Motif ID: Hoxa4

Z-value: 1.182


Transcription factors associated with Hoxa4:

Gene SymbolEntrez IDGene Name
Hoxa4 ENSMUSG00000000942.10 Hoxa4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hoxa4mm10_v2_chr6_-_52191695_52191753-0.521.3e-03Click!


Activity profile for motif Hoxa4.

activity profile for motif Hoxa4


Sorted Z-values histogram for motif Hoxa4

Sorted Z-values for motif Hoxa4



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_61674094 10.893 ENSMUST00000098040.3
Mup18
major urinary protein 18
chr4_-_60222580 10.048 ENSMUST00000095058.4
ENSMUST00000163931.1
Mup8

major urinary protein 8

chr4_-_61835185 9.753 ENSMUST00000082287.2
Mup5
major urinary protein 5
chr7_-_19699008 7.738 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
Apoe





apolipoprotein E





chr9_-_50555170 6.513 ENSMUST00000119103.1
Bco2
beta-carotene oxygenase 2
chr10_+_84756055 5.485 ENSMUST00000060397.6
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr15_+_10249560 5.338 ENSMUST00000134410.1
Prlr
prolactin receptor
chr2_+_70474923 5.158 ENSMUST00000100043.2
Sp5
trans-acting transcription factor 5
chr10_+_87859481 4.943 ENSMUST00000121952.1
Igf1
insulin-like growth factor 1
chr1_-_180193475 4.937 ENSMUST00000160482.1
ENSMUST00000170472.1
Adck3

aarF domain containing kinase 3

chr4_+_144893077 4.751 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr1_-_180193653 4.688 ENSMUST00000159914.1
Adck3
aarF domain containing kinase 3
chr7_+_51878967 4.537 ENSMUST00000051912.6
Gas2
growth arrest specific 2
chr5_-_87092546 4.413 ENSMUST00000132667.1
ENSMUST00000145617.1
ENSMUST00000094649.4
Ugt2b36


UDP glucuronosyltransferase 2 family, polypeptide B36


chr10_+_87859255 4.348 ENSMUST00000105300.2
Igf1
insulin-like growth factor 1
chr4_+_144892813 4.331 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr4_+_144893127 4.290 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr7_+_51879041 4.168 ENSMUST00000107591.2
Gas2
growth arrest specific 2
chr5_+_42067960 4.166 ENSMUST00000087332.4
Gm16223
predicted gene 16223
chr11_-_43836243 4.150 ENSMUST00000167574.1
Adra1b
adrenergic receptor, alpha 1b
chr10_+_87859062 4.136 ENSMUST00000095360.4
Igf1
insulin-like growth factor 1
chr3_+_115080965 3.902 ENSMUST00000051309.8
Olfm3
olfactomedin 3
chr12_-_57546121 3.375 ENSMUST00000044380.6
Foxa1
forkhead box A1
chr18_+_37435602 3.225 ENSMUST00000055495.5
Pcdhb12
protocadherin beta 12
chr4_-_134372529 3.187 ENSMUST00000030643.2
Extl1
exostoses (multiple)-like 1
chr16_+_37580137 3.096 ENSMUST00000160847.1
Hgd
homogentisate 1, 2-dioxygenase
chr6_+_124916863 2.924 ENSMUST00000069553.2
A230083G16Rik
RIKEN cDNA A230083G16 gene
chr13_+_58807884 2.806 ENSMUST00000079828.5
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr2_+_20737306 2.799 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr16_+_22857845 2.642 ENSMUST00000004574.7
ENSMUST00000178320.1
ENSMUST00000166487.2
Dnajb11


DnaJ (Hsp40) homolog, subfamily B, member 11


chr6_+_124304646 2.591 ENSMUST00000112541.2
ENSMUST00000032234.2
Cd163

CD163 antigen

chr2_-_5676046 2.560 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr1_+_74284930 2.553 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
Pnkd


paroxysmal nonkinesiogenic dyskinesia


chrM_+_5319 2.465 ENSMUST00000082402.1
mt-Co1
mitochondrially encoded cytochrome c oxidase I
chr2_+_109917639 2.449 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr11_-_116189542 2.405 ENSMUST00000148601.1
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr9_-_65885024 2.380 ENSMUST00000122410.1
ENSMUST00000117083.1
Trip4

thyroid hormone receptor interactor 4

chr11_+_94327984 2.331 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr12_+_59129757 2.298 ENSMUST00000069430.8
ENSMUST00000177370.1
Ctage5

CTAGE family, member 5

chr2_-_77519565 2.207 ENSMUST00000111830.2
Zfp385b
zinc finger protein 385B
chr10_+_53337686 2.191 ENSMUST00000046221.6
ENSMUST00000163319.1
Pln

phospholamban

chr6_+_43265582 2.173 ENSMUST00000031750.7
Arhgef5
Rho guanine nucleotide exchange factor (GEF) 5
chr10_-_24101951 2.165 ENSMUST00000170267.1
Taar8c
trace amine-associated receptor 8C
chr17_-_34862122 2.144 ENSMUST00000154526.1
Cfb
complement factor B
chr13_+_89540636 2.141 ENSMUST00000022108.7
Hapln1
hyaluronan and proteoglycan link protein 1
chr6_+_63255971 2.126 ENSMUST00000159561.1
ENSMUST00000095852.3
Grid2

glutamate receptor, ionotropic, delta 2

chr11_+_94328242 2.111 ENSMUST00000021227.5
Ankrd40
ankyrin repeat domain 40
chr7_-_34654342 2.076 ENSMUST00000108069.1
Kctd15
potassium channel tetramerisation domain containing 15
chr17_+_45734506 2.060 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr12_+_59129720 1.999 ENSMUST00000175912.1
ENSMUST00000176892.1
Ctage5

CTAGE family, member 5

chr18_+_58659443 1.986 ENSMUST00000025503.8
Isoc1
isochorismatase domain containing 1
chr19_+_31868754 1.900 ENSMUST00000075838.5
A1cf
APOBEC1 complementation factor
chr6_+_21986887 1.880 ENSMUST00000151315.1
Cped1
cadherin-like and PC-esterase domain containing 1
chr11_-_49114874 1.858 ENSMUST00000109201.1
Olfr1396
olfactory receptor 1396
chr3_+_89459118 1.845 ENSMUST00000029564.5
Pmvk
phosphomevalonate kinase
chr10_+_4611971 1.838 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1

estrogen receptor 1 (alpha)

chr5_+_139543889 1.834 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr1_+_165788681 1.759 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr1_+_132298606 1.723 ENSMUST00000046071.4
Klhdc8a
kelch domain containing 8A
chr17_+_24850515 1.723 ENSMUST00000154363.1
ENSMUST00000169200.1
Hagh

hydroxyacyl glutathione hydrolase

chr13_-_55362782 1.708 ENSMUST00000021940.7
Lman2
lectin, mannose-binding 2
chr17_+_24850654 1.686 ENSMUST00000130989.1
ENSMUST00000024974.9
Hagh

hydroxyacyl glutathione hydrolase

chr12_-_56535047 1.668 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr5_+_30814722 1.659 ENSMUST00000114724.1
Mapre3
microtubule-associated protein, RP/EB family, member 3
chr7_+_76411062 1.646 ENSMUST00000026854.3
ENSMUST00000107442.2
Agbl1

ATP/GTP binding protein-like 1

chr10_-_127121125 1.609 ENSMUST00000164259.1
ENSMUST00000080975.4
Os9

amplified in osteosarcoma

chr11_-_21572193 1.594 ENSMUST00000102874.4
Mdh1
malate dehydrogenase 1, NAD (soluble)
chr5_-_84417359 1.590 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr19_-_28967794 1.582 ENSMUST00000162110.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr18_+_37447641 1.578 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr8_-_67974567 1.578 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
Psd3


pleckstrin and Sec7 domain containing 3


chr16_-_36990449 1.572 ENSMUST00000075869.6
Fbxo40
F-box protein 40
chr12_+_55598917 1.564 ENSMUST00000051857.3
Insm2
insulinoma-associated 2
chr15_+_32920723 1.548 ENSMUST00000022871.5
Sdc2
syndecan 2
chr6_+_54040078 1.541 ENSMUST00000127323.2
Chn2
chimerin (chimaerin) 2
chr2_+_170731807 1.533 ENSMUST00000029075.4
Dok5
docking protein 5
chr2_-_119547194 1.513 ENSMUST00000133668.1
Exd1
exonuclease 3'-5' domain containing 1
chr7_+_131966446 1.503 ENSMUST00000045840.4
Gpr26
G protein-coupled receptor 26
chr1_+_165788746 1.487 ENSMUST00000161559.2
Cd247
CD247 antigen
chr1_-_138848576 1.440 ENSMUST00000112030.2
Lhx9
LIM homeobox protein 9
chr3_-_32491969 1.434 ENSMUST00000164954.1
Kcnmb3
potassium large conductance calcium-activated channel, subfamily M, beta member 3
chr8_+_22624019 1.422 ENSMUST00000033936.6
Dkk4
dickkopf homolog 4 (Xenopus laevis)
chr10_+_127420334 1.417 ENSMUST00000171434.1
R3hdm2
R3H domain containing 2
chr2_+_70563435 1.385 ENSMUST00000123330.1
Gad1
glutamate decarboxylase 1
chr14_-_30353468 1.363 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr6_-_138426735 1.349 ENSMUST00000162932.1
Lmo3
LIM domain only 3
chr3_+_86070915 1.348 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr8_+_47713266 1.334 ENSMUST00000180928.1
E030037K01Rik
RIKEN cDNA E030037K01 gene
chr1_-_67038824 1.330 ENSMUST00000119559.1
ENSMUST00000149996.1
ENSMUST00000027149.5
ENSMUST00000113979.3
Lancl1



LanC (bacterial lantibiotic synthetase component C)-like 1



chrM_+_10167 1.329 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr2_+_147187424 1.326 ENSMUST00000144411.1
6430503K07Rik
RIKEN cDNA 6430503K07 gene
chr5_-_146220901 1.322 ENSMUST00000169407.2
ENSMUST00000161331.1
ENSMUST00000159074.2
ENSMUST00000067837.3
Rnf6



ring finger protein (C3H2C3 type) 6



chr9_-_29412204 1.305 ENSMUST00000115237.1
Ntm
neurotrimin
chr19_+_8840519 1.302 ENSMUST00000086058.6
Bscl2
Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chrX_+_7579666 1.269 ENSMUST00000115740.1
ENSMUST00000115739.1
Foxp3

forkhead box P3

chr6_+_8949670 1.263 ENSMUST00000060369.3
Nxph1
neurexophilin 1
chr11_-_99337930 1.243 ENSMUST00000100482.2
Krt26
keratin 26
chrX_+_48623737 1.242 ENSMUST00000114936.1
Slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr1_-_5070281 1.221 ENSMUST00000147158.1
ENSMUST00000118000.1
Rgs20

regulator of G-protein signaling 20

chr14_-_50897456 1.190 ENSMUST00000170855.1
A930018M24Rik
RIKEN cDNA A930018M24 gene
chr5_+_105824511 1.139 ENSMUST00000055994.3
D830014E11Rik
RIKEN cDNA D830014E11 gene
chr3_-_88177671 1.120 ENSMUST00000181837.1
1700113A16Rik
RIKEN cDNA 1700113A16 gene
chr10_+_39612934 1.117 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr5_+_115235836 1.112 ENSMUST00000081497.6
Pop5
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr12_+_10390756 1.109 ENSMUST00000020947.5
Rdh14
retinol dehydrogenase 14 (all-trans and 9-cis)
chr19_+_24875679 1.087 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr3_+_5218546 1.081 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr17_+_39846958 1.078 ENSMUST00000182010.1
Gm26924
predicted gene, 26924
chr18_-_61014199 1.054 ENSMUST00000025520.8
Slc6a7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr1_-_190170671 1.023 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr13_+_63015167 1.023 ENSMUST00000021911.8
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chrX_-_106603677 1.023 ENSMUST00000113480.1
Cysltr1
cysteinyl leukotriene receptor 1
chr9_+_77636494 0.997 ENSMUST00000057781.7
Klhl31
kelch-like 31
chr5_-_32133045 0.995 ENSMUST00000031308.6
Gm10463
predicted gene 10463
chr4_+_99295900 0.994 ENSMUST00000094955.1
Gm12689
predicted gene 12689
chr15_-_37458523 0.992 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr4_-_116053825 0.978 ENSMUST00000030475.1
Nsun4
NOL1/NOP2/Sun domain family, member 4
chr19_-_20954202 0.975 ENSMUST00000039500.3
Tmc1
transmembrane channel-like gene family 1
chr8_+_46986913 0.969 ENSMUST00000039840.7
ENSMUST00000119686.1
Enpp6

ectonucleotide pyrophosphatase/phosphodiesterase 6

chr1_-_93478785 0.968 ENSMUST00000170883.1
Hdlbp
high density lipoprotein (HDL) binding protein
chr8_-_45294854 0.967 ENSMUST00000116473.2
Klkb1
kallikrein B, plasma 1
chr8_-_84937347 0.964 ENSMUST00000109741.2
ENSMUST00000119820.1
Mast1

microtubule associated serine/threonine kinase 1

chr19_+_11965817 0.954 ENSMUST00000025590.9
Osbp
oxysterol binding protein
chr2_+_83956398 0.954 ENSMUST00000178325.1
Gm13698
predicted gene 13698
chr15_+_55307743 0.916 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
Col14a1


collagen, type XIV, alpha 1


chr7_-_122101735 0.908 ENSMUST00000139456.1
ENSMUST00000106471.2
ENSMUST00000123296.1
ENSMUST00000033157.3
Ndufab1



NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1



chr16_-_64786321 0.905 ENSMUST00000052588.4
Zfp654
zinc finger protein 654
chr11_+_67200137 0.900 ENSMUST00000129018.1
Myh1
myosin, heavy polypeptide 1, skeletal muscle, adult
chr9_-_77399308 0.890 ENSMUST00000183878.1
RP23-264N13.2
RP23-264N13.2
chr11_-_99374895 0.886 ENSMUST00000006963.2
Krt28
keratin 28
chr16_-_22857514 0.882 ENSMUST00000004576.6
Tbccd1
TBCC domain containing 1
chr6_+_97210689 0.871 ENSMUST00000044681.6
Arl6ip5
ADP-ribosylation factor-like 6 interacting protein 5
chr13_+_63014934 0.862 ENSMUST00000091560.4
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr13_+_38204928 0.854 ENSMUST00000091641.5
ENSMUST00000178564.1
Snrnp48

small nuclear ribonucleoprotein 48 (U11/U12)

chr17_+_24470393 0.854 ENSMUST00000053024.6
Pgp
phosphoglycolate phosphatase
chr10_+_127421124 0.850 ENSMUST00000170336.1
R3hdm2
R3H domain containing 2
chr5_-_87699414 0.848 ENSMUST00000082370.5
Csn2
casein beta
chr15_-_99820072 0.831 ENSMUST00000109024.2
Lima1
LIM domain and actin binding 1
chr6_+_21986438 0.824 ENSMUST00000115382.1
Cped1
cadherin-like and PC-esterase domain containing 1
chr6_-_77979515 0.821 ENSMUST00000159626.1
ENSMUST00000075340.5
ENSMUST00000162273.1
Ctnna2


catenin (cadherin associated protein), alpha 2


chr4_+_11579647 0.813 ENSMUST00000180239.1
Fsbp
fibrinogen silencer binding protein
chr3_+_93442330 0.810 ENSMUST00000064257.5
Tchh
trichohyalin
chr18_-_31949571 0.810 ENSMUST00000064016.5
Gpr17
G protein-coupled receptor 17
chr4_+_150237694 0.810 ENSMUST00000141931.1
Eno1
enolase 1, alpha non-neuron
chrX_-_112698642 0.806 ENSMUST00000039887.3
Pof1b
premature ovarian failure 1B
chr8_-_67515606 0.802 ENSMUST00000032981.5
Gm9755
predicted pseudogene 9755
chr16_-_50432340 0.790 ENSMUST00000066037.6
ENSMUST00000089399.4
ENSMUST00000089404.3
ENSMUST00000114477.1
ENSMUST00000138166.1
Bbx




bobby sox homolog (Drosophila)




chr3_+_5218516 0.786 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr19_-_57197377 0.783 ENSMUST00000111546.1
Ablim1
actin-binding LIM protein 1
chr14_+_46832127 0.767 ENSMUST00000068532.8
Cgrrf1
cell growth regulator with ring finger domain 1
chr5_-_137531204 0.755 ENSMUST00000150063.2
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr3_+_41564880 0.730 ENSMUST00000168086.1
Phf17
PHD finger protein 17
chr15_+_28203726 0.714 ENSMUST00000067048.6
Dnah5
dynein, axonemal, heavy chain 5
chr3_-_80802789 0.698 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr18_-_20114767 0.689 ENSMUST00000038710.5
Dsc1
desmocollin 1
chr6_-_73138947 0.688 ENSMUST00000114038.1
Dnah6
dynein, axonemal, heavy chain 6
chr19_-_57197435 0.684 ENSMUST00000111550.1
Ablim1
actin-binding LIM protein 1
chr10_+_24076500 0.683 ENSMUST00000051133.5
Taar8a
trace amine-associated receptor 8A
chr10_+_127420867 0.659 ENSMUST00000064793.6
R3hdm2
R3H domain containing 2
chr3_+_94837702 0.644 ENSMUST00000107266.1
ENSMUST00000042402.5
ENSMUST00000107269.1
Pogz


pogo transposable element with ZNF domain


chr18_+_37489465 0.642 ENSMUST00000055949.2
Pcdhb18
protocadherin beta 18
chr7_-_120145286 0.640 ENSMUST00000033207.4
Zp2
zona pellucida glycoprotein 2
chr10_+_18469958 0.637 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chr11_-_100041547 0.625 ENSMUST00000056362.2
Krt34
keratin 34
chr6_+_29468068 0.625 ENSMUST00000143101.1
Atp6v1f
ATPase, H+ transporting, lysosomal V1 subunit F
chr5_-_137314175 0.624 ENSMUST00000024119.9
Trip6
thyroid hormone receptor interactor 6
chrX_+_150589907 0.619 ENSMUST00000080884.4
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr1_-_130729249 0.619 ENSMUST00000171479.1
Pfkfb2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr9_+_75775355 0.608 ENSMUST00000012281.7
Bmp5
bone morphogenetic protein 5
chr2_+_174327747 0.588 ENSMUST00000087871.4
Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr2_-_116065798 0.585 ENSMUST00000110907.1
ENSMUST00000110908.2
Meis2

Meis homeobox 2

chrX_+_136822671 0.577 ENSMUST00000033800.6
Plp1
proteolipid protein (myelin) 1
chr7_-_35056467 0.567 ENSMUST00000130491.1
Cebpg
CCAAT/enhancer binding protein (C/EBP), gamma
chr16_-_76373827 0.564 ENSMUST00000121927.1
Nrip1
nuclear receptor interacting protein 1
chr3_+_94837533 0.563 ENSMUST00000107270.2
Pogz
pogo transposable element with ZNF domain
chr12_+_55384222 0.555 ENSMUST00000163070.1
Psma6
proteasome (prosome, macropain) subunit, alpha type 6
chr19_-_38224096 0.553 ENSMUST00000067167.5
Fra10ac1
FRA10AC1 homolog (human)
chr1_-_92518515 0.546 ENSMUST00000062353.4
Olfr1414
olfactory receptor 1414
chr16_+_17331371 0.538 ENSMUST00000023450.6
ENSMUST00000161034.1
Serpind1

serine (or cysteine) peptidase inhibitor, clade D, member 1

chr1_+_180111339 0.525 ENSMUST00000145181.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr9_-_37669170 0.521 ENSMUST00000011262.2
Panx3
pannexin 3
chr18_-_79109391 0.518 ENSMUST00000025430.8
ENSMUST00000161465.2
Setbp1

SET binding protein 1

chr18_+_37355271 0.516 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr17_-_43667015 0.515 ENSMUST00000024705.4
Slc25a27
solute carrier family 25, member 27
chr15_-_37459327 0.511 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr1_-_110977366 0.506 ENSMUST00000094626.3
Cdh19
cadherin 19, type 2
chr10_+_127421208 0.499 ENSMUST00000168780.1
R3hdm2
R3H domain containing 2
chr1_-_163313661 0.498 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
Prrx1


paired related homeobox 1


chr2_-_93849679 0.498 ENSMUST00000068513.4
ENSMUST00000041593.8
ENSMUST00000130077.1
Accs


1-aminocyclopropane-1-carboxylate synthase (non-functional)


chr11_-_33203588 0.496 ENSMUST00000037746.6
Tlx3
T cell leukemia, homeobox 3
chr3_-_146781351 0.494 ENSMUST00000005164.7
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr5_-_122614445 0.494 ENSMUST00000127220.1
ENSMUST00000031426.7
Ift81

intraflagellar transport 81

chrX_-_48513518 0.492 ENSMUST00000114945.2
ENSMUST00000037349.7
Aifm1

apoptosis-inducing factor, mitochondrion-associated 1

chr15_-_82912134 0.492 ENSMUST00000048966.5
ENSMUST00000109510.2
Tcf20

transcription factor 20

chr6_+_106118924 0.485 ENSMUST00000079416.5
Cntn4
contactin 4
chr6_+_29467718 0.475 ENSMUST00000004396.6
Atp6v1f
ATPase, H+ transporting, lysosomal V1 subunit F
chr12_-_31713873 0.471 ENSMUST00000057783.4
ENSMUST00000174480.2
ENSMUST00000176710.1
Gpr22


G protein-coupled receptor 22


chr3_+_5218589 0.468 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr5_-_137530990 0.451 ENSMUST00000132525.1
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr8_+_106059562 0.451 ENSMUST00000109308.1
Nfatc3
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 GO:1905890 cellular response to very-low-density lipoprotein particle stimulus(GO:0090731) negative regulation of presynaptic membrane organization(GO:1901630) regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002) regulation of heparan sulfate binding(GO:1905853) positive regulation of heparan sulfate binding(GO:1905855) regulation of heparan sulfate proteoglycan binding(GO:1905858) positive regulation of heparan sulfate proteoglycan binding(GO:1905860) regulation of cellular response to very-low-density lipoprotein particle stimulus(GO:1905890)
2.2 13.4 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
1.7 3.4 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
1.4 4.1 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
1.1 5.5 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.9 5.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.8 13.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.8 2.4 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.7 6.5 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.7 2.8 GO:0099551 trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.6 3.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.6 6.0 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.6 1.7 GO:0021759 globus pallidus development(GO:0021759)
0.5 2.2 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.5 1.8 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.4 1.3 GO:0045077 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment(GO:0002362) peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465) negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.4 1.7 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.4 2.4 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.3 1.0 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.3 1.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.3 1.8 GO:0060011 Sertoli cell proliferation(GO:0060011) prostate epithelial cord elongation(GO:0060523)
0.3 1.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.3 2.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 1.6 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.3 2.0 GO:0009249 protein lipoylation(GO:0009249)
0.2 1.0 GO:0060005 vestibular reflex(GO:0060005)
0.2 1.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 1.6 GO:0006108 malate metabolic process(GO:0006108)
0.2 1.3 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.2 2.2 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.2 0.9 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.2 0.6 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2 1.8 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.2 1.4 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.2 1.4 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 1.0 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.2 1.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.9 GO:0051661 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.2 2.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 0.8 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.2 0.8 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.2 1.0 GO:0042256 mature ribosome assembly(GO:0042256)
0.2 0.6 GO:0021502 neural fold elevation formation(GO:0021502)
0.1 2.9 GO:0060134 prepulse inhibition(GO:0060134)
0.1 0.6 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 2.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.4 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.5 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 1.0 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.4 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.6 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.3 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.3 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.1 2.6 GO:0016556 mRNA modification(GO:0016556)
0.1 1.2 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 1.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.4 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1 1.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.6 GO:0060468 prevention of polyspermy(GO:0060468)
0.1 0.6 GO:0097475 motor neuron migration(GO:0097475)
0.1 1.5 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.3 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.3 GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.1 0.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 1.2 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.1 GO:0035844 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.1 3.9 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 1.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.4 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.4 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.1 1.9 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 3.2 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.6 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.4 GO:0035166 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) post-embryonic hemopoiesis(GO:0035166)
0.1 0.8 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.3 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.1 0.2 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.1 0.5 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.1 1.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 2.4 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 1.3 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.1 2.6 GO:0006953 acute-phase response(GO:0006953)
0.1 0.2 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.1 1.0 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.8 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.7 GO:1902004 positive regulation of amyloid-beta formation(GO:1902004)
0.0 0.7 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 2.1 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.1 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 1.1 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 1.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 6.0 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.1 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.0 1.1 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.5 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.5 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.4 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.9 GO:0061050 regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.0 3.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 1.0 GO:0007097 nuclear migration(GO:0007097)
0.0 1.1 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.4 GO:0045109 intermediate filament organization(GO:0045109)
0.0 2.7 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.5 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.8 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 1.4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.7 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 3.2 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.7 GO:0003341 cilium movement(GO:0003341)
0.0 0.7 GO:0008542 visual learning(GO:0008542)
0.0 0.3 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.7 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
1.5 13.4 GO:0042567 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) insulin-like growth factor ternary complex(GO:0042567)
0.6 2.4 GO:0099053 activating signal cointegrator 1 complex(GO:0099053)
0.4 3.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.3 1.9 GO:0045293 mRNA editing complex(GO:0045293)
0.3 1.5 GO:1990923 PET complex(GO:1990923)
0.3 1.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 0.6 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 1.6 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 2.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 1.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 2.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.7 GO:0106003 amyloid-beta complex(GO:0106003)
0.1 1.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 2.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 3.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 4.2 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.4 GO:1990131 GATOR1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 2.5 GO:0098878 neurotransmitter receptor complex(GO:0098878)
0.1 1.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.3 GO:0032437 cuticular plate(GO:0032437)
0.1 0.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 1.5 GO:0030057 desmosome(GO:0030057)
0.0 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.0 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 3.6 GO:0030315 T-tubule(GO:0030315)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 2.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 2.2 GO:0070469 respiratory chain(GO:0070469)
0.0 1.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834) GTPase complex(GO:1905360)
0.0 0.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 2.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.5 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 3.8 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 3.8 GO:0042641 actomyosin(GO:0042641)
0.0 1.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 3.8 GO:0001650 fibrillar center(GO:0001650)
0.0 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 2.0 GO:0005882 intermediate filament(GO:0005882)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.1 GO:0043209 myelin sheath(GO:0043209)
0.0 1.4 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 1.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 GO:0046911 metal chelating activity(GO:0046911)
1.9 13.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.1 5.3 GO:0004925 prolactin receptor activity(GO:0004925)
1.1 3.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
1.0 4.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.9 2.8 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.6 1.8 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.6 6.0 GO:0004462 hydroxyacylglutathione hydrolase activity(GO:0004416) lactoylglutathione lyase activity(GO:0004462)
0.5 1.6 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.4 2.4 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.4 1.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.4 2.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.4 9.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.3 1.0 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.3 9.3 GO:0005550 pheromone binding(GO:0005550)
0.3 2.7 GO:0001594 trace-amine receptor activity(GO:0001594)
0.3 1.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.2 0.9 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.2 0.6 GO:0032190 acrosin binding(GO:0032190)
0.2 1.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 1.4 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.2 5.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 1.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 2.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 4.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 0.4 GO:0022850 serotonin-gated cation-selective channel activity(GO:0022850)
0.1 1.1 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.1 1.0 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.3 GO:0001587 Gq/11-coupled serotonin receptor activity(GO:0001587)
0.1 1.3 GO:0051525 NFAT protein binding(GO:0051525)
0.1 2.7 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1 0.5 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 1.0 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 1.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.4 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 2.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 3.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 2.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.7 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.7 GO:0005537 mannose binding(GO:0005537)
0.1 0.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.8 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 2.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 1.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 1.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 1.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 3.2 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 1.1 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.0 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.8 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 1.3 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 1.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 2.2 GO:0002039 p53 binding(GO:0002039)
0.0 2.6 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.5 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.8 GO:0005549 odorant binding(GO:0005549)
0.0 6.0 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.3 GO:0004750 gluconolactonase activity(GO:0004341) ribulose-phosphate 3-epimerase activity(GO:0004750) ribose-5-phosphate isomerase activity(GO:0004751) sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity(GO:0004801)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 15.3 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.2 12.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 8.7 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 5.3 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 4.3 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 4.4 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 4.8 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.1 3.2 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 4.4 PID_SHP2_PATHWAY SHP2 signaling
0.1 1.2 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.1 1.6 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 6.3 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.5 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 3.9 PID_P73PATHWAY p73 transcription factor network
0.1 2.1 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 0.7 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 1.5 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 2.5 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.7 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.8 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 1.5 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.8 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.5 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.8 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.7 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 3.2 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3 8.7 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 5.3 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.2 2.1 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.2 2.3 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 4.5 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.4 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 3.9 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.5 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.7 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 2.1 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.8 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.1 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.9 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.4 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.6 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 1.8 REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 1.0 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 1.1 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 1.4 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 1.2 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.0 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 1.0 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.4 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 3.1 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.9 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 2.1 REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.4 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation