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GSE58827: Dynamics of the Mouse Liver

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Results for Hsf2

Z-value: 0.66

Motif logo

Transcription factors associated with Hsf2

Gene Symbol Gene ID Gene Info
ENSMUSG00000019878.7 heat shock factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hsf2mm10_v2_chr10_+_57486354_574864140.173.1e-01Click!

Activity profile of Hsf2 motif

Sorted Z-values of Hsf2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_66935333 2.01 ENSMUST00000120415.1
ENSMUST00000119429.1
myosin, light polypeptide 1
chr4_-_141825997 1.33 ENSMUST00000102481.3
chymotrypsin-like elastase family, member 2A
chr9_+_8544196 1.28 ENSMUST00000050433.6
transient receptor potential cation channel, subfamily C, member 6
chrX_+_21484532 1.24 ENSMUST00000089188.2
angiotensin II receptor, type 2
chr11_-_100121558 1.09 ENSMUST00000007275.2
keratin 13
chr9_+_98490522 1.05 ENSMUST00000035029.2
retinol binding protein 2, cellular
chr13_-_37049203 1.00 ENSMUST00000037491.8
coagulation factor XIII, A1 subunit
chr6_+_41521782 0.91 ENSMUST00000070380.4
protease, serine, 2
chr16_-_36455378 0.81 ENSMUST00000068182.2
stefin A3
chr17_-_31129602 0.81 ENSMUST00000024827.4
trefoil factor 3, intestinal
chr16_-_36367623 0.80 ENSMUST00000096089.2
cDNA sequence BC100530
chr16_+_17980565 0.80 ENSMUST00000075371.3
pre-B lymphocyte gene 2
chr5_+_76656512 0.80 ENSMUST00000086909.4
predicted gene 10430
chrX_+_164090187 0.78 ENSMUST00000015545.3
transmembrane protein 27
chr5_+_135887905 0.73 ENSMUST00000005077.6
heat shock protein 1
chr16_+_36156801 0.72 ENSMUST00000079184.4
stefin A2 like 1
chr19_+_58670358 0.68 ENSMUST00000057270.7
pancreatic lipase
chr7_+_127211608 0.67 ENSMUST00000032910.6
myosin light chain, phosphorylatable, fast skeletal muscle
chr7_-_126463100 0.67 ENSMUST00000032974.6
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr17_+_40811089 0.64 ENSMUST00000024721.7
Rhesus blood group-associated A glycoprotein
chr16_-_36408349 0.64 ENSMUST00000023619.6
stefin A2
chr18_+_36664060 0.63 ENSMUST00000036765.7
eukaryotic translation initiation factor 4E binding protein 3
chr5_+_135887988 0.62 ENSMUST00000111155.1
heat shock protein 1
chr2_+_43748802 0.62 ENSMUST00000112824.1
ENSMUST00000055776.7
Rho GTPase activating protein 15
chrX_+_157702574 0.61 ENSMUST00000112520.1
small muscle protein, X-linked
chr1_-_37496095 0.61 ENSMUST00000148047.1
ENSMUST00000143636.1
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr9_+_72438519 0.59 ENSMUST00000184604.1
meiosis-specific nuclear structural protein 1
chr16_+_36277145 0.59 ENSMUST00000042097.9
stefin A1
chr6_-_78468863 0.59 ENSMUST00000032089.2
regenerating islet-derived 3 gamma
chr12_-_110696248 0.58 ENSMUST00000124156.1
heat shock protein 90, alpha (cytosolic), class A member 1
chr7_+_16781341 0.58 ENSMUST00000108496.2
solute carrier family 1 (neutral amino acid transporter), member 5
chr6_+_60944472 0.57 ENSMUST00000129603.1
multimerin 1
chr18_-_68429235 0.55 ENSMUST00000052347.6
melanocortin 2 receptor
chr6_-_102464667 0.54 ENSMUST00000032159.6
contactin 3
chr14_-_70630149 0.52 ENSMUST00000022694.9
dematin actin binding protein
chr6_-_40951826 0.51 ENSMUST00000073642.5
predicted gene 4744
chr5_+_3571664 0.50 ENSMUST00000008451.5
RIKEN cDNA 1700109H08 gene
chr3_+_79345361 0.50 ENSMUST00000164216.1
predicted gene, 17359
chr12_+_104101087 0.50 ENSMUST00000021495.3
serine (or cysteine) peptidase inhibitor, clade A, member 5
chr1_+_134111233 0.50 ENSMUST00000159963.1
ENSMUST00000160060.1
chitinase 1 (chitotriosidase)
chr1_-_55088156 0.49 ENSMUST00000127861.1
ENSMUST00000144077.1
heat shock protein 1 (chaperonin)
chr13_+_75967704 0.49 ENSMUST00000022081.1
spermatogenesis associated 9
chr16_+_36210403 0.49 ENSMUST00000089628.3
predicted gene 5416
chr1_+_166130467 0.48 ENSMUST00000166860.1
glycoprotein A33 (transmembrane)
chr12_-_76795489 0.47 ENSMUST00000082431.3
glutathione peroxidase 2
chr1_-_55088024 0.47 ENSMUST00000027123.8
heat shock protein 1 (chaperonin)
chr1_-_193273099 0.46 ENSMUST00000009777.2
G0/G1 switch gene 2
chr15_+_62039216 0.46 ENSMUST00000183297.1
plasmacytoma variant translocation 1
chr9_-_18512885 0.45 ENSMUST00000034653.6
mucin 16
chr3_-_106149761 0.45 ENSMUST00000149836.1
chitinase 3-like 3
chr16_-_16869255 0.45 ENSMUST00000075017.4
pre-B lymphocyte gene 1
chr12_-_110696289 0.44 ENSMUST00000021698.6
heat shock protein 90, alpha (cytosolic), class A member 1
chr1_+_136467958 0.44 ENSMUST00000047817.6
kinesin family member 14
chr16_-_19883873 0.44 ENSMUST00000100083.3
RIKEN cDNA A930003A15 gene
chr18_+_23415400 0.43 ENSMUST00000115832.2
ENSMUST00000047954.7
dystrobrevin alpha
chr3_+_41024369 0.43 ENSMUST00000099121.3
La ribonucleoprotein domain family, member 1B
chr1_+_166130238 0.42 ENSMUST00000060833.7
ENSMUST00000166159.1
glycoprotein A33 (transmembrane)
chr5_-_5664196 0.42 ENSMUST00000061008.3
ENSMUST00000054865.6
RIKEN cDNA A330021E22 gene
chr13_-_49248146 0.40 ENSMUST00000119721.1
ENSMUST00000058196.6
sushi domain containing 3
chr17_-_43543639 0.40 ENSMUST00000178772.1
ankyrin repeat domain 66
chr10_+_28668360 0.40 ENSMUST00000060409.6
ENSMUST00000056097.4
ENSMUST00000105516.2
thymocyte selection associated
chr6_-_129275360 0.40 ENSMUST00000032259.3
CD69 antigen
chr13_-_92794809 0.39 ENSMUST00000022213.7
thrombospondin 4
chr16_-_55934845 0.39 ENSMUST00000121129.1
ENSMUST00000023270.7
centrosomal protein 97
chr5_-_73191848 0.39 ENSMUST00000176910.1
furry homolog-like (Drosophila)
chr2_+_29124106 0.39 ENSMUST00000129544.1
senataxin
chr2_-_154892782 0.38 ENSMUST00000166171.1
ENSMUST00000161172.1
eukaryotic translation initiation factor 2, subunit 2 (beta)
chr6_-_125494754 0.38 ENSMUST00000032492.8
CD9 antigen
chr4_-_117125618 0.38 ENSMUST00000183310.1
BTB (POZ) domain containing 19
chr11_-_89302545 0.38 ENSMUST00000061728.3
noggin
chr6_-_78378851 0.38 ENSMUST00000089667.1
ENSMUST00000167492.1
regenerating islet-derived 3 delta
chr17_+_28530834 0.37 ENSMUST00000025060.2
armadillo repeat containing 12
chr1_+_40515362 0.37 ENSMUST00000027237.5
interleukin 18 receptor accessory protein
chr8_+_92901387 0.37 ENSMUST00000104947.2
calpain, small subunit 2
chr2_-_154892887 0.36 ENSMUST00000099173.4
eukaryotic translation initiation factor 2, subunit 2 (beta)
chr3_-_129755305 0.36 ENSMUST00000029653.2
epidermal growth factor
chr10_+_128225830 0.36 ENSMUST00000026455.7
major intrinsic protein of eye lens fiber
chr12_-_110696332 0.36 ENSMUST00000094361.4
heat shock protein 90, alpha (cytosolic), class A member 1
chr11_+_116671658 0.36 ENSMUST00000106378.1
ENSMUST00000144049.1
RIKEN cDNA 1810032O08 gene
chr17_-_13404191 0.35 ENSMUST00000115650.1
predicted gene 8597
chr13_-_111490028 0.34 ENSMUST00000091236.4
GC-rich promoter binding protein 1
chr13_+_44729794 0.34 ENSMUST00000172830.1
jumonji, AT rich interactive domain 2
chr11_-_3504766 0.34 ENSMUST00000044507.5
inositol polyphosphate 5-phosphatase J
chr16_+_19760232 0.34 ENSMUST00000079780.3
ENSMUST00000164397.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chrX_+_136033367 0.33 ENSMUST00000057625.2
adipocyte-related X-chromosome expressed sequence 1
chr9_-_107985863 0.33 ENSMUST00000048568.4
family with sequence similarity 212, member A
chr9_+_108986163 0.33 ENSMUST00000052724.3
urocortin 2
chr7_+_110772604 0.33 ENSMUST00000005829.6
adenosine monophosphate deaminase 3
chr7_-_120982260 0.32 ENSMUST00000033169.8
cerebellar degeneration-related 2
chr2_-_149798701 0.32 ENSMUST00000148202.1
ENSMUST00000139471.1
predicted gene 14133
chr1_-_75133866 0.32 ENSMUST00000027405.4
solute carrier family 23 (nucleobase transporters), member 3
chr16_+_19760195 0.32 ENSMUST00000121344.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr10_+_130322845 0.32 ENSMUST00000042586.8
thymocyte expressed, positive selection associated 1
chr2_+_30061754 0.31 ENSMUST00000149578.1
ENSMUST00000102866.3
SET nuclear oncogene
chr1_-_193035651 0.31 ENSMUST00000016344.7
synaptotagmin XIV
chr5_-_38876693 0.31 ENSMUST00000169819.1
ENSMUST00000171633.1
cytokine-dependent hematopoietic cell linker
chr7_+_44188205 0.31 ENSMUST00000073713.6
kallikrein 1-related peptidase b24
chr3_-_92458715 0.31 ENSMUST00000058142.3
small proline-rich protein 3
chr1_-_45890078 0.30 ENSMUST00000183590.1
predicted gene 5269
chr1_-_79858627 0.30 ENSMUST00000027467.4
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr13_+_38204928 0.29 ENSMUST00000091641.5
ENSMUST00000178564.1
small nuclear ribonucleoprotein 48 (U11/U12)
chr10_-_88356990 0.29 ENSMUST00000020249.1
DNA-damage regulated autophagy modulator 1
chr12_-_17324703 0.29 ENSMUST00000020884.9
ENSMUST00000095820.5
ENSMUST00000127185.1
ATPase, H+ transporting, lysosomal V1 subunit C2
chr1_-_136234113 0.29 ENSMUST00000120339.1
ENSMUST00000048668.8
RIKEN cDNA 5730559C18 gene
chr10_-_62507737 0.29 ENSMUST00000020271.6
serglycin
chr4_-_94928789 0.29 ENSMUST00000030309.5
equatorin, sperm acrosome associated
chr5_-_123749371 0.29 ENSMUST00000182955.1
ENSMUST00000182489.1
ENSMUST00000050827.7
arginine/serine-rich coiled-coil 2
chr4_+_134102581 0.28 ENSMUST00000074690.4
ENSMUST00000070246.2
ENSMUST00000156750.1
UBX domain protein 11
chr14_-_65833963 0.28 ENSMUST00000022613.9
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr11_+_49513618 0.28 ENSMUST00000060434.2
olfactory receptor 1384
chr6_-_7692867 0.28 ENSMUST00000115542.1
ENSMUST00000148349.1
asparagine synthetase
chr11_+_76904475 0.28 ENSMUST00000142166.1
transmembrane and immunoglobulin domain containing 1
chr9_-_53975246 0.28 ENSMUST00000048409.7
ELMO/CED-12 domain containing 1
chr13_+_84222286 0.28 ENSMUST00000057495.8
transmembrane protein 161B
chr1_+_186749368 0.28 ENSMUST00000180869.1
RIKEN cDNA A430105J06 gene
chr14_-_63193541 0.28 ENSMUST00000038229.4
nei like 2 (E. coli)
chr7_+_44216456 0.28 ENSMUST00000074359.2
kallikrein 1-related peptidase b5
chr12_-_110695860 0.28 ENSMUST00000149189.1
heat shock protein 90, alpha (cytosolic), class A member 1
chr2_+_154200371 0.28 ENSMUST00000028987.6
BPI fold containing family B, member 1
chr15_-_101491509 0.27 ENSMUST00000023718.7
RIKEN cDNA 5430421N21 gene
chr4_+_17853451 0.27 ENSMUST00000029881.3
matrix metallopeptidase 16
chr1_-_144249134 0.27 ENSMUST00000172388.1
regulator of G-protein signaling 1
chr2_-_74579379 0.27 ENSMUST00000130586.1
limb and neural patterns
chr4_+_108479081 0.27 ENSMUST00000155068.1
zinc finger, CCHC domain containing 11
chr11_-_69878018 0.27 ENSMUST00000178597.1
transmembrane protein 95
chr19_-_16780822 0.26 ENSMUST00000068156.6
vacuolar protein sorting 13A (yeast)
chrX_+_135993820 0.26 ENSMUST00000058119.7
adipocyte-related X-chromosome expressed sequence 2
chr13_+_20794119 0.26 ENSMUST00000021757.3
acyloxyacyl hydrolase
chr19_-_10203880 0.26 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
flap structure specific endonuclease 1
chr6_-_7693184 0.26 ENSMUST00000031766.5
asparagine synthetase
chr19_-_5845471 0.26 ENSMUST00000174287.1
ENSMUST00000173672.1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr13_+_76579670 0.26 ENSMUST00000126960.1
ENSMUST00000109583.2
multiple C2 domains, transmembrane 1
chr19_-_34166037 0.26 ENSMUST00000025686.7
ankyrin repeat domain 22
chr5_-_123749393 0.26 ENSMUST00000057795.5
ENSMUST00000111515.1
ENSMUST00000182309.1
arginine/serine-rich coiled-coil 2
chrX_-_48594373 0.26 ENSMUST00000088898.4
ENSMUST00000072292.5
zinc finger protein 280C
chr16_-_55934797 0.26 ENSMUST00000122280.1
ENSMUST00000121703.2
centrosomal protein 97
chr1_-_176807124 0.26 ENSMUST00000057037.7
centrosomal protein 170
chr9_-_71592312 0.25 ENSMUST00000166112.1
myocardial zonula adherens protein
chr6_-_41680723 0.25 ENSMUST00000031901.5
transient receptor potential cation channel, subfamily V, member 5
chr17_+_34972687 0.25 ENSMUST00000007248.3
heat shock protein 1-like
chr16_-_59553970 0.25 ENSMUST00000139989.1
beta-gamma crystallin domain containing 3
chr6_+_51470339 0.25 ENSMUST00000094623.3
chromobox 3
chr6_-_7693110 0.25 ENSMUST00000126303.1
asparagine synthetase
chr4_+_21848039 0.24 ENSMUST00000098238.2
ENSMUST00000108229.1
serine/arginine-rich splicing factor 18
chr11_-_69858687 0.24 ENSMUST00000125571.1
tyrosine kinase, non-receptor, 1
chr8_-_80739497 0.24 ENSMUST00000043359.8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr7_+_142434977 0.24 ENSMUST00000118276.1
ENSMUST00000105976.1
ENSMUST00000097939.2
synaptotagmin VIII
chr10_-_62422427 0.24 ENSMUST00000020277.8
hexokinase domain containing 1
chrX_-_19237841 0.24 ENSMUST00000180592.1
predicted gene, 26652
chr9_-_77045788 0.24 ENSMUST00000034911.6
tubulointerstitial nephritis antigen
chr7_-_4752972 0.24 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
cytochrome c oxidase subunit VIb polypeptide 2
chr17_+_47385386 0.24 ENSMUST00000024774.7
ENSMUST00000145462.1
guanylate cyclase activator 1B
chr2_+_35109482 0.24 ENSMUST00000028235.4
ENSMUST00000156933.1
ENSMUST00000028237.8
centrosomal protein 110
chr6_-_83536215 0.24 ENSMUST00000075161.5
actin, gamma 2, smooth muscle, enteric
chr7_+_43950614 0.24 ENSMUST00000072204.4
kallikrein 1-related peptidase b8
chr13_+_44729535 0.24 ENSMUST00000174068.1
jumonji, AT rich interactive domain 2
chr6_-_136941887 0.24 ENSMUST00000111891.1
Rho, GDP dissociation inhibitor (GDI) beta
chr2_+_103424120 0.24 ENSMUST00000171693.1
E74-like factor 5
chr2_+_144527718 0.23 ENSMUST00000028914.2
ENSMUST00000110017.2
polymerase (RNA) III (DNA directed) polypeptide F
chr5_+_32611171 0.23 ENSMUST00000072311.6
ENSMUST00000168707.2
Yamaguchi sarcoma viral (v-yes) oncogene homolog 1
chrX_-_157568983 0.23 ENSMUST00000065806.4
Yy2 transcription factor
chr1_+_70725902 0.23 ENSMUST00000161937.1
ENSMUST00000162182.1
von Willebrand factor C domain-containing protein 2-like
chr3_-_144760841 0.23 ENSMUST00000059091.5
chloride channel calcium activated 1
chr7_+_110768169 0.23 ENSMUST00000170374.1
adenosine monophosphate deaminase 3
chr1_-_17097839 0.23 ENSMUST00000038382.4
junctophilin 1
chr11_-_11970540 0.23 ENSMUST00000109653.1
growth factor receptor bound protein 10
chr11_-_69858723 0.23 ENSMUST00000001626.3
ENSMUST00000108626.1
tyrosine kinase, non-receptor, 1
chr13_+_81657732 0.23 ENSMUST00000049055.6
LysM, putative peptidoglycan-binding, domain containing 3
chr12_-_4592927 0.22 ENSMUST00000170816.1
predicted gene 3625
chr2_+_30845059 0.22 ENSMUST00000041659.5
paired related homeobox 2
chr15_-_95528228 0.22 ENSMUST00000075275.2
NEL-like 2
chr16_+_21794320 0.22 ENSMUST00000181780.1
ENSMUST00000181960.1
RIKEN cDNA 1300002E11 gene
chr10_-_80421847 0.22 ENSMUST00000156244.1
transcription factor 3
chr3_-_106024911 0.22 ENSMUST00000066537.3
ENSMUST00000054973.3
chitinase 3-like 7
chr16_+_77014069 0.22 ENSMUST00000023580.6
ubiquitin specific peptidase 25
chr2_+_130277157 0.21 ENSMUST00000028890.8
ENSMUST00000159373.1
NOP56 ribonucleoprotein
chr14_+_79481164 0.21 ENSMUST00000040131.5
E74-like factor 1
chr17_-_17855188 0.21 ENSMUST00000003762.6
hyaluronan synthase1
chr11_-_61719946 0.21 ENSMUST00000151780.1
ENSMUST00000148584.1
solute carrier family 5 (sodium/glucose cotransporter), member 10
chr10_+_127000709 0.21 ENSMUST00000026500.5
ENSMUST00000142698.1
advillin
chr5_+_110110068 0.21 ENSMUST00000112528.1
zinc finger protein 605
chr3_+_27154020 0.21 ENSMUST00000181124.1
RIKEN cDNA 1700125G22 gene
chr5_-_21785115 0.21 ENSMUST00000115193.1
ENSMUST00000115192.1
ENSMUST00000115195.1
ENSMUST00000030771.5
DnaJ (Hsp40) homolog, subfamily C, member 2
chr14_-_79481268 0.21 ENSMUST00000022601.5
WW domain binding protein 4
chrX_+_72918557 0.21 ENSMUST00000033715.4
NAD(P) dependent steroid dehydrogenase-like
chr2_+_103424056 0.21 ENSMUST00000028609.7
E74-like factor 5
chr11_+_46454921 0.20 ENSMUST00000020668.8
hepatitis A virus cellular receptor 2
chrX_-_51205990 0.20 ENSMUST00000114876.2
muscleblind-like 3 (Drosophila)
chr8_+_47824459 0.20 ENSMUST00000038693.6
claudin 22
chr11_-_33513626 0.20 ENSMUST00000037522.7
RAN binding protein 17
chr13_+_76579681 0.20 ENSMUST00000109589.2
multiple C2 domains, transmembrane 1
chr6_-_118562226 0.20 ENSMUST00000112830.1
ankyrin repeat domain 26
chr13_-_111490111 0.20 ENSMUST00000047627.7
GC-rich promoter binding protein 1
chr3_+_79591356 0.20 ENSMUST00000029382.7
peptidylprolyl isomerase D (cyclophilin D)
chr2_-_144527341 0.20 ENSMUST00000163701.1
ENSMUST00000081982.5
double zinc ribbon and ankyrin repeat domains 1
chr6_-_66896521 0.20 ENSMUST00000065878.3
RIKEN cDNA 4930597O21 gene
chr1_+_137966529 0.19 ENSMUST00000182158.1
RIKEN cDNA A430106G13 gene
chr6_-_97205549 0.19 ENSMUST00000164744.1
ENSMUST00000089287.5
ubiquitin-like modifier activating enzyme 3
chr5_+_17574726 0.19 ENSMUST00000169603.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr1_+_138963709 0.19 ENSMUST00000168527.1
DENN/MADD domain containing 1B

Network of associatons between targets according to the STRING database.

First level regulatory network of Hsf2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0045041 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041)
0.3 1.2 GO:0035566 regulation of metanephros size(GO:0035566)
0.3 1.7 GO:0045585 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.2 0.7 GO:0051659 positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470) maintenance of mitochondrion location(GO:0051659) relaxation of skeletal muscle(GO:0090076)
0.2 0.6 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.2 0.8 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.2 0.5 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.2 1.4 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) axo-dendritic protein transport(GO:0099640)
0.1 0.4 GO:0033624 negative regulation of integrin activation(GO:0033624)
0.1 1.0 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.4 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.4 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.1 0.4 GO:0060300 regulation of cytokine activity(GO:0060300)
0.1 0.5 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.2 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.6 GO:0006868 glutamine transport(GO:0006868)
0.1 0.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.4 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1 0.8 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.2 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.1 0.2 GO:0033189 response to vitamin A(GO:0033189)
0.1 0.6 GO:0051715 cytolysis in other organism(GO:0051715)
0.1 0.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.3 GO:0033368 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
0.1 0.9 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.4 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 0.2 GO:2000521 negative regulation of immunological synapse formation(GO:2000521) regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001188) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
0.1 0.5 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.3 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.1 0.3 GO:0010286 heat acclimation(GO:0010286)
0.1 0.3 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.4 GO:0030913 paranodal junction assembly(GO:0030913)
0.1 0.4 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.6 GO:0032264 IMP salvage(GO:0032264)
0.1 0.3 GO:0061110 dense core granule biogenesis(GO:0061110)
0.1 0.2 GO:1903660 transforming growth factor beta activation(GO:0036363) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 1.3 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.9 GO:0031000 response to caffeine(GO:0031000)
0.1 1.3 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.5 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.1 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.3 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.1 0.1 GO:2000331 regulation of terminal button organization(GO:2000331)
0.1 0.4 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.6 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.1 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.0 0.7 GO:0002176 male germ cell proliferation(GO:0002176)
0.0 0.3 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.2 GO:0035938 estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864)
0.0 0.1 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.0 0.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137) positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.4 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.7 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.1 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.0 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.1 GO:0009196 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.0 0.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.0 0.1 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.1 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.0 GO:0009726 detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726)
0.0 0.2 GO:0044838 cell quiescence(GO:0044838)
0.0 0.5 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.1 GO:0042668 auditory receptor cell fate determination(GO:0042668) negative regulation of forebrain neuron differentiation(GO:2000978)
0.0 0.1 GO:0052203 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.1 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.2 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.0 0.2 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.3 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 0.1 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.0 0.6 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.0 0.1 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.0 0.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.0 0.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0 0.2 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.2 GO:0072053 renal inner medulla development(GO:0072053)
0.0 0.2 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.1 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.1 GO:0071374 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.3 GO:0070431 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0 0.4 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.3 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.2 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0021586 pons maturation(GO:0021586)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:1903405 protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 0.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.5 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.3 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.2 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.2 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.3 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:1903056 regulation of melanosome organization(GO:1903056)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.0 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.1 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.0 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.0 0.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.0 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.6 GO:0006941 striated muscle contraction(GO:0006941)
0.0 0.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.4 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 1.9 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 0.2 GO:2000484 positive regulation of interleukin-8 secretion(GO:2000484)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.3 GO:0030220 platelet formation(GO:0030220)
0.0 0.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 0.0 GO:1904305 negative regulation of gastro-intestinal system smooth muscle contraction(GO:1904305) negative regulation of small intestine smooth muscle contraction(GO:1904348)
0.0 0.2 GO:0046835 carbohydrate phosphorylation(GO:0046835)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 1.0 GO:0031094 platelet dense tubular network(GO:0031094)
0.1 1.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.4 GO:0046691 intracellular canaliculus(GO:0046691)
0.1 0.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.7 GO:0031673 H zone(GO:0031673)
0.1 1.4 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.4 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 0.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.3 GO:0031523 Myb complex(GO:0031523)
0.0 0.4 GO:0005818 aster(GO:0005818)
0.0 0.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0044307 dendritic branch(GO:0044307)
0.0 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 2.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.5 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.4 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.8 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 0.6 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.6 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.0 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.1 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.3 1.8 GO:0002135 CTP binding(GO:0002135)
0.2 0.7 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 0.8 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.2 0.5 GO:0032190 acrosin binding(GO:0032190)
0.1 1.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.9 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.4 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.5 GO:0004568 chitinase activity(GO:0004568)
0.1 0.3 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 0.8 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.3 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 1.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.5 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 0.3 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 1.1 GO:0016918 retinal binding(GO:0016918)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.3 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.6 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.4 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.2 GO:0001847 opsonin receptor activity(GO:0001847)
0.0 1.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.4 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.4 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0070737 protein-glycine ligase activity, elongating(GO:0070737)
0.0 0.1 GO:0050145 uridylate kinase activity(GO:0009041) nucleoside phosphate kinase activity(GO:0050145)
0.0 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.6 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.3 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.0 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0035240 dopamine binding(GO:0035240)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 2.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.5 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.0 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 2.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.1 PID FOXM1 PATHWAY FOXM1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.9 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 0.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.6 REACTOME DEFENSINS Genes involved in Defensins
0.0 2.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.2 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP