Motif ID: Fli1

Z-value: 1.343


Transcription factors associated with Fli1:

Gene SymbolEntrez IDGene Name
Fli1 ENSMUSG00000016087.7 Fli1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fli1mm10_v2_chr9_-_32542861_32543008-0.701.6e-06Click!


Activity profile for motif Fli1.

activity profile for motif Fli1


Sorted Z-values histogram for motif Fli1

Sorted Z-values for motif Fli1



Network of associatons between targets according to the STRING database.



First level regulatory network of Fli1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_40187277 30.065 ENSMUST00000051846.6
Cyp2c70
cytochrome P450, family 2, subfamily c, polypeptide 70
chr8_-_24576297 24.441 ENSMUST00000033953.7
ENSMUST00000121992.1
Ido2

indoleamine 2,3-dioxygenase 2

chr10_+_128971191 22.488 ENSMUST00000181142.1
9030616G12Rik
RIKEN cDNA 9030616G12 gene
chr1_-_175491130 17.154 ENSMUST00000027812.5
Rgs7
regulator of G protein signaling 7
chr9_-_57683644 16.496 ENSMUST00000034860.3
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
chrX_-_136868537 13.701 ENSMUST00000058814.6
Rab9b
RAB9B, member RAS oncogene family
chr7_-_26939377 12.236 ENSMUST00000170227.1
Cyp2a22
cytochrome P450, family 2, subfamily a, polypeptide 22
chr17_-_32424139 11.336 ENSMUST00000114455.1
Pglyrp2
peptidoglycan recognition protein 2
chr19_+_46131888 7.229 ENSMUST00000043739.3
Elovl3
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3
chr13_-_4523322 6.123 ENSMUST00000080361.5
ENSMUST00000078239.3
Akr1c20

aldo-keto reductase family 1, member C20

chr3_-_122924103 6.076 ENSMUST00000180557.1
4933405D12Rik
RIKEN cDNA 4933405D12 gene
chr17_+_28858411 5.770 ENSMUST00000114737.1
ENSMUST00000056866.5
Pnpla1

patatin-like phospholipase domain containing 1

chr9_-_109568262 5.595 ENSMUST00000056745.6
Fbxw15
F-box and WD-40 domain protein 15
chr7_-_13837410 5.497 ENSMUST00000108522.3
Sult2a1
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr9_+_111439063 5.420 ENSMUST00000111879.3
Dclk3
doublecortin-like kinase 3
chr14_+_52855614 5.272 ENSMUST00000181038.1
Trav14d-1
T cell receptor alpha variable 14D-1
chr11_-_5915124 5.267 ENSMUST00000109823.2
ENSMUST00000109822.1
Gck

glucokinase

chr15_-_97020322 5.229 ENSMUST00000166223.1
Slc38a4
solute carrier family 38, member 4
chr15_-_76126538 4.710 ENSMUST00000054022.5
ENSMUST00000089654.3
BC024139

cDNA sequence BC024139

chr10_+_84756055 4.709 ENSMUST00000060397.6
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr17_+_79051906 4.557 ENSMUST00000040789.4
Qpct
glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
chr5_-_73338580 4.333 ENSMUST00000087195.5
Ociad2
OCIA domain containing 2
chr9_+_40187079 4.325 ENSMUST00000062229.5
Olfr986
olfactory receptor 986
chr9_+_78230644 4.131 ENSMUST00000098537.3
Gsta1
glutathione S-transferase, alpha 1 (Ya)
chr11_+_16752203 4.105 ENSMUST00000102884.3
ENSMUST00000020329.6
Egfr

epidermal growth factor receptor

chr1_-_155527083 4.090 ENSMUST00000097531.2
Gm5532
predicted gene 5532
chr2_+_58754910 4.048 ENSMUST00000059102.6
Upp2
uridine phosphorylase 2
chr6_-_146634588 3.920 ENSMUST00000037709.9
Tm7sf3
transmembrane 7 superfamily member 3
chr10_-_85957775 3.901 ENSMUST00000001834.3
Rtcb
RNA 2',3'-cyclic phosphate and 5'-OH ligase
chr13_-_51203065 3.832 ENSMUST00000091708.4
Hist1h2al
histone cluster 1, H2al
chr6_-_117214048 3.561 ENSMUST00000170447.1
Rpl28-ps4
ribosomal protein L28, pseudogene 4
chr13_+_4434306 3.456 ENSMUST00000021630.8
Akr1c6
aldo-keto reductase family 1, member C6
chrX_-_72656135 3.040 ENSMUST00000055966.6
Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr4_+_43406435 2.971 ENSMUST00000098106.2
ENSMUST00000139198.1
Rusc2

RUN and SH3 domain containing 2

chr6_+_138140298 2.584 ENSMUST00000008684.4
Mgst1
microsomal glutathione S-transferase 1
chr17_-_31144271 2.480 ENSMUST00000024826.7
Tff2
trefoil factor 2 (spasmolytic protein 1)
chr6_+_138140521 2.461 ENSMUST00000120939.1
ENSMUST00000120302.1
Mgst1

microsomal glutathione S-transferase 1

chr8_-_71486037 2.455 ENSMUST00000093450.4
Ano8
anoctamin 8
chr6_+_124493101 2.417 ENSMUST00000049124.9
C1rl
complement component 1, r subcomponent-like
chr18_-_20059478 2.406 ENSMUST00000075214.2
ENSMUST00000039247.4
Dsc2

desmocollin 2

chr16_+_37580137 2.356 ENSMUST00000160847.1
Hgd
homogentisate 1, 2-dioxygenase
chr10_+_19934472 2.319 ENSMUST00000095806.3
ENSMUST00000120259.1
Map3k5

mitogen-activated protein kinase kinase kinase 5

chr10_+_26229707 2.234 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr7_+_13733502 2.124 ENSMUST00000086148.6
Sult2a2
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2
chrX_+_140381971 2.078 ENSMUST00000044702.6
Frmpd3
FERM and PDZ domain containing 3
chr7_-_80405425 2.055 ENSMUST00000107362.3
ENSMUST00000135306.1
Furin

furin (paired basic amino acid cleaving enzyme)

chr8_-_3720640 2.022 ENSMUST00000062037.6
Clec4g
C-type lectin domain family 4, member g
chr9_+_50575273 1.998 ENSMUST00000059081.6
ENSMUST00000180021.1
Il18

interleukin 18

chr18_-_75697639 1.992 ENSMUST00000165559.1
Ctif
CBP80/20-dependent translation initiation factor
chr17_-_45595842 1.970 ENSMUST00000164618.1
ENSMUST00000097317.3
ENSMUST00000170113.1
Slc29a1


solute carrier family 29 (nucleoside transporters), member 1


chr11_-_100759740 1.940 ENSMUST00000107361.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr10_-_127621107 1.907 ENSMUST00000049149.8
Lrp1
low density lipoprotein receptor-related protein 1
chr19_+_37685581 1.851 ENSMUST00000073391.4
Cyp26c1
cytochrome P450, family 26, subfamily c, polypeptide 1
chr6_-_119417479 1.837 ENSMUST00000032272.6
Adipor2
adiponectin receptor 2
chr9_+_118478344 1.777 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr7_-_19822698 1.733 ENSMUST00000120537.1
Bcl3
B cell leukemia/lymphoma 3
chr9_+_118478182 1.704 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr9_+_118478851 1.687 ENSMUST00000150633.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr7_-_16244152 1.631 ENSMUST00000171425.1
C5ar2
complement component 5a receptor 2
chr14_+_53640701 1.572 ENSMUST00000179267.2
Trav14-2
T cell receptor alpha variable 14-2
chr4_+_40722912 1.568 ENSMUST00000164233.1
ENSMUST00000137246.1
ENSMUST00000125442.1
Dnaja1


DnaJ (Hsp40) homolog, subfamily A, member 1


chr2_-_6951680 1.566 ENSMUST00000076071.2
Gm10115
predicted gene 10115
chr12_+_87514315 1.553 ENSMUST00000110152.2
Gm8300
predicted gene 8300
chr10_-_127620960 1.524 ENSMUST00000121829.1
Lrp1
low density lipoprotein receptor-related protein 1
chr4_+_33078796 1.460 ENSMUST00000131920.1
Gabrr2
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
chr5_+_43672289 1.426 ENSMUST00000156034.1
Cc2d2a
coiled-coil and C2 domain containing 2A
chr10_-_127620922 1.423 ENSMUST00000118455.1
Lrp1
low density lipoprotein receptor-related protein 1
chr14_-_46390576 1.409 ENSMUST00000074077.5
Bmp4
bone morphogenetic protein 4
chr5_-_151233818 1.368 ENSMUST00000126770.1
Stard13
StAR-related lipid transfer (START) domain containing 13
chr9_+_44107268 1.360 ENSMUST00000114821.2
ENSMUST00000114818.2
C1qtnf5

C1q and tumor necrosis factor related protein 5

chr9_+_44107286 1.355 ENSMUST00000152956.1
ENSMUST00000114815.1
C1qtnf5

C1q and tumor necrosis factor related protein 5

chr9_+_44107226 1.328 ENSMUST00000114816.1
C1qtnf5
C1q and tumor necrosis factor related protein 5
chr4_+_42158092 1.309 ENSMUST00000098122.2
Gm13306
predicted gene 13306
chr4_+_148602527 1.302 ENSMUST00000105701.2
ENSMUST00000052060.6
Masp2

mannan-binding lectin serine peptidase 2

chr9_-_65021645 1.295 ENSMUST00000036615.5
Ptplad1
protein tyrosine phosphatase-like A domain containing 1
chr14_-_46390501 1.281 ENSMUST00000100676.2
Bmp4
bone morphogenetic protein 4
chr5_+_127632238 1.237 ENSMUST00000118139.1
Glt1d1
glycosyltransferase 1 domain containing 1
chr1_+_182763961 1.225 ENSMUST00000153348.1
Susd4
sushi domain containing 4
chr6_-_57692007 1.220 ENSMUST00000053386.5
ENSMUST00000185014.1
Pyurf
PYURF
Pigy upstream reading frame
protein preY, mitochondrial precursor
chr4_+_42655251 1.160 ENSMUST00000177785.1
Ccl27b
chemokine (C-C motif) ligand 27b
chr6_-_77979515 1.152 ENSMUST00000159626.1
ENSMUST00000075340.5
ENSMUST00000162273.1
Ctnna2


catenin (cadherin associated protein), alpha 2


chr17_+_6106880 1.138 ENSMUST00000149756.1
Tulp4
tubby like protein 4
chr5_+_119834663 1.080 ENSMUST00000018407.6
Tbx5
T-box 5
chr4_+_104328252 1.078 ENSMUST00000094945.1
Gm10304
predicted gene 10304
chr17_-_24644933 1.063 ENSMUST00000019684.5
Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr5_-_66173051 1.039 ENSMUST00000113726.1
Rbm47
RNA binding motif protein 47
chr8_-_45410539 1.025 ENSMUST00000034056.4
ENSMUST00000167106.1
Tlr3

toll-like receptor 3

chr3_+_144570409 1.014 ENSMUST00000082437.3
Sep15
selenoprotein
chr8_+_88174560 1.002 ENSMUST00000074808.2
9430002A10Rik
RIKEN cDNA 9430002A10 gene
chr2_+_79635416 1.002 ENSMUST00000111788.1
Ssfa2
sperm specific antigen 2
chrX_-_155128409 0.981 ENSMUST00000076671.3
1700042B14Rik
RIKEN cDNA 1700042B14 gene
chr9_+_45055166 0.980 ENSMUST00000114664.1
ENSMUST00000093856.3
Mpzl3

myelin protein zero-like 3

chr7_+_35186370 0.937 ENSMUST00000135452.1
ENSMUST00000001854.5
Slc7a10

solute carrier family 7 (cationic amino acid transporter, y+ system), member 10

chrX_-_37168829 0.925 ENSMUST00000046557.5
Akap14
A kinase (PRKA) anchor protein 14
chr4_+_40723084 0.916 ENSMUST00000149794.1
Dnaja1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr2_+_79635444 0.906 ENSMUST00000111784.2
Ssfa2
sperm specific antigen 2
chr7_-_104777470 0.902 ENSMUST00000053464.8
Usp17le
ubiquitin specific peptidase 17-like E
chr2_-_119547627 0.888 ENSMUST00000060009.2
Exd1
exonuclease 3'-5' domain containing 1
chr9_+_45055211 0.879 ENSMUST00000114663.2
Mpzl3
myelin protein zero-like 3
chr13_+_42709482 0.877 ENSMUST00000066928.5
ENSMUST00000148891.1
Phactr1

phosphatase and actin regulator 1

chr11_+_17257558 0.855 ENSMUST00000000594.2
ENSMUST00000156784.1
C1d

C1D nuclear receptor co-repressor

chr5_-_151233768 0.849 ENSMUST00000129088.1
Stard13
StAR-related lipid transfer (START) domain containing 13
chr2_+_119547697 0.831 ENSMUST00000014221.6
ENSMUST00000119172.1
Chp1

calcineurin-like EF hand protein 1

chr10_+_21993890 0.830 ENSMUST00000092673.4
Sgk1
serum/glucocorticoid regulated kinase 1
chr1_-_191318090 0.813 ENSMUST00000046770.9
Nenf
neuron derived neurotrophic factor
chr12_+_100199435 0.809 ENSMUST00000110082.3
Calm1
calmodulin 1
chr5_-_120711927 0.804 ENSMUST00000031607.6
Dtx1
deltex 1 homolog (Drosophila)
chr11_+_96251100 0.793 ENSMUST00000129907.2
Gm53
predicted gene 53
chr2_+_79635352 0.790 ENSMUST00000111785.2
Ssfa2
sperm specific antigen 2
chr16_-_11066141 0.783 ENSMUST00000162323.1
Litaf
LPS-induced TN factor
chr3_-_106406090 0.758 ENSMUST00000029510.7
BC051070
cDNA sequence BC051070
chr5_+_92137896 0.744 ENSMUST00000031355.6
Uso1
USO1 vesicle docking factor
chr5_+_123252087 0.741 ENSMUST00000121964.1
Wdr66
WD repeat domain 66
chr2_-_38287347 0.741 ENSMUST00000102787.3
Dennd1a
DENN/MADD domain containing 1A
chr4_-_150001231 0.728 ENSMUST00000153394.1
H6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr4_-_149454971 0.719 ENSMUST00000030848.2
Rbp7
retinol binding protein 7, cellular
chr9_-_8004585 0.691 ENSMUST00000086580.5
ENSMUST00000065353.6
Yap1

yes-associated protein 1

chr2_+_65845833 0.687 ENSMUST00000053910.3
Csrnp3
cysteine-serine-rich nuclear protein 3
chr10_-_71285234 0.684 ENSMUST00000020085.6
Ube2d1
ubiquitin-conjugating enzyme E2D 1
chr7_+_3390629 0.651 ENSMUST00000182222.1
Cacng8
calcium channel, voltage-dependent, gamma subunit 8
chr9_-_124311750 0.645 ENSMUST00000177714.1
2010315B03Rik
RIKEN cDNA 2010315B03 gene
chr4_-_41697040 0.644 ENSMUST00000102962.3
ENSMUST00000084701.5
Cntfr

ciliary neurotrophic factor receptor

chr6_-_88446491 0.640 ENSMUST00000165242.1
Eefsec
eukaryotic elongation factor, selenocysteine-tRNA-specific
chr6_+_91914759 0.619 ENSMUST00000059318.7
4930590J08Rik
RIKEN cDNA 4930590J08 gene
chr9_+_74848437 0.611 ENSMUST00000161862.1
ENSMUST00000162089.1
ENSMUST00000160017.1
ENSMUST00000160950.1
Gm16551


Gm20649
predicted gene 16551


predicted gene 20649
chr19_-_8880883 0.597 ENSMUST00000096253.5
AI462493
expressed sequence AI462493
chrX_+_42068398 0.581 ENSMUST00000115095.2
Xiap
X-linked inhibitor of apoptosis
chr4_+_147940859 0.578 ENSMUST00000103232.1
2510039O18Rik
RIKEN cDNA 2510039O18 gene
chr11_-_97187872 0.562 ENSMUST00000001479.4
Kpnb1
karyopherin (importin) beta 1
chr3_-_144570136 0.549 ENSMUST00000043325.7
Hs2st1
heparan sulfate 2-O-sulfotransferase 1
chr4_-_25800239 0.548 ENSMUST00000108199.1
Fut9
fucosyltransferase 9
chr10_+_84917616 0.526 ENSMUST00000038523.7
ENSMUST00000095385.3
Ric8b

resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)

chr11_+_57011945 0.518 ENSMUST00000094179.4
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chrX_+_31336454 0.515 ENSMUST00000180197.1
Gm2784
predicted gene 2784
chr7_-_4996095 0.515 ENSMUST00000108572.1
Zfp579
zinc finger protein 579
chr1_-_180330550 0.476 ENSMUST00000050581.3
Gm5069
predicted pseudogene 5069
chr10_+_102512216 0.470 ENSMUST00000055355.4
Rassf9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr9_+_104569754 0.469 ENSMUST00000077190.6
Cpne4
copine IV
chr3_+_89136572 0.469 ENSMUST00000107482.3
ENSMUST00000127058.1
Pklr

pyruvate kinase liver and red blood cell

chr18_-_56975333 0.467 ENSMUST00000139243.2
ENSMUST00000025488.8
C330018D20Rik

RIKEN cDNA C330018D20 gene

chr9_+_104569671 0.463 ENSMUST00000057742.8
Cpne4
copine IV
chr19_+_8735808 0.461 ENSMUST00000049424.9
Wdr74
WD repeat domain 74
chrX_+_33657172 0.458 ENSMUST00000177912.1
Gm2927
predicted gene 2927
chr5_-_135349991 0.447 ENSMUST00000044972.7
Fkbp6
FK506 binding protein 6
chr10_+_24595434 0.438 ENSMUST00000020171.5
Ctgf
connective tissue growth factor
chr16_+_48283735 0.435 ENSMUST00000096045.1
ENSMUST00000050705.2
Dppa4

developmental pluripotency associated 4

chr11_-_79296906 0.433 ENSMUST00000068448.2
Gm9964
predicted gene 9964
chr9_-_89177813 0.433 ENSMUST00000098484.3
4930579C12Rik
RIKEN cDNA 4930579C12 gene
chr15_-_98763195 0.432 ENSMUST00000053183.9
Arf3
ADP-ribosylation factor 3
chr13_-_46191048 0.426 ENSMUST00000072437.3
Gm10113
predicted gene 10113
chrX_-_34161499 0.424 ENSMUST00000178219.1
Gm21681
predicted gene, 21681
chr2_-_84650760 0.423 ENSMUST00000111691.1
Ctnnd1
catenin (cadherin associated protein), delta 1
chr3_-_90490975 0.422 ENSMUST00000149884.1
Snapin
SNAP-associated protein
chr2_-_84650676 0.419 ENSMUST00000067232.3
Ctnnd1
catenin (cadherin associated protein), delta 1
chrX_+_32894625 0.415 ENSMUST00000179069.1
Gm21657
predicted gene, 21657
chr11_-_95076797 0.405 ENSMUST00000145671.1
ENSMUST00000120375.1
Itga3

integrin alpha 3

chrX_+_31117674 0.401 ENSMUST00000179532.1
Gm21447
predicted gene, 21447
chr14_+_54883377 0.399 ENSMUST00000022806.3
ENSMUST00000172844.1
ENSMUST00000133397.2
ENSMUST00000134077.1
Bcl2l2


Gm20521
BCL2-like 2


predicted gene 20521
chrX_-_33702349 0.398 ENSMUST00000105117.2
Gm2933
predicted gene 2933
chrX_+_32047829 0.397 ENSMUST00000178747.1
Gm21645
predicted gene, 21645
chrX_-_33956540 0.391 ENSMUST00000179466.1
Gm2964
predicted gene 2964
chrX_+_109095359 0.382 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr2_+_158502633 0.378 ENSMUST00000109484.1
Adig
adipogenin
chr7_+_103415072 0.374 ENSMUST00000106892.1
Usp17lc
ubiquitin specific peptidase 17-like C
chr11_+_57011798 0.365 ENSMUST00000036315.9
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr11_-_95076657 0.359 ENSMUST00000001548.7
Itga3
integrin alpha 3
chr10_+_24595623 0.354 ENSMUST00000176228.1
ENSMUST00000129142.1
Ctgf

connective tissue growth factor

chr4_-_41731142 0.348 ENSMUST00000171251.1
ENSMUST00000159930.1
Arid3c

AT rich interactive domain 3C (BRIGHT-like)

chr3_+_156561950 0.348 ENSMUST00000041425.5
ENSMUST00000106065.1
Negr1

neuronal growth regulator 1

chr11_+_87595646 0.344 ENSMUST00000134216.1
Mtmr4
myotubularin related protein 4
chr5_-_134456227 0.343 ENSMUST00000111244.1
Gtf2ird1
general transcription factor II I repeat domain-containing 1
chrX_-_19481319 0.334 ENSMUST00000089246.5
BC049702
cDNA sequence BC049702
chr15_-_98762992 0.329 ENSMUST00000156572.1
Arf3
ADP-ribosylation factor 3
chr9_-_109195520 0.326 ENSMUST00000173549.1
Fbxw13
F-box and WD-40 domain protein 13
chr1_+_42952872 0.318 ENSMUST00000179766.1
Gpr45
G protein-coupled receptor 45
chrX_+_32726137 0.317 ENSMUST00000179585.1
Gm21951
predicted gene, 21951
chr14_-_56234650 0.315 ENSMUST00000015585.2
Gzmc
granzyme C
chr2_-_84650714 0.314 ENSMUST00000111697.2
ENSMUST00000111670.2
ENSMUST00000111696.1
ENSMUST00000111678.1
ENSMUST00000111690.1
ENSMUST00000111695.1
ENSMUST00000111677.1
ENSMUST00000111698.1
ENSMUST00000099941.2
ENSMUST00000111676.1
ENSMUST00000111694.1
ENSMUST00000111675.1
ENSMUST00000111689.1
ENSMUST00000111687.1
ENSMUST00000111692.1
ENSMUST00000111685.1
ENSMUST00000111686.1
ENSMUST00000111688.1
ENSMUST00000111693.1
ENSMUST00000111684.1
Ctnnd1



















catenin (cadherin associated protein), delta 1



















chrX_-_3443690 0.310 ENSMUST00000105020.1
Gm14346
predicted gene 14346
chr2_+_158502612 0.300 ENSMUST00000059889.3
Adig
adipogenin
chrX_-_33577346 0.281 ENSMUST00000105119.3
Gm2913
predicted gene 2913
chrX_+_3700233 0.281 ENSMUST00000105019.2
Gm14345
predicted gene 14345
chrX_+_32560055 0.281 ENSMUST00000178070.1
Gmcl1l
germ cell-less homolog 1 (Drosophila)-like
chrX_-_3752885 0.281 ENSMUST00000178621.1
Gm14351
predicted gene 14351
chrX_+_32278394 0.281 ENSMUST00000179991.1
Gm2799
predicted gene 2799
chr9_-_109495875 0.279 ENSMUST00000076617.4
Fbxw19
F-box and WD-40 domain protein 19
chr7_+_104857009 0.276 ENSMUST00000067695.7
Usp17la
ubiquitin specific peptidase 17-like A
chrX_-_31383918 0.274 ENSMUST00000178444.1
Gm2777
predicted gene 2777
chr14_-_20664562 0.269 ENSMUST00000119483.1
Synpo2l
synaptopodin 2-like
chr1_+_42953106 0.266 ENSMUST00000179655.1
Gpr45
G protein-coupled receptor 45
chr14_-_52305056 0.265 ENSMUST00000174853.1
ENSMUST00000022767.9
Mettl3

methyltransferase like 3

chrX_+_4370636 0.264 ENSMUST00000105014.1
Gm10922
predicted gene 10922
chrX_-_3957002 0.264 ENSMUST00000105017.3
Gm3701
predicted gene 3701
chrX_+_33313338 0.264 ENSMUST00000180039.1
Gm2863
predicted gene 2863
chrX_+_32973897 0.264 ENSMUST00000179538.1
Gm2825
predicted gene 2825
chr14_+_105498788 0.263 ENSMUST00000022711.1
4930449E01Rik
RIKEN cDNA 4930449E01 gene
chr7_-_4603105 0.262 ENSMUST00000049113.7
Ptprh
protein tyrosine phosphatase, receptor type, H
chr17_+_13228852 0.255 ENSMUST00000162940.1
Smok2b
sperm motility kinase 2B
chrX_+_4196576 0.252 ENSMUST00000105015.2
Gm14347
predicted gene 14347
chrX_-_4291245 0.247 ENSMUST00000179325.1
Gm10921
predicted gene 10921

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.5 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
2.3 11.3 GO:0032824 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
2.2 24.4 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
1.5 4.6 GO:0018199 peptidyl-glutamine modification(GO:0018199)
1.3 5.2 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
1.3 42.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
1.3 5.0 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
1.2 4.9 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
1.2 3.5 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
1.1 5.3 GO:0034287 detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.9 4.7 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.9 2.7 GO:0048389 intermediate mesoderm development(GO:0048389) cloacal septation(GO:0060197) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) cardiac jelly development(GO:1905072) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137)
0.9 1.7 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.7 4.1 GO:1900020 prolactin secretion(GO:0070459) regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.7 2.0 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.6 7.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.6 2.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.5 2.1 GO:0090472 dibasic protein processing(GO:0090472)
0.5 2.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.5 1.9 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.4 2.5 GO:1905258 regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway(GO:1905258) negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway(GO:1905259)
0.4 1.2 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
0.4 1.6 GO:0090024 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024)
0.4 1.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.4 2.5 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.3 2.0 GO:0015862 uridine transport(GO:0015862)
0.3 3.9 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.3 5.5 GO:0051923 sulfation(GO:0051923)
0.2 2.4 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.2 1.2 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.2 1.8 GO:0061042 vascular wound healing(GO:0061042)
0.2 0.8 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.2 1.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.2 1.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.2 0.7 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.2 0.6 GO:0003360 brainstem development(GO:0003360)
0.2 4.1 GO:0035634 response to stilbenoid(GO:0035634)
0.2 0.8 GO:0070318 extracellular matrix constituent secretion(GO:0070278) positive regulation of G0 to G1 transition(GO:0070318)
0.2 13.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 0.6 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.1 0.5 GO:0030202 heparin metabolic process(GO:0030202)
0.1 2.3 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
0.1 1.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 4.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.9 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 17.2 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 0.6 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.4 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 0.9 GO:0042940 D-amino acid transport(GO:0042940)
0.1 1.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 2.0 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 2.5 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 2.9 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.8 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 0.2 GO:0070268 cornification(GO:0070268)
0.1 0.6 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.7 GO:0060242 contact inhibition(GO:0060242)
0.1 0.2 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.1 0.2 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.1 0.4 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 1.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.3 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.7 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.1 2.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 6.2 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.1 0.5 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.8 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.8 GO:0032099 negative regulation of appetite(GO:0032099)
0.1 1.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 0.3 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 5.2 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 2.9 GO:0070206 protein trimerization(GO:0070206)
0.0 0.7 GO:0006098 pentose-phosphate shunt(GO:0006098) pentose-phosphate shunt, oxidative branch(GO:0009051) pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.4 GO:0007631 feeding behavior(GO:0007631)
0.0 0.4 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.3 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 6.1 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 1.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 4.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.9 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.4 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.8 GO:0045581 negative regulation of T cell differentiation(GO:0045581)
0.0 0.4 GO:0036065 fucosylation(GO:0036065)
0.0 0.7 GO:2000311 regulation of AMPA receptor activity(GO:2000311)
0.0 0.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 2.1 GO:0008202 steroid metabolic process(GO:0008202)
0.0 0.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.8 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.3 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.7 17.2 GO:0044292 dendrite terminus(GO:0044292)
0.6 1.7 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.5 4.0 GO:0045098 type III intermediate filament(GO:0045098)
0.4 3.9 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.3 2.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.3 5.3 GO:0045180 basal cortex(GO:0045180)
0.3 0.8 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.2 0.7 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 4.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 0.8 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.2 13.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.2 0.9 GO:1990923 PET complex(GO:1990923)
0.1 2.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.9 GO:0044308 axonal spine(GO:0044308)
0.1 0.9 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.1 1.2 GO:0005915 zonula adherens(GO:0005915)
0.1 1.4 GO:0036038 MKS complex(GO:0036038)
0.1 8.2 GO:0005811 lipid droplet(GO:0005811)
0.1 1.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 2.4 GO:0030057 desmosome(GO:0030057)
0.1 5.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.4 GO:0099078 BORC complex(GO:0099078)
0.1 0.3 GO:0036396 MIS complex(GO:0036396)
0.1 0.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 7.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.9 GO:0000178 exosome (RNase complex)(GO:0000178) exoribonuclease complex(GO:1905354)
0.0 4.0 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 2.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.9 GO:0097440 apical dendrite(GO:0097440)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 4.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
8.1 24.4 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
2.7 16.5 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
2.3 11.3 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
1.6 4.9 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
1.4 42.3 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
1.2 3.5 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.8 18.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.8 4.0 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.8 5.5 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.6 1.9 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.6 7.2 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.5 1.8 GO:0097003 adipokinetic hormone receptor activity(GO:0097003) adipokinetic hormone binding(GO:0097004)
0.4 1.6 GO:0001847 opsonin receptor activity(GO:0001847)
0.4 1.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.3 4.1 GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity(GO:0004716)
0.3 9.2 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.3 2.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.3 3.9 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.3 2.7 GO:0039706 co-receptor binding(GO:0039706)
0.3 6.1 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.3 5.3 GO:0005536 glucose binding(GO:0005536)
0.2 0.7 GO:0047936 glucose dehydrogenase activity(GO:0004344) glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.2 0.8 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.2 2.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 4.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 2.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.9 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897) ciliary neurotrophic factor binding(GO:0070119)
0.1 3.7 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 0.8 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 2.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229) intracellular chloride channel activity(GO:0061778)
0.1 2.0 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 2.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.5 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.6 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 2.9 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 1.3 GO:0001846 opsonin binding(GO:0001846)
0.1 2.0 GO:0030247 polysaccharide binding(GO:0030247)
0.1 0.9 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) L-serine transporter activity(GO:1905361)
0.1 0.3 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.7 GO:0016918 retinal binding(GO:0016918)
0.1 5.2 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.8 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 2.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 2.7 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 14.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 4.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.9 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.8 GO:0043236 laminin binding(GO:0043236)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0051400 BH domain binding(GO:0051400)
0.0 0.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.9 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 2.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.9 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 2.3 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 7.6 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.1 2.0 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.1 5.6 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 0.8 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 4.8 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 3.4 PID_BMP_PATHWAY BMP receptor signaling
0.1 1.7 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.1 5.5 PID_E2F_PATHWAY E2F transcription factor network
0.1 0.8 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.2 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 2.5 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.2 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 2.1 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 1.0 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 6.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.8 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.0 0.9 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 0.8 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.7 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.7 PID_P53_REGULATION_PATHWAY p53 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.5 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
1.4 24.4 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.4 5.5 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 7.2 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 4.0 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.2 9.0 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.2 3.0 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.2 1.3 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 3.7 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.2 5.7 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.1 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 6.2 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.5 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 1.0 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.9 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 17.2 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.1 2.6 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.8 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 2.0 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.7 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.0 0.9 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.8 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 1.2 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.7 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 2.0 REACTOME_SIGNALING_BY_ILS Genes involved in Signaling by Interleukins
0.0 0.5 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.0 2.2 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.4 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives