Motif ID: Hdx

Z-value: 2.477


Transcription factors associated with Hdx:

Gene SymbolEntrez IDGene Name
Hdx ENSMUSG00000034551.6 Hdx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hdxmm10_v2_chrX_-_111697069_111697127-0.564.0e-04Click!


Activity profile for motif Hdx.

activity profile for motif Hdx


Sorted Z-values histogram for motif Hdx

Sorted Z-values for motif Hdx



Network of associatons between targets according to the STRING database.



First level regulatory network of Hdx

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_62150810 43.621 ENSMUST00000077719.3
Mup21
major urinary protein 21
chr4_-_60662358 42.257 ENSMUST00000084544.4
ENSMUST00000098046.3
Mup11

major urinary protein 11

chr4_-_60139857 39.801 ENSMUST00000107490.4
ENSMUST00000074700.2
Mup2

major urinary protein 2

chr4_-_60582152 38.304 ENSMUST00000098047.2
Mup10
major urinary protein 10
chr4_-_61303998 37.200 ENSMUST00000071005.8
ENSMUST00000075206.5
Mup14

major urinary protein 14

chr4_-_60421933 36.678 ENSMUST00000107506.2
ENSMUST00000122381.1
ENSMUST00000118759.1
ENSMUST00000122177.1
Mup9



major urinary protein 9



chr4_-_61674094 36.671 ENSMUST00000098040.3
Mup18
major urinary protein 18
chr4_-_60222580 36.115 ENSMUST00000095058.4
ENSMUST00000163931.1
Mup8

major urinary protein 8

chr4_-_61303802 35.654 ENSMUST00000125461.1
Mup14
major urinary protein 14
chr15_+_4727175 16.123 ENSMUST00000162585.1
C6
complement component 6
chr15_+_4727202 15.548 ENSMUST00000161997.1
ENSMUST00000022788.8
C6

complement component 6

chr5_-_87092546 15.352 ENSMUST00000132667.1
ENSMUST00000145617.1
ENSMUST00000094649.4
Ugt2b36


UDP glucuronosyltransferase 2 family, polypeptide B36


chr15_+_4727265 13.402 ENSMUST00000162350.1
C6
complement component 6
chr1_+_182564994 12.991 ENSMUST00000048941.7
ENSMUST00000168514.1
Capn8

calpain 8

chr14_+_37068042 11.174 ENSMUST00000057176.3
Lrit2
leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
chr1_-_139781236 9.319 ENSMUST00000027612.8
ENSMUST00000111989.2
ENSMUST00000111986.2
Gm4788


predicted gene 4788


chr19_-_46672883 9.155 ENSMUST00000026012.7
Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
chr6_-_3968357 8.082 ENSMUST00000031674.8
Tfpi2
tissue factor pathway inhibitor 2
chr15_+_10177623 7.901 ENSMUST00000124470.1
Prlr
prolactin receptor
chr17_-_34743849 7.619 ENSMUST00000069507.8
C4b
complement component 4B (Chido blood group)
chr12_-_98577940 7.486 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr10_+_62071014 7.384 ENSMUST00000053865.5
Gm5424
predicted gene 5424
chr17_+_3397189 7.141 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr5_-_86518578 6.456 ENSMUST00000134179.1
Tmprss11g
transmembrane protease, serine 11g
chr5_-_87535113 6.367 ENSMUST00000120150.1
Sult1b1
sulfotransferase family 1B, member 1
chr2_+_69380431 6.033 ENSMUST00000063690.3
Dhrs9
dehydrogenase/reductase (SDR family) member 9
chr1_+_88070765 5.872 ENSMUST00000073772.4
Ugt1a9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr15_+_10249560 5.676 ENSMUST00000134410.1
Prlr
prolactin receptor
chr1_+_13668739 5.383 ENSMUST00000088542.3
Xkr9
X Kell blood group precursor related family member 9 homolog
chr13_-_56548534 5.174 ENSMUST00000062806.4
Lect2
leukocyte cell-derived chemotaxin 2
chr7_+_13398115 5.005 ENSMUST00000005791.7
Cabp5
calcium binding protein 5
chr1_-_140183404 4.999 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr2_+_120977017 4.990 ENSMUST00000067582.7
Tmem62
transmembrane protein 62
chr1_-_184811170 4.755 ENSMUST00000048462.6
ENSMUST00000110992.2
Marc1

mitochondrial amidoxime reducing component 1

chr17_+_31433054 4.751 ENSMUST00000136384.1
Pde9a
phosphodiesterase 9A
chr16_+_23107413 4.558 ENSMUST00000023599.6
ENSMUST00000168891.1
Eif4a2

eukaryotic translation initiation factor 4A2

chr3_+_62419668 4.496 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr15_-_99087817 4.400 ENSMUST00000064462.3
C1ql4
complement component 1, q subcomponent-like 4
chr9_-_45204083 4.339 ENSMUST00000034599.8
Tmprss4
transmembrane protease, serine 4
chr9_+_70207342 4.116 ENSMUST00000034745.7
Myo1e
myosin IE
chr17_-_35895920 3.940 ENSMUST00000059740.8
2310061I04Rik
RIKEN cDNA 2310061I04 gene
chrX_-_21089229 3.752 ENSMUST00000040667.6
Zfp300
zinc finger protein 300
chr1_-_140183283 3.670 ENSMUST00000111977.1
Cfh
complement component factor h
chr14_-_45477856 3.623 ENSMUST00000141424.1
Fermt2
fermitin family homolog 2 (Drosophila)
chr8_-_84773381 3.577 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr4_+_97777606 3.572 ENSMUST00000075448.6
ENSMUST00000092532.6
Nfia

nuclear factor I/A

chr11_+_97801917 3.420 ENSMUST00000127033.2
Lasp1
LIM and SH3 protein 1
chr10_+_34483400 3.345 ENSMUST00000019913.7
ENSMUST00000170771.1
Frk

fyn-related kinase

chr2_+_116900152 3.320 ENSMUST00000126467.1
ENSMUST00000128305.1
ENSMUST00000155323.1
D330050G23Rik


RIKEN cDNA D330050G23 gene


chr9_-_71168657 3.307 ENSMUST00000113570.1
Aqp9
aquaporin 9
chr14_+_52810934 3.303 ENSMUST00000103646.3
Trav10d
T cell receptor alpha variable 10D
chr6_+_54267131 3.230 ENSMUST00000114402.2
Chn2
chimerin (chimaerin) 2
chr4_+_89137122 3.152 ENSMUST00000058030.7
Mtap
methylthioadenosine phosphorylase
chr17_-_45686899 3.143 ENSMUST00000156254.1
Tmem63b
transmembrane protein 63b
chr2_-_126783416 3.093 ENSMUST00000130356.1
ENSMUST00000028842.2
Usp50

ubiquitin specific peptidase 50

chr8_-_109579056 3.084 ENSMUST00000074898.6
Hp
haptoglobin
chr6_-_4086914 3.054 ENSMUST00000049166.4
Bet1
blocked early in transport 1 homolog (S. cerevisiae)
chr10_-_77799133 3.042 ENSMUST00000178581.1
Gm19668
predicted gene, 19668
chr2_-_90022064 3.037 ENSMUST00000099758.1
Olfr1264
olfactory receptor 1264
chr9_+_3023547 3.033 ENSMUST00000099046.3
Gm10718
predicted gene 10718
chr4_+_145696161 3.032 ENSMUST00000180014.1
Gm13242
predicted gene 13242
chr10_-_127121125 3.007 ENSMUST00000164259.1
ENSMUST00000080975.4
Os9

amplified in osteosarcoma

chr9_+_3025417 2.962 ENSMUST00000075573.6
Gm10717
predicted gene 10717
chr11_+_98446826 2.567 ENSMUST00000019456.4
Grb7
growth factor receptor bound protein 7
chr11_-_69369377 2.561 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr14_-_19418930 2.534 ENSMUST00000177817.1
Gm21738
predicted gene, 21738
chr6_-_130193112 2.451 ENSMUST00000112032.1
ENSMUST00000071554.2
Klra9

killer cell lectin-like receptor subfamily A, member 9

chr18_-_35498856 2.407 ENSMUST00000025215.8
Sil1
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr9_+_3013140 2.337 ENSMUST00000143083.2
Gm10721
predicted gene 10721
chr10_+_127420334 2.297 ENSMUST00000171434.1
R3hdm2
R3H domain containing 2
chr11_-_69685537 2.265 ENSMUST00000018896.7
Tnfsf13
tumor necrosis factor (ligand) superfamily, member 13
chr6_+_34709610 2.223 ENSMUST00000031775.6
Cald1
caldesmon 1
chr3_-_146770603 2.219 ENSMUST00000106138.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr13_+_24327415 2.170 ENSMUST00000167746.1
Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr11_+_115765420 2.147 ENSMUST00000093912.4
ENSMUST00000136720.1
ENSMUST00000103034.3
ENSMUST00000141871.1
2310067B10Rik



RIKEN cDNA 2310067B10 gene



chr2_-_121807024 2.128 ENSMUST00000138157.1
Frmd5
FERM domain containing 5
chr7_-_7337493 2.115 ENSMUST00000072475.6
ENSMUST00000174368.1
Vmn2r30

vomeronasal 2, receptor 30

chr2_-_121806988 2.097 ENSMUST00000110592.1
Frmd5
FERM domain containing 5
chr9_+_3004457 2.081 ENSMUST00000178348.1
Gm11168
predicted gene 11168
chr11_+_117232254 2.081 ENSMUST00000106354.2
Sept9
septin 9
chr3_+_116008220 2.076 ENSMUST00000106502.1
Extl2
exostoses (multiple)-like 2
chr5_-_146963742 2.020 ENSMUST00000125217.1
ENSMUST00000110564.1
ENSMUST00000066675.3
ENSMUST00000016654.2
ENSMUST00000110566.1
ENSMUST00000140526.1
Mtif3





mitochondrial translational initiation factor 3





chrX_+_134187492 2.017 ENSMUST00000064476.4
Arl13a
ADP-ribosylation factor-like 13A
chr7_-_89980935 2.014 ENSMUST00000107234.1
Eed
embryonic ectoderm development
chr2_-_155729359 1.992 ENSMUST00000040833.4
Edem2
ER degradation enhancer, mannosidase alpha-like 2
chr19_-_32061438 1.937 ENSMUST00000096119.4
Asah2
N-acylsphingosine amidohydrolase 2
chr1_+_180101144 1.909 ENSMUST00000133890.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr13_+_60601921 1.904 ENSMUST00000077453.5
Dapk1
death associated protein kinase 1
chr2_-_37359274 1.900 ENSMUST00000009174.8
Pdcl
phosducin-like
chr17_+_33432890 1.866 ENSMUST00000174088.2
Actl9
actin-like 9
chr3_-_34081256 1.807 ENSMUST00000117223.1
ENSMUST00000120805.1
ENSMUST00000011029.5
ENSMUST00000108195.3
Dnajc19



DnaJ (Hsp40) homolog, subfamily C, member 19



chr7_-_7247328 1.782 ENSMUST00000170922.1
Vmn2r29
vomeronasal 2, receptor 29
chr9_+_3037111 1.725 ENSMUST00000177969.1
Gm10715
predicted gene 10715
chr13_+_41249841 1.705 ENSMUST00000165561.2
Smim13
small integral membrane protein 13
chr5_+_107597696 1.670 ENSMUST00000112651.1
ENSMUST00000112654.1
ENSMUST00000065422.5
Rpap2


RNA polymerase II associated protein 2


chr3_+_121671317 1.662 ENSMUST00000098646.3
4930432M17Rik
RIKEN cDNA 4930432M17 gene
chr3_-_146770218 1.650 ENSMUST00000106137.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr7_+_81057589 1.643 ENSMUST00000107348.1
Alpk3
alpha-kinase 3
chr11_+_102285161 1.595 ENSMUST00000156326.1
Tmub2
transmembrane and ubiquitin-like domain containing 2
chr3_-_154330543 1.538 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr2_+_97467657 1.517 ENSMUST00000059049.7
Lrrc4c
leucine rich repeat containing 4C
chr14_-_68655804 1.516 ENSMUST00000111072.1
ENSMUST00000022642.5
Adam28

a disintegrin and metallopeptidase domain 28

chr4_-_43031429 1.488 ENSMUST00000136326.1
Stoml2
stomatin (Epb7.2)-like 2
chr5_+_107597760 1.477 ENSMUST00000112655.1
Rpap2
RNA polymerase II associated protein 2
chr19_+_12460749 1.466 ENSMUST00000081035.7
Mpeg1
macrophage expressed gene 1
chr9_+_3034599 1.425 ENSMUST00000178641.1
Gm17535
predicted gene, 17535
chr9_-_83254460 1.374 ENSMUST00000184080.1
ENSMUST00000184100.1
RP23-341H6.1

RP23-341H6.1

chr7_+_131174400 1.372 ENSMUST00000050586.5
5430419D17Rik
RIKEN cDNA 5430419D17 gene
chr11_-_100050542 1.357 ENSMUST00000007318.1
Krt31
keratin 31
chr14_+_62663665 1.354 ENSMUST00000171692.1
Serpine3
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chrX_+_143518671 1.309 ENSMUST00000134402.1
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr18_-_31949571 1.306 ENSMUST00000064016.5
Gpr17
G protein-coupled receptor 17
chr12_-_81568474 1.289 ENSMUST00000008582.3
Adam21
a disintegrin and metallopeptidase domain 21
chr4_-_134000857 1.281 ENSMUST00000105887.1
ENSMUST00000012262.5
ENSMUST00000144668.1
ENSMUST00000105889.3
Dhdds



dehydrodolichyl diphosphate synthase



chr4_+_3938904 1.189 ENSMUST00000120732.1
ENSMUST00000041122.4
ENSMUST00000121651.1
ENSMUST00000121210.1
ENSMUST00000119307.1
ENSMUST00000123769.1
Chchd7





coiled-coil-helix-coiled-coil-helix domain containing 7





chr4_-_43031370 1.184 ENSMUST00000138030.1
Stoml2
stomatin (Epb7.2)-like 2
chr4_+_124880899 1.182 ENSMUST00000059343.6
Epha10
Eph receptor A10
chr7_-_9841325 1.181 ENSMUST00000170131.1
Vmn2r47
vomeronasal 2, receptor 47
chr16_-_37539781 1.143 ENSMUST00000023525.8
Gtf2e1
general transcription factor II E, polypeptide 1 (alpha subunit)
chr11_-_48946148 1.121 ENSMUST00000104958.1
Psme2b
protease (prosome, macropain) activator subunit 2B
chr5_+_32863700 1.116 ENSMUST00000149350.1
ENSMUST00000118698.1
ENSMUST00000150130.1
ENSMUST00000087897.4
ENSMUST00000119705.1
ENSMUST00000125574.1
ENSMUST00000049780.6
Depdc5






DEP domain containing 5






chr1_+_87327008 1.094 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr7_-_9572288 1.094 ENSMUST00000174433.1
Gm10302
predicted gene 10302
chr1_+_130865669 1.085 ENSMUST00000038829.5
Faim3
Fas apoptotic inhibitory molecule 3
chr5_-_109097864 1.035 ENSMUST00000095922.3
Vmn2r12
vomeronasal 2, receptor 12
chr11_-_35798884 1.013 ENSMUST00000160726.2
Fbll1
fibrillarin-like 1
chr13_+_60602182 1.009 ENSMUST00000044083.7
Dapk1
death associated protein kinase 1
chr12_-_27160311 0.998 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866


predicted gene 9866


chr7_-_128596278 0.992 ENSMUST00000179317.1
Gm7258
predicted gene 7258
chr8_-_41016295 0.982 ENSMUST00000131965.1
Mtus1
mitochondrial tumor suppressor 1
chr10_+_85928491 0.979 ENSMUST00000170396.1
Ascl4
achaete-scute complex homolog 4 (Drosophila)
chr5_+_107437908 0.974 ENSMUST00000094541.2
Btbd8
BTB (POZ) domain containing 8
chr9_+_3005125 0.974 ENSMUST00000179881.1
Gm11168
predicted gene 11168
chr3_-_129755305 0.964 ENSMUST00000029653.2
Egf
epidermal growth factor
chr6_-_143947061 0.942 ENSMUST00000124233.1
Sox5
SRY-box containing gene 5
chrX_+_143518576 0.935 ENSMUST00000033640.7
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr12_-_27160498 0.924 ENSMUST00000182592.1
Gm9866
predicted gene 9866
chr14_-_36968679 0.914 ENSMUST00000067700.6
Ccser2
coiled-coil serine rich 2
chr14_-_72602945 0.913 ENSMUST00000162825.1
Fndc3a
fibronectin type III domain containing 3A
chr16_+_35938470 0.872 ENSMUST00000114878.1
Parp9
poly (ADP-ribose) polymerase family, member 9
chr11_+_4257557 0.865 ENSMUST00000066283.5
Lif
leukemia inhibitory factor
chr9_+_3036877 0.859 ENSMUST00000155807.2
Gm10715
predicted gene 10715
chr16_-_50330987 0.851 ENSMUST00000114488.1
Bbx
bobby sox homolog (Drosophila)
chr14_+_53845234 0.835 ENSMUST00000103674.4
Trav19
T cell receptor alpha variable 19
chr4_+_43406435 0.831 ENSMUST00000098106.2
ENSMUST00000139198.1
Rusc2

RUN and SH3 domain containing 2

chr10_-_130429612 0.829 ENSMUST00000171811.2
Vmn2r85
vomeronasal 2, receptor 85
chr9_+_94669876 0.824 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr6_-_57535422 0.811 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr1_+_180109192 0.810 ENSMUST00000143176.1
ENSMUST00000135056.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr6_-_143947092 0.807 ENSMUST00000144289.1
ENSMUST00000111748.1
Sox5

SRY-box containing gene 5

chr9_+_3000922 0.805 ENSMUST00000151376.2
Gm10722
predicted gene 10722
chr11_-_98193260 0.789 ENSMUST00000092735.5
ENSMUST00000107545.2
Med1

mediator complex subunit 1

chr7_-_42933789 0.789 ENSMUST00000163803.1
Vmn2r63
vomeronasal 2, receptor 63
chr9_+_3015654 0.774 ENSMUST00000099050.3
Gm10720
predicted gene 10720
chr5_-_26004798 0.769 ENSMUST00000168875.1
Gm1979
predicted gene 1979
chr8_+_109493982 0.738 ENSMUST00000034162.6
Pmfbp1
polyamine modulated factor 1 binding protein 1
chr5_-_26089291 0.725 ENSMUST00000094946.4
Gm10471
predicted gene 10471
chr4_-_97584605 0.694 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr13_-_67729109 0.677 ENSMUST00000073157.6
Zfp71-rs1
zinc finger protein 71, related sequence
chr5_-_25926215 0.676 ENSMUST00000167847.2
Gm21655
predicted gene, 21655
chr13_+_43370710 0.664 ENSMUST00000066804.4
Sirt5
sirtuin 5
chr13_-_66355385 0.662 ENSMUST00000099416.3
Vmn2r-ps104
vomeronasal 2, receptor, pseudogene 104
chr14_+_13454010 0.657 ENSMUST00000112656.2
Synpr
synaptoporin
chr5_-_107597577 0.656 ENSMUST00000100949.3
ENSMUST00000078021.6
Glmn

glomulin, FKBP associated protein

chr5_+_26257691 0.638 ENSMUST00000074148.6
Gm7361
predicted gene 7361
chr18_+_77375065 0.637 ENSMUST00000123410.1
Loxhd1
lipoxygenase homology domains 1
chr16_+_14705832 0.636 ENSMUST00000023356.6
Snai2
snail homolog 2 (Drosophila)
chr7_+_13398150 0.615 ENSMUST00000117400.1
Cabp5
calcium binding protein 5
chr5_-_25954344 0.607 ENSMUST00000162387.4
Gm21671
predicted gene, 21671
chr16_-_50432340 0.605 ENSMUST00000066037.6
ENSMUST00000089399.4
ENSMUST00000089404.3
ENSMUST00000114477.1
ENSMUST00000138166.1
Bbx




bobby sox homolog (Drosophila)




chr8_-_85025268 0.591 ENSMUST00000064314.8
Asna1
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr16_+_22951072 0.582 ENSMUST00000023590.8
Hrg
histidine-rich glycoprotein
chr9_+_45055166 0.566 ENSMUST00000114664.1
ENSMUST00000093856.3
Mpzl3

myelin protein zero-like 3

chr1_+_87327044 0.566 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr9_+_87729285 0.553 ENSMUST00000181359.1
D030062O11Rik
RIKEN cDNA D030062O11 gene
chr5_-_26105362 0.542 ENSMUST00000063524.2
5031410I06Rik
RIKEN cDNA 5031410I06 gene
chr5_-_15714236 0.537 ENSMUST00000095005.5
ENSMUST00000179506.1
Speer4c

spermatogenesis associated glutamate (E)-rich protein 4c

chr5_-_109192107 0.523 ENSMUST00000053253.8
Vmn2r13
vomeronasal 2, receptor 13
chr5_-_26121421 0.519 ENSMUST00000088236.3
Gm10220
predicted gene 10220
chr5_-_14938429 0.513 ENSMUST00000159973.2
Speer4e
spermatogenesis associated glutamate (E)-rich protein 4e
chr5_-_26039506 0.502 ENSMUST00000079447.2
Speer4a
spermatogenesis associated glutamate (E)-rich protein 4a
chr6_-_130699016 0.501 ENSMUST00000182643.1
Gm26919
predicted gene, 26919
chr2_-_41789078 0.471 ENSMUST00000167270.2
Lrp1b
low density lipoprotein-related protein 1B (deleted in tumors)
chr15_+_102954427 0.461 ENSMUST00000001701.3
Hoxc11
homeobox C11
chr10_-_130497379 0.455 ENSMUST00000164227.2
Vmn2r87
vomeronasal 2, receptor 87
chr5_-_14978935 0.428 ENSMUST00000096953.4
Gm10354
predicted gene 10354
chr3_-_145099024 0.425 ENSMUST00000040465.6
Clca5
chloride channel calcium activated 5
chr5_+_15619064 0.421 ENSMUST00000095006.2
Speer4d
spermatogenesis associated glutamate (E)-rich protein 4d
chr18_-_39489157 0.417 ENSMUST00000131885.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr1_+_87326997 0.399 ENSMUST00000027475.8
Gigyf2
GRB10 interacting GYF protein 2
chr7_-_41872670 0.396 ENSMUST00000171671.1
Vmn2r58
vomeronasal 2, receptor 58
chr4_-_97584612 0.389 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr7_-_8260599 0.388 ENSMUST00000066317.4
Vmn2r43
vomeronasal 2, receptor 43
chr9_+_45055211 0.387 ENSMUST00000114663.2
Mpzl3
myelin protein zero-like 3
chr16_-_4624984 0.383 ENSMUST00000014445.6
Pam16
presequence translocase-asssociated motor 16 homolog (S. cerevisiae)
chr11_+_95666957 0.360 ENSMUST00000125172.1
ENSMUST00000036374.5
Phb

prohibitin

chr7_-_44257204 0.351 ENSMUST00000012921.7
Acpt
acid phosphatase, testicular
chr5_-_129879038 0.351 ENSMUST00000026617.6
Phkg1
phosphorylase kinase gamma 1
chr5_-_86518562 0.340 ENSMUST00000140095.1
Tmprss11g
transmembrane protease, serine 11g
chr7_-_9953585 0.332 ENSMUST00000165611.1
Vmn2r48
vomeronasal 2, receptor 48

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
9.0 45.1 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
3.8 42.3 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
2.3 13.6 GO:0038161 prolactin signaling pathway(GO:0038161)
1.5 4.6 GO:0001172 transcription, RNA-templated(GO:0001172)
1.1 6.4 GO:0006068 ethanol catabolic process(GO:0006068)
1.0 3.1 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
1.0 8.7 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.9 2.7 GO:1900210 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
0.9 6.0 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.8 3.2 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.8 2.3 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.7 4.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.7 2.0 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.7 3.3 GO:0015855 purine nucleobase transport(GO:0006863) nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.6 1.9 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.6 4.8 GO:0042126 nitrate metabolic process(GO:0042126)
0.5 2.2 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.5 9.2 GO:0042448 progesterone metabolic process(GO:0042448)
0.5 7.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.5 5.9 GO:0009812 flavonoid metabolic process(GO:0009812)
0.4 3.0 GO:0006621 protein retention in ER lumen(GO:0006621)
0.4 2.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.4 0.4 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.4 3.9 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.3 3.1 GO:0009301 snRNA transcription(GO:0009301)
0.3 2.0 GO:0032790 ribosome disassembly(GO:0032790)
0.3 2.0 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.3 4.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 1.0 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.2 3.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 1.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 1.0 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.2 3.6 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 1.7 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.2 0.6 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.2 4.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 3.6 GO:0072189 ureter development(GO:0072189)
0.2 2.9 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.9 GO:0048861 histone H3-K27 acetylation(GO:0043974) leukemia inhibitory factor signaling pathway(GO:0048861) positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 1.3 GO:0016093 polyprenol metabolic process(GO:0016093)
0.1 3.6 GO:0033622 integrin activation(GO:0033622)
0.1 0.2 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.1 7.6 GO:0006956 complement activation(GO:0006956)
0.1 2.6 GO:0034063 stress granule assembly(GO:0034063)
0.1 4.4 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.1 1.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 2.1 GO:1902857 positive regulation of non-motile cilium assembly(GO:1902857)
0.1 13.0 GO:0007586 digestion(GO:0007586)
0.1 0.4 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 2.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 2.2 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 1.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.8 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719)
0.1 0.9 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.0 2.3 GO:0007097 nuclear migration(GO:0007097)
0.0 0.7 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.5 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.2 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0 8.1 GO:0007596 blood coagulation(GO:0007596)
0.0 2.2 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.9 GO:0060009 Sertoli cell development(GO:0060009)
0.0 2.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 1.0 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 1.8 GO:0048806 genitalia development(GO:0048806)
0.0 5.2 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 1.5 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.3 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 1.6 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 1.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 3.1 GO:0016579 protein deubiquitination(GO:0016579)
0.0 2.6 GO:0007098 centrosome cycle(GO:0007098)
0.0 1.5 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 4.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.2 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 6.2 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.0 0.2 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 1.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.8 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.1 GO:2000653 regulation of genetic imprinting(GO:2000653)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 45.1 GO:0005579 membrane attack complex(GO:0005579)
0.7 4.1 GO:0032437 cuticular plate(GO:0032437)
0.6 3.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 3.0 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.3 3.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 1.5 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 2.2 GO:0030478 actin cap(GO:0030478)
0.2 7.6 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.2 1.1 GO:1990130 GATOR1 complex(GO:1990130)
0.2 2.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 0.6 GO:0032010 phagolysosome(GO:0032010)
0.2 1.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 2.1 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 2.1 GO:0031105 septin complex(GO:0031105)
0.1 0.4 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 2.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 2.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 2.7 GO:0042101 T cell receptor complex(GO:0042101)
0.1 3.1 GO:0005801 cis-Golgi network(GO:0005801)
0.1 8.7 GO:0072562 blood microparticle(GO:0072562)
0.1 3.6 GO:0031941 filamentous actin(GO:0031941)
0.1 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 4.4 GO:0005581 collagen trimer(GO:0005581)
0.0 6.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462) Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 2.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285)
0.0 0.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 4.0 GO:0043204 perikaryon(GO:0043204)
0.0 4.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.8 GO:0016592 mediator complex(GO:0016592) core mediator complex(GO:0070847)
0.0 2.2 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 2.7 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 7.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.6 GO:0032421 stereocilium(GO:0032420) stereocilium bundle(GO:0032421)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 13.6 GO:0004925 prolactin receptor activity(GO:0004925)
1.6 4.8 GO:0008940 nitrate reductase activity(GO:0008940)
1.5 4.6 GO:0003968 RNA-directed 5'-3' RNA polymerase activity(GO:0003968)
1.3 9.0 GO:0001851 complement component C3b binding(GO:0001851)
1.3 6.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
1.1 3.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.0 6.0 GO:0047035 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
1.0 7.6 GO:0001849 complement component C1q binding(GO:0001849)
0.7 2.2 GO:0030338 CMP-N-acetylneuraminate monooxygenase activity(GO:0030338)
0.7 2.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.7 3.3 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.6 21.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.5 7.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.4 3.1 GO:0030492 hemoglobin binding(GO:0030492)
0.3 3.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.3 1.9 GO:0017040 ceramidase activity(GO:0017040)
0.3 2.7 GO:1901612 cardiolipin binding(GO:1901612)
0.3 2.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2 1.9 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 2.0 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 0.9 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.2 4.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2 0.8 GO:0036033 mediator complex binding(GO:0036033)
0.2 4.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 0.5 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.2 7.0 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.2 1.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 2.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 5.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 2.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 3.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.4 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 1.3 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 0.8 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 2.1 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.3 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 10.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.0 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 3.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.2 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.1 0.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 2.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.7 GO:0070403 NAD+ binding(GO:0070403)
0.0 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 4.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 2.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 2.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 4.1 GO:0003774 motor activity(GO:0003774)
0.0 3.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 2.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 4.4 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 14.5 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.1 3.9 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 3.0 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.6 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 2.9 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 2.2 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.1 3.6 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 5.2 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 2.3 PID_CDC42_PATHWAY CDC42 signaling events
0.0 5.2 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 3.2 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 1.5 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 3.2 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 0.8 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 53.7 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.7 9.2 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.7 13.6 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.6 7.5 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.5 6.4 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.5 5.9 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.3 3.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 2.9 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 3.2 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.2 2.0 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 4.6 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.2 3.9 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 4.8 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 1.3 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 2.2 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.9 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 2.2 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.0 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 4.6 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.1 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 2.3 REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 2.1 REACTOME_SIGNALING_BY_SCF_KIT Genes involved in Signaling by SCF-KIT
0.0 0.4 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones