Motif ID: Hoxa2

Z-value: 1.698


Transcription factors associated with Hoxa2:

Gene SymbolEntrez IDGene Name
Hoxa2 ENSMUSG00000014704.8 Hoxa2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hoxa2mm10_v2_chr6_-_52165413_52165413-0.473.7e-03Click!


Activity profile for motif Hoxa2.

activity profile for motif Hoxa2


Sorted Z-values histogram for motif Hoxa2

Sorted Z-values for motif Hoxa2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_63344548 29.766 ENSMUST00000030044.2
Orm1
orosomucoid 1
chr4_-_62054112 25.436 ENSMUST00000074018.3
Mup20
major urinary protein 20
chr4_-_62150810 15.940 ENSMUST00000077719.3
Mup21
major urinary protein 21
chr19_-_8131982 14.923 ENSMUST00000065651.4
Slc22a28
solute carrier family 22, member 28
chr19_-_39463067 12.065 ENSMUST00000035488.2
Cyp2c38
cytochrome P450, family 2, subfamily c, polypeptide 38
chr7_-_46742979 11.986 ENSMUST00000128088.1
Saa1
serum amyloid A 1
chr7_+_27119909 11.234 ENSMUST00000003100.8
Cyp2f2
cytochrome P450, family 2, subfamily f, polypeptide 2
chr2_+_102706356 10.688 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr7_+_44207307 10.002 ENSMUST00000077354.4
Klk1b4
kallikrein 1-related pepidase b4
chr5_-_87254804 9.925 ENSMUST00000075858.3
Ugt2b37
UDP glucuronosyltransferase 2 family, polypeptide B37
chr12_-_103457195 9.863 ENSMUST00000044687.6
Ifi27l2b
interferon, alpha-inducible protein 27 like 2B
chr9_-_48605147 9.785 ENSMUST00000034808.5
ENSMUST00000119426.1
Nnmt

nicotinamide N-methyltransferase

chr7_+_46751832 9.744 ENSMUST00000075982.2
Saa2
serum amyloid A 2
chr2_+_25700039 9.649 ENSMUST00000077667.3
Obp2a
odorant binding protein 2A
chr5_-_146009598 9.608 ENSMUST00000138870.1
ENSMUST00000068317.6
Cyp3a25

cytochrome P450, family 3, subfamily a, polypeptide 25

chr4_-_108118504 9.007 ENSMUST00000149106.1
Scp2
sterol carrier protein 2, liver
chr19_+_4711153 8.502 ENSMUST00000008991.6
Sptbn2
spectrin beta, non-erythrocytic 2
chr12_-_104013640 8.097 ENSMUST00000058464.4
Serpina9
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
chr19_+_12633507 7.906 ENSMUST00000119960.1
Glyat
glycine-N-acyltransferase
chr8_-_5105232 7.831 ENSMUST00000023835.1
Slc10a2
solute carrier family 10, member 2
chr4_+_63356152 7.798 ENSMUST00000006687.4
Orm3
orosomucoid 3
chr19_-_4042165 7.032 ENSMUST00000042700.9
Gstp2
glutathione S-transferase, pi 2
chr11_-_58613481 6.858 ENSMUST00000048801.7
2210407C18Rik
RIKEN cDNA 2210407C18 gene
chr3_+_130617645 6.858 ENSMUST00000163620.1
Etnppl
ethanolamine phosphate phospholyase
chr3_+_130617448 6.716 ENSMUST00000166187.1
ENSMUST00000072271.6
Etnppl

ethanolamine phosphate phospholyase

chr1_-_121327734 6.112 ENSMUST00000160968.1
ENSMUST00000162582.1
Insig2

insulin induced gene 2

chr18_-_61911783 5.929 ENSMUST00000049378.8
ENSMUST00000166783.1
Ablim3

actin binding LIM protein family, member 3

chr19_+_12633303 5.837 ENSMUST00000044976.5
Glyat
glycine-N-acyltransferase
chr5_-_87424201 5.825 ENSMUST00000072818.5
Ugt2b38
UDP glucuronosyltransferase 2 family, polypeptide B38
chr14_+_65971049 5.808 ENSMUST00000128539.1
Clu
clusterin
chr15_+_82555087 5.635 ENSMUST00000068861.6
Cyp2d12
cytochrome P450, family 2, subfamily d, polypeptide 12
chr12_+_108334341 5.544 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr5_-_66173051 5.398 ENSMUST00000113726.1
Rbm47
RNA binding motif protein 47
chr5_-_87140318 5.383 ENSMUST00000067790.6
ENSMUST00000113327.1
Ugt2b5

UDP glucuronosyltransferase 2 family, polypeptide B5

chr3_-_107943362 5.349 ENSMUST00000106683.1
Gstm6
glutathione S-transferase, mu 6
chr4_-_108118528 5.323 ENSMUST00000030340.8
Scp2
sterol carrier protein 2, liver
chrX_-_143933089 5.322 ENSMUST00000087313.3
Dcx
doublecortin
chr15_+_82452372 5.248 ENSMUST00000089129.5
Cyp2d9
cytochrome P450, family 2, subfamily d, polypeptide 9
chr8_-_110039330 5.241 ENSMUST00000109222.2
Chst4
carbohydrate (chondroitin 6/keratan) sulfotransferase 4
chr1_+_88134786 5.185 ENSMUST00000113134.1
ENSMUST00000140092.1
Ugt1a6a

UDP glucuronosyltransferase 1 family, polypeptide A6A

chr1_-_139858684 5.167 ENSMUST00000094489.3
Cfhr2
complement factor H-related 2
chr6_-_83677807 5.124 ENSMUST00000037882.6
Cd207
CD207 antigen
chr17_+_3397189 5.100 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr2_-_84775420 5.035 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr3_-_107943705 4.969 ENSMUST00000106680.1
ENSMUST00000106684.1
ENSMUST00000106685.2
Gstm6


glutathione S-transferase, mu 6


chr16_+_96361654 4.915 ENSMUST00000113794.1
Igsf5
immunoglobulin superfamily, member 5
chr8_-_94696223 4.789 ENSMUST00000034227.4
Pllp
plasma membrane proteolipid
chr14_+_30886521 4.730 ENSMUST00000168782.1
Itih4
inter alpha-trypsin inhibitor, heavy chain 4
chr14_+_30886476 4.686 ENSMUST00000006703.6
ENSMUST00000078490.5
ENSMUST00000120269.2
Itih4


inter alpha-trypsin inhibitor, heavy chain 4


chr2_-_84775388 4.674 ENSMUST00000023994.3
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr1_-_121327672 4.640 ENSMUST00000159085.1
ENSMUST00000159125.1
ENSMUST00000161818.1
Insig2


insulin induced gene 2


chr17_-_34804546 4.598 ENSMUST00000025223.8
Cyp21a1
cytochrome P450, family 21, subfamily a, polypeptide 1
chr1_+_88103229 4.556 ENSMUST00000113135.3
ENSMUST00000113138.1
Ugt1a6a
Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6A
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr11_+_83703991 4.504 ENSMUST00000092836.5
Wfdc17
WAP four-disulfide core domain 17
chr1_-_139560158 4.437 ENSMUST00000160423.1
ENSMUST00000023965.5
Cfhr1

complement factor H-related 1

chr13_+_4059565 4.425 ENSMUST00000041768.6
Akr1c14
aldo-keto reductase family 1, member C14
chr9_+_22225702 4.385 ENSMUST00000072465.7
Zfp809
zinc finger protein 809
chr10_-_41611319 4.341 ENSMUST00000179614.1
Ccdc162
coiled-coil domain containing 162
chr6_-_89216237 4.306 ENSMUST00000079186.2
Gm839
predicted gene 839
chr19_+_37685581 4.279 ENSMUST00000073391.4
Cyp26c1
cytochrome P450, family 26, subfamily c, polypeptide 1
chr1_-_121327776 4.258 ENSMUST00000160688.1
Insig2
insulin induced gene 2
chr6_+_124304646 4.200 ENSMUST00000112541.2
ENSMUST00000032234.2
Cd163

CD163 antigen

chr15_-_82620907 4.173 ENSMUST00000109515.1
Cyp2d34
cytochrome P450, family 2, subfamily d, polypeptide 34
chr13_+_23807027 4.168 ENSMUST00000006786.4
ENSMUST00000099697.2
Slc17a2

solute carrier family 17 (sodium phosphate), member 2

chr11_+_102041509 4.126 ENSMUST00000123895.1
ENSMUST00000017453.5
ENSMUST00000107163.2
ENSMUST00000107164.2
Cd300lg



CD300 antigen like family member G



chr9_-_70141484 4.125 ENSMUST00000034749.8
Fam81a
family with sequence similarity 81, member A
chr11_-_106580594 4.118 ENSMUST00000153870.1
Tex2
testis expressed gene 2
chr3_-_107943390 4.103 ENSMUST00000106681.1
Gstm6
glutathione S-transferase, mu 6
chr3_+_62419668 4.047 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr14_+_51091077 4.044 ENSMUST00000022428.5
ENSMUST00000171688.1
Rnase4
Ang
ribonuclease, RNase A family 4
angiogenin, ribonuclease, RNase A family, 5
chr7_+_24587543 3.892 ENSMUST00000077191.6
Ethe1
ethylmalonic encephalopathy 1
chr1_-_153900198 3.824 ENSMUST00000123490.1
5830403L16Rik
RIKEN cDNA 5830403L16 gene
chr16_+_43247278 3.818 ENSMUST00000114691.1
ENSMUST00000079441.6
Zbtb20

zinc finger and BTB domain containing 20

chr14_+_65971164 3.808 ENSMUST00000144619.1
Clu
clusterin
chr3_+_81996922 3.754 ENSMUST00000029641.3
Asic5
acid-sensing (proton-gated) ion channel family member 5
chr7_-_100658364 3.716 ENSMUST00000107043.1
Plekhb1
pleckstrin homology domain containing, family B (evectins) member 1
chr6_-_28126125 3.689 ENSMUST00000115324.2
ENSMUST00000090512.3
Grm8

glutamate receptor, metabotropic 8

chr15_+_31224371 3.688 ENSMUST00000044524.9
Dap
death-associated protein
chr6_+_121346618 3.656 ENSMUST00000032200.9
Slc6a12
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
chr13_-_4279420 3.609 ENSMUST00000021632.3
Akr1c12
aldo-keto reductase family 1, member C12
chr1_+_153899937 3.596 ENSMUST00000086199.5
Glul
glutamate-ammonia ligase (glutamine synthetase)
chr1_+_191978247 3.583 ENSMUST00000175680.1
Rd3
retinal degeneration 3
chr18_-_56562261 3.558 ENSMUST00000066208.6
ENSMUST00000172734.1
Aldh7a1

aldehyde dehydrogenase family 7, member A1

chr7_-_71351485 3.517 ENSMUST00000094315.2
Gm10295
predicted gene 10295
chr6_-_21851914 3.469 ENSMUST00000134635.1
ENSMUST00000123116.1
ENSMUST00000120965.1
Tspan12


tetraspanin 12


chr4_-_109202217 3.382 ENSMUST00000160774.1
ENSMUST00000030288.7
ENSMUST00000162787.2
Osbpl9


oxysterol binding protein-like 9


chr18_-_56562187 3.378 ENSMUST00000171844.2
Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr5_-_130024280 3.339 ENSMUST00000161640.1
ENSMUST00000161884.1
ENSMUST00000161094.1
Asl


argininosuccinate lyase


chr2_-_91195035 3.270 ENSMUST00000111356.1
Nr1h3
nuclear receptor subfamily 1, group H, member 3
chr7_-_98562982 3.243 ENSMUST00000069035.4
A630091E08Rik
RIKEN cDNA A630091E08 gene
chr3_-_107931817 3.191 ENSMUST00000004137.4
Gstm7
glutathione S-transferase, mu 7
chr4_-_96507386 3.179 ENSMUST00000124729.3
Cyp2j8
cytochrome P450, family 2, subfamily j, polypeptide 8
chr13_+_4233730 3.177 ENSMUST00000081326.6
Akr1c19
aldo-keto reductase family 1, member C19
chr18_-_56562215 3.147 ENSMUST00000170309.1
Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr13_-_41847626 3.001 ENSMUST00000121404.1
Adtrp
androgen dependent TFPI regulating protein
chr3_-_113574758 2.975 ENSMUST00000106540.1
Amy1
amylase 1, salivary
chr13_+_4049001 2.970 ENSMUST00000118717.2
Akr1c14
aldo-keto reductase family 1, member C14
chr3_-_157925056 2.963 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr10_-_18227473 2.943 ENSMUST00000174592.1
Ccdc28a
coiled-coil domain containing 28A
chr13_-_41847599 2.931 ENSMUST00000179758.1
Adtrp
androgen dependent TFPI regulating protein
chr15_+_99717515 2.879 ENSMUST00000023760.6
ENSMUST00000162194.1
Gpd1

glycerol-3-phosphate dehydrogenase 1 (soluble)

chr15_+_31568791 2.870 ENSMUST00000162532.1
Cmbl
carboxymethylenebutenolidase-like (Pseudomonas)
chr7_-_24587612 2.852 ENSMUST00000094705.2
Zfp575
zinc finger protein 575
chr4_-_115496129 2.805 ENSMUST00000030487.2
Cyp4a14
cytochrome P450, family 4, subfamily a, polypeptide 14
chr11_+_104231390 2.797 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chr3_-_39359128 2.726 ENSMUST00000056409.2
Gm9845
predicted pseudogene 9845
chr18_-_3299537 2.703 ENSMUST00000129435.1
ENSMUST00000122958.1
Crem

cAMP responsive element modulator

chr7_+_143823135 2.673 ENSMUST00000128454.1
ENSMUST00000073878.5
Dhcr7

7-dehydrocholesterol reductase

chr10_-_75797528 2.634 ENSMUST00000120177.1
Gstt1
glutathione S-transferase, theta 1
chrX_-_19237841 2.608 ENSMUST00000180592.1
Gm26652
predicted gene, 26652
chr3_-_98588807 2.587 ENSMUST00000178221.1
Gm10681
predicted gene 10681
chr1_-_90967667 2.583 ENSMUST00000131428.1
Rab17
RAB17, member RAS oncogene family
chrX_+_7722267 2.573 ENSMUST00000125991.1
ENSMUST00000148624.1
Wdr45

WD repeat domain 45

chr10_+_81575257 2.566 ENSMUST00000135211.1
Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr4_+_95557494 2.565 ENSMUST00000079223.4
ENSMUST00000177394.1
Fggy

FGGY carbohydrate kinase domain containing

chr6_+_48554776 2.558 ENSMUST00000114545.1
ENSMUST00000153222.1
ENSMUST00000101436.2
Lrrc61


leucine rich repeat containing 61


chrX_+_7722214 2.557 ENSMUST00000043045.2
ENSMUST00000116634.1
ENSMUST00000115689.3
ENSMUST00000131077.1
ENSMUST00000115688.1
ENSMUST00000116633.1
Wdr45





WD repeat domain 45





chr6_+_108828633 2.526 ENSMUST00000089162.3
Edem1
ER degradation enhancer, mannosidase alpha-like 1
chr10_+_81575306 2.510 ENSMUST00000146916.1
Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr10_-_109009055 2.508 ENSMUST00000156979.1
Syt1
synaptotagmin I
chrX_-_143933204 2.493 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr4_-_83285141 2.483 ENSMUST00000150522.1
Ttc39b
tetratricopeptide repeat domain 39B
chr12_+_9029982 2.454 ENSMUST00000085741.1
Ttc32
tetratricopeptide repeat domain 32
chr17_-_31165045 2.454 ENSMUST00000024831.6
Tff1
trefoil factor 1
chr18_+_9707639 2.452 ENSMUST00000040069.8
Colec12
collectin sub-family member 12
chr7_+_43995833 2.440 ENSMUST00000007156.4
Klk1b11
kallikrein 1-related peptidase b11
chr9_+_75037614 2.429 ENSMUST00000168166.1
ENSMUST00000169492.1
ENSMUST00000170308.1
Arpp19


cAMP-regulated phosphoprotein 19


chr2_-_134554348 2.386 ENSMUST00000028704.2
Hao1
hydroxyacid oxidase 1, liver
chr15_+_59648350 2.382 ENSMUST00000067543.6
Trib1
tribbles homolog 1 (Drosophila)
chr1_+_88055377 2.360 ENSMUST00000138182.1
ENSMUST00000113142.3
Ugt1a10

UDP glycosyltransferase 1 family, polypeptide A10

chr7_+_140125651 2.349 ENSMUST00000026537.5
ENSMUST00000097967.3
Paox

polyamine oxidase (exo-N4-amino)

chr7_+_113207465 2.327 ENSMUST00000047321.7
Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr9_+_123021315 2.286 ENSMUST00000084733.5
Tmem42
transmembrane protein 42
chr19_+_24875679 2.262 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr17_+_37193889 2.258 ENSMUST00000038844.6
Ubd
ubiquitin D
chr9_+_75037744 2.254 ENSMUST00000168301.1
Arpp19
cAMP-regulated phosphoprotein 19
chr7_-_46715676 2.247 ENSMUST00000006956.7
Saa3
serum amyloid A 3
chr12_+_57564111 2.235 ENSMUST00000101398.3
Ttc6
tetratricopeptide repeat domain 6
chr2_+_116900152 2.209 ENSMUST00000126467.1
ENSMUST00000128305.1
ENSMUST00000155323.1
D330050G23Rik


RIKEN cDNA D330050G23 gene


chr7_-_108930151 2.198 ENSMUST00000055745.3
Nlrp10
NLR family, pyrin domain containing 10
chr2_-_91195097 2.187 ENSMUST00000002177.2
ENSMUST00000111354.1
Nr1h3

nuclear receptor subfamily 1, group H, member 3

chr13_-_23934156 2.175 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chr17_-_32424139 2.172 ENSMUST00000114455.1
Pglyrp2
peptidoglycan recognition protein 2
chr19_-_44029201 2.166 ENSMUST00000026211.8
Cyp2c44
cytochrome P450, family 2, subfamily c, polypeptide 44
chr10_+_57784914 2.164 ENSMUST00000165013.1
Fabp7
fatty acid binding protein 7, brain
chr13_-_24937585 2.156 ENSMUST00000037615.6
Aldh5a1
aldhehyde dehydrogenase family 5, subfamily A1
chr1_+_88055467 2.154 ENSMUST00000173325.1
Ugt1a10
UDP glycosyltransferase 1 family, polypeptide A10
chr10_+_29143996 2.151 ENSMUST00000092629.2
Soga3
SOGA family member 3
chr16_+_90220742 2.139 ENSMUST00000023707.9
Sod1
superoxide dismutase 1, soluble
chr16_-_75766758 2.132 ENSMUST00000114244.1
ENSMUST00000046283.8
Hspa13

heat shock protein 70 family, member 13

chr5_+_139543889 2.107 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr5_+_125475814 2.102 ENSMUST00000031445.3
Aacs
acetoacetyl-CoA synthetase
chr7_+_29238434 2.096 ENSMUST00000108237.1
Yif1b
Yip1 interacting factor homolog B (S. cerevisiae)
chr3_-_88762244 2.089 ENSMUST00000183267.1
Syt11
synaptotagmin XI
chr9_+_121710389 2.069 ENSMUST00000035113.9
Deb1
differentially expressed in B16F10 1
chr18_-_12819842 2.067 ENSMUST00000119043.1
Osbpl1a
oxysterol binding protein-like 1A
chr17_+_30485511 2.062 ENSMUST00000064223.1
Gm9874
predicted gene 9874
chr4_-_35157404 2.058 ENSMUST00000102975.3
Mob3b
MOB kinase activator 3B
chr16_-_36990449 2.026 ENSMUST00000075869.6
Fbxo40
F-box protein 40
chr9_+_75037809 2.004 ENSMUST00000167885.1
Arpp19
cAMP-regulated phosphoprotein 19
chr11_-_86671169 2.003 ENSMUST00000143991.1
Vmp1
vacuole membrane protein 1
chr12_+_4769375 2.002 ENSMUST00000178879.1
Pfn4
profilin family, member 4
chr4_+_116596672 1.984 ENSMUST00000051869.7
Ccdc17
coiled-coil domain containing 17
chrX_+_100428906 1.984 ENSMUST00000060241.2
Otud6a
OTU domain containing 6A
chr9_+_75037712 1.980 ENSMUST00000007800.7
Arpp19
cAMP-regulated phosphoprotein 19
chr8_+_47824459 1.965 ENSMUST00000038693.6
Cldn22
claudin 22
chr5_+_3596066 1.958 ENSMUST00000006061.6
ENSMUST00000121291.1
ENSMUST00000142516.1
Pex1


peroxisomal biogenesis factor 1


chr2_-_177925604 1.921 ENSMUST00000108934.2
ENSMUST00000081529.4
C330013J21Rik

RIKEN cDNA C330013J21 gene

chr11_-_40755201 1.916 ENSMUST00000020576.7
Ccng1
cyclin G1
chr6_-_142278836 1.915 ENSMUST00000111825.3
Slco1a5
solute carrier organic anion transporter family, member 1a5
chr18_-_35498856 1.905 ENSMUST00000025215.8
Sil1
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr4_+_102589687 1.904 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr7_+_130936172 1.900 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr2_+_96318014 1.895 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr14_+_51007911 1.878 ENSMUST00000022424.6
Rnase10
ribonuclease, RNase A family, 10 (non-active)
chr15_+_59315030 1.852 ENSMUST00000022977.7
Sqle
squalene epoxidase
chr8_+_21938352 1.843 ENSMUST00000076786.2
Defb35
defensin beta 35
chr10_+_81575499 1.841 ENSMUST00000143285.1
ENSMUST00000146358.1
Tle2

transducin-like enhancer of split 2, homolog of Drosophila E(spl)

chr10_+_57784859 1.835 ENSMUST00000020024.5
Fabp7
fatty acid binding protein 7, brain
chr4_-_147936713 1.835 ENSMUST00000105712.1
ENSMUST00000019199.7
Plod1

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

chrX_+_142226765 1.822 ENSMUST00000112916.2
Nxt2
nuclear transport factor 2-like export factor 2
chr9_+_123806468 1.796 ENSMUST00000049810.7
Cxcr6
chemokine (C-X-C motif) receptor 6
chr19_-_8218832 1.774 ENSMUST00000113298.2
Slc22a29
solute carrier family 22. member 29
chr9_+_75037838 1.765 ENSMUST00000169188.1
Arpp19
cAMP-regulated phosphoprotein 19
chr18_-_3299452 1.728 ENSMUST00000126578.1
Crem
cAMP responsive element modulator
chr11_+_94327984 1.727 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr1_+_107422681 1.723 ENSMUST00000112710.1
ENSMUST00000086690.4
Serpinb7

serine (or cysteine) peptidase inhibitor, clade B, member 7

chr6_-_114969986 1.723 ENSMUST00000139640.1
Vgll4
vestigial like 4 (Drosophila)
chrX_-_134161928 1.720 ENSMUST00000033611.4
Xkrx
X Kell blood group precursor related X linked
chr3_-_65392579 1.714 ENSMUST00000029414.5
Ssr3
signal sequence receptor, gamma
chr1_-_155527083 1.707 ENSMUST00000097531.2
Gm5532
predicted gene 5532
chrX_-_36874111 1.693 ENSMUST00000047486.5
C330007P06Rik
RIKEN cDNA C330007P06 gene
chr13_-_4609122 1.675 ENSMUST00000110691.3
ENSMUST00000091848.5
Akr1e1

aldo-keto reductase family 1, member E1

chr6_-_24527546 1.672 ENSMUST00000118558.1
Ndufa5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr14_-_56159579 1.667 ENSMUST00000015578.4
Gzmg
granzyme G
chr18_-_6136057 1.650 ENSMUST00000182559.1
Arhgap12
Rho GTPase activating protein 12
chr11_+_104231573 1.640 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
Mapt


microtubule-associated protein tau


chr15_+_102977032 1.632 ENSMUST00000001706.6
Hoxc9
homeobox C9
chr17_+_24426676 1.628 ENSMUST00000024946.5
Eci1
enoyl-Coenzyme A delta isomerase 1
chr2_-_60284292 1.626 ENSMUST00000028356.8
ENSMUST00000074606.4
Cd302

CD302 antigen


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 25.4 GO:0008355 olfactory learning(GO:0008355)
3.6 14.3 GO:1901373 lipid hydroperoxide transport(GO:1901373)
3.5 13.9 GO:0042196 chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
3.2 9.7 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.8 5.5 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
1.7 5.2 GO:0042339 keratan sulfate metabolic process(GO:0042339)
1.6 9.6 GO:1905894 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) response to tunicamycin(GO:1904576) cellular response to tunicamycin(GO:1904577) regulation of cellular response to thapsigargin(GO:1905891) negative regulation of cellular response to thapsigargin(GO:1905892) regulation of cellular response to tunicamycin(GO:1905894) negative regulation of cellular response to tunicamycin(GO:1905895)
1.5 10.7 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.5 4.4 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
1.4 6.9 GO:0019676 ammonia assimilation cycle(GO:0019676)
1.3 6.7 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
1.2 67.4 GO:0006953 acute-phase response(GO:0006953)
1.2 16.7 GO:0015747 urate transport(GO:0015747)
1.2 14.3 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
1.1 2.2 GO:0032824 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
1.1 4.3 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
1.0 4.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
1.0 3.0 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343)
1.0 2.9 GO:0006127 glycerophosphate shuttle(GO:0006127) glycerol-3-phosphate catabolic process(GO:0046168)
0.9 3.7 GO:0009992 cellular water homeostasis(GO:0009992)
0.9 2.7 GO:0016132 brassinosteroid metabolic process(GO:0016131) brassinosteroid biosynthetic process(GO:0016132)
0.9 15.0 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.9 1.7 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.8 2.5 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.8 7.3 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.8 2.4 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.8 3.9 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.7 2.1 GO:1990927 clathrin-coated pit assembly(GO:1905224) calcium ion regulated lysosome exocytosis(GO:1990927)
0.7 2.0 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.6 1.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.6 4.8 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.6 2.4 GO:0009441 glycolate metabolic process(GO:0009441)
0.6 4.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.5 5.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.5 3.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.5 1.6 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.5 1.5 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.5 2.5 GO:2000562 regulation of natural killer cell degranulation(GO:0043321) negative regulation of interferon-gamma secretion(GO:1902714) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.5 2.3 GO:0008295 spermidine biosynthetic process(GO:0008295) putrescine biosynthetic process(GO:0009446)
0.5 1.9 GO:1902093 positive regulation of flagellated sperm motility(GO:1902093)
0.5 2.3 GO:0090403 oxidative stress-induced premature senescence(GO:0090403) positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.5 1.8 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.5 1.8 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.4 14.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.4 7.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.4 1.7 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.4 2.2 GO:0006538 glutamate catabolic process(GO:0006538)
0.4 0.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.4 1.3 GO:0002591 positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591) peptide antigen transport(GO:0046968)
0.4 15.1 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.4 5.0 GO:0042448 progesterone metabolic process(GO:0042448)
0.4 1.2 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.4 5.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.4 1.2 GO:0051030 snRNA transport(GO:0051030)
0.4 1.1 GO:0016598 protein arginylation(GO:0016598)
0.4 2.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.4 2.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.3 5.1 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.3 1.0 GO:0038129 ERBB3 signaling pathway(GO:0038129) regulation of protein localization to endoplasmic reticulum(GO:1905550) positive regulation of protein localization to endoplasmic reticulum(GO:1905552)
0.3 1.3 GO:0002188 translation reinitiation(GO:0002188)
0.3 0.3 GO:0070347 brown fat cell proliferation(GO:0070342) regulation of brown fat cell proliferation(GO:0070347)
0.3 10.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.3 1.6 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.3 10.0 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.3 8.5 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.3 0.9 GO:0070625 zymogen granule exocytosis(GO:0070625)
0.3 1.2 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.3 9.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.3 1.1 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.3 0.8 GO:1900114 positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.3 1.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.3 3.7 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.3 4.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.3 1.0 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.2 1.5 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 1.5 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.2 2.5 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.2 2.2 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.2 0.9 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.2 2.5 GO:0005513 detection of calcium ion(GO:0005513)
0.2 0.9 GO:0021564 vagus nerve development(GO:0021564)
0.2 1.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 2.0 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 4.0 GO:0060134 prepulse inhibition(GO:0060134)
0.2 1.9 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.2 2.5 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.2 0.6 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.2 2.0 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.2 1.6 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.2 0.8 GO:0060468 prevention of polyspermy(GO:0060468)
0.2 0.8 GO:0061734 parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization(GO:0061734)
0.2 4.0 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 0.5 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 1.2 GO:0015862 uridine transport(GO:0015862)
0.2 1.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.2 0.9 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.2 1.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.2 1.0 GO:1902603 carnitine transmembrane transport(GO:1902603)
0.2 1.0 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 2.6 GO:0019321 pentose metabolic process(GO:0019321)
0.2 0.5 GO:0090081 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.2 0.5 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.2 0.5 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.2 0.5 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.2 0.7 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.2 1.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.2 2.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 2.3 GO:0070842 aggresome assembly(GO:0070842)
0.2 1.7 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.2 2.8 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.2 0.5 GO:0002017 regulation of blood volume by renal aldosterone(GO:0002017)
0.2 1.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 1.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.2 1.2 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.3 GO:0006013 mannose metabolic process(GO:0006013)
0.1 1.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.6 GO:2000864 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721) estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864)
0.1 0.4 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.1 2.1 GO:0030497 fatty acid elongation(GO:0030497)
0.1 0.5 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 1.2 GO:0061042 vascular wound healing(GO:0061042)
0.1 0.6 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.1 0.4 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.8 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.1 0.5 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.1 0.8 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.6 GO:2001025 positive regulation of response to drug(GO:2001025)
0.1 0.9 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 1.0 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442)
0.1 2.1 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 3.6 GO:0010842 retina layer formation(GO:0010842)
0.1 0.4 GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.1 0.5 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.1 0.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.7 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 0.8 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.4 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.1 0.6 GO:0060459 left lung development(GO:0060459) left lung morphogenesis(GO:0060460)
0.1 1.1 GO:0051255 spindle midzone assembly(GO:0051255)
0.1 0.5 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.6 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 3.6 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.1 1.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 3.9 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.1 1.0 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.9 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.1 0.3 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 6.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 1.0 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 3.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.0 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.7 GO:2000303 regulation of ceramide biosynthetic process(GO:2000303)
0.1 1.1 GO:0000076 DNA replication checkpoint(GO:0000076)
0.1 1.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 2.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.6 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.1 1.4 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.1 0.6 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.1 0.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 2.5 GO:0046677 response to antibiotic(GO:0046677)
0.1 0.6 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.2 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 1.0 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.1 0.5 GO:0097475 motor neuron migration(GO:0097475)
0.1 1.2 GO:0034063 stress granule assembly(GO:0034063)
0.1 1.6 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.8 GO:0060539 diaphragm development(GO:0060539)
0.1 0.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 1.6 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 0.7 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.1 0.2 GO:0061518 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518)
0.1 0.9 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.8 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.2 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.1 2.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 1.9 GO:0019835 cytolysis(GO:0019835)
0.1 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network formation(GO:0071787)
0.0 0.4 GO:0051694 neuron-neuron synaptic transmission(GO:0007270) pointed-end actin filament capping(GO:0051694)
0.0 0.7 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.6 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.5 GO:2000484 positive regulation of interleukin-8 secretion(GO:2000484)
0.0 0.9 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.2 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.6 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 2.0 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 4.8 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.2 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 1.9 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 10.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.8 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 2.1 GO:0007584 response to nutrient(GO:0007584)
0.0 0.8 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 2.4 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.7 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 2.2 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.2 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 4.6 GO:0009636 response to toxic substance(GO:0009636)
0.0 4.6 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.5 GO:0036065 fucosylation(GO:0036065)
0.0 0.6 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.9 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 1.6 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.4 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 1.6 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.0 GO:0030433 ubiquitin-dependent ERAD pathway(GO:0030433)
0.0 1.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.3 GO:0031424 keratinization(GO:0031424)
0.0 0.3 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.3 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.0 0.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.3 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 1.0 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 2.3 GO:0007601 visual perception(GO:0007601)
0.0 0.9 GO:0051972 regulation of telomerase activity(GO:0051972)
0.0 0.8 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.5 GO:0048713 regulation of oligodendrocyte differentiation(GO:0048713)
0.0 1.1 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.0 1.6 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 1.0 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.3 GO:0007568 aging(GO:0007568)
0.0 4.0 GO:0032259 methylation(GO:0032259)
0.0 0.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.3 GO:0050777 negative regulation of immune response(GO:0050777)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
1.9 15.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
1.3 4.0 GO:0032311 angiogenin-PRI complex(GO:0032311)
1.3 16.9 GO:0097418 neurofibrillary tangle(GO:0097418)
1.2 8.5 GO:0008091 spectrin(GO:0008091)
1.0 12.7 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.8 24.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.6 2.9 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 1.7 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.3 5.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.3 10.7 GO:0030673 axolemma(GO:0030673)
0.3 1.1 GO:1902636 kinociliary basal body(GO:1902636)
0.3 0.8 GO:0060473 cortical granule(GO:0060473)
0.3 3.3 GO:0070852 cell body fiber(GO:0070852)
0.3 1.0 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 4.6 GO:0031045 dense core granule(GO:0031045)
0.2 0.7 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 1.4 GO:0000938 GARP complex(GO:0000938)
0.2 2.0 GO:0030478 actin cap(GO:0030478)
0.2 1.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 0.8 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.2 1.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 0.8 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.2 1.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 0.5 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.2 4.8 GO:0043218 compact myelin(GO:0043218)
0.2 2.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 2.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 1.3 GO:0042825 TAP complex(GO:0042825)
0.2 1.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.2 0.9 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 21.3 GO:0072562 blood microparticle(GO:0072562)
0.1 2.5 GO:0033391 chromatoid body(GO:0033391)
0.1 1.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.5 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 2.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 4.8 GO:0030134 COPII-coated ER to Golgi transport vesicle(GO:0030134)
0.1 0.9 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.9 GO:0005787 signal peptidase complex(GO:0005787)
0.1 1.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.6 GO:0044308 axonal spine(GO:0044308)
0.1 2.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 2.0 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.0 GO:0000815 ESCRT III complex(GO:0000815)
0.1 7.4 GO:0000502 proteasome complex(GO:0000502)
0.1 0.5 GO:0005914 spot adherens junction(GO:0005914)
0.1 1.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 1.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 2.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.7 GO:0034464 BBSome(GO:0034464)
0.1 0.6 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 1.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.4 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 2.9 GO:0016235 aggresome(GO:0016235)
0.1 3.7 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 7.9 GO:0005923 bicellular tight junction(GO:0005923)
0.1 0.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0140007 KICSTOR complex(GO:0140007)
0.0 2.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.1 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 1.4 GO:0001533 cornified envelope(GO:0001533)
0.0 2.1 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.3 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 1.7 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 7.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 3.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.0 1.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 2.4 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.4 GO:0005811 lipid droplet(GO:0005811)
0.0 1.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 4.2 GO:0030426 growth cone(GO:0030426)
0.0 44.3 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 1.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 4.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.9 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 1.4 GO:0031526 brush border membrane(GO:0031526)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
8.5 25.4 GO:0005186 pheromone activity(GO:0005186)
4.5 13.6 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
3.6 14.4 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
3.6 14.3 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632)
3.2 9.6 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
2.5 10.1 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
2.0 12.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
1.8 10.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.4 4.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
1.3 4.0 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
1.2 7.4 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
1.1 7.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.1 16.7 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
1.1 5.5 GO:0032810 sterol response element binding(GO:0032810)
1.0 7.3 GO:0099609 microtubule lateral binding(GO:0099609)
0.9 34.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.9 2.7 GO:0009918 sterol delta7 reductase activity(GO:0009918) 7-dehydrocholesterol reductase activity(GO:0047598)
0.9 2.6 GO:0019120 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
0.9 4.4 GO:0004533 exoribonuclease H activity(GO:0004533)
0.9 5.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.9 2.6 GO:0019150 D-ribulokinase activity(GO:0019150)
0.8 3.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.8 2.3 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.7 2.2 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867)
0.7 21.9 GO:0042056 chemoattractant activity(GO:0042056)
0.6 2.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.6 3.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.6 2.4 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.6 2.9 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901) sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590)
0.6 1.7 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.5 3.7 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.5 24.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.5 11.2 GO:0019825 oxygen binding(GO:0019825)
0.5 12.1 GO:0051787 misfolded protein binding(GO:0051787)
0.5 1.5 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.5 2.8 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.5 1.8 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.4 2.2 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.4 4.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.4 3.0 GO:0004556 alpha-amylase activity(GO:0004556)
0.4 3.8 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.4 1.2 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.4 9.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.4 4.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.4 2.5 GO:0016936 galactoside binding(GO:0016936)
0.3 2.7 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.3 1.6 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.3 9.7 GO:0001848 complement binding(GO:0001848)
0.3 1.6 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.3 1.6 GO:0016778 diphosphotransferase activity(GO:0016778)
0.3 1.2 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.3 1.2 GO:0097003 adipokinetic hormone receptor activity(GO:0097003) adipokinetic hormone binding(GO:0097004)
0.3 0.8 GO:0004995 tachykinin receptor activity(GO:0004995)
0.3 0.8 GO:0070002 glutamic-type peptidase activity(GO:0070002)
0.3 1.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.3 1.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.2 4.1 GO:0019865 immunoglobulin binding(GO:0019865)
0.2 1.9 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 0.7 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.2 2.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 3.2 GO:0070628 proteasome binding(GO:0070628)
0.2 1.6 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.2 1.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 5.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 4.8 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.2 1.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 1.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 3.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 0.7 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.2 8.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 2.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 0.5 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 2.5 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2 0.5 GO:0051747 cytosine C-5 DNA demethylase activity(GO:0051747)
0.2 1.0 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.2 3.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 1.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 0.7 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.2 2.4 GO:0070513 death domain binding(GO:0070513)
0.2 5.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 10.0 GO:0035004 phosphatidylinositol 3-kinase activity(GO:0035004)
0.1 1.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.0 GO:0001595 angiotensin receptor activity(GO:0001595)
0.1 0.6 GO:1990269 RNA polymerase II C-terminal domain binding(GO:0099122) RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.1 1.3 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 5.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.6 GO:0038100 nodal binding(GO:0038100)
0.1 12.1 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 0.5 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 16.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 6.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.5 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.9 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.7 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 1.2 GO:0015643 toxic substance binding(GO:0015643)
0.1 2.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.9 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 4.0 GO:0005504 fatty acid binding(GO:0005504)
0.1 7.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.4 GO:0034056 estrogen response element binding(GO:0034056)
0.1 1.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 3.2 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 1.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 2.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 4.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.6 GO:0051381 histamine receptor activity(GO:0004969) histamine binding(GO:0051381)
0.1 0.7 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 1.4 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.5 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 1.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 0.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.2 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.1 0.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.9 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 2.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.5 GO:0039706 co-receptor binding(GO:0039706) receptor antagonist activity(GO:0048019)
0.1 1.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.4 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.6 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.8 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0019809 spermidine binding(GO:0019809)
0.0 2.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.8 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 1.1 GO:0005521 lamin binding(GO:0005521)
0.0 2.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.6 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.3 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 1.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.2 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 1.9 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.9 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.7 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 6.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.7 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 1.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 1.2 GO:0042923 neuropeptide binding(GO:0042923)
0.0 2.4 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 1.4 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 2.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.1 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.3 GO:0043855 cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.9 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 1.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.3 GO:0070410 co-SMAD binding(GO:0070410)
0.0 2.1 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.5 GO:0003823 antigen binding(GO:0003823)
0.0 1.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0001784 phosphotyrosine residue binding(GO:0001784)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.4 13.4 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.2 7.8 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 5.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 6.2 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 4.1 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 6.8 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.6 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.1 2.1 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 2.3 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 0.9 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.1 1.3 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.1 1.5 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 2.2 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 6.7 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.7 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.1 2.2 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 2.5 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.5 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.0 0.8 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 1.0 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.3 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.5 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.3 PID_ARF_3PATHWAY Arf1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 27.7 REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM Genes involved in Bile acid and bile salt metabolism
0.6 9.9 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.5 10.8 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.3 8.3 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.3 7.3 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 6.9 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 2.5 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 5.9 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.2 4.7 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 2.3 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.2 14.1 REACTOME_PHASE_II_CONJUGATION Genes involved in Phase II conjugation
0.2 8.1 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 2.9 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 4.5 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 3.7 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 9.3 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.6 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 3.6 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 2.3 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 12.1 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 15.7 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 1.4 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 5.8 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.7 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 2.3 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.5 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.0 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.5 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 6.9 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 3.9 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 7.0 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.1 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.5 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.4 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.4 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 2.2 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 4.8 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 3.9 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 0.5 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.5 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.0 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.6 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.8 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 3.0 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.9 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 1.1 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.2 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.6 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.2 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.6 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.4 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.6 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.4 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling