Motif ID: Gfi1_Gfi1b

Z-value: 1.271

Transcription factors associated with Gfi1_Gfi1b:

Gene SymbolEntrez IDGene Name
Gfi1 ENSMUSG00000029275.11 Gfi1
Gfi1b ENSMUSG00000026815.8 Gfi1b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gfi1mm10_v2_chr5_-_107723954_107723974-0.811.5e-09Click!
Gfi1bmm10_v2_chr2_-_28621932_28621982-0.812.1e-09Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gfi1_Gfi1b

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_127759780 10.756 ENSMUST00000128247.1
RP23-386P10.11
Protein Rdh9
chr5_-_87091150 7.788 ENSMUST00000154455.1
Ugt2b36
UDP glucuronosyltransferase 2 family, polypeptide B36
chr6_+_121838514 7.339 ENSMUST00000032228.8
Mug1
murinoglobulin 1
chr6_+_122006798 6.686 ENSMUST00000081777.6
Mug2
murinoglobulin 2
chr8_+_46010596 6.007 ENSMUST00000110381.2
Lrp2bp
Lrp2 binding protein
chr15_+_6445320 5.448 ENSMUST00000022749.9
C9
complement component 9
chr6_-_127109517 4.950 ENSMUST00000039913.8
9630033F20Rik
RIKEN cDNA 9630033F20 gene
chr10_-_127370535 4.747 ENSMUST00000026472.8
Inhbc
inhibin beta-C
chr5_+_90891234 4.608 ENSMUST00000031327.8
Cxcl1
chemokine (C-X-C motif) ligand 1
chr1_+_167618246 4.485 ENSMUST00000111380.1
Rxrg
retinoid X receptor gamma
chr16_-_46010212 4.460 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr10_-_128960965 4.374 ENSMUST00000026398.3
Mettl7b
methyltransferase like 7B
chr3_+_138415484 3.960 ENSMUST00000161312.1
ENSMUST00000013458.8
Adh4

alcohol dehydrogenase 4 (class II), pi polypeptide

chr4_-_49408042 3.935 ENSMUST00000081541.2
Acnat2
acyl-coenzyme A amino acid N-acyltransferase 2
chr14_+_55560904 3.907 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr3_-_98630309 3.864 ENSMUST00000044094.4
Hsd3b5
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5
chr11_+_101367542 3.810 ENSMUST00000019469.2
G6pc
glucose-6-phosphatase, catalytic
chr4_-_108118504 3.639 ENSMUST00000149106.1
Scp2
sterol carrier protein 2, liver
chr8_-_117673682 3.601 ENSMUST00000173522.1
ENSMUST00000174450.1
Sdr42e1

short chain dehydrogenase/reductase family 42E, member 1

chr7_+_51878967 3.467 ENSMUST00000051912.6
Gas2
growth arrest specific 2
chr1_+_60908993 3.371 ENSMUST00000027164.2
Ctla4
cytotoxic T-lymphocyte-associated protein 4
chr19_-_20727533 3.369 ENSMUST00000025656.3
Aldh1a7
aldehyde dehydrogenase family 1, subfamily A7
chr1_+_93512079 3.357 ENSMUST00000120301.1
ENSMUST00000041983.4
ENSMUST00000122402.1
Farp2


FERM, RhoGEF and pleckstrin domain protein 2


chr19_-_34877880 3.339 ENSMUST00000112460.1
Pank1
pantothenate kinase 1
chr2_-_160872552 3.224 ENSMUST00000103111.2
Zhx3
zinc fingers and homeoboxes 3
chr7_+_51879041 3.208 ENSMUST00000107591.2
Gas2
growth arrest specific 2
chr18_-_74961252 3.199 ENSMUST00000066532.4
Lipg
lipase, endothelial
chr10_-_109010955 3.160 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr4_-_108118528 3.008 ENSMUST00000030340.8
Scp2
sterol carrier protein 2, liver
chr16_+_38089001 2.973 ENSMUST00000023507.6
Gsk3b
glycogen synthase kinase 3 beta
chr8_-_61591130 2.968 ENSMUST00000135439.1
ENSMUST00000121200.1
Palld

palladin, cytoskeletal associated protein

chr1_-_169747634 2.936 ENSMUST00000027991.5
ENSMUST00000111357.1
Rgs4

regulator of G-protein signaling 4

chr2_-_110305730 2.922 ENSMUST00000046233.2
Bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr12_-_98577940 2.874 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr14_+_55560480 2.858 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11


DDB1 and CUL4 associated factor 11


chr8_-_84893887 2.777 ENSMUST00000003907.7
ENSMUST00000182458.1
ENSMUST00000109745.1
ENSMUST00000142748.1
Gcdh



glutaryl-Coenzyme A dehydrogenase



chr1_+_167598450 2.771 ENSMUST00000111386.1
ENSMUST00000111384.1
Rxrg

retinoid X receptor gamma

chr1_-_9962809 2.744 ENSMUST00000097824.2
Gm10567
predicted gene 10567
chr11_+_112782182 2.708 ENSMUST00000000579.2
Sox9
SRY-box containing gene 9
chr2_+_58754910 2.618 ENSMUST00000059102.6
Upp2
uridine phosphorylase 2
chr19_+_12633507 2.611 ENSMUST00000119960.1
Glyat
glycine-N-acyltransferase
chr7_-_99626936 2.592 ENSMUST00000178124.1
Gm4980
predicted gene 4980
chr13_-_71963713 2.585 ENSMUST00000077337.8
Irx1
Iroquois related homeobox 1 (Drosophila)
chr19_-_32061438 2.549 ENSMUST00000096119.4
Asah2
N-acylsphingosine amidohydrolase 2
chr6_-_89216237 2.524 ENSMUST00000079186.2
Gm839
predicted gene 839
chr1_+_167598384 2.509 ENSMUST00000015987.3
Rxrg
retinoid X receptor gamma
chr17_+_64600702 2.509 ENSMUST00000086723.3
Man2a1
mannosidase 2, alpha 1
chr10_+_127759721 2.486 ENSMUST00000073639.5
Rdh1
retinol dehydrogenase 1 (all trans)
chr2_+_109917639 2.434 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr9_-_50555170 2.420 ENSMUST00000119103.1
Bco2
beta-carotene oxygenase 2
chr12_+_108334341 2.395 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr8_-_93229517 2.383 ENSMUST00000176282.1
ENSMUST00000034173.7
Ces1e

carboxylesterase 1E

chr5_+_43662373 2.308 ENSMUST00000048150.8
Cc2d2a
coiled-coil and C2 domain containing 2A
chr2_-_35100677 2.290 ENSMUST00000045776.4
ENSMUST00000113050.3
AI182371

expressed sequence AI182371

chr7_-_139582790 2.260 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr2_-_58052832 2.212 ENSMUST00000090940.5
Ermn
ermin, ERM-like protein
chr5_+_102768771 2.200 ENSMUST00000112852.1
Arhgap24
Rho GTPase activating protein 24
chr6_+_121300227 2.181 ENSMUST00000064580.7
Slc6a13
solute carrier family 6 (neurotransmitter transporter, GABA), member 13
chr2_+_58755177 2.181 ENSMUST00000102755.3
Upp2
uridine phosphorylase 2
chr3_+_138374121 2.169 ENSMUST00000171054.1
Adh6-ps1
alcohol dehydrogenase 6 (class V), pseudogene 1
chr8_-_91801948 2.125 ENSMUST00000175795.1
Irx3
Iroquois related homeobox 3 (Drosophila)
chr3_+_94372794 2.100 ENSMUST00000029795.3
Rorc
RAR-related orphan receptor gamma
chr11_-_31671727 2.078 ENSMUST00000109415.1
Bod1
biorientation of chromosomes in cell division 1
chr1_-_65179058 2.051 ENSMUST00000097709.4
Idh1
isocitrate dehydrogenase 1 (NADP+), soluble
chrX_-_75875101 2.035 ENSMUST00000114059.3
Pls3
plastin 3 (T-isoform)
chrX_-_8193387 2.034 ENSMUST00000143223.1
ENSMUST00000033509.8
Ebp

phenylalkylamine Ca2+ antagonist (emopamil) binding protein

chr4_+_136143497 2.030 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr5_-_88676135 2.027 ENSMUST00000078945.5
Grsf1
G-rich RNA sequence binding factor 1
chr1_-_140183404 2.006 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr9_-_103219823 1.999 ENSMUST00000168142.1
Trf
transferrin
chr1_-_140183283 1.993 ENSMUST00000111977.1
Cfh
complement component factor h
chr7_-_19796789 1.959 ENSMUST00000108449.2
ENSMUST00000043822.7
Cblc

Casitas B-lineage lymphoma c

chr1_-_168431695 1.945 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chr10_+_34297421 1.936 ENSMUST00000047935.6
Tspyl4
TSPY-like 4
chr17_-_12940317 1.933 ENSMUST00000160378.1
ENSMUST00000043923.5
Acat3

acetyl-Coenzyme A acetyltransferase 3

chr11_-_70514608 1.920 ENSMUST00000021179.3
Vmo1
vitelline membrane outer layer 1 homolog (chicken)
chr7_+_19489045 1.909 ENSMUST00000011407.7
ENSMUST00000137613.1
Exoc3l2

exocyst complex component 3-like 2

chr14_-_36968679 1.897 ENSMUST00000067700.6
Ccser2
coiled-coil serine rich 2
chr1_+_169969409 1.874 ENSMUST00000180638.1
3110045C21Rik
RIKEN cDNA 3110045C21 gene
chr2_-_52335134 1.873 ENSMUST00000075301.3
Neb
nebulin
chr2_-_150451486 1.862 ENSMUST00000109916.1
Zfp442
zinc finger protein 442
chr9_-_21927515 1.823 ENSMUST00000178988.1
ENSMUST00000046831.9
Tmem205

transmembrane protein 205

chr18_-_61536522 1.819 ENSMUST00000171629.1
Arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chr7_+_44590886 1.803 ENSMUST00000107906.3
Kcnc3
potassium voltage gated channel, Shaw-related subfamily, member 3
chr12_-_56613270 1.795 ENSMUST00000072631.5
Nkx2-9
NK2 homeobox 9
chr11_-_86993682 1.793 ENSMUST00000018571.4
Ypel2
yippee-like 2 (Drosophila)
chr13_-_56548534 1.780 ENSMUST00000062806.4
Lect2
leukocyte cell-derived chemotaxin 2
chr14_+_21052574 1.769 ENSMUST00000045376.9
Adk
adenosine kinase
chr9_+_77921908 1.765 ENSMUST00000133757.1
Elovl5
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr6_+_82041623 1.758 ENSMUST00000042974.8
Eva1a
eva-1 homolog A (C. elegans)
chr4_-_41640322 1.757 ENSMUST00000127306.1
Enho
energy homeostasis associated
chr16_+_45093611 1.716 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr8_-_83955205 1.696 ENSMUST00000098595.2
Gm10644
predicted gene 10644
chr8_-_3878549 1.674 ENSMUST00000011445.6
Cd209d
CD209d antigen
chr4_-_104876383 1.668 ENSMUST00000064873.8
ENSMUST00000106808.3
ENSMUST00000048947.8
C8a


complement component 8, alpha polypeptide


chr11_+_117232254 1.665 ENSMUST00000106354.2
Sept9
septin 9
chr15_-_55113460 1.654 ENSMUST00000100659.2
ENSMUST00000110230.1
Gm9920

predicted gene 9920

chr4_-_109156610 1.649 ENSMUST00000161363.1
Osbpl9
oxysterol binding protein-like 9
chr6_+_129180613 1.641 ENSMUST00000032260.5
Clec2d
C-type lectin domain family 2, member d
chr9_+_21927471 1.588 ENSMUST00000170304.1
ENSMUST00000006403.6
Ccdc159

coiled-coil domain containing 159

chr9_+_70207342 1.585 ENSMUST00000034745.7
Myo1e
myosin IE
chr17_-_47421873 1.522 ENSMUST00000073143.6
1700001C19Rik
RIKEN cDNA 1700001C19 gene
chr14_-_61556746 1.521 ENSMUST00000100496.4
Spryd7
SPRY domain containing 7
chr6_-_23132981 1.518 ENSMUST00000031707.7
Aass
aminoadipate-semialdehyde synthase
chr7_-_25539845 1.512 ENSMUST00000066503.7
ENSMUST00000064862.6
Ceacam2

carcinoembryonic antigen-related cell adhesion molecule 2

chr13_+_4049001 1.490 ENSMUST00000118717.2
Akr1c14
aldo-keto reductase family 1, member C14
chr6_-_72362382 1.472 ENSMUST00000114095.1
ENSMUST00000069595.6
ENSMUST00000069580.5
Rnf181


ring finger protein 181


chr4_+_89137122 1.448 ENSMUST00000058030.7
Mtap
methylthioadenosine phosphorylase
chr7_-_137410717 1.446 ENSMUST00000120340.1
ENSMUST00000117404.1
ENSMUST00000068996.6
9430038I01Rik


RIKEN cDNA 9430038I01 gene


chr4_+_97777780 1.446 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr10_-_54075730 1.442 ENSMUST00000105469.1
ENSMUST00000003843.8
Man1a

mannosidase 1, alpha

chr11_+_83709015 1.440 ENSMUST00000001009.7
Wfdc18
WAP four-disulfide core domain 18
chr13_+_63015167 1.432 ENSMUST00000021911.8
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chrX_-_147429189 1.418 ENSMUST00000033646.2
Il13ra2
interleukin 13 receptor, alpha 2
chr2_-_104742802 1.416 ENSMUST00000028595.7
Depdc7
DEP domain containing 7
chr4_+_135946447 1.416 ENSMUST00000030432.7
Hmgcl
3-hydroxy-3-methylglutaryl-Coenzyme A lyase
chr14_+_55559993 1.409 ENSMUST00000117236.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr4_+_43046014 1.397 ENSMUST00000180426.1
Gm26881
predicted gene, 26881
chr14_+_123659971 1.390 ENSMUST00000049681.7
Itgbl1
integrin, beta-like 1
chr17_-_46032366 1.388 ENSMUST00000071648.5
ENSMUST00000142351.2
ENSMUST00000167860.1
Vegfa


vascular endothelial growth factor A


chr14_-_55560340 1.387 ENSMUST00000066106.3
A730061H03Rik
RIKEN cDNA A730061H03 gene
chr8_-_77610597 1.380 ENSMUST00000034030.8
Tmem184c
transmembrane protein 184C
chr1_-_169969143 1.376 ENSMUST00000027989.6
ENSMUST00000111353.3
Hsd17b7

hydroxysteroid (17-beta) dehydrogenase 7

chr7_+_101378183 1.372 ENSMUST00000084895.5
Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr17_-_36058371 1.367 ENSMUST00000113742.2
Gm11127
predicted gene 11127
chr13_-_62888282 1.364 ENSMUST00000092888.4
Fbp1
fructose bisphosphatase 1
chr1_+_152399824 1.363 ENSMUST00000044311.8
Colgalt2
collagen beta(1-O)galactosyltransferase 2
chr13_+_55714624 1.360 ENSMUST00000021959.9
Txndc15
thioredoxin domain containing 15
chr19_+_46623387 1.350 ENSMUST00000111855.4
Wbp1l
WW domain binding protein 1 like
chrX_+_38600626 1.343 ENSMUST00000000365.2
Mcts1
malignant T cell amplified sequence 1
chr10_+_94036001 1.341 ENSMUST00000020208.4
Fgd6
FYVE, RhoGEF and PH domain containing 6
chrX_+_142226765 1.338 ENSMUST00000112916.2
Nxt2
nuclear transport factor 2-like export factor 2
chr14_+_12189943 1.331 ENSMUST00000119888.1
Ptprg
protein tyrosine phosphatase, receptor type, G
chrX_+_103356464 1.328 ENSMUST00000116547.2
Chic1
cysteine-rich hydrophobic domain 1
chr2_+_127270208 1.327 ENSMUST00000110375.2
Stard7
START domain containing 7
chr8_+_45627709 1.325 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr7_-_45103747 1.321 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chrX_+_129749740 1.320 ENSMUST00000167619.2
ENSMUST00000037854.8
Diap2

diaphanous homolog 2 (Drosophila)

chr14_+_55560010 1.317 ENSMUST00000147981.1
ENSMUST00000133256.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr4_+_116596672 1.317 ENSMUST00000051869.7
Ccdc17
coiled-coil domain containing 17
chr19_+_26749726 1.313 ENSMUST00000175842.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_19957037 1.306 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr13_+_42301270 1.304 ENSMUST00000021796.7
Edn1
endothelin 1
chr7_-_5805445 1.299 ENSMUST00000075085.6
Vmn1r63
vomeronasal 1 receptor 63
chr8_-_77610668 1.294 ENSMUST00000141202.1
ENSMUST00000152168.1
Tmem184c

transmembrane protein 184C

chr4_+_43406435 1.293 ENSMUST00000098106.2
ENSMUST00000139198.1
Rusc2

RUN and SH3 domain containing 2

chr4_+_150855064 1.291 ENSMUST00000030811.1
Errfi1
ERBB receptor feedback inhibitor 1
chr17_-_34959232 1.289 ENSMUST00000165202.1
ENSMUST00000172753.1
Hspa1b

heat shock protein 1B

chrX_+_129749830 1.281 ENSMUST00000113320.2
Diap2
diaphanous homolog 2 (Drosophila)
chr15_+_99295087 1.274 ENSMUST00000128352.1
ENSMUST00000145482.1
Prpf40b

PRP40 pre-mRNA processing factor 40 homolog B (yeast)

chr11_-_11898044 1.271 ENSMUST00000066237.3
Ddc
dopa decarboxylase
chr9_+_20581296 1.263 ENSMUST00000115557.2
Zfp846
zinc finger protein 846
chr16_+_45094036 1.259 ENSMUST00000061050.5
Ccdc80
coiled-coil domain containing 80
chr4_-_154899077 1.257 ENSMUST00000030935.3
ENSMUST00000132281.1
Fam213b

family with sequence similarity 213, member B

chr9_+_44084944 1.250 ENSMUST00000176416.1
ENSMUST00000065461.7
Usp2

ubiquitin specific peptidase 2

chr11_+_94328242 1.236 ENSMUST00000021227.5
Ankrd40
ankyrin repeat domain 40
chr8_-_41215146 1.231 ENSMUST00000034003.4
Fgl1
fibrinogen-like protein 1
chr10_+_18469958 1.228 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chr7_+_66079643 1.225 ENSMUST00000101801.5
Vimp
VCP-interacting membrane protein
chr8_-_72435043 1.224 ENSMUST00000109974.1
Calr3
calreticulin 3
chr4_-_6275629 1.222 ENSMUST00000029905.1
Cyp7a1
cytochrome P450, family 7, subfamily a, polypeptide 1
chr11_-_11898092 1.219 ENSMUST00000178704.1
Ddc
dopa decarboxylase
chr2_+_177897096 1.218 ENSMUST00000108935.1
Gm14327
predicted gene 14327
chr14_-_72602945 1.214 ENSMUST00000162825.1
Fndc3a
fibronectin type III domain containing 3A
chr1_+_185332143 1.213 ENSMUST00000027916.6
ENSMUST00000151769.1
ENSMUST00000110965.1
Bpnt1


bisphosphate 3'-nucleotidase 1


chr11_+_87592145 1.211 ENSMUST00000103179.3
ENSMUST00000092802.5
ENSMUST00000146871.1
Mtmr4


myotubularin related protein 4


chr1_+_21240581 1.210 ENSMUST00000027067.8
Gsta3
glutathione S-transferase, alpha 3
chr1_+_21240597 1.203 ENSMUST00000121676.1
Gsta3
glutathione S-transferase, alpha 3
chr17_-_46890405 1.203 ENSMUST00000086675.3
A330017A19Rik
RIKEN cDNA A330017A19 gene
chr17_+_36121666 1.199 ENSMUST00000173128.1
Gm19684
predicted gene, 19684
chr7_-_80405425 1.185 ENSMUST00000107362.3
ENSMUST00000135306.1
Furin

furin (paired basic amino acid cleaving enzyme)

chr10_-_89506631 1.181 ENSMUST00000058126.8
ENSMUST00000105296.2
Nr1h4

nuclear receptor subfamily 1, group H, member 4

chr5_-_137684665 1.175 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
Agfg2


ArfGAP with FG repeats 2


chr8_-_3748941 1.174 ENSMUST00000012847.1
Cd209a
CD209a antigen
chr3_-_107943705 1.172 ENSMUST00000106680.1
ENSMUST00000106684.1
ENSMUST00000106685.2
Gstm6


glutathione S-transferase, mu 6


chr17_-_91092715 1.152 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
Nrxn1


neurexin I


chr13_+_16011851 1.150 ENSMUST00000042603.6
Inhba
inhibin beta-A
chr10_-_75780954 1.148 ENSMUST00000173537.1
ENSMUST00000173512.1
Gstt3
Gm20441
glutathione S-transferase, theta 3
predicted gene 20441
chr2_+_143915273 1.146 ENSMUST00000103172.3
Dstn
destrin
chr13_+_9276477 1.145 ENSMUST00000174552.1
Dip2c
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr7_-_140116395 1.139 ENSMUST00000026538.6
Echs1
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial
chr1_+_88138364 1.136 ENSMUST00000014263.4
Ugt1a6a
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr7_-_25754701 1.132 ENSMUST00000108401.1
ENSMUST00000043765.7
Hnrnpul1

heterogeneous nuclear ribonucleoprotein U-like 1

chr2_-_64975762 1.127 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr4_+_97777606 1.126 ENSMUST00000075448.6
ENSMUST00000092532.6
Nfia

nuclear factor I/A

chr11_+_70540064 1.126 ENSMUST00000157075.1
Pld2
phospholipase D2
chr11_+_95842283 1.123 ENSMUST00000107714.2
ENSMUST00000107711.1
Gngt2

guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2

chr3_-_97297778 1.123 ENSMUST00000181368.1
Gm17608
predicted gene, 17608
chr11_+_71019593 1.116 ENSMUST00000133413.1
ENSMUST00000164220.1
ENSMUST00000048807.5
Mis12


MIS12 homolog (yeast)


chr11_-_115187827 1.108 ENSMUST00000103041.1
Nat9
N-acetyltransferase 9 (GCN5-related, putative)
chr3_-_148989316 1.100 ENSMUST00000098518.2
Lphn2
latrophilin 2
chr7_+_4237699 1.099 ENSMUST00000117550.1
Lilra5
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr5_-_66151903 1.093 ENSMUST00000167950.1
Rbm47
RNA binding motif protein 47
chr2_-_26092149 1.093 ENSMUST00000114159.2
Nacc2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr7_-_101933815 1.089 ENSMUST00000106963.1
ENSMUST00000106966.1
Lrrc51

leucine rich repeat containing 51

chr19_+_11912389 1.087 ENSMUST00000061618.7
Patl1
protein associated with topoisomerase II homolog 1 (yeast)
chr14_-_45530118 1.081 ENSMUST00000045905.6
Fermt2
fermitin family homolog 2 (Drosophila)
chr6_-_87851011 1.081 ENSMUST00000113617.1
Cnbp
cellular nucleic acid binding protein
chr11_-_23770953 1.081 ENSMUST00000102864.3
Rel
reticuloendotheliosis oncogene
chr19_+_44989073 1.074 ENSMUST00000026225.8
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.6 GO:1901373 lipid hydroperoxide transport(GO:1901373)
1.5 4.6 GO:0070947 neutrophil mediated killing of fungus(GO:0070947) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
1.0 3.0 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
1.0 4.0 GO:0006069 ethanol oxidation(GO:0006069)
0.9 2.7 GO:0035622 intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034)
0.8 2.4 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.8 2.4 GO:0043387 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377)
0.8 3.2 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.8 3.2 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.8 12.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.7 2.9 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.7 2.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.7 4.7 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.6 3.9 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.6 1.9 GO:0038189 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190)
0.6 3.8 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.5 1.5 GO:0006553 lysine metabolic process(GO:0006553)
0.5 1.5 GO:0070347 brown fat cell proliferation(GO:0070342) regulation of brown fat cell proliferation(GO:0070347)
0.4 1.2 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.4 1.5 GO:0002188 translation reinitiation(GO:0002188)
0.4 1.1 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.4 0.7 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.4 1.1 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.4 2.5 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.4 1.4 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.3 1.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.3 1.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.3 1.4 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.3 0.3 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.3 2.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.3 2.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3 2.3 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.3 4.5 GO:0036315 cellular response to sterol(GO:0036315)
0.3 1.6 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.3 5.8 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.3 1.2 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.3 1.2 GO:0090472 dibasic protein processing(GO:0090472)
0.3 1.2 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.3 3.2 GO:0005513 detection of calcium ion(GO:0005513)
0.3 1.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.3 2.0 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.3 2.5 GO:0006013 mannose metabolic process(GO:0006013)
0.3 1.3 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.3 9.9 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.3 2.8 GO:0035337 fatty-acyl-CoA metabolic process(GO:0035337)
0.2 1.0 GO:0097168 condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168)
0.2 2.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 3.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 1.6 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.2 0.7 GO:2001228 regulation of response to gamma radiation(GO:2001228)
0.2 3.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 0.7 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.2 0.9 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.2 1.5 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.2 0.6 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.2 0.6 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.2 0.6 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.2 2.6 GO:0072189 ureter development(GO:0072189)
0.2 3.4 GO:0016322 neuron remodeling(GO:0016322)
0.2 2.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 1.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 0.9 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.2 0.6 GO:0009106 lipoate metabolic process(GO:0009106)
0.2 0.7 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.2 1.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.2 0.6 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.2 0.2 GO:2000137 negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137)
0.2 0.7 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.2 1.6 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.2 1.4 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.2 0.7 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.2 1.7 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 0.8 GO:0061744 motor behavior(GO:0061744)
0.2 1.9 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.2 1.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2 2.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.4 GO:0070268 cornification(GO:0070268)
0.1 1.8 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.3 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.3 GO:0031179 peptide modification(GO:0031179)
0.1 0.4 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 1.0 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 3.0 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.7 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 0.8 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 4.1 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.1 0.8 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.9 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.7 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.1 1.3 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.1 0.7 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 1.9 GO:0051601 exocyst localization(GO:0051601)
0.1 0.7 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1 0.9 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 1.0 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.4 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 3.1 GO:0035634 response to stilbenoid(GO:0035634)
0.1 0.3 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.5 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.4 GO:0046210 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.1 0.4 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 1.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 1.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 2.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 1.1 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.3 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.4 GO:0061296 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.1 5.0 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 2.0 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.4 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 2.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 0.4 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 2.5 GO:0001523 retinoid metabolic process(GO:0001523)
0.1 0.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 1.4 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.0 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 2.0 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.1 0.7 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 0.3 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.6 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.1 1.0 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.1 GO:0021859 pyramidal neuron differentiation(GO:0021859)
0.1 0.2 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.1 0.9 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.3 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 0.3 GO:0051661 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.1 1.3 GO:0051028 mRNA transport(GO:0051028)
0.1 0.5 GO:0007343 egg activation(GO:0007343)
0.1 0.8 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 2.9 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 1.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.8 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.5 GO:0030242 autophagy of peroxisome(GO:0030242) peroxisome disassembly(GO:1905683)
0.1 1.0 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.9 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 1.3 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 1.7 GO:1902857 positive regulation of non-motile cilium assembly(GO:1902857)
0.1 0.8 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 0.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.7 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.4 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.1 0.9 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.6 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.1 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 1.0 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.1 0.2 GO:0043519 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.1 1.2 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.1 3.9 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 0.2 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.1 0.7 GO:0006105 succinate metabolic process(GO:0006105)
0.1 0.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 10.3 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.3 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.0 1.8 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.5 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.3 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 1.3 GO:0046688 response to copper ion(GO:0046688)
0.0 0.6 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.7 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.4 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.7 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.3 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 2.3 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.5 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.1 GO:0070973 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.0 3.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.2 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 1.1 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.8 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.2 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.9 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 2.5 GO:0009166 nucleotide catabolic process(GO:0009166)
0.0 1.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.1 GO:2000412 tolerance induction to self antigen(GO:0002513) positive regulation of thymocyte migration(GO:2000412)
0.0 0.5 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 1.4 GO:0043171 peptide catabolic process(GO:0043171)
0.0 2.0 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.0 GO:0046544 follicle-stimulating hormone signaling pathway(GO:0042699) development of secondary male sexual characteristics(GO:0046544)
0.0 0.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 9.1 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.1 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.0 1.8 GO:0001656 metanephros development(GO:0001656)
0.0 1.9 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.2 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 1.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.7 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.4 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 1.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.6 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 1.6 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.5 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.6 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 2.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 1.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.0 GO:0033577 protein glycosylation in endoplasmic reticulum(GO:0033577)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.0 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.0 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 1.9 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.5 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.8 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.8 GO:0007032 endosome organization(GO:0007032)
0.0 0.2 GO:0046549 amacrine cell differentiation(GO:0035881) retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 1.2 GO:0030193 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 0.4 GO:0071353 response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
0.0 2.8 GO:0016042 lipid catabolic process(GO:0016042)
0.0 0.4 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 2.6 GO:0006665 sphingolipid metabolic process(GO:0006665)
0.0 0.6 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.4 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.4 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 1.2 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.8 GO:1901998 toxin transport(GO:1901998)
0.0 0.8 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.0 GO:0042414 epinephrine metabolic process(GO:0042414) response to norepinephrine(GO:0071873)
0.0 1.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.8 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.7 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.3 GO:0007617 mating behavior(GO:0007617)
0.0 0.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.4 GO:0060964 regulation of gene silencing by miRNA(GO:0060964)
0.0 0.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.5 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.6 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.4 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.5 4.1 GO:0045098 type III intermediate filament(GO:0045098)
0.5 1.9 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.4 1.8 GO:0097447 dendritic tree(GO:0097447)
0.4 1.1 GO:0043512 inhibin A complex(GO:0043512)
0.3 3.2 GO:0005579 membrane attack complex(GO:0005579)
0.3 1.9 GO:0032437 cuticular plate(GO:0032437)
0.3 4.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.3 11.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.3 2.2 GO:0033269 internode region of axon(GO:0033269)
0.3 1.0 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 3.0 GO:1990909 Wnt signalosome(GO:1990909)
0.2 2.2 GO:0097433 dense body(GO:0097433)
0.2 1.9 GO:0030478 actin cap(GO:0030478)
0.2 0.6 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.2 0.4 GO:0030125 clathrin vesicle coat(GO:0030125)
0.2 0.9 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.2 0.6 GO:0043159 acrosomal matrix(GO:0043159)
0.2 0.9 GO:0002079 inner acrosomal membrane(GO:0002079)
0.2 0.7 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 3.2 GO:0031045 dense core granule(GO:0031045)
0.2 1.3 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 0.5 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.6 GO:0071953 elastic fiber(GO:0071953)
0.1 0.6 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 4.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 1.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 2.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 0.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.3 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.1 1.8 GO:0036038 MKS complex(GO:0036038)
0.1 0.8 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 2.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 3.0 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.8 GO:0005787 signal peptidase complex(GO:0005787)
0.1 1.7 GO:0031105 septin complex(GO:0031105)
0.1 0.3 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.1 0.7 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 1.6 GO:0045180 basal cortex(GO:0045180)
0.1 0.6 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.7 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 1.9 GO:0000145 exocyst(GO:0000145)
0.1 3.5 GO:0030118 clathrin coat(GO:0030118)
0.1 1.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 1.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 1.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 3.0 GO:0002102 podosome(GO:0002102)
0.1 1.0 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.6 GO:0042587 glycogen granule(GO:0042587)
0.1 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.5 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.7 GO:0031209 SCAR complex(GO:0031209)
0.1 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 1.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 2.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.8 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 1.5 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 6.8 GO:0072562 blood microparticle(GO:0072562)
0.0 2.0 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.7 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 1.0 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.4 GO:0032994 protein-lipid complex(GO:0032994)
0.0 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0033391 chromatoid body(GO:0033391)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 1.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834) GTPase complex(GO:1905360)
0.0 5.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.5 GO:0032421 stereocilium(GO:0032420) stereocilium bundle(GO:0032421)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 2.9 GO:0042641 actomyosin(GO:0042641)
0.0 3.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.7 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 2.5 GO:0005769 early endosome(GO:0005769)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 6.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.8 GO:0031201 SNARE complex(GO:0031201)
0.0 3.8 GO:0005938 cell cortex(GO:0005938)
0.0 0.1 GO:0106003 amyloid-beta complex(GO:0106003)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 2.2 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.8 GO:0042629 mast cell granule(GO:0042629)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.0 2.0 GO:0005770 late endosome(GO:0005770)
0.0 2.0 GO:0043209 myelin sheath(GO:0043209)
0.0 0.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 2.7 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 2.0 GO:0004769 steroid delta-isomerase activity(GO:0004769)
1.7 6.6 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632)
1.3 4.0 GO:0003960 NADPH:quinone reductase activity(GO:0003960) alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.3 3.8 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
1.1 3.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
1.0 9.8 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
1.0 4.8 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.8 3.3 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.8 3.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.7 2.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.7 3.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.6 1.9 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.6 4.0 GO:0001851 complement component C3b binding(GO:0001851)
0.5 7.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.5 3.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.5 1.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.5 1.4 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.5 1.4 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.4 2.5 GO:0017040 ceramidase activity(GO:0017040)
0.4 2.1 GO:0008142 oxysterol binding(GO:0008142)
0.4 2.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.4 4.0 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.4 2.5 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.4 4.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.4 1.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.3 1.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 1.9 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.3 1.2 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.3 5.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.3 0.9 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.3 2.0 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.3 1.3 GO:0019770 IgG receptor activity(GO:0019770)
0.3 2.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2 0.7 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 1.5 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.2 1.2 GO:0038181 bile acid receptor activity(GO:0038181)
0.2 8.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 1.6 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.2 0.7 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.2 0.8 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.2 6.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.2 0.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 1.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 2.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 0.5 GO:0004771 sterol esterase activity(GO:0004771)
0.2 0.7 GO:0036033 mediator complex binding(GO:0036033)
0.2 1.7 GO:0004462 hydroxyacylglutathione hydrolase activity(GO:0004416) lactoylglutathione lyase activity(GO:0004462)
0.2 1.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 0.8 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.2 2.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 1.8 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.6 GO:0070573 tripeptidyl-peptidase activity(GO:0008240) bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
0.1 0.7 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 2.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 1.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.8 GO:0019206 nucleoside kinase activity(GO:0019206)
0.1 1.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 1.6 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.1 0.8 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 1.1 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.4 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 2.6 GO:0005537 mannose binding(GO:0005537)
0.1 2.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 1.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.4 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.1 1.0 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 5.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 4.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 3.9 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 12.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 3.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.7 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.2 GO:0031386 protein tag(GO:0031386)
0.1 1.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.6 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.6 GO:0043199 sulfate binding(GO:0043199)
0.1 0.5 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 1.5 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 1.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.3 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.9 GO:0042605 peptide antigen binding(GO:0042605)
0.1 1.8 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.4 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 3.4 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.3 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 2.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 3.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.4 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 1.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.9 GO:0001540 amyloid-beta binding(GO:0001540)
0.0 1.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 1.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.7 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 6.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 2.1 GO:0005179 hormone activity(GO:0005179)
0.0 1.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.5 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.3 GO:0001972 retinoic acid binding(GO:0001972)
0.0 2.1 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 1.1 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 1.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.9 GO:0017022 myosin binding(GO:0017022)
0.0 0.6 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 2.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0003690 double-stranded DNA binding(GO:0003690)
0.0 0.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.8 GO:0015645 fatty acid ligase activity(GO:0015645)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 2.9 GO:0008017 microtubule binding(GO:0008017)
0.0 3.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.2 10.9 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.6 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 4.1 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.1 0.8 SIG_CHEMOTAXIS Genes related to chemotaxis
0.1 5.3 PID_IL23_PATHWAY IL23-mediated signaling events
0.1 3.0 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 2.3 PID_ARF_3PATHWAY Arf1 pathway
0.1 5.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 4.9 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.9 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.0 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.7 PID_ALK1_PATHWAY ALK1 signaling events
0.1 1.6 PID_CONE_PATHWAY Visual signal transduction: Cones
0.1 0.7 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.7 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 3.9 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.1 1.1 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.1 0.6 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 0.5 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 1.6 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 1.0 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 1.1 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.8 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.7 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 1.4 PID_ARF6_PATHWAY Arf6 signaling events
0.0 2.4 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 0.8 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 5.2 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 1.0 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 1.2 PID_P73PATHWAY p73 transcription factor network
0.0 0.2 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.7 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.6 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.7 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 0.3 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.0 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.7 5.9 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.5 2.0 REACTOME_INFLUENZA_LIFE_CYCLE Genes involved in Influenza Life Cycle
0.4 14.1 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.4 10.9 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS Genes involved in Synthesis of bile acids and bile salts
0.3 4.8 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.3 3.2 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 2.9 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 3.3 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 3.4 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 6.0 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 0.7 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.6 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.5 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 12.9 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.4 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.3 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 2.1 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 3.9 REACTOME_CTLA4_INHIBITORY_SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 1.8 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 1.2 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.8 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 2.3 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.2 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.4 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 3.8 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 0.2 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 1.6 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 5.0 REACTOME_PHASE_II_CONJUGATION Genes involved in Phase II conjugation
0.1 1.2 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 3.5 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.1 1.1 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 5.1 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.1 1.5 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.1 2.5 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 0.6 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.0 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 0.7 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 1.4 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 1.9 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.1 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.9 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.1 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 6.5 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.7 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.0 0.6 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 1.4 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.6 REACTOME_SPHINGOLIPID_METABOLISM Genes involved in Sphingolipid metabolism
0.0 1.3 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 0.8 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.7 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.0 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.3 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.6 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.4 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.8 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis