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GSE58827: Dynamics of the Mouse Liver

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Results for Hoxd1

Z-value: 0.49

Motif logo

Transcription factors associated with Hoxd1

Gene Symbol Gene ID Gene Info
ENSMUSG00000042448.4 homeobox D1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxd1mm10_v2_chr2_+_74762980_747629800.077.0e-01Click!

Activity profile of Hoxd1 motif

Sorted Z-values of Hoxd1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_7966000 2.05 ENSMUST00000182102.1
ENSMUST00000075619.4
solute carrier family 22, member 27
chr2_-_164638789 1.25 ENSMUST00000109336.1
WAP four-disulfide core domain 16
chr7_-_48843663 1.23 ENSMUST00000167786.2
cysteine and glycine-rich protein 3
chr7_-_140154712 1.19 ENSMUST00000059241.7
shadow of prion protein
chr9_-_15301555 1.12 ENSMUST00000034414.8
RIKEN cDNA 4931406C07 gene
chr3_-_113291449 1.07 ENSMUST00000179568.1
amylase 2a4
chr17_-_45659312 1.06 ENSMUST00000120717.1
calpain 11
chr1_+_88070765 1.03 ENSMUST00000073772.4
UDP glucuronosyltransferase 1 family, polypeptide A9
chr10_+_63024315 1.01 ENSMUST00000124784.1
phenazine biosynthesis-like protein domain containing 2
chrX_-_75843185 0.97 ENSMUST00000137192.1
plastin 3 (T-isoform)
chr2_+_109917639 0.93 ENSMUST00000046548.7
ENSMUST00000111037.2
leucine-rich repeat-containing G protein-coupled receptor 4
chr2_+_69897255 0.90 ENSMUST00000131553.1
ubiquitin protein ligase E3 component n-recognin 3
chrX_-_75843063 0.86 ENSMUST00000114057.1
plastin 3 (T-isoform)
chr4_+_102570065 0.85 ENSMUST00000097950.2
phosphodiesterase 4B, cAMP specific
chr9_-_107872403 0.83 ENSMUST00000183035.1
RNA binding motif protein 6
chr17_-_36032682 0.82 ENSMUST00000102678.4
histocompatibility 2, T region locus 23
chr19_+_58759700 0.82 ENSMUST00000026081.3
pancreatic lipase-related protein 2
chr1_+_88055467 0.76 ENSMUST00000173325.1
UDP glycosyltransferase 1 family, polypeptide A10
chrM_+_9870 0.73 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr12_-_98577940 0.73 ENSMUST00000110113.1
potassium channel, subfamily K, member 10
chr18_-_60273267 0.73 ENSMUST00000090260.4
predicted gene 4841
chr1_+_88055377 0.72 ENSMUST00000138182.1
ENSMUST00000113142.3
UDP glycosyltransferase 1 family, polypeptide A10
chr2_+_116067213 0.71 ENSMUST00000152412.1
RIKEN cDNA G630016G05 gene
chr5_-_62766153 0.68 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr9_+_66797039 0.67 ENSMUST00000098612.2
predicted gene 10647
chr2_-_155074447 0.67 ENSMUST00000137242.1
ENSMUST00000054607.9
S-adenosylhomocysteine hydrolase
chr1_-_65186456 0.66 ENSMUST00000169032.1
isocitrate dehydrogenase 1 (NADP+), soluble
chr2_+_69897220 0.66 ENSMUST00000055758.9
ENSMUST00000112251.2
ubiquitin protein ligase E3 component n-recognin 3
chr2_-_20943413 0.65 ENSMUST00000140230.1
Rho GTPase activating protein 21
chr1_-_24612700 0.64 ENSMUST00000088336.1
predicted gene 10222
chr18_-_3281036 0.61 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
cAMP responsive element modulator
chr17_-_28560704 0.59 ENSMUST00000114785.1
ENSMUST00000025062.3
colipase, pancreatic
chr19_+_3323301 0.58 ENSMUST00000025835.4
carnitine palmitoyltransferase 1a, liver
chr6_-_130193112 0.58 ENSMUST00000112032.1
ENSMUST00000071554.2
killer cell lectin-like receptor subfamily A, member 9
chr2_-_156392829 0.58 ENSMUST00000088578.2
RIKEN cDNA 2900097C17 gene
chr3_+_19985612 0.58 ENSMUST00000172860.1
ceruloplasmin
chr5_+_90561102 0.58 ENSMUST00000094615.4
RIKEN cDNA 5830473C10 gene
chr6_+_149582012 0.57 ENSMUST00000144085.2
predicted gene, 21814
chrM_+_10167 0.54 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr5_-_77115145 0.53 ENSMUST00000081964.5
HOP homeobox
chr6_-_83656082 0.53 ENSMUST00000014686.2
C-type lectin domain family 4, member f
chr15_+_98571004 0.53 ENSMUST00000023728.6
RIKEN cDNA 4930415O20 gene
chr2_+_126556128 0.50 ENSMUST00000141482.2
solute carrier family 27 (fatty acid transporter), member 2
chr7_+_79273201 0.48 ENSMUST00000037315.6
abhydrolase domain containing 2
chr9_-_45204083 0.48 ENSMUST00000034599.8
transmembrane protease, serine 4
chr6_-_130026954 0.46 ENSMUST00000074056.2
killer cell lectin-like receptor, subfamily A, member 6
chr5_-_87490869 0.46 ENSMUST00000147854.1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr1_-_4360256 0.45 ENSMUST00000027032.4
retinitis pigmentosa 1 (human)
chrX_-_143933089 0.44 ENSMUST00000087313.3
doublecortin
chr9_+_72958785 0.44 ENSMUST00000098567.2
ENSMUST00000034734.8
dyslexia susceptibility 1 candidate 1 homolog (human)
chr15_+_25773985 0.43 ENSMUST00000125667.1
myosin X
chr8_-_41041828 0.43 ENSMUST00000051379.7
mitochondrial tumor suppressor 1
chr5_-_123012874 0.43 ENSMUST00000172729.1
lysine (K)-specific demethylase 2B
chr9_-_123851855 0.43 ENSMUST00000184082.1
ENSMUST00000167595.2
FYVE and coiled-coil domain containing 1
chrX_+_107255878 0.43 ENSMUST00000101294.2
ENSMUST00000118820.1
ENSMUST00000120971.1
G protein-coupled receptor 174
chr6_-_57535422 0.43 ENSMUST00000042766.3
protein phosphatase 1K (PP2C domain containing)
chr3_-_116712644 0.42 ENSMUST00000029569.2
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr5_+_29195983 0.41 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
ring finger protein 32
chr6_-_130129898 0.41 ENSMUST00000014476.5
killer cell lectin-like receptor, subfamily A, member 8
chr5_-_63968867 0.41 ENSMUST00000154169.1
RELT-like 1
chr11_-_121388186 0.40 ENSMUST00000106107.2
Rab40b, member RAS oncogene family
chr11_+_109543694 0.39 ENSMUST00000106696.1
arylsulfatase G
chr2_+_121956651 0.39 ENSMUST00000110574.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr9_-_85749308 0.39 ENSMUST00000039213.8
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr13_-_67332525 0.38 ENSMUST00000168892.1
ENSMUST00000109735.2
zinc finger protein 595
chr4_+_147492417 0.38 ENSMUST00000105721.2
predicted gene 13152
chr2_-_69712461 0.37 ENSMUST00000102706.3
ENSMUST00000073152.6
FAST kinase domains 1
chr14_+_55559993 0.37 ENSMUST00000117236.1
DDB1 and CUL4 associated factor 11
chr3_-_85722474 0.37 ENSMUST00000119077.1
family with sequence similarity 160, member A1
chr5_-_108795352 0.37 ENSMUST00000004943.1
transmembrane emp24 protein transport domain containing
chr9_+_119341487 0.36 ENSMUST00000175743.1
ENSMUST00000176397.1
acetyl-Coenzyme A acyltransferase 1A
chr16_+_11406618 0.36 ENSMUST00000122168.1
sorting nexin 29
chr6_+_78370877 0.36 ENSMUST00000096904.3
regenerating islet-derived 3 beta
chr7_+_29816061 0.35 ENSMUST00000032796.6
ENSMUST00000178162.1
zinc finger protein 790
chr16_-_16600533 0.35 ENSMUST00000159542.1
FYVE, RhoGEF and PH domain containing 4
chr9_+_119341294 0.35 ENSMUST00000039784.5
acetyl-Coenzyme A acyltransferase 1A
chr8_+_46010596 0.34 ENSMUST00000110381.2
Lrp2 binding protein
chr2_-_160619971 0.34 ENSMUST00000109473.1
predicted gene 14221
chr3_-_16006332 0.33 ENSMUST00000108347.2
predicted gene 5150
chr15_-_101892916 0.33 ENSMUST00000100179.1
keratin 76
chr17_+_88440711 0.33 ENSMUST00000112238.2
ENSMUST00000155640.1
forkhead box N2
chr2_+_121956411 0.33 ENSMUST00000110578.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr12_+_10390756 0.33 ENSMUST00000020947.5
retinol dehydrogenase 14 (all-trans and 9-cis)
chr15_-_8710734 0.32 ENSMUST00000005493.7
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr18_+_12741324 0.31 ENSMUST00000115857.2
ENSMUST00000121018.1
ENSMUST00000119108.1
calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)
chr14_+_47298260 0.31 ENSMUST00000166743.1
mitogen-activated protein kinase 1 interacting protein 1-like
chr2_+_91257323 0.31 ENSMUST00000111349.2
ENSMUST00000131711.1
protein kinase C and casein kinase substrate in neurons 3
chr17_-_40242285 0.31 ENSMUST00000026499.5
cysteine-rich secretory protein 3
chr9_-_55919605 0.31 ENSMUST00000037408.8
S phase cyclin A-associated protein in the ER
chr3_-_15426427 0.31 ENSMUST00000099201.3
signal-regulatory protein beta 1A
chr2_+_32606946 0.30 ENSMUST00000113290.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chrX_-_60893430 0.30 ENSMUST00000135107.2
SRY-box containing gene 3
chr19_-_37330613 0.30 ENSMUST00000131070.1
insulin degrading enzyme
chr19_-_39649046 0.30 ENSMUST00000067328.6
cytochrome P450, family 2, subfamily c, polypeptide 67
chrX_-_99470672 0.30 ENSMUST00000113797.3
ENSMUST00000113790.1
ENSMUST00000036354.6
ENSMUST00000167246.1
praja1, RING-H2 motif containing
chr6_-_69284319 0.29 ENSMUST00000103349.1
immunoglobulin kappa variable 4-69
chr2_-_177267036 0.29 ENSMUST00000108963.1
predicted gene 14409
chr2_-_116067391 0.28 ENSMUST00000140185.1
RIKEN cDNA 2700033N17 gene
chr2_+_32606979 0.28 ENSMUST00000113289.1
ENSMUST00000095044.3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr10_-_8886033 0.28 ENSMUST00000015449.5
SAM and SH3 domain containing 1
chr6_+_68161415 0.28 ENSMUST00000168090.1
immunoglobulin kappa variable 1-115
chr13_-_102905740 0.27 ENSMUST00000167462.1
microtubule associated serine/threonine kinase family member 4
chr5_+_102768771 0.26 ENSMUST00000112852.1
Rho GTPase activating protein 24
chr1_-_33814516 0.26 ENSMUST00000044455.5
ENSMUST00000115167.1
zinc finger protein 451
chr10_+_94575257 0.25 ENSMUST00000121471.1
transmembrane and coiled coil domains 3
chr13_+_42866247 0.25 ENSMUST00000131942.1
phosphatase and actin regulator 1
chr4_+_95557494 0.25 ENSMUST00000079223.4
ENSMUST00000177394.1
FGGY carbohydrate kinase domain containing
chr6_-_116716888 0.24 ENSMUST00000056623.6
transmembrane protein 72
chr2_+_3424123 0.24 ENSMUST00000061852.5
ENSMUST00000100463.3
ENSMUST00000102988.3
ENSMUST00000115066.1
DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)
chr1_-_33814591 0.23 ENSMUST00000019861.6
zinc finger protein 451
chr6_-_69400097 0.23 ENSMUST00000177795.1
immunoglobulin kappa variable 4-62
chr1_+_65186727 0.23 ENSMUST00000097707.4
ENSMUST00000081154.7
phosphoinositide kinase, FYVE finger containing
chr12_-_112802646 0.23 ENSMUST00000124526.1
AHNAK nucleoprotein 2
chr6_-_124779686 0.22 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
leucine rich repeat containing 23
chr3_-_15848419 0.22 ENSMUST00000108354.1
ENSMUST00000108349.1
ENSMUST00000108352.2
ENSMUST00000108350.1
ENSMUST00000050623.4
signal-regulatory protein beta 1C
chr11_-_107337556 0.21 ENSMUST00000040380.6
phosphatidylinositol transfer protein, cytoplasmic 1
chrX_+_16619698 0.21 ENSMUST00000026013.5
monoamine oxidase A
chr12_+_80644212 0.20 ENSMUST00000085245.5
solute carrier family 39 (zinc transporter), member 9
chr8_+_113635787 0.20 ENSMUST00000035777.8
MON1 homolog b (yeast)
chr10_-_86011833 0.20 ENSMUST00000105304.1
ENSMUST00000061699.5
BPI fold containing family C
chr10_-_92375367 0.19 ENSMUST00000182870.1
predicted gene, 20757
chr2_-_150255591 0.19 ENSMUST00000063463.5
predicted gene 21994
chr7_+_30977043 0.19 ENSMUST00000058093.4
family with sequence similarity 187, member B
chr3_-_41742471 0.19 ENSMUST00000026866.8
sodium channel and clathrin linker 1
chr5_+_107497762 0.19 ENSMUST00000152474.1
ENSMUST00000060553.7
RIKEN cDNA A830010M20 gene
chr13_+_24802020 0.19 ENSMUST00000155575.1
cDNA sequence BC005537
chrX_-_160138375 0.18 ENSMUST00000033662.8
pyruvate dehydrogenase E1 alpha 1
chr11_-_99374895 0.18 ENSMUST00000006963.2
keratin 28
chr13_-_102906046 0.17 ENSMUST00000171791.1
microtubule associated serine/threonine kinase family member 4
chr14_+_48446128 0.17 ENSMUST00000124720.1
transmembrane protein 260
chr4_+_103143052 0.17 ENSMUST00000106855.1
mesoderm induction early response 1 homolog (Xenopus laevis
chr8_+_113635550 0.16 ENSMUST00000179926.1
MON1 homolog b (yeast)
chr6_+_115931922 0.16 ENSMUST00000032471.6
rhodopsin
chr3_-_96452306 0.16 ENSMUST00000093126.4
ENSMUST00000098841.3
cDNA sequence BC107364
chr1_+_157506777 0.16 ENSMUST00000027881.8
SEC16 homolog B (S. cerevisiae)
chr4_-_148152059 0.16 ENSMUST00000056965.5
ENSMUST00000168503.1
ENSMUST00000152098.1
F-box protein 6
chrX_+_160768013 0.16 ENSMUST00000033650.7
retinoschisis (X-linked, juvenile) 1 (human)
chr1_+_157506728 0.16 ENSMUST00000086130.2
SEC16 homolog B (S. cerevisiae)
chr14_+_69347587 0.16 ENSMUST00000064831.5
ectonucleoside triphosphate diphosphohydrolase 4
chr14_-_51071442 0.16 ENSMUST00000048478.5
olfactory receptor 750
chr5_-_90640464 0.15 ENSMUST00000031317.6
Ras association (RalGDS/AF-6) domain family member 6
chr14_+_122034660 0.15 ENSMUST00000045976.6
translocase of inner mitochondrial membrane 8A2
chr11_+_99873389 0.15 ENSMUST00000093936.3
keratin associated protein 9-1
chrX_-_143933204 0.14 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
doublecortin
chr7_+_135268579 0.14 ENSMUST00000097983.3
neuropeptide S
chr18_+_31609512 0.14 ENSMUST00000164667.1
RIKEN cDNA B930094E09 gene
chr10_+_57650990 0.14 ENSMUST00000175852.1
protein kinase inhibitor beta, cAMP dependent, testis specific
chr19_-_41933276 0.14 ENSMUST00000075280.4
ENSMUST00000112123.2
exosome component 1
chr15_-_37459327 0.14 ENSMUST00000119730.1
ENSMUST00000120746.1
neurocalcin delta
chr6_+_116650674 0.14 ENSMUST00000067354.5
ENSMUST00000178241.1
RIKEN cDNA 8430408G22 gene
chr7_-_24724237 0.13 ENSMUST00000081657.4
predicted gene 4763
chr13_+_24801657 0.13 ENSMUST00000019276.4
cDNA sequence BC005537
chr2_+_170731807 0.13 ENSMUST00000029075.4
docking protein 5
chr13_-_74807913 0.12 ENSMUST00000065629.4
calpastatin
chr5_+_145204523 0.12 ENSMUST00000085671.3
ENSMUST00000031601.7
zinc finger with KRAB and SCAN domains 5
chr2_+_37516618 0.12 ENSMUST00000065441.6
G protein-coupled receptor 21
chr16_+_18836573 0.12 ENSMUST00000055413.6
RIKEN cDNA 2510002D24 gene
chr4_+_145514884 0.12 ENSMUST00000105741.1
predicted gene 13225
chr17_-_32822200 0.12 ENSMUST00000179695.1
zinc finger protein 799
chr10_-_112928974 0.11 ENSMUST00000099276.2
ataxin 7-like 3B
chr7_+_130774069 0.11 ENSMUST00000048453.5
BTB (POZ) domain containing 16
chr11_-_100088226 0.11 ENSMUST00000107419.1
keratin 32
chr3_+_94837702 0.10 ENSMUST00000107266.1
ENSMUST00000042402.5
ENSMUST00000107269.1
pogo transposable element with ZNF domain
chr15_+_38661904 0.10 ENSMUST00000022904.6
ATPase, H+ transporting, lysosomal V1 subunit C1
chr15_-_8710409 0.10 ENSMUST00000157065.1
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr17_-_32886083 0.10 ENSMUST00000178401.1
zinc finger protein 870
chr11_-_99244058 0.10 ENSMUST00000103132.3
ENSMUST00000038214.6
keratin 222
chr12_-_84617326 0.10 ENSMUST00000021666.4
ATP-binding cassette, sub-family D (ALD), member 4
chr2_-_132247747 0.09 ENSMUST00000110163.1
ENSMUST00000180286.1
ENSMUST00000028816.2
transmembrane protein 230
chr11_-_30649510 0.09 ENSMUST00000074613.3
acylphosphatase 2, muscle type
chr18_+_37355271 0.09 ENSMUST00000051163.1
protocadherin beta 8
chr17_-_36462329 0.09 ENSMUST00000169950.1
ENSMUST00000057502.7
histocompatibility 2, M region locus 10.4
chr5_-_3647806 0.09 ENSMUST00000119783.1
ENSMUST00000007559.8
GATA zinc finger domain containing 1
chr15_+_82256023 0.09 ENSMUST00000143238.1
RIKEN cDNA 1500009C09 gene
chr19_+_23723279 0.09 ENSMUST00000067077.1
predicted gene 9938
chr8_-_122915987 0.09 ENSMUST00000098333.4
ankyrin repeat domain 11
chr19_-_53944621 0.08 ENSMUST00000135402.2
BBSome interacting protein 1
chr4_+_146514920 0.08 ENSMUST00000140089.1
ENSMUST00000179175.1
predicted gene 13247
chr9_-_105395237 0.08 ENSMUST00000140851.1
NIMA (never in mitosis gene a)-related expressed kinase 11
chr7_+_18245347 0.08 ENSMUST00000066780.4
MHC I like leukocyte 1
chr16_+_45224315 0.08 ENSMUST00000102802.3
ENSMUST00000063654.4
B and T lymphocyte associated
chr7_+_127511976 0.08 ENSMUST00000098025.4
Snf2-related CREBBP activator protein
chr19_-_32196393 0.08 ENSMUST00000151822.1
sphingomyelin synthase 1
chr1_-_185329331 0.08 ENSMUST00000027921.4
ENSMUST00000110975.1
ENSMUST00000110974.3
isoleucine-tRNA synthetase 2, mitochondrial
chr9_-_86880647 0.08 ENSMUST00000167014.1
synaptosomal-associated protein 91
chr6_-_3399545 0.07 ENSMUST00000120087.3
sterile alpha motif domain containing 9-like
chr2_-_84715160 0.07 ENSMUST00000035840.5
zinc finger, DHHC domain containing 5
chr2_-_45117349 0.07 ENSMUST00000176438.2
zinc finger E-box binding homeobox 2
chr16_+_88728828 0.06 ENSMUST00000060494.6
keratin associated protein 13-1
chr11_-_4095344 0.06 ENSMUST00000004868.5
mitochondrial fission process 1
chr17_+_34931253 0.06 ENSMUST00000007253.5
neuraminidase 1
chr9_-_70934808 0.06 ENSMUST00000034731.8
lipase, hepatic
chr1_+_88306731 0.06 ENSMUST00000040210.7
transient receptor potential cation channel, subfamily M, member 8
chr13_-_105054895 0.06 ENSMUST00000063551.5
regulator of G-protein signalling 7 binding protein
chr9_+_105395348 0.06 ENSMUST00000035181.3
asteroid homolog 1 (Drosophila)
chr1_-_158356258 0.06 ENSMUST00000004133.8
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr19_-_39886730 0.05 ENSMUST00000168838.1
cytochrome P450, family 2, subfamily c, polypeptide 69
chr4_-_14621669 0.05 ENSMUST00000143105.1
solute carrier family 26, member 7
chr10_+_57650977 0.05 ENSMUST00000066028.6
protein kinase inhibitor beta, cAMP dependent, testis specific
chr11_-_115419917 0.05 ENSMUST00000106537.1
ENSMUST00000043931.2
ENSMUST00000073791.3
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxd1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1903918 regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919)
0.4 1.6 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.3 0.9 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.2 0.7 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 2.5 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 0.8 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.2 0.5 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.2 0.7 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.2 0.5 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.1 2.1 GO:0015747 urate transport(GO:0015747)
0.1 0.6 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.4 GO:0019085 early viral transcription(GO:0019085)
0.1 0.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.3 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.4 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.4 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 1.8 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.5 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 0.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.9 GO:0019377 glycolipid catabolic process(GO:0019377)
0.0 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.5 GO:0051132 NK T cell activation(GO:0051132)
0.0 0.4 GO:1903208 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.0 0.2 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.6 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.4 GO:0030035 microspike assembly(GO:0030035)
0.0 0.5 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.0 0.3 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.3 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.5 GO:0032570 response to progesterone(GO:0032570)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.3 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.7 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 0.2 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.6 GO:0046688 response to copper ion(GO:0046688)
0.0 0.2 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.6 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.7 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.7 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.6 GO:0032094 response to food(GO:0032094)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.0 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.0 0.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.1 GO:0021767 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.8 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.2 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.5 GO:0097542 ciliary tip(GO:0097542)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.1 GO:0098830 presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 1.6 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.6 GO:0070469 respiratory chain(GO:0070469)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.2 1.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 1.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 2.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.7 GO:0008410 acetyl-CoA C-acetyltransferase activity(GO:0003985) CoA-transferase activity(GO:0008410) palmitoyl-CoA oxidase activity(GO:0016401) C-acetyltransferase activity(GO:0016453)
0.1 0.6 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.7 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 3.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.4 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.5 GO:0005534 galactose binding(GO:0005534)
0.1 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.8 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.9 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.3 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.1 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.4 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.3 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 0.4 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0052796 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.5 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 0.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.6 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport