Motif ID: Gli3_Zic1

Z-value: 1.521

Transcription factors associated with Gli3_Zic1:

Gene SymbolEntrez IDGene Name
Gli3 ENSMUSG00000021318.9 Gli3
Zic1 ENSMUSG00000032368.8 Zic1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gli3mm10_v2_chr13_+_15463837_154639800.812.0e-09Click!
Zic1mm10_v2_chr9_-_91365778_913658150.492.5e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gli3_Zic1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_142657466 14.081 ENSMUST00000097936.2
ENSMUST00000000033.5
Igf2

insulin-like growth factor 2

chr12_+_109453455 12.874 ENSMUST00000109844.4
ENSMUST00000109842.2
ENSMUST00000109843.1
ENSMUST00000109846.4
ENSMUST00000173539.1
ENSMUST00000109841.2
Dlk1





delta-like 1 homolog (Drosophila)





chr11_+_72999069 11.197 ENSMUST00000021141.7
P2rx1
purinergic receptor P2X, ligand-gated ion channel, 1
chr7_+_24370255 11.111 ENSMUST00000171904.1
Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr6_+_30738044 9.343 ENSMUST00000128398.1
ENSMUST00000163949.2
ENSMUST00000124665.1
Mest


mesoderm specific transcript


chr11_-_102365111 9.104 ENSMUST00000006749.9
Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr2_+_157560078 9.027 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
Nnat







neuronatin







chr6_+_113531675 8.812 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr9_-_103480328 7.534 ENSMUST00000124310.2
Bfsp2
beaded filament structural protein 2, phakinin
chr12_+_109540979 7.403 ENSMUST00000129245.1
ENSMUST00000143836.1
ENSMUST00000124106.1
Meg3


maternally expressed 3


chr7_-_142656018 6.937 ENSMUST00000178921.1
Igf2
insulin-like growth factor 2
chr12_+_109545390 6.653 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr13_+_44729535 6.426 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr18_-_78142119 5.802 ENSMUST00000160639.1
Slc14a1
solute carrier family 14 (urea transporter), member 1
chr7_-_24760311 5.469 ENSMUST00000063956.5
Cd177
CD177 antigen
chr8_+_23139064 5.412 ENSMUST00000033947.8
Ank1
ankyrin 1, erythroid
chr4_-_68954351 5.320 ENSMUST00000030036.5
Brinp1
bone morphogenic protein/retinoic acid inducible neural specific 1
chr11_+_11684967 5.036 ENSMUST00000126058.1
ENSMUST00000141436.1
Ikzf1

IKAROS family zinc finger 1

chr8_+_23139030 4.942 ENSMUST00000121075.1
Ank1
ankyrin 1, erythroid
chr10_-_127341583 4.417 ENSMUST00000026474.3
Gli1
GLI-Kruppel family member GLI1
chrX_-_7574120 4.220 ENSMUST00000045924.7
ENSMUST00000115742.2
ENSMUST00000150787.1
Ppp1r3f


protein phosphatase 1, regulatory (inhibitor) subunit 3F


chr11_+_101176041 4.050 ENSMUST00000103109.3
Cntnap1
contactin associated protein-like 1
chr1_-_133801031 4.050 ENSMUST00000143567.1
Atp2b4
ATPase, Ca++ transporting, plasma membrane 4
chr4_-_148130678 3.842 ENSMUST00000030862.4
Draxin
dorsal inhibitory axon guidance protein
chr7_+_99268338 3.680 ENSMUST00000107100.2
Map6
microtubule-associated protein 6
chr11_+_72042455 3.669 ENSMUST00000021164.3
Fam64a
family with sequence similarity 64, member A
chr13_-_117025505 3.665 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr17_+_25366550 3.658 ENSMUST00000069616.7
Tpsb2
tryptase beta 2
chr18_-_35662180 3.647 ENSMUST00000025209.4
ENSMUST00000096573.2
Spata24

spermatogenesis associated 24

chr10_-_79788924 3.619 ENSMUST00000020573.6
Prss57
protease, serine 57
chr15_-_103310425 3.614 ENSMUST00000079824.4
Gpr84
G protein-coupled receptor 84
chr15_-_100669496 3.557 ENSMUST00000182814.1
ENSMUST00000182068.1
Bin2

bridging integrator 2

chr2_-_150668198 3.542 ENSMUST00000028944.3
Acss1
acyl-CoA synthetase short-chain family member 1
chr15_-_100669512 3.515 ENSMUST00000182574.1
ENSMUST00000182775.1
Bin2

bridging integrator 2

chr4_-_83021102 3.458 ENSMUST00000071708.5
Frem1
Fras1 related extracellular matrix protein 1
chrX_-_7964166 3.435 ENSMUST00000128449.1
Gata1
GATA binding protein 1
chr8_-_71723308 3.424 ENSMUST00000125092.1
Fcho1
FCH domain only 1
chr7_+_27499315 3.401 ENSMUST00000098644.2
ENSMUST00000108355.1
Prx

periaxin

chr3_-_69044697 3.338 ENSMUST00000136512.1
ENSMUST00000143454.1
ENSMUST00000107802.1
Trim59


tripartite motif-containing 59


chr15_+_102296256 3.291 ENSMUST00000064924.4
Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr13_+_108316395 3.213 ENSMUST00000171178.1
Depdc1b
DEP domain containing 1B
chr9_+_62858085 3.198 ENSMUST00000034777.6
ENSMUST00000163820.1
Calml4

calmodulin-like 4

chr2_+_35282380 3.075 ENSMUST00000028239.6
Gsn
gelsolin
chrX_+_159303266 3.034 ENSMUST00000112491.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr2_+_118111876 3.020 ENSMUST00000039559.8
Thbs1
thrombospondin 1
chr7_+_28540863 2.959 ENSMUST00000119180.2
Sycn
syncollin
chr15_+_99074968 2.954 ENSMUST00000039665.6
Troap
trophinin associated protein
chr4_-_4138432 2.896 ENSMUST00000070375.7
Penk
preproenkephalin
chr5_+_5573952 2.862 ENSMUST00000101627.2
Gm8773
predicted gene 8773
chr9_-_123678782 2.860 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chrX_-_150812715 2.851 ENSMUST00000112697.3
Maged2
melanoma antigen, family D, 2
chr9_-_123678873 2.752 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr7_+_5056856 2.726 ENSMUST00000131368.1
ENSMUST00000123956.1
Ccdc106

coiled-coil domain containing 106

chr15_-_95528702 2.642 ENSMUST00000166170.1
Nell2
NEL-like 2
chr15_-_85581809 2.629 ENSMUST00000023015.7
Wnt7b
wingless-related MMTV integration site 7B
chr1_-_75505641 2.628 ENSMUST00000155084.1
Obsl1
obscurin-like 1
chr17_+_56304313 2.626 ENSMUST00000113035.1
ENSMUST00000113039.2
ENSMUST00000142387.1
Uhrf1


ubiquitin-like, containing PHD and RING finger domains, 1


chr11_+_69095217 2.503 ENSMUST00000101004.2
Per1
period circadian clock 1
chr2_-_156839790 2.478 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
Gm14230


predicted gene 14230


chr4_-_117178726 2.476 ENSMUST00000153953.1
ENSMUST00000106436.1
Kif2c

kinesin family member 2C

chr11_-_83462961 2.472 ENSMUST00000021020.6
ENSMUST00000119346.1
ENSMUST00000103209.3
ENSMUST00000108137.2
Mmp28



matrix metallopeptidase 28 (epilysin)



chr4_+_44943727 2.445 ENSMUST00000154177.1
Gm12678
predicted gene 12678
chr5_-_24730635 2.432 ENSMUST00000068693.5
Wdr86
WD repeat domain 86
chr1_+_129273344 2.405 ENSMUST00000073527.6
ENSMUST00000040311.7
Thsd7b

thrombospondin, type I, domain containing 7B

chr9_-_35558522 2.363 ENSMUST00000034612.5
Ddx25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr4_+_43957401 2.353 ENSMUST00000030202.7
Glipr2
GLI pathogenesis-related 2
chr9_-_108190352 2.328 ENSMUST00000035208.7
Bsn
bassoon
chr7_-_126704816 2.307 ENSMUST00000032949.7
Coro1a
coronin, actin binding protein 1A
chr2_-_91931675 2.304 ENSMUST00000111309.1
Mdk
midkine
chr8_+_123411424 2.264 ENSMUST00000071134.3
Tubb3
tubulin, beta 3 class III
chr1_-_75506331 2.228 ENSMUST00000113567.2
ENSMUST00000113565.2
Obsl1

obscurin-like 1

chr7_-_44227421 2.203 ENSMUST00000072123.4
Gm10109
predicted gene 10109
chr2_-_92371039 2.186 ENSMUST00000068586.6
Gyltl1b
glycosyltransferase-like 1B
chr10_+_79777261 2.178 ENSMUST00000020575.4
Fstl3
follistatin-like 3
chr11_+_75656103 2.163 ENSMUST00000136935.1
Myo1c
myosin IC
chr11_+_96282648 2.158 ENSMUST00000168043.1
Hoxb8
homeobox B8
chr8_-_105637403 2.157 ENSMUST00000182046.1
Gm5914
predicted gene 5914
chr12_+_103388656 2.148 ENSMUST00000101094.2
ENSMUST00000021620.6
Otub2

OTU domain, ubiquitin aldehyde binding 2

chr13_-_99516537 2.146 ENSMUST00000064762.4
Map1b
microtubule-associated protein 1B
chr3_+_31149934 2.129 ENSMUST00000046174.6
Cldn11
claudin 11
chrX_+_74329058 2.117 ENSMUST00000004326.3
Plxna3
plexin A3
chr11_-_78245942 2.076 ENSMUST00000002121.4
Supt6
suppressor of Ty 6
chr7_-_126704736 2.063 ENSMUST00000131415.1
Coro1a
coronin, actin binding protein 1A
chr17_-_25727364 2.014 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr7_+_27258725 2.013 ENSMUST00000079258.6
Numbl
numb-like
chr12_-_32953772 1.989 ENSMUST00000180391.1
ENSMUST00000181670.1
4933406C10Rik

RIKEN cDNA 4933406C10 gene

chr11_+_70000578 1.949 ENSMUST00000019362.8
Dvl2
dishevelled 2, dsh homolog (Drosophila)
chr11_+_100415722 1.938 ENSMUST00000107400.2
Fkbp10
FK506 binding protein 10
chrX_-_150812932 1.926 ENSMUST00000131241.1
ENSMUST00000147152.1
ENSMUST00000143843.1
Maged2


melanoma antigen, family D, 2


chr7_-_118443549 1.912 ENSMUST00000081574.4
Syt17
synaptotagmin XVII
chr5_-_117319242 1.912 ENSMUST00000100834.1
Gm10399
predicted gene 10399
chr7_+_5056706 1.901 ENSMUST00000144802.1
Ccdc106
coiled-coil domain containing 106
chr2_+_29889720 1.855 ENSMUST00000113767.1
Odf2
outer dense fiber of sperm tails 2
chr18_-_21652362 1.824 ENSMUST00000049105.4
Klhl14
kelch-like 14
chr6_-_125494754 1.804 ENSMUST00000032492.8
Cd9
CD9 antigen
chr15_+_78899755 1.803 ENSMUST00000001226.3
ENSMUST00000061239.7
ENSMUST00000109698.2
Sh3bp1


SH3-domain binding protein 1


chr8_+_68880491 1.794 ENSMUST00000015712.8
Lpl
lipoprotein lipase
chr11_+_115154139 1.794 ENSMUST00000021076.5
Rab37
RAB37, member of RAS oncogene family
chr15_-_95528228 1.784 ENSMUST00000075275.2
Nell2
NEL-like 2
chr6_-_118780324 1.763 ENSMUST00000112793.3
ENSMUST00000075591.6
ENSMUST00000078320.7
ENSMUST00000112790.2
Cacna1c



calcium channel, voltage-dependent, L type, alpha 1C subunit



chr4_+_43957678 1.762 ENSMUST00000107855.1
Glipr2
GLI pathogenesis-related 2
chr8_+_70501116 1.761 ENSMUST00000127983.1
Crlf1
cytokine receptor-like factor 1
chr3_+_105904377 1.712 ENSMUST00000000574.1
Adora3
adenosine A3 receptor
chr2_+_29890096 1.706 ENSMUST00000113762.1
ENSMUST00000113765.1
Odf2

outer dense fiber of sperm tails 2

chr1_+_65311257 1.702 ENSMUST00000027083.6
Pth2r
parathyroid hormone 2 receptor
chr4_+_154869585 1.679 ENSMUST00000079269.7
ENSMUST00000163732.1
ENSMUST00000080559.6
Mmel1


membrane metallo-endopeptidase-like 1


chr7_+_99535439 1.654 ENSMUST00000098266.2
ENSMUST00000179755.1
Arrb1

arrestin, beta 1

chr2_+_29889785 1.638 ENSMUST00000113763.1
ENSMUST00000113757.1
ENSMUST00000113756.1
ENSMUST00000133233.1
ENSMUST00000113759.2
ENSMUST00000113755.1
ENSMUST00000137558.1
ENSMUST00000046571.7
Odf2







outer dense fiber of sperm tails 2







chr11_-_45955465 1.636 ENSMUST00000011398.6
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr10_+_80016653 1.632 ENSMUST00000099501.3
Hmha1
histocompatibility (minor) HA-1
chr3_-_92485886 1.629 ENSMUST00000054599.7
Sprr1a
small proline-rich protein 1A
chr8_-_105637350 1.605 ENSMUST00000182863.1
Gm5914
predicted gene 5914
chr11_+_96282529 1.593 ENSMUST00000125410.1
Hoxb8
homeobox B8
chr13_+_44729794 1.579 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr10_+_80016901 1.571 ENSMUST00000105373.1
Hmha1
histocompatibility (minor) HA-1
chr9_-_54661870 1.570 ENSMUST00000034822.5
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr11_-_34833631 1.561 ENSMUST00000093191.2
Spdl1
spindle apparatus coiled-coil protein 1
chr7_+_125603420 1.539 ENSMUST00000033000.6
Il21r
interleukin 21 receptor
chr14_-_54926784 1.537 ENSMUST00000022813.6
Efs
embryonal Fyn-associated substrate
chr2_+_156840077 1.535 ENSMUST00000081335.6
ENSMUST00000073352.3
Tgif2

TGFB-induced factor homeobox 2

chr1_+_167001457 1.526 ENSMUST00000126198.1
Fam78b
family with sequence similarity 78, member B
chr13_-_49320219 1.525 ENSMUST00000110086.1
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr15_-_100669535 1.494 ENSMUST00000183211.1
Bin2
bridging integrator 2
chr2_+_29890534 1.479 ENSMUST00000113764.3
Odf2
outer dense fiber of sperm tails 2
chr11_+_87760533 1.458 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr4_-_136956784 1.452 ENSMUST00000030420.8
Epha8
Eph receptor A8
chr2_+_29890063 1.443 ENSMUST00000028128.6
Odf2
outer dense fiber of sperm tails 2
chr7_-_25297866 1.423 ENSMUST00000148150.1
ENSMUST00000155118.1
Pafah1b3

platelet-activating factor acetylhydrolase, isoform 1b, subunit 3

chr8_+_120002720 1.415 ENSMUST00000108972.3
Crispld2
cysteine-rich secretory protein LCCL domain containing 2
chr11_-_61494173 1.404 ENSMUST00000101085.2
ENSMUST00000079080.6
ENSMUST00000108714.1
Mapk7


mitogen-activated protein kinase 7


chr12_-_4233958 1.404 ENSMUST00000111169.3
ENSMUST00000020981.5
Cenpo

centromere protein O

chr14_-_33185066 1.366 ENSMUST00000061753.8
ENSMUST00000130509.2
Wdfy4

WD repeat and FYVE domain containing 4

chr5_+_43818893 1.365 ENSMUST00000101237.4
Bst1
bone marrow stromal cell antigen 1
chr11_-_76399107 1.364 ENSMUST00000021204.3
Nxn
nucleoredoxin
chr2_+_105127200 1.362 ENSMUST00000139585.1
Wt1
Wilms tumor 1 homolog
chr17_+_34039437 1.331 ENSMUST00000131134.1
ENSMUST00000087497.4
ENSMUST00000114255.1
ENSMUST00000114252.1
Col11a2



collagen, type XI, alpha 2



chrX_+_159697308 1.320 ENSMUST00000123433.1
Sh3kbp1
SH3-domain kinase binding protein 1
chr13_+_6548154 1.318 ENSMUST00000021611.8
Pitrm1
pitrilysin metallepetidase 1
chr18_+_62180119 1.313 ENSMUST00000067743.1
Gm9949
predicted gene 9949
chr7_+_80186835 1.302 ENSMUST00000107383.1
ENSMUST00000032754.7
Sema4b

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B

chr5_-_115300912 1.301 ENSMUST00000112090.1
Dynll1
dynein light chain LC8-type 1
chr14_+_84443553 1.297 ENSMUST00000071370.5
Pcdh17
protocadherin 17
chr17_-_15041457 1.286 ENSMUST00000097398.4
ENSMUST00000040746.6
ENSMUST00000097400.4
Tcte3

Gm3448
t-complex-associated testis expressed 3

predicted gene 3448
chr5_-_5266038 1.278 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
Cdk14


cyclin-dependent kinase 14


chr11_+_53519725 1.276 ENSMUST00000108987.1
ENSMUST00000121334.1
ENSMUST00000117061.1
Sept8


septin 8


chr5_-_115300957 1.275 ENSMUST00000009157.3
Dynll1
dynein light chain LC8-type 1
chr1_+_72824482 1.270 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr1_-_133906973 1.255 ENSMUST00000126123.1
Optc
opticin
chr7_+_25267669 1.229 ENSMUST00000169266.1
Cic
capicua homolog (Drosophila)
chr6_+_125067913 1.223 ENSMUST00000088292.5
Lpar5
lysophosphatidic acid receptor 5
chr2_-_153444441 1.222 ENSMUST00000109784.1
8430427H17Rik
RIKEN cDNA 8430427H17 gene
chr13_+_44730726 1.220 ENSMUST00000173704.1
ENSMUST00000044608.7
ENSMUST00000173367.1
Jarid2


jumonji, AT rich interactive domain 2


chr11_+_77982710 1.218 ENSMUST00000108360.1
ENSMUST00000049167.7
Phf12

PHD finger protein 12

chr3_+_92288566 1.215 ENSMUST00000090872.4
Sprr2a3
small proline-rich protein 2A3
chr6_+_29694204 1.209 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr2_-_113848655 1.207 ENSMUST00000102545.1
ENSMUST00000110948.1
Arhgap11a

Rho GTPase activating protein 11A

chr17_-_44735612 1.202 ENSMUST00000162373.1
ENSMUST00000162878.1
Runx2

runt related transcription factor 2

chr9_-_44234014 1.199 ENSMUST00000037644.6
Cbl
Casitas B-lineage lymphoma
chrX_+_140956892 1.198 ENSMUST00000112971.1
Atg4a
autophagy related 4A, cysteine peptidase
chrX_-_94542037 1.190 ENSMUST00000026142.7
Maged1
melanoma antigen, family D, 1
chr15_-_56694525 1.170 ENSMUST00000050544.7
Has2
hyaluronan synthase 2
chr11_-_106349389 1.149 ENSMUST00000021056.7
Scn4a
sodium channel, voltage-gated, type IV, alpha
chr2_+_174643534 1.139 ENSMUST00000059452.5
Zfp831
zinc finger protein 831
chr7_-_25297967 1.129 ENSMUST00000005583.5
Pafah1b3
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr11_+_115462464 1.122 ENSMUST00000106532.3
ENSMUST00000092445.5
ENSMUST00000153466.1
Slc16a5


solute carrier family 16 (monocarboxylic acid transporters), member 5


chr1_+_43445736 1.113 ENSMUST00000086421.5
ENSMUST00000114744.1
Nck2

non-catalytic region of tyrosine kinase adaptor protein 2

chr8_-_22125030 1.107 ENSMUST00000169834.1
Nek5
NIMA (never in mitosis gene a)-related expressed kinase 5
chr2_-_113848601 1.102 ENSMUST00000110949.2
Arhgap11a
Rho GTPase activating protein 11A
chr13_-_23551648 1.101 ENSMUST00000102971.1
Hist1h4f
histone cluster 1, H4f
chrX_-_53114530 1.098 ENSMUST00000114843.2
Plac1
placental specific protein 1
chr18_-_62179948 1.097 ENSMUST00000053640.3
Adrb2
adrenergic receptor, beta 2
chr7_+_130865835 1.097 ENSMUST00000075181.4
ENSMUST00000048180.5
Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

chr9_-_50752348 1.088 ENSMUST00000042790.3
Hspb2
heat shock protein 2
chr8_+_121127827 1.079 ENSMUST00000181609.1
Foxl1
forkhead box L1
chr6_-_28830345 1.077 ENSMUST00000171353.1
Lrrc4
leucine rich repeat containing 4
chr2_+_106693185 1.073 ENSMUST00000111063.1
Mpped2
metallophosphoesterase domain containing 2
chr7_+_128129536 1.067 ENSMUST00000033053.6
Itgax
integrin alpha X
chr11_-_70229677 1.066 ENSMUST00000153449.1
ENSMUST00000000326.5
Bcl6b

B cell CLL/lymphoma 6, member B

chr6_-_101377342 1.066 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr15_+_40655020 1.062 ENSMUST00000053467.4
Zfpm2
zinc finger protein, multitype 2
chr6_-_148944750 1.047 ENSMUST00000111562.1
ENSMUST00000081956.5
Fam60a

family with sequence similarity 60, member A

chr11_+_73018986 1.046 ENSMUST00000092937.6
Camkk1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr5_-_38561658 1.045 ENSMUST00000005234.9
Wdr1
WD repeat domain 1
chr5_+_117319292 1.030 ENSMUST00000086464.4
Vsig10
V-set and immunoglobulin domain containing 10
chr8_+_83608175 1.030 ENSMUST00000005620.8
Dnajb1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr8_+_23139157 1.012 ENSMUST00000174435.1
Ank1
ankyrin 1, erythroid
chr17_+_34894515 1.004 ENSMUST00000052778.8
Zbtb12
zinc finger and BTB domain containing 12
chr6_-_52218686 0.998 ENSMUST00000134367.2
Hoxa7
homeobox A7
chr3_-_116253467 0.998 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr4_+_123233556 0.997 ENSMUST00000040821.4
Heyl
hairy/enhancer-of-split related with YRPW motif-like
chr11_+_49901803 0.993 ENSMUST00000093141.5
ENSMUST00000093142.5
Rasgef1c

RasGEF domain family, member 1C

chr18_+_52767994 0.991 ENSMUST00000025413.7
ENSMUST00000163742.2
ENSMUST00000178011.1
Sncaip


synuclein, alpha interacting protein (synphilin)


chr19_+_8802486 0.989 ENSMUST00000172175.1
Zbtb3
zinc finger and BTB domain containing 3
chr2_-_59948155 0.968 ENSMUST00000153136.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr7_+_128246953 0.963 ENSMUST00000167965.1
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chr12_+_32378692 0.963 ENSMUST00000172332.2
Ccdc71l
coiled-coil domain containing 71 like
chr19_+_6384395 0.962 ENSMUST00000035269.8
ENSMUST00000113483.1
Pygm

muscle glycogen phosphorylase

chr2_-_33431324 0.962 ENSMUST00000113158.1
Zbtb34
zinc finger and BTB domain containing 34
chr6_-_41636389 0.957 ENSMUST00000031902.5
Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr14_+_25607797 0.956 ENSMUST00000160229.1
Zmiz1
zinc finger, MIZ-type containing 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 21.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
2.4 7.1 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
2.2 11.2 GO:0002554 serotonin secretion by platelet(GO:0002554)
1.7 5.0 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
1.1 3.4 GO:0030221 basophil differentiation(GO:0030221)
1.1 4.4 GO:0060032 notochord regression(GO:0060032)
1.0 3.1 GO:1903903 positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of establishment of T cell polarity(GO:1903903)
1.0 5.9 GO:0030913 paranodal junction assembly(GO:0030913)
1.0 9.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.9 11.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.9 3.4 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.8 5.8 GO:0071918 urea transmembrane transport(GO:0071918)
0.8 0.8 GO:0060667 fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.8 2.3 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.7 4.4 GO:0032796 uropod organization(GO:0032796)
0.7 2.0 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.7 2.6 GO:0072054 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) renal outer medulla development(GO:0072054) inner medullary collecting duct development(GO:0072061)
0.6 9.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.6 4.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.6 4.8 GO:0070294 renal sodium ion absorption(GO:0070294)
0.6 3.0 GO:0061857 endoplasmic reticulum stress-induced pre-emptive quality control(GO:0061857)
0.6 3.5 GO:0051790 acetate metabolic process(GO:0006083) short-chain fatty acid biosynthetic process(GO:0051790)
0.5 3.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.5 5.6 GO:0035524 proline transmembrane transport(GO:0035524)
0.5 13.5 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.5 2.5 GO:0097167 circadian regulation of translation(GO:0097167)
0.5 2.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.5 2.5 GO:1905522 negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of macrophage migration(GO:1905522)
0.5 1.9 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.5 2.9 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.5 8.4 GO:0070307 lens fiber cell development(GO:0070307)
0.5 14.1 GO:0008340 determination of adult lifespan(GO:0008340)
0.5 1.4 GO:0070375 ERK5 cascade(GO:0070375)
0.5 1.4 GO:2001074 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.4 1.3 GO:1904980 positive regulation of endosome organization(GO:1904980)
0.4 1.3 GO:1990709 presynaptic active zone organization(GO:1990709)
0.4 2.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.4 1.2 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.4 1.8 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.4 2.1 GO:1902287 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.4 1.8 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.3 7.6 GO:0021516 dorsal spinal cord development(GO:0021516)
0.3 2.3 GO:0030421 defecation(GO:0030421)
0.3 0.3 GO:1904908 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.3 4.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.3 9.1 GO:0046685 response to activity(GO:0014823) response to arsenic-containing substance(GO:0046685)
0.3 2.8 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.3 0.9 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.3 0.9 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.3 8.7 GO:0097320 plasma membrane tubulation(GO:0097320)
0.3 1.1 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.3 4.4 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.3 1.7 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.3 1.1 GO:1904504 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure(GO:0002025) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.3 1.9 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.3 1.1 GO:0007525 somatic muscle development(GO:0007525)
0.3 1.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.3 5.3 GO:0042711 maternal behavior(GO:0042711)
0.3 1.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.3 11.4 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779) erythrocyte development(GO:0048821)
0.3 1.0 GO:0030043 actin filament fragmentation(GO:0030043)
0.2 1.0 GO:0061743 motor learning(GO:0061743)
0.2 1.0 GO:0072014 proximal tubule development(GO:0072014)
0.2 1.2 GO:0051697 protein delipidation(GO:0051697)
0.2 2.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.2 2.6 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 0.9 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 1.3 GO:0060023 soft palate development(GO:0060023)
0.2 3.3 GO:0000212 meiotic spindle organization(GO:0000212)
0.2 0.7 GO:0015793 glycerol transport(GO:0015793) cellular response to mercury ion(GO:0071288) cellular response to water stimulus(GO:0071462)
0.2 1.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.2 0.8 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.2 0.6 GO:0046061 dATP catabolic process(GO:0046061)
0.2 1.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.2 0.5 GO:0036292 DNA rewinding(GO:0036292)
0.2 2.9 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.2 1.7 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.2 0.3 GO:0032763 regulation of mast cell cytokine production(GO:0032763) positive regulation of mast cell cytokine production(GO:0032765)
0.2 1.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 2.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 0.8 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.2 0.8 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 0.3 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.2 7.8 GO:0010883 regulation of lipid storage(GO:0010883)
0.2 3.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.2 2.6 GO:0001553 luteinization(GO:0001553)
0.2 2.7 GO:0070831 basement membrane assembly(GO:0070831)
0.2 3.5 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.4 GO:0019045 latent virus replication(GO:0019045) release from viral latency(GO:0019046)
0.1 1.3 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 1.5 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 1.0 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.9 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.5 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 2.1 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1 0.8 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.5 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.1 0.1 GO:0007521 muscle cell fate determination(GO:0007521)
0.1 1.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 3.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.9 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 1.1 GO:0015871 choline transport(GO:0015871)
0.1 1.1 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.1 1.8 GO:0099612 protein localization to axon(GO:0099612)
0.1 8.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 0.7 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.1 0.4 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.1 0.3 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.1 1.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389) negative regulation of inclusion body assembly(GO:0090084)
0.1 1.6 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.3 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.1 1.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.2 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1 1.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.9 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 1.1 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.1 0.2 GO:0072236 metanephric loop of Henle development(GO:0072236)
0.1 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 1.0 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 0.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.3 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 1.4 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.9 GO:1900402 regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter(GO:1900402)
0.1 3.0 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 0.7 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 1.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.1 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.8 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 2.8 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.3 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.1 0.1 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.1 0.7 GO:2000738 positive regulation of stem cell differentiation(GO:2000738)
0.1 2.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.2 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.3 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.1 3.8 GO:0032418 lysosome localization(GO:0032418)
0.1 1.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 0.5 GO:0051013 microtubule severing(GO:0051013)
0.1 0.2 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 0.5 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.1 0.2 GO:0071440 regulation of histone H3-K14 acetylation(GO:0071440)
0.1 1.2 GO:0051604 protein maturation(GO:0051604)
0.1 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 4.2 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 1.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 1.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.4 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.3 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 1.4 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.5 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.3 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.4 GO:0035898 parathyroid hormone secretion(GO:0035898)
0.0 0.2 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.0 1.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 2.3 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.6 GO:0001845 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 1.3 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.0 0.4 GO:0060347 heart trabecula formation(GO:0060347)
0.0 0.9 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.4 GO:0098668 potassium ion export across plasma membrane(GO:0097623) potassium ion export from cell(GO:0098668) membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.0 1.5 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 2.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.1 GO:0050798 activated T cell proliferation(GO:0050798)
0.0 0.1 GO:1900150 regulation of defense response to fungus(GO:1900150) regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035)
0.0 3.2 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.0 0.6 GO:0008272 sulfate transport(GO:0008272)
0.0 0.6 GO:0034508 centromere complex assembly(GO:0034508)
0.0 2.4 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.6 GO:0060065 uterus development(GO:0060065)
0.0 0.1 GO:0034398 telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 1.0 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.3 GO:0019985 translesion synthesis(GO:0019985)
0.0 1.0 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.8 GO:0050727 regulation of inflammatory response(GO:0050727)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.5 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.0 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.3 GO:0048863 stem cell differentiation(GO:0048863)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.3 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.6 GO:0044070 regulation of anion transport(GO:0044070)
0.0 1.0 GO:0051591 response to cAMP(GO:0051591)
0.0 1.1 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.5 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.7 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.5 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.2 GO:0030312 external encapsulating structure(GO:0030312)
1.2 3.6 GO:0034774 secretory granule lumen(GO:0034774) cytoplasmic vesicle lumen(GO:0060205)
0.8 2.3 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.8 3.1 GO:0045160 myosin I complex(GO:0045160)
0.7 2.9 GO:0032280 symmetric synapse(GO:0032280)
0.5 12.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.5 1.8 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.4 12.9 GO:0001891 phagocytic cup(GO:0001891)
0.4 0.9 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.4 3.0 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.3 3.0 GO:0005577 fibrinogen complex(GO:0005577)
0.3 9.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 4.4 GO:0097542 ciliary tip(GO:0097542)
0.3 4.7 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.3 0.9 GO:0005607 laminin-2 complex(GO:0005607)
0.3 2.3 GO:0030478 actin cap(GO:0030478)
0.3 1.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 4.0 GO:0033270 paranode region of axon(GO:0033270)
0.2 2.0 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 1.1 GO:1990769 proximal neuron projection(GO:1990769)
0.2 1.0 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.2 4.9 GO:0005859 muscle myosin complex(GO:0005859)
0.2 3.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 8.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 0.6 GO:0120001 apical plasma membrane urothelial plaque(GO:0120001)
0.2 1.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 4.0 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.9 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 2.4 GO:0033391 chromatoid body(GO:0033391)
0.1 1.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.2 GO:0016600 flotillin complex(GO:0016600)
0.1 9.9 GO:0014704 intercalated disc(GO:0014704)
0.1 0.8 GO:0001652 granular component(GO:0001652)
0.1 4.0 GO:0031012 extracellular matrix(GO:0031012)
0.1 2.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 1.7 GO:0031143 pseudopodium(GO:0031143)
0.1 0.9 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 2.1 GO:0043196 varicosity(GO:0043196)
0.1 0.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.6 GO:0016580 Sin3 complex(GO:0016580)
0.1 2.8 GO:0001533 cornified envelope(GO:0001533)
0.1 0.4 GO:1903440 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648) calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 2.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 2.5 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 3.8 GO:0016235 aggresome(GO:0016235)
0.1 1.0 GO:0036038 MKS complex(GO:0036038)
0.1 1.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 5.9 GO:0005882 intermediate filament(GO:0005882)
0.1 0.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 3.4 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 1.9 GO:0016592 mediator complex(GO:0016592) core mediator complex(GO:0070847)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 2.2 GO:0000791 euchromatin(GO:0000791)
0.0 3.6 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.6 GO:0031011 Ino80 complex(GO:0031011)
0.0 7.7 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 3.2 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 15.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.9 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 5.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 2.0 GO:0042629 mast cell granule(GO:0042629)
0.0 1.1 GO:0008305 integrin complex(GO:0008305)
0.0 2.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 1.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0097346 INO80-type complex(GO:0097346)
0.0 7.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 3.5 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.8 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.0 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.2 GO:0010369 chromocenter(GO:0010369)
0.0 1.4 GO:0000776 kinetochore(GO:0000776)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 1.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.7 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.1 GO:0012506 vesicle membrane(GO:0012506)
0.0 1.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 11.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.6 11.3 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931)
1.6 25.2 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
1.2 3.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
1.1 10.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.0 3.1 GO:0045159 myosin II binding(GO:0045159)
1.0 5.8 GO:0015265 urea channel activity(GO:0015265)
0.9 2.6 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.8 2.3 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.8 3.0 GO:0070052 collagen V binding(GO:0070052)
0.7 3.7 GO:0004966 galanin receptor activity(GO:0004966)
0.7 2.6 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.6 4.0 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.6 1.7 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.5 5.6 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.4 8.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.4 2.9 GO:0001515 opioid peptide activity(GO:0001515)
0.4 6.6 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.4 9.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.4 8.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.4 2.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.4 1.8 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 1.0 GO:0035939 microsatellite binding(GO:0035939)
0.3 1.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.3 0.9 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.3 1.6 GO:0043515 kinetochore binding(GO:0043515)
0.3 1.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 1.1 GO:0031711 beta-adrenergic receptor activity(GO:0004939) bradykinin receptor binding(GO:0031711)
0.3 1.4 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.3 2.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.3 1.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.3 1.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.3 4.9 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.2 1.9 GO:0048495 Roundabout binding(GO:0048495)
0.2 1.6 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 2.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.2 1.8 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 0.7 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.2 4.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 1.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.2 2.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 9.0 GO:0032452 histone demethylase activity(GO:0032452)
0.2 3.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.2 3.0 GO:0015643 toxic substance binding(GO:0015643)
0.2 5.4 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.2 1.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 3.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 2.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 4.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.2 GO:0048185 activin binding(GO:0048185)
0.1 1.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 2.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 12.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.8 GO:0004359 glutaminase activity(GO:0004359)
0.1 1.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.3 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.7 GO:0001595 angiotensin receptor activity(GO:0001595)
0.1 0.8 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.7 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.9 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 1.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.3 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.1 0.6 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.1 0.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.9 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.2 GO:0050145 uridylate kinase activity(GO:0009041) nucleoside phosphate kinase activity(GO:0050145)
0.1 1.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.7 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.4 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.9 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.8 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 1.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.7 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 0.3 GO:0033188 ceramide phosphoethanolamine synthase activity(GO:0002950) sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 1.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 3.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.4 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 2.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 9.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 1.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.5 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 1.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 9.0 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 1.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 1.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.1 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0098505 beta-galactosidase activity(GO:0004565) G-rich strand telomeric DNA binding(GO:0098505)
0.0 1.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.6 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 17.8 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.5 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:0043236 laminin binding(GO:0043236)
0.0 6.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.3 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding(GO:0070530)
0.0 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 2.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.8 PID_BARD1_PATHWAY BARD1 signaling events
0.2 11.7 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 12.3 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.5 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 1.7 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 8.1 PID_PLK1_PATHWAY PLK1 signaling events
0.1 4.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 4.7 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 3.4 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 3.1 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 4.6 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.9 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 3.3 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.1 2.6 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 3.0 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 2.8 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 3.0 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.9 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 6.0 PID_P73PATHWAY p73 transcription factor network
0.1 1.5 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 1.4 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 3.9 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.2 PID_AP1_PATHWAY AP-1 transcription factor network
0.1 1.1 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 2.3 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.1 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 2.0 NABA_COLLAGENS Genes encoding collagen proteins
0.0 2.3 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.9 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.9 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.6 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.7 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 5.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 1.0 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.7 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 0.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.2 PID_MYC_PATHWAY C-MYC pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 10.7 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
1.1 22.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.7 8.8 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.6 3.5 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.4 14.5 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 9.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 2.9 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 3.0 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 4.4 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.1 4.3 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.2 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 3.1 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.3 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.6 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.5 REACTOME_KINESINS Genes involved in Kinesins
0.1 10.3 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.1 1.5 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 1.1 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.2 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.1 1.3 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 4.9 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.1 3.3 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 11.1 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 0.9 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.3 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.1 0.7 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 5.4 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 4.0 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.2 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 1.5 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 4.0 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.8 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.8 REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.5 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.8 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 2.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.7 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.2 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.9 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 0.8 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.8 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 2.0 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.1 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.1 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)