Motif ID: Hic2

Z-value: 1.971


Transcription factors associated with Hic2:

Gene SymbolEntrez IDGene Name
Hic2 ENSMUSG00000050240.8 Hic2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hic2mm10_v2_chr16_+_17233560_172336640.685.7e-06Click!


Activity profile for motif Hic2.

activity profile for motif Hic2


Sorted Z-values histogram for motif Hic2

Sorted Z-values for motif Hic2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hic2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_109459843 18.916 ENSMUST00000173812.1
Dlk1
delta-like 1 homolog (Drosophila)
chr12_+_109549157 13.165 ENSMUST00000128458.1
ENSMUST00000150851.1
Meg3

maternally expressed 3

chr11_+_7197780 9.978 ENSMUST00000020704.7
Igfbp1
insulin-like growth factor binding protein 1
chr7_+_19411086 9.602 ENSMUST00000003643.1
Ckm
creatine kinase, muscle
chr11_+_87794206 9.488 ENSMUST00000121303.1
Mpo
myeloperoxidase
chr10_+_127725392 8.576 ENSMUST00000026466.3
Tac2
tachykinin 2
chr11_+_115877497 8.392 ENSMUST00000144032.1
Myo15b
myosin XVB
chr11_-_102365111 8.346 ENSMUST00000006749.9
Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr6_+_34412334 8.297 ENSMUST00000007449.8
Akr1b7
aldo-keto reductase family 1, member B7
chr14_+_51853699 8.147 ENSMUST00000169070.1
ENSMUST00000074477.6
Ear6

eosinophil-associated, ribonuclease A family, member 6

chr18_+_34840575 7.951 ENSMUST00000043484.7
Reep2
receptor accessory protein 2
chr12_+_109544498 7.881 ENSMUST00000126289.1
Meg3
maternally expressed 3
chr12_+_109453455 7.648 ENSMUST00000109844.4
ENSMUST00000109842.2
ENSMUST00000109843.1
ENSMUST00000109846.4
ENSMUST00000173539.1
ENSMUST00000109841.2
Dlk1





delta-like 1 homolog (Drosophila)





chr4_+_130055010 7.429 ENSMUST00000123617.1
Col16a1
collagen, type XVI, alpha 1
chr11_-_69617879 7.185 ENSMUST00000005334.2
Shbg
sex hormone binding globulin
chr10_-_128401218 7.102 ENSMUST00000042666.5
Slc39a5
solute carrier family 39 (metal ion transporter), member 5
chr7_-_142578093 7.099 ENSMUST00000149974.1
ENSMUST00000152754.1
H19

H19 fetal liver mRNA

chr18_-_78123324 7.072 ENSMUST00000160292.1
ENSMUST00000091813.5
Slc14a1

solute carrier family 14 (urea transporter), member 1

chr7_+_96211656 7.042 ENSMUST00000107165.1
Tenm4
teneurin transmembrane protein 4
chr12_+_109452833 6.994 ENSMUST00000056110.8
Dlk1
delta-like 1 homolog (Drosophila)
chr7_-_142578139 6.893 ENSMUST00000136359.1
H19
H19 fetal liver mRNA
chr9_-_103480328 6.740 ENSMUST00000124310.2
Bfsp2
beaded filament structural protein 2, phakinin
chr7_-_24760311 6.576 ENSMUST00000063956.5
Cd177
CD177 antigen
chr11_+_115887601 6.488 ENSMUST00000167507.2
Myo15b
myosin XVB
chr14_-_20269162 6.456 ENSMUST00000024155.7
Kcnk16
potassium channel, subfamily K, member 16
chr4_-_118457450 6.450 ENSMUST00000106375.1
ENSMUST00000006556.3
ENSMUST00000168404.1
Mpl


myeloproliferative leukemia virus oncogene


chr19_+_10015016 6.412 ENSMUST00000137637.1
ENSMUST00000149967.1
Rab3il1

RAB3A interacting protein (rabin3)-like 1

chr2_-_163918683 6.388 ENSMUST00000044734.2
Rims4
regulating synaptic membrane exocytosis 4
chr11_+_11684967 6.386 ENSMUST00000126058.1
ENSMUST00000141436.1
Ikzf1

IKAROS family zinc finger 1

chr7_+_28540863 6.316 ENSMUST00000119180.2
Sycn
syncollin
chr7_-_126414855 6.229 ENSMUST00000032968.5
Cd19
CD19 antigen
chr11_+_4236411 6.152 ENSMUST00000075221.2
Osm
oncostatin M
chr12_+_111417430 6.087 ENSMUST00000072646.6
Exoc3l4
exocyst complex component 3-like 4
chr4_-_118457509 6.071 ENSMUST00000102671.3
Mpl
myeloproliferative leukemia virus oncogene
chr8_-_10928449 6.071 ENSMUST00000040608.3
3930402G23Rik
RIKEN cDNA 3930402G23 gene
chr1_+_93006328 5.818 ENSMUST00000059676.4
Aqp12
aquaporin 12
chr7_-_110982049 5.794 ENSMUST00000142368.1
Mrvi1
MRV integration site 1
chr4_-_140774196 5.769 ENSMUST00000026381.6
Padi4
peptidyl arginine deiminase, type IV
chr9_+_58014990 5.626 ENSMUST00000034874.7
Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
chr12_+_102554966 5.509 ENSMUST00000021610.5
Chga
chromogranin A
chr17_+_25471564 5.500 ENSMUST00000025002.1
Tekt4
tektin 4
chr7_+_142498832 5.490 ENSMUST00000078497.8
ENSMUST00000105953.3
ENSMUST00000179658.1
ENSMUST00000105954.3
ENSMUST00000105952.3
ENSMUST00000105955.1
ENSMUST00000074187.6
ENSMUST00000180152.1
ENSMUST00000105950.4
ENSMUST00000105957.3
ENSMUST00000169299.2
ENSMUST00000105958.3
ENSMUST00000105949.1
Tnnt3












troponin T3, skeletal, fast












chrX_+_93675088 5.320 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr7_+_16906488 5.272 ENSMUST00000086101.5
ENSMUST00000144408.1
Ptgir

prostaglandin I receptor (IP)

chr17_-_57194170 5.235 ENSMUST00000005976.6
Tnfsf14
tumor necrosis factor (ligand) superfamily, member 14
chr6_+_29694204 5.226 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr3_+_68691424 5.208 ENSMUST00000107816.2
Il12a
interleukin 12a
chr17_-_35066170 4.962 ENSMUST00000174190.1
ENSMUST00000097337.1
AU023871

expressed sequence AU023871

chr12_+_24831583 4.910 ENSMUST00000110942.3
ENSMUST00000078902.6
Mboat2

membrane bound O-acyltransferase domain containing 2

chr9_+_45138437 4.823 ENSMUST00000060125.5
Scn4b
sodium channel, type IV, beta
chr17_+_48247759 4.817 ENSMUST00000048065.5
Trem3
triggering receptor expressed on myeloid cells 3
chr7_-_126704736 4.802 ENSMUST00000131415.1
Coro1a
coronin, actin binding protein 1A
chr12_-_79007276 4.799 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr2_-_170427828 4.778 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
Bcas1


breast carcinoma amplified sequence 1


chr15_-_79285470 4.752 ENSMUST00000170955.1
Baiap2l2
BAI1-associated protein 2-like 2
chr11_+_98383811 4.715 ENSMUST00000008021.2
Tcap
titin-cap
chr8_+_23139064 4.714 ENSMUST00000033947.8
Ank1
ankyrin 1, erythroid
chr10_+_75571522 4.674 ENSMUST00000143226.1
ENSMUST00000124259.1
Ggt1

gamma-glutamyltransferase 1

chr2_-_28563362 4.564 ENSMUST00000028161.5
Cel
carboxyl ester lipase
chr13_-_19619820 4.436 ENSMUST00000002885.6
Epdr1
ependymin related protein 1 (zebrafish)
chr10_-_19851459 4.433 ENSMUST00000059805.4
Slc35d3
solute carrier family 35, member D3
chr19_-_4615647 4.414 ENSMUST00000113822.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr11_-_120648104 4.404 ENSMUST00000026134.2
Myadml2
myeloid-associated differentiation marker-like 2
chr15_+_99224976 4.402 ENSMUST00000041415.3
Kcnh3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr15_-_79285502 4.378 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr8_+_23139030 4.355 ENSMUST00000121075.1
Ank1
ankyrin 1, erythroid
chr4_-_64046925 4.326 ENSMUST00000107377.3
Tnc
tenascin C
chr15_+_76457438 4.234 ENSMUST00000043089.7
Scx
scleraxis
chr19_-_4877882 4.232 ENSMUST00000006626.3
Actn3
actinin alpha 3
chr8_-_121907678 4.164 ENSMUST00000045557.9
Slc7a5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
chr1_-_75505641 4.160 ENSMUST00000155084.1
Obsl1
obscurin-like 1
chr11_-_46312220 4.150 ENSMUST00000129474.1
ENSMUST00000093166.4
ENSMUST00000165599.2
Cyfip2


cytoplasmic FMR1 interacting protein 2


chr7_+_110774240 4.093 ENSMUST00000147587.1
Ampd3
adenosine monophosphate deaminase 3
chr7_-_110982169 4.066 ENSMUST00000154466.1
Mrvi1
MRV integration site 1
chr5_-_107723954 4.049 ENSMUST00000165344.1
Gfi1
growth factor independent 1
chr7_+_142472080 4.048 ENSMUST00000105966.1
Lsp1
lymphocyte specific 1
chr11_+_43528759 4.008 ENSMUST00000050574.6
Ccnjl
cyclin J-like
chr17_-_24527830 3.964 ENSMUST00000176353.1
ENSMUST00000176237.1
Traf7

TNF receptor-associated factor 7

chr19_-_10203880 3.957 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chr7_+_127211608 3.938 ENSMUST00000032910.6
Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr11_+_32276400 3.912 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr17_-_8101228 3.880 ENSMUST00000097422.4
Gm1604A
predicted gene 1604A
chr7_+_110768169 3.845 ENSMUST00000170374.1
Ampd3
adenosine monophosphate deaminase 3
chr12_+_109545390 3.822 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr15_+_57985873 3.795 ENSMUST00000050374.2
Fam83a
family with sequence similarity 83, member A
chr9_+_119052770 3.787 ENSMUST00000051386.6
ENSMUST00000074734.6
Vill

villin-like

chr13_+_21722057 3.711 ENSMUST00000110476.3
Hist1h2bm
histone cluster 1, H2bm
chr17_+_35821675 3.700 ENSMUST00000003635.6
Ier3
immediate early response 3
chr9_+_8544196 3.695 ENSMUST00000050433.6
Trpc6
transient receptor potential cation channel, subfamily C, member 6
chr1_+_135132693 3.694 ENSMUST00000049449.4
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr8_+_105518736 3.677 ENSMUST00000034363.5
Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
chr11_+_97050811 3.646 ENSMUST00000168565.1
Osbpl7
oxysterol binding protein-like 7
chr3_+_108383829 3.634 ENSMUST00000090561.3
ENSMUST00000102629.1
ENSMUST00000128089.1
Psrc1


proline/serine-rich coiled-coil 1


chr7_-_135716374 3.625 ENSMUST00000033310.7
Mki67
antigen identified by monoclonal antibody Ki 67
chr8_-_46211284 3.624 ENSMUST00000034049.4
Slc25a4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr9_-_37552904 3.596 ENSMUST00000065668.5
Nrgn
neurogranin
chr9_+_119052863 3.589 ENSMUST00000131647.1
Vill
villin-like
chr7_+_19577287 3.570 ENSMUST00000108453.1
Zfp296
zinc finger protein 296
chr7_+_80294450 3.552 ENSMUST00000163812.2
ENSMUST00000047558.7
ENSMUST00000174199.1
ENSMUST00000173824.1
ENSMUST00000174172.1
Prc1




protein regulator of cytokinesis 1




chr6_-_78378851 3.520 ENSMUST00000089667.1
ENSMUST00000167492.1
Reg3d

regenerating islet-derived 3 delta

chr19_-_4615453 3.507 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr11_+_115154139 3.497 ENSMUST00000021076.5
Rab37
RAB37, member of RAS oncogene family
chr17_-_25952565 3.482 ENSMUST00000162431.1
A930017K11Rik
RIKEN cDNA A930017K11 gene
chr14_+_118854695 3.471 ENSMUST00000100314.3
Cldn10
claudin 10
chr11_+_97050594 3.451 ENSMUST00000090020.5
Osbpl7
oxysterol binding protein-like 7
chrX_-_49788204 3.443 ENSMUST00000114893.1
Igsf1
immunoglobulin superfamily, member 1
chr4_-_108383349 3.438 ENSMUST00000053157.6
Fam159a
family with sequence similarity 159, member A
chr7_-_126704816 3.407 ENSMUST00000032949.7
Coro1a
coronin, actin binding protein 1A
chr2_-_181156993 3.395 ENSMUST00000055990.7
Eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr1_+_134182150 3.389 ENSMUST00000156873.1
Chi3l1
chitinase 3-like 1
chr11_+_76998595 3.373 ENSMUST00000108402.2
ENSMUST00000021195.4
Slc6a4

solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

chr3_+_88607742 3.373 ENSMUST00000175903.1
Arhgef2
rho/rac guanine nucleotide exchange factor (GEF) 2
chr7_-_110982443 3.366 ENSMUST00000005751.6
Mrvi1
MRV integration site 1
chr5_-_53707532 3.350 ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chr17_-_24527925 3.350 ENSMUST00000176652.1
Traf7
TNF receptor-associated factor 7
chr19_+_4154606 3.287 ENSMUST00000061086.8
Ptprcap
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr7_+_110773658 3.254 ENSMUST00000143786.1
Ampd3
adenosine monophosphate deaminase 3
chr5_-_112392213 3.236 ENSMUST00000031291.7
Asphd2
aspartate beta-hydroxylase domain containing 2
chr14_-_51057242 3.190 ENSMUST00000089798.2
Rnase12
ribonuclease, RNase A family, 12 (non-active)
chr7_-_67803489 3.179 ENSMUST00000181235.1
4833412C05Rik
RIKEN cDNA 4833412C05 gene
chr19_-_34255325 3.144 ENSMUST00000039631.8
Acta2
actin, alpha 2, smooth muscle, aorta
chr10_+_79930419 3.106 ENSMUST00000131118.1
Arid3a
AT rich interactive domain 3A (BRIGHT-like)
chr12_-_113422730 3.100 ENSMUST00000177715.1
ENSMUST00000103426.1
Ighm

immunoglobulin heavy constant mu

chr17_+_28207778 3.084 ENSMUST00000002327.5
Def6
differentially expressed in FDCP 6
chr9_+_107906866 3.068 ENSMUST00000035203.7
Mst1r
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr4_-_117929466 3.059 ENSMUST00000097913.2
Artn
artemin
chr3_-_98893209 3.053 ENSMUST00000029464.7
Hao2
hydroxyacid oxidase 2
chr4_-_129440800 3.044 ENSMUST00000053042.5
ENSMUST00000106046.1
Zbtb8b

zinc finger and BTB domain containing 8b

chr1_+_134193432 3.037 ENSMUST00000038445.6
Mybph
myosin binding protein H
chr15_-_55090422 2.998 ENSMUST00000110231.1
ENSMUST00000023059.6
Dscc1

defective in sister chromatid cohesion 1 homolog (S. cerevisiae)

chrX_-_104671048 2.984 ENSMUST00000042070.5
Zdhhc15
zinc finger, DHHC domain containing 15
chr1_+_174041933 2.979 ENSMUST00000052975.4
Olfr433
olfactory receptor 433
chr12_+_85599388 2.971 ENSMUST00000050687.6
Jdp2
Jun dimerization protein 2
chr11_-_12026237 2.937 ENSMUST00000150972.1
Grb10
growth factor receptor bound protein 10
chr13_-_70841790 2.931 ENSMUST00000080145.6
ENSMUST00000109694.2
Adamts16

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16

chr7_-_103813913 2.921 ENSMUST00000098192.3
Hbb-bt
hemoglobin, beta adult t chain
chr7_+_43440782 2.915 ENSMUST00000040227.1
Cldnd2
claudin domain containing 2
chr17_-_56830916 2.912 ENSMUST00000002444.7
ENSMUST00000086801.5
Rfx2

regulatory factor X, 2 (influences HLA class II expression)

chr11_-_12026732 2.904 ENSMUST00000143915.1
Grb10
growth factor receptor bound protein 10
chrX_-_8145679 2.890 ENSMUST00000115619.1
ENSMUST00000115617.3
ENSMUST00000040010.3
Rbm3


RNA binding motif protein 3


chr11_-_106349389 2.886 ENSMUST00000021056.7
Scn4a
sodium channel, voltage-gated, type IV, alpha
chr11_-_69602741 2.879 ENSMUST00000138694.1
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr7_-_100856289 2.862 ENSMUST00000139604.1
Relt
RELT tumor necrosis factor receptor
chr11_+_69095217 2.838 ENSMUST00000101004.2
Per1
period circadian clock 1
chr11_+_115974930 2.819 ENSMUST00000106460.2
Itgb4
integrin beta 4
chrX_+_93654863 2.819 ENSMUST00000113933.2
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr2_+_29869484 2.805 ENSMUST00000047521.6
ENSMUST00000134152.1
Cercam

cerebral endothelial cell adhesion molecule

chr8_+_12915879 2.770 ENSMUST00000110876.2
ENSMUST00000110879.2
Mcf2l

mcf.2 transforming sequence-like

chr6_+_128399766 2.765 ENSMUST00000001561.5
Nrip2
nuclear receptor interacting protein 2
chr3_+_84666192 2.764 ENSMUST00000107682.1
Tmem154
transmembrane protein 154
chr3_+_123446913 2.757 ENSMUST00000029603.8
Prss12
protease, serine, 12 neurotrypsin (motopsin)
chr14_+_57524734 2.744 ENSMUST00000089494.4
Il17d
interleukin 17D
chr15_-_101712891 2.744 ENSMUST00000023709.5
Krt5
keratin 5
chr2_-_165473187 2.724 ENSMUST00000029208.8
ENSMUST00000109279.2
Slc13a3

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3

chr9_-_107985863 2.714 ENSMUST00000048568.4
Fam212a
family with sequence similarity 212, member A
chr2_-_170194033 2.714 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr2_-_92370968 2.712 ENSMUST00000176774.1
Gyltl1b
glycosyltransferase-like 1B
chr6_-_29212240 2.706 ENSMUST00000160878.1
ENSMUST00000078155.5
Impdh1

inosine 5'-phosphate dehydrogenase 1

chr9_-_119578981 2.701 ENSMUST00000117911.1
ENSMUST00000120420.1
Scn5a

sodium channel, voltage-gated, type V, alpha

chrX_-_51205990 2.673 ENSMUST00000114876.2
Mbnl3
muscleblind-like 3 (Drosophila)
chr1_-_75506331 2.642 ENSMUST00000113567.2
ENSMUST00000113565.2
Obsl1

obscurin-like 1

chr7_+_28982832 2.626 ENSMUST00000085835.6
Map4k1
mitogen-activated protein kinase kinase kinase kinase 1
chr17_-_32403551 2.620 ENSMUST00000135618.1
ENSMUST00000063824.7
Rasal3

RAS protein activator like 3

chr4_-_127330799 2.614 ENSMUST00000046532.3
Gjb3
gap junction protein, beta 3
chr10_-_61273242 2.610 ENSMUST00000120336.1
Adamts14
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 14
chr6_+_128399881 2.598 ENSMUST00000120405.1
Nrip2
nuclear receptor interacting protein 2
chr13_-_3804307 2.589 ENSMUST00000077698.3
Calml3
calmodulin-like 3
chr2_+_130277157 2.576 ENSMUST00000028890.8
ENSMUST00000159373.1
Nop56

NOP56 ribonucleoprotein

chr2_+_92915080 2.562 ENSMUST00000028648.2
Syt13
synaptotagmin XIII
chr4_+_154960915 2.555 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr14_+_60378242 2.527 ENSMUST00000022561.6
Amer2
APC membrane recruitment 2
chr2_-_33887862 2.526 ENSMUST00000041555.3
Mvb12b
multivesicular body subunit 12B
chr2_-_29869785 2.520 ENSMUST00000047607.1
2600006K01Rik
RIKEN cDNA 2600006K01 gene
chr17_-_32403526 2.512 ENSMUST00000137458.1
Rasal3
RAS protein activator like 3
chr3_-_153725062 2.510 ENSMUST00000064460.5
St6galnac3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr15_-_66831625 2.486 ENSMUST00000164163.1
Sla
src-like adaptor
chrX_+_74329058 2.475 ENSMUST00000004326.3
Plxna3
plexin A3
chr4_-_152477433 2.455 ENSMUST00000159186.1
ENSMUST00000162017.1
ENSMUST00000030768.2
Kcnab2


potassium voltage-gated channel, shaker-related subfamily, beta member 2


chr2_-_92370999 2.449 ENSMUST00000176810.1
ENSMUST00000090582.4
Gyltl1b

glycosyltransferase-like 1B

chr11_+_96931387 2.448 ENSMUST00000107633.1
Prr15l
proline rich 15-like
chr17_-_25433775 2.442 ENSMUST00000159610.1
ENSMUST00000159048.1
ENSMUST00000078496.5
Cacna1h


calcium channel, voltage-dependent, T type, alpha 1H subunit


chr11_-_102897123 2.439 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr2_-_166713758 2.437 ENSMUST00000036719.5
Prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr11_+_87755567 2.435 ENSMUST00000123700.1
A430104N18Rik
RIKEN cDNA A430104N18 gene
chr13_+_20090538 2.421 ENSMUST00000072519.5
Elmo1
engulfment and cell motility 1
chr5_+_30666886 2.419 ENSMUST00000144742.1
Cenpa
centromere protein A
chr2_+_106695594 2.418 ENSMUST00000016530.7
Mpped2
metallophosphoesterase domain containing 2
chr17_-_48409729 2.383 ENSMUST00000160319.1
ENSMUST00000159535.1
ENSMUST00000078800.6
ENSMUST00000046719.7
ENSMUST00000162460.1
Nfya




nuclear transcription factor-Y alpha




chr4_+_133240778 2.362 ENSMUST00000030677.6
Map3k6
mitogen-activated protein kinase kinase kinase 6
chr8_-_85380964 2.357 ENSMUST00000122452.1
Mylk3
myosin light chain kinase 3
chr15_-_98607611 2.355 ENSMUST00000096224.4
Adcy6
adenylate cyclase 6
chr4_-_134128707 2.352 ENSMUST00000105879.1
ENSMUST00000030651.8
Sh3bgrl3

SH3 domain binding glutamic acid-rich protein-like 3

chr19_-_46044914 2.323 ENSMUST00000026252.7
Ldb1
LIM domain binding 1
chr18_+_62180119 2.319 ENSMUST00000067743.1
Gm9949
predicted gene 9949
chr10_-_80421847 2.316 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr4_+_140906344 2.308 ENSMUST00000030765.6
Padi2
peptidyl arginine deiminase, type II
chrX_+_134308084 2.300 ENSMUST00000081064.5
ENSMUST00000101251.1
ENSMUST00000129782.1
Cenpi


centromere protein I


chr12_+_110279228 2.298 ENSMUST00000097228.4
Dio3
deiodinase, iodothyronine type III
chr18_-_62179948 2.296 ENSMUST00000053640.3
Adrb2
adrenergic receptor, beta 2
chr4_+_136284708 2.290 ENSMUST00000130223.1
Zfp46
zinc finger protein 46

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 11.9 GO:0035702 monocyte homeostasis(GO:0035702)
3.2 9.5 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
2.4 7.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
2.1 6.4 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
1.8 5.5 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
1.8 9.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
1.7 5.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
1.7 5.2 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
1.7 10.2 GO:0032796 uropod organization(GO:0032796)
1.5 5.9 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
1.4 7.0 GO:0032289 central nervous system myelin formation(GO:0032289)
1.3 11.3 GO:0032264 IMP salvage(GO:0032264)
1.2 3.7 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
1.2 6.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
1.2 8.6 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
1.2 11.5 GO:0051133 regulation of NK T cell activation(GO:0051133)
1.2 3.5 GO:0002017 regulation of blood volume by renal aldosterone(GO:0002017)
1.1 2.3 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
1.1 8.0 GO:0032596 protein transport into membrane raft(GO:0032596)
1.1 3.4 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
1.1 2.2 GO:2000978 negative regulation of forebrain neuron differentiation(GO:2000978)
1.1 4.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
1.1 4.3 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.1 14.0 GO:2000653 regulation of genetic imprinting(GO:2000653)
1.1 1.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
1.0 3.1 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
1.0 30.9 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
1.0 4.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
1.0 1.0 GO:0001698 gastrin-induced gastric acid secretion(GO:0001698)
1.0 7.1 GO:0071918 urea transmembrane transport(GO:0071918)
1.0 5.9 GO:0000160 phosphorelay signal transduction system(GO:0000160)
1.0 1.0 GO:0060983 epicardium-derived cardiac vascular smooth muscle cell differentiation(GO:0060983)
1.0 2.9 GO:1990705 cholangiocyte proliferation(GO:1990705)
1.0 2.9 GO:0046436 D-serine catabolic process(GO:0036088) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.9 12.8 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.9 14.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.9 3.6 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.9 0.9 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.9 0.9 GO:0042223 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.9 6.1 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.8 4.2 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.8 3.4 GO:0060032 notochord regression(GO:0060032)
0.8 3.4 GO:0021941 negative regulation of cerebellar granule cell precursor proliferation(GO:0021941)
0.8 1.7 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.8 24.5 GO:0008340 determination of adult lifespan(GO:0008340)
0.8 1.6 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.8 5.5 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.8 3.1 GO:1903116 positive regulation of actin filament-based movement(GO:1903116)
0.7 2.2 GO:0045004 DNA replication proofreading(GO:0045004)
0.7 2.2 GO:0070375 ERK5 cascade(GO:0070375)
0.7 1.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.7 2.9 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.7 7.1 GO:0071397 cellular response to cholesterol(GO:0071397)
0.7 2.7 GO:0015744 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
0.7 3.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.7 4.0 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.7 2.0 GO:0070649 formin-nucleated actin cable assembly(GO:0070649) formin-nucleated actin cable organization(GO:0110009)
0.7 2.0 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.6 1.9 GO:1990523 bone regeneration(GO:1990523)
0.6 3.2 GO:0072236 metanephric loop of Henle development(GO:0072236)
0.6 3.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.6 2.4 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.6 3.0 GO:0050915 sensory perception of sour taste(GO:0050915)
0.6 2.4 GO:0048769 sarcomerogenesis(GO:0048769)
0.6 1.8 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.6 4.7 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.6 1.7 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.6 2.3 GO:1904504 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure(GO:0002025) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.6 2.8 GO:0097167 circadian regulation of translation(GO:0097167)
0.6 1.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.6 2.8 GO:0034421 post-translational protein acetylation(GO:0034421)
0.6 2.8 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.6 2.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.6 1.7 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.5 2.7 GO:0006177 GMP biosynthetic process(GO:0006177)
0.5 1.6 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.5 1.6 GO:0021570 rhombomere 4 development(GO:0021570)
0.5 1.6 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.5 5.8 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.5 2.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.5 2.0 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.5 1.5 GO:0061076 camera-type eye photoreceptor cell fate commitment(GO:0060220) negative regulation of neural retina development(GO:0061076) negative regulation of retina development in camera-type eye(GO:1902867) negative regulation of amacrine cell differentiation(GO:1902870)
0.5 1.0 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.5 1.0 GO:0015793 glycerol transport(GO:0015793) cellular response to mercury ion(GO:0071288)
0.5 2.0 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.5 1.5 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.5 1.5 GO:0006714 sesquiterpenoid metabolic process(GO:0006714)
0.5 2.0 GO:0021586 pons maturation(GO:0021586)
0.5 4.4 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.5 1.0 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.5 3.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.5 1.4 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.5 7.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.5 0.9 GO:0072053 renal inner medulla development(GO:0072053)
0.5 1.4 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.4 2.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.4 3.5 GO:0061789 dense core granule priming(GO:0061789)
0.4 1.8 GO:0010040 response to iron(II) ion(GO:0010040)
0.4 1.3 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.4 2.6 GO:0003091 renal water homeostasis(GO:0003091)
0.4 3.4 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.4 4.6 GO:0035878 nail development(GO:0035878)
0.4 2.1 GO:0035993 subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) superior vena cava morphogenesis(GO:0060578)
0.4 2.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.4 1.6 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.4 2.0 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.4 0.8 GO:0021558 trochlear nerve development(GO:0021558)
0.4 6.7 GO:0070307 lens fiber cell development(GO:0070307)
0.4 4.4 GO:0015871 choline transport(GO:0015871)
0.4 1.6 GO:0061743 motor learning(GO:0061743)
0.4 9.0 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.4 1.6 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.4 9.8 GO:0033622 integrin activation(GO:0033622)
0.4 2.0 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.4 1.2 GO:0042414 epinephrine metabolic process(GO:0042414)
0.4 0.4 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.4 2.3 GO:0002326 B cell lineage commitment(GO:0002326)
0.4 10.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.4 2.3 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.4 1.1 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.4 1.9 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.4 1.5 GO:1901525 negative regulation of mitophagy(GO:1901525)
0.4 2.2 GO:0061436 establishment of skin barrier(GO:0061436)
0.4 0.7 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.4 1.1 GO:0009826 unidimensional cell growth(GO:0009826)
0.4 1.8 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.4 1.8 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.4 5.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.4 4.6 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 2.1 GO:1902287 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.3 0.7 GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586)
0.3 1.0 GO:0030210 heparin biosynthetic process(GO:0030210)
0.3 2.0 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.3 2.0 GO:0030913 paranodal junction assembly(GO:0030913)
0.3 1.0 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.3 0.7 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.3 1.0 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.3 3.9 GO:0043249 erythrocyte maturation(GO:0043249)
0.3 1.3 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.3 3.5 GO:0060346 bone trabecula formation(GO:0060346)
0.3 0.6 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.3 1.3 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.3 5.1 GO:0051601 exocyst localization(GO:0051601)
0.3 2.5 GO:1900451 positive regulation of glutamate receptor signaling pathway(GO:1900451)
0.3 5.6 GO:0006968 cellular defense response(GO:0006968)
0.3 5.3 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.3 1.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3 2.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.3 0.3 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.3 8.3 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.3 1.5 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.3 4.1 GO:0001778 plasma membrane repair(GO:0001778)
0.3 1.8 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.3 5.5 GO:0099625 ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.3 0.6 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.3 0.9 GO:2000642 negative regulation of cytoplasmic transport(GO:1903650) negative regulation of early endosome to late endosome transport(GO:2000642)
0.3 0.8 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.3 0.8 GO:0072720 response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
0.3 10.1 GO:0048821 erythrocyte development(GO:0048821)
0.3 2.2 GO:0034650 cortisol metabolic process(GO:0034650) cortisol biosynthetic process(GO:0034651)
0.3 1.4 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) regulation of neurotrophin production(GO:0032899) positive regulation of neurotrophin production(GO:0032901)
0.3 1.1 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.3 5.1 GO:0003085 negative regulation of systemic arterial blood pressure(GO:0003085)
0.3 0.8 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.3 0.8 GO:0061792 secretory granule maturation(GO:0061792)
0.3 5.8 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.3 1.3 GO:0007386 compartment pattern specification(GO:0007386)
0.3 1.3 GO:1904958 positive regulation of dopaminergic neuron differentiation(GO:1904340) positive regulation of midbrain dopaminergic neuron differentiation(GO:1904958) regulation of Wnt-mediated midbrain dopaminergic neuron differentiation(GO:1905424) positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation(GO:1905426)
0.3 3.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.3 1.0 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.3 2.0 GO:1902262 apoptotic process involved in blood vessel morphogenesis(GO:1902262)
0.2 0.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2 2.0 GO:0048102 autophagic cell death(GO:0048102)
0.2 0.7 GO:0051542 elastin biosynthetic process(GO:0051542)
0.2 0.7 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.2 4.6 GO:0001675 acrosome assembly(GO:0001675)
0.2 0.5 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.2 1.9 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 1.2 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.2 0.7 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.2 1.2 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.2 1.7 GO:0090527 actin filament reorganization(GO:0090527)
0.2 0.5 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.2 0.9 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 4.7 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.2 1.4 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 0.7 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 2.3 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.2 3.9 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.2 0.5 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.2 1.8 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.2 0.7 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.2 0.9 GO:1903897 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) regulation of PERK-mediated unfolded protein response(GO:1903897) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.2 0.9 GO:0048859 formation of anatomical boundary(GO:0048859)
0.2 0.9 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.2 6.4 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.2 1.3 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.2 3.7 GO:0060263 regulation of respiratory burst(GO:0060263)
0.2 0.9 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.2 3.0 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.2 2.5 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.2 0.8 GO:0060956 endocardial cell differentiation(GO:0060956)
0.2 1.5 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.2 0.6 GO:0046104 thymidine metabolic process(GO:0046104)
0.2 1.2 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.2 1.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 0.4 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.2 0.6 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.2 4.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 0.4 GO:0006550 isoleucine catabolic process(GO:0006550)
0.2 1.3 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.2 0.6 GO:0106004 tRNA (guanine-N7)-methylation(GO:0106004)
0.2 0.7 GO:0009816 defense response, incompatible interaction(GO:0009814) defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.2 1.3 GO:0016266 O-glycan processing(GO:0016266)
0.2 0.5 GO:0006597 spermine biosynthetic process(GO:0006597)
0.2 1.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.2 0.5 GO:0099541 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.2 1.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.3 GO:0060033 anatomical structure regression(GO:0060033)
0.2 2.8 GO:2000311 regulation of AMPA receptor activity(GO:2000311)
0.2 7.1 GO:0042398 cellular modified amino acid biosynthetic process(GO:0042398)
0.2 1.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 1.0 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of JNK cascade(GO:0046329) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.2 3.1 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.2 2.4 GO:0051382 kinetochore assembly(GO:0051382)
0.2 0.5 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.2 8.2 GO:0051693 actin filament capping(GO:0051693)
0.2 0.5 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.2 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.2 0.8 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.2 0.8 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 0.7 GO:0032417 olfactory learning(GO:0008355) positive regulation of sodium:proton antiporter activity(GO:0032417)
0.2 2.3 GO:0046710 GDP metabolic process(GO:0046710)
0.2 0.8 GO:0048496 maintenance of animal organ identity(GO:0048496)
0.2 1.7 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 0.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 0.9 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.1 0.7 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 1.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 2.3 GO:0034508 centromere complex assembly(GO:0034508)
0.1 1.9 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.7 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.6 GO:1990743 protein sialylation(GO:1990743)
0.1 0.7 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.4 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.1 0.4 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.8 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) inosine biosynthetic process(GO:0046103)
0.1 1.8 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.5 GO:0030576 Cajal body organization(GO:0030576)
0.1 4.9 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 1.7 GO:0001553 luteinization(GO:0001553)
0.1 1.7 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.5 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1 0.4 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.8 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 1.4 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.1 0.6 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 1.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 1.6 GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.1 0.7 GO:0018094 protein polyglycylation(GO:0018094)
0.1 1.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 1.2 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.1 2.7 GO:0090218 positive regulation of lipid kinase activity(GO:0090218)
0.1 1.2 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 5.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 4.9 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.1 2.1 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion(GO:0010881)
0.1 0.4 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 3.5 GO:0097503 sialylation(GO:0097503)
0.1 1.4 GO:0055075 potassium ion homeostasis(GO:0055075)
0.1 0.7 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 2.7 GO:0042537 benzene-containing compound metabolic process(GO:0042537)
0.1 1.9 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.8 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.9 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 4.1 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.9 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.4 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.5 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.3 GO:0019043 establishment of viral latency(GO:0019043)
0.1 1.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.9 GO:0061626 neural crest cell migration involved in heart formation(GO:0003147) pharyngeal arch artery morphogenesis(GO:0061626) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 0.5 GO:0090083 inclusion body assembly(GO:0070841) regulation of inclusion body assembly(GO:0090083)
0.1 1.1 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 1.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 1.5 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.8 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.1 0.5 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.1 3.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.1 0.6 GO:2001170 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181) negative regulation of ATP biosynthetic process(GO:2001170)
0.1 3.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 1.0 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 0.5 GO:0035405 histone-threonine phosphorylation(GO:0035405) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 1.3 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 0.2 GO:0015819 lysine transport(GO:0015819)
0.1 0.7 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 1.2 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 1.0 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 1.0 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 0.2 GO:1903978 regulation of microglial cell activation(GO:1903978)
0.1 0.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.4 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.8 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 0.9 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.1 2.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.2 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.1 0.2 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.1 1.3 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 0.8 GO:1904867 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.1 2.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 1.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.4 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.2 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.1 0.7 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.7 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1 0.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 1.0 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.1 0.3 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 0.7 GO:0030834 regulation of actin filament depolymerization(GO:0030834)
0.1 0.6 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 3.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.3 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.1 0.5 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 2.2 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.1 0.9 GO:0015747 urate transport(GO:0015747)
0.1 0.8 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 1.0 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.7 GO:0018065 protein-cofactor linkage(GO:0018065)
0.1 0.9 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.2 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.2 GO:2000785 regulation of vacuole organization(GO:0044088) regulation of autophagosome assembly(GO:2000785)
0.1 1.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.5 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 0.2 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.1 1.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.8 GO:0070633 transepithelial transport(GO:0070633)
0.1 1.1 GO:0045109 intermediate filament organization(GO:0045109)
0.1 1.9 GO:0000154 rRNA modification(GO:0000154)
0.1 0.6 GO:0097500 receptor localization to non-motile cilium(GO:0097500)
0.1 2.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 1.4 GO:0007617 mating behavior(GO:0007617)
0.1 0.3 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 5.0 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.1 0.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.7 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.1 1.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.8 GO:0031268 pseudopodium organization(GO:0031268)
0.1 0.6 GO:2001197 regulation of basement membrane organization(GO:0110011) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 0.3 GO:0035617 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 1.5 GO:0019236 response to pheromone(GO:0019236)
0.1 0.9 GO:0099612 protein localization to axon(GO:0099612)
0.0 1.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.2 GO:0010107 potassium ion import(GO:0010107)
0.0 1.0 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.6 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 2.4 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 1.7 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.7 GO:0060998 regulation of dendritic spine development(GO:0060998)
0.0 7.4 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.0 1.2 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.5 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 2.1 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.1 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.0 0.1 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.0 0.7 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.1 GO:1905664 regulation of calcium ion import across plasma membrane(GO:1905664)
0.0 0.7 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.8 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.8 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.7 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.2 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.3 GO:0050879 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.0 1.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.5 GO:1901016 regulation of potassium ion transmembrane transporter activity(GO:1901016)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 3.2 GO:0000910 cytokinesis(GO:0000910)
0.0 0.1 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.0 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.8 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.5 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:2000786 positive regulation of vacuole organization(GO:0044090) positive regulation of autophagosome assembly(GO:2000786)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 1.0 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.0 GO:0045576 mast cell activation(GO:0045576)
0.0 0.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.4 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.2 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0000429 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite activation of transcription(GO:0045991) positive regulation of transcription by glucose(GO:0046016)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 1.5 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.0 0.1 GO:0061360 optic nerve formation(GO:0021634) regulation of metanephros size(GO:0035566) optic chiasma development(GO:0061360) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597)
0.0 0.7 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.6 GO:0090102 cochlea development(GO:0090102)
0.0 0.5 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.3 GO:0030317 flagellated sperm motility(GO:0030317)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.4 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.6 GO:2000648 positive regulation of stem cell proliferation(GO:2000648)
0.0 1.8 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.3 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.1 GO:0044819 mitotic G1 DNA damage checkpoint(GO:0031571) mitotic G1/S transition checkpoint(GO:0044819)
0.0 0.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0 0.1 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.1 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0060290 transdifferentiation(GO:0060290)
0.0 0.5 GO:0007566 embryo implantation(GO:0007566)
0.0 0.0 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.4 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 1.0 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 0.2 GO:0030252 growth hormone secretion(GO:0030252)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.6 GO:0097450 astrocyte end-foot(GO:0097450)
1.1 5.5 GO:0042583 chromaffin granule(GO:0042583)
0.9 6.8 GO:0005833 hemoglobin complex(GO:0005833)
0.8 2.4 GO:0005607 laminin-2 complex(GO:0005607)
0.8 9.1 GO:0071439 clathrin complex(GO:0071439)
0.7 10.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.7 2.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.6 2.4 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.6 15.8 GO:0005859 muscle myosin complex(GO:0005859)
0.6 3.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.6 6.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.5 2.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.5 8.5 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.5 2.1 GO:0120001 apical plasma membrane urothelial plaque(GO:0120001)
0.5 3.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.5 2.1 GO:0031094 platelet dense tubular network(GO:0031094)
0.5 1.0 GO:1990812 growth cone filopodium(GO:1990812)
0.5 1.5 GO:1905286 serine-type peptidase complex(GO:1905286)
0.4 3.1 GO:0019815 B cell receptor complex(GO:0019815)
0.4 2.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.4 10.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.4 6.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.4 2.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.4 1.5 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.4 2.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.4 1.4 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.4 10.4 GO:0001891 phagocytic cup(GO:0001891)
0.4 6.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.4 1.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.3 1.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 3.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.3 3.0 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.3 3.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 1.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.3 5.6 GO:0030061 mitochondrial crista(GO:0030061)
0.3 1.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.3 5.5 GO:0005861 troponin complex(GO:0005861)
0.3 1.5 GO:0071914 prominosome(GO:0071914)
0.3 1.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.3 3.6 GO:0044327 dendritic spine head(GO:0044327)
0.3 4.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 6.3 GO:0000145 exocyst(GO:0000145)
0.2 0.7 GO:0030934 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.2 6.1 GO:0042588 zymogen granule(GO:0042588)
0.2 3.6 GO:0070938 contractile ring(GO:0070938)
0.2 4.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 1.8 GO:0061689 tricellular tight junction(GO:0061689)
0.2 1.6 GO:0032584 growth cone membrane(GO:0032584)
0.2 3.7 GO:0031143 pseudopodium(GO:0031143)
0.2 5.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 2.8 GO:0097542 ciliary tip(GO:0097542)
0.2 0.8 GO:1990696 USH2 complex(GO:1990696)
0.2 2.8 GO:0043083 synaptic cleft(GO:0043083)
0.2 14.7 GO:0005844 polysome(GO:0005844)
0.2 0.7 GO:0032280 symmetric synapse(GO:0032280)
0.2 0.9 GO:1990769 proximal neuron projection(GO:1990769)
0.2 13.8 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.2 1.6 GO:0000813 ESCRT I complex(GO:0000813)
0.2 3.2 GO:0005922 connexin complex(GO:0005922)
0.2 1.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009) pigment granule membrane(GO:0090741)
0.2 5.1 GO:0097228 sperm principal piece(GO:0097228)
0.2 0.8 GO:0097513 myosin II filament(GO:0097513)
0.2 4.2 GO:0005865 striated muscle thin filament(GO:0005865)
0.2 1.1 GO:0005638 lamin filament(GO:0005638)
0.1 1.8 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 10.4 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.4 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 2.0 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.9 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.1 GO:0001740 Barr body(GO:0001740)
0.1 0.8 GO:0030315 T-tubule(GO:0030315)
0.1 4.1 GO:0045095 keratin filament(GO:0045095)
0.1 3.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 4.5 GO:0002102 podosome(GO:0002102)
0.1 1.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.7 GO:0031201 SNARE complex(GO:0031201)
0.1 2.2 GO:0034703 cation channel complex(GO:0034703)
0.1 0.7 GO:0030870 Mre11 complex(GO:0030870)
0.1 2.0 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 5.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.5 GO:0008537 proteasome activator complex(GO:0008537)
0.1 2.6 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 2.3 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.6 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 2.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 1.2 GO:0001939 female pronucleus(GO:0001939)
0.1 1.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 2.4 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.2 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.1 37.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.6 GO:0001527 microfibril(GO:0001527)
0.1 4.2 GO:0016459 myosin complex(GO:0016459)
0.1 2.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 6.2 GO:0005882 intermediate filament(GO:0005882)
0.1 8.8 GO:0030018 Z disc(GO:0030018)
0.1 0.3 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 6.5 GO:0000786 nucleosome(GO:0000786)
0.1 1.3 GO:0097470 ribbon synapse(GO:0097470) synaptic ribbon(GO:0098681)
0.1 4.6 GO:0005876 spindle microtubule(GO:0005876)
0.1 27.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 1.6 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.7 GO:0034709 methylosome(GO:0034709)
0.1 1.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 3.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 1.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 10.4 GO:0005903 brush border(GO:0005903)
0.1 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 2.8 GO:0042629 mast cell granule(GO:0042629)
0.1 1.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.3 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.7 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.8 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 1.2 GO:0048786 presynaptic active zone(GO:0048786)
0.1 2.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.4 GO:0097422 tubular endosome(GO:0097422)
0.1 0.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 0.4 GO:0042382 paraspeckles(GO:0042382)
0.1 0.2 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.1 1.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.2 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 4.7 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 6.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.4 GO:0031415 NatA complex(GO:0031415)
0.0 0.7 GO:0043235 receptor complex(GO:0043235)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 1.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.8 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 5.0 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0000346 transcription export complex(GO:0000346)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 4.6 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 3.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 7.9 GO:0009986 cell surface(GO:0009986)
0.0 2.7 GO:0000922 spindle pole(GO:0000922)
0.0 4.0 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 0.9 GO:0097440 apical dendrite(GO:0097440)
0.0 1.8 GO:0005643 nuclear pore(GO:0005643)
0.0 1.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.3 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.5 GO:0016592 mediator complex(GO:0016592) core mediator complex(GO:0070847)
0.0 1.2 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.8 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.1 GO:0005819 spindle(GO:0005819)
0.0 0.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 1.6 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 2.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0045120 pronucleus(GO:0045120)
0.0 0.3 GO:0001533 cornified envelope(GO:0001533)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 2.2 GO:0070401 NADP+ binding(GO:0070401)
1.8 9.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
1.8 5.3 GO:0016501 prostacyclin receptor activity(GO:0016501)
1.7 5.2 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
1.7 5.2 GO:0019972 interleukin-12 binding(GO:0019972)
1.6 8.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
1.6 9.6 GO:0004111 creatine kinase activity(GO:0004111)
1.5 4.6 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
1.3 11.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.2 3.7 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.2 3.6 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
1.2 7.1 GO:0015265 urea channel activity(GO:0015265)
1.1 10.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
1.1 3.4 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
1.1 7.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.0 10.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.0 5.9 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.9 4.7 GO:0051373 FATZ binding(GO:0051373)
0.9 2.7 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.8 3.3 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.8 4.0 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.8 5.5 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.8 3.9 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.8 3.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.8 2.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.8 3.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.8 4.6 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.7 2.9 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.7 2.9 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.7 2.1 GO:0032190 acrosin binding(GO:0032190)
0.7 2.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.7 0.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.7 9.2 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.6 1.9 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.6 2.5 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.6 2.5 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.6 4.7 GO:0002951 leukotriene-C(4) hydrolase(GO:0002951)
0.6 2.3 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.6 4.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.6 5.0 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.5 5.4 GO:0004498 calcidiol 1-monooxygenase activity(GO:0004498)
0.5 4.3 GO:0045545 syndecan binding(GO:0045545)
0.5 5.4 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.5 1.6 GO:0004947 bradykinin receptor activity(GO:0004947)
0.5 9.8 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.5 2.0 GO:0099103 channel activator activity(GO:0099103) potassium channel activator activity(GO:0099104)
0.5 9.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.5 1.5 GO:0004461 lactose synthase activity(GO:0004461)
0.5 4.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.5 5.7 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.5 1.9 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.5 1.4 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.5 2.8 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.4 8.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.4 0.9 GO:0019767 IgE receptor activity(GO:0019767)
0.4 1.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4 1.7 GO:0002046 opsin binding(GO:0002046)
0.4 4.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.4 3.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.4 1.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.4 2.4 GO:0008422 beta-glucosidase activity(GO:0008422)
0.4 2.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.4 1.6 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.4 2.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.4 3.4 GO:0034711 inhibin binding(GO:0034711)
0.4 1.1 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.4 1.9 GO:0004994 somatostatin receptor activity(GO:0004994)
0.4 1.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.4 1.5 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.3 1.4 GO:2001069 glycogen binding(GO:2001069)
0.3 1.7 GO:0042610 CD8 receptor binding(GO:0042610)
0.3 2.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.3 5.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.3 1.3 GO:0015057 thrombin-activated receptor activity(GO:0015057)
0.3 2.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.3 1.6 GO:1904288 BAT3 complex binding(GO:1904288)
0.3 2.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 2.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.3 3.4 GO:0030274 LIM domain binding(GO:0030274)
0.3 2.8 GO:1990948 ubiquitin ligase inhibitor activity(GO:1990948)
0.3 0.9 GO:0019002 GMP binding(GO:0019002)
0.3 1.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.3 1.5 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.3 0.8 GO:0004967 glucagon receptor activity(GO:0004967)
0.3 1.7 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.3 2.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.3 1.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3 3.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 1.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 3.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.3 1.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.3 1.8 GO:0019864 IgG binding(GO:0019864)
0.3 5.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.3 1.0 GO:0015054 gastrin receptor activity(GO:0015054)
0.2 13.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 0.7 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.2 5.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 1.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 1.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300) D-glucose transmembrane transporter activity(GO:0055056)
0.2 0.7 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 1.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 0.7 GO:0030226 aminophospholipid transporter activity(GO:0015247) apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 0.7 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.2 0.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 1.8 GO:0033691 sialic acid binding(GO:0033691)
0.2 4.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 0.4 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 2.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 2.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 1.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 6.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 1.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.2 1.4 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.2 1.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 6.4 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.2 6.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 1.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.2 0.8 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 0.6 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.2 8.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 2.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 1.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 0.5 GO:0070122 isopeptidase activity(GO:0070122)
0.2 1.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 0.5 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.2 1.0 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.2 1.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 2.5 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.2 1.0 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 2.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 0.5 GO:0030519 snoRNP binding(GO:0030519)
0.2 0.5 GO:0009041 uridylate kinase activity(GO:0009041)
0.2 7.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 3.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 1.1 GO:0001515 opioid peptide activity(GO:0001515)
0.2 0.6 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.2 0.6 GO:0102490 8-oxo-dGTP phosphohydrolase activity(GO:0102490)
0.2 1.5 GO:0071253 connexin binding(GO:0071253)
0.2 1.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.2 1.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 1.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.8 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.8 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 1.8 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 2.0 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.8 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.4 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 1.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.8 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.0 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.9 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.7 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 3.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 2.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 2.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.5 GO:0070976 TIR domain binding(GO:0070976)
0.1 1.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.6 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 1.2 GO:0043495 protein membrane anchor(GO:0043495)
0.1 2.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.1 7.2 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.9 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.4 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.6 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.4 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 1.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 2.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 0.5 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 2.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.7 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 1.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 2.4 GO:0031489 myosin V binding(GO:0031489)
0.1 1.1 GO:0016918 retinal binding(GO:0016918)
0.1 4.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.8 GO:0051525 NFAT protein binding(GO:0051525)
0.1 3.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.6 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 4.8 GO:0004601 peroxidase activity(GO:0004601)
0.1 1.9 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 1.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.5 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 1.4 GO:0070628 proteasome binding(GO:0070628)
0.1 1.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.4 GO:0046812 host cell surface binding(GO:0046812)
0.1 7.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.3 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 4.3 GO:0019894 kinesin binding(GO:0019894)
0.1 3.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 2.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 2.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.7 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.7 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 3.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.1 0.7 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 0.5 GO:0001595 angiotensin receptor activity(GO:0001595)
0.1 0.6 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 3.4 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 4.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.4 GO:0005113 patched binding(GO:0005113)
0.1 0.4 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.2 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 7.7 GO:0004540 ribonuclease activity(GO:0004540)
0.1 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 2.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 3.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 2.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.0 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 0.6 GO:0050897 cobalt ion binding(GO:0050897)
0.1 0.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 1.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.3 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 33.1 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.0 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.2 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.8 GO:0005123 death receptor binding(GO:0005123)
0.0 2.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 4.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.8 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.7 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.2 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 1.7 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 1.8 GO:0005518 collagen binding(GO:0005518)
0.0 1.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 1.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.9 GO:0097718 disordered domain specific binding(GO:0097718)
0.0 1.6 GO:0005496 steroid binding(GO:0005496)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 2.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 1.9 GO:0140034 methylated histone binding(GO:0035064) methylation-dependent protein binding(GO:0140034)
0.0 2.6 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.5 GO:0019955 cytokine binding(GO:0019955)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0004935 adrenergic receptor activity(GO:0004935)
0.0 4.8 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.2 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 4.2 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.8 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.8 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 39.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.5 6.6 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.4 2.0 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.3 4.9 PID_IL27_PATHWAY IL27-mediated signaling events
0.3 6.4 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.3 10.9 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.3 3.8 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 9.7 PID_IL23_PATHWAY IL23-mediated signaling events
0.2 3.9 PID_EPO_PATHWAY EPO signaling pathway
0.2 8.4 PID_IGF1_PATHWAY IGF1 pathway
0.2 7.5 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.2 8.6 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.2 5.1 PID_IL3_PATHWAY IL3-mediated signaling events
0.2 5.6 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.2 2.2 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.2 6.1 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.2 9.3 NABA_COLLAGENS Genes encoding collagen proteins
0.2 2.8 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 3.7 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.1 11.1 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 2.4 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 7.0 PID_PLK1_PATHWAY PLK1 signaling events
0.1 2.2 PID_ARF6_PATHWAY Arf6 signaling events
0.1 6.0 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.1 6.2 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 2.8 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.4 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 3.4 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 8.1 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.1 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 1.5 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 4.3 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 1.4 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.1 0.7 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 2.0 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 4.0 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 0.7 PID_ENDOTHELIN_PATHWAY Endothelins
0.1 0.7 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.1 2.4 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.1 0.7 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.1 0.4 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.1 2.0 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.6 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.1 1.2 SIG_CHEMOTAXIS Genes related to chemotaxis
0.1 1.3 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 0.7 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 1.5 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.1 0.9 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 0.5 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.0 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.0 1.2 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.6 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.9 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.3 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.7 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.6 PID_IFNG_PATHWAY IFN-gamma pathway
0.0 2.2 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.8 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.6 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.3 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.5 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.9 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.7 PID_ATM_PATHWAY ATM pathway
0.0 0.3 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 4.6 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.4 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.3 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.2 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 PID_MYC_PATHWAY C-MYC pathway
0.0 0.3 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.4 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.2 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.5 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.5 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.2 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 33.5 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.6 1.8 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.5 11.8 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.4 5.3 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.4 4.8 REACTOME_PROSTANOID_LIGAND_RECEPTORS Genes involved in Prostanoid ligand receptors
0.4 14.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.3 14.6 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 3.3 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.3 8.6 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.3 2.2 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.3 5.9 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.3 4.1 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.3 14.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.3 5.5 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.2 5.8 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.2 7.5 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.2 7.3 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.2 11.7 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 4.6 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.2 14.0 REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH Genes involved in NCAM signaling for neurite out-growth
0.2 3.5 REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.2 9.3 REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.2 2.7 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 2.5 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 4.1 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 3.2 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 8.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 1.7 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.2 5.0 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 3.0 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.2 2.1 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 1.5 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 6.6 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 1.8 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 1.9 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 5.9 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 4.4 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 7.8 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 4.0 REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 3.5 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 1.5 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 4.7 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 7.9 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.1 0.9 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 2.7 REACTOME_KINESINS Genes involved in Kinesins
0.1 0.7 REACTOME_PLC_BETA_MEDIATED_EVENTS Genes involved in PLC beta mediated events
0.1 8.1 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 2.3 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 3.5 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 1.7 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.3 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.1 8.9 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.8 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.5 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 0.9 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.4 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.1 0.9 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.8 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.1 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 0.6 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.1 1.8 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 0.9 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.1 0.7 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 0.6 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.6 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 1.5 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 2.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 2.3 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.5 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.5 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.4 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 4.4 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.2 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.7 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.0 1.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.8 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 2.8 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 2.5 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.1 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.7 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.3 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.9 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.6 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.9 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 0.2 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines