Motif ID: Etv6

Z-value: 1.253


Transcription factors associated with Etv6:

Gene SymbolEntrez IDGene Name
Etv6 ENSMUSG00000030199.10 Etv6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Etv6mm10_v2_chr6_+_134035691_134035717-0.812.3e-09Click!


Activity profile for motif Etv6.

activity profile for motif Etv6


Sorted Z-values histogram for motif Etv6

Sorted Z-values for motif Etv6



Network of associatons between targets according to the STRING database.



First level regulatory network of Etv6

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_155517948 3.360 ENSMUST00000029135.8
ENSMUST00000065973.2
ENSMUST00000103142.5
Acss2


acyl-CoA synthetase short-chain family member 2


chr3_-_89764581 3.061 ENSMUST00000029562.3
Chrnb2
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr2_-_130424242 2.922 ENSMUST00000089581.4
Pced1a
PC-esterase domain containing 1A
chr1_+_58586381 2.612 ENSMUST00000027193.8
Ndufb3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3
chr5_+_147860615 2.366 ENSMUST00000031654.6
Pomp
proteasome maturation protein
chr11_-_20112876 2.201 ENSMUST00000000137.7
Actr2
ARP2 actin-related protein 2
chr15_+_58933774 2.200 ENSMUST00000022980.3
Ndufb9
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9
chr16_+_13903152 2.162 ENSMUST00000128757.1
Mpv17l
Mpv17 transgene, kidney disease mutant-like
chr11_+_120098910 2.085 ENSMUST00000106223.2
1810043H04Rik
RIKEN cDNA 1810043H04 gene
chr3_-_94886945 1.985 ENSMUST00000005923.6
Psmb4
proteasome (prosome, macropain) subunit, beta type 4
chr14_-_101640434 1.981 ENSMUST00000168587.1
Commd6
COMM domain containing 6
chr10_+_77864623 1.956 ENSMUST00000092366.2
Tspear
thrombospondin type laminin G domain and EAR repeats
chr11_-_96916448 1.934 ENSMUST00000103152.4
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr4_+_118409331 1.931 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chr14_-_101640670 1.928 ENSMUST00000100339.2
Commd6
COMM domain containing 6
chr11_-_96916366 1.926 ENSMUST00000144731.1
ENSMUST00000127048.1
Cdk5rap3

CDK5 regulatory subunit associated protein 3

chr1_+_167308649 1.851 ENSMUST00000097473.4
Tmco1
transmembrane and coiled-coil domains 1
chr11_+_115163333 1.839 ENSMUST00000021077.3
Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr1_-_179546261 1.802 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr10_-_67285180 1.767 ENSMUST00000159002.1
ENSMUST00000077839.6
Nrbf2

nuclear receptor binding factor 2

chr16_+_64851991 1.765 ENSMUST00000067744.7
Cggbp1
CGG triplet repeat binding protein 1
chr4_-_98383232 1.744 ENSMUST00000143116.1
ENSMUST00000030292.5
ENSMUST00000102793.4
Tm2d1


TM2 domain containing 1


chr19_-_45006385 1.739 ENSMUST00000097715.2
Mrpl43
mitochondrial ribosomal protein L43
chr13_-_4279420 1.735 ENSMUST00000021632.3
Akr1c12
aldo-keto reductase family 1, member C12
chr14_+_51884842 1.726 ENSMUST00000047899.6
ENSMUST00000164902.1
Mettl17

methyltransferase like 17

chr5_-_149636164 1.701 ENSMUST00000076410.4
Hsph1
heat shock 105kDa/110kDa protein 1
chr7_-_126584578 1.698 ENSMUST00000150311.1
Cln3
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr17_+_46711459 1.657 ENSMUST00000002840.8
Pex6
peroxisomal biogenesis factor 6
chr13_+_4191163 1.656 ENSMUST00000021634.2
Akr1c13
aldo-keto reductase family 1, member C13
chr9_+_46273064 1.644 ENSMUST00000156440.1
ENSMUST00000034583.6
ENSMUST00000114552.3
Zfp259


zinc finger protein 259


chr2_-_168230575 1.643 ENSMUST00000109193.1
Dpm1
dolichol-phosphate (beta-D) mannosyltransferase 1
chr11_+_58330744 1.621 ENSMUST00000073128.6
Sh3bp5l
SH3 binding domain protein 5 like
chr6_-_35539765 1.621 ENSMUST00000031866.5
Mtpn
myotrophin
chr17_+_46110982 1.617 ENSMUST00000024763.3
ENSMUST00000123646.1
Mrps18a

mitochondrial ribosomal protein S18A

chr7_-_67645195 1.590 ENSMUST00000032775.5
ENSMUST00000053950.2
Lrrc28

leucine rich repeat containing 28

chr1_+_156035392 1.577 ENSMUST00000111757.3
Tor1aip2
torsin A interacting protein 2
chr11_-_120457936 1.554 ENSMUST00000137632.1
ENSMUST00000044007.2
Oxld1

oxidoreductase like domain containing 1

chr19_-_28963863 1.552 ENSMUST00000161813.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr1_+_4807823 1.546 ENSMUST00000027036.4
ENSMUST00000119612.2
ENSMUST00000137887.1
ENSMUST00000115529.1
ENSMUST00000150971.1
Lypla1




lysophospholipase 1




chr11_-_97150025 1.544 ENSMUST00000118375.1
Tbkbp1
TBK1 binding protein 1
chr11_-_96916407 1.543 ENSMUST00000130774.1
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr2_-_90904827 1.524 ENSMUST00000005647.3
Ndufs3
NADH dehydrogenase (ubiquinone) Fe-S protein 3
chr2_-_168230353 1.501 ENSMUST00000154111.1
Dpm1
dolichol-phosphate (beta-D) mannosyltransferase 1
chr1_-_36244245 1.497 ENSMUST00000046875.7
Uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr12_-_44210061 1.495 ENSMUST00000015049.3
Dnajb9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr3_-_95871367 1.459 ENSMUST00000142437.1
ENSMUST00000067298.4
Mrps21

mitochondrial ribosomal protein S21

chr4_+_48279794 1.450 ENSMUST00000030029.3
Invs
inversin
chr8_-_70139197 1.439 ENSMUST00000075724.7
Rfxank
regulatory factor X-associated ankyrin-containing protein
chr14_+_55591708 1.410 ENSMUST00000019443.8
Rnf31
ring finger protein 31
chr5_-_139826407 1.406 ENSMUST00000182839.1
Gm26938
predicted gene, 26938
chrX_-_169320273 1.402 ENSMUST00000033717.2
ENSMUST00000112115.1
Hccs

holocytochrome c synthetase

chr5_-_149636331 1.401 ENSMUST00000074846.7
ENSMUST00000110498.1
ENSMUST00000127977.1
ENSMUST00000132412.1
Hsph1



heat shock 105kDa/110kDa protein 1



chr8_-_107056650 1.399 ENSMUST00000034391.3
ENSMUST00000095517.5
Cog8

component of oligomeric golgi complex 8

chr7_+_112427706 1.390 ENSMUST00000033030.7
Parva
parvin, alpha
chr14_+_51884982 1.372 ENSMUST00000167984.1
Mettl17
methyltransferase like 17
chr19_-_6084873 1.349 ENSMUST00000160977.1
ENSMUST00000159859.1
Zfpl1

zinc finger like protein 1

chr10_+_128805652 1.347 ENSMUST00000026410.1
Dnajc14
DnaJ (Hsp40) homolog, subfamily C, member 14
chr14_+_47298260 1.345 ENSMUST00000166743.1
Mapk1ip1l
mitogen-activated protein kinase 1 interacting protein 1-like
chr19_+_8871636 1.343 ENSMUST00000096255.5
Ubxn1
UBX domain protein 1
chr10_+_80172934 1.333 ENSMUST00000041882.6
1600002K03Rik
RIKEN cDNA 1600002K03 gene
chr19_+_3282901 1.331 ENSMUST00000025745.3
ENSMUST00000025743.6
Mrpl21

mitochondrial ribosomal protein L21

chr9_+_107563246 1.317 ENSMUST00000010198.3
Tusc2
tumor suppressor candidate 2
chr8_-_124863008 1.317 ENSMUST00000034465.7
2810004N23Rik
RIKEN cDNA 2810004N23 gene
chr19_-_6084679 1.311 ENSMUST00000161548.1
Zfpl1
zinc finger like protein 1
chr2_-_94010807 1.297 ENSMUST00000111240.1
Alkbh3
alkB, alkylation repair homolog 3 (E. coli)
chr10_-_31609184 1.295 ENSMUST00000081989.6
Rnf217
ring finger protein 217
chr3_-_88425094 1.274 ENSMUST00000168755.1
ENSMUST00000057935.6
Slc25a44

solute carrier family 25, member 44

chr7_-_80947499 1.273 ENSMUST00000120285.1
Sec11a
SEC11 homolog A (S. cerevisiae)
chr1_+_74601548 1.270 ENSMUST00000087186.4
Stk36
serine/threonine kinase 36
chr15_-_58933688 1.259 ENSMUST00000110155.1
Tatdn1
TatD DNase domain containing 1
chr7_-_105744312 1.258 ENSMUST00000141116.1
Taf10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr2_-_132815978 1.245 ENSMUST00000039554.6
Trmt6
tRNA methyltransferase 6
chr9_-_79759849 1.242 ENSMUST00000034881.6
Cox7a2
cytochrome c oxidase subunit VIIa 2
chr1_+_4808237 1.232 ENSMUST00000131119.1
Lypla1
lysophospholipase 1
chr2_-_130424673 1.231 ENSMUST00000110277.1
Pced1a
PC-esterase domain containing 1A
chr15_+_76331288 1.220 ENSMUST00000172281.1
Gpaa1
GPI anchor attachment protein 1
chrX_-_168673828 1.215 ENSMUST00000033725.9
ENSMUST00000112137.1
Msl3

male-specific lethal 3 homolog (Drosophila)

chr19_-_6084941 1.205 ENSMUST00000025707.2
ENSMUST00000160712.1
Zfpl1

zinc finger like protein 1

chr19_+_8920358 1.186 ENSMUST00000096243.5
B3gat3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr12_-_81532840 1.181 ENSMUST00000166664.1
ENSMUST00000164386.1
ENSMUST00000169158.1
ENSMUST00000164431.1
ENSMUST00000163402.1
Gm20498

Synj2bp


predicted gene 20498

synaptojanin 2 binding protein


chr7_+_44850393 1.172 ENSMUST00000136232.1
Akt1s1
AKT1 substrate 1 (proline-rich)
chr19_+_8871512 1.166 ENSMUST00000166407.1
Ubxn1
UBX domain protein 1
chr2_+_132686931 1.159 ENSMUST00000061891.4
1110034G24Rik
RIKEN cDNA 1110034G24 gene
chrX_+_7884321 1.159 ENSMUST00000096514.3
ENSMUST00000123277.1
Slc35a2

solute carrier family 35 (UDP-galactose transporter), member A2

chr5_-_115348953 1.129 ENSMUST00000040154.8
Cox6a1
cytochrome c oxidase subunit VIa polypeptide 1
chr16_+_3872368 1.104 ENSMUST00000151988.1
Naa60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr19_+_28963892 1.101 ENSMUST00000045674.2
Ppapdc2
phosphatidic acid phosphatase type 2 domain containing 2
chr2_-_10080322 1.098 ENSMUST00000145530.1
ENSMUST00000026887.7
ENSMUST00000114896.1
ENSMUST00000114897.2
Atp5c1



ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1



chr5_-_139826837 1.096 ENSMUST00000182602.1
ENSMUST00000031531.7
Psmg3

proteasome (prosome, macropain) assembly chaperone 3

chr2_+_39008076 1.091 ENSMUST00000112862.1
ENSMUST00000090993.5
Arpc5l

actin related protein 2/3 complex, subunit 5-like

chr4_+_107178399 1.090 ENSMUST00000030361.4
ENSMUST00000128123.1
ENSMUST00000106753.1
Tmem59


transmembrane protein 59


chr19_-_45660312 1.084 ENSMUST00000046869.4
Fbxw4
F-box and WD-40 domain protein 4
chrX_-_141725181 1.069 ENSMUST00000067841.7
Irs4
insulin receptor substrate 4
chr7_-_46919915 1.062 ENSMUST00000143413.1
ENSMUST00000014546.8
Tsg101

tumor susceptibility gene 101

chrX_+_7884022 1.032 ENSMUST00000115660.4
Slc35a2
solute carrier family 35 (UDP-galactose transporter), member A2
chr17_+_35121455 1.026 ENSMUST00000173380.1
ENSMUST00000173043.3
ENSMUST00000165306.2
Gpank1


G patch domain and ankyrin repeats 1


chr15_-_99474696 1.014 ENSMUST00000040313.4
Bcdin3d
BCDIN3 domain containing
chr15_-_57892358 1.014 ENSMUST00000022993.5
Derl1
Der1-like domain family, member 1
chr11_-_120624973 1.001 ENSMUST00000106183.2
ENSMUST00000080202.5
Sirt7

sirtuin 7

chr2_-_127208274 0.994 ENSMUST00000056146.1
1810024B03Rik
RIKEN cDNA 1810024B03 gene
chr15_+_9140527 0.989 ENSMUST00000090380.4
Lmbrd2
LMBR1 domain containing 2
chr7_+_127233044 0.971 ENSMUST00000106312.3
Zfp553
zinc finger protein 553
chr16_-_87432597 0.962 ENSMUST00000039449.7
Ltn1
listerin E3 ubiquitin protein ligase 1
chr6_-_113377866 0.962 ENSMUST00000032410.7
Tada3
transcriptional adaptor 3
chr18_+_53862087 0.959 ENSMUST00000069597.6
Csnk1g3
casein kinase 1, gamma 3
chr11_+_106256140 0.953 ENSMUST00000021049.2
Psmc5
protease (prosome, macropain) 26S subunit, ATPase 5
chr4_-_40948196 0.943 ENSMUST00000030125.4
ENSMUST00000108089.1
Bag1

BCL2-associated athanogene 1

chr13_+_46669517 0.941 ENSMUST00000099547.3
C78339
expressed sequence C78339
chr19_+_6996114 0.939 ENSMUST00000088223.5
Trpt1
tRNA phosphotransferase 1
chr7_-_80947765 0.935 ENSMUST00000026818.5
ENSMUST00000117383.1
ENSMUST00000119980.1
Sec11a


SEC11 homolog A (S. cerevisiae)


chr4_-_48279544 0.929 ENSMUST00000030028.4
Erp44
endoplasmic reticulum protein 44
chr11_-_79962374 0.916 ENSMUST00000108241.1
ENSMUST00000043152.5
Utp6

UTP6, small subunit (SSU) processome component, homolog (yeast)

chr7_-_13034722 0.915 ENSMUST00000005711.4
Chmp2a
charged multivesicular body protein 2A
chr4_-_116017854 0.915 ENSMUST00000049095.5
Faah
fatty acid amide hydrolase
chr6_-_124965403 0.893 ENSMUST00000129446.1
ENSMUST00000032220.8
Cops7a

COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)

chr4_+_31964081 0.892 ENSMUST00000037607.4
ENSMUST00000080933.6
ENSMUST00000108183.1
ENSMUST00000108184.2
Map3k7



mitogen-activated protein kinase kinase kinase 7



chr14_-_18331855 0.884 ENSMUST00000022296.6
Ube2e1
ubiquitin-conjugating enzyme E2E 1
chr10_+_79669410 0.883 ENSMUST00000020552.5
Tpgs1
tubulin polyglutamylase complex subunit 1
chr7_+_80261202 0.882 ENSMUST00000117989.1
Ngrn
neugrin, neurite outgrowth associated
chrX_+_7884244 0.878 ENSMUST00000115663.3
Slc35a2
solute carrier family 35 (UDP-galactose transporter), member A2
chr11_-_120467414 0.871 ENSMUST00000076921.6
Arl16
ADP-ribosylation factor-like 16
chr11_+_61653259 0.871 ENSMUST00000004959.2
Grap
GRB2-related adaptor protein
chr2_-_84715160 0.865 ENSMUST00000035840.5
Zdhhc5
zinc finger, DHHC domain containing 5
chr11_-_77078404 0.864 ENSMUST00000102494.1
Ccdc55
coiled-coil domain containing 55
chr3_+_90052814 0.860 ENSMUST00000160640.1
ENSMUST00000029552.6
ENSMUST00000162114.1
ENSMUST00000068798.6
4933434E20Rik



RIKEN cDNA 4933434E20 gene



chr9_-_57645561 0.856 ENSMUST00000034863.6
Csk
c-src tyrosine kinase
chr11_-_120098673 0.854 ENSMUST00000093901.5
ENSMUST00000026442.4
ENSMUST00000106225.3
Enthd2


ENTH domain containing 2


chr4_-_124851152 0.850 ENSMUST00000185036.1
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chr17_-_15498263 0.850 ENSMUST00000014913.9
Psmb1
proteasome (prosome, macropain) subunit, beta type 1
chr7_+_81762925 0.848 ENSMUST00000042166.4
Fam103a1
family with sequence similarity 103, member A1
chr11_+_88204396 0.845 ENSMUST00000118784.1
ENSMUST00000139170.1
ENSMUST00000107915.3
ENSMUST00000144070.1
Mrps23



mitochondrial ribosomal protein S23



chr2_-_94010729 0.844 ENSMUST00000040005.6
ENSMUST00000126378.1
Alkbh3

alkB, alkylation repair homolog 3 (E. coli)

chr4_-_119173849 0.841 ENSMUST00000052715.4
ENSMUST00000179290.1
ENSMUST00000154226.1
Zfp691


zinc finger protein 691


chr5_-_145140238 0.839 ENSMUST00000031627.8
Pdap1
PDGFA associated protein 1
chr6_+_125009665 0.836 ENSMUST00000046064.10
ENSMUST00000152752.1
ENSMUST00000088308.3
ENSMUST00000112425.1
ENSMUST00000084275.5
Zfp384




zinc finger protein 384




chr17_-_35121173 0.831 ENSMUST00000174024.1
Csnk2b
casein kinase 2, beta polypeptide
chr4_+_124802543 0.824 ENSMUST00000138807.1
ENSMUST00000030723.2
ENSMUST00000175875.1
Mtf1


metal response element binding transcription factor 1


chr5_+_145140362 0.823 ENSMUST00000162594.1
ENSMUST00000162308.1
ENSMUST00000159018.1
ENSMUST00000160075.1
Bud31



BUD31 homolog (yeast)



chr6_-_88518760 0.822 ENSMUST00000032168.5
Sec61a1
Sec61 alpha 1 subunit (S. cerevisiae)
chr11_+_58330712 0.818 ENSMUST00000116376.2
Sh3bp5l
SH3 binding domain protein 5 like
chr7_+_127233227 0.811 ENSMUST00000056232.6
Zfp553
zinc finger protein 553
chr9_+_20644792 0.809 ENSMUST00000162303.1
ENSMUST00000161486.1
Ubl5

ubiquitin-like 5

chr17_-_35121213 0.806 ENSMUST00000025246.6
Csnk2b
casein kinase 2, beta polypeptide
chr11_+_118428493 0.796 ENSMUST00000017590.2
C1qtnf1
C1q and tumor necrosis factor related protein 1
chr11_-_50210765 0.796 ENSMUST00000143379.1
ENSMUST00000015981.5
ENSMUST00000102774.4
Sqstm1


sequestosome 1


chrX_+_144317799 0.796 ENSMUST00000070801.4
Alg13
asparagine-linked glycosylation 13
chr11_+_94653767 0.794 ENSMUST00000025278.7
Mrpl27
mitochondrial ribosomal protein L27
chr15_+_76331231 0.794 ENSMUST00000023221.6
Gpaa1
GPI anchor attachment protein 1
chr7_+_5080214 0.790 ENSMUST00000098845.3
ENSMUST00000146317.1
ENSMUST00000153169.1
ENSMUST00000045277.6
Epn1



epsin 1



chr5_-_31220491 0.787 ENSMUST00000031032.7
Ppm1g
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
chr15_+_5185700 0.783 ENSMUST00000081640.5
Ttc33
tetratricopeptide repeat domain 33
chr19_+_45006475 0.780 ENSMUST00000026227.2
Peo1
progressive external ophthalmoplegia 1 (human)
chr17_-_35121030 0.778 ENSMUST00000174306.1
Csnk2b
casein kinase 2, beta polypeptide
chr11_+_5955693 0.771 ENSMUST00000002818.8
Ykt6
YKT6 homolog (S. Cerevisiae)
chr15_+_5185519 0.768 ENSMUST00000118193.1
ENSMUST00000022751.8
Ttc33

tetratricopeptide repeat domain 33

chr1_+_74601441 0.764 ENSMUST00000087183.4
ENSMUST00000148456.1
ENSMUST00000113694.1
Stk36


serine/threonine kinase 36


chr6_-_113377712 0.750 ENSMUST00000113107.1
ENSMUST00000113106.1
Tada3

transcriptional adaptor 3

chr1_-_58586191 0.748 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
Fam126b



family with sequence similarity 126, member B



chr2_+_152226839 0.745 ENSMUST00000099224.3
ENSMUST00000124791.1
ENSMUST00000133119.1
Csnk2a1


casein kinase 2, alpha 1 polypeptide


chr2_+_160888101 0.742 ENSMUST00000109455.2
ENSMUST00000040872.6
Lpin3

lipin 3

chr8_-_84147858 0.737 ENSMUST00000117424.2
ENSMUST00000040383.8
Cc2d1a

coiled-coil and C2 domain containing 1A

chr9_+_20581296 0.737 ENSMUST00000115557.2
Zfp846
zinc finger protein 846
chr9_+_20644851 0.737 ENSMUST00000161882.1
Ubl5
ubiquitin-like 5
chr17_-_35121423 0.736 ENSMUST00000173114.1
Csnk2b
casein kinase 2, beta polypeptide
chr2_+_160888156 0.736 ENSMUST00000109457.2
Lpin3
lipin 3
chrX_-_94212685 0.730 ENSMUST00000050328.8
Eif2s3x
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked
chr14_-_70520254 0.729 ENSMUST00000022693.7
Bmp1
bone morphogenetic protein 1
chr19_+_5366764 0.729 ENSMUST00000025759.7
Eif1ad
eukaryotic translation initiation factor 1A domain containing
chr5_-_135744206 0.712 ENSMUST00000153399.1
ENSMUST00000043378.2
Tmem120a

transmembrane protein 120A

chr4_-_118409219 0.711 ENSMUST00000075406.5
Szt2
seizure threshold 2
chr19_+_46599081 0.707 ENSMUST00000138302.2
ENSMUST00000099376.4
Wbp1l

WW domain binding protein 1 like

chr4_-_155086271 0.706 ENSMUST00000030914.3
Rer1
RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)
chr11_-_16508069 0.705 ENSMUST00000109641.1
Sec61g
SEC61, gamma subunit
chr2_+_130424321 0.699 ENSMUST00000128994.1
ENSMUST00000028900.9
Vps16

vacuolar protein sorting 16 (yeast)

chrX_+_42068398 0.697 ENSMUST00000115095.2
Xiap
X-linked inhibitor of apoptosis
chr12_-_78861636 0.694 ENSMUST00000021536.7
Atp6v1d
ATPase, H+ transporting, lysosomal V1 subunit D
chr4_+_40948401 0.689 ENSMUST00000030128.5
Chmp5
charged multivesicular body protein 5
chr4_-_119174178 0.683 ENSMUST00000106355.3
Zfp691
zinc finger protein 691
chr1_+_91250482 0.683 ENSMUST00000171112.1
Ube2f
ubiquitin-conjugating enzyme E2F (putative)
chr12_+_85110833 0.683 ENSMUST00000053811.8
Dlst
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr11_+_88204380 0.681 ENSMUST00000024486.7
Mrps23
mitochondrial ribosomal protein S23
chr11_+_87592145 0.677 ENSMUST00000103179.3
ENSMUST00000092802.5
ENSMUST00000146871.1
Mtmr4


myotubularin related protein 4


chr11_+_62458414 0.674 ENSMUST00000014389.5
Pigl
phosphatidylinositol glycan anchor biosynthesis, class L
chr14_-_31001311 0.671 ENSMUST00000161219.1
ENSMUST00000182501.1
Spcs1

signal peptidase complex subunit 1 homolog (S. cerevisiae)

chr11_-_16508149 0.667 ENSMUST00000109642.1
Sec61g
SEC61, gamma subunit
chr8_+_110847015 0.664 ENSMUST00000172668.1
ENSMUST00000034203.10
ENSMUST00000174398.1
Cog4


component of oligomeric golgi complex 4


chrX_-_100625901 0.661 ENSMUST00000059099.6
Pdzd11
PDZ domain containing 11
chr1_+_33669816 0.658 ENSMUST00000051203.5
1700001G17Rik
RIKEN cDNA 1700001G17 gene
chr13_-_74208661 0.655 ENSMUST00000035934.5
Exoc3
exocyst complex component 3
chr4_+_118620799 0.654 ENSMUST00000030501.8
Ebna1bp2
EBNA1 binding protein 2
chr6_-_124965207 0.653 ENSMUST00000148485.1
Cops7a
COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)
chr5_-_36830647 0.642 ENSMUST00000031002.3
Man2b2
mannosidase 2, alpha B2
chr3_-_65392579 0.633 ENSMUST00000029414.5
Ssr3
signal sequence receptor, gamma
chr15_-_85811644 0.629 ENSMUST00000144067.1
ENSMUST00000134631.1
ENSMUST00000154814.1
ENSMUST00000071876.6
ENSMUST00000150995.1
Cdpf1




cysteine rich, DPF motif domain containing 1




chr2_-_10080055 0.623 ENSMUST00000130067.1
ENSMUST00000139810.1
Atp5c1

ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1

chr11_+_97041554 0.622 ENSMUST00000001485.3
Mrpl10
mitochondrial ribosomal protein L10
chrX_+_107816477 0.610 ENSMUST00000143975.1
ENSMUST00000144695.1
ENSMUST00000167154.1
Fam46d


family with sequence similarity 46, member D


chr7_+_39449479 0.602 ENSMUST00000061201.8
Zfp939
zinc finger protein 939
chr2_+_37443273 0.599 ENSMUST00000133434.1
ENSMUST00000061179.5
Rabgap1

RAB GTPase activating protein 1

chr1_+_91250311 0.581 ENSMUST00000059743.5
ENSMUST00000178627.1
ENSMUST00000171165.1
Ube2f


ubiquitin-conjugating enzyme E2F (putative)



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.8 3.1 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.8 3.1 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.6 1.8 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.6 3.6 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.6 5.4 GO:0071569 protein ufmylation(GO:0071569)
0.6 3.4 GO:0051790 acetate metabolic process(GO:0006083) short-chain fatty acid biosynthetic process(GO:0051790)
0.6 1.7 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.5 1.6 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.5 2.1 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552) oxidative single-stranded RNA demethylation(GO:0035553)
0.5 2.0 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.5 2.5 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.4 3.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.4 1.3 GO:0052572 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.4 2.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.4 1.2 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.4 1.1 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.4 2.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.4 1.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.3 2.0 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.3 0.3 GO:0018307 enzyme active site formation(GO:0018307)
0.3 0.9 GO:0106005 RNA 5'-cap (guanine-N7)-methylation(GO:0106005)
0.3 0.9 GO:1903722 regulation of centriole elongation(GO:1903722)
0.3 1.5 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.3 2.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.3 1.5 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.3 0.8 GO:1905719 protein localization to perinuclear region of cytoplasm(GO:1905719)
0.2 1.2 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.2 0.7 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.2 0.7 GO:0097576 vacuole fusion(GO:0097576)
0.2 0.7 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.2 3.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 3.4 GO:0006465 signal peptide processing(GO:0006465)
0.2 1.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 0.8 GO:1905443 regulation of clathrin coat assembly(GO:1905443) positive regulation of clathrin coat assembly(GO:1905445)
0.2 1.7 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.2 0.9 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.2 3.0 GO:0000338 protein deneddylation(GO:0000338)
0.2 0.5 GO:0019085 early viral transcription(GO:0019085)
0.2 1.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 2.4 GO:0043248 proteasome assembly(GO:0043248)
0.1 2.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 2.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.8 GO:0039019 pronephric nephron development(GO:0039019)
0.1 1.0 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 0.9 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.7 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 1.6 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 1.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.3 GO:0006983 ER overload response(GO:0006983)
0.1 0.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 1.4 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.1 1.0 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 1.3 GO:0070365 hepatocyte differentiation(GO:0070365)
0.1 1.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.9 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.8 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.2 GO:0000239 pachytene(GO:0000239)
0.1 0.6 GO:0006013 mannose metabolic process(GO:0006013)
0.1 2.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.4 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) negative regulation of serotonin secretion(GO:0014063) cellular response to temperature stimulus(GO:0071502)
0.1 0.9 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 4.2 GO:0032543 mitochondrial translation(GO:0032543)
0.1 0.4 GO:0030913 paranodal junction assembly(GO:0030913)
0.1 1.4 GO:0017004 cytochrome complex assembly(GO:0017004)
0.1 1.7 GO:0045116 protein neddylation(GO:0045116)
0.1 1.0 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.1 0.2 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.3 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 1.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 1.0 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 0.1 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.1 2.4 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 0.8 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.4 GO:0030242 autophagy of peroxisome(GO:0030242) peroxisome disassembly(GO:1905683)
0.1 0.5 GO:1901526 positive regulation of mitophagy in response to mitochondrial depolarization(GO:0098779) positive regulation of mitophagy(GO:1901526)
0.1 0.7 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.7 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 3.4 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.5 GO:2000303 regulation of ceramide biosynthetic process(GO:2000303)
0.0 1.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 1.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.7 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0 3.9 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.4 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.8 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.7 GO:0051601 exocyst localization(GO:0051601)
0.0 1.3 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.8 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 1.0 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 1.0 GO:1903513 retrograde protein transport, ER to cytosol(GO:0030970) endoplasmic reticulum to cytosol transport(GO:1903513)
0.0 1.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 1.5 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.7 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 0.6 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.0 0.6 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.9 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.8 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.4 GO:1903543 regulation of exosomal secretion(GO:1903541) positive regulation of exosomal secretion(GO:1903543)
0.0 1.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:1903538 meiotic sister chromatid cohesion, centromeric(GO:0051754) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0 0.7 GO:0071174 mitotic spindle checkpoint(GO:0071174)
0.0 1.5 GO:0045333 cellular respiration(GO:0045333)
0.0 0.7 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 1.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.3 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 1.4 GO:0006986 response to unfolded protein(GO:0006986)
0.0 1.0 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.8 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.7 GO:0015992 proton transport(GO:0015992)
0.0 0.3 GO:0035357 peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.0 0.3 GO:0070266 necroptotic process(GO:0070266)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.4 GO:0099132 ATP hydrolysis coupled cation transmembrane transport(GO:0099132)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.6 3.9 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.5 1.5 GO:0097543 ciliary inversin compartment(GO:0097543)
0.4 3.4 GO:0005787 signal peptidase complex(GO:0005787)
0.4 1.2 GO:0061825 podosome core(GO:0061825)
0.4 2.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.3 2.0 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.3 0.9 GO:0031533 mRNA cap methyltransferase complex(GO:0031533)
0.3 1.4 GO:0071797 LUBAC complex(GO:0071797)
0.3 0.8 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.3 0.8 GO:0044753 amphisome(GO:0044753)
0.2 1.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.2 1.2 GO:0072487 MSL complex(GO:0072487)
0.2 1.7 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 1.3 GO:0000125 PCAF complex(GO:0000125)
0.2 0.8 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.2 0.8 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.2 0.8 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of synaptic membrane(GO:0099243)
0.2 2.5 GO:0036501 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) UFD1-NPL4 complex(GO:0036501)
0.2 0.7 GO:0140007 KICSTOR complex(GO:0140007)
0.2 1.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.2 1.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 3.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 0.9 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 2.1 GO:0017119 Golgi transport complex(GO:0017119)
0.1 4.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 6.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.7 GO:0071819 SAGA complex(GO:0000124) DUBm complex(GO:0071819)
0.1 1.0 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 2.8 GO:0005839 proteasome core complex(GO:0005839)
0.1 1.1 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.8 GO:0097441 basilar dendrite(GO:0097441)
0.1 1.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.2 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.7 GO:0033263 CORVET complex(GO:0033263)
0.1 1.0 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 5.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.9 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.8 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 2.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.2 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 0.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 2.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 1.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0070187 shelterin complex(GO:0070187)
0.0 2.0 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 1.5 GO:0000502 proteasome complex(GO:0000502)
0.0 4.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 2.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.2 GO:0016592 mediator complex(GO:0016592) core mediator complex(GO:0070847)
0.0 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.5 GO:0101031 chaperone complex(GO:0101031)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.6 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 2.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.0 GO:0034657 GID complex(GO:0034657)
0.0 0.0 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 2.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.8 3.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.8 3.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.7 2.1 GO:0051747 cytosine C-5 DNA demethylase activity(GO:0051747)
0.6 1.8 GO:0045159 myosin II binding(GO:0045159)
0.5 1.8 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.4 4.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.4 2.5 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding(GO:0036435)
0.4 2.0 GO:0034235 GPI anchor binding(GO:0034235)
0.3 1.0 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.3 0.9 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity(GO:0004482)
0.3 2.8 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3 1.0 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.2 1.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 1.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.2 0.7 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 5.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 0.9 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 3.1 GO:0022848 acetylcholine-gated cation-selective channel activity(GO:0022848)
0.2 1.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.9 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 3.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 2.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.3 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.1 1.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 1.5 GO:0031386 protein tag(GO:0031386)
0.1 1.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.5 GO:0033188 ceramide phosphoethanolamine synthase activity(GO:0002950) sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 2.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 3.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.8 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 3.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.8 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.4 GO:0001586 Gi/o-coupled serotonin receptor activity(GO:0001586)
0.1 1.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.7 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.3 GO:0061605 thiosulfate sulfurtransferase activity(GO:0004792) molybdopterin-synthase sulfurtransferase activity(GO:0061604) molybdopterin-synthase adenylyltransferase activity(GO:0061605)
0.1 1.1 GO:0046790 virion binding(GO:0046790)
0.1 0.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.9 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 1.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0140035 ubiquitination-like modification-dependent protein binding(GO:0140035) ubiquitin-dependent protein binding(GO:0140036)
0.0 0.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.6 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.9 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.9 GO:0031210 phosphatidylcholine binding(GO:0031210) quaternary ammonium group binding(GO:0050997)
0.0 1.3 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 6.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.6 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.8 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding(GO:0070530)
0.0 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 1.7 GO:0001540 amyloid-beta binding(GO:0001540)
0.0 1.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 2.2 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 1.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 6.1 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 1.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.4 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.8 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 1.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 1.2 GO:0140034 methylated histone binding(GO:0035064) methylation-dependent protein binding(GO:0140034)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.3 GO:0005518 collagen binding(GO:0005518)
0.0 1.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.8 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 1.2 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 3.9 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 3.3 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 3.0 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.9 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.6 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.8 PID_ARF_3PATHWAY Arf1 pathway
0.0 1.4 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 4.2 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 1.1 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.7 PID_INSULIN_PATHWAY Insulin Pathway
0.0 0.4 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.2 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.8 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 1.3 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.1 WNT_SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.4 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.2 3.1 REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.2 3.4 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 3.4 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.9 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.1 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.5 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 8.0 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 6.4 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway
0.1 1.7 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 2.9 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.1 1.5 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.1 0.8 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 2.7 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 4.7 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.1 1.9 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.3 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 3.1 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.0 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 0.8 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 0.9 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.4 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.9 REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.1 1.2 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 0.7 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.2 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.6 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.9 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.9 REACTOME_SIGNALING_BY_SCF_KIT Genes involved in Signaling by SCF-KIT
0.0 0.6 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.4 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse