Motif ID: Hoxb13

Z-value: 1.566


Transcription factors associated with Hoxb13:

Gene SymbolEntrez IDGene Name
Hoxb13 ENSMUSG00000049604.3 Hoxb13

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hoxb13mm10_v2_chr11_+_96194299_96194316-0.363.0e-02Click!


Activity profile for motif Hoxb13.

activity profile for motif Hoxb13


Sorted Z-values histogram for motif Hoxb13

Sorted Z-values for motif Hoxb13



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb13

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_24576297 21.595 ENSMUST00000033953.7
ENSMUST00000121992.1
Ido2

indoleamine 2,3-dioxygenase 2

chr5_-_146009598 20.819 ENSMUST00000138870.1
ENSMUST00000068317.6
Cyp3a25

cytochrome P450, family 3, subfamily a, polypeptide 25

chr5_+_146079254 20.341 ENSMUST00000035571.8
Cyp3a59
cytochrome P450, family 3, subfamily a, polypeptide 59
chr4_-_61674094 12.842 ENSMUST00000098040.3
Mup18
major urinary protein 18
chr19_-_8405060 11.417 ENSMUST00000064507.5
ENSMUST00000120540.1
ENSMUST00000096269.4
Slc22a30


solute carrier family 22, member 30


chr4_-_61303802 11.364 ENSMUST00000125461.1
Mup14
major urinary protein 14
chr19_+_40089688 11.361 ENSMUST00000068094.6
ENSMUST00000080171.2
Cyp2c50

cytochrome P450, family 2, subfamily c, polypeptide 50

chr4_-_61519467 10.972 ENSMUST00000095051.5
ENSMUST00000107483.1
Mup16

major urinary protein 16

chr4_-_61303998 10.686 ENSMUST00000071005.8
ENSMUST00000075206.5
Mup14

major urinary protein 14

chr4_-_61439743 10.460 ENSMUST00000095049.4
Mup15
major urinary protein 15
chr19_+_39287074 10.370 ENSMUST00000003137.8
Cyp2c29
cytochrome P450, family 2, subfamily c, polypeptide 29
chr4_-_61228271 10.347 ENSMUST00000072678.5
ENSMUST00000098042.3
Mup13

major urinary protein 13

chr4_-_60070411 10.143 ENSMUST00000079697.3
ENSMUST00000125282.1
ENSMUST00000166098.1
Mup7


major urinary protein 7


chr4_-_60662358 9.681 ENSMUST00000084544.4
ENSMUST00000098046.3
Mup11

major urinary protein 11

chr19_+_39992424 9.527 ENSMUST00000049178.2
Cyp2c37
cytochrome P450, family 2. subfamily c, polypeptide 37
chr4_-_61595871 9.313 ENSMUST00000107484.1
Mup17
major urinary protein 17
chr4_-_60501903 9.168 ENSMUST00000084548.4
ENSMUST00000103012.3
ENSMUST00000107499.3
Mup1


major urinary protein 1


chr6_+_41302265 9.051 ENSMUST00000031913.4
Try4
trypsin 4
chr4_-_60139857 8.985 ENSMUST00000107490.4
ENSMUST00000074700.2
Mup2

major urinary protein 2

chr1_-_121332545 8.879 ENSMUST00000161068.1
Insig2
insulin induced gene 2
chr12_-_104153846 8.856 ENSMUST00000085050.3
Serpina3c
serine (or cysteine) peptidase inhibitor, clade A, member 3C
chr13_-_23914998 8.610 ENSMUST00000021769.8
ENSMUST00000110407.2
Slc17a4

solute carrier family 17 (sodium phosphate), member 4

chr4_-_60741275 8.368 ENSMUST00000117932.1
Mup12
major urinary protein 12
chr4_-_60222580 8.312 ENSMUST00000095058.4
ENSMUST00000163931.1
Mup8

major urinary protein 8

chr4_-_60421933 8.293 ENSMUST00000107506.2
ENSMUST00000122381.1
ENSMUST00000118759.1
ENSMUST00000122177.1
Mup9



major urinary protein 9



chr4_-_60582152 8.068 ENSMUST00000098047.2
Mup10
major urinary protein 10
chr15_-_75431745 8.048 ENSMUST00000096397.1
9030619P08Rik
RIKEN cDNA 9030619P08 gene
chr8_-_93279717 7.922 ENSMUST00000034178.8
Ces1f
carboxylesterase 1F
chr7_+_26808880 7.277 ENSMUST00000040944.7
Cyp2g1
cytochrome P450, family 2, subfamily g, polypeptide 1
chr6_-_41314700 7.120 ENSMUST00000064324.5
Try5
trypsin 5
chr5_-_87337165 7.025 ENSMUST00000031195.2
Ugt2a3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr1_-_121332571 6.965 ENSMUST00000071064.6
Insig2
insulin induced gene 2
chr13_+_4434306 6.836 ENSMUST00000021630.8
Akr1c6
aldo-keto reductase family 1, member C6
chr1_-_150465563 6.815 ENSMUST00000164600.1
ENSMUST00000111902.2
ENSMUST00000111901.2
ENSMUST00000006171.9
Prg4



proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)



chr6_-_85869128 6.757 ENSMUST00000045008.7
Cml2
camello-like 2
chr19_+_12633303 6.753 ENSMUST00000044976.5
Glyat
glycine-N-acyltransferase
chr19_-_7802578 6.722 ENSMUST00000120522.1
ENSMUST00000065634.7
Slc22a26

solute carrier family 22 (organic cation transporter), member 26

chr19_+_12633507 6.449 ENSMUST00000119960.1
Glyat
glycine-N-acyltransferase
chr17_-_31144271 6.355 ENSMUST00000024826.7
Tff2
trefoil factor 2 (spasmolytic protein 1)
chr15_-_77411034 6.203 ENSMUST00000089452.5
ENSMUST00000081776.3
Apol9a

apolipoprotein L 9a

chr16_+_91269759 5.997 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr7_+_44207307 5.736 ENSMUST00000077354.4
Klk1b4
kallikrein 1-related pepidase b4
chr1_-_193264006 5.710 ENSMUST00000161737.1
Hsd11b1
hydroxysteroid 11-beta dehydrogenase 1
chr7_+_132610620 5.689 ENSMUST00000033241.5
Lhpp
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr8_+_45069137 5.688 ENSMUST00000067984.7
Mtnr1a
melatonin receptor 1A
chr4_-_62054112 5.684 ENSMUST00000074018.3
Mup20
major urinary protein 20
chr4_-_115496129 5.559 ENSMUST00000030487.2
Cyp4a14
cytochrome P450, family 4, subfamily a, polypeptide 14
chr15_+_77729091 5.535 ENSMUST00000109775.2
Apol9b
apolipoprotein L 9b
chr15_+_6445320 5.355 ENSMUST00000022749.9
C9
complement component 9
chr13_-_41847482 5.017 ENSMUST00000072012.3
Adtrp
androgen dependent TFPI regulating protein
chr7_+_44198191 4.959 ENSMUST00000085450.2
Klk1b3
kallikrein 1-related peptidase b3
chr4_+_115518264 4.882 ENSMUST00000058785.3
ENSMUST00000094886.3
Cyp4a10

cytochrome P450, family 4, subfamily a, polypeptide 10

chr13_-_41847599 4.877 ENSMUST00000179758.1
Adtrp
androgen dependent TFPI regulating protein
chr5_-_87091150 4.856 ENSMUST00000154455.1
Ugt2b36
UDP glucuronosyltransferase 2 family, polypeptide B36
chr4_-_49383576 4.747 ENSMUST00000107698.1
Acnat2
acyl-coenzyme A amino acid N-acyltransferase 2
chr3_+_129836729 4.672 ENSMUST00000077918.5
Cfi
complement component factor i
chr8_+_70083509 4.663 ENSMUST00000007738.9
Hapln4
hyaluronan and proteoglycan link protein 4
chr1_+_88095054 4.592 ENSMUST00000150634.1
ENSMUST00000058237.7
Ugt1a7c

UDP glucuronosyltransferase 1 family, polypeptide A7C

chr17_+_31433054 4.492 ENSMUST00000136384.1
Pde9a
phosphodiesterase 9A
chr4_-_108118504 4.460 ENSMUST00000149106.1
Scp2
sterol carrier protein 2, liver
chr19_-_8218832 4.410 ENSMUST00000113298.2
Slc22a29
solute carrier family 22. member 29
chr9_-_51328898 4.405 ENSMUST00000039959.4
1810046K07Rik
RIKEN cDNA 1810046K07 gene
chr4_+_20007938 4.351 ENSMUST00000125799.1
ENSMUST00000121491.1
Ttpa

tocopherol (alpha) transfer protein

chr4_+_141368116 4.276 ENSMUST00000006380.4
Fam131c
family with sequence similarity 131, member C
chrM_+_3906 4.211 ENSMUST00000082396.1
mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr11_-_113710017 4.188 ENSMUST00000018871.1
Cpsf4l
cleavage and polyadenylation specific factor 4-like
chr10_+_84756055 4.183 ENSMUST00000060397.6
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr1_+_13668739 4.163 ENSMUST00000088542.3
Xkr9
X Kell blood group precursor related family member 9 homolog
chr1_-_130661584 4.141 ENSMUST00000137276.2
C4bp
complement component 4 binding protein
chr7_-_68275098 4.116 ENSMUST00000135564.1
Gm16157
predicted gene 16157
chr7_-_12998172 4.011 ENSMUST00000120903.1
Slc27a5
solute carrier family 27 (fatty acid transporter), member 5
chr1_-_130661613 4.009 ENSMUST00000027657.7
C4bp
complement component 4 binding protein
chr5_-_145879857 3.995 ENSMUST00000035918.7
Cyp3a11
cytochrome P450, family 3, subfamily a, polypeptide 11
chr7_-_139582790 3.963 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr11_-_11898092 3.942 ENSMUST00000178704.1
Ddc
dopa decarboxylase
chr14_-_51913393 3.925 ENSMUST00000004673.7
ENSMUST00000111632.3
Ndrg2

N-myc downstream regulated gene 2

chr14_+_65969714 3.890 ENSMUST00000153460.1
Clu
clusterin
chr16_+_22951072 3.871 ENSMUST00000023590.8
Hrg
histidine-rich glycoprotein
chr6_+_42245907 3.848 ENSMUST00000031897.5
Gstk1
glutathione S-transferase kappa 1
chr8_-_109579056 3.844 ENSMUST00000074898.6
Hp
haptoglobin
chr7_+_119607014 3.831 ENSMUST00000126367.1
Acsm1
acyl-CoA synthetase medium-chain family member 1
chr3_+_19985612 3.820 ENSMUST00000172860.1
Cp
ceruloplasmin
chr5_+_114175889 3.711 ENSMUST00000146841.1
Acacb
acetyl-Coenzyme A carboxylase beta
chr5_+_137981512 3.646 ENSMUST00000035390.5
Azgp1
alpha-2-glycoprotein 1, zinc
chrX_+_59999436 3.554 ENSMUST00000033477.4
F9
coagulation factor IX
chr8_+_95352258 3.461 ENSMUST00000034243.5
Mmp15
matrix metallopeptidase 15
chr6_+_41354105 3.447 ENSMUST00000072103.5
Try10
trypsin 10
chr19_-_11081088 3.416 ENSMUST00000025636.6
Ms4a8a
membrane-spanning 4-domains, subfamily A, member 8A
chr14_+_65968483 3.405 ENSMUST00000022616.6
Clu
clusterin
chr8_-_117671526 3.350 ENSMUST00000037955.7
Sdr42e1
short chain dehydrogenase/reductase family 42E, member 1
chr8_-_105933832 3.341 ENSMUST00000034368.6
Ctrl
chymotrypsin-like
chr4_-_108217897 3.331 ENSMUST00000106690.1
ENSMUST00000043793.6
Zyg11a

zyg-11 family member A, cell cycle regulator

chr14_-_47189406 3.301 ENSMUST00000089959.6
Gch1
GTP cyclohydrolase 1
chr13_-_41847626 3.289 ENSMUST00000121404.1
Adtrp
androgen dependent TFPI regulating protein
chr16_+_56204313 3.216 ENSMUST00000160116.1
ENSMUST00000069936.7
Impg2

interphotoreceptor matrix proteoglycan 2

chr6_-_85933379 3.214 ENSMUST00000162660.1
Nat8b
N-acetyltransferase 8B
chr5_+_114923234 3.208 ENSMUST00000031540.4
ENSMUST00000112143.3
Oasl1

2'-5' oligoadenylate synthetase-like 1

chrX_-_100594860 3.194 ENSMUST00000053373.1
P2ry4
pyrimidinergic receptor P2Y, G-protein coupled, 4
chr4_+_144893127 3.149 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr5_-_113081579 3.117 ENSMUST00000131708.1
ENSMUST00000117143.1
ENSMUST00000119627.1
Crybb3


crystallin, beta B3


chr16_-_23988852 3.082 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chr4_+_99030946 3.070 ENSMUST00000030280.6
Angptl3
angiopoietin-like 3
chr5_-_87424201 3.065 ENSMUST00000072818.5
Ugt2b38
UDP glucuronosyltransferase 2 family, polypeptide B38
chr12_-_98577940 3.034 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr12_+_108334341 3.028 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr10_-_107123585 3.025 ENSMUST00000165067.1
ENSMUST00000044668.4
Acss3

acyl-CoA synthetase short-chain family member 3

chr1_+_160978576 3.007 ENSMUST00000064725.5
Serpinc1
serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
chr8_-_25038875 2.979 ENSMUST00000084031.4
Htra4
HtrA serine peptidase 4
chr19_+_30232921 2.972 ENSMUST00000025797.5
Mbl2
mannose-binding lectin (protein C) 2
chr2_-_32451396 2.946 ENSMUST00000028160.8
ENSMUST00000113310.2
Slc25a25

solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25

chr19_-_39649046 2.926 ENSMUST00000067328.6
Cyp2c67
cytochrome P450, family 2, subfamily c, polypeptide 67
chr11_+_94211431 2.907 ENSMUST00000041589.5
Tob1
transducer of ErbB-2.1
chr8_-_5105232 2.903 ENSMUST00000023835.1
Slc10a2
solute carrier family 10, member 2
chr5_-_45450221 2.901 ENSMUST00000015950.5
Qdpr
quinoid dihydropteridine reductase
chr9_+_107340593 2.894 ENSMUST00000042581.2
6430571L13Rik
RIKEN cDNA 6430571L13 gene
chr3_+_62338344 2.883 ENSMUST00000079300.6
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr8_-_41215146 2.848 ENSMUST00000034003.4
Fgl1
fibrinogen-like protein 1
chr6_+_124512615 2.837 ENSMUST00000068593.7
C1ra
complement component 1, r subcomponent A
chr2_+_25054396 2.824 ENSMUST00000102931.4
ENSMUST00000074422.7
ENSMUST00000132172.1
ENSMUST00000114388.1
ENSMUST00000114386.1
Nsmf




NMDA receptor synaptonuclear signaling and neuronal migration factor




chr7_+_127800604 2.816 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr11_-_73324616 2.807 ENSMUST00000021119.2
Aspa
aspartoacylase
chr5_-_77095225 2.802 ENSMUST00000120827.2
ENSMUST00000113453.2
Hopx

HOP homeobox

chr5_-_87538188 2.802 ENSMUST00000031199.4
Sult1b1
sulfotransferase family 1B, member 1
chr4_+_102570065 2.768 ENSMUST00000097950.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr11_+_97029925 2.735 ENSMUST00000021249.4
Scrn2
secernin 2
chr3_+_19957088 2.727 ENSMUST00000108328.1
Cp
ceruloplasmin
chr14_-_68533689 2.720 ENSMUST00000022640.7
Adam7
a disintegrin and metallopeptidase domain 7
chr9_-_50555170 2.691 ENSMUST00000119103.1
Bco2
beta-carotene oxygenase 2
chr10_-_115362191 2.669 ENSMUST00000092170.5
Tmem19
transmembrane protein 19
chr18_-_38209762 2.666 ENSMUST00000057185.6
Pcdh1
protocadherin 1
chr5_-_87569023 2.651 ENSMUST00000113314.2
Sult1d1
sulfotransferase family 1D, member 1
chr6_+_124304646 2.649 ENSMUST00000112541.2
ENSMUST00000032234.2
Cd163

CD163 antigen

chr9_-_44799179 2.641 ENSMUST00000114705.1
ENSMUST00000002100.7
Tmem25

transmembrane protein 25

chr13_+_34734837 2.639 ENSMUST00000039605.6
Fam50b
family with sequence similarity 50, member B
chr15_+_31224371 2.634 ENSMUST00000044524.9
Dap
death-associated protein
chr16_-_31314804 2.598 ENSMUST00000115230.1
ENSMUST00000130560.1
Apod

apolipoprotein D

chr18_-_3281752 2.593 ENSMUST00000140332.1
ENSMUST00000147138.1
Crem

cAMP responsive element modulator

chr5_-_87591582 2.592 ENSMUST00000031201.7
Sult1e1
sulfotransferase family 1E, member 1
chr13_+_24845122 2.580 ENSMUST00000006893.8
D130043K22Rik
RIKEN cDNA D130043K22 gene
chr1_-_162866502 2.567 ENSMUST00000046049.7
Fmo1
flavin containing monooxygenase 1
chr15_-_39857459 2.535 ENSMUST00000022915.3
ENSMUST00000110306.1
Dpys

dihydropyrimidinase

chr3_+_19957037 2.532 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr11_-_116189542 2.509 ENSMUST00000148601.1
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr2_-_18048784 2.507 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr11_-_4118778 2.497 ENSMUST00000003681.7
Sec14l2
SEC14-like 2 (S. cerevisiae)
chr16_+_13940630 2.490 ENSMUST00000141971.1
ENSMUST00000124947.1
ENSMUST00000023360.7
ENSMUST00000143697.1
Mpv17l



Mpv17 transgene, kidney disease mutant-like



chr3_+_19957240 2.487 ENSMUST00000108325.2
Cp
ceruloplasmin
chr3_+_142701067 2.478 ENSMUST00000044392.4
Ccbl2
cysteine conjugate-beta lyase 2
chr15_-_31453564 2.474 ENSMUST00000110408.1
Ropn1l
ropporin 1-like
chr7_-_12998140 2.469 ENSMUST00000032539.7
Slc27a5
solute carrier family 27 (fatty acid transporter), member 5
chr11_+_101665541 2.467 ENSMUST00000039388.2
Arl4d
ADP-ribosylation factor-like 4D
chr17_-_91092715 2.459 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
Nrxn1


neurexin I


chr3_+_138313279 2.430 ENSMUST00000013455.6
ENSMUST00000106247.1
Adh6a

alcohol dehydrogenase 6A (class V)

chr2_-_91195035 2.417 ENSMUST00000111356.1
Nr1h3
nuclear receptor subfamily 1, group H, member 3
chr15_-_77399086 2.414 ENSMUST00000175919.1
ENSMUST00000176074.1
Apol7a

apolipoprotein L 7a

chr9_-_106247730 2.407 ENSMUST00000112524.2
ENSMUST00000074082.6
Alas1

aminolevulinic acid synthase 1

chr14_-_37048957 2.400 ENSMUST00000022338.5
Rgr
retinal G protein coupled receptor
chr5_-_45450143 2.398 ENSMUST00000154962.1
Qdpr
quinoid dihydropteridine reductase
chr6_+_71199827 2.393 ENSMUST00000067492.7
Fabp1
fatty acid binding protein 1, liver
chr16_-_46155077 2.387 ENSMUST00000059524.5
Gm4737
predicted gene 4737
chr10_+_41490436 2.379 ENSMUST00000105507.3
Ppil6
peptidylprolyl isomerase (cyclophilin)-like 6
chr1_-_97128249 2.375 ENSMUST00000027569.7
Slco6c1
solute carrier organic anion transporter family, member 6c1
chr2_-_91195097 2.356 ENSMUST00000002177.2
ENSMUST00000111354.1
Nr1h3

nuclear receptor subfamily 1, group H, member 3

chr5_-_88526496 2.351 ENSMUST00000164073.1
Igj
immunoglobulin joining chain
chr8_-_105943382 2.345 ENSMUST00000038896.7
Lcat
lecithin cholesterol acyltransferase
chr1_-_69108039 2.342 ENSMUST00000121473.1
Erbb4
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
chr2_-_91236877 2.335 ENSMUST00000111352.1
Ddb2
damage specific DNA binding protein 2
chr10_+_23851454 2.334 ENSMUST00000020190.7
Vnn3
vanin 3
chr2_-_86347764 2.328 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr11_-_110095937 2.327 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr17_+_34197715 2.326 ENSMUST00000173441.1
ENSMUST00000025196.8
Psmb8

proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)

chr2_+_177508570 2.304 ENSMUST00000108940.2
Gm14403
predicted gene 14403
chr2_-_144550777 2.304 ENSMUST00000028915.5
Rbbp9
retinoblastoma binding protein 9
chr15_-_34495180 2.286 ENSMUST00000022946.5
Hrsp12
heat-responsive protein 12
chr4_+_20008357 2.285 ENSMUST00000117632.1
ENSMUST00000098244.1
Ttpa

tocopherol (alpha) transfer protein

chr18_-_31820413 2.280 ENSMUST00000165131.2
Gm6665
predicted gene 6665
chr1_+_185332143 2.262 ENSMUST00000027916.6
ENSMUST00000151769.1
ENSMUST00000110965.1
Bpnt1


bisphosphate 3'-nucleotidase 1


chrX_-_75380041 2.257 ENSMUST00000114085.2
F8
coagulation factor VIII
chr8_-_94696223 2.241 ENSMUST00000034227.4
Pllp
plasma membrane proteolipid
chr9_+_7692086 2.204 ENSMUST00000018767.7
Mmp7
matrix metallopeptidase 7
chr8_+_45507768 2.169 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr1_-_36244245 2.162 ENSMUST00000046875.7
Uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr2_-_69342600 2.155 ENSMUST00000102709.1
ENSMUST00000102710.3
ENSMUST00000180142.1
Abcb11


ATP-binding cassette, sub-family B (MDR/TAP), member 11


chr8_+_45069374 2.154 ENSMUST00000130141.1
Mtnr1a
melatonin receptor 1A
chr12_-_103657095 2.149 ENSMUST00000152517.1
Serpina6
serine (or cysteine) peptidase inhibitor, clade A, member 6
chr15_+_32920723 2.141 ENSMUST00000022871.5
Sdc2
syndecan 2
chr11_-_21371143 2.133 ENSMUST00000060895.5
Ugp2
UDP-glucose pyrophosphorylase 2
chr6_+_40628824 2.129 ENSMUST00000071535.6
Mgam
maltase-glucoamylase
chrX_+_139563316 2.123 ENSMUST00000113027.1
Rnf128
ring finger protein 128
chr7_-_80403315 2.117 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr12_+_85288591 2.112 ENSMUST00000059341.4
Zc2hc1c
zinc finger, C2HC-type containing 1C
chr10_-_81427114 2.110 ENSMUST00000078185.7
ENSMUST00000020461.8
ENSMUST00000105321.3
Nfic


nuclear factor I/C


chr13_+_93674403 2.096 ENSMUST00000048001.6
Dmgdh
dimethylglycine dehydrogenase precursor
chr9_+_43829963 2.080 ENSMUST00000180221.1
Gm3898
predicted gene 3898
chr8_-_121944886 2.070 ENSMUST00000057653.7
Car5a
carbonic anhydrase 5a, mitochondrial
chr4_+_148140699 2.067 ENSMUST00000140049.1
ENSMUST00000105707.1
Mad2l2

MAD2 mitotic arrest deficient-like 2

chr11_-_61378052 2.059 ENSMUST00000010267.3
Slc47a1
solute carrier family 47, member 1
chr19_-_34879452 2.059 ENSMUST00000036584.5
Pank1
pantothenate kinase 1
chr1_+_88200601 2.057 ENSMUST00000049289.8
Ugt1a2
UDP glucuronosyltransferase 1 family, polypeptide A2
chrX_+_142226765 2.042 ENSMUST00000112916.2
Nxt2
nuclear transport factor 2-like export factor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.9 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
2.2 24.1 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
2.1 6.3 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
1.8 5.5 GO:0006713 glucocorticoid catabolic process(GO:0006713)
1.7 18.8 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
1.7 6.6 GO:0042360 vitamin E metabolic process(GO:0042360)
1.6 6.5 GO:0046951 ketone body biosynthetic process(GO:0046951)
1.6 22.5 GO:0015747 urate transport(GO:0015747)
1.6 4.8 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
1.5 4.6 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
1.4 7.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
1.3 44.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
1.3 3.9 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
1.3 3.8 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
1.3 5.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
1.2 3.7 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
1.2 7.3 GO:1905894 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) response to tunicamycin(GO:1904576) cellular response to tunicamycin(GO:1904577) regulation of cellular response to thapsigargin(GO:1905891) negative regulation of cellular response to thapsigargin(GO:1905892) regulation of cellular response to tunicamycin(GO:1905894) negative regulation of cellular response to tunicamycin(GO:1905895)
1.1 4.5 GO:1901373 lipid hydroperoxide transport(GO:1901373)
1.1 3.3 GO:0060523 prostate epithelial cord elongation(GO:0060523)
1.1 3.2 GO:0001172 transcription, RNA-templated(GO:0001172)
1.0 17.0 GO:0060363 cranial suture morphogenesis(GO:0060363)
1.0 3.9 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.0 4.9 GO:0036102 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102)
1.0 8.6 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.9 5.7 GO:0008355 olfactory learning(GO:0008355)
0.9 6.6 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.9 5.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.9 0.9 GO:0002458 peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465)
0.9 3.5 GO:0050787 detoxification of mercury ion(GO:0050787)
0.9 2.6 GO:0034443 negative regulation of lipoprotein oxidation(GO:0034443)
0.9 6.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.8 2.5 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.8 1.7 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.8 4.2 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.8 2.3 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.8 2.3 GO:0019265 glycine biosynthetic process, by transamination of glyoxylate(GO:0019265) L-alanine catabolic process(GO:0042853)
0.7 4.4 GO:0006083 acetate metabolic process(GO:0006083)
0.7 2.8 GO:0098926 postsynaptic signal transduction(GO:0098926) postsynapse to nucleus signaling pathway(GO:0099527)
0.7 2.0 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.7 2.0 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.7 5.3 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.7 2.0 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.6 1.9 GO:0010040 GPI anchor release(GO:0006507) response to iron(II) ion(GO:0010040)
0.6 1.2 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.6 2.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.6 3.7 GO:0015722 canalicular bile acid transport(GO:0015722)
0.6 1.8 GO:1903334 positive regulation of protein folding(GO:1903334)
0.6 2.5 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.6 3.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.6 9.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.6 1.7 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.6 9.1 GO:0052695 cellular glucuronidation(GO:0052695)
0.6 4.0 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.6 1.7 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.6 3.9 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.6 1.7 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.6 2.2 GO:0002780 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
0.5 2.7 GO:0000023 maltose metabolic process(GO:0000023)
0.5 2.7 GO:0060295 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.5 1.6 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.5 1.6 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.5 2.7 GO:0000103 sulfate assimilation(GO:0000103)
0.5 2.1 GO:0090472 dibasic protein processing(GO:0090472)
0.5 4.2 GO:0071494 cellular response to UV-C(GO:0071494)
0.5 2.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.5 2.0 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.5 1.5 GO:0006106 fumarate metabolic process(GO:0006106)
0.5 1.5 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.5 1.5 GO:2000229 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.5 1.5 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.5 1.4 GO:0040010 positive regulation of growth rate(GO:0040010)
0.5 1.9 GO:0006742 NADP catabolic process(GO:0006742)
0.5 2.3 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.5 2.8 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.5 1.4 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.5 1.4 GO:0061144 alveolar secondary septum development(GO:0061144)
0.5 7.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.4 1.3 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.4 11.9 GO:0046688 response to copper ion(GO:0046688)
0.4 3.5 GO:0019695 choline metabolic process(GO:0019695)
0.4 1.3 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.4 1.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.4 2.5 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.4 5.8 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.4 2.5 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.4 1.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.4 1.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.4 3.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.4 1.6 GO:0034759 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.4 1.1 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.4 1.1 GO:0071106 coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.4 1.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.4 1.5 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.4 15.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.4 1.4 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.4 1.4 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.4 7.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.4 0.4 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.4 2.8 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.3 1.4 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.3 4.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.3 5.0 GO:0033866 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.3 4.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 1.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.3 3.2 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.3 1.2 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.3 1.5 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.3 2.4 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.3 2.7 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.3 2.7 GO:0006013 mannose metabolic process(GO:0006013)
0.3 1.5 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.3 1.1 GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.3 2.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.3 1.1 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.3 0.8 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.3 3.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.3 0.8 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.3 3.5 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.3 6.6 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.3 2.1 GO:0060613 fat pad development(GO:0060613)
0.3 1.0 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 4.2 GO:0000338 protein deneddylation(GO:0000338)
0.2 2.0 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.2 2.9 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 1.5 GO:0098707 ferrous iron import across plasma membrane(GO:0098707)
0.2 2.4 GO:0015866 ADP transport(GO:0015866)
0.2 1.7 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.2 1.9 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.2 0.7 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 0.7 GO:0061790 dense core granule docking(GO:0061790)
0.2 1.0 GO:0050975 sensory perception of touch(GO:0050975)
0.2 0.7 GO:0043519 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.2 0.7 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2 0.9 GO:1902044 regulation of Fas signaling pathway(GO:1902044) negative regulation of Fas signaling pathway(GO:1902045)
0.2 3.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 1.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 4.6 GO:0035634 response to stilbenoid(GO:0035634)
0.2 1.1 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.2 0.7 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.2 0.7 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.2 0.7 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.2 0.7 GO:0090264 immune complex clearance by monocytes and macrophages(GO:0002436) monocyte homeostasis(GO:0035702) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265)
0.2 3.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.9 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.2 27.0 GO:0007586 digestion(GO:0007586)
0.2 0.7 GO:0021759 globus pallidus development(GO:0021759)
0.2 1.5 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.2 2.2 GO:0006983 ER overload response(GO:0006983)
0.2 2.0 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.2 1.7 GO:0015865 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.2 1.1 GO:0032782 bile acid secretion(GO:0032782)
0.2 0.6 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.2 3.8 GO:0009404 toxin metabolic process(GO:0009404)
0.2 0.6 GO:0061518 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518)
0.2 0.8 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 1.1 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.2 2.5 GO:0090205 positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.2 1.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.2 0.6 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.2 2.9 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.2 0.8 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.2 0.6 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.2 1.0 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.2 1.5 GO:0097475 motor neuron migration(GO:0097475)
0.2 0.2 GO:2000388 positive regulation of ovarian follicle development(GO:2000386) regulation of antral ovarian follicle growth(GO:2000387) positive regulation of antral ovarian follicle growth(GO:2000388)
0.2 1.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 8.9 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.2 1.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.2 1.7 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 0.6 GO:0060618 nipple development(GO:0060618)
0.2 1.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 3.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.2 1.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.2 3.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 0.5 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.2 1.1 GO:0015862 uridine transport(GO:0015862)
0.2 2.9 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 4.5 GO:0048240 sperm capacitation(GO:0048240)
0.2 0.6 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.2 0.6 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.2 0.6 GO:0071051 snoRNA polyadenylation(GO:0071050) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.2 1.5 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 2.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 1.6 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.7 GO:0061056 sclerotome development(GO:0061056)
0.1 1.0 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 4.1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 0.8 GO:0030242 autophagy of peroxisome(GO:0030242) peroxisome disassembly(GO:1905683)
0.1 0.8 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 1.5 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.7 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.4 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.8 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.7 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.7 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483)
0.1 0.4 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.1 2.1 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.5 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 1.8 GO:0016322 neuron remodeling(GO:0016322)
0.1 1.0 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 3.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.3 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 0.6 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 4.4 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 0.2 GO:0016093 polyprenol metabolic process(GO:0016093)
0.1 0.6 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 3.9 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.2 GO:1902741 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1 1.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.4 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.2 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 1.1 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 0.5 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1 0.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.8 GO:0036444 mitochondrial calcium uptake(GO:0036444)
0.1 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.6 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 7.7 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 0.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 1.0 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 2.4 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.1 0.4 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.5 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 3.9 GO:0006953 acute-phase response(GO:0006953)
0.1 0.9 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.1 1.0 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.4 GO:0042045 epithelial fluid transport(GO:0042045)
0.1 0.2 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 0.9 GO:0046549 retinal cone cell development(GO:0046549)
0.1 3.2 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.1 2.1 GO:0007608 sensory perception of smell(GO:0007608)
0.1 2.8 GO:0071625 vocalization behavior(GO:0071625)
0.1 1.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.6 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 1.1 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.8 GO:1901526 positive regulation of mitophagy in response to mitochondrial depolarization(GO:0098779) positive regulation of mitophagy(GO:1901526)
0.1 1.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 2.1 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.1 1.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 2.0 GO:0007602 phototransduction(GO:0007602)
0.1 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.2 GO:0016240 autophagosome membrane docking(GO:0016240)
0.1 0.7 GO:0046135 pyrimidine ribonucleoside catabolic process(GO:0046133) pyrimidine nucleoside catabolic process(GO:0046135)
0.1 1.1 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.6 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 1.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 1.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.9 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.1 0.9 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.7 GO:0007128 meiotic prophase I(GO:0007128) prophase(GO:0051324)
0.1 1.7 GO:0045187 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 1.6 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 1.8 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 3.6 GO:0031638 zymogen activation(GO:0031638)
0.1 1.1 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 2.0 GO:0032402 melanosome transport(GO:0032402)
0.1 0.8 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.3 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.7 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.2 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 1.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 3.4 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.1 1.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 1.3 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1 0.7 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.1 0.6 GO:0007320 insemination(GO:0007320)
0.1 2.6 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 0.5 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.1 1.0 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.4 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 1.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 0.6 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.8 GO:0043113 receptor clustering(GO:0043113)
0.1 1.5 GO:0022904 respiratory electron transport chain(GO:0022904)
0.1 0.5 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 0.3 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.5 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.1 2.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.7 GO:0006071 glycerol metabolic process(GO:0006071)
0.1 0.2 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.1 4.4 GO:0051591 response to cAMP(GO:0051591)
0.1 0.7 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.1 0.4 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.1 0.6 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.7 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 1.6 GO:0046677 response to antibiotic(GO:0046677)
0.1 1.3 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.1 0.3 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 1.2 GO:0001967 suckling behavior(GO:0001967)
0.1 0.2 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 0.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.1 0.3 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.3 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 0.6 GO:0006826 iron ion transport(GO:0006826)
0.1 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 1.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.4 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 1.1 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1 0.2 GO:0006116 NADH oxidation(GO:0006116)
0.1 0.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.2 GO:0071929 alpha-tubulin acetylation(GO:0071929) positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1 2.9 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 4.5 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.1 1.5 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 0.9 GO:0045475 locomotor rhythm(GO:0045475)
0.1 1.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0042414 epinephrine metabolic process(GO:0042414) response to norepinephrine(GO:0071873)
0.0 0.3 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153) double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.1 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.0 1.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.4 GO:0051255 spindle midzone assembly(GO:0051255)
0.0 1.6 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 2.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 3.7 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 1.4 GO:0097502 mannosylation(GO:0097502)
0.0 0.2 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.0 0.6 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.2 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.7 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.0 0.2 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 1.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 2.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 2.2 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.4 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 3.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.3 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 0.7 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 2.0 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.3 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 1.3 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 0.8 GO:0007635 chemosensory behavior(GO:0007635)
0.0 1.0 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.6 GO:0044550 secondary metabolite biosynthetic process(GO:0044550)
0.0 0.3 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 1.2 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.2 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.0 0.7 GO:0030574 collagen catabolic process(GO:0030574) multicellular organismal catabolic process(GO:0044243)
0.0 0.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.3 GO:0001659 temperature homeostasis(GO:0001659)
0.0 0.1 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.2 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.2 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0001806 type IV hypersensitivity(GO:0001806)
0.0 0.9 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.4 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.5 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 1.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.4 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.7 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 1.0 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.7 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 5.6 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 1.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) activation of protein kinase C activity(GO:1990051)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.4 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.7 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.5 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.4 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.7 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.5 GO:0051923 sulfation(GO:0051923)
0.0 0.8 GO:0019835 cytolysis(GO:0019835)
0.0 1.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.8 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.8 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 1.8 GO:0070988 demethylation(GO:0070988)
0.0 2.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.3 GO:0035089 establishment of apical/basal cell polarity(GO:0035089)
0.0 1.0 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.1 GO:1904427 positive regulation of calcium ion transmembrane transport(GO:1904427)
0.0 0.9 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 1.0 GO:0006094 gluconeogenesis(GO:0006094)
0.0 0.1 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.6 GO:0051341 regulation of oxidoreductase activity(GO:0051341)
0.0 0.1 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.0 GO:0051775 response to redox state(GO:0051775)
0.0 0.9 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.6 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0 0.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758) regulation of macrophage migration(GO:1905521)
0.0 0.2 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.3 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.4 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.8 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.1 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 2.2 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.2 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.0 3.9 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.8 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.3 GO:0030238 male sex determination(GO:0030238)
0.0 0.2 GO:0032328 alanine transport(GO:0032328)
0.0 0.6 GO:1901998 toxin transport(GO:1901998)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.0 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.0 0.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.6 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.6 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.3 GO:0007628 adult walking behavior(GO:0007628)
0.0 0.3 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.5 GO:0008202 steroid metabolic process(GO:0008202)
0.0 0.9 GO:0034341 response to interferon-gamma(GO:0034341)
0.0 0.1 GO:0044062 regulation of excretion(GO:0044062)
0.0 0.0 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.9 GO:0036503 ERAD pathway(GO:0036503)
0.0 0.2 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0033151 V(D)J recombination(GO:0033151)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.0 0.3 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 15.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
1.3 5.4 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
1.3 3.9 GO:0032010 phagolysosome(GO:0032010)
0.7 2.7 GO:1902636 kinociliary basal body(GO:1902636)
0.6 7.3 GO:0097418 neurofibrillary tangle(GO:0097418)
0.5 1.5 GO:0046691 intracellular canaliculus(GO:0046691)
0.5 1.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.5 2.6 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.5 2.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.5 6.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.5 2.8 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.4 1.7 GO:0097447 dendritic tree(GO:0097447)
0.4 1.1 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.4 1.5 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.3 2.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.3 4.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.3 2.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 1.6 GO:0072487 MSL complex(GO:0072487)
0.3 1.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.3 0.9 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.3 0.8 GO:0000814 ESCRT II complex(GO:0000814)
0.3 1.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.3 3.0 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.3 1.9 GO:0005579 membrane attack complex(GO:0005579)
0.3 1.6 GO:0032437 cuticular plate(GO:0032437)
0.3 1.0 GO:0099053 activating signal cointegrator 1 complex(GO:0099053)
0.2 22.5 GO:0070469 respiratory chain(GO:0070469)
0.2 3.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.2 1.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 2.0 GO:0030478 actin cap(GO:0030478)
0.2 31.0 GO:0072562 blood microparticle(GO:0072562)
0.2 1.4 GO:0097452 GAIT complex(GO:0097452)
0.2 0.6 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.2 2.9 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 1.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 1.0 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.2 4.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 1.1 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 0.4 GO:0042611 MHC protein complex(GO:0042611)
0.2 2.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 0.7 GO:0044299 C-fiber(GO:0044299)
0.2 2.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 1.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 2.4 GO:0045179 apical cortex(GO:0045179)
0.2 2.5 GO:0030056 hemidesmosome(GO:0030056)
0.2 0.5 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.2 0.5 GO:0043159 acrosomal matrix(GO:0043159)
0.2 2.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 0.9 GO:0071547 piP-body(GO:0071547)
0.2 3.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 4.2 GO:0033270 paranode region of axon(GO:0033270)
0.2 1.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 1.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 2.1 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 1.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 2.2 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.9 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 2.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 2.0 GO:0031011 Ino80 complex(GO:0031011)
0.1 3.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.0 GO:0005883 neurofilament(GO:0005883)
0.1 2.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 12.5 GO:0005811 lipid droplet(GO:0005811)
0.1 1.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.6 GO:0036501 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) UFD1-NPL4 complex(GO:0036501)
0.1 0.6 GO:1990037 Lewy body core(GO:1990037)
0.1 0.5 GO:0070552 BRISC complex(GO:0070552)
0.1 0.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.6 GO:0005827 polar microtubule(GO:0005827)
0.1 1.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.0 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 3.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 2.8 GO:0045095 keratin filament(GO:0045095)
0.1 3.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.7 GO:0033503 HULC complex(GO:0033503)
0.1 0.3 GO:0097413 Lewy body(GO:0097413)
0.1 1.2 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 0.1 GO:0071920 cleavage body(GO:0071920)
0.1 0.8 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 5.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.5 GO:0036396 MIS complex(GO:0036396)
0.1 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 0.7 GO:0036128 CatSper complex(GO:0036128)
0.1 0.7 GO:0042825 TAP complex(GO:0042825)
0.1 3.2 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.4 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 30.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 1.6 GO:0097386 glial cell projection(GO:0097386)
0.1 0.4 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.3 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 2.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.8 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.0 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 1.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.4 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 2.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 1.0 GO:0071564 npBAF complex(GO:0071564)
0.1 0.6 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 2.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 1.6 GO:0030057 desmosome(GO:0030057)
0.1 0.9 GO:0031045 dense core granule(GO:0031045)
0.1 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.5 GO:0002177 manchette(GO:0002177)
0.0 2.4 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 2.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.5 GO:0000801 central element(GO:0000801)
0.0 2.0 GO:0060076 excitatory synapse(GO:0060076)
0.0 8.5 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 3.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 18.0 GO:0043235 receptor complex(GO:0043235)
0.0 0.4 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.9 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 1.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.3 GO:0071546 pi-body(GO:0071546)
0.0 0.3 GO:0070187 shelterin complex(GO:0070187)
0.0 0.9 GO:0030141 secretory granule(GO:0030141)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 2.4 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 5.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 1.0 GO:0005614 interstitial matrix(GO:0005614)
0.0 3.8 GO:0055037 recycling endosome(GO:0055037)
0.0 57.4 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.0 GO:0044298 cell body membrane(GO:0044298)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 2.1 GO:0000502 proteasome complex(GO:0000502) endopeptidase complex(GO:1905369)
0.0 0.9 GO:0031526 brush border membrane(GO:0031526)
0.0 0.7 GO:0043209 myelin sheath(GO:0043209)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0030663 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 3.4 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.8 GO:0097546 ciliary base(GO:0097546)
0.0 0.4 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 1.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.3 GO:0005770 late endosome(GO:0005770)
0.0 0.2 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.4 GO:0010494 cytoplasmic stress granule(GO:0010494)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 43.2 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
7.2 21.6 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
5.0 14.9 GO:0005186 pheromone activity(GO:0005186)
3.3 13.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
2.8 11.4 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
2.6 10.4 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
2.2 6.6 GO:0008431 vitamin E binding(GO:0008431)
2.1 6.3 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
1.9 5.7 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.8 5.3 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
1.7 10.4 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
1.7 8.6 GO:0008502 melatonin receptor activity(GO:0008502)
1.5 22.5 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
1.5 4.4 GO:0019807 aspartoacylase activity(GO:0019807)
1.4 5.7 GO:0004427 inorganic diphosphatase activity(GO:0004427)
1.1 4.5 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632)
1.1 5.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
1.1 3.2 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
1.1 3.2 GO:0003968 RNA-directed 5'-3' RNA polymerase activity(GO:0003968)
1.0 3.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
1.0 4.8 GO:0032810 sterol response element binding(GO:0032810)
1.0 21.9 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.9 9.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.8 4.9 GO:0051748 UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.8 3.2 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.8 4.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.8 2.4 GO:0016748 succinyltransferase activity(GO:0016748)
0.8 8.6 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.8 5.4 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.7 3.7 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.7 2.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.6 1.9 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.6 1.9 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.6 2.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.6 2.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.6 8.9 GO:0015245 fatty acid transporter activity(GO:0015245)
0.6 8.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.6 21.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.6 2.3 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.5 2.7 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.5 3.8 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.5 1.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.5 1.6 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.5 15.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.5 1.6 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.5 1.6 GO:0031403 lithium ion binding(GO:0031403)
0.5 1.5 GO:0003941 L-serine ammonia-lyase activity(GO:0003941) L-threonine ammonia-lyase activity(GO:0004794)
0.5 2.5 GO:0002054 nucleobase binding(GO:0002054)
0.5 3.0 GO:0005534 galactose binding(GO:0005534)
0.5 6.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.5 3.3 GO:0019238 cyclohydrolase activity(GO:0019238)
0.5 1.4 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.4 3.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.4 1.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.4 3.1 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.4 1.3 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.4 3.8 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.4 2.5 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.4 1.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.4 2.5 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.4 2.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.4 1.6 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.4 1.2 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.4 2.3 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.4 2.0 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.4 2.3 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.4 1.1 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.4 3.0 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.4 1.4 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.4 1.4 GO:0004104 cholinesterase activity(GO:0004104)
0.3 1.7 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.3 1.4 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.3 1.7 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.3 10.2 GO:0005550 pheromone binding(GO:0005550)
0.3 2.6 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.3 7.7 GO:0051787 misfolded protein binding(GO:0051787)
0.3 3.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3 0.9 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.3 1.8 GO:0016215 acyl-CoA desaturase activity(GO:0016215)
0.3 1.4 GO:1990254 keratin filament binding(GO:1990254)
0.3 1.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3 3.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.3 2.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 0.8 GO:0030977 taurine binding(GO:0030977)
0.3 3.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.3 6.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 2.3 GO:0043237 laminin-1 binding(GO:0043237)
0.3 2.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 2.9 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 2.4 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.2 10.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 4.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 4.8 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.2 0.7 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.2 1.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 3.1 GO:0070513 death domain binding(GO:0070513)
0.2 0.7 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.2 2.3 GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity(GO:0004716)
0.2 0.6 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.2 1.5 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 1.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.2 0.8 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 2.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 3.9 GO:0016805 dipeptidase activity(GO:0016805)
0.2 0.6 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.2 66.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 1.2 GO:0005223 intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223)
0.2 1.0 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.2 1.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 1.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 6.7 GO:0016289 CoA hydrolase activity(GO:0016289)
0.2 1.5 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2 2.7 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.2 0.8 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 1.5 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.2 3.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 2.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 1.9 GO:0004630 phospholipase D activity(GO:0004630)
0.2 3.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 1.4 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.2 0.9 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 1.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 0.7 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.2 0.7 GO:0008169 C-methyltransferase activity(GO:0008169)
0.2 0.7 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 2.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 1.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 0.6 GO:0031699 beta-3 adrenergic receptor binding(GO:0031699)
0.2 3.0 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 0.6 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding(GO:0036435)
0.2 0.5 GO:0030350 iron-responsive element binding(GO:0030350)
0.2 2.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 2.7 GO:0050692 DBD domain binding(GO:0050692)
0.2 0.6 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 1.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.7 GO:0055100 adiponectin binding(GO:0055100)
0.1 0.9 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.9 GO:0036458 hepatocyte growth factor binding(GO:0036458)
0.1 3.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 1.7 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.7 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.9 GO:0032052 bile acid binding(GO:0032052)
0.1 2.8 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 0.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.0 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 2.0 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.4 GO:0071820 N-box binding(GO:0071820)
0.1 2.0 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 1.1 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 2.3 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.1 1.5 GO:0015250 water channel activity(GO:0015250)
0.1 0.5 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.5 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 2.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.9 GO:0017166 vinculin binding(GO:0017166)
0.1 1.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 3.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 1.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.9 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 4.1 GO:0005549 odorant binding(GO:0005549)
0.1 0.3 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.1 1.0 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.7 GO:0050897 cobalt ion binding(GO:0050897)
0.1 2.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 1.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 2.6 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 0.4 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 1.0 GO:0042301 phosphate ion binding(GO:0042301)
0.1 0.3 GO:0046870 cadmium ion binding(GO:0046870)
0.1 0.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.1 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.1 3.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.2 GO:0032190 acrosin binding(GO:0032190)
0.1 2.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.7 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.1 0.8 GO:0015266 protein channel activity(GO:0015266)
0.1 1.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.5 GO:0034604 dihydrolipoyl dehydrogenase activity(GO:0004148) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) dihydrolipoyllysine-residue acetyltransferase activity(GO:0004742) S-acetyltransferase activity(GO:0016418) dihydrolipoamide S-acyltransferase activity(GO:0030523) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.7 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.4 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 1.1 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.7 GO:0008276 protein methyltransferase activity(GO:0008276)
0.1 0.6 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.9 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.7 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 2.1 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.5 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 0.6 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.5 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.3 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 0.6 GO:0071253 connexin binding(GO:0071253)
0.1 0.2 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.4 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.3 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 2.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 1.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 2.0 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.6 GO:0022829 wide pore channel activity(GO:0022829)
0.1 3.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.6 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.1 4.0 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 2.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.4 GO:0005537 mannose binding(GO:0005537)
0.1 0.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 2.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 0.2 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.1 0.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.5 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 1.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.3 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 1.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 4.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.9 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 1.3 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.1 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.9 GO:0005123 death receptor binding(GO:0005123)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 1.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 5.9 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 2.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.2 GO:0031489 myosin V binding(GO:0031489)
0.0 1.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 1.0 GO:0008483 transaminase activity(GO:0008483)
0.0 0.9 GO:0008009 chemokine activity(GO:0008009)
0.0 1.0 GO:0005542 folic acid binding(GO:0005542)
0.0 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0019969 interleukin-10 receptor activity(GO:0004920) interleukin-10 binding(GO:0019969)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.6 GO:0003796 lysozyme activity(GO:0003796)
0.0 2.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 1.0 GO:0097718 disordered domain specific binding(GO:0097718)
0.0 0.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 2.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.7 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 1.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.7 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 1.6 GO:0005507 copper ion binding(GO:0005507)
0.0 0.2 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 1.0 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.3 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.6 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 1.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.0 1.3 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.8 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 2.1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 1.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 2.9 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0004825 methionine-tRNA ligase activity(GO:0004825)
0.0 0.8 GO:0017171 serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0 1.3 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.8 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.2 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.9 GO:0045182 translation regulator activity(GO:0045182)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.0 3.3 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.4 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.5 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006) epidermal growth factor binding(GO:0048408)
0.0 0.0 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.4 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.6 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 3.1 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 1.4 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.0 0.8 GO:0008565 protein transporter activity(GO:0008565)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 12.3 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 7.7 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 2.3 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 6.0 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 10.8 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 4.8 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.7 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 6.4 PID_FOXO_PATHWAY FoxO family signaling
0.1 0.8 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.1 4.2 PID_ARF6_PATHWAY Arf6 signaling events
0.1 5.2 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 2.6 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 1.3 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.1 3.4 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.3 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.1 0.7 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 1.6 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.1 3.1 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 4.6 PID_FGF_PATHWAY FGF signaling pathway
0.1 2.3 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.8 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.1 2.0 PID_ARF_3PATHWAY Arf1 pathway
0.1 1.3 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 3.3 PID_BMP_PATHWAY BMP receptor signaling
0.1 1.5 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.1 0.8 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.1 1.3 PID_IFNG_PATHWAY IFN-gamma pathway
0.1 1.5 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.1 1.5 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 0.6 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 2.0 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.4 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.6 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.6 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.0 1.0 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 2.3 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 1.3 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.6 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.5 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 1.3 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.4 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.3 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.5 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.2 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 1.2 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 0.4 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 0.2 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.3 PID_AP1_PATHWAY AP-1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 26.5 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
1.3 11.5 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.7 2.1 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.6 7.7 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.5 5.8 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.5 1.6 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.5 4.5 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.4 4.1 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.4 13.0 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.4 5.7 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.4 2.0 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.4 6.0 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.4 3.0 REACTOME_OPSINS Genes involved in Opsins
0.3 4.1 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.3 0.9 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 4.0 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.3 10.7 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.3 3.0 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 4.1 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.2 13.9 REACTOME_PHASE_II_CONJUGATION Genes involved in Phase II conjugation
0.2 0.7 REACTOME_INFLUENZA_LIFE_CYCLE Genes involved in Influenza Life Cycle
0.2 4.6 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 2.2 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 4.9 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 3.3 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 3.3 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 9.1 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 1.5 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.2 REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 1.8 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 3.2 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 0.7 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 2.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.3 REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.1 1.4 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 4.0 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 2.4 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 2.8 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.7 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.8 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 9.1 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 3.0 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 3.3 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 2.0 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.1 8.0 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 3.8 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 0.6 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.1 4.3 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 3.0 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.1 2.3 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.1 1.5 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 1.4 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.2 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.6 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 1.4 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 0.9 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 2.2 REACTOME_FGFR_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR ligand binding and activation
0.1 2.3 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 1.1 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.1 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.9 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 0.7 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.1 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.7 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.2 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.8 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 0.9 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.1 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.5 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 1.3 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 2.5 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 4.8 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 2.1 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.0 0.4 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.5 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.4 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.8 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.9 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.4 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.8 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.0 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.8 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.7 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.3 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 1.5 REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.5 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.7 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.0 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.0 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.7 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 1.2 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis