr5_+_34543365 1.993 ENSMUST00000101316.3
Sh3bp2
SH3-domain binding protein 2
chr2_+_91202885 1.988 ENSMUST00000150403.1
ENSMUST00000002172.7
ENSMUST00000155418.1
Acp2


acid phosphatase 2, lysosomal


chr1_-_155527083 1.978 ENSMUST00000097531.2
Gm5532
predicted gene 5532
chr1_+_74601441 1.957 ENSMUST00000087183.4
ENSMUST00000148456.1
ENSMUST00000113694.1
Stk36


serine/threonine kinase 36


chr6_-_119388671 1.956 ENSMUST00000169744.1
Adipor2
adiponectin receptor 2
chr9_+_45055211 1.948 ENSMUST00000114663.2
Mpzl3
myelin protein zero-like 3
chr4_-_124850652 1.947 ENSMUST00000125776.1
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chr8_+_119437118 1.947 ENSMUST00000152420.1
ENSMUST00000098365.3
Osgin1

oxidative stress induced growth inhibitor 1

chr3_+_90080442 1.944 ENSMUST00000127955.1
Tpm3
tropomyosin 3, gamma
chr9_-_63602417 1.941 ENSMUST00000171243.1
ENSMUST00000163982.1
ENSMUST00000163624.1
Iqch


IQ motif containing H


chr16_-_38713235 1.936 ENSMUST00000023487.4
Arhgap31
Rho GTPase activating protein 31
chr7_+_65693417 1.917 ENSMUST00000032726.7
ENSMUST00000107495.3
Tm2d3

TM2 domain containing 3

chr17_-_6948283 1.915 ENSMUST00000024572.9
Rsph3b
radial spoke 3B homolog (Chlamydomonas)
chr15_+_9140527 1.906 ENSMUST00000090380.4
Lmbrd2
LMBR1 domain containing 2
chr7_-_105399991 1.896 ENSMUST00000118726.1
ENSMUST00000074686.7
ENSMUST00000122327.1
ENSMUST00000179474.1
ENSMUST00000048079.6
Fam160a2




family with sequence similarity 160, member A2




chr7_-_68353182 1.895 ENSMUST00000123509.1
ENSMUST00000129965.1
Gm16158

predicted gene 16158

chrX_-_134276888 1.894 ENSMUST00000113252.1
Trmt2b
TRM2 tRNA methyltransferase 2B
chr15_-_54278420 1.879 ENSMUST00000079772.3
Tnfrsf11b
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
chr3_+_89418443 1.867 ENSMUST00000039110.5
ENSMUST00000125036.1
ENSMUST00000154791.1
ENSMUST00000128238.1
ENSMUST00000107417.2
Shc1




src homology 2 domain-containing transforming protein C1




chr9_+_32224246 1.853 ENSMUST00000168954.2
Arhgap32
Rho GTPase activating protein 32
chr7_-_126584578 1.839 ENSMUST00000150311.1
Cln3
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr9_-_110476637 1.834 ENSMUST00000111934.1
ENSMUST00000068025.6
Klhl18

kelch-like 18

chr14_+_20348159 1.812 ENSMUST00000090503.4
ENSMUST00000090499.5
ENSMUST00000037698.5
ENSMUST00000051915.6
Fam149b



family with sequence similarity 149, member B



chr6_-_122340200 1.809 ENSMUST00000159384.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr2_-_163419508 1.791 ENSMUST00000046908.3
Oser1
oxidative stress responsive serine rich 1
chr8_-_36952414 1.769 ENSMUST00000163663.2
Dlc1
deleted in liver cancer 1
chr14_+_41131777 1.757 ENSMUST00000022314.3
ENSMUST00000170719.1
Sftpa1

surfactant associated protein A1

chr11_-_5542177 1.756 ENSMUST00000020776.4
Ccdc117
coiled-coil domain containing 117
chr9_-_63602464 1.755 ENSMUST00000080527.5
ENSMUST00000042322.4
Iqch

IQ motif containing H

chr3_+_82358056 1.755 ENSMUST00000091014.4
Map9
microtubule-associated protein 9
chr10_+_4611971 1.753 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1

estrogen receptor 1 (alpha)

chr11_+_94565039 1.753 ENSMUST00000040418.8
Chad
chondroadherin
chr15_-_94589870 1.736 ENSMUST00000023087.6
ENSMUST00000152590.1
Twf1

twinfilin, actin-binding protein, homolog 1 (Drosophila)

chr6_+_29348069 1.729 ENSMUST00000173216.1
ENSMUST00000031779.10
ENSMUST00000090481.7
Calu


calumenin


chr4_+_103313806 1.719 ENSMUST00000035780.3
Oma1
OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
chr5_+_105731755 1.717 ENSMUST00000127686.1
Lrrc8d
leucine rich repeat containing 8D
chr18_-_7004717 1.708 ENSMUST00000079788.4
Mkx
mohawk homeobox
chr2_-_167060417 1.707 ENSMUST00000155281.1
Znfx1
zinc finger, NFX1-type containing 1
chr4_+_136469755 1.702 ENSMUST00000170102.1
ENSMUST00000105849.2
ENSMUST00000129230.2
Luzp1


leucine zipper protein 1


chr2_-_168734236 1.696 ENSMUST00000109175.2
Atp9a
ATPase, class II, type 9A
chr17_+_28272191 1.689 ENSMUST00000169040.1
Ppard
peroxisome proliferator activator receptor delta
chr2_-_103303158 1.683 ENSMUST00000111176.2
Ehf
ets homologous factor
chr5_+_143181010 1.679 ENSMUST00000031574.3
4933411G11Rik
RIKEN cDNA 4933411G11Rik gene
chr7_-_80232479 1.671 ENSMUST00000123279.1
Cib1
calcium and integrin binding 1 (calmyrin)
chr7_+_12834743 1.670 ENSMUST00000004614.8
Zfp110
zinc finger protein 110
chr11_-_23497867 1.670 ENSMUST00000128559.1
ENSMUST00000147157.1
ENSMUST00000109539.1
Ahsa2


AHA1, activator of heat shock protein ATPase 2


chr1_-_183297008 1.665 ENSMUST00000057062.5
Brox
BRO1 domain and CAAX motif containing
chr8_+_85060055 1.664 ENSMUST00000095220.3
Fbxw9
F-box and WD-40 domain protein 9
chr11_-_116307168 1.663 ENSMUST00000124281.1
Exoc7
exocyst complex component 7
chr16_-_64771146 1.662 ENSMUST00000076991.6
4930453N24Rik
RIKEN cDNA 4930453N24 gene
chr11_-_113565740 1.646 ENSMUST00000071539.3
ENSMUST00000106633.3
ENSMUST00000042657.9
ENSMUST00000149034.1
Slc39a11



solute carrier family 39 (metal ion transporter), member 11



chr12_+_76533540 1.642 ENSMUST00000075249.4
Plekhg3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr8_+_105326354 1.637 ENSMUST00000015000.5
ENSMUST00000098453.2
Tmem208

transmembrane protein 208

chr11_-_23498025 1.624 ENSMUST00000020529.6
Ahsa2
AHA1, activator of heat shock protein ATPase 2
chr8_-_85840877 1.613 ENSMUST00000034140.7
Itfg1
integrin alpha FG-GAP repeat containing 1
chr10_+_59221945 1.611 ENSMUST00000182161.1
Sowahc
sosondowah ankyrin repeat domain family member C
chr7_-_67645195 1.610 ENSMUST00000032775.5
ENSMUST00000053950.2
Lrrc28

leucine rich repeat containing 28

chr19_+_47854970 1.603 ENSMUST00000026050.7
Gsto1
glutathione S-transferase omega 1
chr9_-_44965519 1.587 ENSMUST00000125642.1
ENSMUST00000117506.1
ENSMUST00000117549.1
Ube4a


ubiquitination factor E4A, UFD2 homolog (S. cerevisiae)


chr3_+_108571699 1.582 ENSMUST00000143054.1
Taf13
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr9_+_35211155 1.581 ENSMUST00000034541.5
Srpr
signal recognition particle receptor ('docking protein')
chr17_+_88626549 1.574 ENSMUST00000163588.1
ENSMUST00000064035.6
Ston1

stonin 1

chrX_-_108664891 1.561 ENSMUST00000178160.1
Gm379
predicted gene 379
chr11_+_29692937 1.556 ENSMUST00000102843.3
ENSMUST00000102842.3
ENSMUST00000078830.4
ENSMUST00000170731.1
Rtn4



reticulon 4



chr7_+_44850393 1.552 ENSMUST00000136232.1
Akt1s1
AKT1 substrate 1 (proline-rich)
chr8_+_110847015 1.549 ENSMUST00000172668.1
ENSMUST00000034203.10
ENSMUST00000174398.1
Cog4


component of oligomeric golgi complex 4


chr7_+_44896125 1.548 ENSMUST00000166552.1
ENSMUST00000168207.1
Fuz

fuzzy homolog (Drosophila)

chrX_-_12762069 1.543 ENSMUST00000096495.4
ENSMUST00000076016.5
Med14

mediator complex subunit 14

chr18_+_36783222 1.538 ENSMUST00000019287.8
Hars2
histidyl-tRNA synthetase 2, mitochondrial (putative)
chrX_-_103981242 1.536 ENSMUST00000121153.1
ENSMUST00000070705.4
Rlim

ring finger protein, LIM domain interacting

chr10_+_61297809 1.531 ENSMUST00000035419.5
Prf1
perforin 1 (pore forming protein)
chr2_-_103303179 1.526 ENSMUST00000090475.3
Ehf
ets homologous factor
chr11_-_83302586 1.513 ENSMUST00000176374.1
Pex12
peroxisomal biogenesis factor 12
chr8_+_72219726 1.505 ENSMUST00000003123.8
Fam32a
family with sequence similarity 32, member A
chrX_-_134276969 1.503 ENSMUST00000087541.5
ENSMUST00000087540.3
Trmt2b

TRM2 tRNA methyltransferase 2B

chr7_-_126695731 1.501 ENSMUST00000144897.1
Slx1b
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr9_-_65908676 1.500 ENSMUST00000119245.1
ENSMUST00000134338.1
ENSMUST00000179395.1
Trip4


thyroid hormone receptor interactor 4


chr8_+_109778863 1.484 ENSMUST00000034171.8
Ap1g1
adaptor protein complex AP-1, gamma 1 subunit
chr19_+_8920358 1.482 ENSMUST00000096243.5
B3gat3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr4_-_124851152 1.481 ENSMUST00000185036.1
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chr2_-_26933781 1.476 ENSMUST00000154651.1
ENSMUST00000015011.3
Surf4

surfeit gene 4

chr14_+_55591708 1.473 ENSMUST00000019443.8
Rnf31
ring finger protein 31

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 26.4 GO:0036102 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102)
2.8 2.8 GO:1905072 cardiac jelly development(GO:1905072)
2.2 6.7 GO:0010133 proline catabolic process to glutamate(GO:0010133)
1.6 9.6 GO:0018992 germ-line sex determination(GO:0018992)
1.5 4.5 GO:1990166 protein localization to site of double-strand break(GO:1990166)
1.5 8.9 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
1.4 7.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
1.4 23.7 GO:0060363 cranial suture morphogenesis(GO:0060363)
1.4 7.0 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
1.4 4.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
1.1 3.2 GO:0071423 alpha-ketoglutarate transport(GO:0015742) malate transport(GO:0015743) malate transmembrane transport(GO:0071423)
1.1 4.3 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
1.1 3.2 GO:0019045 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) establishment of viral latency(GO:0019043) latent virus replication(GO:0019045) release from viral latency(GO:0019046)
1.1 6.4 GO:0038161 prolactin signaling pathway(GO:0038161)
1.0 5.9 GO:1905894 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) response to tunicamycin(GO:1904576) cellular response to tunicamycin(GO:1904577) regulation of cellular response to thapsigargin(GO:1905891) negative regulation of cellular response to thapsigargin(GO:1905892) regulation of cellular response to tunicamycin(GO:1905894) negative regulation of cellular response to tunicamycin(GO:1905895)
0.9 2.7 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.9 1.8 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.9 20.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.9 3.4 GO:0038154 interleukin-11-mediated signaling pathway(GO:0038154)
0.8 3.1 GO:0090365 regulation of mRNA modification(GO:0090365)
0.8 3.1 GO:1905938 endomitotic cell cycle(GO:0007113) positive regulation of germ cell proliferation(GO:1905938) positive regulation of male germ cell proliferation(GO:2000256)
0.8 3.9 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.7 2.2 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.7 2.7 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.6 2.5 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.6 1.2 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.6 3.0 GO:0019086 late viral transcription(GO:0019086)
0.6 2.4 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.6 1.7 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.6 3.4 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.5 2.7 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.5 1.6 GO:0038129 ERBB3 signaling pathway(GO:0038129) regulation of protein localization to endoplasmic reticulum(GO:1905550) positive regulation of protein localization to endoplasmic reticulum(GO:1905552)
0.5 5.0 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.5 1.5 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.5 0.5 GO:0018307 enzyme active site formation(GO:0018307)
0.5 1.4 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.5 1.4 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.5 1.4 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.4 3.7 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.4 1.6 GO:0006624 vacuolar protein processing(GO:0006624)
0.4 2.9 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 1.6 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.4 6.8 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.4 2.8 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.4 1.9 GO:1990839 response to endothelin(GO:1990839)
0.4 1.8 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.4 4.8 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.4 1.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.4 1.8 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.3 4.5 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.3 1.7 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.3 1.4 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.3 4.4 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.3 1.0 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.3 2.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.3 1.0 GO:0071106 coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.3 2.3 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248)
0.3 1.0 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.3 1.5 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.3 2.1 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.3 1.5 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.3 2.7 GO:0008228 opsonization(GO:0008228)
0.3 4.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.3 0.6 GO:0045116 protein neddylation(GO:0045116)
0.3 0.9 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.3 0.9 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.3 2.0 GO:0048102 autophagic cell death(GO:0048102)
0.3 0.8 GO:0030167 proteoglycan catabolic process(GO:0030167) heparan sulfate proteoglycan catabolic process(GO:0030200)
0.3 2.0 GO:0061042 vascular wound healing(GO:0061042)
0.3 0.8 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.3 1.4 GO:0042637 catagen(GO:0042637)
0.3 2.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.3 1.4 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.3 0.8 GO:0016240 autophagosome membrane docking(GO:0016240)
0.3 0.8 GO:0090370 negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375) negative regulation of cholesterol efflux(GO:0090370)
0.3 0.5 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.2 1.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 1.7 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.2 4.2 GO:0030238 male sex determination(GO:0030238) Leydig cell differentiation(GO:0033327)
0.2 0.7 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.2 3.7 GO:0046415 urate metabolic process(GO:0046415)
0.2 2.1 GO:0006013 mannose metabolic process(GO:0006013)
0.2 1.4 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.2 2.3 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 2.0 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 4.2 GO:0050667 homocysteine metabolic process(GO:0050667)
0.2 1.1 GO:0071352 interleukin-2-mediated signaling pathway(GO:0038110) cellular response to interleukin-2(GO:0071352)
0.2 1.3 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.2 1.3 GO:0039019 pronephric nephron development(GO:0039019)
0.2 2.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 1.3 GO:0060023 soft palate development(GO:0060023)
0.2 1.7 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 3.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 1.5 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.2 3.3 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.2 1.7 GO:0009249 protein lipoylation(GO:0009249)
0.2 0.6 GO:1902277 pancreatic amylase secretion(GO:0036395) regulation of pancreatic amylase secretion(GO:1902276) negative regulation of pancreatic amylase secretion(GO:1902277)
0.2 1.2 GO:0010635 regulation of mitochondrial fusion(GO:0010635) positive regulation of mitochondrial fusion(GO:0010636)
0.2 2.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 1.0 GO:0002265 astrocyte activation involved in immune response(GO:0002265)
0.2 1.0 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2 0.6 GO:0097576 vacuole fusion(GO:0097576)
0.2 0.6 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 1.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 1.0 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 3.8 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 3.2 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.2 0.9 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.2 1.9 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.2 0.6 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2 1.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.2 0.5 GO:0044803 multi-organism membrane organization(GO:0044803)
0.2 1.2 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.2 2.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 0.7 GO:1903445 protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.2 1.2 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.2 0.5 GO:0060729 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) intestinal epithelial structure maintenance(GO:0060729)
0.2 1.4 GO:0031642 negative regulation of myelination(GO:0031642)
0.2 5.8 GO:0033198 response to ATP(GO:0033198)
0.2 2.7 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.2 2.0 GO:0070166 enamel mineralization(GO:0070166)
0.2 0.5 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.2 1.3 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.2 1.1 GO:0021539 subthalamus development(GO:0021539)
0.2 1.8 GO:0060346 bone trabecula formation(GO:0060346)
0.2 0.3 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1 18.9 GO:0055088 lipid homeostasis(GO:0055088)
0.1 4.5 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 1.4 GO:0001842 neural fold formation(GO:0001842)
0.1 1.2 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.0 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.9 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.7 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.1 0.7 GO:0097352 autophagosome maturation(GO:0097352)
0.1 0.5 GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 2.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 1.5 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.5 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 4.2 GO:0006110 regulation of glycolytic process(GO:0006110)
0.1 0.8 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 1.0 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 1.0 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.7 GO:0090383 phagosome acidification(GO:0090383)
0.1 1.4 GO:0030157 pancreatic juice secretion(GO:0030157)
0.1 0.2 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.7 GO:0071630 nuclear protein quality control by the ubiquitin-proteasome system(GO:0071630)
0.1 6.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.2 GO:0090045 positive regulation of deacetylase activity(GO:0090045)
0.1 1.6 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 1.5 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 1.5 GO:0071236 cellular response to antibiotic(GO:0071236)
0.1 0.6 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 1.2 GO:1904152 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) regulation of retrograde protein transport, ER to cytosol(GO:1904152) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 1.0 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 1.6 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.5 GO:2001205 negative regulation of bone development(GO:1903011) negative regulation of osteoclast development(GO:2001205)
0.1 3.3 GO:0071801 regulation of podosome assembly(GO:0071801)
0.1 0.2 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.6 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 4.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.3 GO:0018065 protein-cofactor linkage(GO:0018065)
0.1 1.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 1.4 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.1 0.4 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.1 0.3 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 1.5 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.1 1.5 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.1 1.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.9 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 1.9 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.1 3.3 GO:0006953 acute-phase response(GO:0006953)
0.1 3.3 GO:0006458 'de novo' protein folding(GO:0006458)
0.1 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.6 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 0.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.2 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791)
0.1 0.7 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.1 1.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 0.7 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1 1.8 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.1 3.4 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 1.1 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.2 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 2.7 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.1 0.2 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.1 0.6 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.8 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.8 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 2.8 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.2 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 1.3 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.1 0.7 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.5 GO:1901033 positive regulation of response to reactive oxygen species(GO:1901033) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.1 1.0 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.5 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 1.3 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 0.3 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.6 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629)
0.0 0.9 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 0.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.4 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0 0.7 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 1.1 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 1.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.6 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 1.9 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.7 GO:0006465 signal peptide processing(GO:0006465)
0.0 1.1 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.5 GO:0070914 UV-damage excision repair(GO:0070914) UV-damage excision repair, DNA incision(GO:1990731)
0.0 2.3 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.8 GO:0034389 lipid particle organization(GO:0034389)
0.0 1.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.6 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 2.5 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.9 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 1.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 2.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.9 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.0 0.7 GO:0001881 receptor recycling(GO:0001881)
0.0 0.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.0 0.4 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.4 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.9 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 1.2 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 1.1 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.2 GO:0009146 purine nucleoside triphosphate catabolic process(GO:0009146)
0.0 3.9 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.3 GO:0044804 autophagy of nucleus(GO:0044804)
0.0 0.6 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.0 3.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 1.0 GO:1901998 toxin transport(GO:1901998)
0.0 0.6 GO:0005980 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.7 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.3 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.7 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 1.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 1.5 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.4 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.9 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 1.4 GO:0022900 electron transport chain(GO:0022900)
0.0 0.2 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.6 GO:0009060 aerobic respiration(GO:0009060)
0.0 3.1 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 1.1 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.6 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.0 0.2 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 1.0 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.5 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) interstrand cross-link repair(GO:0036297)
0.0 0.2 GO:0021819 layer formation in cerebral cortex(GO:0021819) radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.8 GO:0060976 coronary vasculature development(GO:0060976)
0.0 1.2 GO:0007030 Golgi organization(GO:0007030)
0.0 0.8 GO:0016525 negative regulation of angiogenesis(GO:0016525) negative regulation of blood vessel morphogenesis(GO:2000181)
0.0 0.1 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 1.2 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 1.6 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.7 GO:0030433 ubiquitin-dependent ERAD pathway(GO:0030433)
0.0 1.9 GO:0042098 T cell proliferation(GO:0042098)
0.0 0.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:0051785 positive regulation of mitotic nuclear division(GO:0045840) positive regulation of nuclear division(GO:0051785)
0.0 0.4 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 1.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.9 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.5 GO:0006487 protein N-linked glycosylation(GO:0006487)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 23.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
1.4 4.1 GO:0061825 podosome core(GO:0061825)
1.2 1.2 GO:0045277 respiratory chain complex IV(GO:0045277) respiratory chain complex(GO:0098803)
1.0 9.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.5 0.5 GO:0019034 viral replication complex(GO:0019034)
0.5 3.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.5 2.7 GO:0032437 cuticular plate(GO:0032437)
0.5 5.9 GO:0097418 neurofibrillary tangle(GO:0097418)
0.4 1.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.4 4.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.4 1.2 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.4 1.5 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.4 1.5 GO:0099053 activating signal cointegrator 1 complex(GO:0099053)
0.4 4.1 GO:0032584 growth cone membrane(GO:0032584)
0.4 1.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.3 1.4 GO:0070552 BRISC complex(GO:0070552)
0.3 0.6 GO:0090725 peripheral region of growth cone(GO:0090725)
0.3 1.5 GO:0044194 cytolytic granule(GO:0044194)
0.3 1.5 GO:0071797 LUBAC complex(GO:0071797)
0.3 1.8 GO:0000235 astral microtubule(GO:0000235)
0.3 0.9 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.3 1.9 GO:0070695 FHF complex(GO:0070695)
0.3 0.8 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.3 1.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 2.8 GO:0005579 membrane attack complex(GO:0005579)
0.3 1.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 1.0 GO:0035339 SPOTS complex(GO:0035339)
0.2 2.3 GO:0097433 dense body(GO:0097433)
0.2 1.8 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 1.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.2 5.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 1.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 2.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.2 1.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 2.0 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 2.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 0.6 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.2 0.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 0.7 GO:0032280 symmetric synapse(GO:0032280)
0.2 0.5 GO:0000814 ESCRT II complex(GO:0000814)
0.2 3.5 GO:0000421 autophagosome membrane(GO:0000421)
0.2 0.7 GO:1990462 omegasome(GO:1990462)
0.2 3.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 1.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 6.6 GO:0002102 podosome(GO:0002102)
0.1 3.1 GO:0032433 filopodium tip(GO:0032433)
0.1 1.6 GO:0031931 TORC1 complex(GO:0031931)
0.1 4.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.4 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.5 GO:0140007 KICSTOR complex(GO:0140007)
0.1 0.6 GO:0030897 HOPS complex(GO:0030897)
0.1 3.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 6.5 GO:0031901 early endosome membrane(GO:0031901)
0.1 1.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 6.8 GO:0000791 euchromatin(GO:0000791)
0.1 0.7 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 1.4 GO:0048188 NURF complex(GO:0016589) Set1C/COMPASS complex(GO:0048188)
0.1 0.7 GO:0090724 central region of growth cone(GO:0090724)
0.1 4.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 4.5 GO:0090734 site of double-strand break(GO:0035861) site of DNA damage(GO:0090734)
0.1 0.6 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 3.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.9 GO:0089701 U2AF(GO:0089701)
0.1 0.9 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 2.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.7 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.7 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.3 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 1.0 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 4.2 GO:0005776 autophagosome(GO:0005776)
0.1 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 1.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.6 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.9 GO:0033391 chromatoid body(GO:0033391)
0.1 0.8 GO:0017119 Golgi transport complex(GO:0017119)
0.1 3.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.3 GO:0097441 basilar dendrite(GO:0097441)
0.1 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 3.1 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 2.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 4.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.0 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.6 GO:0005869 dynactin complex(GO:0005869)
0.0 34.0 GO:0016604 nuclear body(GO:0016604)
0.0 4.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 17.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.3 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.5 GO:0031201 SNARE complex(GO:0031201)
0.0 1.2 GO:0016592 mediator complex(GO:0016592) core mediator complex(GO:0070847)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 3.8 GO:0001650 fibrillar center(GO:0001650)
0.0 0.8 GO:0045095 keratin filament(GO:0045095)
0.0 2.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 2.8 GO:0043204 perikaryon(GO:0043204)
0.0 1.4 GO:0032421 stereocilium(GO:0032420) stereocilium bundle(GO:0032421)
0.0 0.5 GO:1990204 oxidoreductase complex(GO:1990204)
0.0 0.6 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.6 GO:0016234 inclusion body(GO:0016234)
0.0 0.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 5.9 GO:0005635 nuclear envelope(GO:0005635)
0.0 8.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.1 GO:0071439 clathrin complex(GO:0071439)
0.0 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.2 GO:0005882 intermediate filament(GO:0005882)
0.0 0.8 GO:0005811 lipid droplet(GO:0005811)
0.0 0.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 3.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 8.0 GO:0005929 cilium(GO:0005929) intraciliary transport particle(GO:0030990)
0.0 18.5 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 11.8 GO:0005739 mitochondrion(GO:0005739)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
8.8 26.4 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
1.4 7.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
1.3 6.4 GO:0004925 prolactin receptor activity(GO:0004925)
1.2 3.5 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
1.1 3.2 GO:0015140 malate transmembrane transporter activity(GO:0015140)
1.1 3.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.1 4.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
1.0 3.1 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
1.0 1.0 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.9 3.4 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.8 2.5 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.7 5.1 GO:0004046 aminoacylase activity(GO:0004046)
0.7 2.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.7 3.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.6 3.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.6 4.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.6 1.8 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.6 3.4 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.6 1.7 GO:0019972 interleukin-12 binding(GO:0019972)
0.6 1.7 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.6 2.8 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.6 1.7 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.6 2.2 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.5 1.6 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.5 2.6 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.5 4.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.5 2.0 GO:0097003 adipokinetic hormone receptor activity(GO:0097003) adipokinetic hormone binding(GO:0097004)
0.5 1.4 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
0.5 1.4 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.5 1.4 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.4 7.0 GO:0044548 S100 protein binding(GO:0044548)
0.4 2.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.4 5.0 GO:0008430 selenium binding(GO:0008430)
0.4 2.8 GO:0005534 galactose binding(GO:0005534)
0.4 1.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.4 1.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.4 1.4 GO:0031699 beta-3 adrenergic receptor binding(GO:0031699)
0.3 1.4 GO:0030984 kininogen binding(GO:0030984)
0.3 1.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3 1.0 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.3 2.3 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.3 1.0 GO:0004534 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534)
0.3 0.9 GO:0016748 succinyltransferase activity(GO:0016748)
0.3 2.8 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.3 1.5 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.3 3.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.3 1.5 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.3 10.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.3 3.9 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.3 4.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3 4.1 GO:0070513 death domain binding(GO:0070513)
0.3 1.6 GO:0005047 signal recognition particle binding(GO:0005047)
0.3 1.0 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 3.7 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 3.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 1.7 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.2 2.3 GO:0004462 hydroxyacylglutathione hydrolase activity(GO:0004416) lactoylglutathione lyase activity(GO:0004462)
0.2 2.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 5.2 GO:0051787 misfolded protein binding(GO:0051787)
0.2 0.9 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.2 1.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 1.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 1.8 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 7.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 0.6 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.2 1.3 GO:0030172 troponin C binding(GO:0030172)
0.2 2.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 2.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 1.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.2 1.2 GO:0004673 protein histidine kinase activity(GO:0004673)
0.2 1.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) phosphatidylinositol-3,5-bisphosphate phosphatase activity(GO:0106018)
0.2 6.7 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.2 1.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 3.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 1.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 4.5 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.2 4.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.7 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 1.8 GO:0017166 vinculin binding(GO:0017166)
0.1 2.1 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 1.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 1.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.0 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.5 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 1.5 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.1 2.6 GO:0005537 mannose binding(GO:0005537)
0.1 1.5 GO:0019841 retinol binding(GO:0019841)
0.1 0.6 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 4.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.8 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 1.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 2.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) tumor necrosis factor binding(GO:0043120)
0.1 0.5 GO:0061605 thiosulfate sulfurtransferase activity(GO:0004792) molybdopterin-synthase sulfurtransferase activity(GO:0061604) molybdopterin-synthase adenylyltransferase activity(GO:0061605)
0.1 3.5 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 3.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 2.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 2.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 3.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 11.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.2 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 0.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.5 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.2 GO:0001003 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.1 3.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 0.7 GO:0051400 BH domain binding(GO:0051400)
0.1 1.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 4.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 1.6 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 1.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.6 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.9 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 20.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.5 GO:0022829 wide pore channel activity(GO:0022829)
0.1 0.8 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 3.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 7.3 GO:0020037 heme binding(GO:0020037)
0.1 0.5 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 3.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.8 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.1 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 2.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 1.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.0 1.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 2.9 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 7.5 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0019961 interferon binding(GO:0019961)
0.0 4.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 7.4 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 3.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.3 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 3.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 3.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 1.5 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 1.2 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.5 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 1.9 GO:0008083 growth factor activity(GO:0008083)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 1.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 8.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 5.9 GO:0005525 GTP binding(GO:0005525)
0.0 0.1 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 2.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.5 GO:0003777 microtubule motor activity(GO:0003777)
0.0 2.4 GO:0015631 tubulin binding(GO:0015631)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.8 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.7 GO:0051087 chaperone binding(GO:0051087)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.2 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.3 5.7 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.2 6.4 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 16.8 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.2 3.2 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.2 4.1 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.5 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 6.6 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 3.2 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 5.5 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 1.8 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 6.3 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 13.7 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.1 2.6 PID_ARF_3PATHWAY Arf1 pathway
0.1 1.8 PID_IFNG_PATHWAY IFN-gamma pathway
0.1 8.4 PID_E2F_PATHWAY E2F transcription factor network
0.1 7.1 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 4.4 PID_INSULIN_PATHWAY Insulin Pathway
0.1 2.8 PID_ALK1_PATHWAY ALK1 signaling events
0.1 1.4 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.1 1.7 PID_IL27_PATHWAY IL27-mediated signaling events
0.1 1.3 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.1 1.5 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 4.8 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 0.3 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.1 2.5 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 3.7 PID_AP1_PATHWAY AP-1 transcription factor network
0.1 3.2 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.0 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.5 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.9 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.6 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.6 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID_EPO_PATHWAY EPO signaling pathway
0.0 1.1 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.3 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.2 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 0.7 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.9 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID_ATM_PATHWAY ATM pathway
0.0 2.1 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 3.9 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.1 PID_MYC_PATHWAY C-MYC pathway
0.0 0.7 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.3 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.6 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.1 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.4 4.0 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.4 7.0 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.4 5.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.3 6.7 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.3 6.0 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.3 4.5 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.3 3.7 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.3 4.2 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 3.7 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 2.7 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 2.8 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 5.0 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.2 2.0 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 3.7 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 2.1 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.2 4.5 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.1 2.1 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 9.2 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.3 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.3 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway
0.1 2.3 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.0 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 3.3 REACTOME_KINESINS Genes involved in Kinesins
0.1 1.4 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.1 0.8 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 1.9 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 2.0 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.8 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 2.0 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 2.8 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.1 0.6 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.5 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.1 3.2 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.4 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 0.8 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.0 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 5.1 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.8 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 1.1 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.6 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.2 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.6 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 3.0 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 1.4 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.1 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.9 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.2 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 3.9 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 1.1 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.7 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.0 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 3.5 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.8 REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.7 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.9 REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0 1.3 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.1 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.2 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.7 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 2.7 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives