Motif ID: Gata2_Gata1

Z-value: 4.260

Transcription factors associated with Gata2_Gata1:

Gene SymbolEntrez IDGene Name
Gata1 ENSMUSG00000031162.8 Gata1
Gata2 ENSMUSG00000015053.8 Gata2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gata1mm10_v2_chrX_-_7964166_79641910.892.4e-13Click!
Gata2mm10_v2_chr6_+_88198656_881986750.833.6e-10Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gata2_Gata1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_26199008 69.407 ENSMUST00000142410.1
ENSMUST00000120333.1
ENSMUST00000039113.7
Pdia2


protein disulfide isomerase associated 2


chr4_-_46404224 64.495 ENSMUST00000107764.2
Hemgn
hemogen
chr6_+_41458923 59.969 ENSMUST00000031910.7
Prss1
protease, serine, 1 (trypsin 1)
chr2_+_84980458 57.878 ENSMUST00000028467.5
Prg2
proteoglycan 2, bone marrow
chr2_-_121036750 55.992 ENSMUST00000023987.5
Epb4.2
erythrocyte protein band 4.2
chr11_+_32276400 54.814 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr6_+_30639218 54.605 ENSMUST00000031806.9
Cpa1
carboxypeptidase A1, pancreatic
chr6_-_41704339 52.840 ENSMUST00000031899.8
Kel
Kell blood group
chr6_+_41392356 52.670 ENSMUST00000049079.7
Gm5771
predicted gene 5771
chr8_+_84701430 51.742 ENSMUST00000037165.4
Lyl1
lymphoblastomic leukemia 1
chr2_-_121037048 50.084 ENSMUST00000102490.3
Epb4.2
erythrocyte protein band 4.2
chr17_-_35085609 47.501 ENSMUST00000038507.6
Ly6g6f
lymphocyte antigen 6 complex, locus G6F
chr17_+_36869567 47.364 ENSMUST00000060524.9
Trim10
tripartite motif-containing 10
chr3_-_84479418 45.162 ENSMUST00000091002.1
Fhdc1
FH2 domain containing 1
chrX_-_7964166 45.086 ENSMUST00000128449.1
Gata1
GATA binding protein 1
chr5_-_73191848 44.936 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr1_-_132367879 44.727 ENSMUST00000142609.1
Tmcc2
transmembrane and coiled-coil domains 2
chr11_+_32276893 43.450 ENSMUST00000145569.1
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr17_-_28560704 42.197 ENSMUST00000114785.1
ENSMUST00000025062.3
Clps

colipase, pancreatic

chr8_-_85380964 41.405 ENSMUST00000122452.1
Mylk3
myosin light chain kinase 3
chr9_+_21029373 41.089 ENSMUST00000001040.5
Icam4
intercellular adhesion molecule 4, Landsteiner-Wiener blood group
chr6_+_30541582 40.983 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr14_+_27000362 38.939 ENSMUST00000035433.8
Hesx1
homeobox gene expressed in ES cells
chr11_-_83286722 38.864 ENSMUST00000163961.2
Slfn14
schlafen family member 14
chr17_-_35066170 38.731 ENSMUST00000174190.1
ENSMUST00000097337.1
AU023871

expressed sequence AU023871

chr4_+_134864536 38.463 ENSMUST00000030627.7
Rhd
Rh blood group, D antigen
chr18_-_78123324 37.981 ENSMUST00000160292.1
ENSMUST00000091813.5
Slc14a1

solute carrier family 14 (urea transporter), member 1

chr4_-_137430517 37.429 ENSMUST00000102522.4
Cela3b
chymotrypsin-like elastase family, member 3B
chr6_+_86078070 37.279 ENSMUST00000032069.5
Add2
adducin 2 (beta)
chr3_-_20242173 37.104 ENSMUST00000001921.1
Cpa3
carboxypeptidase A3, mast cell
chr15_-_103251465 33.668 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
Nfe2




nuclear factor, erythroid derived 2




chr10_-_62342674 33.443 ENSMUST00000143179.1
ENSMUST00000130422.1
Hk1

hexokinase 1

chr8_+_84901928 32.252 ENSMUST00000067060.7
Klf1
Kruppel-like factor 1 (erythroid)
chr7_-_4397705 32.098 ENSMUST00000108590.2
Gp6
glycoprotein 6 (platelet)
chr9_-_21963568 31.314 ENSMUST00000006397.5
Epor
erythropoietin receptor
chr6_+_41302265 30.907 ENSMUST00000031913.4
Try4
trypsin 4
chr10_-_80421847 30.434 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr7_-_99238564 28.395 ENSMUST00000064231.7
Mogat2
monoacylglycerol O-acyltransferase 2
chr5_+_115466234 28.030 ENSMUST00000145785.1
ENSMUST00000031495.4
ENSMUST00000112071.1
ENSMUST00000125568.1
Pla2g1b



phospholipase A2, group IB, pancreas



chr2_+_103957976 26.839 ENSMUST00000156813.1
ENSMUST00000170926.1
Lmo2

LIM domain only 2

chr7_-_100467149 26.504 ENSMUST00000184420.1
RP23-308M1.2
RP23-308M1.2
chr16_+_38362205 25.313 ENSMUST00000023494.6
Popdc2
popeye domain containing 2
chrX_+_93675088 24.018 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr11_+_95337012 23.533 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr11_-_87359011 23.469 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr6_-_41314700 23.329 ENSMUST00000064324.5
Try5
trypsin 5
chr16_+_38362234 22.451 ENSMUST00000114739.1
Popdc2
popeye domain containing 2
chr4_-_137409777 22.412 ENSMUST00000024200.6
Gm13011
predicted gene 13011
chr1_+_40429563 22.241 ENSMUST00000174335.1
Il1rl1
interleukin 1 receptor-like 1
chr11_-_116076986 22.228 ENSMUST00000153408.1
Unc13d
unc-13 homolog D (C. elegans)
chr11_-_102469839 22.027 ENSMUST00000103086.3
Itga2b
integrin alpha 2b
chr17_-_25944932 21.583 ENSMUST00000085027.3
Nhlrc4
NHL repeat containing 4
chr4_+_119637704 21.056 ENSMUST00000024015.2
Guca2a
guanylate cyclase activator 2a (guanylin)
chr6_-_122609964 20.949 ENSMUST00000032211.4
Gdf3
growth differentiation factor 3
chr11_-_99438143 19.949 ENSMUST00000017743.2
Krt20
keratin 20
chrX_-_107403295 19.756 ENSMUST00000033591.5
Itm2a
integral membrane protein 2A
chr4_-_119189949 19.527 ENSMUST00000124626.1
Ermap
erythroblast membrane-associated protein
chr7_+_28540863 19.215 ENSMUST00000119180.2
Sycn
syncollin
chr8_-_85365341 18.995 ENSMUST00000121972.1
Mylk3
myosin light chain kinase 3
chr8_-_85365317 18.989 ENSMUST00000034133.7
Mylk3
myosin light chain kinase 3
chr19_-_7019423 18.979 ENSMUST00000040772.8
Fermt3
fermitin family homolog 3 (Drosophila)
chr4_+_13751297 18.503 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_153241402 18.101 ENSMUST00000056924.7
Plagl2
pleiomorphic adenoma gene-like 2
chr3_+_108364882 16.037 ENSMUST00000090563.5
Mybphl
myosin binding protein H-like
chr4_+_40920047 15.955 ENSMUST00000030122.4
Spink4
serine peptidase inhibitor, Kazal type 4
chr9_-_44342332 14.947 ENSMUST00000097558.3
Hmbs
hydroxymethylbilane synthase
chr13_-_55528511 14.720 ENSMUST00000047877.4
Dok3
docking protein 3
chr7_+_110773658 13.873 ENSMUST00000143786.1
Ampd3
adenosine monophosphate deaminase 3
chr15_+_80623499 13.748 ENSMUST00000043149.7
Grap2
GRB2-related adaptor protein 2
chr15_+_57985873 13.337 ENSMUST00000050374.2
Fam83a
family with sequence similarity 83, member A
chr19_+_10015016 13.191 ENSMUST00000137637.1
ENSMUST00000149967.1
Rab3il1

RAB3A interacting protein (rabin3)-like 1

chr3_-_107221722 13.143 ENSMUST00000029504.8
Cym
chymosin
chr4_-_119190005 13.028 ENSMUST00000138395.1
ENSMUST00000156746.1
Ermap

erythroblast membrane-associated protein

chr14_+_75455957 12.696 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr11_-_116077954 11.769 ENSMUST00000106451.1
ENSMUST00000075036.2
Unc13d

unc-13 homolog D (C. elegans)

chr1_-_173333503 11.534 ENSMUST00000038227.4
Darc
Duffy blood group, chemokine receptor
chr11_-_116077562 11.299 ENSMUST00000174822.1
Unc13d
unc-13 homolog D (C. elegans)
chr2_+_72476225 11.068 ENSMUST00000157019.1
Cdca7
cell division cycle associated 7
chrX_+_150547375 11.067 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr11_-_116077927 11.030 ENSMUST00000156545.1
Unc13d
unc-13 homolog D (C. elegans)
chr2_+_72476159 11.011 ENSMUST00000102691.4
Cdca7
cell division cycle associated 7
chr10_-_62327757 10.975 ENSMUST00000139228.1
Hk1
hexokinase 1
chr11_-_116077606 10.527 ENSMUST00000106450.1
Unc13d
unc-13 homolog D (C. elegans)
chr7_-_119459266 10.479 ENSMUST00000033255.5
Gp2
glycoprotein 2 (zymogen granule membrane)
chr11_+_70639118 10.435 ENSMUST00000055184.6
ENSMUST00000108551.2
Gp1ba

glycoprotein 1b, alpha polypeptide

chr19_-_10678001 10.332 ENSMUST00000025647.5
Pga5
pepsinogen 5, group I
chr11_+_70505244 10.309 ENSMUST00000019063.2
Tm4sf5
transmembrane 4 superfamily member 5
chr1_+_75507077 9.329 ENSMUST00000037330.4
Inha
inhibin alpha
chr17_-_33713372 9.059 ENSMUST00000173392.1
March2
membrane-associated ring finger (C3HC4) 2
chr13_-_73700721 9.044 ENSMUST00000022048.5
Slc6a19
solute carrier family 6 (neurotransmitter transporter), member 19
chr6_-_136922169 8.633 ENSMUST00000032343.6
Erp27
endoplasmic reticulum protein 27
chr3_-_75270073 8.628 ENSMUST00000039047.4
Serpini2
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr6_+_87428986 8.297 ENSMUST00000032125.5
Bmp10
bone morphogenetic protein 10
chr7_+_28833975 8.006 ENSMUST00000066723.8
Lgals4
lectin, galactose binding, soluble 4
chr3_+_79884576 7.969 ENSMUST00000145992.1
Fam198b
family with sequence similarity 198, member B
chr11_+_87760533 7.481 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr10_+_80019621 7.368 ENSMUST00000043311.6
Hmha1
histocompatibility (minor) HA-1
chr11_-_94242701 7.100 ENSMUST00000061469.3
Wfikkn2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr16_+_44943678 6.968 ENSMUST00000114613.2
ENSMUST00000114612.1
ENSMUST00000077178.6
ENSMUST00000048479.7
ENSMUST00000114611.3
ENSMUST00000164007.1
ENSMUST00000171779.1
Cd200r3






CD200 receptor 3






chr11_+_4986824 6.843 ENSMUST00000009234.9
ENSMUST00000109897.1
Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr1_-_138175238 6.815 ENSMUST00000182536.1
Ptprc
protein tyrosine phosphatase, receptor type, C
chr6_+_125552948 6.609 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr8_+_120488416 6.458 ENSMUST00000034279.9
Gse1
genetic suppressor element 1
chr7_-_141655319 6.445 ENSMUST00000062451.7
Muc6
mucin 6, gastric
chr6_-_136941887 6.412 ENSMUST00000111891.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr1_-_138175283 6.230 ENSMUST00000182755.1
ENSMUST00000183262.1
ENSMUST00000027645.7
ENSMUST00000112036.2
ENSMUST00000182283.1
Ptprc




protein tyrosine phosphatase, receptor type, C




chr1_-_138175126 6.086 ENSMUST00000183301.1
Ptprc
protein tyrosine phosphatase, receptor type, C
chr3_+_105904377 5.731 ENSMUST00000000574.1
Adora3
adenosine A3 receptor
chr9_+_66350465 5.503 ENSMUST00000042824.6
Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr2_+_164403194 5.089 ENSMUST00000017151.1
Rbpjl
recombination signal binding protein for immunoglobulin kappa J region-like
chr4_+_150148905 5.082 ENSMUST00000059893.7
Slc2a7
solute carrier family 2 (facilitated glucose transporter), member 7
chr6_-_136941494 4.967 ENSMUST00000111892.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr15_+_76904070 4.924 ENSMUST00000004072.8
Rpl8
ribosomal protein L8
chr6_-_136941694 4.821 ENSMUST00000032344.5
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr9_-_32541589 4.538 ENSMUST00000016231.7
Fli1
Friend leukemia integration 1
chr19_-_6015152 4.229 ENSMUST00000025891.8
Capn1
calpain 1
chr17_+_46650328 4.159 ENSMUST00000043464.7
Cul7
cullin 7
chr11_-_99322943 3.888 ENSMUST00000038004.2
Krt25
keratin 25
chr8_+_120537423 3.719 ENSMUST00000118136.1
Gse1
genetic suppressor element 1
chr3_+_79884496 3.691 ENSMUST00000118853.1
Fam198b
family with sequence similarity 198, member B
chr15_-_98607611 3.667 ENSMUST00000096224.4
Adcy6
adenylate cyclase 6
chr18_+_76059458 3.664 ENSMUST00000167921.1
Zbtb7c
zinc finger and BTB domain containing 7C
chr10_+_69785507 3.520 ENSMUST00000182993.1
Ank3
ankyrin 3, epithelial
chrX_-_73869804 3.433 ENSMUST00000066576.5
ENSMUST00000114430.1
L1cam

L1 cell adhesion molecule

chr19_-_6015769 3.431 ENSMUST00000164843.1
Capn1
calpain 1
chr2_-_33087169 3.370 ENSMUST00000102810.3
Garnl3
GTPase activating RANGAP domain-like 3
chr3_-_14808358 3.366 ENSMUST00000181860.1
ENSMUST00000144327.2
Car1

carbonic anhydrase 1

chr17_+_32621319 3.348 ENSMUST00000077639.5
Gm9705
predicted gene 9705
chr3_-_63851251 3.316 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr11_-_26591729 3.206 ENSMUST00000109504.1
Vrk2
vaccinia related kinase 2
chr2_+_131133497 3.087 ENSMUST00000110225.1
Gm11037
predicted gene 11037
chr19_-_10482874 3.070 ENSMUST00000038842.3
Ppp1r32
protein phosphatase 1, regulatory subunit 32
chr11_+_90030295 2.934 ENSMUST00000092788.3
Tmem100
transmembrane protein 100
chr17_-_31144271 2.855 ENSMUST00000024826.7
Tff2
trefoil factor 2 (spasmolytic protein 1)
chr11_-_86357570 2.841 ENSMUST00000043624.8
Med13
mediator complex subunit 13
chr16_-_63864114 2.831 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr4_-_32923455 2.337 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr7_-_98112618 2.265 ENSMUST00000153657.1
Myo7a
myosin VIIA
chr7_-_135528645 2.122 ENSMUST00000053716.7
Clrn3
clarin 3
chr3_-_144819494 2.071 ENSMUST00000029929.7
Clca2
chloride channel calcium activated 2
chr14_+_66784523 2.055 ENSMUST00000071522.2
Gm10032
predicted gene 10032
chr1_+_191025350 2.026 ENSMUST00000181050.1
A230020J21Rik
RIKEN cDNA A230020J21 gene
chr6_+_129397478 1.950 ENSMUST00000112081.2
ENSMUST00000112079.2
Clec1b

C-type lectin domain family 1, member b

chr3_-_94473591 1.950 ENSMUST00000029785.3
Riiad1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
chr10_+_116177351 1.872 ENSMUST00000155606.1
ENSMUST00000128399.1
Ptprr

protein tyrosine phosphatase, receptor type, R

chr2_-_33086366 1.863 ENSMUST00000049618.2
Garnl3
GTPase activating RANGAP domain-like 3
chrX_-_7572843 1.795 ENSMUST00000132788.1
Ppp1r3f
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr3_+_138352378 1.724 ENSMUST00000090166.4
Adh6b
alcohol dehydrogenase 6B (class V)
chr3_+_96596628 1.679 ENSMUST00000058943.7
Ankrd34a
ankyrin repeat domain 34A
chrX_+_73757069 1.632 ENSMUST00000002079.6
Plxnb3
plexin B3
chr14_-_54653616 1.630 ENSMUST00000126166.1
ENSMUST00000141453.1
ENSMUST00000150371.1
ENSMUST00000123875.1
ENSMUST00000022794.7
ENSMUST00000148754.3
Acin1





apoptotic chromatin condensation inducer 1





chr11_-_53707269 1.627 ENSMUST00000124352.1
ENSMUST00000020649.7
Rad50

RAD50 homolog (S. cerevisiae)

chrX_+_166238901 1.623 ENSMUST00000112235.1
Gpm6b
glycoprotein m6b
chr16_+_25801907 1.622 ENSMUST00000040231.6
ENSMUST00000115306.1
ENSMUST00000115304.1
ENSMUST00000115305.1
Trp63



transformation related protein 63



chr2_+_32525013 1.604 ENSMUST00000150621.1
Gm13412
predicted gene 13412
chr11_+_96024540 1.573 ENSMUST00000103157.3
Gip
gastric inhibitory polypeptide
chr12_-_69893162 1.559 ENSMUST00000049239.7
ENSMUST00000110570.1
Map4k5

mitogen-activated protein kinase kinase kinase kinase 5

chr3_-_102782708 1.529 ENSMUST00000029450.3
ENSMUST00000172026.1
ENSMUST00000170856.1
Tshb


thyroid stimulating hormone, beta subunit


chr2_-_25224653 1.401 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr5_+_24364804 1.371 ENSMUST00000030834.4
ENSMUST00000115090.1
Nos3

nitric oxide synthase 3, endothelial cell

chr6_-_71632897 1.272 ENSMUST00000065509.4
Kdm3a
lysine (K)-specific demethylase 3A
chr4_-_59438633 1.208 ENSMUST00000040166.7
ENSMUST00000107544.1
Susd1

sushi domain containing 1

chr10_-_130127055 1.159 ENSMUST00000074161.1
Olfr824
olfactory receptor 824
chr2_-_7081207 1.157 ENSMUST00000114923.2
ENSMUST00000182706.1
Celf2

CUGBP, Elav-like family member 2

chr11_-_75169519 1.122 ENSMUST00000055619.4
Hic1
hypermethylated in cancer 1
chrX_+_10485121 1.041 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr10_+_116177217 0.935 ENSMUST00000148731.1
Ptprr
protein tyrosine phosphatase, receptor type, R
chr10_+_5593718 0.907 ENSMUST00000051809.8
Myct1
myc target 1
chr3_-_146839365 0.896 ENSMUST00000084614.3
Gm10288
predicted gene 10288
chr8_+_105636509 0.859 ENSMUST00000005841.9
Ctcf
CCCTC-binding factor
chr2_-_7081256 0.829 ENSMUST00000183209.1
Celf2
CUGBP, Elav-like family member 2
chr10_-_13388830 0.806 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chrX_-_95478107 0.778 ENSMUST00000033549.2
Asb12
ankyrin repeat and SOCS box-containing 12
chr9_-_44713196 0.749 ENSMUST00000144251.1
ENSMUST00000156918.1
Phldb1

pleckstrin homology-like domain, family B, member 1

chr2_+_32621750 0.720 ENSMUST00000113278.2
Ak1
adenylate kinase 1
chr6_+_129397297 0.709 ENSMUST00000032262.7
Clec1b
C-type lectin domain family 1, member b
chr18_-_43477764 0.697 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr7_+_45413657 0.597 ENSMUST00000058879.6
Ntf5
neurotrophin 5
chr2_-_13011747 0.594 ENSMUST00000061545.5
C1ql3
C1q-like 3
chr3_-_59262825 0.572 ENSMUST00000050360.7
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr7_-_44892358 0.523 ENSMUST00000003049.6
Med25
mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)
chr2_-_26246707 0.515 ENSMUST00000166349.1
C030048H21Rik
RIKEN cDNA C030048H21 gene
chr16_-_29544852 0.449 ENSMUST00000039090.8
Atp13a4
ATPase type 13A4
chr5_-_83355120 0.448 ENSMUST00000053543.4
Tecrl
trans-2,3-enoyl-CoA reductase-like
chr8_+_74872692 0.417 ENSMUST00000034034.3
Isx
intestine specific homeobox
chr6_+_24597754 0.388 ENSMUST00000031694.6
Lmod2
leiomodin 2 (cardiac)
chr6_-_132957919 0.382 ENSMUST00000082085.4
Tas2r131
taste receptor, type 2, member 131
chr8_-_4325096 0.352 ENSMUST00000098950.4
Elavl1
ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)
chr15_-_77153772 0.325 ENSMUST00000166610.1
ENSMUST00000111581.2
Rbfox2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr3_+_90072641 0.322 ENSMUST00000121503.1
ENSMUST00000119570.1
ENSMUST00000062193.9
Tpm3


tropomyosin 3, gamma


chr2_-_60722636 0.320 ENSMUST00000028348.2
ENSMUST00000112517.1
Itgb6

integrin beta 6

chrX_-_134111708 0.304 ENSMUST00000159259.1
ENSMUST00000113275.3
Nox1

NADPH oxidase 1

chr4_-_14621805 0.292 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr19_+_38264761 0.281 ENSMUST00000087252.5
Lgi1
leucine-rich repeat LGI family, member 1
chr11_-_61453992 0.274 ENSMUST00000060255.7
ENSMUST00000054927.7
ENSMUST00000102661.3
Rnf112


ring finger protein 112


chr1_+_172341197 0.218 ENSMUST00000056136.3
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr3_+_79884931 0.198 ENSMUST00000135021.1
Fam198b
family with sequence similarity 198, member B
chr12_+_95692212 0.190 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr9_-_77251829 0.178 ENSMUST00000184322.1
ENSMUST00000184316.1
Mlip

muscular LMNA-interacting protein

chr5_+_64159429 0.153 ENSMUST00000043893.6
Tbc1d1
TBC1 domain family, member 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
19.3 57.9 GO:0002215 defense response to nematode(GO:0002215)
15.0 45.1 GO:0030221 basophil differentiation(GO:0030221)
13.2 79.4 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
12.3 98.3 GO:0015671 oxygen transport(GO:0015671)
10.4 31.3 GO:0036018 response to erythropoietin(GO:0036017) cellular response to erythropoietin(GO:0036018) erythropoietin-mediated signaling pathway(GO:0038162)
9.5 28.4 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
9.3 28.0 GO:0044240 multicellular organismal lipid catabolic process(GO:0044240)
8.8 52.8 GO:0031133 regulation of axon diameter(GO:0031133)
8.4 66.9 GO:0061789 dense core granule priming(GO:0061789)
8.0 47.8 GO:0060931 sinoatrial node cell development(GO:0060931)
7.4 51.7 GO:0001955 blood vessel maturation(GO:0001955)
5.6 22.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
5.4 38.0 GO:0071918 urea transmembrane transport(GO:0071918)
5.3 69.4 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
4.5 44.9 GO:0090527 actin filament reorganization(GO:0090527)
4.3 21.5 GO:0048859 formation of anatomical boundary(GO:0048859)
3.9 38.9 GO:0030916 otic vesicle formation(GO:0030916)
3.8 19.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
3.8 30.4 GO:0002326 B cell lineage commitment(GO:0002326)
3.7 44.4 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
3.3 19.8 GO:0002317 plasma cell differentiation(GO:0002317)
2.9 37.1 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
2.8 33.7 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
2.7 32.3 GO:0043249 erythrocyte maturation(GO:0043249)
2.5 12.7 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
2.4 26.8 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
2.4 30.9 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
2.4 19.0 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
2.3 16.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
2.2 38.9 GO:0016075 rRNA catabolic process(GO:0016075)
2.1 49.0 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
2.1 10.5 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
1.9 9.3 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
1.6 1.6 GO:0060529 squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
1.6 32.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
1.6 23.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
1.5 13.9 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
1.5 24.0 GO:0006657 CDP-choline pathway(GO:0006657)
1.5 37.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
1.4 22.4 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
1.3 7.7 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
1.2 14.9 GO:0018065 protein-cofactor linkage(GO:0018065)
0.9 2.8 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.9 23.0 GO:0045109 intermediate filament organization(GO:0045109)
0.9 3.4 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.8 12.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.8 37.8 GO:0032094 response to food(GO:0032094)
0.8 11.1 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.7 44.7 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.6 5.7 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.6 7.2 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660)
0.6 7.7 GO:0097264 self proteolysis(GO:0097264)
0.5 2.9 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.5 2.8 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.4 10.4 GO:0042730 fibrinolysis(GO:0042730)
0.4 1.6 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.4 2.9 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.4 3.2 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.3 1.3 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.3 5.5 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.3 18.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.3 1.6 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.3 1.6 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.3 4.5 GO:0035855 megakaryocyte development(GO:0035855)
0.3 3.7 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.3 2.3 GO:0048563 post-embryonic animal organ morphogenesis(GO:0048563)
0.2 18.0 GO:0070527 platelet aggregation(GO:0070527)
0.2 1.6 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.2 17.8 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.2 0.9 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.2 5.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 13.7 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 2.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 2.7 GO:0030220 platelet formation(GO:0030220)
0.2 6.6 GO:0030168 platelet activation(GO:0030168)
0.2 9.0 GO:0015804 neutral amino acid transport(GO:0015804)
0.2 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.2 9.9 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.2 4.2 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.1 1.8 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.1 0.4 GO:1901738 regulation of vitamin A metabolic process(GO:1901738)
0.1 19.0 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.1 249.0 GO:0006508 proteolysis(GO:0006508)
0.1 0.7 GO:0046103 ADP biosynthetic process(GO:0006172) inosine biosynthetic process(GO:0046103)
0.1 2.8 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.1 0.7 GO:2001197 regulation of basement membrane organization(GO:0110011) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 3.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 1.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 4.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.3 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 0.2 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.1 2.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.4 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 18.9 GO:0006887 exocytosis(GO:0006887) vesicle fusion to plasma membrane(GO:0099500) exocytic process(GO:0140029)
0.0 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 3.3 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.5 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.4 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.9 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.4 GO:0090662 ATP hydrolysis coupled transmembrane transport(GO:0090662) ATP hydrolysis coupled ion transmembrane transport(GO:0099131) ATP hydrolysis coupled cation transmembrane transport(GO:0099132)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
12.3 98.3 GO:0005833 hemoglobin complex(GO:0005833)
6.6 72.9 GO:0033093 Weibel-Palade body(GO:0033093)
3.7 37.3 GO:0008290 F-actin capping protein complex(GO:0008290)
3.1 9.3 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
2.9 32.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
1.4 44.4 GO:0097228 sperm principal piece(GO:0097228)
0.8 30.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.6 4.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.5 22.3 GO:0008305 integrin complex(GO:0008305)
0.5 12.7 GO:0005859 muscle myosin complex(GO:0005859)
0.5 10.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.4 1.6 GO:0030870 Mre11 complex(GO:0030870)
0.4 74.4 GO:0032993 protein-DNA complex(GO:0032993)
0.3 15.9 GO:0002102 podosome(GO:0002102)
0.3 2.3 GO:0002139 stereocilia coupling link(GO:0002139)
0.2 56.3 GO:0042383 sarcolemma(GO:0042383)
0.2 81.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.2 18.7 GO:0030667 secretory granule membrane(GO:0030667)
0.2 1.6 GO:0061574 ASAP complex(GO:0061574)
0.2 18.5 GO:0016363 nuclear matrix(GO:0016363)
0.2 17.9 GO:0005882 intermediate filament(GO:0005882)
0.1 1.4 GO:0045298 tubulin complex(GO:0045298)
0.1 35.5 GO:0030427 site of polarized growth(GO:0030427)
0.1 5.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.7 GO:0045180 basal cortex(GO:0045180)
0.1 5.7 GO:0042629 mast cell granule(GO:0042629)
0.1 0.2 GO:0071437 invadopodium(GO:0071437) invadopodium membrane(GO:0071438)
0.1 4.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 25.5 GO:0030141 secretory granule(GO:0030141)
0.1 13.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 332.9 GO:0005615 extracellular space(GO:0005615)
0.1 15.9 GO:0000793 condensed chromosome(GO:0000793)
0.1 2.8 GO:0016592 mediator complex(GO:0016592) core mediator complex(GO:0070847)
0.1 0.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 35.3 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 11.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 40.3 GO:0005730 nucleolus(GO:0005730)
0.0 1.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 2.9 GO:0043204 perikaryon(GO:0043204)
0.0 22.5 GO:0097708 cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708)
0.0 2.8 GO:0005769 early endosome(GO:0005769)
0.0 0.5 GO:0005581 collagen trimer(GO:0005581)
0.0 1.6 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.5 GO:0044798 nuclear transcription factor complex(GO:0044798)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
12.3 98.3 GO:0005344 oxygen transporter activity(GO:0005344)
9.9 79.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
6.3 38.0 GO:0015265 urea channel activity(GO:0015265)
6.3 69.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
5.7 28.4 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
5.6 22.2 GO:0002114 interleukin-33 binding(GO:0002113) interleukin-33 receptor activity(GO:0002114)
4.9 44.4 GO:0008865 fructokinase activity(GO:0008865)
4.8 24.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
4.4 22.0 GO:0070051 fibrinogen binding(GO:0070051)
4.2 21.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
4.1 132.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
3.8 30.4 GO:0070644 vitamin D response element binding(GO:0070644)
3.7 11.1 GO:0016748 succinyltransferase activity(GO:0016748)
3.1 28.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
2.7 32.1 GO:0038064 collagen receptor activity(GO:0038064)
2.5 14.9 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
2.0 16.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
2.0 43.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
1.5 13.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.2 38.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
1.1 8.0 GO:0016936 galactoside binding(GO:0016936)
1.1 3.3 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
1.0 47.8 GO:0030552 cAMP binding(GO:0030552)
1.0 9.3 GO:0034711 inhibin binding(GO:0034711)
0.8 12.7 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.8 8.3 GO:0031433 telethonin binding(GO:0031433)
0.7 30.9 GO:0050699 WW domain binding(GO:0050699)
0.7 13.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.6 43.1 GO:0030507 spectrin binding(GO:0030507)
0.6 3.7 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.6 23.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.6 6.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.5 19.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.5 38.7 GO:0043022 ribosome binding(GO:0043022)
0.5 7.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.5 68.5 GO:0005178 integrin binding(GO:0005178)
0.5 26.8 GO:0070888 E-box binding(GO:0070888)
0.5 155.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.5 1.4 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.4 1.8 GO:2001069 glycogen binding(GO:2001069)
0.4 45.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.4 3.4 GO:0004064 arylesterase activity(GO:0004064)
0.4 13.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.4 2.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.3 66.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.3 7.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 1.6 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.3 2.8 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.3 12.8 GO:0005158 insulin receptor binding(GO:0005158)
0.2 13.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 2.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 37.1 GO:0047485 protein N-terminus binding(GO:0047485)
0.2 1.6 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.2 16.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 9.0 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 43.1 GO:0030246 carbohydrate binding(GO:0030246)
0.1 10.5 GO:0003823 antigen binding(GO:0003823)
0.1 14.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 1.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.6 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 2.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229) intracellular chloride channel activity(GO:0061778)
0.1 3.7 GO:0001540 amyloid-beta binding(GO:0001540)
0.1 4.9 GO:0019843 rRNA binding(GO:0019843)
0.1 0.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 28.4 GO:0008047 enzyme activator activity(GO:0008047)
0.1 22.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 5.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 8.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 2.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 2.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.8 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 2.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 8.1 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.7 GO:0005549 odorant binding(GO:0005549)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 57.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
1.2 40.0 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.9 22.3 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.9 69.6 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.9 13.7 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.8 66.1 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.5 19.1 PID_BCR_5PATHWAY BCR signaling pathway
0.4 28.0 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.3 15.4 PID_EPO_PATHWAY EPO signaling pathway
0.2 23.0 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.2 16.2 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.2 20.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.2 54.3 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 3.7 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.2 7.2 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.1 2.8 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 1.4 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.1 3.9 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.6 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 6.8 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.0 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.3 PID_AR_PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 28.6 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
1.5 44.0 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
1.4 28.0 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
1.3 41.6 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
1.2 10.9 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.9 13.5 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.9 21.7 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.9 41.1 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.9 19.7 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.8 10.4 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.8 39.9 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.7 13.9 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.7 29.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.7 13.7 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.5 5.1 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.4 5.7 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.4 60.4 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.3 6.3 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.3 6.4 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 3.7 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.2 7.0 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 18.2 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.4 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.4 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.6 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 4.9 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 5.1 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.7 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.6 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions