Motif ID: Hoxd11_Cdx1_Hoxc11

Z-value: 1.400

Transcription factors associated with Hoxd11_Cdx1_Hoxc11:

Gene SymbolEntrez IDGene Name
Cdx1 ENSMUSG00000024619.8 Cdx1
Hoxc11 ENSMUSG00000001656.3 Hoxc11
Hoxd11 ENSMUSG00000042499.12 Hoxd11

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hoxc11mm10_v2_chr15_+_102954427_1029544270.564.1e-04Click!
Hoxd11mm10_v2_chr2_+_74681991_746820070.511.6e-03Click!
Cdx1mm10_v2_chr18_-_61036189_610362100.353.7e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd11_Cdx1_Hoxc11

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_142661858 26.035 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr2_+_84988194 14.260 ENSMUST00000028466.5
Prg3
proteoglycan 3
chr14_-_37110087 9.220 ENSMUST00000179488.1
2610528A11Rik
RIKEN cDNA 2610528A11 gene
chrX_+_96455359 8.470 ENSMUST00000033553.7
Heph
hephaestin
chr1_+_107535508 7.944 ENSMUST00000182198.1
Serpinb10
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
chr19_-_45812291 6.768 ENSMUST00000086993.4
Kcnip2
Kv channel-interacting protein 2
chr17_+_5799491 6.440 ENSMUST00000181484.1
3300005D01Rik
RIKEN cDNA 3300005D01 gene
chr1_-_45503282 6.338 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr2_+_155611175 5.904 ENSMUST00000092995.5
Myh7b
myosin, heavy chain 7B, cardiac muscle, beta
chr9_+_62858085 5.638 ENSMUST00000034777.6
ENSMUST00000163820.1
Calml4

calmodulin-like 4

chrX_+_106920618 5.321 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr1_-_89933290 5.319 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr10_+_119992916 5.253 ENSMUST00000105261.2
Grip1
glutamate receptor interacting protein 1
chr10_+_45577811 5.171 ENSMUST00000037044.6
Hace1
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
chr17_-_43502773 5.091 ENSMUST00000024707.8
ENSMUST00000117137.1
Mep1a

meprin 1 alpha

chr17_+_71019548 5.067 ENSMUST00000073211.5
ENSMUST00000179759.1
Myom1

myomesin 1

chr9_+_65890237 4.717 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr17_+_71019503 4.698 ENSMUST00000024847.7
Myom1
myomesin 1
chr4_-_133968611 4.435 ENSMUST00000102552.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr3_-_123034943 4.431 ENSMUST00000029761.7
Myoz2
myozenin 2
chr15_+_81936753 4.380 ENSMUST00000038757.7
Csdc2
cold shock domain containing C2, RNA binding
chr15_-_78855517 4.379 ENSMUST00000044584.4
Lgals2
lectin, galactose-binding, soluble 2
chr5_-_73191848 4.351 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr19_+_53529100 4.310 ENSMUST00000038287.6
Dusp5
dual specificity phosphatase 5
chr4_+_11758147 4.216 ENSMUST00000029871.5
ENSMUST00000108303.1
Cdh17

cadherin 17

chr14_+_74640840 4.087 ENSMUST00000036653.3
Htr2a
5-hydroxytryptamine (serotonin) receptor 2A
chr1_-_163289214 4.084 ENSMUST00000183691.1
Prrx1
paired related homeobox 1
chrX_+_164140447 4.073 ENSMUST00000073973.4
Ace2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr4_-_154636831 3.973 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr11_-_99244058 3.932 ENSMUST00000103132.3
ENSMUST00000038214.6
Krt222

keratin 222

chr1_+_63176818 3.915 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr7_-_134232005 3.891 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr15_+_81936911 3.846 ENSMUST00000135663.1
Csdc2
cold shock domain containing C2, RNA binding
chr13_-_84064772 3.748 ENSMUST00000182477.1
Gm17750
predicted gene, 17750
chr6_-_52226165 3.617 ENSMUST00000114425.2
Hoxa9
homeobox A9
chr17_+_5799616 3.600 ENSMUST00000181392.1
3300005D01Rik
RIKEN cDNA 3300005D01 gene
chr7_-_134232125 3.450 ENSMUST00000127524.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr6_-_139501907 3.413 ENSMUST00000170650.1
Rergl
RERG/RAS-like
chr5_-_73256555 3.334 ENSMUST00000101127.5
ENSMUST00000171179.1
Fryl
Fryl
furry homolog-like (Drosophila)
furry homolog-like (Drosophila)
chr19_-_7341792 3.207 ENSMUST00000164205.1
ENSMUST00000165286.1
ENSMUST00000168324.1
ENSMUST00000032557.8
Mark2



MAP/microtubule affinity-regulating kinase 2



chr8_+_69902178 3.186 ENSMUST00000050373.5
Tssk6
testis-specific serine kinase 6
chr4_-_133967296 3.147 ENSMUST00000105893.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr3_-_144760841 3.134 ENSMUST00000059091.5
Clca1
chloride channel calcium activated 1
chr14_+_65805832 3.075 ENSMUST00000022612.3
Pbk
PDZ binding kinase
chr2_-_32387760 3.067 ENSMUST00000050785.8
Lcn2
lipocalin 2
chr8_+_57332111 3.066 ENSMUST00000181638.1
5033428I22Rik
RIKEN cDNA 5033428I22 gene
chr14_+_65806066 3.048 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr9_-_39604124 3.014 ENSMUST00000042485.4
ENSMUST00000141370.1
AW551984

expressed sequence AW551984

chr19_-_7341848 2.919 ENSMUST00000171393.1
Mark2
MAP/microtubule affinity-regulating kinase 2
chr16_+_26463135 2.897 ENSMUST00000161053.1
ENSMUST00000115302.1
Cldn16

claudin 16

chr9_+_43310763 2.763 ENSMUST00000034511.5
Trim29
tripartite motif-containing 29
chr3_-_144819494 2.751 ENSMUST00000029929.7
Clca2
chloride channel calcium activated 2
chr11_+_96323253 2.733 ENSMUST00000093944.3
Hoxb3
homeobox B3
chr9_-_42124276 2.724 ENSMUST00000060989.8
Sorl1
sortilin-related receptor, LDLR class A repeats-containing
chr14_+_34053466 2.712 ENSMUST00000058725.3
Antxrl
anthrax toxin receptor-like
chr5_-_24030649 2.701 ENSMUST00000030849.6
Fam126a
family with sequence similarity 126, member A
chr4_-_88033328 2.698 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr18_-_32036941 2.697 ENSMUST00000134663.1
Myo7b
myosin VIIB
chr14_+_26894557 2.666 ENSMUST00000090337.4
ENSMUST00000165929.2
Asb14

ankyrin repeat and SOCS box-containing 14

chr8_+_57455898 2.650 ENSMUST00000034023.3
Scrg1
scrapie responsive gene 1
chr9_-_123678873 2.642 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr15_+_85510812 2.598 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr4_-_136602641 2.505 ENSMUST00000105847.1
ENSMUST00000116273.2
Kdm1a

lysine (K)-specific demethylase 1A

chr3_+_122044428 2.453 ENSMUST00000013995.8
Abca4
ATP-binding cassette, sub-family A (ABC1), member 4
chr15_-_79062866 2.451 ENSMUST00000151889.1
ENSMUST00000040676.4
Ankrd54

ankyrin repeat domain 54

chr9_-_123678782 2.450 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr19_+_60755947 2.427 ENSMUST00000088237.4
Nanos1
nanos homolog 1 (Drosophila)
chr7_+_25306085 2.419 ENSMUST00000119703.1
ENSMUST00000108409.1
Tmem145

transmembrane protein 145

chr11_-_120549695 2.403 ENSMUST00000034913.4
Fam195b
family with sequence similarity 195, member B
chr10_-_13324160 2.351 ENSMUST00000105545.4
Phactr2
phosphatase and actin regulator 2
chr18_-_15063560 2.328 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1
chr18_+_21072329 2.300 ENSMUST00000082235.4
Mep1b
meprin 1 beta
chr7_+_66109474 2.285 ENSMUST00000036372.6
Chsy1
chondroitin sulfate synthase 1
chrX_+_56447965 2.247 ENSMUST00000079663.6
Gm2174
predicted gene 2174
chr16_-_76022266 2.230 ENSMUST00000114240.1
Samsn1
SAM domain, SH3 domain and nuclear localization signals, 1
chr17_-_35074485 2.223 ENSMUST00000007259.3
Ly6g6d
lymphocyte antigen 6 complex, locus G6D
chr11_+_96316684 2.112 ENSMUST00000049241.7
Hoxb4
homeobox B4
chr3_+_84666192 2.101 ENSMUST00000107682.1
Tmem154
transmembrane protein 154
chr9_+_110763646 2.093 ENSMUST00000079784.7
Myl3
myosin, light polypeptide 3
chr6_-_83536215 2.058 ENSMUST00000075161.5
Actg2
actin, gamma 2, smooth muscle, enteric
chr10_+_37139558 2.041 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr15_-_101491509 2.014 ENSMUST00000023718.7
5430421N21Rik
RIKEN cDNA 5430421N21 gene
chrX_+_153139941 1.967 ENSMUST00000039720.4
ENSMUST00000144175.2
Rragb

Ras-related GTP binding B

chr10_+_69787431 1.966 ENSMUST00000183240.1
Ank3
ankyrin 3, epithelial
chr7_-_135528645 1.957 ENSMUST00000053716.7
Clrn3
clarin 3
chr16_+_10812915 1.930 ENSMUST00000115822.1
Gm11172
predicted gene 11172
chr11_-_109472611 1.915 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr11_-_17008647 1.914 ENSMUST00000102881.3
Plek
pleckstrin
chr4_+_5724304 1.861 ENSMUST00000108380.1
Fam110b
family with sequence similarity 110, member B
chr7_-_30612731 1.819 ENSMUST00000006476.4
Upk1a
uroplakin 1A
chr2_-_84822546 1.812 ENSMUST00000028471.5
Smtnl1
smoothelin-like 1
chr7_+_131032061 1.793 ENSMUST00000084509.3
Dmbt1
deleted in malignant brain tumors 1
chr17_-_78906899 1.760 ENSMUST00000042683.6
ENSMUST00000169544.1
Sult6b1

sulfotransferase family, cytosolic, 6B, member 1

chr16_+_37011758 1.758 ENSMUST00000071452.5
ENSMUST00000054034.6
Polq

polymerase (DNA directed), theta

chr6_-_87981482 1.743 ENSMUST00000056403.5
H1fx
H1 histone family, member X
chr17_-_70998010 1.732 ENSMUST00000024846.6
Myl12a
myosin, light chain 12A, regulatory, non-sarcomeric
chr14_+_56042123 1.717 ENSMUST00000015576.4
Mcpt2
mast cell protease 2
chr11_+_29463735 1.693 ENSMUST00000155854.1
Ccdc88a
coiled coil domain containing 88A
chr6_-_52218686 1.689 ENSMUST00000134367.2
Hoxa7
homeobox A7
chr6_-_12749193 1.679 ENSMUST00000046121.6
ENSMUST00000172356.1
Thsd7a

thrombospondin, type I, domain containing 7A

chr6_-_13839916 1.677 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chr2_+_57997884 1.653 ENSMUST00000112616.1
ENSMUST00000166729.1
Galnt5

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5

chr4_-_64046925 1.647 ENSMUST00000107377.3
Tnc
tenascin C
chr10_+_116177351 1.637 ENSMUST00000155606.1
ENSMUST00000128399.1
Ptprr

protein tyrosine phosphatase, receptor type, R

chr1_-_172027251 1.544 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr9_-_64172879 1.519 ENSMUST00000176299.1
ENSMUST00000130127.1
ENSMUST00000176794.1
ENSMUST00000177045.1
Zwilch



zwilch kinetochore protein



chr6_+_125552948 1.499 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr10_-_30655859 1.494 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr18_-_6490808 1.491 ENSMUST00000028100.6
ENSMUST00000050542.5
Epc1

enhancer of polycomb homolog 1 (Drosophila)

chr3_-_49757257 1.478 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr2_-_170194033 1.475 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr6_-_122340499 1.464 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr19_+_33822908 1.444 ENSMUST00000042061.6
Gm5519
predicted pseudogene 5519
chr6_-_122340525 1.433 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chr17_-_51826562 1.415 ENSMUST00000024720.4
ENSMUST00000129667.1
ENSMUST00000156051.1
ENSMUST00000169480.1
ENSMUST00000148559.1
Satb1




special AT-rich sequence binding protein 1




chr8_-_57653023 1.397 ENSMUST00000034021.5
Galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr17_+_80307396 1.385 ENSMUST00000068175.5
Arhgef33
Rho guanine nucleotide exchange factor (GEF) 33
chr4_-_133967893 1.356 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr2_-_114013619 1.325 ENSMUST00000090275.4
Gjd2
gap junction protein, delta 2
chr19_-_50678642 1.294 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr8_+_25720054 1.294 ENSMUST00000068916.8
ENSMUST00000139836.1
Ppapdc1b

phosphatidic acid phosphatase type 2 domain containing 1B

chr13_+_19214103 1.290 ENSMUST00000103558.1
Tcrg-C1
T cell receptor gamma, constant 1
chr4_-_11981265 1.264 ENSMUST00000098260.2
Gm10604
predicted gene 10604
chr8_+_121116163 1.260 ENSMUST00000054691.6
Foxc2
forkhead box C2
chr6_-_24168083 1.257 ENSMUST00000031713.8
Slc13a1
solute carrier family 13 (sodium/sulfate symporters), member 1
chrX_+_56779437 1.239 ENSMUST00000114773.3
Fhl1
four and a half LIM domains 1
chr7_+_46861203 1.230 ENSMUST00000014545.4
Ldhc
lactate dehydrogenase C
chr18_+_69593361 1.229 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr1_-_152625212 1.226 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr18_-_62756275 1.210 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr16_-_56795823 1.195 ENSMUST00000023437.4
Gpr128
G protein-coupled receptor 128
chr14_+_76504185 1.176 ENSMUST00000177207.1
Tsc22d1
TSC22 domain family, member 1
chr1_-_128328311 1.151 ENSMUST00000073490.6
Lct
lactase
chr18_-_47333311 1.141 ENSMUST00000126684.1
ENSMUST00000156422.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr8_+_57320975 1.140 ENSMUST00000040104.3
Hand2
heart and neural crest derivatives expressed transcript 2
chr14_+_20674311 1.116 ENSMUST00000048657.8
Sec24c
Sec24 related gene family, member C (S. cerevisiae)
chr1_+_58646608 1.109 ENSMUST00000081455.4
Gm10068
predicted gene 10068
chr3_-_89960562 1.108 ENSMUST00000069805.7
Atp8b2
ATPase, class I, type 8B, member 2
chr1_-_128102412 1.104 ENSMUST00000112538.1
ENSMUST00000086614.5
Zranb3

zinc finger, RAN-binding domain containing 3

chrX_-_74246534 1.097 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr4_-_133967953 1.083 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr1_-_175688353 1.074 ENSMUST00000104984.1
Chml
choroideremia-like
chr5_+_137641334 1.046 ENSMUST00000177466.1
ENSMUST00000166099.2
Sap25

sin3 associated polypeptide

chr13_-_58354862 1.036 ENSMUST00000043605.5
Kif27
kinesin family member 27
chr15_-_34356421 1.028 ENSMUST00000179647.1
9430069I07Rik
RIKEN cDNA 9430069I07 gene
chrX_+_13632769 0.993 ENSMUST00000096492.3
Gpr34
G protein-coupled receptor 34
chr11_-_19018956 0.986 ENSMUST00000068264.7
ENSMUST00000144988.1
ENSMUST00000185131.1
Meis1


Meis homeobox 1


chr14_-_106101157 0.963 ENSMUST00000169588.1
Gm4775
predicted gene 4775
chr1_-_37496095 0.952 ENSMUST00000148047.1
ENSMUST00000143636.1
Mgat4a

mannoside acetylglucosaminyltransferase 4, isoenzyme A

chr11_-_19018714 0.923 ENSMUST00000177417.1
Meis1
Meis homeobox 1
chr2_-_140671462 0.903 ENSMUST00000110057.2
Flrt3
fibronectin leucine rich transmembrane protein 3
chr15_-_42676967 0.900 ENSMUST00000022921.5
Angpt1
angiopoietin 1
chr11_-_100105626 0.899 ENSMUST00000107416.2
Krt36
keratin 36
chr2_+_36230426 0.864 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr15_+_11000716 0.860 ENSMUST00000117100.1
ENSMUST00000022851.7
Slc45a2

solute carrier family 45, member 2

chr17_+_35059035 0.852 ENSMUST00000007255.6
ENSMUST00000174493.1
Ddah2

dimethylarginine dimethylaminohydrolase 2

chr1_-_172027269 0.841 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr15_+_100761741 0.829 ENSMUST00000023776.6
Slc4a8
solute carrier family 4 (anion exchanger), member 8
chr9_-_21067093 0.829 ENSMUST00000115494.2
Zglp1
zinc finger, GATA-like protein 1
chr6_-_145047725 0.826 ENSMUST00000123930.1
Bcat1
branched chain aminotransferase 1, cytosolic
chr6_+_125215551 0.823 ENSMUST00000032487.7
ENSMUST00000100942.2
ENSMUST00000063588.8
Vamp1


vesicle-associated membrane protein 1


chr8_+_15057646 0.807 ENSMUST00000033842.3
Myom2
myomesin 2
chr1_-_176807124 0.787 ENSMUST00000057037.7
Cep170
centrosomal protein 170
chr11_-_97700327 0.785 ENSMUST00000018681.7
Pcgf2
polycomb group ring finger 2
chrY_-_79667079 0.775 ENSMUST00000178903.1
Gm21242
predicted gene, 21242
chr3_-_63851251 0.775 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr15_-_98934522 0.767 ENSMUST00000077577.7
Tuba1b
tubulin, alpha 1B
chr15_+_6422240 0.767 ENSMUST00000163082.1
Dab2
disabled 2, mitogen-responsive phosphoprotein
chr10_+_116177217 0.755 ENSMUST00000148731.1
Ptprr
protein tyrosine phosphatase, receptor type, R
chr2_-_140671400 0.753 ENSMUST00000056760.3
Flrt3
fibronectin leucine rich transmembrane protein 3
chr11_-_109473220 0.731 ENSMUST00000070872.6
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr1_-_144249134 0.713 ENSMUST00000172388.1
Rgs1
regulator of G-protein signaling 1
chr8_-_47352348 0.705 ENSMUST00000110367.2
Stox2
storkhead box 2
chr4_+_136284708 0.703 ENSMUST00000130223.1
Zfp46
zinc finger protein 46
chr3_-_89349968 0.698 ENSMUST00000074582.6
ENSMUST00000107448.2
ENSMUST00000029676.5
Adam15


a disintegrin and metallopeptidase domain 15 (metargidin)


chr17_-_15826521 0.694 ENSMUST00000170578.1
Rgmb
RGM domain family, member B
chr1_+_164048214 0.691 ENSMUST00000027874.5
Sele
selectin, endothelial cell
chr11_+_98026918 0.690 ENSMUST00000017548.6
Rpl19
ribosomal protein L19
chr11_+_96282529 0.672 ENSMUST00000125410.1
Hoxb8
homeobox B8
chr3_-_87768966 0.661 ENSMUST00000174776.1
Pear1
platelet endothelial aggregation receptor 1
chr11_+_96282648 0.649 ENSMUST00000168043.1
Hoxb8
homeobox B8
chr16_+_45224315 0.643 ENSMUST00000102802.3
ENSMUST00000063654.4
Btla

B and T lymphocyte associated

chrX_+_150547375 0.642 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr3_-_19265007 0.641 ENSMUST00000091314.4
Pde7a
phosphodiesterase 7A
chr6_-_132957919 0.640 ENSMUST00000082085.4
Tas2r131
taste receptor, type 2, member 131
chr6_-_52234902 0.639 ENSMUST00000125581.1
Hoxa10
homeobox A10
chr2_-_45112890 0.635 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr2_-_27463994 0.634 ENSMUST00000164296.1
Brd3
bromodomain containing 3
chr3_-_89349939 0.632 ENSMUST00000107446.1
Adam15
a disintegrin and metallopeptidase domain 15 (metargidin)
chr7_-_119459266 0.630 ENSMUST00000033255.5
Gp2
glycoprotein 2 (zymogen granule membrane)
chr5_+_31054766 0.624 ENSMUST00000013773.5
ENSMUST00000114646.1
Cad

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

chrX_-_12673540 0.605 ENSMUST00000060108.6
1810030O07Rik
RIKEN cDNA 1810030O07 gene
chr3_+_3634145 0.604 ENSMUST00000108394.1
Hnf4g
hepatocyte nuclear factor 4, gamma
chr6_-_87335758 0.602 ENSMUST00000042025.9
Antxr1
anthrax toxin receptor 1
chr4_+_108479081 0.597 ENSMUST00000155068.1
Zcchc11
zinc finger, CCHC domain containing 11
chr13_-_101692624 0.593 ENSMUST00000035532.6
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chrX_+_111168340 0.588 ENSMUST00000075226.4
Gm10112
predicted pseudogene 10112
chr5_+_150259922 0.588 ENSMUST00000087204.5
Fry
furry homolog (Drosophila)
chr1_-_120270253 0.588 ENSMUST00000112639.1
Steap3
STEAP family member 3
chr11_-_100146120 0.586 ENSMUST00000007317.7
Krt19
keratin 19

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 14.3 GO:0045575 basophil activation(GO:0045575)
3.3 26.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.6 6.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.4 4.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
1.4 4.1 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
1.4 6.8 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
1.0 3.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.0 4.1 GO:0015827 tryptophan transport(GO:0015827)
1.0 1.9 GO:0070560 protein secretion by platelet(GO:0070560)
0.8 2.5 GO:0046098 guanine metabolic process(GO:0046098)
0.8 8.3 GO:0090527 actin filament reorganization(GO:0090527)
0.8 2.4 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.7 2.7 GO:2001137 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) positive regulation of endocytic recycling(GO:2001137)
0.7 5.3 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.7 10.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.6 1.8 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.5 2.7 GO:1904970 brush border assembly(GO:1904970)
0.5 5.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.4 1.3 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.4 1.6 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.4 2.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.4 2.6 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.4 1.1 GO:0036292 DNA rewinding(GO:0036292)
0.4 1.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.3 1.7 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.3 4.8 GO:0042118 endothelial cell activation(GO:0042118)
0.3 0.9 GO:0030210 heparin biosynthetic process(GO:0030210)
0.3 3.2 GO:0035092 sperm chromatin condensation(GO:0035092)
0.3 4.0 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.3 9.0 GO:0006825 copper ion transport(GO:0006825)
0.3 3.8 GO:0048664 neuron fate determination(GO:0048664)
0.2 1.2 GO:0019516 lactate oxidation(GO:0019516)
0.2 3.9 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 2.1 GO:0048539 bone marrow development(GO:0048539)
0.2 3.0 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.2 2.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 1.1 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.2 1.4 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 0.4 GO:0033561 regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.2 0.9 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.2 3.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 2.0 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.2 1.2 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.2 1.2 GO:0010288 response to lead ion(GO:0010288)
0.2 2.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.2 2.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 0.5 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.2 5.3 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.7 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 1.8 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.6 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.1 0.6 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.1 1.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.6 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.5 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.1 0.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.3 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.9 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.6 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 6.1 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.1 1.7 GO:0001525 angiogenesis(GO:0001525)
0.1 5.8 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 1.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 1.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.9 GO:0000052 citrulline metabolic process(GO:0000052)
0.1 1.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 1.3 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 1.0 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.9 GO:0035855 megakaryocyte development(GO:0035855)
0.1 1.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.2 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 2.9 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.1 8.2 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 0.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 2.5 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 2.2 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 5.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 1.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 1.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 2.3 GO:0019236 response to pheromone(GO:0019236)
0.1 1.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 1.3 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 0.6 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.1 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 3.8 GO:0045332 phospholipid translocation(GO:0045332)
0.1 2.1 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 0.9 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1 4.5 GO:0030239 myofibril assembly(GO:0030239)
0.1 0.2 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1 0.6 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 1.1 GO:0014823 response to activity(GO:0014823)
0.1 2.9 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.5 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 1.1 GO:0045616 regulation of keratinocyte differentiation(GO:0045616)
0.0 5.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.5 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.8 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.5 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 1.0 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 1.7 GO:0072659 protein localization to plasma membrane(GO:0072659)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.3 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.2 GO:0098532 nucleosome positioning(GO:0016584) histone H3-K27 trimethylation(GO:0098532)
0.0 1.3 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 2.1 GO:0045471 response to ethanol(GO:0045471)
0.0 2.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.3 GO:0014029 neural crest formation(GO:0014029)
0.0 0.8 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 1.4 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.0 1.3 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.2 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.3 GO:0034391 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 2.7 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.0 0.1 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.8 GO:0048599 oocyte development(GO:0048599)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 1.2 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.2 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.4 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 0.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 1.2 GO:0030168 platelet activation(GO:0030168)
0.0 1.1 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.3 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.1 GO:1900003 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.1 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:0048679 regulation of axon regeneration(GO:0048679)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 1.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.3 GO:0001508 action potential(GO:0001508)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 1.3 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 3.2 GO:0016358 dendrite development(GO:0016358)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.3 GO:0005588 collagen type V trimer(GO:0005588)
0.7 5.9 GO:0097427 microtubule bundle(GO:0097427)
0.7 3.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.6 2.4 GO:0060187 cell pole(GO:0060187)
0.6 15.7 GO:0032982 myosin filament(GO:0032982)
0.5 1.5 GO:1990423 RZZ complex(GO:1990423)
0.5 1.8 GO:0120001 apical plasma membrane urothelial plaque(GO:0120001)
0.4 2.0 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3 4.9 GO:0042589 zymogen granule membrane(GO:0042589)
0.3 1.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 4.1 GO:0070852 cell body fiber(GO:0070852)
0.2 1.1 GO:0031523 Myb complex(GO:0031523)
0.2 1.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 0.8 GO:0070820 tertiary granule(GO:0070820)
0.2 3.7 GO:0035102 PRC1 complex(GO:0035102)
0.2 0.8 GO:0070022 transforming growth factor beta receptor complex(GO:0070022)
0.2 0.5 GO:0072534 perineuronal net(GO:0072534)
0.2 2.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 2.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.8 GO:0098936 intrinsic component of postsynaptic membrane(GO:0098936) integral component of postsynaptic membrane(GO:0099055) intrinsic component of synaptic membrane(GO:0099240) integral component of synaptic membrane(GO:0099699)
0.1 2.5 GO:0016460 myosin II complex(GO:0016460)
0.1 2.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.6 GO:1990357 terminal web(GO:1990357)
0.1 0.5 GO:0001740 Barr body(GO:0001740)
0.1 4.4 GO:0016235 aggresome(GO:0016235)
0.1 3.1 GO:0031672 A band(GO:0031672)
0.1 6.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 0.6 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 1.3 GO:0005922 connexin complex(GO:0005922)
0.1 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 2.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 2.3 GO:1990391 DNA repair complex(GO:1990391)
0.0 12.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 5.1 GO:0055037 recycling endosome(GO:0055037)
0.0 0.4 GO:0000243 commitment complex(GO:0000243)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.0 3.6 GO:0030018 Z disc(GO:0030018)
0.0 1.2 GO:0071162 nuclear replication fork(GO:0043596) CMG complex(GO:0071162)
0.0 4.2 GO:0005903 brush border(GO:0005903)
0.0 0.8 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 2.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.9 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.3 GO:0005581 collagen trimer(GO:0005581)
0.0 2.0 GO:0016363 nuclear matrix(GO:0016363)
0.0 3.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0005771 multivesicular body(GO:0005771)
0.0 1.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.7 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.6 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.7 GO:0005905 clathrin-coated pit(GO:0005905)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 26.0 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
1.4 4.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
1.4 4.1 GO:0001587 Gq/11-coupled serotonin receptor activity(GO:0001587)
1.4 6.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.9 4.4 GO:0051373 FATZ binding(GO:0051373)
0.8 8.5 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.8 2.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.8 5.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.6 4.4 GO:0016936 galactoside binding(GO:0016936)
0.6 4.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.6 10.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.5 2.5 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.5 5.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.5 2.7 GO:1902944 aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902944)
0.4 2.5 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.4 1.2 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.3 1.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 6.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229) intracellular chloride channel activity(GO:0061778)
0.3 4.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.3 0.8 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.2 2.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 1.4 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 1.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.2 0.9 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 0.6 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 1.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 6.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 5.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.2 1.6 GO:0045545 syndecan binding(GO:0045545)
0.2 1.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.2 1.8 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.2 3.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.6 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 3.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.9 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 6.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.6 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.9 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 16.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.7 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 1.9 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.1 1.8 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 9.9 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 1.1 GO:0036310 annealing helicase activity(GO:0036310)
0.1 1.8 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.1 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 1.5 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.7 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.8 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 8.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 0.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.9 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.6 GO:0000293 ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.8 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 1.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.7 GO:0043422 protein kinase B binding(GO:0043422)
0.1 1.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.3 GO:0008061 chitin binding(GO:0008061)
0.1 5.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 1.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 2.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 13.1 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 2.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 7.6 GO:0003774 motor activity(GO:0003774)
0.0 0.7 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 1.0 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.5 GO:0046625 sphingolipid binding(GO:0046625)
0.0 1.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 2.5 GO:0001784 phosphotyrosine residue binding(GO:0001784)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.7 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577) acetylation-dependent protein binding(GO:0140033)
0.0 1.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0032564 dATP binding(GO:0032564)
0.0 1.8 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 2.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.9 GO:0046332 SMAD binding(GO:0046332)
0.0 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0031489 myosin V binding(GO:0031489)
0.0 1.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 2.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.5 GO:0008083 growth factor activity(GO:0008083)
0.0 2.2 GO:0003714 transcription corepressor activity(GO:0003714)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 28.1 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.3 10.3 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.3 12.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.3 5.3 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 5.1 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.1 8.1 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 3.2 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.6 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 2.1 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 0.6 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 7.6 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.3 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.8 PID_P73PATHWAY p73 transcription factor network
0.0 4.8 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.9 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.5 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.5 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 1.2 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.3 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 2.6 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.1 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.3 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.5 PID_IL4_2PATHWAY IL4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 26.0 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4 5.3 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.4 4.1 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.2 8.5 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 2.3 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.5 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 5.1 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.3 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.3 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 2.9 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 1.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.5 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 0.8 REACTOME_GAP_JUNCTION_TRAFFICKING Genes involved in Gap junction trafficking
0.1 0.8 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.1 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.9 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 3.1 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 7.7 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.8 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 2.1 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.8 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.7 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 4.6 REACTOME_TRANSLATION Genes involved in Translation
0.0 0.6 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.9 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 1.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.7 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.5 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.6 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.3 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 0.0 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.4 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION Genes involved in Glucagon signaling in metabolic regulation