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GSE58827: Dynamics of the Mouse Liver

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Results for Hmx2

Z-value: 0.74

Motif logo

Transcription factors associated with Hmx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000050100.7 H6 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hmx2mm10_v2_chr7_+_131548755_131548773-0.029.3e-01Click!

Activity profile of Hmx2 motif

Sorted Z-values of Hmx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_146079254 6.76 ENSMUST00000035571.8
cytochrome P450, family 3, subfamily a, polypeptide 59
chr19_-_7966000 5.60 ENSMUST00000182102.1
ENSMUST00000075619.4
solute carrier family 22, member 27
chr13_-_23914998 4.58 ENSMUST00000021769.8
ENSMUST00000110407.2
solute carrier family 17 (sodium phosphate), member 4
chr2_-_24048857 3.03 ENSMUST00000114497.1
histamine N-methyltransferase
chr19_+_12633507 3.02 ENSMUST00000119960.1
glycine-N-acyltransferase
chr19_-_8405060 2.92 ENSMUST00000064507.5
ENSMUST00000120540.1
ENSMUST00000096269.4
solute carrier family 22, member 30
chr2_-_24049389 2.92 ENSMUST00000051416.5
histamine N-methyltransferase
chr19_+_12633303 2.76 ENSMUST00000044976.5
glycine-N-acyltransferase
chr13_+_4436094 2.65 ENSMUST00000156277.1
aldo-keto reductase family 1, member C6
chr19_-_58454435 2.12 ENSMUST00000169850.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr19_-_8131982 1.97 ENSMUST00000065651.4
solute carrier family 22, member 28
chr4_-_62054112 1.93 ENSMUST00000074018.3
major urinary protein 20
chr12_+_8771317 1.75 ENSMUST00000020911.7
syndecan 1
chr5_-_146009598 1.70 ENSMUST00000138870.1
ENSMUST00000068317.6
cytochrome P450, family 3, subfamily a, polypeptide 25
chr7_+_119607014 1.51 ENSMUST00000126367.1
acyl-CoA synthetase medium-chain family member 1
chr11_-_46389509 1.49 ENSMUST00000020664.6
IL2 inducible T cell kinase
chr16_-_57167307 1.41 ENSMUST00000023432.8
nitrilase family, member 2
chr3_+_94372794 1.41 ENSMUST00000029795.3
RAR-related orphan receptor gamma
chr5_+_8660059 1.39 ENSMUST00000047753.4
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
chr17_+_46428930 1.32 ENSMUST00000024764.5
ENSMUST00000165993.1
cysteine-rich protein 3
chr3_+_19957240 1.28 ENSMUST00000108325.2
ceruloplasmin
chr11_-_46389471 1.24 ENSMUST00000109237.2
IL2 inducible T cell kinase
chr17_+_46428917 1.18 ENSMUST00000113465.3
cysteine-rich protein 3
chr4_-_96553617 1.17 ENSMUST00000030303.5
cytochrome P450, family 2, subfamily j, polypeptide 6
chr1_+_91298354 1.12 ENSMUST00000142488.1
ENSMUST00000124832.1
ENSMUST00000147523.1
selenocysteine lyase
chr9_-_15301555 1.10 ENSMUST00000034414.8
RIKEN cDNA 4931406C07 gene
chr1_-_162866502 1.09 ENSMUST00000046049.7
flavin containing monooxygenase 1
chr19_+_29945782 1.08 ENSMUST00000025724.8
interleukin 33
chr13_-_62888282 1.04 ENSMUST00000092888.4
fructose bisphosphatase 1
chr2_+_167421706 1.02 ENSMUST00000047815.6
ENSMUST00000109218.1
ENSMUST00000073873.3
solute carrier family 9 (sodium/hydrogen exchanger), member 8
chrX_+_139563316 0.99 ENSMUST00000113027.1
ring finger protein 128
chr1_+_91298334 0.95 ENSMUST00000027532.6
selenocysteine lyase
chr2_-_75938407 0.90 ENSMUST00000099996.3
tetratricopeptide repeat domain 30B
chr18_+_4993795 0.89 ENSMUST00000153016.1
supervillin
chr4_+_147492417 0.88 ENSMUST00000105721.2
predicted gene 13152
chr12_+_8973892 0.86 ENSMUST00000085745.6
ENSMUST00000111113.2
WD repeat domain 35
chr17_-_34628380 0.83 ENSMUST00000167097.2
palmitoyl-protein thioesterase 2
chr10_-_19907645 0.82 ENSMUST00000166511.1
ENSMUST00000020182.8
peroxisomal biogenesis factor 7
chr4_-_128962420 0.82 ENSMUST00000119354.1
ENSMUST00000106068.1
ENSMUST00000030581.3
arginine decarboxylase
chr14_+_48446128 0.78 ENSMUST00000124720.1
transmembrane protein 260
chr5_+_102768771 0.77 ENSMUST00000112852.1
Rho GTPase activating protein 24
chr11_-_106612928 0.75 ENSMUST00000042780.7
testis expressed gene 2
chr11_-_115037769 0.75 ENSMUST00000100239.2
predicted gene 11711
chr3_+_19957037 0.74 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
ceruloplasmin
chr1_-_172632931 0.72 ENSMUST00000027826.5
dual specificity phosphatase 23
chr11_-_99374895 0.71 ENSMUST00000006963.2
keratin 28
chr9_+_92457369 0.70 ENSMUST00000034941.7
phospholipid scramblase 4
chr2_-_127444524 0.69 ENSMUST00000028848.3
fumarylacetoacetate hydrolase domain containing 2A
chr10_-_19907545 0.67 ENSMUST00000134220.1
peroxisomal biogenesis factor 7
chr4_-_15149755 0.66 ENSMUST00000108273.1
N-terminal EF-hand calcium binding protein 1
chr14_+_48446340 0.63 ENSMUST00000111735.2
transmembrane protein 260
chr7_-_45062393 0.60 ENSMUST00000129101.1
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr3_-_116712644 0.60 ENSMUST00000029569.2
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr9_-_122310921 0.58 ENSMUST00000180685.1
predicted gene, 26797
chr11_-_99244058 0.58 ENSMUST00000103132.3
ENSMUST00000038214.6
keratin 222
chr6_-_113501818 0.58 ENSMUST00000101059.1
proline-rich transmembrane protein 3
chr11_-_100822525 0.56 ENSMUST00000107358.2
signal transducer and activator of transcription 5B
chr10_+_121365078 0.55 ENSMUST00000040344.6
glucosamine (N-acetyl)-6-sulfatase
chr16_-_44332925 0.55 ENSMUST00000136381.1
SID1 transmembrane family, member 1
chr9_-_20728219 0.53 ENSMUST00000034692.7
olfactomedin 2
chr14_-_51773578 0.53 ENSMUST00000073860.5
angiogenin, ribonuclease A family, member 4
chr9_-_50739365 0.52 ENSMUST00000117093.1
ENSMUST00000121634.1
DIX domain containing 1
chr8_+_71922810 0.52 ENSMUST00000119003.1
zinc finger protein 617
chr5_-_131308076 0.52 ENSMUST00000160609.1
Williams-Beuren syndrome chromosome region 17 homolog (human)
chr16_-_44333135 0.52 ENSMUST00000047446.6
SID1 transmembrane family, member 1
chr8_-_22694061 0.52 ENSMUST00000131767.1
inhibitor of kappaB kinase beta
chr4_+_122836236 0.51 ENSMUST00000030412.4
ENSMUST00000121870.1
ENSMUST00000097902.4
palmitoyl-protein thioesterase 1
chr8_+_25017211 0.51 ENSMUST00000033961.5
TM2 domain containing 2
chr5_+_29195983 0.51 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
ring finger protein 32
chr6_-_108185552 0.49 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
sulfatase modifying factor 1
chr18_+_62977854 0.47 ENSMUST00000150267.1
N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr1_+_164275559 0.46 ENSMUST00000027867.6
coiled-coil domain containing 181
chr14_-_18893376 0.45 ENSMUST00000151926.1
ubiquitin-conjugating enzyme E2E 2
chr2_-_26933781 0.44 ENSMUST00000154651.1
ENSMUST00000015011.3
surfeit gene 4
chr18_-_66022580 0.44 ENSMUST00000143990.1
lectin, mannose-binding, 1
chr3_+_106721672 0.43 ENSMUST00000098750.2
ENSMUST00000130105.1
ligand dependent nuclear receptor interacting factor 1
chr18_-_34579072 0.42 ENSMUST00000079287.5
NME/NM23 family member 5
chr3_-_65392546 0.42 ENSMUST00000119896.1
signal sequence receptor, gamma
chr19_-_40402267 0.42 ENSMUST00000099467.3
ENSMUST00000099466.3
ENSMUST00000165212.1
ENSMUST00000165469.1
sorbin and SH3 domain containing 1
chr15_+_102407144 0.40 ENSMUST00000169619.1
trans-acting transcription factor 1
chr17_+_35841668 0.40 ENSMUST00000174124.1
mediator of DNA damage checkpoint 1
chr19_+_58728887 0.40 ENSMUST00000048644.5
pancreatic lipase related protein 1
chr8_+_25808474 0.40 ENSMUST00000033979.4
steroidogenic acute regulatory protein
chr14_+_73237891 0.39 ENSMUST00000044405.6
lysophosphatidic acid receptor 6
chr10_+_63061582 0.39 ENSMUST00000020266.8
ENSMUST00000178684.1
phenazine biosynthesis-like protein domain containing 1
chr8_+_85432686 0.38 ENSMUST00000180883.1
RIKEN cDNA 1700051O22 Gene
chr5_-_140830430 0.37 ENSMUST00000000153.4
guanine nucleotide binding protein, alpha 12
chr12_+_84451485 0.37 ENSMUST00000137170.1
lin-52 homolog (C. elegans)
chr1_+_164115264 0.37 ENSMUST00000162746.1
selectin, platelet
chr5_-_28467093 0.37 ENSMUST00000002708.3
sonic hedgehog
chr5_+_8893677 0.35 ENSMUST00000003717.8
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr8_+_90828820 0.35 ENSMUST00000109614.2
ENSMUST00000048665.6
chromodomain helicase DNA binding protein 9
chr19_-_57197377 0.34 ENSMUST00000111546.1
actin-binding LIM protein 1
chrX_-_164027965 0.34 ENSMUST00000033739.4
carbonic anhydrase 5b, mitochondrial
chr11_+_99873389 0.34 ENSMUST00000093936.3
keratin associated protein 9-1
chr4_+_33081505 0.34 ENSMUST00000147889.1
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
chr18_+_62977826 0.33 ENSMUST00000025474.6
N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr1_-_57970104 0.33 ENSMUST00000114410.3
potassium channel tetramerisation domain containing 18
chr10_+_77613709 0.32 ENSMUST00000124024.2
SMT3 suppressor of mif two 3 homolog 3 (yeast)
chr5_+_145345254 0.32 ENSMUST00000079268.7
cytochrome P450, family 3, subfamily a, polypeptide 57
chr11_-_78080360 0.32 ENSMUST00000021183.3
Era (G-protein)-like 1 (E. coli)
chr12_-_101913116 0.32 ENSMUST00000177536.1
ENSMUST00000176728.1
ENSMUST00000021605.7
thyroid hormone receptor interactor 11
chr11_+_58171648 0.32 ENSMUST00000020820.1
mitochondrial ribosomal protein L22
chrX_-_56598069 0.32 ENSMUST00000059899.2
membrane magnesium transporter 1
chr19_-_57197435 0.31 ENSMUST00000111550.1
actin-binding LIM protein 1
chr4_-_56947411 0.31 ENSMUST00000107609.3
ENSMUST00000068792.6
transmembrane protein 245
chr2_+_30392405 0.30 ENSMUST00000113612.3
ENSMUST00000123202.1
dolichyl pyrophosphate phosphatase 1
chr18_-_63387124 0.29 ENSMUST00000047480.6
ENSMUST00000046860.5
piezo-type mechanosensitive ion channel component 2
chr9_+_86485407 0.29 ENSMUST00000034987.8
dopey family member 1
chr4_-_45532470 0.28 ENSMUST00000147448.1
src homology 2 domain-containing transforming protein B
chr12_-_40199315 0.28 ENSMUST00000095760.2
leucine-rich single-pass membrane protein 1
chr11_-_99351086 0.28 ENSMUST00000017732.2
keratin 27
chr6_-_129622685 0.28 ENSMUST00000032252.5
killer cell lectin-like receptor subfamily K, member 1
chr3_-_65392579 0.28 ENSMUST00000029414.5
signal sequence receptor, gamma
chr13_+_23684192 0.27 ENSMUST00000018246.4
histone cluster 1, H2bc
chr2_-_17460610 0.26 ENSMUST00000145492.1
nebulette
chr6_+_71282280 0.26 ENSMUST00000080949.7
lysine-rich coiled-coil 1
chr12_-_98901478 0.26 ENSMUST00000065716.6
echinoderm microtubule associated protein like 5
chr18_+_6765171 0.24 ENSMUST00000097680.5
RAB18, member RAS oncogene family
chr12_-_90969768 0.24 ENSMUST00000181184.1
RIKEN cDNA 4930544I03 gene
chr18_+_37819543 0.24 ENSMUST00000055935.5
protocadherin gamma subfamily A, 9
chr4_+_145868794 0.24 ENSMUST00000123460.1
predicted gene 13235
chr7_-_103788275 0.23 ENSMUST00000183254.1
olfactory receptor 67
chr9_-_75611308 0.23 ENSMUST00000064433.3
tropomodulin 2
chr19_-_57197496 0.22 ENSMUST00000111544.1
actin-binding LIM protein 1
chr3_-_87748619 0.22 ENSMUST00000023846.4
leucine rich repeat containing 71
chr10_+_69925800 0.21 ENSMUST00000182029.1
ankyrin 3, epithelial
chrM_+_7759 0.21 ENSMUST00000082407.1
ENSMUST00000082408.1
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr11_-_3931960 0.20 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
transcobalamin 2
chr2_-_45112890 0.20 ENSMUST00000076836.6
zinc finger E-box binding homeobox 2
chr16_+_17619503 0.20 ENSMUST00000165092.1
sphingomyelin phosphodiesterase 4
chr3_+_66985947 0.19 ENSMUST00000161726.1
ENSMUST00000160504.1
arginine/serine-rich coiled-coil 1
chr4_-_132398199 0.19 ENSMUST00000136711.1
ENSMUST00000084249.4
phosphatase and actin regulator 4
chr9_+_35423582 0.19 ENSMUST00000154652.1
cell adhesion molecule-related/down-regulated by oncogenes
chr9_-_54501496 0.19 ENSMUST00000118600.1
ENSMUST00000118163.1
Dmx-like 2
chrX_+_164373363 0.18 ENSMUST00000033751.7
c-fos induced growth factor
chr5_-_131307848 0.18 ENSMUST00000086023.5
Williams-Beuren syndrome chromosome region 17 homolog (human)
chr4_+_94739276 0.18 ENSMUST00000073939.6
ENSMUST00000102798.1
endothelial-specific receptor tyrosine kinase
chr7_-_78783026 0.17 ENSMUST00000032841.5
mitochondrial ribosomal protein L46
chr16_-_14291355 0.16 ENSMUST00000090287.3
myosin, heavy polypeptide 11, smooth muscle
chr7_-_127449109 0.16 ENSMUST00000053392.4
zinc finger protein 689
chr4_+_145670685 0.16 ENSMUST00000105738.2
predicted gene 13242
chr10_+_69925766 0.15 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
ankyrin 3, epithelial
chr3_+_107090874 0.15 ENSMUST00000060946.3
ENSMUST00000182132.1
RIKEN cDNA A930002I21 gene
chr4_+_146156824 0.15 ENSMUST00000168483.2
zinc finger protein 600
chr7_-_127448993 0.14 ENSMUST00000106299.1
zinc finger protein 689
chr5_-_28210168 0.14 ENSMUST00000117098.1
canopy 1 homolog (zebrafish)
chr4_-_147702553 0.14 ENSMUST00000117638.1
zinc finger protein 534
chr6_-_129385497 0.14 ENSMUST00000032261.6
C-type lectin domain family 12, member B
chr1_-_57970067 0.13 ENSMUST00000164963.1
potassium channel tetramerisation domain containing 18
chr5_+_114380591 0.13 ENSMUST00000074002.5
ubiquitin protein ligase E3B
chr6_+_129045893 0.13 ENSMUST00000032257.7
killer cell lectin-like receptor subfamily B member 1F
chr11_+_107479549 0.13 ENSMUST00000106750.4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr5_-_28210022 0.12 ENSMUST00000118882.1
canopy 1 homolog (zebrafish)
chrX_+_150594420 0.12 ENSMUST00000112713.2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chrX_+_38316177 0.12 ENSMUST00000016471.2
ENSMUST00000115134.1
ATPase, (Na+)/K+ transporting, beta 4 polypeptide
chr5_-_114380459 0.11 ENSMUST00000001125.5
potassium channel tetramerisation domain containing 10
chr10_+_123264076 0.11 ENSMUST00000050756.7
family with sequence similarity 19, member A2
chr5_+_15516489 0.10 ENSMUST00000178227.1
predicted gene, 21847
chr17_+_35841491 0.10 ENSMUST00000082337.6
mediator of DNA damage checkpoint 1
chr3_+_121671317 0.10 ENSMUST00000098646.3
RIKEN cDNA 4930432M17 gene
chr7_-_37772868 0.10 ENSMUST00000176205.1
zinc finger protein 536
chr5_-_26089291 0.09 ENSMUST00000094946.4
predicted gene 10471
chr4_+_145514884 0.09 ENSMUST00000105741.1
predicted gene 13225
chr5_-_26004798 0.09 ENSMUST00000168875.1
predicted gene 1979
chr5_+_100039990 0.09 ENSMUST00000169390.1
ENSMUST00000031268.6
enolase-phosphatase 1
chr11_-_67771115 0.09 ENSMUST00000051765.8
glucagon-like peptide 2 receptor
chrX_-_134111708 0.09 ENSMUST00000159259.1
ENSMUST00000113275.3
NADPH oxidase 1
chr1_+_177729814 0.08 ENSMUST00000016106.5
RIKEN cDNA 1700016C15 gene
chr18_-_65939048 0.08 ENSMUST00000025396.3
retina and anterior neural fold homeobox
chr1_+_46066738 0.08 ENSMUST00000069293.7
dynein, axonemal, heavy chain 7B
chr2_+_30982350 0.07 ENSMUST00000061544.4
ENSMUST00000138161.1
ENSMUST00000142232.1
ubiquitin specific peptidase 20
chr14_-_19823807 0.07 ENSMUST00000022341.5
RIKEN cDNA 2700060E02 gene
chr4_-_26346882 0.07 ENSMUST00000041374.7
ENSMUST00000153813.1
mannosidase, endo-alpha
chr14_+_53428708 0.07 ENSMUST00000180549.1
T cell receptor alpha variable 6-3
chr4_-_88634411 0.07 ENSMUST00000134155.1
expressed sequence C87499
chr14_-_52213379 0.07 ENSMUST00000140603.1
chromodomain helicase DNA binding protein 8
chr18_-_88894322 0.06 ENSMUST00000070116.5
ENSMUST00000125362.1
suppressor of cytokine signaling 6
chr8_-_110902442 0.06 ENSMUST00000041382.6
fucokinase
chr9_-_113708209 0.06 ENSMUST00000111861.3
ENSMUST00000035086.6
programmed cell death 6 interacting protein
chr5_-_25954344 0.05 ENSMUST00000162387.4
predicted gene, 21671
chr2_-_151432392 0.05 ENSMUST00000127020.1
predicted gene 14152
chr5_-_138272733 0.05 ENSMUST00000161665.1
ENSMUST00000100530.1
galactose-3-O-sulfotransferase 4
chr7_+_3645267 0.04 ENSMUST00000038913.9
CCR4-NOT transcription complex, subunit 3
chr14_+_52726612 0.04 ENSMUST00000184883.1
T cell receptor alpha variable 6D-3
chr1_+_109993982 0.04 ENSMUST00000027542.6
cadherin 7, type 2
chr13_-_113042243 0.04 ENSMUST00000099162.2
predicted gene 10735
chr6_-_137169678 0.04 ENSMUST00000119610.1
RAS-like, estrogen-regulated, growth-inhibitor
chr1_+_53061637 0.03 ENSMUST00000027269.5
myostatin
chr4_-_88634142 0.03 ENSMUST00000156062.1
ENSMUST00000107142.2
ENSMUST00000107143.1
ENSMUST00000053304.3
expressed sequence C87499
chr1_-_173227229 0.03 ENSMUST00000049706.5
Fc receptor, IgE, high affinity I, alpha polypeptide
chr4_+_146971976 0.03 ENSMUST00000146688.2
predicted gene 13150
chr14_-_48667508 0.03 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
orthodenticle homolog 2 (Drosophila)
chr3_+_108093109 0.03 ENSMUST00000151326.1
guanine nucleotide binding protein, alpha transducing 2
chr2_-_33087169 0.03 ENSMUST00000102810.3
GTPase activating RANGAP domain-like 3
chr19_-_57197556 0.02 ENSMUST00000099294.2
actin-binding LIM protein 1
chr4_+_99955715 0.02 ENSMUST00000102783.4
phosphoglucomutase 2
chr3_-_64719602 0.02 ENSMUST00000168072.1
vomeronasal 2, receptor 7
chr14_+_52725299 0.02 ENSMUST00000181483.1
T cell receptor alpha variable 6D-3
chr6_+_40471352 0.02 ENSMUST00000114779.2
ENSMUST00000031971.6
ENSMUST00000121360.1
ENSMUST00000117411.1
ENSMUST00000117830.1
single-stranded DNA binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Hmx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.9 GO:0001692 histamine metabolic process(GO:0001692)
0.9 2.7 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.7 10.5 GO:0015747 urate transport(GO:0015747)
0.6 1.8 GO:0048627 myoblast development(GO:0048627)
0.5 2.1 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.3 1.4 GO:0046618 drug export(GO:0046618)
0.3 1.9 GO:0008355 olfactory learning(GO:0008355)
0.3 1.0 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.2 1.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 1.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.2 1.4 GO:0006528 asparagine metabolic process(GO:0006528)
0.2 1.5 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.2 2.7 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.4 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 1.4 GO:0072615 interleukin-17 secretion(GO:0072615)
0.1 0.4 GO:1904339 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) kidney smooth muscle tissue development(GO:0072194) negative regulation of dopaminergic neuron differentiation(GO:1904339) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.6 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 1.1 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.5 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.3 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.1 0.6 GO:0070672 response to interleukin-15(GO:0070672)
0.1 1.1 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.8 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.5 GO:0098734 protein depalmitoylation(GO:0002084) positive regulation of pinocytosis(GO:0048549) macromolecule depalmitoylation(GO:0098734)
0.1 0.4 GO:1904253 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 2.0 GO:0046688 response to copper ion(GO:0046688)
0.1 0.4 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.1 0.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.9 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.2 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.4 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.5 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.5 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 4.5 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 6.0 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.2 GO:0097324 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.4 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.3 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 1.0 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.3 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.9 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 1.5 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.1 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.0 0.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.0 0.4 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.4 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.9 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.3 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 1.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.5 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 2.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.4 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 1.3 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 2.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.8 GO:0031201 SNARE complex(GO:0031201)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 8.8 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
1.4 5.8 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.9 2.7 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.7 10.5 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.6 1.9 GO:0005186 pheromone activity(GO:0005186)
0.5 2.1 GO:0070279 vitamin B6 binding(GO:0070279)
0.4 4.6 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.3 1.7 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.3 1.2 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.3 1.4 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.5 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.2 2.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 0.8 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 1.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 1.5 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 1.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.4 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.5 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.3 GO:0047874 dolichyldiphosphatase activity(GO:0047874)
0.1 1.0 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.4 GO:0042806 fucose binding(GO:0042806)
0.1 1.2 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 0.5 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 5.5 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.4 GO:0005113 patched binding(GO:0005113)
0.0 2.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.6 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.4 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 1.4 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 2.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 2.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.5 PID ATM PATHWAY ATM pathway
0.0 0.4 PID INSULIN PATHWAY Insulin Pathway
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 7.3 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 1.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 0.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 2.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.9 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.1 REACTOME BIOLOGICAL OXIDATIONS Genes involved in Biological oxidations
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription