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GSE58827: Dynamics of the Mouse Liver

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Results for Hes1

Z-value: 0.65

Motif logo

Transcription factors associated with Hes1

Gene Symbol Gene ID Gene Info
ENSMUSG00000022528.7 hes family bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hes1mm10_v2_chr16_+_30065333_300653510.222.1e-01Click!

Activity profile of Hes1 motif

Sorted Z-values of Hes1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_12026237 12.74 ENSMUST00000150972.1
growth factor receptor bound protein 10
chr11_-_12026732 11.43 ENSMUST00000143915.1
growth factor receptor bound protein 10
chr14_-_79301623 8.53 ENSMUST00000022595.7
regulator of cell cycle
chr17_-_26199008 5.69 ENSMUST00000142410.1
ENSMUST00000120333.1
ENSMUST00000039113.7
protein disulfide isomerase associated 2
chr8_+_23139064 4.48 ENSMUST00000033947.8
ankyrin 1, erythroid
chr10_+_75571522 4.40 ENSMUST00000143226.1
ENSMUST00000124259.1
gamma-glutamyltransferase 1
chr19_-_24555819 4.40 ENSMUST00000112673.2
ENSMUST00000025800.8
phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
chr15_+_89322969 3.21 ENSMUST00000066991.5
adrenomedullin 2
chr11_+_95010277 2.99 ENSMUST00000124735.1
sterile alpha motif domain containing 14
chr8_+_23139030 2.91 ENSMUST00000121075.1
ankyrin 1, erythroid
chr14_-_51146757 2.56 ENSMUST00000080126.2
ribonuclease, RNase A family, 1 (pancreatic)
chr11_+_116531744 2.39 ENSMUST00000106387.2
ENSMUST00000100201.3
sphingosine kinase 1
chr17_+_28769307 2.36 ENSMUST00000004986.6
mitogen-activated protein kinase 13
chr7_+_78914216 2.20 ENSMUST00000120331.2
interferon-stimulated protein
chr1_-_189688074 2.08 ENSMUST00000171929.1
ENSMUST00000165962.1
centromere protein F
chr7_+_78913765 2.07 ENSMUST00000038142.8
interferon-stimulated protein
chr8_+_71406003 2.06 ENSMUST00000119976.1
ENSMUST00000120725.1
ankyrin repeat and LEM domain containing 1
chr7_+_99535652 2.06 ENSMUST00000032995.8
ENSMUST00000162404.1
arrestin, beta 1
chr12_-_17176888 2.02 ENSMUST00000170580.1
potassium voltage-gated channel, subfamily F, member 1
chr14_-_60177482 1.95 ENSMUST00000140924.1
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr7_+_79660196 1.88 ENSMUST00000035977.7
TOPBP1-interacting checkpoint and replication regulator
chr12_+_110279228 1.81 ENSMUST00000097228.4
deiodinase, iodothyronine type III
chr19_+_10018265 1.72 ENSMUST00000131407.1
RAB3A interacting protein (rabin3)-like 1
chr11_-_102925086 1.68 ENSMUST00000021311.9
kinesin family member 18B
chr6_-_38299236 1.59 ENSMUST00000058524.2
zinc finger CCCH-type, antiviral 1-like
chr19_+_10018193 1.58 ENSMUST00000113161.2
ENSMUST00000117641.1
RAB3A interacting protein (rabin3)-like 1
chr3_+_157566868 1.57 ENSMUST00000041175.6
ENSMUST00000173533.1
prostaglandin E receptor 3 (subtype EP3)
chr11_+_11685909 1.57 ENSMUST00000065433.5
IKAROS family zinc finger 1
chr2_-_35979624 1.46 ENSMUST00000028248.4
ENSMUST00000112976.2
tubulin tyrosine ligase-like family, member 11
chr2_-_131160006 1.45 ENSMUST00000103188.3
ENSMUST00000133602.1
ENSMUST00000028800.5
RIKEN cDNA 1700037H04 gene
chr14_+_65266701 1.44 ENSMUST00000169656.1
F-box protein 16
chr2_+_103970115 1.43 ENSMUST00000111143.1
ENSMUST00000138815.1
LIM domain only 2
chr12_-_50649190 1.39 ENSMUST00000002765.7
protein kinase D1
chr11_+_113619318 1.39 ENSMUST00000146390.2
ENSMUST00000106630.1
somatostatin receptor 2
chr11_+_69095217 1.37 ENSMUST00000101004.2
period circadian clock 1
chr2_+_30286383 1.37 ENSMUST00000064447.5
nucleoporin 188
chr6_-_70792155 1.34 ENSMUST00000066134.5
ribose 5-phosphate isomerase A
chr12_-_111485808 1.33 ENSMUST00000010673.5
predicted gene 266
chr6_+_124829540 1.31 ENSMUST00000150120.1
cell division cycle associated 3
chr3_+_28781305 1.27 ENSMUST00000060500.7
eukaryotic translation initiation factor 5A2
chr11_+_120608469 1.26 ENSMUST00000106194.1
ENSMUST00000106195.2
neuropeptide B
chr13_-_68999518 1.23 ENSMUST00000022013.7
adenylate cyclase 2
chr11_+_72042455 1.23 ENSMUST00000021164.3
family with sequence similarity 64, member A
chr5_-_52566264 1.18 ENSMUST00000039750.5
leucine-rich repeat LGI family, member 2
chr2_+_103970221 1.17 ENSMUST00000111140.2
ENSMUST00000111139.2
LIM domain only 2
chr4_-_133887765 1.16 ENSMUST00000003741.9
ENSMUST00000105894.4
ribosomal protein S6 kinase polypeptide 1
chr2_+_127336152 1.15 ENSMUST00000028846.6
dual specificity phosphatase 2
chr2_+_156840966 1.15 ENSMUST00000109564.1
TGFB-induced factor homeobox 2
chr5_+_118027743 1.14 ENSMUST00000031304.7
tescalcin
chr1_+_63176818 1.13 ENSMUST00000129339.1
eukaryotic translation elongation factor 1 beta 2
chrX_+_53724826 1.11 ENSMUST00000069209.1
RIKEN cDNA 4930502E18 gene
chr18_-_34931931 1.08 ENSMUST00000180351.1
eukaryotic translation termination factor 1
chr11_-_120348513 1.05 ENSMUST00000071555.6
actin, gamma, cytoplasmic 1
chr7_+_99535439 1.04 ENSMUST00000098266.2
ENSMUST00000179755.1
arrestin, beta 1
chr11_+_120608492 1.04 ENSMUST00000061309.4
neuropeptide B
chr3_-_144760841 1.02 ENSMUST00000059091.5
chloride channel calcium activated 1
chr16_-_20425881 1.02 ENSMUST00000077867.3
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr15_-_73184840 0.97 ENSMUST00000044113.10
argonaute RISC catalytic subunit 2
chr18_-_32036941 0.96 ENSMUST00000134663.1
myosin VIIB
chr4_-_53262547 0.95 ENSMUST00000098075.2
expressed sequence AI427809
chr17_-_7827289 0.95 ENSMUST00000167580.1
ENSMUST00000169126.1
fibronectin type III domain containing 1
chr9_+_124102110 0.94 ENSMUST00000168841.1
ENSMUST00000055918.6
chemokine (C-C motif) receptor 2
chr6_-_65144908 0.92 ENSMUST00000031982.4
hematopoietic prostaglandin D synthase
chr2_+_30286406 0.92 ENSMUST00000138666.1
ENSMUST00000113634.2
nucleoporin 188
chr2_+_72476225 0.92 ENSMUST00000157019.1
cell division cycle associated 7
chr18_+_67800101 0.91 ENSMUST00000025425.5
centrosomal protein 192
chr13_-_23551648 0.90 ENSMUST00000102971.1
histone cluster 1, H4f
chr7_+_26061495 0.88 ENSMUST00000005669.7
cytochrome P450, family 2, subfamily b, polypeptide 13
chr11_+_116198853 0.87 ENSMUST00000021130.6
TEN1 telomerase capping complex subunit
chr6_-_12749193 0.85 ENSMUST00000046121.6
ENSMUST00000172356.1
thrombospondin, type I, domain containing 7A
chrX_+_71555918 0.85 ENSMUST00000072699.6
ENSMUST00000114582.2
ENSMUST00000015361.4
ENSMUST00000088874.3
high mobility group box 3
chr8_+_83608175 0.83 ENSMUST00000005620.8
DnaJ (Hsp40) homolog, subfamily B, member 1
chr3_-_90052463 0.83 ENSMUST00000029553.9
ENSMUST00000064639.8
ENSMUST00000090908.6
ubiquitin associated protein 2-like
chr2_+_72476159 0.82 ENSMUST00000102691.4
cell division cycle associated 7
chr11_-_108343917 0.82 ENSMUST00000059595.4
protein kinase C, alpha
chr7_-_12775658 0.79 ENSMUST00000046245.5
zinc finger and SCAN domain containing 18
chr5_+_123076275 0.78 ENSMUST00000067505.8
ENSMUST00000111619.3
ENSMUST00000160344.1
transmembrane protein 120B
chr11_-_11462408 0.77 ENSMUST00000020413.3
zona pellucida binding protein
chr13_+_46418266 0.76 ENSMUST00000037923.3
RNA binding motif protein 24
chr12_+_116077720 0.74 ENSMUST00000011315.3
vasoactive intestinal peptide receptor 2
chr18_-_53418004 0.74 ENSMUST00000025419.7
peptidylprolyl isomerase C
chr5_+_26817357 0.74 ENSMUST00000071500.6
dipeptidylpeptidase 6
chr13_-_47106176 0.74 ENSMUST00000021807.6
ENSMUST00000135278.1
DEK oncogene (DNA binding)
chr7_+_47050628 0.72 ENSMUST00000010451.5
transmembrane protein 86A
chr17_+_35861343 0.71 ENSMUST00000172931.1
nurim (nuclear envelope membrane protein)
chr2_+_105127200 0.68 ENSMUST00000139585.1
Wilms tumor 1 homolog
chr3_+_108085976 0.68 ENSMUST00000070502.1
predicted gene 12500
chr17_+_23803179 0.68 ENSMUST00000088621.4
serine/arginine repetitive matrix 2
chrX_-_106221145 0.66 ENSMUST00000113495.2
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr7_+_24862193 0.66 ENSMUST00000052897.4
ENSMUST00000170837.2
predicted pseudogene 9844
predicted pseudogene 9844
chrX_-_73930751 0.64 ENSMUST00000155597.1
ENSMUST00000114379.1
renin binding protein
chr3_+_107036156 0.63 ENSMUST00000052718.3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr4_+_130360132 0.62 ENSMUST00000105994.3
small nuclear ribonucleoprotein 40 (U5)
chr3_-_158031705 0.62 ENSMUST00000072875.8
serine/arginine-rich splicing factor 11
chr16_-_17576631 0.62 ENSMUST00000164545.1
ENSMUST00000164490.1
ENSMUST00000172164.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 4
chr7_-_62420139 0.61 ENSMUST00000094340.3
makorin, ring finger protein, 3
chr1_-_135105210 0.61 ENSMUST00000044828.7
leucine-rich repeat-containing G protein-coupled receptor 6
chr15_+_12117848 0.59 ENSMUST00000128475.1
ENSMUST00000134277.1
zinc finger RNA binding protein
chr12_+_85599388 0.59 ENSMUST00000050687.6
Jun dimerization protein 2
chr2_+_162931520 0.57 ENSMUST00000130411.1
serine/arginine-rich splicing factor 6
chr11_-_109473598 0.57 ENSMUST00000070152.5
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr4_-_58206596 0.57 ENSMUST00000042850.8
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr2_+_105126505 0.57 ENSMUST00000143043.1
Wilms tumor 1 homolog
chr19_-_4615647 0.56 ENSMUST00000113822.2
leucine rich repeat and fibronectin type III domain containing 4
chr4_+_154960915 0.56 ENSMUST00000049621.6
hairy and enhancer of split 5 (Drosophila)
chr11_-_45955465 0.55 ENSMUST00000011398.6
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr5_-_65537139 0.55 ENSMUST00000149167.1
small integral membrane protein 14
chr11_+_84957775 0.55 ENSMUST00000103194.3
carbonic anhydrase 4
chr9_-_35558522 0.54 ENSMUST00000034612.5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr3_-_146685592 0.54 ENSMUST00000125965.1
sterile alpha motif domain containing 13
chr1_+_75375271 0.54 ENSMUST00000087122.5
SPEG complex locus
chr4_-_43562397 0.54 ENSMUST00000030187.7
talin 1
chr1_-_160792908 0.51 ENSMUST00000028049.7
RAB GTPase activating protein 1-like
chr5_+_34369909 0.51 ENSMUST00000180376.1
family with sequence similarity 193, member A
chr16_-_90810365 0.51 ENSMUST00000140920.1
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr3_+_54693088 0.51 ENSMUST00000170552.1
suppressor of Ty 20
chr10_-_123196916 0.50 ENSMUST00000020334.7
ubiquitin specific peptidase 15
chr14_+_75284343 0.48 ENSMUST00000022577.5
zinc finger CCCH type containing 13
chr15_-_95528228 0.48 ENSMUST00000075275.2
NEL-like 2
chr4_-_135353126 0.47 ENSMUST00000030613.4
ENSMUST00000131373.1
serine/arginine repetitive matrix 1
chr4_+_108460000 0.47 ENSMUST00000097925.2
zinc finger, CCHC domain containing 11
chr7_-_126799134 0.47 ENSMUST00000087566.4
aldolase A, fructose-bisphosphate
chr5_+_146948640 0.46 ENSMUST00000146511.1
ENSMUST00000132102.1
general transcription factor III A
chr3_-_88503187 0.46 ENSMUST00000120377.1
lamin A
chr2_-_140170528 0.46 ENSMUST00000046030.7
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr5_+_123394782 0.46 ENSMUST00000111596.1
ENSMUST00000068237.5
MLX interacting protein
chr8_-_36249292 0.46 ENSMUST00000065297.5
LON peptidase N-terminal domain and ring finger 1
chr4_+_137277489 0.46 ENSMUST00000045747.4
wingless-related MMTV integration site 4
chr10_-_30842765 0.45 ENSMUST00000019924.8
hairy/enhancer-of-split related with YRPW motif 2
chr18_+_82910863 0.45 ENSMUST00000171238.1
zinc finger protein 516
chr17_+_3114957 0.45 ENSMUST00000076734.6
SR-related CTD-associated factor 8
chr7_-_126799163 0.44 ENSMUST00000032934.5
aldolase A, fructose-bisphosphate
chr2_+_157914618 0.44 ENSMUST00000109523.1
V-set and transmembrane domain containing 2-like
chrX_-_157598642 0.44 ENSMUST00000112522.2
ENSMUST00000179062.1
membrane-bound transcription factor peptidase, site 2
Yy2 transcription factor
chr15_+_84923383 0.43 ENSMUST00000165443.2
nucleoporin 50
chr11_+_3202612 0.42 ENSMUST00000110049.1
eukaryotic translation initiation factor 4E nuclear import factor 1
chrX_+_20688379 0.42 ENSMUST00000033380.6
cyclin-dependent kinase 16
chr11_+_29547950 0.42 ENSMUST00000020753.3
clathrin heavy chain linker domain containing 1
chr7_-_126502312 0.41 ENSMUST00000166682.2
ataxin 2-like
chr16_+_30008657 0.40 ENSMUST00000181485.1
RIKEN cDNA 4632428C04 gene
chr9_+_57072024 0.40 ENSMUST00000169879.1
transcriptional regulator, SIN3A (yeast)
chr4_+_107434617 0.40 ENSMUST00000135835.1
ENSMUST00000046005.2
GLIS family zinc finger 1
chr5_-_36695969 0.39 ENSMUST00000031091.9
ENSMUST00000140063.1
DNA segment, Chr 5, ERATO Doi 579, expressed
chr11_-_106788845 0.39 ENSMUST00000123339.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
chr3_+_54692805 0.38 ENSMUST00000029315.8
suppressor of Ty 20
chr4_-_135353164 0.37 ENSMUST00000084846.5
ENSMUST00000136342.2
ENSMUST00000105861.1
serine/arginine repetitive matrix 1
chr1_+_153652943 0.37 ENSMUST00000041776.5
regulator of G-protein signaling 8
chr3_-_102204576 0.37 ENSMUST00000159388.1
vang-like 1 (van gogh, Drosophila)
chr11_-_45955183 0.37 ENSMUST00000109254.1
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr8_-_87959560 0.36 ENSMUST00000109655.2
zinc finger protein 423
chr11_+_106789235 0.36 ENSMUST00000103068.3
ENSMUST00000018516.4
centrosomal protein 95
chr3_-_88503331 0.35 ENSMUST00000029699.6
lamin A
chr6_-_31563978 0.35 ENSMUST00000026698.7
podocalyxin-like
chr7_-_46795661 0.35 ENSMUST00000123725.1
Hermansky-Pudlak syndrome 5 homolog (human)
chr11_-_106789157 0.35 ENSMUST00000129585.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
chr4_+_5644084 0.35 ENSMUST00000054857.6
family with sequence similarity 110, member B
chr2_+_153345809 0.34 ENSMUST00000109790.1
additional sex combs like 1
chr1_-_75210732 0.33 ENSMUST00000113623.1
galactosidase, beta 1-like
chr2_-_85196697 0.33 ENSMUST00000099930.2
ENSMUST00000111601.1
leucine rich repeat containing 55
chr1_-_175692624 0.33 ENSMUST00000027809.7
opsin 3
chr4_-_58553553 0.33 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
lysophosphatidic acid receptor 1
chr5_-_139484420 0.32 ENSMUST00000150992.1
zinc finger, AN1-type domain 2A
chr9_+_106429537 0.32 ENSMUST00000059802.6
ribosomal protein L29
chr11_-_29547820 0.32 ENSMUST00000102844.3
ribosomal protein S27A
chr10_+_36974558 0.32 ENSMUST00000105510.1
histone deacetylase 2
chr17_+_83350925 0.31 ENSMUST00000096766.4
ENSMUST00000112363.2
ENSMUST00000049503.8
echinoderm microtubule associated protein like 4
chr13_-_43304153 0.31 ENSMUST00000055341.5
glucose-fructose oxidoreductase domain containing 1
chr4_-_123904826 0.31 ENSMUST00000181292.1
predicted gene, 26606
chr7_-_35585577 0.30 ENSMUST00000069912.4
regulator of G-protein signalling 9 binding protein
chr2_+_149830788 0.30 ENSMUST00000109935.1
synapse differentiation inducing 1
chr17_+_57105385 0.30 ENSMUST00000039490.7
tumor necrosis factor (ligand) superfamily, member 9
chr10_-_12923100 0.29 ENSMUST00000181073.1
RIKEN cDNA B230208H11 gene
chr10_+_40349265 0.29 ENSMUST00000044672.4
ENSMUST00000095743.2
cyclin-dependent kinase 19
chr17_-_6961156 0.29 ENSMUST00000063683.6
T cell activation GTPase activating protein 1
chr11_-_116624200 0.29 ENSMUST00000103029.3
rhomboid 5 homolog 2 (Drosophila)
chr11_-_116110211 0.29 ENSMUST00000106441.1
ENSMUST00000021120.5
tripartite motif-containing 47
chr7_-_99483645 0.28 ENSMUST00000107096.1
ENSMUST00000032998.6
ribosomal protein S3
chr17_+_29032664 0.28 ENSMUST00000130216.1
serine/arginine-rich splicing factor 3
chr7_-_101864093 0.27 ENSMUST00000106981.1
folate receptor 1 (adult)
chr15_+_85017138 0.27 ENSMUST00000023070.5
uroplakin 3A
chr11_+_49203465 0.27 ENSMUST00000150284.1
ENSMUST00000109197.1
ENSMUST00000151228.1
zinc finger protein 62
chr3_+_37639945 0.27 ENSMUST00000108109.1
ENSMUST00000038569.1
sprouty homolog 1 (Drosophila)
chr4_+_134468320 0.27 ENSMUST00000030636.4
ENSMUST00000127279.1
ENSMUST00000105867.1
stathmin 1
chr2_-_84727350 0.26 ENSMUST00000028475.8
CLP1, cleavage and polyadenylation factor I subunit
chr2_+_149830840 0.26 ENSMUST00000109934.1
ENSMUST00000140870.1
synapse differentiation inducing 1
chr4_-_58553311 0.26 ENSMUST00000107571.1
ENSMUST00000055018.4
lysophosphatidic acid receptor 1
chr2_+_158794807 0.26 ENSMUST00000029186.7
ENSMUST00000109478.2
ENSMUST00000156893.1
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr2_+_158028687 0.26 ENSMUST00000109518.1
ENSMUST00000029180.7
regulation of nuclear pre-mRNA domain containing 1B
chrX_+_10485121 0.25 ENSMUST00000076354.6
ENSMUST00000115526.1
tetraspanin 7
chr14_-_70443219 0.25 ENSMUST00000180358.1
polymerase (RNA) III (DNA directed) polypeptide D
chrX_+_136741821 0.25 ENSMUST00000089350.4
cDNA sequence BC065397
chr3_+_157534103 0.24 ENSMUST00000106058.1
zinc finger, RAN-binding domain containing 2
chr11_+_70432627 0.24 ENSMUST00000084954.6
ENSMUST00000108568.3
ENSMUST00000079056.2
ENSMUST00000102564.4
ENSMUST00000124943.1
ENSMUST00000150076.1
ENSMUST00000102563.1
arrestin, beta 2
chr18_+_70568189 0.24 ENSMUST00000074058.4
ENSMUST00000114946.3
methyl-CpG binding domain protein 2
chr4_+_48585135 0.24 ENSMUST00000030032.6
transmembrane protein with EGF-like and two follistatin-like domains 1
chr12_+_83950608 0.23 ENSMUST00000053744.7
RIKEN cDNA 2410016O06 gene
chr14_+_31019159 0.23 ENSMUST00000112094.1
ENSMUST00000144009.1
polybromo 1
chr2_+_158028481 0.23 ENSMUST00000103123.3
regulation of nuclear pre-mRNA domain containing 1B
chr2_+_28205648 0.23 ENSMUST00000102879.3
ENSMUST00000028177.4
olfactomedin 1
chr4_-_129742275 0.23 ENSMUST00000066257.5
KH domain containing, RNA binding, signal transduction associated 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Hes1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.5 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
2.2 24.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.9 4.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.7 2.1 GO:2000978 negative regulation of forebrain neuron differentiation(GO:2000978)
0.5 4.4 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.5 1.6 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
0.5 2.9 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.5 2.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.4 2.1 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.4 1.2 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.4 2.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.3 1.3 GO:0006014 D-ribose metabolic process(GO:0006014)
0.3 0.9 GO:2000451 immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
0.3 1.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.3 1.4 GO:0097167 circadian regulation of translation(GO:0097167)
0.2 2.0 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.2 1.0 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.2 1.9 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.2 0.8 GO:2000705 negative regulation of anion channel activity(GO:0010360) regulation of dense core granule biogenesis(GO:2000705)
0.2 0.6 GO:1990523 bone regeneration(GO:1990523)
0.2 1.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.2 1.0 GO:1904970 brush border assembly(GO:1904970)
0.2 1.5 GO:0051013 microtubule severing(GO:0051013)
0.2 1.8 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.2 2.6 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.2 0.8 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.2 7.4 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.2 0.7 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 0.5 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.2 0.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 0.5 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) positive regulation of dermatome development(GO:0061184) renal vesicle induction(GO:0072034) negative regulation of male gonad development(GO:2000019)
0.2 0.5 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 5.7 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
0.1 0.4 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 1.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 1.4 GO:0030432 peristalsis(GO:0030432)
0.1 0.9 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.5 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.1 0.7 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 2.0 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 0.8 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.5 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.3 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.1 0.6 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.4 GO:0035087 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.1 0.3 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.4 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.2 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.1 0.8 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.7 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.7 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 0.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.2 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.1 0.2 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) response to laminar fluid shear stress(GO:0034616) negative regulation of interleukin-8 biosynthetic process(GO:0045415) cellular response to laminar fluid shear stress(GO:0071499)
0.1 0.3 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 0.6 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 3.0 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.1 0.9 GO:0006415 translational termination(GO:0006415)
0.0 0.3 GO:0045585 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0 1.1 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.9 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 2.1 GO:0021591 ventricular system development(GO:0021591)
0.0 2.7 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 0.9 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 2.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.3 GO:0060157 urea transport(GO:0015840) urinary bladder development(GO:0060157)
0.0 0.8 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.3 GO:0015670 carbon dioxide transport(GO:0015670) one-carbon compound transport(GO:0019755)
0.0 0.1 GO:0072757 cellular response to camptothecin(GO:0072757)
0.0 2.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 2.6 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.0 0.2 GO:0006680 glucosylceramide catabolic process(GO:0006680) positive regulation of phospholipid catabolic process(GO:0060697)
0.0 0.1 GO:0060032 notochord regression(GO:0060032)
0.0 0.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 2.4 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.6 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.6 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.5 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.2 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 1.2 GO:0006414 translational elongation(GO:0006414)
0.0 0.1 GO:0008358 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.2 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.4 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 1.1 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.9 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.0 0.2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.3 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.4 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.6 GO:0001706 endoderm formation(GO:0001706)
0.0 0.1 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.1 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.4 GO:0009409 response to cold(GO:0009409)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.7 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.3 4.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3 7.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.3 1.6 GO:1990769 proximal neuron projection(GO:1990769)
0.3 1.7 GO:0000235 astral microtubule(GO:0000235)
0.2 0.8 GO:0099522 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.2 1.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 3.1 GO:0031143 pseudopodium(GO:0031143)
0.2 2.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 2.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.8 GO:0005638 lamin filament(GO:0005638)
0.1 1.0 GO:0070578 RISC-loading complex(GO:0070578)
0.1 1.6 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.9 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 4.3 GO:0015030 Cajal body(GO:0015030)
0.1 1.3 GO:0000124 SAGA complex(GO:0000124)
0.1 0.7 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.7 GO:0005652 nuclear lamina(GO:0005652)
0.1 0.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 1.0 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 1.4 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.1 1.4 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.7 GO:0000242 pericentriolar material(GO:0000242)
0.0 3.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.6 GO:0005682 U5 snRNP(GO:0005682)
0.0 1.1 GO:0043034 costamere(GO:0043034)
0.0 0.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.0 GO:0019034 viral replication complex(GO:0019034)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0097542 ciliary tip(GO:0097542)
0.0 2.5 GO:0008021 synaptic vesicle(GO:0008021)
0.0 2.0 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.0 GO:0043198 dendritic shaft(GO:0043198)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.3 GO:0008859 exoribonuclease II activity(GO:0008859)
1.0 3.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.7 7.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.6 1.8 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.5 4.4 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.5 5.6 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.5 24.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.4 4.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.4 2.6 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.3 2.4 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.3 0.9 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.3 0.9 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.3 1.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 0.8 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.2 0.7 GO:0035500 MH2 domain binding(GO:0035500)
0.2 0.2 GO:0031762 alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762)
0.2 0.9 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 1.6 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.2 8.5 GO:0070412 R-SMAD binding(GO:0070412)
0.2 0.7 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.2 1.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.2 0.5 GO:0035939 microsatellite binding(GO:0035939)
0.1 1.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.5 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.1 1.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.6 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.0 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.3 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.1 2.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 1.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.4 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 2.1 GO:0070840 dynein complex binding(GO:0070840)
0.1 1.6 GO:0004697 protein kinase C activity(GO:0004697)
0.1 3.4 GO:0070888 E-box binding(GO:0070888)
0.1 1.6 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.1 2.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 1.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 1.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 1.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 1.2 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0051870 methotrexate binding(GO:0051870)
0.0 3.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0035197 siRNA binding(GO:0035197)
0.0 0.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 1.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.6 GO:0019894 kinesin binding(GO:0019894)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 2.1 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 25.1 PID IGF1 PATHWAY IGF1 pathway
0.1 4.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 4.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 2.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 1.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 4.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.2 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 24.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 7.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 0.9 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 1.6 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 2.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 4.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 3.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 4.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 2.7 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 3.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 4.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 1.0 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 0.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 2.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 3.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 4.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.5 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.7 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases