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GSE58827: Dynamics of the Mouse Liver

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Results for Fosb

Z-value: 0.42

Motif logo

Transcription factors associated with Fosb

Gene Symbol Gene ID Gene Info
ENSMUSG00000003545.2 FBJ osteosarcoma oncogene B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Fosbmm10_v2_chr7_-_19310035_19310050-0.353.5e-02Click!

Activity profile of Fosb motif

Sorted Z-values of Fosb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_7445822 1.34 ENSMUST00000034497.6
matrix metallopeptidase 3
chr5_-_24392012 0.82 ENSMUST00000059401.6
autophagy related 9B
chr1_+_165769392 0.61 ENSMUST00000040298.4
cellular repressor of E1A-stimulated genes 1
chr17_-_45592485 0.52 ENSMUST00000166119.1
solute carrier family 29 (nucleoside transporters), member 1
chr7_+_126776939 0.49 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
yippee-like 3 (Drosophila)
chr17_-_45592262 0.48 ENSMUST00000164769.1
solute carrier family 29 (nucleoside transporters), member 1
chr19_+_5877794 0.48 ENSMUST00000145200.1
ENSMUST00000025732.7
ENSMUST00000125114.1
ENSMUST00000155697.1
solute carrier family 25, member 45
chr10_+_88091070 0.46 ENSMUST00000048621.7
pro-melanin-concentrating hormone
chr9_+_108953578 0.45 ENSMUST00000112070.1
collagen, type VII, alpha 1
chr9_+_108953597 0.45 ENSMUST00000026740.5
collagen, type VII, alpha 1
chr11_-_100248902 0.44 ENSMUST00000007280.8
keratin 16
chr7_+_30787897 0.42 ENSMUST00000098559.1
keratinocyte differentiation associated protein
chr11_-_120630516 0.41 ENSMUST00000106181.1
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr1_-_74893109 0.40 ENSMUST00000006721.2
crystallin, beta A2
chrX_-_75578188 0.39 ENSMUST00000033545.5
RAB39B, member RAS oncogene family
chr18_+_44071390 0.39 ENSMUST00000068473.2
serine peptidase inhibitor, Kazal type 6
chr8_-_110039330 0.38 ENSMUST00000109222.2
carbohydrate (chondroitin 6/keratan) sulfotransferase 4
chr7_-_4778141 0.38 ENSMUST00000094892.5
interleukin 11
chr11_-_84067063 0.37 ENSMUST00000108101.1
dual specificity phosphatase 14
chr10_+_24447468 0.36 ENSMUST00000134627.1
predicted gene 15271
chr7_-_133782721 0.34 ENSMUST00000063669.1
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr3_-_88503331 0.34 ENSMUST00000029699.6
lamin A
chr3_-_88503187 0.34 ENSMUST00000120377.1
lamin A
chr1_-_51915968 0.33 ENSMUST00000046390.7
myosin IB
chr12_-_85288419 0.33 ENSMUST00000121930.1
acylphosphatase 1, erythrocyte (common) type
chr11_-_69549108 0.33 ENSMUST00000108659.1
dynein, axonemal, heavy chain 2
chr7_+_141079125 0.33 ENSMUST00000159375.1
plakophilin 3
chr4_+_42158092 0.33 ENSMUST00000098122.2
predicted gene 13306
chr5_+_31116702 0.33 ENSMUST00000013771.8
tripartite motif-containing 54
chr17_-_30612613 0.31 ENSMUST00000167624.1
ENSMUST00000024823.6
glyoxalase 1
chr9_+_44240668 0.29 ENSMUST00000092426.3
coiled-coil domain containing 153
chr11_+_80428598 0.28 ENSMUST00000173938.1
ENSMUST00000017572.7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr7_-_80401707 0.28 ENSMUST00000120753.1
furin (paired basic amino acid cleaving enzyme)
chr19_-_4139605 0.28 ENSMUST00000025761.6
calcium binding protein 4
chr5_+_31116722 0.27 ENSMUST00000114637.1
tripartite motif-containing 54
chr13_-_54611274 0.26 ENSMUST00000049575.7
clathrin, light polypeptide (Lcb)
chr10_-_86011833 0.25 ENSMUST00000105304.1
ENSMUST00000061699.5
BPI fold containing family C
chr10_+_26078255 0.25 ENSMUST00000041011.3
predicted gene 9767
chr14_+_66635251 0.24 ENSMUST00000159365.1
ENSMUST00000054661.1
ENSMUST00000159068.1
adrenergic receptor, alpha 1a
chr13_-_54611332 0.23 ENSMUST00000091609.4
clathrin, light polypeptide (Lcb)
chr2_+_143915273 0.23 ENSMUST00000103172.3
destrin
chr2_-_151632471 0.23 ENSMUST00000137936.1
ENSMUST00000146172.1
ENSMUST00000094456.3
ENSMUST00000148755.1
ENSMUST00000109875.1
ENSMUST00000028951.7
ENSMUST00000109877.3
syntaphilin
chr7_+_139834148 0.23 ENSMUST00000026548.7
G protein-coupled receptor 123
chr2_+_30441831 0.22 ENSMUST00000131476.1
protein phosphatase 2A, regulatory subunit B (PR 53)
chr9_+_7272514 0.22 ENSMUST00000015394.8
matrix metallopeptidase 13
chr7_-_4971168 0.21 ENSMUST00000133272.1
predicted gene 1078
chr5_-_107875035 0.20 ENSMUST00000138111.1
ENSMUST00000112642.1
ecotropic viral integration site 5
chr9_-_119977250 0.19 ENSMUST00000035101.7
cysteine-serine-rich nuclear protein 1
chr16_+_17561885 0.18 ENSMUST00000171002.1
ENSMUST00000023441.4
purinergic receptor P2X, ligand-gated ion channel, 6
chr6_+_29529277 0.18 ENSMUST00000163511.1
interferon regulatory factor 5
chr1_-_10719898 0.17 ENSMUST00000035577.6
carboxypeptidase A6
chr9_+_104566677 0.17 ENSMUST00000157006.1
copine IV
chr16_+_20548577 0.17 ENSMUST00000003319.5
ATP-binding cassette, sub-family F (GCN20), member 3
chr7_+_30763750 0.17 ENSMUST00000165887.1
ENSMUST00000085691.4
ENSMUST00000085688.4
ENSMUST00000054427.6
dermokine
chr10_-_64090241 0.17 ENSMUST00000133588.1
leucine rich repeat transmembrane neuronal 3
chr2_-_18048784 0.16 ENSMUST00000142856.1
SKI/DACH domain containing 1
chr18_+_40258361 0.16 ENSMUST00000091927.4
potassium channel tetramerisation domain containing 16
chr12_-_84194007 0.16 ENSMUST00000110294.1
ELM2 and Myb/SANT-like domain containing 1
chr9_+_7347374 0.16 ENSMUST00000065079.5
ENSMUST00000005950.5
matrix metallopeptidase 12
chr1_-_171240055 0.16 ENSMUST00000131286.1
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr18_-_31317043 0.16 ENSMUST00000139924.1
ENSMUST00000153060.1
Ras-like without CAAX 2
chr9_-_109059216 0.16 ENSMUST00000112053.1
three prime repair exonuclease 1
chr1_+_134560157 0.15 ENSMUST00000047714.7
lysine (K)-specific demethylase 5B
chr7_-_127946725 0.15 ENSMUST00000118755.1
ENSMUST00000094026.3
protease, serine, 36
chr1_-_12991109 0.14 ENSMUST00000115403.2
ENSMUST00000115402.1
solute carrier organic anion transporter family, member 5A1
chr18_-_43477764 0.14 ENSMUST00000057110.9
eukaryotic translation initiation factor 3, subunit J2
chr6_-_124769548 0.14 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
enolase 2, gamma neuronal
chr11_-_50210765 0.13 ENSMUST00000143379.1
ENSMUST00000015981.5
ENSMUST00000102774.4
sequestosome 1
chr11_+_61684419 0.13 ENSMUST00000093019.5
family with sequence similarity 83, member G
chr17_-_42742167 0.12 ENSMUST00000113614.2
G protein-coupled receptor 111
chr11_-_3914664 0.12 ENSMUST00000109995.1
ENSMUST00000051207.1
solute carrier family 35, member E4
chr4_-_19922599 0.12 ENSMUST00000029900.5
ATPase, H+ transporting, lysosomal V0 subunit D2
chr3_-_123034943 0.12 ENSMUST00000029761.7
myozenin 2
chr10_+_116143881 0.12 ENSMUST00000105271.2
protein tyrosine phosphatase, receptor type, R
chr7_+_26435614 0.12 ENSMUST00000119386.1
NLR family, pyrin domain containing 4A
chr17_+_47769191 0.12 ENSMUST00000160373.1
ENSMUST00000159641.1
transcription factor EB
chr10_-_64090265 0.11 ENSMUST00000105439.1
leucine rich repeat transmembrane neuronal 3
chr3_-_88177671 0.10 ENSMUST00000181837.1
RIKEN cDNA 1700113A16 gene
chr9_-_109059711 0.10 ENSMUST00000061973.4
three prime repair exonuclease 1
chr16_+_32400506 0.10 ENSMUST00000115149.2
transmembrane 4 L six family member 19
chr11_-_96075655 0.10 ENSMUST00000090541.5
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr15_-_76014318 0.10 ENSMUST00000060807.5
family with sequence similarity 83, member H
chr12_+_71015966 0.10 ENSMUST00000046305.5
AT rich interactive domain 4A (RBP1-like)
chr11_+_77801325 0.10 ENSMUST00000151373.2
ENSMUST00000172303.2
ENSMUST00000130305.2
ENSMUST00000164334.1
ENSMUST00000092884.4
myosin XVIIIA
chr11_+_77801291 0.09 ENSMUST00000100794.3
myosin XVIIIA
chr14_-_55758458 0.09 ENSMUST00000001497.7
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chr12_+_51690966 0.09 ENSMUST00000021338.8
adaptor-related protein complex AP-4, sigma 1
chr9_+_7464141 0.09 ENSMUST00000034492.5
matrix metallopeptidase 1a (interstitial collagenase)
chr11_-_96075581 0.09 ENSMUST00000107686.1
ENSMUST00000107684.1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr3_+_116878227 0.09 ENSMUST00000040260.6
ferric-chelate reductase 1
chr15_+_102503722 0.09 ENSMUST00000096145.4
predicted gene 10337
chr2_+_110721587 0.09 ENSMUST00000111017.2
mucin 15
chr8_+_4226827 0.08 ENSMUST00000053035.6
leucine rich repeat containing 8 family, member E
chr7_-_105787567 0.07 ENSMUST00000144189.1
dachsous 1 (Drosophila)
chr2_-_25224653 0.07 ENSMUST00000043584.4
tubulin, beta 4B class IVB
chr2_+_110721340 0.07 ENSMUST00000111016.2
mucin 15
chr7_+_30776394 0.06 ENSMUST00000041703.7
dermokine
chr11_-_109473598 0.06 ENSMUST00000070152.5
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr3_+_123267445 0.06 ENSMUST00000047923.7
Sec24 related gene family, member D (S. cerevisiae)
chr10_-_44458715 0.06 ENSMUST00000039174.4
PR domain containing 1, with ZNF domain
chr7_+_6045161 0.06 ENSMUST00000037728.5
ENSMUST00000121583.1
NLR family, pyrin domain containing 4C
chr15_+_101473472 0.06 ENSMUST00000088049.3
keratin 86
chr1_+_106861144 0.06 ENSMUST00000086701.6
ENSMUST00000112730.1
serine (or cysteine) peptidase inhibitor, clade B, member 5
chr1_+_120602405 0.06 ENSMUST00000079721.7
engrailed 1
chr3_+_55461758 0.06 ENSMUST00000070418.4
doublecortin-like kinase 1
chr18_+_42053692 0.06 ENSMUST00000074679.3
SH3 domain containing ring finger 2
chr13_-_113663670 0.05 ENSMUST00000054650.4
heat shock protein 3
chr11_+_4257557 0.05 ENSMUST00000066283.5
leukemia inhibitory factor
chr1_+_134560190 0.05 ENSMUST00000112198.1
ENSMUST00000112197.1
lysine (K)-specific demethylase 5B
chr9_+_96259246 0.04 ENSMUST00000179065.1
ENSMUST00000165768.2
transcription factor Dp 2
chr2_+_118663235 0.04 ENSMUST00000099557.3
p21 protein (Cdc42/Rac)-activated kinase 6
chr9_+_96258697 0.04 ENSMUST00000179416.1
transcription factor Dp 2
chr4_-_140665891 0.04 ENSMUST00000069623.5
Rho guanine nucleotide exchange factor (GEF) 10-like
chr6_+_42349826 0.03 ENSMUST00000070635.6
zyxin
chr1_+_182564994 0.03 ENSMUST00000048941.7
ENSMUST00000168514.1
calpain 8
chr11_+_117232254 0.03 ENSMUST00000106354.2
septin 9
chr17_+_78508063 0.03 ENSMUST00000024880.9
vitrin
chr14_+_27622433 0.03 ENSMUST00000090302.5
ELKS/RAB6-interacting/CAST family member 2
chr2_+_151572606 0.03 ENSMUST00000028950.8
syndecan binding protein (syntenin) 2
chr19_-_38125258 0.02 ENSMUST00000025951.6
retinol binding protein 4, plasma
chr12_+_83632208 0.02 ENSMUST00000048155.9
ENSMUST00000182618.1
ENSMUST00000183154.1
ENSMUST00000182036.1
ENSMUST00000182347.1
RNA binding motif protein 25
chr16_-_4880284 0.01 ENSMUST00000037843.6
UBA-like domain containing 1
chr13_+_30659999 0.01 ENSMUST00000091672.6
ENSMUST00000110310.1
ENSMUST00000095914.5
dual specificity phosphatase 22
chr6_+_42350000 0.01 ENSMUST00000164375.1
zyxin
chr2_+_152105722 0.00 ENSMUST00000099225.2
sulfiredoxin 1 homolog (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of Fosb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0044805 late nucleophagy(GO:0044805)
0.2 0.5 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 1.0 GO:0015862 uridine transport(GO:0015862)
0.1 0.7 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 1.3 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 0.4 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.1 0.2 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.1 0.3 GO:0090472 dibasic protein processing(GO:0090472)
0.1 0.3 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.1 0.5 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.2 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.0 0.2 GO:0035938 estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864)
0.0 0.3 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.2 GO:1903027 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.0 0.4 GO:1902572 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.3 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.0 0.2 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.3 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0005638 lamin filament(GO:0005638)
0.1 0.3 GO:0005914 spot adherens junction(GO:0005914)
0.0 0.8 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.2 GO:0097447 dendritic tree(GO:0097447)
0.0 0.3 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.4 GO:0042599 lamellar body(GO:0042599)
0.0 0.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 1.0 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling