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GSE58827: Dynamics of the Mouse Liver

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Results for Hoxd8

Z-value: 0.66

Motif logo

Transcription factors associated with Hoxd8

Gene Symbol Gene ID Gene Info
ENSMUSG00000027102.4 homeobox D8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxd8mm10_v2_chr2_+_74705145_74705156-0.281.0e-01Click!

Activity profile of Hoxd8 motif

Sorted Z-values of Hoxd8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_122006798 3.37 ENSMUST00000081777.6
murinoglobulin 2
chr19_-_46672883 2.23 ENSMUST00000026012.7
cytochrome P450, family 17, subfamily a, polypeptide 1
chr5_-_87591582 1.48 ENSMUST00000031201.7
sulfotransferase family 1E, member 1
chr5_-_87337165 1.44 ENSMUST00000031195.2
UDP glucuronosyltransferase 2 family, polypeptide A3
chr8_+_46010596 1.25 ENSMUST00000110381.2
Lrp2 binding protein
chr5_+_29195983 1.20 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
ring finger protein 32
chr1_-_187215454 1.10 ENSMUST00000183819.1
spermatogenesis associated 17
chr19_+_24875679 1.10 ENSMUST00000073080.5
predicted gene 10053
chr9_+_80165013 0.99 ENSMUST00000035889.8
ENSMUST00000113268.1
myosin VI
chr2_+_163472545 0.93 ENSMUST00000065731.4
RIKEN cDNA 2310001K24 gene
chr1_-_138848576 0.90 ENSMUST00000112030.2
LIM homeobox protein 9
chr3_-_96452306 0.89 ENSMUST00000093126.4
ENSMUST00000098841.3
cDNA sequence BC107364
chr1_+_9547948 0.83 ENSMUST00000144177.1
alcohol dehydrogenase, iron containing, 1
chr11_+_117809653 0.82 ENSMUST00000026649.7
ENSMUST00000177131.1
ENSMUST00000132298.1
synaptogyrin 2
predicted gene 20708
chr9_-_15301555 0.77 ENSMUST00000034414.8
RIKEN cDNA 4931406C07 gene
chr5_-_31295862 0.76 ENSMUST00000041266.7
ENSMUST00000172435.1
fibronectin type III domain containing 4
chr2_-_148038270 0.75 ENSMUST00000132070.1
RIKEN cDNA 9030622O22 gene
chr3_-_144849301 0.75 ENSMUST00000159989.1
chloride channel calcium activated 4
chr1_+_88166004 0.75 ENSMUST00000097659.4
UDP glucuronosyltransferase 1 family, polypeptide A5
chr1_-_187215421 0.75 ENSMUST00000110945.3
ENSMUST00000183931.1
ENSMUST00000027908.6
spermatogenesis associated 17
chr14_+_55559993 0.73 ENSMUST00000117236.1
DDB1 and CUL4 associated factor 11
chr5_+_87000838 0.72 ENSMUST00000031186.7
UDP glucuronosyltransferase 2 family, polypeptide B35
chr1_+_177729814 0.69 ENSMUST00000016106.5
RIKEN cDNA 1700016C15 gene
chr6_+_71282280 0.64 ENSMUST00000080949.7
lysine-rich coiled-coil 1
chr2_+_152669461 0.63 ENSMUST00000125366.1
ENSMUST00000109825.1
ENSMUST00000089059.2
ENSMUST00000079247.3
histocompatibility 13
chr14_+_47298260 0.62 ENSMUST00000166743.1
mitogen-activated protein kinase 1 interacting protein 1-like
chr16_+_11406618 0.61 ENSMUST00000122168.1
sorting nexin 29
chr14_+_55560010 0.57 ENSMUST00000147981.1
ENSMUST00000133256.1
DDB1 and CUL4 associated factor 11
chr3_+_94372794 0.57 ENSMUST00000029795.3
RAR-related orphan receptor gamma
chr13_-_85127514 0.57 ENSMUST00000179230.1
predicted gene 4076
chr11_+_117809687 0.56 ENSMUST00000120928.1
ENSMUST00000175737.1
synaptogyrin 2
chr18_-_38866702 0.55 ENSMUST00000115582.1
fibroblast growth factor 1
chrX_-_160138375 0.54 ENSMUST00000033662.8
pyruvate dehydrogenase E1 alpha 1
chr12_+_31390843 0.54 ENSMUST00000167432.1
solute carrier family 26, member 3
chr5_-_121527186 0.53 ENSMUST00000152270.1
MAP kinase-activated protein kinase 5
chr9_+_54538984 0.51 ENSMUST00000060242.5
ENSMUST00000118413.1
SH2 domain containing 7
chr11_+_99873389 0.50 ENSMUST00000093936.3
keratin associated protein 9-1
chr5_-_103629279 0.50 ENSMUST00000031263.1
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr3_-_19264959 0.50 ENSMUST00000121951.1
phosphodiesterase 7A
chr7_-_99980431 0.50 ENSMUST00000080817.4
ring finger protein 169
chr13_+_23839445 0.49 ENSMUST00000091698.4
ENSMUST00000110422.1
solute carrier family 17 (sodium phosphate), member 3
chr11_+_78037959 0.49 ENSMUST00000073660.6
flotillin 2
chr11_+_78037931 0.48 ENSMUST00000072289.5
ENSMUST00000100784.2
flotillin 2
chr2_-_89024099 0.47 ENSMUST00000099799.2
olfactory receptor 1217
chrY_+_80135210 0.47 ENSMUST00000179811.1
predicted gene, 21760
chr1_+_88306731 0.46 ENSMUST00000040210.7
transient receptor potential cation channel, subfamily M, member 8
chr9_+_80165079 0.46 ENSMUST00000184480.1
myosin VI
chr4_-_108301045 0.45 ENSMUST00000043616.6
zyg-ll family member B, cell cycle regulator
chr2_+_110597298 0.45 ENSMUST00000045972.6
ENSMUST00000111026.2
solute carrier family 5 (sodium/glucose cotransporter), member 12
chrY_-_35920097 0.44 ENSMUST00000180332.1
predicted gene, 20896
chrY_+_87118255 0.44 ENSMUST00000179970.1
predicted gene, 21477
chrY_+_84098711 0.44 ENSMUST00000177775.1
predicted gene, 21095
chrY_+_54656891 0.44 ENSMUST00000179631.1
predicted gene, 21894
chr13_+_23839401 0.43 ENSMUST00000039721.7
ENSMUST00000166467.1
solute carrier family 17 (sodium phosphate), member 3
chrY_+_55215153 0.42 ENSMUST00000180249.1
predicted gene, 20931
chr6_+_134640940 0.42 ENSMUST00000062755.8
loss of heterozygosity, 12, chromosomal region 1 homolog (human)
chr3_-_95871367 0.42 ENSMUST00000142437.1
ENSMUST00000067298.4
mitochondrial ribosomal protein S21
chr7_+_126976338 0.41 ENSMUST00000032920.3
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr3_-_116712644 0.40 ENSMUST00000029569.2
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chrY_+_79320997 0.40 ENSMUST00000178063.1
predicted gene, 20916
chr4_+_101986626 0.40 ENSMUST00000106914.1
predicted gene 12789
chr18_-_73754457 0.39 ENSMUST00000041138.2
elaC homolog 1 (E. coli)
chr9_-_57158288 0.38 ENSMUST00000065358.7
COMM domain containing 4
chr2_-_151668533 0.38 ENSMUST00000180195.1
ENSMUST00000096439.3
RAD21-like (S. pombe)
chr12_+_72536342 0.37 ENSMUST00000044352.6
pecanex-like 4 (Drosophila)
chr15_-_103565069 0.37 ENSMUST00000023134.3
glycosylation dependent cell adhesion molecule 1
chr8_-_64987646 0.37 ENSMUST00000095295.1
tripartite motif-containing 75
chr10_+_103367748 0.36 ENSMUST00000074204.4
ENSMUST00000179636.1
solute carrier family 6 (neurotransmitter transporter), member 15
chr10_+_116177217 0.35 ENSMUST00000148731.1
protein tyrosine phosphatase, receptor type, R
chr1_-_179745185 0.35 ENSMUST00000131716.1
predicted gene 1305
chr12_-_90969768 0.34 ENSMUST00000181184.1
RIKEN cDNA 4930544I03 gene
chr3_+_127633134 0.33 ENSMUST00000029587.7
neurogenin 2
chr9_+_75051977 0.33 ENSMUST00000170310.1
ENSMUST00000166549.1
cAMP-regulated phosphoprotein 19
chrY_-_35130404 0.33 ENSMUST00000180170.1
predicted gene, 20855
chrM_+_7759 0.33 ENSMUST00000082407.1
ENSMUST00000082408.1
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr11_+_99857915 0.33 ENSMUST00000107434.1
predicted gene 11568
chr1_-_141257158 0.32 ENSMUST00000179202.1
predicted gene 4845
chr5_+_48372363 0.32 ENSMUST00000030968.2
PARK2 co-regulated-like
chr10_+_117045341 0.31 ENSMUST00000073834.4
leucine rich repeat containing 10
chr8_-_84662841 0.31 ENSMUST00000060427.4
immediate early response 2
chr17_-_34862473 0.29 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
complement factor B
chr4_+_118961578 0.29 ENSMUST00000058651.4
L-amino acid oxidase 1
chr9_-_55512156 0.28 ENSMUST00000034866.8
electron transferring flavoprotein, alpha polypeptide
chr2_-_73580288 0.28 ENSMUST00000028515.3
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr7_-_103788275 0.27 ENSMUST00000183254.1
olfactory receptor 67
chr1_-_127840290 0.27 ENSMUST00000061512.2
mitogen-activated protein kinase kinase kinase 19
chr19_-_19001099 0.27 ENSMUST00000040153.8
ENSMUST00000112828.1
RAR-related orphan receptor beta
chr11_-_100088226 0.27 ENSMUST00000107419.1
keratin 32
chr9_-_118014160 0.26 ENSMUST00000111769.3
zinc finger, CW type with PWWP domain 2
chr4_+_145670685 0.26 ENSMUST00000105738.2
predicted gene 13242
chr8_+_21839926 0.26 ENSMUST00000006745.3
defensin beta 2
chr3_-_96197580 0.26 ENSMUST00000016087.3
bolA-like 1 (E. coli)
chr8_-_21906412 0.25 ENSMUST00000051965.4
defensin beta 11
chr14_+_58893465 0.25 ENSMUST00000079960.1
ribosomal protein L13, pseudogene 3
chr15_-_57265126 0.25 ENSMUST00000137764.1
ENSMUST00000022995.6
solute carrier family 22 (organic cation transporter), member 22
chr5_-_92215345 0.24 ENSMUST00000031356.4
cDNA sequence U90926
chr1_+_178798438 0.23 ENSMUST00000160789.1
kinesin family member 26B
chr7_+_18245347 0.23 ENSMUST00000066780.4
MHC I like leukocyte 1
chr12_+_87443896 0.23 ENSMUST00000161023.1
ENSMUST00000160488.1
ENSMUST00000077462.7
ENSMUST00000160880.1
SRA stem-loop interacting RNA binding protein
chr11_+_90804682 0.23 ENSMUST00000142521.1
RIKEN cDNA 4930405D11 gene
chr7_-_80405425 0.23 ENSMUST00000107362.3
ENSMUST00000135306.1
furin (paired basic amino acid cleaving enzyme)
chr3_+_88716838 0.23 ENSMUST00000029692.8
ENSMUST00000171645.1
Ras-like without CAAX 1
chr6_-_135310347 0.22 ENSMUST00000050471.2
phosphatidylethanolamine binding protein 2
chrY_+_56502254 0.22 ENSMUST00000178213.1
predicted gene, 21815
chr5_-_90640464 0.22 ENSMUST00000031317.6
Ras association (RalGDS/AF-6) domain family member 6
chr17_+_74489492 0.22 ENSMUST00000024873.6
Yip1 domain family, member 4
chr8_-_106573461 0.22 ENSMUST00000073722.5
predicted pseudogene 10073
chr10_-_103236280 0.22 ENSMUST00000123364.1
ENSMUST00000166240.1
ENSMUST00000020043.5
leucine-rich repeats and IQ motif containing 1
chr3_+_88716884 0.22 ENSMUST00000172252.1
Ras-like without CAAX 1
chr4_-_42459176 0.22 ENSMUST00000098118.1
predicted gene 10597
chr7_+_26757153 0.22 ENSMUST00000077855.6
cytochrome P450, family 2, subfamily b, polypeptide 19
chr3_-_72967854 0.22 ENSMUST00000167334.1
sucrase isomaltase (alpha-glucosidase)
chr12_-_84617326 0.22 ENSMUST00000021666.4
ATP-binding cassette, sub-family D (ALD), member 4
chr17_+_34647128 0.21 ENSMUST00000015605.8
ENSMUST00000182587.1
activating transcription factor 6 beta
chr10_-_25200110 0.21 ENSMUST00000100012.2
A kinase (PRKA) anchor protein 7
chrY_+_55733188 0.21 ENSMUST00000177834.1
predicted gene, 21858
chr18_+_56562443 0.20 ENSMUST00000130163.1
ENSMUST00000132628.1
phosphorylated adaptor for RNA export
chr10_+_116177351 0.20 ENSMUST00000155606.1
ENSMUST00000128399.1
protein tyrosine phosphatase, receptor type, R
chr11_+_73371246 0.20 ENSMUST00000120401.1
ENSMUST00000078952.2
ENSMUST00000170592.1
ENSMUST00000127789.1
olfactory receptor 376
chr10_+_79468943 0.20 ENSMUST00000167976.2
vomeronasal 2, receptor 83
chr7_+_140763739 0.19 ENSMUST00000026552.7
cytochrome P450, family 2, subfamily e, polypeptide 1
chr2_+_151494182 0.19 ENSMUST00000089140.6
NSFL1 (p97) cofactor (p47)
chr1_+_178405881 0.18 ENSMUST00000027775.7
EF-hand calcium binding domain 2
chr5_-_38491948 0.18 ENSMUST00000129099.1
solute carrier family 2 (facilitated glucose transporter), member 9
chr11_-_99374895 0.17 ENSMUST00000006963.2
keratin 28
chr2_-_163472561 0.17 ENSMUST00000109418.1
fat storage-inducing transmembrane protein 2
chr2_+_152687137 0.17 ENSMUST00000062148.6
malignant T cell amplified sequence 2
chr17_+_34647187 0.17 ENSMUST00000173984.1
activating transcription factor 6 beta
chr9_+_54980880 0.16 ENSMUST00000093844.3
cholinergic receptor, nicotinic, alpha polypeptide 5
chr7_-_45062393 0.16 ENSMUST00000129101.1
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr14_+_69347587 0.16 ENSMUST00000064831.5
ectonucleoside triphosphate diphosphohydrolase 4
chr3_+_106034661 0.16 ENSMUST00000170669.2
predicted gene 4540
chr13_-_62888282 0.16 ENSMUST00000092888.4
fructose bisphosphatase 1
chr5_-_62766153 0.15 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_+_65282056 0.15 ENSMUST00000140190.1
parathyroid hormone 2 receptor
chr2_+_111378967 0.15 ENSMUST00000062407.2
olfactory receptor 1284
chr14_-_118735143 0.15 ENSMUST00000184172.1
RP24-241I19.1
chr10_-_63927434 0.15 ENSMUST00000079279.3
predicted gene 10118
chr7_-_22229484 0.14 ENSMUST00000167253.1
predicted gene 8453
chr1_-_134549663 0.14 ENSMUST00000172898.1
RIKEN cDNA 4931440L10 gene
chr2_+_88817173 0.13 ENSMUST00000072057.1
olfactory receptor 1202
chr2_+_150190393 0.13 ENSMUST00000109929.2
predicted gene 14139
chr4_+_146971976 0.13 ENSMUST00000146688.2
predicted gene 13150
chr15_-_35155750 0.13 ENSMUST00000067033.7
ENSMUST00000018476.7
serine/threonine kinase 3
chr10_+_116966274 0.12 ENSMUST00000033651.3
RIKEN cDNA D630029K05 gene
chr11_+_16257706 0.12 ENSMUST00000109645.2
ENSMUST00000109647.2
V-set and transmembrane domain containing 2A
chr10_-_127030813 0.12 ENSMUST00000040560.4
Ts translation elongation factor, mitochondrial
chr3_+_24333046 0.11 ENSMUST00000077389.6
predicted gene 7536
chr12_-_54695829 0.11 ENSMUST00000162106.1
ENSMUST00000160085.1
ENSMUST00000161592.1
ENSMUST00000163433.1
E2F-associated phosphoprotein
chr8_+_33599608 0.10 ENSMUST00000009774.9
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
chrY_+_65379124 0.10 ENSMUST00000178198.1
predicted gene, 20736
chr9_+_123774540 0.10 ENSMUST00000180093.1
chemokine (C-C motif) receptor 9
chr19_-_39812744 0.10 ENSMUST00000162507.1
ENSMUST00000160476.1
cytochrome P450, family 2, subfamily c, polypeptide 40
chrY_-_47691098 0.10 ENSMUST00000179330.1
predicted gene, 21170
chrY_-_60481481 0.10 ENSMUST00000177626.1
predicted gene, 20794
chrY_+_58574464 0.09 ENSMUST00000179024.1
predicted gene, 21405
chr11_+_109543694 0.09 ENSMUST00000106696.1
arylsulfatase G
chrY_+_33246466 0.09 ENSMUST00000178380.1
predicted gene, 21756
chrY_+_31373426 0.09 ENSMUST00000178112.1
predicted gene, 21737
chrY_+_52781462 0.09 ENSMUST00000178673.1
predicted gene, 21258
chrY_+_32380234 0.08 ENSMUST00000178403.1
predicted gene, 21744
chr12_-_54695885 0.08 ENSMUST00000067272.8
E2F-associated phosphoprotein
chr10_-_127030789 0.07 ENSMUST00000120547.1
ENSMUST00000152054.1
Ts translation elongation factor, mitochondrial
chrY_+_29351845 0.06 ENSMUST00000180071.1
predicted gene, 21853
chr4_+_52596270 0.06 ENSMUST00000029995.5
RIKEN cDNA 4930547C10 gene
chr11_+_87566653 0.06 ENSMUST00000060360.5
predicted gene 11492
chrY_-_29683370 0.05 ENSMUST00000180373.1
predicted gene, 21679
chrX_-_74393003 0.05 ENSMUST00000015427.6
family with sequence similarity 3, member A
chr19_-_11856001 0.05 ENSMUST00000079875.3
olfactory receptor 1418
chr6_-_132957919 0.05 ENSMUST00000082085.4
taste receptor, type 2, member 131
chr7_-_29906524 0.04 ENSMUST00000159920.1
ENSMUST00000162592.1
zinc finger protein 27
chr3_-_69859875 0.04 ENSMUST00000051239.7
ENSMUST00000171529.1
serine palmitoyltransferase, small subunit B
chr3_-_30140407 0.04 ENSMUST00000108271.3
MDS1 and EVI1 complex locus
chr7_+_103979176 0.03 ENSMUST00000098185.1
olfactory receptor 635
chr5_-_123666682 0.03 ENSMUST00000149410.1
CAP-GLY domain containing linker protein 1
chr3_+_76075583 0.03 ENSMUST00000160261.1
follistatin-like 5
chr7_+_39588931 0.03 ENSMUST00000178791.1
ENSMUST00000098511.3
predicted gene 2058
chr5_+_68031775 0.03 ENSMUST00000094715.4
glutaredoxin, cysteine rich 1
chr3_+_19957240 0.03 ENSMUST00000108325.2
ceruloplasmin
chr17_-_32822200 0.03 ENSMUST00000179695.1
zinc finger protein 799
chrY_-_40315451 0.02 ENSMUST00000177713.1
predicted gene, 21865
chr7_+_45062429 0.02 ENSMUST00000107830.1
ENSMUST00000003513.3
ENSMUST00000107829.1
ENSMUST00000150609.1
nitric oxide synthase interacting protein
chr5_+_65348386 0.02 ENSMUST00000031096.7
klotho beta
chr7_-_20233828 0.01 ENSMUST00000168580.1
predicted gene 4498
chr18_+_44071390 0.01 ENSMUST00000068473.2
serine peptidase inhibitor, Kazal type 6
chrY_+_43953619 0.01 ENSMUST00000179551.1
predicted gene, 21241
chr6_+_24733241 0.01 ENSMUST00000031690.5
hyaluronoglucosaminidase 6
chr2_+_110721587 0.00 ENSMUST00000111017.2
mucin 15

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxd8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.2 1.5 GO:0006068 ethanol catabolic process(GO:0006068)
0.2 0.6 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.2 0.8 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.4 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 2.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 2.2 GO:0042448 progesterone metabolic process(GO:0042448)
0.1 0.6 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 1.4 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 0.6 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.4 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 0.4 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 0.5 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.4 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.2 GO:0051030 snRNA transport(GO:0051030)
0.1 0.9 GO:0015747 urate transport(GO:0015747)
0.1 0.4 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.2 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.1 0.2 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.2 GO:0090472 dibasic protein processing(GO:0090472)
0.1 0.5 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.6 GO:0072615 interleukin-17 secretion(GO:0072615)
0.0 0.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.5 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.5 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.2 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.1 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.0 0.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.5 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.0 0.3 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.3 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 1.0 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:1905034 regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035)
0.0 0.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.5 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 1.0 GO:0001931 uropod(GO:0001931) flotillin complex(GO:0016600) cell trailing edge(GO:0031254)
0.1 0.3 GO:0017133 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 0.4 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 0.2 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.1 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 1.4 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 1.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.5 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 1.3 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 1.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 2.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 0.8 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.9 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.6 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.5 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.3 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 2.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.4 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.4 GO:0043199 sulfate binding(GO:0043199)
0.0 0.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.6 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.4 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.2 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 3.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.4 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.4 GO:0016208 AMP binding(GO:0016208)
0.0 1.0 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.4 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 3.3 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 ST P38 MAPK PATHWAY p38 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.8 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases